CN109890952A - 灌注生物反应器袋装配 - Google Patents

灌注生物反应器袋装配 Download PDF

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Publication number
CN109890952A
CN109890952A CN201780067980.9A CN201780067980A CN109890952A CN 109890952 A CN109890952 A CN 109890952A CN 201780067980 A CN201780067980 A CN 201780067980A CN 109890952 A CN109890952 A CN 109890952A
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CN
China
Prior art keywords
bioreactor
cell
bag
packed
erratically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201780067980.9A
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English (en)
Chinese (zh)
Inventor
P·博切斯
C·D·瓦尔堡
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Juno Therapeutics Inc
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Juno Therapeutics Inc
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Publication of CN109890952A publication Critical patent/CN109890952A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/06—Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Water Supply & Treatment (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201780067980.9A 2016-09-12 2017-09-12 灌注生物反应器袋装配 Pending CN109890952A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662393583P 2016-09-12 2016-09-12
US62/393,583 2016-09-12
PCT/US2017/051228 WO2018049420A1 (en) 2016-09-12 2017-09-12 Perfusion bioreactor bag assemblies

Publications (1)

Publication Number Publication Date
CN109890952A true CN109890952A (zh) 2019-06-14

Family

ID=59955681

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780067980.9A Pending CN109890952A (zh) 2016-09-12 2017-09-12 灌注生物反应器袋装配

Country Status (12)

Country Link
US (1) US20190211292A1 (https=)
EP (1) EP3510136A1 (https=)
JP (1) JP2019526269A (https=)
KR (1) KR20190045321A (https=)
CN (1) CN109890952A (https=)
AU (1) AU2017322752A1 (https=)
BR (1) BR112019004662A2 (https=)
CA (1) CA3035829A1 (https=)
MA (1) MA46194A (https=)
MX (1) MX2019002765A (https=)
RU (2) RU2755725C2 (https=)
WO (1) WO2018049420A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3990610A4 (en) * 2019-06-30 2023-11-01 Saint-Gobain Performance Plastics Corporation CELL CULTURE SYSTEM

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US11149244B2 (en) 2018-04-04 2021-10-19 Southwest Research Institute Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy
US11118149B2 (en) * 2018-04-25 2021-09-14 Global Life Sciences Solutions Usa Llc Bioreactor bags
SG11202102986XA (en) 2018-09-24 2021-04-29 Southwest Res Inst Three-dimensional bioreactors
KR102912306B1 (ko) * 2018-11-28 2026-01-15 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 필터를 구비하는 생물반응기
EP4133057A4 (en) * 2020-04-10 2025-04-16 Southwest Research Institute Three-dimensional bioreactor for viral vector production
US12539515B2 (en) 2021-10-28 2026-02-03 Southwest Research Institute Devices for cell separation
WO2024122708A1 (ko) * 2022-12-07 2024-06-13 주식회사 팡세 생물반응기 시스템 및 이를 이용한 세포 배양방법
WO2024122714A1 (ko) * 2022-12-07 2024-06-13 주식회사 팡세 투석장치 및 이를 포함하는 생물반응기 시스템

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CN102482633A (zh) * 2009-07-06 2012-05-30 弗·哈夫曼-拉罗切有限公司 真核细胞的培养方法
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3990610A4 (en) * 2019-06-30 2023-11-01 Saint-Gobain Performance Plastics Corporation CELL CULTURE SYSTEM

Also Published As

Publication number Publication date
BR112019004662A2 (pt) 2019-05-28
RU2019110824A3 (https=) 2021-01-22
RU2021123536A (ru) 2022-01-14
WO2018049420A1 (en) 2018-03-15
NZ752132A (en) 2022-03-25
JP2019526269A (ja) 2019-09-19
US20190211292A1 (en) 2019-07-11
RU2755725C2 (ru) 2021-09-20
CA3035829A1 (en) 2018-03-15
EP3510136A1 (en) 2019-07-17
MA46194A (fr) 2019-07-17
RU2019110824A (ru) 2020-10-12
AU2017322752A1 (en) 2019-03-21
MX2019002765A (es) 2019-05-09
KR20190045321A (ko) 2019-05-02

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