CN102166303A - Chinese medicinal composition for treating chronic atrophic gastritis - Google Patents

Chinese medicinal composition for treating chronic atrophic gastritis Download PDF

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CN102166303A
CN102166303A CN 201110085940 CN201110085940A CN102166303A CN 102166303 A CN102166303 A CN 102166303A CN 201110085940 CN201110085940 CN 201110085940 CN 201110085940 A CN201110085940 A CN 201110085940A CN 102166303 A CN102166303 A CN 102166303A
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parts
radix
parched
atrophic gastritis
rhizoma
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CN102166303B (en
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田涛
牟淑善
田晓雷
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Abstract

The invention discloses a Chinese medicinal composition for treating chronic atrophic gastritis, which belongs to the composition of the traditional Chinese medicine and is prepared form offcinal Magnolia bark, poria, Chinese Angelica, red-rooted salvia root, tree peony bark, red peony root, fried yam, fried bighead atractylodes rhizome, common bletilla pseudobulb, bergamot and fried liquorice according to a certain weight ratio. The Chinese medicinal composition has functions of tonifying the spleen and the stomach and promoting the digestion and the circulation of Qi, and can effectively treat chronic atrophic gastritis.

Description

A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis.
Background technology
Chronic atrophic gastritis also claims atrophic gastritis.Be meant the intrinsic body of gland atrophy of mucosa that causes after gastric mucosa surface suffers damage repeatedly, even disappear the common pathological change that thickens of muscular layer of mucosa.Because body of gland atrophy or disappearance, gastric mucosa has attenuation in various degree, and often with intestinal epithelial metaplasia, inflammatory reaction and atypical hyperplasia.This disease is one of digestive system common disease, and in the general crowd of China, the sickness rate of chronic gastritis is very high, and wherein atrophic gastritis accounts for 13.8% of the number examined.The many mistake by chronic superficial gastritis of chronic atrophic gastritis controlled or wrong treatment is transformed, and the minority atrophic gastritis can develop into gastric cancer.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition, it is fast that this Chinese medicine composition has curative effect for the treatment chronic atrophic gastritis, characteristics such as short treating period.
The present invention selects Cortex Magnoliae Officinalis, Poria, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Cortex Moutan, Radix Paeoniae Rubra, Rhizoma dioscoreae (parched), Rhizoma Atractylodis Macrocephalae (parched), Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Citri Sarcodactylis and Radix Glycyrrhizae Preparata to make up, make each efficacy of drugs produce synergism these drug regimens, make it to have the spleen reinforcing stomach function regulating, the effect of removing food stagnancy circulation of qi promoting, thereby can effectively treat chronic atrophic gastritis.
Wherein: Cortex Magnoliae Officinalis: be bark, root bark and the branch skin of Magnoliacea plant Cortex Magnoliae Officinalis and Mount Lushan Cortex Magnoliae Officinalis.The nature and flavor hardship, suffering, temperature.Return spleen, stomach, large intestine channel.Have circulation of qi promoting removing food stagnancy, dampness except that full effect, cure mainly stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the vomiting and diarrhoea of gastral cavity painful abdominal mass.
Poria: be the dry sclerotia of Polyporaceae fungus Poria Poria cocos (Schw.) Wolf.Nature and flavor are sweet, and are light, flat.Go into the heart, lung, spleen channel.Effect with eliminating dampness and diuresis, invigorating the spleen and regulating the stomach.
Radix Angelicae Sinensis: be the root of umbelliferae angelica Angelica sinensis (0liv.) Diels.The nature and flavor temperature, sweet, hot.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, the effect of loosening bowel to relieve constipation.
Radix Salviae Miltiorrhizae: be the dry root and rhizome of dicotyledon Labiatae Labiatae salvia Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge..The nature and flavor hardship is slightly cold.GUIXIN, Liver Channel.Has promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, the effect of removing heat from blood eliminating carbuncle.
Cortex Moutan: be the dry root bark of ranunculaceae peony.Nature and flavor are cold, hardship.GUIXIN, liver, kidney, lung meridian.Effect with clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.
Radix Paeoniae Rubra: be the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall. or river Radix Paeoniae Rubra Paeonia veitchii Lynch.The nature and flavor hardship is slightly cold.Return Liver Channel.Function with clearing away heat and cooling blood, eliminating stasis to stop pain.
Rhizoma dioscoreae (parched): be the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Nature and flavor are sweet, and are flat.Go into lung, spleen, kidney channel.Have invigorating spleen and reinforcing stomach, digestant effect.
Rhizoma Atractylodis Macrocephalae (parched): be the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Nature and flavor hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, the effect of dampness diuretic.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels.
Fructus Citri Sarcodactylis: be the fruit of rutaceae Fructus Citri Sarcodactylis Citrus medica L.var.sarcodactylis Swingle.Nature and flavor suffering, hardship, acid, temperature.Return liver, spleen, lung meridian.Has liver-smoothing, qi-regulating, the effect of stomach function regulating analgesic.Be used for stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite vomiting.
Radix Glycyrrhizae Preparata: for the honey of Radix Glycyrrhizae is smoked processed goods.Nature and flavor are sweet, and are flat.GUIXIN, lung, spleen, stomach warp.Has the spleen reinforcing stomach function regulating, Yiqi and vein recovery.Be used for weakness of the spleen and stomach, fatigue and weakness.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have curative effect preferably in the following weight parts scope: Cortex Magnoliae Officinalis 10-15 part, Poria 25-35 part, Radix Angelicae Sinensis 20-28 part, Radix Salviae Miltiorrhizae 25-35 part, Cortex Moutan 10-15 part, Radix Paeoniae Rubra 10-15 part, Rhizoma dioscoreae (parched) 12-18 part, Rhizoma Atractylodis Macrocephalae (parched) 20-28 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 12-18 part, Fructus Citri Sarcodactylis 10-15 part, Radix Glycyrrhizae Preparata 12-18 part.
Wherein be preferably: 12 parts of Cortex Magnoliae Officinalis, 30 parts in Poria, 24 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 12 parts of Cortex Moutans, 12 parts of Radix Paeoniae Rubra, 15 parts of Rhizoma dioscoreae (parched)s, 24 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 12 parts of Fructus Citri Sarcodactylis, 15 parts of Radix Glycyrrhizae Preparatas.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.For example these crude drug pulverize mix homogeneously can be made powder takes after mixing it with water; Can use decocting, get filtrate after filtration, add antiseptic and make oral liquid; Also can directly take decoction in case of necessity.
Medicine of the present invention has effects such as spleen reinforcing stomach function regulating, removing food stagnancy circulation of qi promoting, and short treating period is evident in efficacy, without any side effects, according to clinical 200 routine patients being observed statistics, takes medicine total effective rate course of treatment total effective rate 85%, two course of treatment 91% of the present invention.
The specific embodiment
Embodiment one, 10 parts of Cortex Magnoliae Officinalis, 25 parts in Poria, 20 parts of Radix Angelicae Sinensis, 25 parts of Radix Salviae Miltiorrhizaes, 10 parts of Cortex Moutans, 10 parts of Radix Paeoniae Rubra, 12 parts of Rhizoma dioscoreae (parched)s, 20 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 12 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 10 parts of Fructus Citri Sarcodactylis, 12 parts of Radix Glycyrrhizae Preparatas.
Embodiment two, 12 parts of Cortex Magnoliae Officinalis, 30 parts in Poria, 24 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 12 parts of Cortex Moutans, 12 parts of Radix Paeoniae Rubra, 15 parts of Rhizoma dioscoreae (parched)s, 24 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 12 parts of Fructus Citri Sarcodactylis, 15 parts of Radix Glycyrrhizae Preparatas.
Embodiment three, 15 parts of Cortex Magnoliae Officinalis, 35 parts in Poria, 28 parts of Radix Angelicae Sinensis, 35 parts of Radix Salviae Miltiorrhizaes, 15 parts of Cortex Moutans, 15 parts of Radix Paeoniae Rubra, 18 parts of Rhizoma dioscoreae (parched)s, 28 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 18 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 15 parts of Fructus Citri Sarcodactylis, process 18 parts of sweet lists.
Be the clinical statistics data that the patient uses medicine of the present invention below:
One, physical data
Accept out-patient's totally 200 examples for medical treatment, male's 123 examples wherein, women's 77 examples, men and women's ratio 1.6: 1,52 years old mean age.
Two, diagnostic criteria
Feed back epigastric discomfort or pain show as irregular persistence epigastrium pain, or inappetence is arranged, feel sick, the abdominal distention belch, tired, become thin, suffer from diarrhoea, the how light or extra dry red wine no fur of body of the tongue.
Three, Therapeutic Method
According to drug weight proportioning of the present invention, weighting raw materials (daily dose), decocting, filter and remove residue is taken at twice, and 15 is a course of treatment.
Four, efficacy assessment standard
Recovery from illness: clinical symptoms, sign disappear or basic the disappearance.
Produce effects: clinical symptoms, sign are obviously improved.
Invalid: sings and symptoms does not have significant change.
Five, therapeutic outcome statistics
Figure BSA00000467898300041
Wherein: total effective rate=cure rate+obvious effective rate

Claims (2)

1. a Chinese medicine composition for the treatment of chronic atrophic gastritis is characterized in that it is to be made by the raw material of following weight portion: Cortex Magnoliae Officinalis 10-15 part, Poria 25-35 part, Radix Angelicae Sinensis 20-28 part, Radix Salviae Miltiorrhizae 25-35 part, Cortex Moutan 10-15 part, Radix Paeoniae Rubra 10-15 part, Rhizoma dioscoreae (parched) 12-18 part, Rhizoma Atractylodis Macrocephalae (parched) 20-28 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 12-18 part, Fructus Citri Sarcodactylis 10-15 part, Radix Glycyrrhizae Preparata 12-18 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by the raw material of following weight portion: 12 parts of Cortex Magnoliae Officinalis, 30 parts in Poria, 24 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 12 parts of Cortex Moutans, 12 parts of Radix Paeoniae Rubra, 15 parts of Rhizoma dioscoreae (parched)s, 24 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 12 parts of Fructus Citri Sarcodactylis, 15 parts of Radix Glycyrrhizae Preparatas.
CN2011100859401A 2011-03-27 2011-03-27 Traditional Chinese medicine composition for treating chronic atrophic gastritis Expired - Fee Related CN102166303B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895549A (en) * 2012-11-13 2013-01-30 李新欣 Traditional Chinese medicine for treating chronic atrophic gastritis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1833688A (en) * 2006-01-09 2006-09-20 陕西东泰制药有限公司 Medicine for treating gastro-duodenal ulcer and chronic gastritis and its prepn.
CN101244203A (en) * 2008-02-03 2008-08-20 李爱英 Chinese medicine for treating acute and chronic gastritis, enteritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1833688A (en) * 2006-01-09 2006-09-20 陕西东泰制药有限公司 Medicine for treating gastro-duodenal ulcer and chronic gastritis and its prepn.
CN101244203A (en) * 2008-02-03 2008-08-20 李爱英 Chinese medicine for treating acute and chronic gastritis, enteritis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
《实用中医药杂志》 20081215 王冬梅等 慢性萎缩性胃炎的中医药治疗近况 810-811 1-2 , 第12期 2 *
《实用中医药杂志》 20100515 张倩等 慢性萎缩性胃炎中医治疗进展 354-355 1-2 , 第05期 2 *
《河南中医》 20080210 杨俊等 中医药治疗慢性萎缩性胃炎研究近况 78-80 1-2 , 第02期 2 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895549A (en) * 2012-11-13 2013-01-30 李新欣 Traditional Chinese medicine for treating chronic atrophic gastritis
CN102895549B (en) * 2012-11-13 2014-03-12 李新欣 Traditional Chinese medicine for treating chronic atrophic gastritis

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