CN109998951A - A kind of sun-proof whitening and skin-protecting agent and preparation method thereof - Google Patents
A kind of sun-proof whitening and skin-protecting agent and preparation method thereof Download PDFInfo
- Publication number
- CN109998951A CN109998951A CN201910264463.1A CN201910264463A CN109998951A CN 109998951 A CN109998951 A CN 109998951A CN 201910264463 A CN201910264463 A CN 201910264463A CN 109998951 A CN109998951 A CN 109998951A
- Authority
- CN
- China
- Prior art keywords
- skin
- sun
- protecting agent
- whitening
- proof
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of sun-proof whitening and skin-protecting agent, it include the raw material of following parts by weight: citrus bark extract: 0.5~1.5 part, 1~10 part of piceatannol, 1~40 part of moisturizer, 0.01~2.00 part of chelating agent, 0.05~5.00 part of thickener, 0.1~30.0 part of emollient, 0.01~40.00 part of skin conditioning agent, 100 parts of water;And provide preparation method.The skin conditioner can whitening, lighten the stain, achieve the effect that deep layer skin care;In the present invention, using piceatannol as ultraviolet absorber, product is enabled to absorb ultraviolet light strongly, shift light-wave energy, achieved the purpose that effectively sun-proof.The present invention is safe and reliable, and proportion rationally, is able to satisfy demand of the different crowd to health and visual sense of beauty.Using sun-proof whitening and skin-protecting agent proposed by the present invention, a series of skin-protection products such as lotion, moisturizer, face cream, sleep mask can be needed to configure into according to product.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of skin conditioner and its preparation with sun-proof whitening function
Method.
Background technique
Nails are pursued always with Bai Weimei since ancient times, so-called " a white screening hundred is ugly ".With the development of society, people
Foundation cream class product is no longer needed, but fundamentally seeks the method for whitening and skin-protecting.Therefore, it is no lack of the beauty of type multiplicity on the market
White skin-protection product.However, most of such product all only focuses on the whitening function on surface, ultraviolet radiation is but had ignored to skin
The influence of skin pigment deposition.
Pigmentation is that human skin causes skin that different colours, different range and the different depths is presented for various reasons
Pigment change, pigment anomaly increases.When skin contact ultraviolet light, a kind of brown pigment for being Mai Laning will be generated, and wheat
The effect of drawing peaceful script is to protect the skin from uv damage, but after the completion of its protection task, just will become dirt stripping
It falls.When body metabolism is not good enough, partial pigment can stay in skin surface, form blackspot, therefore want inherently to carry out
Sun-proof whitening needs to consider influence of the ultraviolet radiation to pigment deposition.
Summary of the invention
For the prior art, the purpose of the present invention is to solve the above problem, provide a kind of sun-proof whitening and skin-protecting agent and its
Preparation method.It is obscure that skin conditioner provided by the invention can be effectively improved skin, bright color, has significant sun-proof whitening shield
Skin effect.The present invention not only has the advantage of most of whitening and skin-protecting agent on the market, also compensates for the deficiency of such product.Bright spot
It is that joined this sun-proof optical filtering molecule of piceatannol makes this product due to the strong absorption to piceatannol to ultraviolet light
With good sun-proof whitening effect.
The purpose of the present invention is achieved through the following technical solutions: a kind of sun-proof whitening and skin-protecting agent proposed by the present invention, packet
It includes the raw material of following parts by weight: citrus bark extract: 0.5~1.5 part, 1~10 part of piceatannol, 1~40 part of moisturizer, chelating
0.01~2.00 part of agent, 0.05~5.00 part of thickener, 0.1~30.0 part of emollient, 0.01~40.00 part of skin conditioning agent,
100 parts of water.
Further, in the present invention, the moisturizer includes glycerol, glycerine, reed fragrant plant glue, at least one in sorbierite
Kind.
The chelating agent includes at least one of citric acid, EDETATE SODIUM.
The thickener includes at least one of carbomer, Sodium Polyacrylate, triethanolamine.
The emollient include ceteareth -25, dimethyl silicone polymer, hexadecanol, in mineral oil at least
It is a kind of.
The skin conditioning agent includes at least one of hyaluronic acid, levulan.
The citrus bark extract uses carbon dioxide supercritical extraction technology.The piceatannol is ultraviolet absorber.
Meanwhile the present invention also provides the preparation methods of above-mentioned sun-proof whitening and skin-protecting agent, comprising the following steps:
(1) water phase pot, stirring is added in the water for having determined that parts by weight, moisturizer, chelating agent, thickener;It is heated to
80-85 DEG C, dispersion stirs evenly, as water phase;
(2) emollient for determining parts by weight is added in oily phase pot, is heated to 75-80 DEG C, is stirred evenly after thawing, made
For oily phase;
(3) water phase and oil phase material are pumped into emulsion pot, homogeneous, stirring cooling when temperature is down to 40-45 DEG C, adds
Skin conditioning agent, the citrus bark extract, piceatannol for entering determining parts by weight, stir evenly, are cooled below 38 DEG C
When stop stirring, as gained.
Compared with prior art, the skin conditioner provided by the invention with sun-proof whitening function has the following beneficial effects:
The present invention can serve as the substitute of body material, absorb the ultraviolet light for generating the wavelength of harm, shift light wave energy
Amount reaches and resists ultraviolet light, prevents the pigmented effect of human skin, so that further skin whitening, lightens the stain.
Detailed description of the invention
Fig. 1 is to be dissolved in when the piceatannol concentration as ultraviolet absorber of methanol is 0.0226mmol/L being irradiated with a laser
Ultraviolet spectrogram after different moments.
Specific embodiment
The present invention provides a kind of sun-proof whitening and skin-protecting agent and preparation method thereof, to keep technical solution of the present invention brighter
Really, it is described in detail below with several preferable specific embodiments.Specific embodiment described herein is only used to explain
The present invention is not intended to limit the present invention.
The embodiment of the present invention provides a kind of sun-proof whitening and skin-protecting agent, the raw material including following parts by weight:
0.5~1.5 part of citrus bark extract, the citrus bark extract uses carbon dioxide supercritical extraction technology;It is white
1~10 part of skin China fir alcohol, piceatannol are strong ultraviolet absorber;1~40 part of moisturizer, 0.01~2.00 part of chelating agent, increase
Thick dose 0.05~5.00 part, 0.1~30.0 part of emollient, 0.01~40.00 part of skin conditioning agent, 100 parts of water.
In invention, the moisturizer includes but is not limited at least one of glycerol, glycerine, reed fragrant plant glue, sorbierite;
The chelating agent includes but is not limited at least one of citric acid, EDETATE SODIUM;The thickener includes but is not limited to card wave
At least one of nurse, Sodium Polyacrylate, triethanolamine;The emollient includes but is not limited to ceteareth -25, gathers
At least one of dimethyl siloxane, hexadecanol, mineral oil;The skin conditioning agent includes but is not limited to hyaluronic acid, fruit
At least one of glycan.In moisturizer, chelating agent, thickener, emollient and skin conditioning agent, if containing two or more
Component can be any proportion between each component.
As shown in Figure 1, using piceatannol as ultraviolet absorber in the present invention, the ultraviolet absorber ultraviolet band have compared with
Wide absorption region and preferable absorption intensity, and after the laser irradiation of different moments, it is still able to maintain preferably in ultraviolet band
Absorption.
Embodiment: respectively according to each group distribution ratio and parts by weight content specified in the following table 1, there is sun-proof whitening to make for preparation
Skin conditioner, basic step are as follows:
(1) by the deionized water investment water phase pot of embodiment 1-6 in table 1, Sodium Polyacrylate, carbomer, three second is added
Hydramine is added to complete swelling and uses reed fragrant plant glue, glycerol, the pre-dispersed good hyaluronic acid of glycerine, EDETATE SODIUM liter is then added
Temperature is to 85 DEG C, insulated and stirred 20 minutes, as water phase;
(2) dimethyl silicone polymer, ceteareth -25 are put into oily phase pot and is warming up to 80 DEG C, stirred evenly, make
For oily phase;
(3) water phase and oil phase material are pumped into emulsion pot, are stirred homogeneous 3 minutes, opened cooling water, be cooled to 65 DEG C,
Triethanolamine is added, stirring is cooled to 45 DEG C, and citrus bark extract, piceatannol is added, and it stirs 20 minutes, is cooled to room temperature,
Discharging.
Reference examples in table 1 are free of ultraviolet absorber piceatannol in component therein, and blank example is deionized water.
The preparation process of reference examples and above-described embodiment 1-6 are essentially identical, and difference is only to be added without piceatannol in step (3).
The sun-proof whitening and skin-protecting agent prescription total weight of embodiment 1-6, reference examples and blank example are 100 parts by weight.
The component proportion and parts by weight content of 1 embodiment 1-6 of table, reference examples and blank example
Ingredient names | Reference examples | Embodiment 1 | Embodiment 2 | Embodiment 3 |
EDETATE SODIUM | 0.02 | 0.02 | 0.02 | 0.02 |
Reed fragrant plant glue | 0.20 | 0.20 | 0.20 | 0.20 |
Glycerol | 5.00 | 5.00 | 5.00 | 5.00 |
Glycerine | 3.00 | 3.00 | 3.00 | 3.00 |
Hyaluronic acid | 0.10 | 0.10 | 0.10 | 0.10 |
Levulan | 0.10 | 0.10 | 0.10 | 0.10 |
Sodium Polyacrylate | 0.12 | 0.12 | 0.12 | 0.12 |
Carbomer | 0.10 | 0.10 | 0.10 | 0.10 |
Triethanolamine | 0.50 | 0.50 | 0.50 | 0.50 |
Dimethyl silicone polymer | 1.50 | 1.50 | 1.50 | 1.50 |
Ceteareth -25 | 1.50 | 1.50 | 1.50 | 1.50 |
Citrus bark extract | 1.00 | 1.00 | 1.00 | 1.00 |
Piceatannol | 0 | 3.60 | 4.30 | 5.50 |
Deionized water | 86.86 | 83.26 | 82.56 | 81.36 |
Continued 1
Ingredient names | Embodiment 4 | Embodiment 5 | Embodiment 6 | Blank example |
EDETATE SODIUM | 0.02 | 0.02 | 0.02 | 0 |
Reed fragrant plant glue | 0.20 | 0.20 | 0.20 | 0 |
Glycerol | 5.00 | 5.00 | 5.00 | 0 |
Glycerine | 3.00 | 3.00 | 3.00 | 0 |
Hyaluronic acid | 0.10 | 0.10 | 0.10 | 0 |
Levulan | 0.10 | 0.10 | 0.10 | 0 |
Sodium Polyacrylate | 0.12 | 0.12 | 0.12 | 0 |
Carbomer | 0.10 | 0.10 | 0.10 | 0 |
Triethanolamine | 0.50 | 0.50 | 0.50 | 0 |
Dimethyl silicone polymer | 1.50 | 1.50 | 1.50 | 0 |
Ceteareth -25 | 1.50 | 1.50 | 1.50 | 0 |
Citrus bark extract | 1.00 | 1.00 | 1.00 | 0 |
Piceatannol | 6.40 | 7.20 | 8.50 | 0 |
Deionized water | 80.46 | 79.66 | 78.36 | 100.00 |
Normal individual trial evaluation effect confirmatory experiment:
Tested material and subject: for the practical effect of test product, to embodiment 1-6 and reference examples and blank example system
The sample obtained has carried out crowd respectively and has been applicable in investigation, and the above tested material is distributed to the subject that 320 ages are 20-40 years old,
Wherein male 160, women 160, subject is that skin is obscure, without dermopathic volunteer.Subject is pressed into men and women's ratio
Example is randomly divided into 8 groups, carries out normal individual trial evaluation to the sun-proof whitening and skin-protecting agent of reference examples, embodiment 1-6 and blank example respectively.
The specific operation method is as follows: after subject cleans facial skin, drying, by reference examples, embodiment 1-6 and blank example
Sun-proof whitening and skin-protecting agent take 1g be applied to right side cheek, left cheek is without any processing, as sun-proof whitening and skin-protecting agent
Test comparison area.Tested period face does not smear any other cosmetics or drug, and continuous use checks using effect in 30 days.
Using effect criterion is as follows: 1: it is significant effective, and 2: effectively;3: invalid.Wherein significant is effectively right side cheek
The colour of skin is obviously shallower than left cheek;Effectively it is shallower than left cheek for the right side cheek colour of skin;It is in vain right side cheek and left cheek
The colour of skin does not have significant change.
It is as shown in table 2 that subject tries out evaluation result.
2 subject of table tries out evaluation result
Conclusion: in sun-proof whitening and skin-protecting agent of the invention, it is added to whole components (citrus bark extract, piceatannol)
Embodiment 1-6 (effectively significant >=23) (significant effectively=3 than a reference examples for only addition separate constituent (citrus bark extract)
Example) effect is more preferable.Comparative example 1-6 can be seen that increasing with piceatannol content, and the sun-proof whitening effect of subject is
Significant effective number linearly rises, this conclusion confirms piceatannol significant sun-proof whitening function in the present invention.
The present invention can whitening, lighten the stain, achieve the effect that deep layer skin care;Ultraviolet light can be absorbed strongly simultaneously, turned
Light-wave energy is moved, is achieved the purpose that effectively sun-proof.The present invention is safe and reliable, proportion rationally, be able to satisfy different crowd to health and
The demand of visual sense of beauty.Using sun-proof whitening and skin-protecting agent proposed by the present invention, lotion, moisturizing can be needed to configure into according to product
A series of skin-protection products such as cream, face cream, sleep mask.
Above the embodiment of the present invention is only that preferred embodiment is described, and is not intended to restrict the invention.
For those skilled in the art, it can still modify to the technical solution of previous embodiment, replace, improve.It is all
Without prejudice within the spirit and principles in the present invention, any modification, replacement, improvement for being made etc. should all fall into right of the present invention
Within the protection scope that claim determines.
Claims (8)
1. a kind of sun-proof whitening and skin-protecting agent, which is characterized in that the raw material including following parts by weight:
Citrus bark extract: 0.5~1.5 part, 1~10 part of piceatannol, 1~40 part of moisturizer, 0.01~2.00 part of chelating agent,
0.05~5.00 part of thickener, 0.1~30.0 part of emollient, 0.01~40.00 part of skin conditioning agent, 100 parts of water.
2. sun-proof whitening and skin-protecting agent according to claim 1, which is characterized in that the moisturizer include glycerol, glycerine,
At least one of reed fragrant plant glue, sorbierite.
3. sun-proof whitening and skin-protecting agent according to claim 1, which is characterized in that the chelating agent includes citric acid, EDTA
At least one of disodium.
4. sun-proof whitening and skin-protecting agent according to claim 1, which is characterized in that the thickener includes carbomer, poly- third
At least one of olefin(e) acid sodium, triethanolamine.
5. sun-proof whitening and skin-protecting agent according to claim 1, which is characterized in that the emollient includes that cetostearyl alcohol is poly-
At least one of ether -25, dimethyl silicone polymer, hexadecanol, mineral oil.
6. sun-proof whitening and skin-protecting agent according to claim 1, which is characterized in that the skin conditioning agent includes hyalomitome
At least one of acid, levulan.
7. sun-proof whitening and skin-protecting agent according to claim 1, which is characterized in that the citrus bark extract uses titanium dioxide
Carbon supercritical extraction technique.
8. the preparation method of -7 any sun-proof whitening and skin-protecting agent according to claim 1, which is characterized in that include the steps that
It is as follows:
Step 1: water phase pot, stirring is added in the water for having determined that parts by weight, moisturizer, chelating agent, thickener;It is heated to 80
~85 DEG C, dispersion stirs evenly, as water phase;
Step 2: the emollient for having determined that parts by weight is added in oily phase pot, 75~80 DEG C are heated to, is stirred after thawing equal
It is even, as oily phase;
Step 3: water phase and oil phase material are pumped into emulsion pot, homogeneous, stirring cooling when temperature is down to 40~45 DEG C, adds
The skin conditioning agent, citrus bark extract and piceatannol for entering to have determined that parts by weight, stir evenly, are cooled below 38
DEG C when stop stirring, as gained.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910264463.1A CN109998951A (en) | 2019-04-03 | 2019-04-03 | A kind of sun-proof whitening and skin-protecting agent and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910264463.1A CN109998951A (en) | 2019-04-03 | 2019-04-03 | A kind of sun-proof whitening and skin-protecting agent and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109998951A true CN109998951A (en) | 2019-07-12 |
Family
ID=67169593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910264463.1A Pending CN109998951A (en) | 2019-04-03 | 2019-04-03 | A kind of sun-proof whitening and skin-protecting agent and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109998951A (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012046448A (en) * | 2010-08-26 | 2012-03-08 | Maruzen Pharmaceut Co Ltd | Agent for recovery from ultraviolet damage |
JP2013151458A (en) * | 2012-01-25 | 2013-08-08 | Morinaga & Co Ltd | Glutathione production promoter |
JP2017149732A (en) * | 2017-03-30 | 2017-08-31 | 森永製菓株式会社 | Solution of plant extract containing piceatannol, and stabilization method of piceatannol comprised in solution thereof |
CN107375086A (en) * | 2017-08-10 | 2017-11-24 | 广州市金原生物科技有限公司 | A kind of whitening sun protection skin care item and preparation method thereof |
CN108619033A (en) * | 2018-07-05 | 2018-10-09 | 上海新高姿化妆品有限公司 | Whitening and skin-protecting essence and preparation method thereof with collaboration whitening effect |
-
2019
- 2019-04-03 CN CN201910264463.1A patent/CN109998951A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012046448A (en) * | 2010-08-26 | 2012-03-08 | Maruzen Pharmaceut Co Ltd | Agent for recovery from ultraviolet damage |
JP2013151458A (en) * | 2012-01-25 | 2013-08-08 | Morinaga & Co Ltd | Glutathione production promoter |
JP2017149732A (en) * | 2017-03-30 | 2017-08-31 | 森永製菓株式会社 | Solution of plant extract containing piceatannol, and stabilization method of piceatannol comprised in solution thereof |
CN107375086A (en) * | 2017-08-10 | 2017-11-24 | 广州市金原生物科技有限公司 | A kind of whitening sun protection skin care item and preparation method thereof |
CN108619033A (en) * | 2018-07-05 | 2018-10-09 | 上海新高姿化妆品有限公司 | Whitening and skin-protecting essence and preparation method thereof with collaboration whitening effect |
Non-Patent Citations (1)
Title |
---|
K. E. POLUNIN ET AL.: ""Adsorption Properties of Synthetic Piceatannol"", 《PROTECTION OF METALS》 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN110302071A (en) | Blue light protection cosmetic composition and preparation method thereof and the cosmetics for including the composition | |
CN105381007B (en) | External medicine composition, preparation with white-skinned face function and its preparation method and application | |
CN103025333A (en) | Compound, composition, and method for protecting skin from high energy visible light | |
CN110339076B (en) | Sun-screening composition with broad-spectrum light protection effect and preparation method and application thereof | |
CN112263493B (en) | Sunscreen composition, sunscreen gel containing sunscreen composition and preparation method of sunscreen gel | |
CN110946797A (en) | Abelmoschus manihot sun repair gel sleeping mask and preparation method thereof | |
CN109077952A (en) | Anti- blue light air cushion CC frost and preparation method thereof | |
CN109549893A (en) | A kind of preparation method with anti-blue light contamination and the composition repaired and essence cream and its essence cream | |
CN105560157A (en) | Novel application of Cordyceps fungus extract | |
CN106214507B (en) | A kind of chlorophyll sunlight screening skin-protecting product and preparation method thereof | |
CN109077974A (en) | One kind having the anti-sweat type all band sunlight screening skin-protecting product of waterproof | |
CN109248135A (en) | A kind of sheen highlights, the external-use skin care of concealing moisturizing combination and preparation method thereof | |
CN115300432A (en) | After-sun repair composition and preparation method and application thereof | |
CN109939020A (en) | A kind of sun-proof skin whitening, moisturizing skin conditioner and preparation method thereof | |
CN104188859B (en) | A kind of crease-resistant skin care emulsion containing natural component extract and preparation method thereof | |
CN111658587A (en) | Collagenase inhibitor composition, anti-aging water lotion and preparation method thereof | |
CN109998951A (en) | A kind of sun-proof whitening and skin-protecting agent and preparation method thereof | |
CN111450005A (en) | Beautifying and skin-brightening composition, beautifying and skin-brightening skin care product and preparation method thereof | |
CN111514075B (en) | Sunscreen composition and application thereof | |
CN107648117A (en) | A kind of whitening spot-removing skin care item and preparation method thereof | |
CN109125216A (en) | A kind of sun-proof whitening and skin-protecting agent of nti-freckle and preparation method thereof | |
CN113576935A (en) | Sunscreen repair composition and preparation method thereof | |
CN109966160A (en) | A kind of multiple radiation protection Pickering lotion and preparation method thereof containing natural products | |
CN110478273A (en) | A kind of sun-screening agent and preparation method thereof containing Paeonol | |
CN115778873B (en) | Functional component and composition for resisting aging and brightening eyes as well as preparation method and application thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190712 |