CN105998831A - Traditional Chinese medicine for treating seborrheic dermatitis and preparation method thereof - Google Patents
Traditional Chinese medicine for treating seborrheic dermatitis and preparation method thereof Download PDFInfo
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- CN105998831A CN105998831A CN201610530665.2A CN201610530665A CN105998831A CN 105998831 A CN105998831 A CN 105998831A CN 201610530665 A CN201610530665 A CN 201610530665A CN 105998831 A CN105998831 A CN 105998831A
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Abstract
The invention provides a traditional Chinese medicine for treating seborrheic dermatitis and a preparation method thereof. The traditional Chinese medicine is prepared from, by weight, 5-12 parts of mint, 3-10 parts of rhizoma pinelliae, 3-10 parts of lavenders, 2-10 parts of dried tangerine or orange peels, 5-12 parts of hawthorn, 1-5 parts of borneol, 1-6 parts of wild buckwheat rhizomes, 3-10 parts of ageratum, 1-5 parts of bitter magnolia barks, 2-11 parts of white atractylodes rhizomes, 1-8 parts of Chinese toon leaves, 1-6 parts of radix semiaquilegiae, 2-3 parts of cyperus rotundus, 1-8 parts of radish leaves, 1-5 parts of cymbopogon flowers, 1-6 parts of ginger and 2-6 parts of loquat leaves. The traditional Chinese medicine has the excellent advantages of being fast, effective, safe, hygienic and free of toxic and side effects and making seborrheic dermatitis not relapse, and the preparation method is scientific and effective, simple and practical and suitable for large-scale promotion in the field of traditional Chinese medicines.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of for Chinese medicine treating seborrheic dermatitis and preparation method thereof.
Background technology
Seborrheic dermatitis, also known as seborrheic eczema, is to occur at sebaceous gland and enriches the one chronic papulosquamous inflammatory dermatoses at position.Primary disease is more common in adult and neonate, is apt to occur in the sebaceous gland such as head, trunk and enriches district.In recent years, Pityrosporum ovale is paid attention to the relation of seborrheic dermatitis, it is believed that it plays an important role in the morbidity of seborrheic dermatitis.Additionally, Nervous and Mental Factors, dietary habit, vitamin B group lack and be addicted to drink, the generation development on primary disease has been likely to certain impact.General and the seborrheic dermatitis of the stubbornness skin symptom that can be HIV important, has intractable strong, difficult radical cure, the easily feature of recurrence.
Although treatment seborrheic dermatitis medicine in the market has certain therapeutic effect, but but there is slow curative effect, toxic and side effects shortcoming big, easily recurrence, additionally liniment is in the majority, therapeutic effect does not digs up the roots, easily contact with external environment, there is safety and Health hidden danger, therefore invent a kind of novel being necessary for Chinese medicine treating seborrheic dermatitis and preparation method thereof.
Summary of the invention
For the deficiencies in the prior art, the invention provides a kind of for Chinese medicine treating seborrheic dermatitis and preparation method thereof, have the most effectively, have no side effect, the good characteristics not recurred.
For realizing object above, the present invention is achieved by the following technical programs:
The invention provides a kind of Chinese medicine for treating seborrheic dermatitis, the raw material of following weight portion be prepared from: Herba Menthae 5-12 part, Fructus Aurantii 3-10 part, lavandula angustifolia 3-10 part, Pericarpium Citri Reticulatae 2-10 part, Fructus Crataegi 5-12 part, Borneolum Syntheticum 1-5 part, Rhizoma Fagopyri Dibotryis 1-6 part, Herba Pogostemonis 3-10 part, Cortex Magnoliae Officinalis hardship 1-5 part, Rhizoma Atractylodis Macrocephalae 2-11 part, Folium toonae sinensis 1-8 part, Radix Semiaquilegiae 1-6 part, Rhizoma Cyperi 2-3 part, radish 1-8 part, Herba Cymbopogonis Citrari 1-5 part, Herba Micromeriae Biflorae 1-6 part, Folium Eriobotryae 2-6 part;
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 30-50min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) weigh Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae by weight, raw material B must be mixed, immerse and ethanol solution soaks 3-5h, then big fire heating extraction 1-2h, then slow fire heating extraction 1-2h, filter to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 8-10 times, decocts 3-4h, filter, obtain filtering residue and extracting solution after soaking 5-6h;In filtering residue, addition is the distilled water of filtering residue 6-8 times again, decocts 2-3h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4-6 times, heated and boiled 1-2h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation, except water, makes tablet medicine.
Preferably, the raw material of following weight portion it is prepared from: Herba Menthae 6-10 part, Fructus Aurantii 4-8 part, lavandula angustifolia 4-9 part, Pericarpium Citri Reticulatae 3-8 part, Fructus Crataegi 5-12 part, Borneolum Syntheticum 2-4 part, Rhizoma Fagopyri Dibotryis 2-5 part, Herba Pogostemonis 4-8 part, Cortex Magnoliae Officinalis hardship 2-4 part, Rhizoma Atractylodis Macrocephalae 4-10 part, Folium toonae sinensis 2-6 part, Radix Semiaquilegiae 2-5 part, Rhizoma Cyperi 2-3 part, radish 2-7 part, Herba Cymbopogonis Citrari 2-4 part, Herba Micromeriae Biflorae 2-4 part, Folium Eriobotryae 2-6 part.
Preferably, the raw material of following weight portion it is prepared from: Herba Menthae 8 parts, Fructus Aurantii 4 parts, lavandula angustifolia 5 parts, Pericarpium Citri Reticulatae 4 parts, Fructus Crataegi 5 parts, Borneolum Syntheticum 3 parts, Rhizoma Fagopyri Dibotryis 2 parts, Herba Pogostemonis 6 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 6 parts, Folium toonae sinensis 3 parts, Radix Semiaquilegiae 2 parts, Rhizoma Cyperi 3 parts, radish 3 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 3 parts, Folium Eriobotryae 3 parts.
Preferably, the raw material of following weight portion it is prepared from: Herba Menthae 9 parts, Fructus Aurantii 5 parts, lavandula angustifolia 6 parts, Pericarpium Citri Reticulatae 5 parts, Fructus Crataegi 6 parts, Borneolum Syntheticum 2 parts, Rhizoma Fagopyri Dibotryis 1 part, Herba Pogostemonis 6 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 7 parts, Folium toonae sinensis 1 part, Radix Semiaquilegiae 3 parts, Rhizoma Cyperi 2 parts, radish 3 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 4 parts, Folium Eriobotryae 3 parts.
Preferably, in described preparation method step (3), the relative concentration of ethanol solution is 80%, measures the 5-6 times amount into mixing raw material B.
Preferably, the described tablet medicine average diameter in preparation method step (4) is 5-8mm.
In the present invention, effect of each raw material is as follows:
Herba Menthae: dispelling wind and heat pathogens, the clear profit head, sore-throat relieving rash, soothing the liver circulation of qi promoting.Affection due to external wind and heat, headache, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria, epidemic febrile disease is from the beginning of, rubella pruritus, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest.
Fructus Aurantii: cure mainly chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight, proctoptosis, uterine prolapse after dysentery.
Lavandula angustifolia: treatment regulation hormonal system, menstrual pain, pass knot pain, melancholia, dyspepsia, fat-reducing body shaping before and after the physiology phase.
Pericarpium Citri Reticulatae: for diseases such as distension and fullness of the chest and abdomen.Pericarpium Citri tangerinae is pungent dissipates logical temperature, fragrant odour, is longer than and regulates the flow of vital energy, and can enter spleen lung, therefore can go scattered sluggishness of lung-QI, again can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, gather around stagnant, chest and diaphragm feeling of fullness and the disease such as stagnation of QI in spleen and stomach, distension and fullness in the abdomen for lung qi.Often apply with the compatibility such as the Radix Aucklandiae, Fructus Aurantii.
Fructus Crataegi: haw taste acidity temperature, QI and blood also walks, blood stasis dispelling and do not hinder fresh blood, the stagnant gas of row and do not hinder healthy energy, be applied to meat stagnation card, dysentery stomachache, colicky, the stasis of blood stagnant stomachache chest pain, lochiorrhea, dysmenorrhea, spit blood, have blood in stool.Modern alone this product preparation for treating cardiovascular disease, bacillary dysentery etc., all have good therapeutic effect.
Borneolum Syntheticum: pungent, bitter, is slightly cold;GUIXIN, spleen, lung meridian;For epidemic febrile disease unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm, coma, convulsion are fainted, syncope etc..
Rhizoma Fagopyri Dibotryis: sweet, puckery, micro-hardship, cool;Return lung, Liver Channel;Heat-clearing and toxic substances removing, eliminating carbuncle sore-throat relieving: cough vomiting bloody pus, laryngopharynx swelling and pain, cough due to lung-heat etc. for lung abscess;Expelling wind and removing dampness: for rheumatic arthralgia, rheumatism muscles and bones is ached, brothers' articular instability etc..
Herba Pogostemonis: eliminating turbid pathogen with aromatics, and middle preventing or arresting vomiting, deliver expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is vomitted, heat-damp in summer exterior syndrome, and hygropyrexia, from the beginning of, asthenia of generating heat, uncomfortable in chest is not relaxed, and cold-damp closes summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Cortex Magnoliae Officinalis is bitter: acrid in the mouth, warm in nature;Circulation of qi promoting removing food stagnancy, dampness is removed full, lowering the adverse QI to relieve asthma, cures mainly stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the vomiting and diarrhoea of gastral cavity painful abdominal mass, and expectorant heap soil or fertilizer over and around the roots QI rising in reverse order, fullness in the chest is breathed with cough.
The Rhizoma Atractylodis Macrocephalae: be used as medicine with rhizome.Drying damp and strengthening spleen, insufficiency of the spleen lack of appetite, dyspepsia, chronic diarrhea, edema, hidroschesis, antiabortive.
Folium toonae sinensis: bitter in the mouth is flat;Leaf contains carotene and vitamin B, C, stomach invigorating, hemostasis, antiinflammatory, parasite killing, administration's removing dampness of dispelling, removing toxic substances, parasite killing, main heat-damp in summer damaging the spleen and stomach, nausea and vomiting, inappetence, has loose bowels, dysentery swollen ulcer drug.
Radix Semiaquilegiae: sweet, bitter, cold;Return liver, stomach warp;Heat-clearing and toxic substances removing: for furuncle furuncle and phyma etc., also can mash external application by this product.
Rhizoma Cyperi: bitter, cold.Return lung, liver, heart channel;Removing toxic substances and promoting subsidence of swelling: swell and ache for laryngopharynx swelling and pain, skin infection;Relieving cough and resolving phlegm: for cough with copious phlegm, lung-heat cough with asthma, Huang of coughing up phlegm is thick.
Radish: Folium Raphani has and helps digestion, and regulates the flow of vital energy, reduces phlegm, cough-relieving, removing heat from the lung and relieving sorethroat, effect of dissipating blood stasis for subsidence of swelling.Cure mainly stagnation of QI due to dyspepsia, gastral cavity abdomen feeling of fullness, acid regurgitation, singultus, have loose bowels, dysentery, laryngopharynx swelling and pain, expectoration, hoarseness, the diseases such as female breast swells and ache, galactostasis, external treatment damage congestive edema.
Herba Cymbopogonis Citrari: sweet in the mouth, micro-hardship, temperature;Warming middle-JIAO for easing the stomach, main trusted subordinate's cold type of pain, nausea and vomiting.
Herba Micromeriae Biflorae: acrid in the mouth, temperature;Warming middle-JIAO, regulates the flow of vital energy, pain relieving, control tell inverse, dysphagic, stomachache, stomachache, colic of cold type pain, dry spleen warming the stomach, enter diet, the alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, treat nine kinds of gastric qi pain, the cold pain in face, chest and diaphragm flatulence, tripe abdomen cold type of pain, vomiting is nauseating, dysphagic regurgitation of food from the stomach.
Folium Eriobotryae: cold nature, bitter in the mouth is pungent.Return lung, stomach warp.For cough due to lung-heat, cough due to pathogenic wind-heat, deficiency of the lung chronic cough.For gastropyretic vomiting, singultus;For cough due to lung-heat, cough due to pathogenic wind-heat, deficiency of the lung chronic cough.
The method have the benefit that
The present invention, by described each material medicine scientific compatibility, has the most effectively, has no side effect, the good characteristics not recurred, and processing technique is simple, and production cost is low, efficiently controlling seborrheic dermatitis, bring conveniently to patient, the present invention is fabricated to medicinal preparation for oral administration, drug effect absorbs more preferably, the utilization ratio avoiding liniment is low, the shortcoming that there is healthy and safe hidden danger, preparation method scientific and effective, simple and practical, it is suitable in field of Chinese medicines large-scale promotion.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with embodiments of the invention, the technical scheme in the embodiment of the present invention is clearly and completely described.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, broadly fall into the scope of protection of the invention.
Embodiment
1
:
A kind of Chinese medicine for treating seborrheic dermatitis, is prepared from by the raw material of following weight portion: Herba Menthae 5 parts, Fructus Aurantii 3 parts, lavandula angustifolia 3 parts, Pericarpium Citri Reticulatae 2 parts, Fructus Crataegi 5 parts, Borneolum Syntheticum 1 part, Rhizoma Fagopyri Dibotryis 1 part, Herba Pogostemonis 3 parts, bitter 1 part of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 2 parts, Folium toonae sinensis 1 part, Radix Semiaquilegiae 1 part, Rhizoma Cyperi 2 parts, radish 1 part, 1 part of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 1 part, Folium Eriobotryae 2 parts.
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 40min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae are weighed by weight, raw material B must be mixed, immersing relative concentration is 80%, amount soaks 3h in the ethanol solution for 5 times amount of mixing raw material B, then big fire heating extraction 1h, slow fire heating extraction 1h again, filters to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 8 times, decocts 3h, filter, obtain filtering residue and extracting solution after soaking 5h;In filtering residue, addition is the distilled water of filtering residue 6 times again, decocts 2h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4 times, heated and boiled 1h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation is except water, and making average diameter is 5mm tablet medicine.
Embodiment
2
:
A kind of Chinese medicine for treating seborrheic dermatitis, is prepared from by the raw material of following weight portion: Herba Menthae 6 parts, Fructus Aurantii 4 parts, lavandula angustifolia 4 parts, Pericarpium Citri Reticulatae 3 parts, Fructus Crataegi 5 parts, Borneolum Syntheticum 2 parts, Rhizoma Fagopyri Dibotryis 2 parts, Herba Pogostemonis 4 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 4 parts, Folium toonae sinensis 2 parts, Radix Semiaquilegiae 2 parts, Rhizoma Cyperi 2 parts, radish 2 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 2 parts, Folium Eriobotryae 6 parts.
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 40min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae are weighed by weight, raw material B must be mixed, immersing relative concentration is 80%, amount soaks 4h in the ethanol solution for 6 times amount of mixing raw material B, then big fire heating extraction 2h, slow fire heating extraction 2h again, filters to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 10 times, decocts 4h, filter, obtain filtering residue and extracting solution after soaking 6h;In filtering residue, addition is the distilled water of filtering residue 8 times again, decocts 3h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 5 times, heated and boiled 2h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation is except water, and making average diameter is 6mm tablet medicine.
Embodiment
3
:
A kind of Chinese medicine for treating seborrheic dermatitis, is prepared from by the raw material of following weight portion: Herba Menthae 6 parts, Fructus Aurantii 4 parts, lavandula angustifolia 4 parts, Pericarpium Citri Reticulatae 3 parts, Fructus Crataegi 5 parts, Borneolum Syntheticum 2 parts, Rhizoma Fagopyri Dibotryis 2 parts, Herba Pogostemonis 4 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 4 parts, Folium toonae sinensis 2 parts, Radix Semiaquilegiae 2 parts, Rhizoma Cyperi 2 parts, radish 2 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 2 parts, Folium Eriobotryae 2 parts.
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 30min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae are weighed by weight, raw material B must be mixed, immersing relative concentration is 80%, amount soaks 4h in the ethanol solution for 5 times amount of mixing raw material B, then big fire heating extraction 1h, slow fire heating extraction 1h again, filters to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 9 times, decocts 3h, filter, obtain filtering residue and extracting solution after soaking 5h;In filtering residue, addition is the distilled water of filtering residue 6 times again, decocts 2h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4 times, heated and boiled 2h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation is except water, and making average diameter is 8mm tablet medicine.
Embodiment
4
:
A kind of Chinese medicine for treating seborrheic dermatitis, is prepared from by the raw material of following weight portion: Herba Menthae 8 parts, Fructus Aurantii 4 parts, lavandula angustifolia 5 parts, Pericarpium Citri Reticulatae 4 parts, Fructus Crataegi 5 parts, Borneolum Syntheticum 3 parts, Rhizoma Fagopyri Dibotryis 2 parts, Herba Pogostemonis 6 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 6 parts, Folium toonae sinensis 3 parts, Radix Semiaquilegiae 2 parts, Rhizoma Cyperi 3 parts, radish 3 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 3 parts, Folium Eriobotryae 3 parts.
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 50min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae are weighed by weight, raw material B must be mixed, immersing relative concentration is 80%, amount soaks 5h in the ethanol solution for 6 times amount of mixing raw material B, then big fire heating extraction 2h, slow fire heating extraction 2h again, filters to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 10 times, decocts 4h, filter, obtain filtering residue and extracting solution after soaking 6h;In filtering residue, addition is the distilled water of filtering residue 6 times again, decocts 3h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4 times, heated and boiled 2h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation is except water, and making average diameter is 8mm tablet medicine.
Embodiment
5
:
A kind of Chinese medicine for treating seborrheic dermatitis, is prepared from by the raw material of following weight portion: Herba Menthae 9 parts, Fructus Aurantii 5 parts, lavandula angustifolia 6 parts, Pericarpium Citri Reticulatae 5 parts, Fructus Crataegi 6 parts, Borneolum Syntheticum 2 parts, Rhizoma Fagopyri Dibotryis 1 part, Herba Pogostemonis 6 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 7 parts, Folium toonae sinensis 1 part, Radix Semiaquilegiae 3 parts, Rhizoma Cyperi 2 parts, radish 3 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 4 parts, Folium Eriobotryae 3 parts, Folium Eriobotryae 3 parts.
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 50min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae are weighed by weight, raw material B must be mixed, immersing relative concentration is 80%, amount soaks 5h in the ethanol solution for 6 times amount of mixing raw material B, then big fire heating extraction 2h, slow fire heating extraction 2h again, filters to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 10 times, decocts 3h, filter, obtain filtering residue and extracting solution after soaking 5h;In filtering residue, addition is the distilled water of filtering residue 8 times again, decocts 2h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4 times, heated and boiled 1h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation is except water, and making average diameter is 5mm tablet medicine.
Embodiment
6
:
A kind of Chinese medicine for treating seborrheic dermatitis, is prepared from by the raw material of following weight portion: Herba Menthae 5 parts, Fructus Aurantii 3 parts, lavandula angustifolia 3 parts, Pericarpium Citri Reticulatae 2 parts, Fructus Crataegi 5 parts, Borneolum Syntheticum 1 part, Rhizoma Fagopyri Dibotryis 1 part, Herba Pogostemonis 3 parts, bitter 1 part of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 2 parts, Folium toonae sinensis 1 part, Radix Semiaquilegiae 1 part, Rhizoma Cyperi 2 parts, radish 1 part, 1 part of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 1 part, Folium Eriobotryae 6 parts.
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 40min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae are weighed by weight, raw material B must be mixed, immersing relative concentration is 80%, amount soaks 3h in the ethanol solution for 5 times amount of mixing raw material B, then big fire heating extraction 1h, slow fire heating extraction 1h again, filters to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 8 times, decocts 3h, filter, obtain filtering residue and extracting solution after soaking 5h;In filtering residue, addition is the distilled water of filtering residue 6 times again, decocts 2h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4 times, heated and boiled 1h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation is except water, and making average diameter is 5mm tablet medicine.
Embodiment
7
:
A kind of Chinese medicine for treating seborrheic dermatitis, is prepared from by the raw material of following weight portion: Herba Menthae 12 parts, Fructus Aurantii 10 parts, lavandula angustifolia 10 parts, Pericarpium Citri Reticulatae 10 parts, Fructus Crataegi 12 parts, Borneolum Syntheticum 5 parts, Rhizoma Fagopyri Dibotryis 6 parts, Herba Pogostemonis 10 parts, bitter 5 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 11 parts, Folium toonae sinensis 8 parts, Radix Semiaquilegiae 6 parts, Rhizoma Cyperi 3 parts, radish 8 parts, 5 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 6 parts, Folium Eriobotryae 6 parts.
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 40min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae are weighed by weight, raw material B must be mixed, immersing relative concentration is 80%, amount soaks 3h in the ethanol solution for 5 times amount of mixing raw material B, then big fire heating extraction 1h, slow fire heating extraction 1h again, filters to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of mixing raw material C 8 times, decocts 3h, filter, obtain filtering residue and extracting solution after soaking 5h;In filtering residue, addition is the distilled water of filtering residue 6 times again, decocts 2h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4 times, heated and boiled 1h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation is except water, and making average diameter is 5mm tablet medicine.
Toxicity test:
Take experiment mice 60, male and female half and half, body weight 16-20g, carry out acute toxicity test.Mice is randomly divided into two groups, often group 30, i.e. matched group and administration group, fasting 12 hours before experiment;
Medicine (concentration is 3.0g/ml, maximum concentration) gavage prepared by embodiments of the invention 1, gavage volume is 2ml/kg, and matched group gives normal saline, within one day, is administered once, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.
Test result indicate that: compare with matched group, after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase the most normal.The indexs such as the hair of mice, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat are all had no significant effect by Chinese medicine of the present invention, internal organs naked eyes do not find that difference change and histological indications show, after medication 16 weeks and drug withdrawal 4 weeks, Organs of Mice is all without substantially changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, after drug withdrawal, also there is no difference reaction, application safety.
Clinical case:
Case selection:
Take and derive from department of dermatologry seborrheic dermatitis patient 100 example, male 50 examples, female 50 example in February ,-2016 in May, 2015.
Therapeutic Method: this medicine oral.
The standard of curative effect evaluation:
Effective: take latter 1-2 days effective;
Effective: take latter 3-7 days effective;
Invalid: without obvious curative effects after taking 7 days.
Therapeutic outcome:
Table 1 department of dermatologry patient outcomes adds up example (%)
Patient profiles | Sum | Effective | Effectively | Invalid | Effective percentage |
Man | 50 | 44 | 4 | 2 | 96% |
Female | 50 | 46 | 3 | 1 | 98% |
According to the data of table 1, the present invention is for treating the medicine of seborrheic dermatitis, and therapeutic effect is good, instant effect, and after taking, 1 week reviewing statistics, has no adverse reaction.
Above example only in order to technical scheme to be described, is not intended to limit;Although the present invention being described in detail with reference to previous embodiment, it will be understood by those within the art that: the technical scheme described in foregoing embodiments still can be modified by it, or wherein portion of techniques feature is carried out equivalent;And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (6)
1. the Chinese medicine being used for treating seborrheic dermatitis, it is characterized in that, the raw material of following weight portion be prepared from: Herba Menthae 5-12 part, Fructus Aurantii 3-10 part, lavandula angustifolia 3-10 part, Pericarpium Citri Reticulatae 2-10 part, Fructus Crataegi 5-12 part, Borneolum Syntheticum 1-5 part, Rhizoma Fagopyri Dibotryis 1-6 part, Herba Pogostemonis 3-10 part, Cortex Magnoliae Officinalis hardship 1-5 part, Rhizoma Atractylodis Macrocephalae 2-11 part, Folium toonae sinensis 1-8 part, Radix Semiaquilegiae 1-6 part, Rhizoma Cyperi 2-3 part, radish 1-8 part, Herba Cymbopogonis Citrari 1-5 part, Herba Micromeriae Biflorae 1-6 part, Folium Eriobotryae 2-6 part;
Its preparation method is:
(1) weighing Herba Menthae, Fructus Aurantii, lavandula angustifolia, Pericarpium Citri Reticulatae, Borneolum Syntheticum, Fructus Crataegi the most by weight, obtain mixing raw material A, put into pulverizer and carry out pulverization process 30-50min, be then ground processing, the fine powder of 180 mesh crossed by the raw material after grinding, standby;
(2) weigh Rhizoma Fagopyri Dibotryis, Herba Pogostemonis, Cortex Magnoliae Officinalis hardship, the Rhizoma Atractylodis Macrocephalae, Folium toonae sinensis, Radix Semiaquilegiae by weight, raw material B must be mixed, immerse and ethanol solution soaks 3-5h, then big fire heating extraction 1-2h, then slow fire heating extraction 1-2h, filter to get filtrate, standby;
(3) weighing Rhizoma Cyperi, radish, Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae, Folium Eriobotryae by weight, must mix raw material C, put into container, addition is the distilled water of 8-10 times of mixing raw material C, decocts 3-4h, filter, obtain filtering residue and extracting solution after soaking 5-6h;In filtering residue, addition is the distilled water of filtering residue 6-8 times again, decocts 2-3h, filters, obtains filtering residue and extracting solution;Finally, addition is the distilled water of filtering residue 4-6 times, heated and boiled 1-2h, filters, obtains filtering residue and extracting solution, merge three extracting solution, standby;
(4) fine powder standby obtained by step (1)-(3), filtrate and united extraction liquid being mixed, evaporation, except water, makes tablet medicine.
2. the Chinese medicine for treating seborrheic dermatitis as claimed in claim 1, it is characterized in that, the raw material of following weight portion be prepared from: Herba Menthae 6-10 part, Fructus Aurantii 4-8 part, lavandula angustifolia 4-9 part, Pericarpium Citri Reticulatae 3-8 part, Fructus Crataegi 5-12 part, Borneolum Syntheticum 2-4 part, Rhizoma Fagopyri Dibotryis 2-5 part, Herba Pogostemonis 4-8 part, Cortex Magnoliae Officinalis hardship 2-4 part, Rhizoma Atractylodis Macrocephalae 4-10 part, Folium toonae sinensis 2-6 part, Radix Semiaquilegiae 2-5 part, Rhizoma Cyperi 2-3 part, radish 2-7 part, Herba Cymbopogonis Citrari 2-4 part, Herba Micromeriae Biflorae 2-4 part, Folium Eriobotryae 2-6 part.
3. the Chinese medicine for treating seborrheic dermatitis as claimed in claim 2, it is characterized in that, the raw material of following weight portion be prepared from: Herba Menthae 8 parts, Fructus Aurantii 4 parts, lavandula angustifolia 5 parts, Pericarpium Citri Reticulatae 4 parts, Fructus Crataegi 5 parts, Borneolum Syntheticum 3 parts, Rhizoma Fagopyri Dibotryis 2 parts, Herba Pogostemonis 6 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 6 parts, Folium toonae sinensis 3 parts, Radix Semiaquilegiae 2 parts, Rhizoma Cyperi 3 parts, radish 3 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 3 parts, Folium Eriobotryae 3 parts.
4. the Chinese medicine for treating seborrheic dermatitis as claimed in claim 2, it is characterized in that, the raw material of following weight portion be prepared from: Herba Menthae 9 parts, Fructus Aurantii 5 parts, lavandula angustifolia 6 parts, Pericarpium Citri Reticulatae 5 parts, Fructus Crataegi 6 parts, Borneolum Syntheticum 2 parts, Rhizoma Fagopyri Dibotryis 1 part, Herba Pogostemonis 6 parts, bitter 2 parts of Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae 7 parts, Folium toonae sinensis 1 part, Radix Semiaquilegiae 3 parts, Rhizoma Cyperi 2 parts, radish 3 parts, 2 parts of Herba Cymbopogonis Citrari, Herba Micromeriae Biflorae 4 parts, Folium Eriobotryae 3 parts, Folium Eriobotryae 3 parts.
5. the Chinese medicine for treating seborrheic dermatitis as claimed in claim 1, it is characterised in that in described preparation method step (3), the relative concentration of ethanol solution is 80%, measures the 5-6 times amount into mixing raw material B.
6. the Chinese medicine for treating seborrheic dermatitis as claimed in claim 1, it is characterised in that the described tablet medicine average diameter in preparation method step (4) is 5-8mm.
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