CN109890952A - 灌注生物反应器袋装配 - Google Patents

灌注生物反应器袋装配 Download PDF

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Publication number
CN109890952A
CN109890952A CN201780067980.9A CN201780067980A CN109890952A CN 109890952 A CN109890952 A CN 109890952A CN 201780067980 A CN201780067980 A CN 201780067980A CN 109890952 A CN109890952 A CN 109890952A
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China
Prior art keywords
bioreactor
cell
bag
packed
erratically
Prior art date
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Pending
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CN201780067980.9A
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English (en)
Chinese (zh)
Inventor
P·博切斯
C·D·瓦尔堡
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Juno Therapeutics Inc
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Juno Therapeutics Inc
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Publication of CN109890952A publication Critical patent/CN109890952A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/06—Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Water Supply & Treatment (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201780067980.9A 2016-09-12 2017-09-12 灌注生物反应器袋装配 Pending CN109890952A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662393583P 2016-09-12 2016-09-12
US62/393,583 2016-09-12
PCT/US2017/051228 WO2018049420A1 (en) 2016-09-12 2017-09-12 Perfusion bioreactor bag assemblies

Publications (1)

Publication Number Publication Date
CN109890952A true CN109890952A (zh) 2019-06-14

Family

ID=59955681

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780067980.9A Pending CN109890952A (zh) 2016-09-12 2017-09-12 灌注生物反应器袋装配

Country Status (12)

Country Link
US (1) US20190211292A1 (enExample)
EP (1) EP3510136A1 (enExample)
JP (1) JP2019526269A (enExample)
KR (1) KR20190045321A (enExample)
CN (1) CN109890952A (enExample)
AU (1) AU2017322752A1 (enExample)
BR (1) BR112019004662A2 (enExample)
CA (1) CA3035829A1 (enExample)
MA (1) MA46194A (enExample)
MX (1) MX2019002765A (enExample)
RU (2) RU2755725C2 (enExample)
WO (1) WO2018049420A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3990610A4 (en) * 2019-06-30 2023-11-01 Saint-Gobain Performance Plastics Corporation CELL CULTURE SYSTEM

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US11149244B2 (en) 2018-04-04 2021-10-19 Southwest Research Institute Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy
US11118149B2 (en) * 2018-04-25 2021-09-14 Global Life Sciences Solutions Usa Llc Bioreactor bags
SG11202102986XA (en) 2018-09-24 2021-04-29 Southwest Res Inst Three-dimensional bioreactors
JP7490294B2 (ja) * 2018-11-28 2024-05-27 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー フィルタを有するバイオリアクタ
KR20220166825A (ko) * 2020-04-10 2022-12-19 사우스웨스트 리서치 인스티튜트 바이러스 벡터 생산을 위한 3차원 생물 반응기
WO2024122708A1 (ko) * 2022-12-07 2024-06-13 주식회사 팡세 생물반응기 시스템 및 이를 이용한 세포 배양방법
WO2024122714A1 (ko) * 2022-12-07 2024-06-13 주식회사 팡세 투석장치 및 이를 포함하는 생물반응기 시스템

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US20030036192A1 (en) * 2001-02-15 2003-02-20 Vijay Singh Disposable perfusion bioreactor for cell culture
CN102482633A (zh) * 2009-07-06 2012-05-30 弗·哈夫曼-拉罗切有限公司 真核细胞的培养方法
WO2012128703A1 (en) * 2011-03-18 2012-09-27 Ge Healthcare Bio-Sciences Ab Flexible bag for cultivation of cells
CN202430231U (zh) * 2012-01-19 2012-09-12 台湾尖端先进生技医药股份有限公司 可供给培养添加物的悬浮性细胞封闭培养系统
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3990610A4 (en) * 2019-06-30 2023-11-01 Saint-Gobain Performance Plastics Corporation CELL CULTURE SYSTEM

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KR20190045321A (ko) 2019-05-02
MA46194A (fr) 2019-07-17
NZ752132A (en) 2022-03-25
CA3035829A1 (en) 2018-03-15
BR112019004662A2 (pt) 2019-05-28
RU2021123536A (ru) 2022-01-14
RU2019110824A (ru) 2020-10-12
WO2018049420A1 (en) 2018-03-15
EP3510136A1 (en) 2019-07-17
AU2017322752A1 (en) 2019-03-21
MX2019002765A (es) 2019-05-09
JP2019526269A (ja) 2019-09-19
RU2019110824A3 (enExample) 2021-01-22
RU2755725C2 (ru) 2021-09-20
US20190211292A1 (en) 2019-07-11

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