CN109908287B - Application of traditional Chinese medicine sachet in air disinfection - Google Patents

Application of traditional Chinese medicine sachet in air disinfection Download PDF

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CN109908287B
CN109908287B CN201910325695.3A CN201910325695A CN109908287B CN 109908287 B CN109908287 B CN 109908287B CN 201910325695 A CN201910325695 A CN 201910325695A CN 109908287 B CN109908287 B CN 109908287B
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chinese medicine
sachet
rhizoma
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上官贤
易斌
张青
罗丽莲
肖艳皎
韩雅慧
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Jianchangbang Pharmacy Co ltd
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Abstract

The invention relates to a traditional Chinese medicine composition for refreshing and restoring consciousness, a sachet and application thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition comprises: the traditional Chinese medicine composition comprises, by weight, 2-4 parts of nardostachys chinensis bunge, 4-6 parts of kaempferia galanga, 2-4 parts of angelica dahurica, 1-3 parts of folium artemisiae argyi, 1-3 parts of mint, 1-3 parts of asarum and 2-4 parts of storax. The traditional Chinese medicine composition also comprises 1-3 parts of rhizoma sparganii, 1-2 parts of rhizoma bolbostemmae, 2-4 parts of rhizoma bletillae and 1-3 parts of celandine. The invention also provides a traditional Chinese medicine sachet which comprises a sachet body and a traditional Chinese medicine composition filled in the sachet body. The sachet has the advantages of good refreshing effect, no side effect, convenient use, wide applicable population and air disinfection effect.

Description

Application of traditional Chinese medicine sachet in air disinfection
Technical Field
The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for refreshing and restoring consciousness, a sachet and application thereof.
Background
The sachet is a breathable bagged fabric filled with fragrant substances, on one hand, the sachet plays a decorative role by virtue of the exquisite sewing process and embroidery patterns, and on the other hand, the sachet plays a role in fumigating by virtue of spices or medicinal materials in the sachet.
The traditional Chinese medicine sachet has various formulas according to different efficacies. The common Chinese medicinal materials include rhizoma Acori Calami, folium Artemisiae Argyi, flos Magnoliae, radix Angelicae Dahuricae, radix Saposhnikoviae, herba Moslae, rhizoma Atractylodis, Atractylodis rhizoma, herba Menthae, etc. Meanwhile, according to the theory of traditional Chinese medicine, some medicines with the efficacies of tonifying qi and activating blood, tranquilizing and allaying excitement, relieving cough and reducing sputum, detoxifying and killing insects, such as codonopsis pilosula, astragalus, salvia miltiorrhiza, ligusticum wallichii and the like, are combined. The traditional Chinese medicine sachet can be widely used in clinical treatment. For example, chenhua et al have found that the use of a traditional Chinese medicine sachet consisting of agastache rugosus, rhizoma atractylodis, folium artemisiae argyi, cinnamon and kaempferia galanga can prevent the upper respiratory infection of infants (chenhua, shenmi, fang gui zhen, etc.. the effect of the fragrant balm therapy on preventing the upper respiratory infection of infants is observed [ J ]. J.J. J.Med.J., 2010,39(04): 28-30); wang Xudong et al found that a traditional Chinese medicine sachet consisting of musk, borneol, rhizoma atractylodis, agilawood, rhizoma acori graminei, cinnamon, folium artemisiae argyi, radix angelicae dahuricae, rhizoma ligustici wallichii, ligusticum, areca nut, mint leaf, clove, asarum and paris rhizome has the effect of resisting influenza A and B viruses (Wang Xudong, Xiefei, Gaoying, Studies on experiments on anti-influenza viruses [ J ] of China traditional Chinese medicine journal, 2010(06): 927-.
In modern society, with the increase of living pressure, students and office workers are easy to fatigue and sleepy due to overlong mental labor time, and have poor consequences such as unclear thinking, disordered thinking, low working efficiency and the like. People usually refresh by drinking drinks such as coffee, strong tea and the like, but the drinks are easy to cause dependence and can cause adverse symptoms such as insomnia and the like. In this situation, researchers have attempted to improve the ingredients of sachet drugs to achieve a refreshing effect.
For example, chinese patent CN108310309A discloses a refreshing sachet, the filling medicinal materials of which are composed of rhizoma atractylodis, clove, agastache rugosus, fennel, cassia twig, eupatorium, fructus amomi, polygonum cuspidatum, borneol and sandalwood; the medicinal materials in the sachet are treated by flash extractor or enzymolysis method, so that the loss of effective components in the medicinal materials can be caused, and the borneol is easily oxidized, so that the refreshing effect of the sachet is reduced.
For another example, chinese patent CN103845688A discloses a refreshing sachet, the filling medicinal materials of the sachet are composed of sandalwood, clove, wrinkled gianthyssop herb, turmeric root-tuber, borneol, menthol, camphor, dragon, tree peony bark and Chinese parsley; the sachet is added with camphor, which is not suitable for people with qi deficiency, and the Chinese parsley has large stimulation to the upper respiratory tract, and is easy to cause adverse reaction.
Therefore, there is a need for a traditional Chinese medicine sachet which has no side effect and good refreshing effect.
Disclosure of Invention
Aiming at the problems that the sachet in the prior art has side effects and the refreshing effect is not ideal, the invention provides a refreshing traditional Chinese medicine composition, a sachet and application thereof. The traditional Chinese medicine composition and the traditional Chinese medicine sachet have the advantages of good refreshing effect, no side effect, convenience in use, wide applicable population and air disinfection effect.
In order to achieve the technical effects, the invention adopts the following technical scheme:
firstly, the invention provides a traditional Chinese medicine composition for refreshing, which comprises the following components: the traditional Chinese medicine composition comprises, by weight, 2-4 parts of nardostachys chinensis bunge, 4-6 parts of kaempferia galanga, 2-4 parts of angelica dahurica, 1-3 parts of folium artemisiae argyi, 1-3 parts of mint, 1-3 parts of asarum and 2-4 parts of storax.
Preferably, the Chinese medicinal composition further comprises: 1-3 parts of rhizoma sparganii.
Preferably, the Chinese medicinal composition further comprises: 1-2 parts of rhizoma bolbostemmae.
Preferably, the Chinese medicinal composition further comprises: calculated according to the weight portion, 2-4 portions of common bletilla pseudobulb.
Preferably, the Chinese medicinal composition further comprises: 1-3 parts of celandine by weight.
Most preferably, the Chinese medicinal composition comprises: the traditional Chinese medicine composition comprises, by weight, 3 parts of nardostachys chinensis benth, 5 parts of rhizoma kaempferiae, 3 parts of angelica dahurica, 2 parts of folium artemisiae argyi, 2 parts of mint, 2 parts of asarum, 3 parts of storax, 2 parts of rhizoma sparganii, 1.5 parts of rhizoma bolbostemmae, 3 parts of rhizoma bletillae and 2 parts of celandine.
The invention further provides an application of the traditional Chinese medicine composition in preparation of traditional Chinese medicine sachets.
In addition, the invention also provides a traditional Chinese medicine sachet which comprises a sachet body and the traditional Chinese medicine composition filled in the sachet body.
The preparation method of the traditional Chinese medicine sachet comprises the following steps:
(1) weighing the medicinal materials according to the formula dosage, mixing, crushing, and sieving by a 16-25 mesh sieve to obtain the traditional Chinese medicine composition;
(2) filling the Chinese medicinal composition obtained in the step (1) into a capsule body to obtain the Chinese medicinal sachet.
Wherein the medicinal materials in the step (1) are prepared into traditional Chinese medicine decoction pieces.
In addition, the invention also provides application of the traditional Chinese medicine sachet in air disinfection.
Compared with the prior art, the invention has the following beneficial effects:
1. the traditional Chinese medicine composition provided by the invention comprises, by weight, 2-4 parts of nardostachys chinensis, 4-6 parts of rhizoma kaempferiae, 2-4 parts of angelica dahurica, 1-3 parts of folium artemisiae argyi, 1-3 parts of mint, 1-3 parts of asarum and 2-4 parts of storax, and the applicant reasonably mixes the medicinal materials, so that the traditional Chinese medicine sachet prepared from the medicinal materials has a good refreshing effect;
2. the traditional Chinese medicine sachet has better refreshing effect by creatively adding the rhizoma sparganii, the rhizoma bolbostemmae, the rhizoma bletillae and the celandine on the basis of the nardostachyos root and rhizome, the kaempferia galangal, the angelica dahurica, the folium artemisiae argyi, the mint, the asarum and the storax.
3. The applicant also surprisingly found that the refreshing sachet provided by the invention has the effect of air disinfection.
Detailed Description
The present invention will be further explained with reference to specific embodiments in order to make the technical means, the original characteristics, the achieved objects and the effects of the present invention easy to understand, but the following embodiments are only preferred embodiments of the present invention, and not all embodiments are possible. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative efforts belong to the protection scope of the present invention. The experimental methods in the following examples are conventional methods unless otherwise specified, and materials, reagents and the like used in the following examples are commercially available unless otherwise specified.
Example 1
A traditional Chinese medicine sachet for refreshing, which comprises a sachet body and a traditional Chinese medicine composition filled in the sachet body, wherein the traditional Chinese medicine composition comprises: the traditional Chinese medicine composition comprises, by weight, 2 parts of nardostachys chinensis bunge, 4 parts of kaempferia galanga, 2 parts of angelica dahurica, 1 part of folium artemisiae argyi, 1 part of mint, 1 part of asarum and 2 parts of storax.
The preparation method comprises the following steps:
(1) weighing decoction pieces according to the formula dosage of the composition, mixing, pulverizing, and sieving with 16 mesh sieve to obtain Chinese medicinal composition;
(2) and (2) filling 30g of the traditional Chinese medicine composition obtained in the step (1) into a capsule body to obtain the traditional Chinese medicine sachet.
Example 2
A traditional Chinese medicine sachet for refreshing, which comprises a sachet body and a traditional Chinese medicine composition filled in the sachet body, wherein the traditional Chinese medicine composition comprises: according to the weight parts, 4 parts of nardostachys chinensis benth, 6 parts of kaempferia galanga, 4 parts of angelica dahurica, 3 parts of folium artemisiae argyi, 3 parts of mint, 3 parts of asarum and 4 parts of storax.
The preparation method comprises the following steps:
(1) weighing decoction pieces according to the formula dosage of the composition, mixing, pulverizing, and sieving with 25 mesh sieve to obtain Chinese medicinal composition;
(2) and (2) filling 30g of the traditional Chinese medicine composition obtained in the step (1) into a capsule body to obtain the traditional Chinese medicine sachet.
Example 3
1 part of rhizoma sparganii is added on the basis of the formula of the sachet described in example 1.
The preparation method comprises the following steps:
(1) weighing decoction pieces according to the formula dosage of the composition, mixing, pulverizing, and sieving with 20 mesh sieve to obtain Chinese medicinal composition;
(2) and (2) filling 30g of the traditional Chinese medicine composition obtained in the step (1) into a capsule body to obtain the traditional Chinese medicine sachet.
Example 4
3 parts of rhizoma sparganii are added on the basis of the formula of the sachet in the embodiment 2. The preparation method is the same as example 3.
Example 5
1 part of rhizoma bolbostemmae is added on the basis of the sachet formula in the embodiment 3. The preparation method is the same as example 3.
Example 6
2 parts of rhizoma bolbostemmae are added on the basis of the sachet formula in the embodiment 4. The preparation method is the same as example 3.
Example 7
2 parts of bletilla striata are added on the basis of the sachet formula described in the example 5. The preparation method is the same as example 3.
Example 8
4 parts of bletilla striata is added on the basis of the sachet formula described in the example 6. The preparation method is the same as example 3.
Example 9
1 part of celandine is added on the basis of the formula of the sachet described in the example 7. The preparation method is the same as example 3.
Example 10
3 parts of celandine are added on the basis of the formula of the sachet in the example 8. The preparation method is the same as example 3.
Example 11
A traditional Chinese medicine sachet for refreshing, which comprises a sachet body and a traditional Chinese medicine composition filled in the sachet body, wherein the traditional Chinese medicine composition comprises: the traditional Chinese medicine composition comprises, by weight, 3 parts of nardostachys chinensis benth, 5 parts of rhizoma kaempferiae, 3 parts of angelica dahurica, 2 parts of folium artemisiae argyi, 2 parts of mint, 2 parts of asarum, 3 parts of storax, 2 parts of rhizoma sparganii, 1.5 parts of rhizoma bolbostemmae, 3 parts of rhizoma bletillae and 2 parts of celandine. The preparation method is the same as example 3.
In the preparation method of the sachet described in embodiments 1 to 11, the decoction pieces in step (1) should meet the requirements of Chinese pharmacopoeia (2015 edition), and the specific processing method and characteristics of each traditional Chinese medicine decoction piece are as follows:
and (3) rhizoma nardostachyos: taking raw medicinal materials, removing impurities and silt, cleaning, cutting into long sections, and drying.
Kaempferia galanga: collecting raw materials, removing impurities, cleaning, and drying.
Radix angelicae: collecting raw materials, removing impurities, separating, slightly soaking, moistening, slicing, and drying.
Folium artemisiae argyi: taking raw medicinal materials, removing impurities and stalks, and screening to remove dust.
Mint: taking raw medicinal materials, removing old stems and impurities, slightly spraying clear water, slightly moistening, cutting into short segments, and drying at low temperature in time.
Asarum: taking raw medicinal materials, removing impurities, spraying clear water, slightly moistening, cutting into segments, and drying in the shade.
Storax: taking raw medicinal materials, removing impurities, and grinding.
Three-edge: collecting raw materials, removing impurities, soaking, moistening, slicing, and drying.
Paniculate Bolbostemma rhizome: collecting raw materials, removing impurities, slicing, and drying.
And (3) common bletilla pseudobulb: cleaning raw materials, moistening, slicing, and sun drying.
Herba Chelidonii: taking raw medicinal materials, removing impurities, spraying clear water, slightly moistening, cutting into segments, and drying.
Comparative example
Chinese patent CN 103845688A.
Experimental example 1 experiment of refreshing effect of sachet
Volunteers (brain workers such as college students and office workers) were recruited, and 13 points a day were placed on the desk for 2 hours. After one week of each sachet use, the following evaluation criteria were scored (1 point lowest, 10 points highest) with score values of 1 point, 2 points, … …, and so on to 10 points. And calculating the average score of each index to obtain the comprehensive score of each sachet.
Figure BDA0002036147320000061
Figure BDA0002036147320000071
Experimental example 2 experiment of air sterilizing action of sachet
1. The experimental environment is as follows: select 50m3A large room and a small room.
2. Experimental materials: impact air microorganism sampler (from Qingdao environmental protection equipment Co., Ltd., model FA-1) and culture dish
Figure BDA0002036147320000072
A culture medium (nutrient agar medium), a constant temperature incubator, an autoclave, and the like. Preparing a nutrient agar culture medium by a conventional method, wherein the components are as follows: 20g of peptone, 3g of beef extract, 5g of sodium chloride, 15g of agar and 1000mL of distilled water, wherein the pH value is 7.4, and the components are injected into a culture dish after autoclaving.
3. The experimental method comprises the following steps:
sampling point selection: the distance from the wall is 1.0 meter and the ventilation opening is avoided, and 4 corners and the middle of the room are taken as sampling points.
The sampling method comprises the following steps: before disinfection, sampling natural bacteria in the air by using an impact type sampler to serve as a sample before disinfection; placing the traditional Chinese medicine sachets at the sampling points respectively, standing for 6 hours at a height of 1 m from the ground, taking the samples as sterilized samples, and repeatedly measuring for 3 times. The sampling flow of the sampler is 28.3L/min, and the sampling time is 2 min.
Culturing: and (3) placing the sampled plate in a constant-temperature incubator at 36 +/-1 ℃ for culturing for 48h, obtaining the number of bacterial colonies in each cubic meter of air according to the flow and sampling time of the sampler, and calculating the sterilization rate.
The formula: total number of air bacterial colonies (cfu/m)3) 1000 × N/(t × v), N-plate colony count (cfu), t-sample time (min), v-sample flow (L/min); the sterilization rate (number of colonies before sterilization-number of colonies after sterilization)/number of colonies before sterilization × 100%.
4. The experimental results are as follows:
number of colonies cfu/m3 before Disinfection Number of sterilized colonies cfu/m3 Bacteria removal rate
Example 1 1736.33±16.54 1459.67±10.21 15.93%
Example 2 1819.00±25.81 1465.67±7.54 19.42%
Example 3 1713.67±9.53 1455.33±14.20 15.07%
Example 4 1709.33±22.43 1423.33±23.68 16.73%
Example 5 1751.00±28.08 1475.00±27.58 15.76%
Example 6 1640.00±24.26 1435.67±8.06 12.46%
Example 7 1720.67±22.88 1481.33±5.44 13.91%
Example 8 1673.67±19.19 1428.33±17.15 14.66%
Example 9 1687.33±21.51 1320.67±15.17 21.73%
Example 10 1668.00±19.25 1301.00±9.20 22.00%
Example 11 1742.33±20.93 1343.33±12.92 22.90%
Comparative example 1756.00±25.73 1723.67±18.37 1.84%
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (2)

1. An application of a traditional Chinese medicine sachet in air disinfection is characterized in that: the traditional Chinese medicine sachet consists of a sachet body and a traditional Chinese medicine composition filled in the sachet body; the traditional Chinese medicine composition comprises, by weight, 2-4 parts of nardostachys chinensis benth, 4-6 parts of kaempferia galanga, 2-4 parts of angelica dahurica, 1-3 parts of folium artemisiae argyi, 1-3 parts of mint, 1-3 parts of asarum, 2-4 parts of storax, 1-3 parts of rhizoma sparganii, 1-2 parts of rhizoma bolbostemmae, 2-4 parts of rhizoma bletillae and 1-3 parts of celandine;
the preparation method of the traditional Chinese medicine sachet comprises the following steps:
(1) weighing the medicinal materials according to the formula dosage, mixing, crushing, and sieving by a 16-25 mesh sieve to obtain the traditional Chinese medicine composition;
(2) filling the Chinese medicinal composition obtained in the step (1) into a capsule body to obtain a Chinese medicinal sachet;
the medicinal materials in the step (1) are prepared into traditional Chinese medicine decoction pieces.
2. Use according to claim 1, characterized in that: the traditional Chinese medicine composition comprises, by weight, 3 parts of nardostachys chinensis benth, 5 parts of rhizoma kaempferiae, 3 parts of radix angelicae, 2 parts of folium artemisiae argyi, 2 parts of mint, 2 parts of asarum, 3 parts of storax, 2 parts of rhizoma sparganii, 1.5 parts of rhizoma bolbostemmae, 3 parts of rhizoma bletillae and 2 parts of celandine.
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