Background technology
Suppurative pylephlebitis means the suppurative inflammation of branch in main portal vein and the liver thereof.Primary disease is normal with multiple bacterial liver abscess and deposit.The device that supplies that branch of portal vein is supplied with all can cause the generation of primary disease if any suppurative focus.Extent of disease can relate to main portal vein or its branch, or the portal vein genus props up in the whole liver.The internal organs of all genus branch of portal vein drain have suppurative focus person all can cause primary disease.Mainly be because the infection thrombosis in the focus, is invaded and portal system and cause pathological changes such as portal vein suppurative inflammation, multiple liver abscess and septicemia to portal vein along venous return.
Still lack the effective medicine of generally recognized as safe at present for suppurative pylephlebitis.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Pheretima [source] Annelida hard iron earthworm section's animal Pheretima aspergillum [function cures mainly] is cold in nature, salty in the mouth.Heat clearing away arresting convulsion, is relievingd asthma diuresis at collateral dredging; Be used for the unconsciousness due to high fever infantile convulsion and twitch, joint paralysis, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, vascular hypertension.
Fructus Evodiae [source] is the almost ripe fruit of rutaceae Fructus Evodiae Evodia rutaecarpa.[function cures mainly] its bitter in the mouth hot in nature is cold, and the merit of heat radiation pain relieving, stopping nausea and vomiting by lowering the adverse flow of QI is arranged, and is used for the treatment of that the liver insufficiency of stomach is cold, diseases such as the headache due to the cloudy turbid superinverse or gastralgia.
Radix Gymnematis Sylvestris [source] medical material Ji Yuan: be root or the browse of dicotyledon medicine asclepiadaceae plant Largeleaf Gymnema.[function cures mainly] clearing away heat and cooling blood; The evacuation of pus detumescence; The pain relieving granulation promoting.The main air pain of dampness syndrome; Laryngopharynx swelling and pain; Scrofula; Acute mastitis; Furuncle; Eczema; Innominate toxic swelling; Venom.
Fructus Forsythiae [source] Fructus Forsythiae is the fruit of Oleaceae plant Fructus Forsythiae, includes volatile oil, forsythol, flavonoid glycoside, alkaloid etc.; [function cures mainly] Fructus Forsythiae has broad-spectrum antibacterial action, and tell in antiinflammatory, town, diuresis and heart tonifying; Contained flavonoid glycoside can strengthen the density of blood capillary, its cold nature, bitter in the mouth, heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, be applicable to warm, erysipelas, macule, carbuncle and ulcer toxic swelling and anaphylactoid purpura etc.
Radix Isatidis [source] Radix Isatidis is the root of Cruciferae Folium Isatidis platymiscium ancient name for Chinese cabbage orchid and careless Folium Isatidis, contains Radix Isatidis indigo glycoside, isatan B, B--sitosterol etc.; Remarkable antivirus action is arranged.Various pathogens is had inhibitory action, and it is cold in nature, bitter in the mouth.[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving is applicable to that influenzal encephalitis, encephalitis B, pneumonia, erysipelas, pyretic toxicity send out speckle, acute catarrhal conjunctivitis, herpes etc.
Oviductus Ranae [source] is Chinese forest frog oil, Oviductus Ranae again, the oviducal dry products of the female Kazakhstan toad frog, and the general natural nutrition composition that toad oil medical material includes mainly comprises: crude protein, crude fat, ash, nitrogen-free extract etc.[function cures mainly] the kidney invigorating and essence nourishing, nourishing YIN and moistening the lung are used for physical weakness, imbalance after being ill, spiritlessness and weakness, deficiency of the kidney spirit is not enough, and palpitation and insomnia, night sweat are more than, the consumptive disease hemoptysis of coughing.
Radix Rubi Parvifolii [source] is in feverfew Japan Herba Gnaphalii Affinis herb.Sweet, cold.[function cures mainly] induces sweat, and heat clearing away makes eye bright, the effect of diuresis.The treatment flu, cough, headache, laryngalgia, conjunctival congestion nebula Zhang, a state in the Zhou Dywnasty, urine heat-blockage, stranguria with turbid discharge, leucorrhea, carbuncle, furuncle.
Radix Berberidis [source] is in root bark or the peel of stem of the black pearl of Berberidaceae plant thorn, berberis brachypoda Maxim, black stone pearl etc.Cold in nature, little hardship.[function cures mainly] heat clearing away, dampness removing, the effect of dissipating blood stasis.The treatment bloody dysentery, jaundice, pharyngalgia, conjunctival congestion, traumatic injury.
Caulis Bauhihiae Championii [source] is in the stem of leguminous plant Caulis Bauhiniae Championii.Toil, flat, nontoxic.[function cures mainly] dispels the wind, the effect of blood stasis removing, pain relieving.Treatment rheumatic ostalgia, traumatic injury.
Root and the stem of Radix Chimonanthi praecocis [source] Calycanthaceae plant Chimonanthus praecox (L.) Link..Xin Wen is nontoxic.[function cures mainly] Eradicates wind is regulated the flow of vital energy, and promoting blood circulation and detoxication is controlled asthma, epersalgia cough, rheumatic arthralgia." Kweiyang medicinal herbs among the people ": dispelling the wind and dampness pathogens osteodynia, abdominal pain due to stagnation of QI." Guizhou side's medicine among the people collection ": calmness, cough-relieving is relievingd asthma.
Radix Polygoni Multiflori [source] is the perennial winding of Polygonaceae liana.Root is elongated, the loose tuber of terminal one-tenth, and the appearance bronzing is to crineous.But the tuber of plant, rattan and leaf be hyoscine all.[function cures mainly] detoxifcation, loosening bowel to relieve constipation, eliminating carbuncle; Enrich and benefit essence and blood, black beard and hair, bone and muscle strengthening, invigorating the liver and kidney.Promote hemopoietic function, strengthen immunologic function
Bulbus Lilii [source] Liliaceae lilium perennial herb bulbous plant, it is spent, the squamous stem all can be used as medicine, and is a kind of flowers of dietotherapeutic.[function cures mainly] cold nature is flat, have relieve inflammation or internal heat, lung moistening, the effect of calming the nerves.
Radix Morindae Officinalis [source] is the dry root of dicotyledon Rubiaceae (Rubiaceae) Radix Morindae Officinalis (Morinda officinalis How.).[function cures mainly] cures mainly that impotence and seminal emission, cold womb are infertile, menoxenia, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity are soft.
The Rhizoma Anemarrhenae [source] is the rhizome of the liliaceous plant Rhizoma Anemarrhenae, contain multiple Saponin and Saponin it, contain two kinds of flavonoids in addition and become Mengiferin etc.[function cures mainly] Rhizoma Anemarrhenae has tangible refrigeration function, and popularity hemorrhagic fever, epidemic encephalitis type B, pulmonary tuberculosis hectic fever all have obvious curative effects.It is cold in nature, sweet in the mouth, hardship, and function clearing away heat-fire, nourshing Yin and drynsessmoistening prescription is applicable to lung-heat cough with asthma or cough due to yin deficiency, dysphoria with smothery sensation is quenched one's thirst, hectic fever due to YIN-deficiency consumptive fever, dysuria, diseases such as constipation due to dry stool.
Flos Lonicerae [source] Flos Lonicerae is the caprifoliaceae plant alabastrum of Radix Ophiopogonis, contains chlorogenic acid, inositol, flavones ingredient etc.[function cures mainly] Flos Lonicerae has antiinflammatory and refrigeration function, and influenza virus and various pathogens, skin pathomycete are had inhibitory action, has reflected the heat-clearing toxin-expelling functions of Flos Lonicerae.It is cold in nature, sweet in the mouth, and the function heat clearing away, detoxifcation is applicable to the epidemic febrile disease heating, toxic-heat and blood stasis, the disease of hyperactivity of toxic heat such as skin ulcer, carbuncle, furuncle and phyma.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of suppurative pylephlebitis, by selecting suitable medical material and proportioning thereof, reaches the purpose of safe and effective healing suppurative pylephlebitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of suppurative pylephlebitis, it is characterized in that, be prepared from by the medical material of following weight proportion: 8 parts of Pheretimas, 12 parts of Fructus Evodiaes, 12 parts of Radix Gymnematis Sylvestriss, 14 parts of Fructus Forsythiaes, 14 parts of Radix Isatidis, 1 part of Oviductus Ranae, 8 parts of Radix Rubi Parvifoliis, 8 parts of Radix Berberidis, 6 parts of Caulis Bauhihiae Championiis, 6 parts of Radix Chimonanthi praecocis, 12 parts of Radix Polygoni Multiflori, 10 parts of Bulbus Liliies, 4 parts of Radix Morindae Officinaliss, 8 parts of the Rhizoma Anemarrhenaes, 10 parts of Flos Loniceraes.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
The inventor collects the out-patient of 85 routine suppurative pylephlebitis in November, 2009-2011 altogether between year JIUYUE, age 12-52 year, course of disease 0.5-7.Be divided at random: 60 examples are organized in treatment, blank group 25 examples.Data there was no significant differences such as two groups of ages, the state of an illness have comparability.
2, test method
2.1 the capsule that oral the present invention makes according to specific embodiment 1 is organized in treatment, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsule, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms does not have being clearly better or increases the weight of.
3.2 treatment statistical result sees Table 1.
Table 1 liang group curative effect relatively
Group |
n |
Recovery from illness |
Take a turn for the better |
Invalid |
Total effective rate (%) |
The treatment group |
60 |
3(5%) |
45(75%) |
12(20%) |
80% |
Blank group |
25 |
0 |
4(16%) |
21(84%) |
16% |
As seen, the medicine that makes of the present invention can safe and effectively be controlled suppurative pylephlebitis.
The specific embodiment
In order to understand better and to implement the present invention, further specify the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take by weighing: Pheretima 8 grams, Fructus Evodiae 12 grams, Radix Gymnematis Sylvestris 12 grams, Fructus Forsythiae 14 grams, Radix Isatidis 14 grams, Radix Rubi Parvifolii 8 grams, Radix Berberidis 8 grams, Caulis Bauhihiae Championii 6 grams, Radix Chimonanthi praecocis 6 grams, Radix Polygoni Multiflori 12 grams, Bulbus Lilii 10 grams, Radix Morindae Officinalis 4 grams, the Rhizoma Anemarrhenae 8 grams, Flos Lonicerae 10 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate concentrates, and drying adds Oviductus Ranae 1 gram, incapsulates shell, namely gets the capsule that meets 1 day consumption of normal adult.
Be used for the treatment of suppurative pylephlebitis.Oral, divide sooner or later every day and take for twice.
Specific embodiment 2
Take by weighing: Pheretima 8 grams, Fructus Evodiae 12 grams, Radix Gymnematis Sylvestris 12 grams, Fructus Forsythiae 14 grams, Radix Isatidis 14 grams, Radix Rubi Parvifolii 8 grams, Radix Berberidis 8 grams, Caulis Bauhihiae Championii 6 grams, Radix Chimonanthi praecocis 6 grams, Radix Polygoni Multiflori 12 grams, Bulbus Lilii 10 grams, Radix Morindae Officinalis 4 grams, the Rhizoma Anemarrhenae 8 grams, Flos Lonicerae 10 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate concentrates, and drying adds Oviductus Ranae 1 gram, pulverizes, and namely gets the powder that meets 1 day consumption of normal adult.
Be used for the treatment of suppurative pylephlebitis.Oral, divide sooner or later every day and take for twice.
Specific embodiment 3
Take by weighing: Pheretima 8 grams, Fructus Evodiae 12 grams, Radix Gymnematis Sylvestris 12 grams, Fructus Forsythiae 14 grams, Radix Isatidis 14 grams, Radix Rubi Parvifolii 8 grams, Radix Berberidis 8 grams, Caulis Bauhihiae Championii 6 grams, Radix Chimonanthi praecocis 6 grams, Radix Polygoni Multiflori 12 grams, Bulbus Lilii 10 grams, Radix Morindae Officinalis 4 grams, the Rhizoma Anemarrhenae 8 grams, Flos Lonicerae 10 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate concentrates, and drying adds Oviductus Ranae 1 gram, adds an amount of dextrin and correctives again, granulates according to this area common process, and packing can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of suppurative pylephlebitis.Oral, divide sooner or later every day and take for twice.