CN110036119A - 卵巢癌生物标记及其应用 - Google Patents

卵巢癌生物标记及其应用 Download PDF

Info

Publication number
CN110036119A
CN110036119A CN201780051204.XA CN201780051204A CN110036119A CN 110036119 A CN110036119 A CN 110036119A CN 201780051204 A CN201780051204 A CN 201780051204A CN 110036119 A CN110036119 A CN 110036119A
Authority
CN
China
Prior art keywords
type
oophoroma
cutting
victory peptide
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201780051204.XA
Other languages
English (en)
Other versions
CN110036119B (zh
Inventor
童宝玲
蔡有光
沈仁达
周松男
简静香
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncolock Co ltd
Original Assignee
Oncolock Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolock Co ltd filed Critical Oncolock Co ltd
Publication of CN110036119A publication Critical patent/CN110036119A/zh
Application granted granted Critical
Publication of CN110036119B publication Critical patent/CN110036119B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57449Specifically defined cancers of ovaries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4716Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

一种生物标记、方法及检验套组,用于辨识及筛检卵巢癌以及监控卵巢癌的治疗。

Description

PCT国内申请,说明书已公开。

Claims (27)

  1. PCT国内申请,权利要求书已公开。
CN201780051204.XA 2017-09-20 2017-09-20 卵巢癌生物标记及其应用 Active CN110036119B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/102407 WO2019056199A1 (zh) 2017-09-20 2017-09-20 卵巢癌生物标记及其应用

Publications (2)

Publication Number Publication Date
CN110036119A true CN110036119A (zh) 2019-07-19
CN110036119B CN110036119B (zh) 2024-01-23

Family

ID=65809497

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780051204.XA Active CN110036119B (zh) 2017-09-20 2017-09-20 卵巢癌生物标记及其应用

Country Status (5)

Country Link
EP (1) EP3686286B1 (zh)
JP (1) JP7023942B2 (zh)
CN (1) CN110036119B (zh)
SG (1) SG11202002529TA (zh)
WO (1) WO2019056199A1 (zh)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030124579A1 (en) * 2001-09-05 2003-07-03 Eos Biotechnology, Inc. Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
WO2006034032A2 (en) * 2004-09-17 2006-03-30 The Johns Hopkins University Biomarkers for breast cancer
CN101268367A (zh) * 2005-06-24 2008-09-17 赛弗吉生物系统公司 卵巢癌的生物标记
CN102654502A (zh) * 2011-03-02 2012-09-05 上海交通大学附属第一人民医院 慢性乙型肝炎肝纤维化的蛋白标记物及其检测方法
CN102851388A (zh) * 2012-09-29 2013-01-02 山东大学齐鲁医院 一种用于鉴别卵巢癌易感性的分子标记、试剂盒及其鉴别方法
CN103739667A (zh) * 2013-09-24 2014-04-23 上海宇研生物技术有限公司 卵巢癌特异的肿瘤抗原肽及其制备方法
US20170218455A1 (en) * 2014-06-18 2017-08-03 Clear Gene, Inc. Methods, compositions, and devices for rapid analysis of biological markers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
US4704692A (en) 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5733743A (en) 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US6265150B1 (en) 1995-06-07 2001-07-24 Becton Dickinson & Company Phage antibodies
EP2051077A3 (en) * 2003-10-07 2009-05-27 Millennium Pharmaceuticals, Inc. Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
US20110256560A1 (en) * 2008-10-20 2011-10-20 University Health Network Methods and compositions for the detection of ovarian cancer
ES2528799T3 (es) * 2008-11-22 2015-02-12 Astute Medical, Inc. Métodos para el pronóstico de insuficiencia renal aguda
JP6454360B2 (ja) * 2014-05-28 2019-01-16 ラントメネン・アーエス−ファクトール・アーベー 抗分泌因子複合体アッセイ

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030124579A1 (en) * 2001-09-05 2003-07-03 Eos Biotechnology, Inc. Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
WO2006034032A2 (en) * 2004-09-17 2006-03-30 The Johns Hopkins University Biomarkers for breast cancer
CN101268367A (zh) * 2005-06-24 2008-09-17 赛弗吉生物系统公司 卵巢癌的生物标记
CN102654502A (zh) * 2011-03-02 2012-09-05 上海交通大学附属第一人民医院 慢性乙型肝炎肝纤维化的蛋白标记物及其检测方法
CN102851388A (zh) * 2012-09-29 2013-01-02 山东大学齐鲁医院 一种用于鉴别卵巢癌易感性的分子标记、试剂盒及其鉴别方法
CN103739667A (zh) * 2013-09-24 2014-04-23 上海宇研生物技术有限公司 卵巢癌特异的肿瘤抗原肽及其制备方法
US20170218455A1 (en) * 2014-06-18 2017-08-03 Clear Gene, Inc. Methods, compositions, and devices for rapid analysis of biological markers

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
L BJØRGE等: "Ascitic complement system in ovarian cancer", 《BRITISH JOURNAL OF CANCER》 *
L BJØRGE等: "Ascitic complement system in ovarian cancer", 《BRITISH JOURNAL OF CANCER》, vol. 92, 1 March 2005 (2005-03-01), pages 897 *
MIN SOON CHO等: "Autocrine Effects of Tumor-Derived Complement", 《CELL REP.》 *
MIN SOON CHO等: "Autocrine Effects of Tumor-Derived Complement", 《CELL REP.》, vol. 6, no. 6, 1 March 2014 (2014-03-01), pages 3 - 4, XP055478089, DOI: 10.1016/j.celrep.2014.02.014 *
MIN SOON CHO等: "Complement component 3 (C3) is regulated by TWIST1 and mediates epithelial-mesenchymal transition (EMT)", 《J IMMUNOL.》 *
MIN SOON CHO等: "Complement component 3 (C3) is regulated by TWIST1 and mediates epithelial-mesenchymal transition (EMT)", 《J IMMUNOL.》, vol. 196, no. 3, 1 February 2016 (2016-02-01), pages 1 - 17 *

Also Published As

Publication number Publication date
JP2020534506A (ja) 2020-11-26
CN110036119B (zh) 2024-01-23
EP3686286A1 (en) 2020-07-29
SG11202002529TA (en) 2020-04-29
EP3686286C0 (en) 2023-11-08
JP7023942B2 (ja) 2022-03-03
EP3686286A4 (en) 2021-07-28
EP3686286B1 (en) 2023-11-08
WO2019056199A1 (zh) 2019-03-28

Similar Documents

Publication Publication Date Title
AU2017200281B2 (en) S100a4 antibodies and therapeutic uses thereof
RU2651513C2 (ru) Новое антитело для диагностики и (или) прогнозирования рака
HUE033628T2 (en) Method for detecting pancreatic cancer
WO2003048302A2 (en) Identifying anti-tumor targets or agents by lipid raft immunization and proteomics
CN103797032B (zh) 抗b7-h6多肽的b7-h6治疗性活性单克隆抗体
CN107108733B (zh) 抗活性型gip抗体
CN109564222A (zh) 利用钾离子通道蛋白的诊断癌症用组合物
CN102504027A (zh) 一种多表位tk1抗体的制备及其在人群体检筛查中早期肿瘤检测和风险预警中的应用
TWI667479B (zh) 乳癌生物標記
EP2984108B1 (en) Anti-s100a7 antibodies for the treatment and diagnosis of cancer
CN110036119A (zh) 卵巢癌生物标记及其应用
EP2310414B1 (en) Pax 5 monoclonal antibody
TWI702400B (zh) 偵側卵巢癌之方法、監控卵巢癌病患之卵巢癌發展之方法及可辨識切割型c3多胜肽之試劑的用途
CN111670201A (zh) 一种Her2伴随诊断免疫组化检测抗体及其应用
CN110865184B (zh) Srsp蛋白和srsp抗原表位肽的应用及诊断和治疗肿瘤的产品
CN102786597B (zh) 抗ercc1单克隆抗体2e12及其用途
KR102168417B1 (ko) 디프테리아 독소에 대해 특이적으로 결합하는 단일클론항체, 이를 생산하는 하이브리도마 세포주 및 이의 용도
CN102786598B (zh) 抗ercc1 单克隆抗体4f9 及其用途

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40011229

Country of ref document: HK

GR01 Patent grant
GR01 Patent grant