CN109925454A - A kind of soothing liver and strengthening spleen that treating non-alcohol fatty liver is dispelled rouge Chinese medicine composition - Google Patents
A kind of soothing liver and strengthening spleen that treating non-alcohol fatty liver is dispelled rouge Chinese medicine composition Download PDFInfo
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Abstract
The present invention provides a kind of soothing liver and strengthening spleen for treating non-alcohol fatty liver and dispels rouge Chinese medicine composition, which is formed by the drug matching of following portions by weight: 10~30g of radix bupleuri, 10~40g of oriental wormwood, 10~30g of honeysuckle, 10~30g of Prunella vulgaris, 10~30g of Schisandra chinensis, 10~30g of the root bark of white mulberry, 10~30g of seaweed, 10~30g of malt, 5~20g of Radix Notoginseng, 10~30g of bryozoatum.Chinese medicine composition of the invention have soothing liver and strengthening spleen, clearing away heat and eliminating dampeness, promoting blood circulation dispel rouge the effect of, clinical symptoms and sign can be effectively improved, reduce liver function and blood lipids index, and effectively prevent the disease progression of non-alcohol fatty liver (including nonalcoholic fatty liver disease).
Description
Technical field
The present invention relates to the field of Chinese medicines more particularly to a kind of soothing liver and strengthening spleen for treating non-alcohol fatty liver to dispel in rouge
Drug composition.
Background technique
Non-alcoholic fatty liver disease is generally existing in many countries as a kind of chronic liver damaging disease.Non-alcoholic
Fatty liver disease is a kind of metabolic stress hepar damnification closely related with insulin resistance and inheritance susceptible, and pathology change
Become similar to alcoholic liver disease, but patient, without excessive drinking history, spectrum of disease includes non-alcoholic simple fatty liver, non-alcohol
Property steatohepatitis and its related liver cirrhosis and hepatocellular carcinoma.
Non-alcohol fatty liver pathogenesis is extremely complex, not yet illustrates completely so far.In recent years, with society, China
Fast development that can be economic, the improvement of people's living standards, the disease incidence and recall rate of non-alcohol fatty liver present by
Year increased trend, which, which has become, seriously affects our people's physical and mental health and national economy, social development and stable master
Want one of disease.Because the disease has high illness rate, the incidence trend that becomes younger, chronic progress and the shadow that cardiovascular event occurs
The features such as ringing, so increasingly showing the importance of its clinical treatment.
Non-alcoholic fatty liver disease can belong to the scopes such as " hypochondriac pain " of Chinese medicine, " liver addiction ".This disease etiology and pathogenesis be due to
Overfeeding delicious food savoury or spleen deficiency lose fortune, pure and impure not change, and cause damp and hot interior life, and damp and hot heresy blocks channels and collaterals, makes liver-qi depression, mechanism of qi
Stasis, it is strongly fragrant in damp and hot turbid pathogenic factor hemostasis to send out in liver and gallbladder as this disease.Therefore this disease disease located in liver, belong to asthenia in origin and asthenia in superficiality, this void based on spleen,
Mark is real mainly related with the damp and hot, stagnation of the circulation of vital energy, hemostasis.Damp-heat blocking in the body, liver-qi depression, obstruction of collaterals by blood stasis are the places of its illness key.Closely
Year over numerous studies prove, drug therapy approach one of of the traditional Chinese medicine as non-alcoholic fatty liver disease, to promotion fatty liver
Reverse and to improve clinical symptoms and certain lab index be effective.
Summary of the invention
It dispels rouge Chinese traditional medicine composition the purpose of the present invention is to provide a kind of soothing liver and strengthening spleen for treating non-alcohol fatty liver
Object, which can be effectively improved clinical symptoms and sign, reduce liver function and blood lipids index, and effectively prevent non-alcohol
The disease progression of property fatty liver disease (including nonalcoholic fatty liver disease).
To solve the above problems, technical solution provided by the invention is as follows:
A kind of soothing liver and strengthening spleen that treating non-alcohol fatty liver is dispelled rouge Chinese medicine composition, the Chinese medicine composition by with
The bulk pharmaceutical chemicals compatibility of lower parts by weight forms: 10~30g of radix bupleuri, 10~40g of oriental wormwood, 10~30g of honeysuckle, Prunella vulgaris 10~
30g, 10~30g of Schisandra chinensis, 10~30g of the root bark of white mulberry, 10~30g of seaweed, 10~30g of malt, 5~20g of Radix Notoginseng, bryozoatum 10~
30g。
For the better effect obtained, the Chinese medicine composition of the invention can be preferably by the raw material of following parts by weight
Medicine compatibility forms: radix bupleuri 30g, oriental wormwood 40g, honeysuckle 30g, Prunella vulgaris 30g, Schisandra chinensis 30g, root bark of white mulberry 30g, seaweed 30g, wheat
Bud 30g, Radix Notoginseng 20g, bryozoatum 30g.
For the better effect obtained, the Chinese medicine composition of the invention can be preferably by the raw material of following parts by weight
Medicine compatibility forms: 15~25g of radix bupleuri, 15~35g of oriental wormwood, 15~25g of honeysuckle, 15~25g of Prunella vulgaris, 15~25g of Schisandra chinensis,
15~25g of the root bark of white mulberry, 15~25g of seaweed, 15~25g of malt, 10~15g of Radix Notoginseng, 15~25g of bryozoatum.
For the better effect obtained, the Chinese medicine composition of the invention can be preferably by the raw material of following parts by weight
Medicine compatibility forms: 20~25g of radix bupleuri, 15~30g of oriental wormwood, 20~25g of honeysuckle, 20~25g of Prunella vulgaris, 20~25g of Schisandra chinensis,
20~25g of the root bark of white mulberry, 20~25g of seaweed, 20~25g of malt, 10~15g of Radix Notoginseng, 15~20g of bryozoatum.
For the better effect obtained, the Chinese medicine composition of the invention can be preferably by the raw material of following parts by weight
Medicine compatibility forms: radix bupleuri 20g, oriental wormwood 20g, honeysuckle 20g, Prunella vulgaris 20g, Schisandra chinensis 20g, root bark of white mulberry 20g, seaweed 20g, wheat
Bud 20g, Radix Notoginseng 10g, bryozoatum 20g.
For the better effect obtained, the Chinese medicine composition of the invention can be preferably by the raw material of following parts by weight
Medicine compatibility forms: radix bupleuri 10g, oriental wormwood 10g, honeysuckle 10g, Prunella vulgaris 10g, Schisandra chinensis 10g, root bark of white mulberry 10g, seaweed 10g, wheat
Bud 10g, Radix Notoginseng 5g, bryozoatum 10g.
For the better effect obtained, the Chinese medicine composition of the invention can also add 20~30g of raw oyster.
For the better effect obtained, the Chinese medicine composition of the invention can also add 10~20g of curcuma zedoary.
For the better effect obtained, the Chinese medicine composition of the invention is also added with sweetener, aromatic, disintegration
Agent, the Chinese medicine composition are granule, capsule or tablet.
Above-mentioned Chinese medicine composition can be applied in treatment nonalcoholic fatty liver disease product.
Theoretical foundation of the invention is:
The dry root of radix bupleuri, umbelliferae bupleurum or radix bupleuri scorzoneraefolii, cold nature, bitter, pungent, return liver warp, gallbladder channel, are normal
Diaphoretic medicine, tool soothing liver-gallbladder dredge gas relieve stagnation, dissipate effect of fire.Saturating table expels the heat-evil, soothing liver-qi stagnation, lifting disease.Cure mainly liver depression
The stagnation of the circulation of vital energy, sternal rib pain, cold, fever, fevers and chills alternate etc..
Oriental wormwood, perennial herb or fruticuli, bitter in taste, pungent, slightly cold, returns spleen, stomach, liver and gallbladder channel.It has significant guarantor
Liver effect, to Combined hepatitis A and B vaccine, icteric hepatitis has significant curative effect.There is cholagogue, promote bile secretion, increases gallbladder in bile
The effect of acid and bilirubin discharge.It can increase heart coronary artery blood flow, improve microcirculation, and have blood pressure lowering, reducing blood lipid is anticoagulant
Blood, diuresis is antipyretic to relieving asthma, and drives away roundworm and inhibits the effect of a variety of pathogenic dermatophytes and bacterium.
Honeysuckle, nature and flavor are sweet, cold, return lung, the heart, stomach meridian.With clearing heat and detoxicating, dispelling wind and heat from the body and other effects, also there is tonifying spleen
The effect of QI invigorating, profit liver cough-relieving, relieving spasm to stop pain, mediation property of medicine, cure mainly warm disease heating, toxic-heat and blood stasis, ulcer serious case of furuncle etc..
The effect of Prunella vulgaris is renascent herb, and nature and flavor bitter, acrid, cold have improving eyesight of relieving inflammation or internal heat, removing toxic substances of clearing liver, dissipating bind, it is main
Control acute icteric hepatitis, liver diminution, red eye, swell pain, headache etc..
Schisandra chinensis is the dry mature fruit of magnoliaceae schisandra or schisandra chinensis.Its fruit contains schizandrin
And vitamin C, resin, tannin and a small amount of carbohydrate.Have and astringes the lung to stop cough, nourishes the benefits of arresting seminal emission, antidiarrheal hidroschesis.Its leaf, fruit can mention
Take aromatic oil.Kernel contains fat oil, and oil expression can make the raw material of industry, lubricating oil.Stem hide fiber is flexible, for rope.It cures mainly and holds back
Lung, nourshing kidney, promote the production of body fluid, receive sweat, arresting seminal emission, the deficiency syndrome of the lung breath with cough, thirst, spontaneous perspiration, night sweat, the thin thin, emission of internal lesion caused by overexertion and chronic diarrhea it is long
Dysentery.
The root bark of white mulberry is the dry root skin of moraceae plants mulberry, removing heat from lung and relieving asthma, inducing diuresis for removing edema.Main lung heat breathes heavily phlegm, and water drink stops lung,
Turgor asthma is anxious, oedema, tinea pedis, difficult urination.For dyspnea and cough due to lung-heat, edema swelling oliguria, appearance skin edema.
Seaweed is the drying frond of Wei Zao section plant Sargassum or sargassum fusifome；Nature and flavor: bitter, salty, cold.Return liver, stomach, kidney channel；
Performance characteristics: resolving hard lump, dissolving phlegm, Li Shui are improved and are immunized, and are used for phlegm retention oedema.
Malt is the ripening fruits of the gramineae plant barley Preparation process product dry through germination, nature and flavor sweet and neutral；Returns spleen,
Stomach meridian, Liver Channel.With promoting the circulation of qi helps digestion, the effect of spleen benefiting and stimulating the appetite, soothing the liver promoting the circulation of qi, moves back newborn dissipate-swelling.
Radix Notoginseng is the dry root and rhizome of panax araliaceae plant, and nature and flavor are sweet, slight bitter, and temperature returns liver, stomach meridian.It cures mainly and coughs up
Blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain and tumbling and swelling.
Bryozoatum, usually by aluminium, potassium, sodium silicate institute at that is, with SiO2Similar glass group as main component
At mineral, nature and flavor are salty, cold, return lung, kidney, liver and large intestine channel, have clearing lung-heat fire, change old phlegm, softening hard masses and treating stranguria effect.For
Cough with lung heat, the thick color Huang of phlegm, hemoptysis, bronchitis and scrofula etc..
Raw oyster, nature and flavor are salty, slightly cold；Return liver, gallbladder, kidney channel.It is transquilization with heavy material, checking exuberance of yang and tonifying yin, resolving hard lump, astringency inducing.
For insomnia of palpitating with fear, dizziness and tinnitus, scrofula subcutaneous nodule levies lump in the abdomen lump in the abdomen, spontaneous sweating, and band, stomachache and sour regurgitation are collapsed in spermatorrhea.Calcined oyster shell convergence
Astringent method.For spontaneous sweating, band is collapsed in spermatorrhea, acid regurgitation of having a stomachache.
Curcuma zedoary is the rhizome of zingiberaceous plant curcuma zedoary, Guangxi zedoary and RADIX CURCUMAE.Meridian distribution of property and flavor is pungent, bitter, and temperature returns liver, spleen
Through.Cure mainly qi and blood stagnation, trusted subordinate's distending pain, abdominal mass, accumulation, place food do not disappear, women's blood stasis and traumatic injury are had a pain.Curcuma zedoary master
It administers the industry gas blood-breaking, clearing stagnation and killing pain has antitumor action.
The beneficial effect of the present invention compared with the existing technology is: the Chinese medicine composition is by medicinal radix bupleuri, oriental wormwood etc. to dredge
Liver and qi, clearing heat and expelling damp；Medicinal honeysuckle, Prunella vulgaris, Schisandra chinensis, root bark of white mulberry etc. are with clearing heat and detoxicating dampness elimination；Medicinal Algae, wheat
Bud, bryozoatum etc. are dispelled rouge with strengthening the spleen and stomach, dissolving phlegm；Medicinal Radix Notoginseng is with blood circulation promoting and dispersing pathogen accumulation；All formulas are matched can soothing liver and strengthening spleen, heat-clearing
Wet, rouge of dispelling of invigorating blood circulation can be effectively improved clinical symptoms and sign, reduce liver function and blood lipids index, and effectively prevent non-alcohol
The disease progression of property fatty liver disease (including nonalcoholic fatty liver disease).
Specific embodiment
Soothing liver and strengthening spleen of the invention is dispelled in rouge Chinese medicine composition with radix bupleuri, oriental wormwood as monarch, with dispersing stagnated hepatoqi, clearing heat and expelling damp,
Honeysuckle, Prunella vulgaris, Schisandra chinensis, the root bark of white mulberry are minister, with clearing heat and detoxicating dampness elimination.Assistant with seaweed, malt, bryozoatum, with invigorating the spleen and
Stomach, dissolving phlegm are dispelled rouge, and Radix Notoginseng is to make medicine, blood circulation promoting and dispersing pathogen accumulation.All formulas are matched, altogether long memorial liver spleen, clearing away heat and eliminating dampeness, promoting blood circulation dispel rouge the benefits of.
The present invention will now be described in detail with reference to examples.
Embodiment one
A kind of soothing liver and strengthening spleen for treating non-alcohol fatty liver of the present embodiment is dispelled rouge Chinese medicine composition, by effectively at
Divide and formed with the acceptable auxiliary material of medicine, the Chinese medicine composition is formed by the bulk pharmaceutical chemicals compatibility of following parts by weight:
Radix bupleuri 10g, oriental wormwood 10g, honeysuckle 10g, Prunella vulgaris 10g, Schisandra chinensis 10g, root bark of white mulberry 10g, seaweed 10g, malt
10g, Radix Notoginseng 5g, bryozoatum 10g.
A kind of above-mentioned soothing liver and strengthening spleen for treating non-alcohol fatty liver is dispelled rouge Chinese medicine composition, effective component by
Following methods prepare:
1) bulk pharmaceutical chemicals, are weighed according to the ratio, are put it into casserole, the dipped powder 3cm of clear water are added, and impregnate 15min；
2), first the bulk pharmaceutical chemicals being immersed in casserole clear water are boiled with high heat, are changed to be cooked by slow fire 20min later,
It is spare after leaching decocting liquid；
3) step 2), is filtered into remaining filter residue successively according to the operating method of step 1) and step 2), is carried out again
Processing, filters to take decocting liquid, spare；
4), the decocting liquid that will be obtained in step 2) and step 3) mixes concentration, and stirs evenly, and it is molten to form Chinese medicine composition
Liquid formulation.
Above-mentioned Chinese medicine composition can also add the conventional addition pharmaceutically such as sweetener, aromatic, disintegrating agent, adhesive
Agent and auxiliary material improve patient to the capacity of the Chinese medicine composition taste, it is more preferable in target position to facilitate the Chinese medicine composition
Performance drug effect, the Chinese medicine composition can be made for granule, capsule or tablet.The Chinese medicine composition passes through soothing the liver
Invigorating the spleen, clearing away heat and eliminating dampeness, promoting blood circulation dispel rouge the effect of reach treatment non-alcohol fatty liver (including non-alcoholic fatty liver
It is scorching) purpose.
Embodiment two
A kind of soothing liver and strengthening spleen for treating non-alcohol fatty liver of the present embodiment is dispelled rouge Chinese medicine composition, by effectively at
Divide and formed with the acceptable auxiliary material of medicine, the Chinese medicine composition is formed by the bulk pharmaceutical chemicals compatibility of following parts by weight:
Radix bupleuri 20g, oriental wormwood 20g, honeysuckle 20g, Prunella vulgaris 20g, Schisandra chinensis 20g, root bark of white mulberry 20g, seaweed 20g, malt
20g, Radix Notoginseng 10g, bryozoatum 20g.
A kind of above-mentioned soothing liver and strengthening spleen for treating non-alcohol fatty liver is dispelled rouge Chinese medicine composition, effective component
Preparation method is identical as the preparation method of embodiment one.
Above-mentioned Chinese medicine composition can also add the conventional additives and auxiliary material pharmaceutically received, can be by the Chinese medicine group
It closes object and is made for granule, capsule or tablet.The Chinese medicine composition is dispelled the function of rouge by soothing liver and strengthening spleen, clearing away heat and eliminating dampeness, promoting blood circulation
Effect achievees the purpose that treat non-alcohol fatty liver (including nonalcoholic fatty liver disease).
Embodiment three
The present embodiment is preferred embodiment, and a kind of soothing liver and strengthening spleen for treating non-alcohol fatty liver of the present embodiment is dispelled
Rouge Chinese medicine composition is made of effective component and the acceptable auxiliary material of medicine, and the Chinese medicine composition is by following parts by weight
Bulk pharmaceutical chemicals compatibility forms:
Radix bupleuri 30g, oriental wormwood 40g, honeysuckle 30g, Prunella vulgaris 30g, Schisandra chinensis 30g, root bark of white mulberry 30g, seaweed 30g, malt
30g, Radix Notoginseng 20g, bryozoatum 30g.
A kind of above-mentioned soothing liver and strengthening spleen for treating non-alcohol fatty liver is dispelled rouge Chinese medicine composition, effective component
Preparation method is identical as the preparation method of embodiment one.
Above-mentioned Chinese medicine composition can also add the conventional additives and auxiliary material pharmaceutically received, can be by the Chinese medicine group
It closes object and is made for granule, capsule or tablet.The Chinese medicine composition is dispelled the function of rouge by soothing liver and strengthening spleen, clearing away heat and eliminating dampeness, promoting blood circulation
Effect achievees the purpose that treat non-alcohol fatty liver (including nonalcoholic fatty liver disease).
Example IV
A kind of soothing liver and strengthening spleen for treating non-alcohol fatty liver of the present embodiment is dispelled rouge Chinese medicine composition, by effectively at
Divide and formed with the acceptable auxiliary material of medicine, the Chinese medicine composition is formed by the bulk pharmaceutical chemicals compatibility of following parts by weight:
Radix bupleuri 30g, oriental wormwood 40g, honeysuckle 30g, Prunella vulgaris 30g, Schisandra chinensis 30g, root bark of white mulberry 30g, seaweed 30g, malt
30g, Radix Notoginseng 20g, bryozoatum 30g, raw oyster 30g, curcuma zedoary 20g.
A kind of above-mentioned soothing liver and strengthening spleen for treating non-alcohol fatty liver is dispelled rouge Chinese medicine composition, effective component
Preparation method is identical as the preparation method of embodiment one.
Addition has resolving hard lump, the raw oyster of checking exuberance of yang and tonifying yin in the square foundation of embodiment three, and has promoting blood circulationization
The curcuma zedoary of the stasis of blood, the effect of further enhancing activating microcirculation and removing stasis medicinal, soothing liver and strengthening spleen, to improve the treatment of the traditional chinese medicine composition of the invention
Effect；Above-mentioned Chinese medicine composition can also add the conventional additives and auxiliary material pharmaceutically received, can be by the Chinese medicine composition
It is made for granule, capsule or tablet.The Chinese medicine composition by soothing liver and strengthening spleen, clearing away heat and eliminating dampeness, promoting blood circulation dispel rouge the effect of reach
To the purpose for the treatment of non-alcohol fatty liver (including nonalcoholic fatty liver disease).
The soothing liver and strengthening spleen that the present invention treats non-alcohol fatty liver is dispelled the therapeutic effect of rouge Chinese medicine composition, Ke Yitong
Crossing following clinical cases and observing further is confirmed.
One, case selection:
Patients with nonalcoholic fatty liver disease 200 is selected, the age 16~65 years old, is numbered according to consultation time, uses random number
Word table method is classified as treatment group and control group.Wherein, male 107, female 93, treatment group 100, control group 100, the age
In 16 years old or more person.
Two, case is included in standard:
(1) it is less than 140g/ weeks (women < 70g/ weeks) without drink history or equivalent amount of alcohol of drinking；
(2) virus hepatitis, drug-induced liver disease, total parenteral nutrition, hepatolenticular degeneration, autoimmune liver disease except
Etc. the specified disease that can lead to fatty liver；
(3) Hepatic biopsy changes the pathological diagnosis standard of suitable fat hepatopathy.
(4) Informed choice letter of consent voluntarily is filled in as observation object.
Three, curative effect index:
(1) clinical symptoms；
(2) liver function index: serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), paddy ammonia
Acyl transpeptidase (GGT)；
(3) blood lipids index: serum triglyceride (TG), total cholesterol (TC)；
(4) Body mass index (BMI)；
(5) liver ultrasound diagnosis.It is respectively looked into 1 time before inspection item treatment, after treatment；Biochemical indicator is complete with Olympus2700 type
Automatic biochemical analyzer detection.
Four, treatment method:
The patient for the treatment of group is daily daily 1 dose of medical fluid made from Chinese medicine composition of the invention, point 2 clothes, and
Daily Essentiale N/Essentiale Forte N capsule, 2 tablets/time, 3 times/day, the course for the treatment of is 12 weeks；The sufferer of control group daily Essentiale N/Essentiale Forte N capsule, 2
Tablet/time, 3 times/day, the course for the treatment of is 24 weeks, and the sufferer of control group does not take solution made from Chinese medicine composition of the invention.
Five, efficacy assessment standard:
Referring to relevant criterion in " new Chinese medicine guideline of clinical investigations ".
Cure: symptom, sign disappear, and laboratory, imageological examination are completely normal.
Effective: symptom, sign are substantially reduced earlier above, and liver function is normal, and blood lipids index decline meets any one person: under TC
> 20% drops, and TG declines > 30%, and imageological examination liver morphology and essence are obviously improved earlier above.
Effective: symptom, sign mitigate, and liver function improves earlier above, and rate and blood-lipid decreased meets any one person: TC decline >=
10%, TG decline >=20%, imageological examination liver morphology and essence are opposite earlier above to be improved.
It is invalid: not reach standard described above.
Six, interpretation of result:
(1) treatment group's total effective rate 91.5%, control group total effective rate 70.8%.Two groups of total effective rates compare, treatment group
Curative effect is better than control group, and difference has statistical significance (P < 0.01).
(2) after the two groups of sufferer treatments for the treatment of group and control group, liver function index is below before treatment (P < 0.01).Treatment group
Improvement situation after ALT, AST, GGT treatment is better than control group, and difference is statistically significant (P < 0.01).
(3) after the treatment, before blood lipid, BMI improve situation better than treatment, difference has statistical significance (P to treatment group's sufferer
<0.01).The pretherapy and post-treatment no significant difference of control group (P > 0.05).
(4) treatment group's sufferer after the treatment, can be effectively improved clinical symptoms and sign, reduction liver function and blood lipid refer to
Mark, and effectively prevent non-alcohol fatty liver (including nonalcoholic fatty liver disease) sb.'s illness took a turn for the worse.
Soothing liver and strengthening spleen of the invention dispels rouge Chinese medicine composition through the clinical verification in embodiment, radix bupleuri dispersing stagnated hepatoqi, landing
The effect of low liver function and blood lipid；Honeysuckle, which serves, invigorates the spleen and benefits qi, is clearing heat and detoxicating；Prunella vulgaris have resolving hard lump resolving sputum,
The effect of clearing heat and detoxicating dampness elimination；The root bark of white mulberry has the function of reducing blood lipid；There is Schisandra chinensis clearing heat and promoting diuresis, antiviral reduce to turn
The effect of adnosine deaminase；Oriental wormwood has heat-clearing and dampness-resolving, reduces serum bilirubin and mitigates swelling of liver cell, rouge becomes and necrosis
Effect；Seaweed can enhance cellular immunity, improve liver function；Radix Notoginseng has the function of activating microcirculation and removing stasis medicinal；Malt and bryozoatum tool
There is strengthening the spleen and stomach, reduce blood lipid and liver function.All formulas are matched can soothing liver and strengthening spleen, clearing away heat and eliminating dampeness, promoting blood circulation dispel rouge, Ke Yiyou
Effect improves clinical symptoms and sign, reduces liver function and blood lipids index, and it is (including non-to effectively prevent non-alcohol fatty liver
Alcoholic fatty liver is scorching) disease progression.
During clinical observation, does not find that drug of the present invention has any undesirable toxic side effect, show in of the invention
Drug composition is safe and effective.
In conclusion although the present invention has been disclosed above in the preferred embodiment, but above preferred embodiment is not to limit
The system present invention, those skilled in the art can make various changes and profit without departing from the spirit and scope of the present invention
Decorations, therefore protection scope of the present invention subjects to the scope of the claims.
Claims (10)
- A kind of rouge Chinese medicine composition 1. soothing liver and strengthening spleen for treating non-alcohol fatty liver is dispelled, which is characterized in that the Chinese medicine Composition is formed by the bulk pharmaceutical chemicals compatibility of following parts by weight: 10~30g of radix bupleuri, 10~40g of oriental wormwood, 10~30g of honeysuckle, summer 10~30g of withered grass, 10~30g of Schisandra chinensis, 10~30g of the root bark of white mulberry, 10~30g of seaweed, 10~30g of malt, 5~20g of Radix Notoginseng, sea 10~30g of float stone.
- 2. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition is by following parts by weight Bulk pharmaceutical chemicals compatibility forms: radix bupleuri 30g, oriental wormwood 40g, honeysuckle 30g, Prunella vulgaris 30g, Schisandra chinensis 30g, root bark of white mulberry 30g, seaweed 30g, malt 30g, Radix Notoginseng 20g, bryozoatum 30g.
- 3. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition is by following parts by weight Bulk pharmaceutical chemicals compatibility forms: 15~25g of radix bupleuri, 15~35g of oriental wormwood, 15~25g of honeysuckle, 15~25g of Prunella vulgaris, Schisandra chinensis 15~ 25g, 15~25g of the root bark of white mulberry, 15~25g of seaweed, 15~25g of malt, 10~15g of Radix Notoginseng, 15~25g of bryozoatum.
- 4. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition is by following parts by weight Bulk pharmaceutical chemicals compatibility forms: 20~25g of radix bupleuri, 15~30g of oriental wormwood, 20~25g of honeysuckle, 20~25g of Prunella vulgaris, Schisandra chinensis 20~ 25g, 20~25g of the root bark of white mulberry, 20~25g of seaweed, 20~25g of malt, 10~15g of Radix Notoginseng, 15~20g of bryozoatum.
- 5. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition is by following parts by weight Bulk pharmaceutical chemicals compatibility forms: radix bupleuri 20g, oriental wormwood 20g, honeysuckle 20g, Prunella vulgaris 20g, Schisandra chinensis 20g, root bark of white mulberry 20g, seaweed 20g, malt 20g, Radix Notoginseng 10g, bryozoatum 20g.
- 6. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition is by following parts by weight Bulk pharmaceutical chemicals compatibility forms: radix bupleuri 10g, oriental wormwood 10g, honeysuckle 10g, Prunella vulgaris 10g, Schisandra chinensis 10g, root bark of white mulberry 10g, seaweed 10g, malt 10g, Radix Notoginseng 5g, bryozoatum 10g.
- 7. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition further include raw oyster 20~ 30g。
- 8. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition further include curcuma zedoary 10~ 20g。
- 9. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition be also added with sweetener, Aromatic, disintegrating agent, the Chinese medicine composition are granule, capsule or tablet.
- 10. application of the described in any item Chinese medicine compositions of claim 1-9 in treatment nonalcoholic fatty liver disease product.
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Citations (3)
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|---|---|---|---|---|
| CN1380080A (en) * | 2002-04-25 | 2002-11-20 | 刘桂英 | Medicine for curing fatty liver |
| CN1824091A (en) * | 2005-12-13 | 2006-08-30 | 中山市中医院 | Chinese medicinal preparation for treating fattly liver |
| CN106074918A (en) * | 2016-07-04 | 2016-11-09 | 深圳市中医院 | A kind of soothing the liver fat Chinese medicine composition that disappears treating non-alcohol fatty liver |
-
2017
- 2017-12-19 CN CN201711376595.0A patent/CN109925454A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380080A (en) * | 2002-04-25 | 2002-11-20 | 刘桂英 | Medicine for curing fatty liver |
| CN1824091A (en) * | 2005-12-13 | 2006-08-30 | 中山市中医院 | Chinese medicinal preparation for treating fattly liver |
| CN106074918A (en) * | 2016-07-04 | 2016-11-09 | 深圳市中医院 | A kind of soothing the liver fat Chinese medicine composition that disappears treating non-alcohol fatty liver |
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| 周祺: "于志强治疗脂肪肝的经验", 《河北中医》 * |
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Application publication date: 20190625 |