Background technology
Athetosis (athetosis) is found in multiple encephalopathy, and feature is the slow irregular twistings of brothers.Athetosis is the migrans hypermyotonia of far-end of limb and lower action, occurs that the torsion sample of creeping as Lumbricus is slowly wriggled, companion's far-end of limb overextension, as excessively in the wrong in wrist, finger hyperextension etc., and points flexing in succession one by one lentamente; Because too much autokinesis makes affected area can not maintain a certain posture or position.Athetosis type accounts for Their Incidence of Cerebral Palsy type second, and this type, to be difficult to suppress limbs involuntary movement for principal character by will, to comprise face muscle, invades and whole body, because sounding, structure sound organ also more gets involved, therefore normal with aphasis.Pathological changes is at cerebral deep basal nuclei, and the from outside part of cone is main, accounts for cerebral palsy 20%.
The effective medicine of generally recognized as safe is still lacked at present for athetosis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Herba Apocyni veneti [source] Herba Apocyni veneti is Apocynaceae Apocynum crop, perennial wild draft bast fibre plant.Have another name called wild flax, wild tea, bluish dogbane, Semen astragali sinici etc., primary growth on salt-soda soil, desert or riverbank, gully, hillside sandy ground.[function cures mainly] cold nature, bitter but sweet flavor, can resolving heat and reducing pathogenic fire, suppressing the hyperactive liver to relieve the wind syndrome, cures mainly the diseases such as headache, dizzy, insomnia; Leaf is sweet containing Herba Apocyni veneti, has cardiotonic, can treat the diseases such as hypertension.
Fructus Evodiae [source] is the almost ripe fruit of rutaceae Fructus Evodiae Evodia rutaecarpa.[function cures mainly] its bitter in the mouth hot in nature is trembled with fear, and has the merit of heat radiation pain relieving, stopping nausea and vomiting by lowering the adverse flow of QI, is used for the treatment of that liver insufficiency of stomach is trembled with fear, the disease such as headache caused by cloudy turbid superinverse or gastralgia.
Radix Gymnematis Sylvestris [source] medical material Ji Yuan: be root or the browse of dicotyledon medicine asclepiadaceae plant Largeleaf Gymnema.[function cures mainly] clearing away heat and cooling blood; Evacuation of pus is subsided a swelling; Pain relieving granulation promoting.Main air pain of dampness syndrome; Laryngopharynx swelling and pain; Scrofula: acute mastitis; Furuncle; Eczema; Innominate toxic swelling; Venom.
Cortex Moutan [source] is the root bark of Ranunculaceae Paeonia plant Paeonia suffruticosa, containing paeonol, and paeonolide, volatile oil and plant sterol etc.[function cures mainly] Cortex Moutan reduces blood pressure, ease pain, calm, antiinflammatory and refrigeration function; Stronger inhibitory action is had to various pathogens.It is cool in nature, bitter in the mouth, pungent, function heat clearing away, and removing heat from blood and blood, the clear stasis of blood, be applicable to thermal man's blood system, sends out speckle, frightened pain, spits blood, carbuncle and ulcer, the diseases such as traumatic injury.
Cortex Lycii [source] is the root bark of Solanaceae Lycium Fructus Lycii, includes cinnamic acid, multiple aldehydes matter, betanin and linoleic acid etc.; Cortex Lycii has significant refrigeration function, and its decoct can make blood glucose reduce, and have and reduce serum cholesterol and lipotropic effect, the preserved material of Cortex Lycii has the effect reduced blood pressure significantly to animal.It is cold in nature, sweet in the mouth, light.[function cures mainly] removing heat from blood, moves back steaming, and clear eliminating the pathogens from the lung heat, is applicable to asthenia hectic fever night sweat, lung-heat cough with asthma, the haematemesis of bleeding due to blood-heat, epistaxis, carbuncle malignant boil and pulmonary tuberculosis and vascular hypertension etc.
Flos Lonicerae [source] Flos Lonicerae is the alabastrum of caprifoliaceae plant Radix Ophiopogonis, containing chlorogenic acid, and inositol, flavones ingredient etc.[function cures mainly] Flos Lonicerae has antiinflammatory and refrigeration function, and infected by influenza and various pathogens, skin pathomycete have inhibitory action, reflect the heat-clearing toxin-expelling functions of Flos Lonicerae.It is cold in nature, sweet in the mouth, function heat clearing away, removing toxic substances, is applicable to epidemic febrile disease heating, toxic-heat and blood stasis, the disease of the hyperactivity of toxic heat such as skin ulcer, carbuncle, furuncle and phyma.
Myrrha [source] Chinese olive tree section plant Herba Violae tree, Ha Didingshu, the oleo-gum-resin that trunk portion is oozed out.Be divided into natural Myrrha and gum opoponax.[function cures mainly] falls apart blood blood stasis removing, subduing swelling and relieving pain.Control traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Radix Codonopsis [source] Chinese medicine Radix Codonopsis is that campanulaceae herbaceos perennial [function cures mainly] has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.Enhancing immunity, blood vessel dilating, blood pressure lowering, improve microcirculation, strengthen the effect such as hemopoietic function
The root that the Radix Astragali [source] is leguminous plant Radix Astagali or Radix Astragali.Removing fibrous root and root head, dry, section, and life is used or processed with honey is used.[function cures mainly] has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Rhizoma Dioscoreae [source] herbaceos perennial, stem is overgrow, and is often with purple, and tuber is cylindrical, and leaf is to life, avette or oval, flower milky, dioecism.Starch-containing and the protein of tuber.[function cures mainly] spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.
The dry rattan of Caulis Spatholobi [source] leguminous plant spatholobus suberectus Spatholobus suberectus Dunn.[function cures mainly] property is sweet, temperature.Return liver, kidney channel.Function cures mainly: enrich blood, and invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
The rhizome of Rhizoma Imperatae [source] grass perennial herb Herba Imperatae (formal name used at school: Imperata cylindrica).Season in spring and autumn two excavates.Dry.Removing fibrous root and film quality sheath, cutting is raw to be used or parch to black use.[function cures mainly] removing heat from blood, hemostasis, heat clearing away, diuresis.Control calentura excessive thirst.
Rhizoma Polygonati [source] has another name called Rhizoma Polygonati Cirrhifolii, Caput Gallus domesticus ginseng.The dry rhizome of liliaceous plant P. kingianum, Rhizoma Polygonati or Polygonatum cyrtonema Hua.Be used as medicine with rhizome.[function cures mainly] has boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney benefiting functions.Be used for the treatment of weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat such as to be quenched one's thirst the disease.
The fleshy stem that Herba Cistanches [source] is orobanchaceae plant cistanche or Herba Cistanches, fan's Herba Cistanches etc.[function cures mainly] reinforcing the kidney and supporting YANG, loosening bowel to relieve constipation, hard masses softening and resolving.
Semen Astragali Complanati [source] is the mature seed of pulse family annual herb plant astragatus complanatus, taps plant, dries, lay seed when the time of the year when autumn changes into winter, fruit maturation not yet ftractureed.Life is used or is fried and uses.[function cures mainly] tonifying liver, kidney tonifying, improving eyesight, controlling nocturnal emission with astringent drugs.Treating the liver kidney deficiency, soreness of waist and knee joint, blurred vision, seminal emission premature ejaculation, frequent micturition, the enuresis, hematuria, leucorrhea.
Spica Prunellae [source] Spica Prunellae is flowers or the herb of labiate Spica Prunellae, includes triterpenoid saponin and glycoside unit oleanolic acid thereof, volatile oil and vitamin, potassium chloride etc.[function cures mainly] it is cold in nature, bitter in the mouth, pungent, function clearing away liver-fire, Disperse hepatic depression, blood pressure lowering, is applicable to the conjunctival congestion and swelling pain caused by flaming up of liver-fire, ophthalmalgia, photophobia is shed tears, has a headache, dizzy etc.; For the scrofula caused by phlegm-fire pent-up, goiter etc.
Summary of the invention
The present invention aims to provide one and treats athetosic Chinese medicine, by selecting suitable medical material and proportioning thereof, reaches the athetosic object of safe and effective healing.
In order to achieve the above object, the present invention is by the following technical solutions:
One treats athetosic Chinese medicine, it is characterized in that, be prepared from by the medical material of following weight proportion: Herba Apocyni veneti 14 parts, Fructus Evodiae 12 parts, Radix Gymnematis Sylvestris 8 parts, Cortex Moutan 12 parts, Cortex Lycii 10 parts, Flos Lonicerae 12 parts, Myrrha 10 parts, Radix Codonopsis 14 parts, the Radix Astragali 12 parts, Rhizoma Dioscoreae 14 parts, Caulis Spatholobi 10 parts, Rhizoma Imperatae 14 parts, Rhizoma Polygonati 8 parts, Herba Cistanches 9 parts, Semen Astragali Complanati 12 parts, Spica Prunellae 12 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects 80 routine athetosic out-patients-2011 years in June, 2010 altogether between JIUYUE, age 12-47 year, course of disease 0.5-7.Be divided at random: treatment group 50 example, blank group 30 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains safe and effectively can control athetosis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Herba Apocyni veneti 14 grams, Fructus Evodiae 12 grams, Radix Gymnematis Sylvestris 8 grams, Cortex Moutan 12 grams, Cortex Lycii 10 grams, Flos Lonicerae 12 grams, Myrrha 10 grams, Radix Codonopsis 14 grams, the Radix Astragali 12 grams, Rhizoma Dioscoreae 14 grams, Caulis Spatholobi 10 grams, Rhizoma Imperatae 14 grams, Rhizoma Polygonati 8 grams, Herba Cistanches 9 grams, Semen Astragali Complanati 12 grams, Spica Prunellae 12 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of athetosis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: Herba Apocyni veneti 14 grams, Fructus Evodiae 12 grams, Radix Gymnematis Sylvestris 8 grams, Cortex Moutan 12 grams, Cortex Lycii 10 grams, Flos Lonicerae 12 grams, Myrrha 10 grams, Radix Codonopsis 14 grams, the Radix Astragali 12 grams, Rhizoma Dioscoreae 14 grams, Caulis Spatholobi 10 grams, Rhizoma Imperatae 14 grams, Rhizoma Polygonati 8 grams, Herba Cistanches 9 grams, Semen Astragali Complanati 12 grams, Spica Prunellae 12 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of athetosis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: Herba Apocyni veneti 14 grams, Fructus Evodiae 12 grams, Radix Gymnematis Sylvestris 8 grams, Cortex Moutan 12 grams, Cortex Lycii 10 grams, Flos Lonicerae 12 grams, Myrrha 10 grams, Radix Codonopsis 14 grams, the Radix Astragali 12 grams, Rhizoma Dioscoreae 14 grams, Caulis Spatholobi 10 grams, Rhizoma Imperatae 14 grams, Rhizoma Polygonati 8 grams, Herba Cistanches 9 grams, Semen Astragali Complanati 12 grams, Spica Prunellae 12 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of athetosis.Oral, every bu is taken for twice sooner or later.