CN109833439A - A kind of uterine neck Chinese medicine composition, preparation method and application - Google Patents

A kind of uterine neck Chinese medicine composition, preparation method and application Download PDF

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Publication number
CN109833439A
CN109833439A CN201910312910.6A CN201910312910A CN109833439A CN 109833439 A CN109833439 A CN 109833439A CN 201910312910 A CN201910312910 A CN 201910312910A CN 109833439 A CN109833439 A CN 109833439A
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China
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parts
chinese medicine
medicine composition
treatment
uterine neck
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李谦
陈武韬
李醒凤
李秋实
魏超颖
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SICHUAN LGLITTER TECHNOLOGY GROUP Co.,Ltd.
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Sichuan Liangjianda Health Technology Co Ltd
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Abstract

The invention discloses a kind of uterine neck Chinese medicine composition, preparation method and applications, belong to field of medicaments, are a kind of Chinese medicine compositions different from being currently used for prevention and treatment cervicitis medicine.The uterine neck Chinese medicine composition includes viola mandshurica, Sculellaria barbata, semen momordicae, dandelion, subprostrate sophora, Cortex Phellodendri, creeping oxalis, centella.The application is based on traditional Chinese medicinal components, by the compounding between component, to realize the treatment to cervicitis.The application be based on theory of traditional Chinese medical science, based on clearing heat and detoxicating possessed by component, clearing damp and promoting diuresis, activating microcirculation and removing stasis medicinal, swelling and pain relieving, removing toxic substances and promoting tissue regeneration, apocenosis dispel corruption, promoting granulation and wound healing, restrain skin care the effect of, play the purpose for the treatment of both manifestation and root cause of disease.Chronic cervicitis (including cervical erosion, cervical polyp, cervical cyst, endocervicitis) etc. is treated using the application, there is good effect, feature uneasy to recur has remarkable progress.

Description

A kind of uterine neck Chinese medicine composition, preparation method and application
Technical field
The present invention relates to field of medicaments, specially a kind of uterine neck Chinese medicine composition, preparation method and application.The application Chinese medicine composition can be used in the treatment of cervical erosion, cervical polyp, cervical cyst, endocervicitis, there is preferable application Effect.
Background technique
Cervicitis be uterine neck be damaged with pathogen invasion and cause, including portio vaginalis cervicis inflammation and canal of uterine cervix mucous membrane Inflammation.Uterine neck is the important defence line for preventing Lower genital tract pathogen from entering upper genital tract, but cervical canal simple columnar epithelium itself Anti-infection ability is poor, if being damaged by mechanical irritations such as sexual intercourse, childbirth, miscarriage, operations, is just easier to infect.Face Cervicitis is divided into acute and chronic two kinds on bed, is more with chronic inflammation.Chronic cervicitis have cervical erosion, cervical hypertrophy, A variety of performances such as cervical polyp, Nabothcyst and cervical ectropion.
Currently, treatment chronic cervicitis there are many methods, physical therapy and medicinal treatment can be divided into, physical therapy is with laser Carbon dioxide laser defocus irradiation is used for irradiation, 70 watts of power, is irradiated 10-15 minutes every time, 10 times as a treatment course.It is this The treatment method time is long, costly.
For this purpose, China granted patent ZL201710741192.5 discloses a kind of active ingredient for anti-treating cervicitis Object, it discloses a kind of new reactive compounds, have good inhibiting effect for Btk, can be consequently used for inflammatory disease In the prevention and treatment of case such as cervicitis.
Research based on inventor, inventor provide a kind of Chinese medicine group different from existing anti-treating cervicitis reactive compound Object is closed, to realize the treatment to cervical erosion, cervical polyp, cervical cyst, endocervicitis etc..
Summary of the invention
Goal of the invention of the invention is: providing a kind of uterine neck Chinese medicine composition, preparation method and application, is one Kind is different from being currently used for the Chinese medicine composition of prevention and treatment cervicitis medicine.The application divides it based on traditional Chinese medicinal components, through group Between compounding, to realize treatment to cervicitis.The application is based on theory of traditional Chinese medical science, based on clearing heat and detoxicating, sharp possessed by component Water excreting dampness, activating microcirculation and removing stasis medicinal, swelling and pain relieving, removing toxic substances and promoting tissue regeneration, apocenosis dispel corruption, promoting granulation and wound healing, convergence skin care the effect of, it is simultaneous to play sample The purpose controlled.Chronic cervicitis (including cervical erosion, cervical polyp, cervical cyst, endocervicitis) etc. is treated using the application, With good effect, feature uneasy to recur has remarkable progress.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of uterine neck Chinese medicine composition, the component including following weight fraction ratio: 20~40 parts of viola mandshurica, Sculellaria barbata 20~ 40 parts, 1~1.5 part of semen momordicae, 20~50 parts of dandelion, 5 ~ 10 parts of subprostrate sophora, 5~15 parts of Cortex Phellodendri, 20~40 parts of creeping oxalis, product Avenge careless 20~50 parts, 5~15 parts of Asian puccoon, 10~20 parts of glutinous rehmannia, 5~15 parts of cape jasmine, 10~20 parts of carbonized hair, folium callicarpae pedunculatae 10~20 Part, 2~4 parts of dragon's blood, 10~20 parts of Radix Notoginseng, 10~20 parts of Poria cocos, 50 ~ 70 parts of rough melic herb, 20~40 parts of Sheepear Inula Herb, the stem pith of the rice-paper plant 5~ 10 parts, 10~20 parts of humulus grass, 10~20 parts of myrrh, 5 ~ 15 parts of excrementum pteropi, 20~40 parts of motherwort, 5~15 parts of Artemisia anomala, ground beetle 5~15 parts of worm, 20~40 parts of Radix Astragali, 20~40 parts of Radix Codonopsis, 5~15 parts of Cortex hibisus syriacus, 2~4 parts of borax, 5~10 parts of calamine, ice 3~7 parts of piece.
The preparation method of aforementioned uterine neck Chinese medicine composition includes the following steps: to weigh each component according to the ratio, mixes, grind It wears into point.
After component after grinding is mixed, bottling disinfection is spare.
Application of the aforementioned uterine neck Chinese medicine composition in preparation treatment cervicitis medicine.
Aforementioned uterine neck is used to prepare in the drug for the treatment of chronic cervicitis with Chinese medicine composition.
Aforementioned uterine neck is used to prepare treatment cervical erosion, cervical polyp, cervical cyst, endocervicitis with Chinese medicine composition Drug in.
For foregoing problems, the application provides a kind of uterine neck Chinese medicine composition, preparation method and application.It is controlled with doctor trained in Western medicine It is different using sterilization, suppression therapy to treat cervicitis, the application emphasizes treating both manifestation and root cause of disease, raises and combines, effectively reduces the anti-of cervicitis Recurrence is made.
Chinese medicine thinks that cervical disease is mostly by marrying too early, sexual strain fecund or emotional stress, the obstruction of the circulation of vital energy impariment of the liver or damp and hot invasion, with To stagnation of QI-blood, channels and collaterals obstruction or hot and humid ecchymosis are mutually tied in uterus, caused by blood slough loses.It is recorded in " Synopsis Golden Chamber ", " married woman Disease break off because of void product cold junction gas for Zhu Jingshui, until having over the years, pathogenic cold coagulating with blood, uterus injured by cold, meridian and collateral being blocked." " all pathogenies are waited By " in record, " leukorrhagia patient damages dynamic chong channel conception vessel by internal lesion caused by overexertion vim and vigour, cause enable its blood and dirty liquid phase and band and under.Both " The origin cause of formation and punching for all discussing this disease are appointed by the relationship for undermining exopathogen six external factors which cause diseases visitor and entering.For this purpose, the application is based on etiology and pathogenesis, select Viola mandshurica, semen momordicae, dandelion, Cortex Phellodendri, creeping oxalis, centella, Asian puccoon, glutinous rehmannia, cape jasmine, carbonized hair, folium callicarpae pedunculatae, the rose of Sharon Skin, borax progress are clearing heat and detoxicating, and dragon's blood, Radix Notoginseng carry out convergence removing blood stasis and hemostasis, Poria cocos, rough melic herb, Sheepear Inula Herb, the stem pith of the rice-paper plant, humulus grass, furnace Sweet stone progress inducing diuresis for removing edema, myrrh, excrementum pteropi, motherwort, Artemisia anomala, ground bettle progress activating microcirculation and removing stasis medicinal, borneol swelling and pain relieving, and Cooperate Sculellaria barbata, Radix Astragali, Radix Codonopsis, subprostrate sophora mutually to swash effect, achievees the purpose that heighten the effect of a treatment, treating both manifestation and root cause of disease.
Further, the preparation method of the uterine neck Chinese medicine composition is claimed in the application comprising following steps: by tradition Preparation method, pulverization, bottling disinfection are spare.Match with existing related drugs, the application preparation process is simple, easily It is operated in promoting, production cost is low, the period is short.Meanwhile the characteristic based on preparation process so that preparation drug be easy to carry about with one, Preservation has extremely strong convenience.
Inventor has carried out clinical application to drug of the invention, using the result shows that, the present invention is to cervical erosion, uterine neck The Cervicitis such as polyp, cervical cyst, endocervicitis have fabulous therapeutic effect, and cure no relapse in latter year.
Specific embodiment
All features disclosed in this specification or disclosed all methods or in the process the step of, in addition to mutually exclusive Feature and/or step other than, can combine in any way.
Any feature disclosed in this specification unless specifically stated can be equivalent or with similar purpose by other Alternative features are replaced.That is, unless specifically stated, each feature is an example in a series of equivalent or similar characteristics ?.
(1) preparation step of following embodiments 1 ~ 5 is as follows: each component is weighed according to the ratio, is uniformly mixed, is ground into fine powder, Bottling disinfection is spare.
Embodiment 1
The Chinese medicine composition of the present embodiment includes the component of following weight fraction ratio: 22 parts of viola mandshurica, 35 parts of Sculellaria barbata, Momordica cochinchiensis Sub 1.5 parts, 45 parts of dandelion, 8 parts of subprostrate sophora, 10 parts of Cortex Phellodendri, 35 parts of creeping oxalis, 40 parts of centella, 12 parts of Asian puccoon, glutinous rehmannia 18 Part, 12 parts of cape jasmine, 10 parts of carbonized hair, 15 parts of folium callicarpae pedunculatae, 2 parts of dragon's blood, 18 parts of Radix Notoginseng, 16 parts of Poria cocos, 65 parts of rough melic herb, Sheepear Inula Herb 35 parts, 8 parts of the stem pith of the rice-paper plant, 17 parts of humulus grass, 15 parts of myrrh, 15 parts of excrementum pteropi, 35 parts of motherwort, 14 parts of Artemisia anomala, 12 parts of ground bettle, Huang 35 parts of stilbene, 26 parts of Radix Codonopsis, 8 parts of Cortex hibisus syriacus, 2 parts of borax, 6 parts of calamine, 6 parts of borneol.
Embodiment 2
The Chinese medicine composition of the present embodiment includes the component of following weight fraction ratio: 25 parts of viola mandshurica, 30 parts of Sculellaria barbata, Momordica cochinchiensis Son 1.3 parts, 40 parts of dandelion, 7 parts of subprostrate sophora, 6 parts of Cortex Phellodendri, 30 parts of creeping oxalis, 35 parts of centella, 10 parts of Asian puccoon, 15 parts of glutinous rehmannia, 10 parts of cape jasmine, 18 parts of carbonized hair, 16 parts of folium callicarpae pedunculatae, 3 parts of dragon's blood, 16 parts of Radix Notoginseng, 15 parts of Poria cocos, 60 parts of rough melic herb, Sheepear Inula Herb 25 Part, 7 parts of the stem pith of the rice-paper plant, 12 parts of humulus grass, 15 parts of myrrh, 8 parts of excrementum pteropi, 35 parts of motherwort, 7 parts of Artemisia anomala, 10 parts of ground bettle, Radix Astragali 35 Part, 30 parts of Radix Codonopsis, 6 parts of Cortex hibisus syriacus, 2 parts of borax, 8 parts of calamine, 5 parts of borneol.
Embodiment 3
The Chinese medicine composition of the present embodiment includes the component of following weight fraction ratio: 38 parts of viola mandshurica, 30 parts of Sculellaria barbata, Momordica cochinchiensis Son 1.1 parts, 25 parts of dandelion, 8 parts of subprostrate sophora, 10 parts of Cortex Phellodendri, 33 parts of creeping oxalis, 25 parts of centella, 6 parts of Asian puccoon, 10 parts of glutinous rehmannia, 8 parts of cape jasmine, 12 parts of carbonized hair, 12 parts of folium callicarpae pedunculatae, 3 parts of dragon's blood, 12 parts of Radix Notoginseng, 10 parts of Poria cocos, 52 parts of rough melic herb, Sheepear Inula Herb 30 Part, 9 parts of the stem pith of the rice-paper plant, 15 parts of humulus grass, 11 parts of myrrh, 10 parts of excrementum pteropi, 30 parts of motherwort, 9 parts of Artemisia anomala, 15 parts of ground bettle, Radix Astragali 30 parts, 35 parts of Radix Codonopsis, 12 parts of Cortex hibisus syriacus, 3 parts of borax, 5 parts of calamine, 4 parts of borneol.
Embodiment 4
The Chinese medicine composition of the present embodiment includes the component of following weight fraction ratio: 30 parts of viola mandshurica, 25 parts of Sculellaria barbata, Momordica cochinchiensis Son 1 part, 30 parts of dandelion, 10 parts of subprostrate sophora, 12 parts of Cortex Phellodendri, 28 parts of creeping oxalis, 30 parts of centella, 15 parts of Asian puccoon, 16 parts of glutinous rehmannia, 11 parts of cape jasmine, 15 parts of carbonized hair, 18 parts of folium callicarpae pedunculatae, 2 parts of dragon's blood, 15 parts of Radix Notoginseng, 18 parts of Poria cocos, 63 parts of rough melic herb, Sheepear Inula Herb 30 Part, 6 parts of the stem pith of the rice-paper plant, 20 parts of humulus grass, 18 parts of myrrh, 12 parts of excrementum pteropi, 25 parts of motherwort, 11 parts of Artemisia anomala, 8 parts of ground bettle, Radix Astragali 40 parts, 28 parts of Radix Codonopsis, 11 parts of Cortex hibisus syriacus, 4 parts of borax, 9 parts of calamine, 7 parts of borneol.
Embodiment 5
The Chinese medicine composition of the present embodiment includes the component of following weight fraction ratio: 33 parts of viola mandshurica, 20 parts of Sculellaria barbata, Momordica cochinchiensis Son 1.2 parts, 35 parts of dandelion, 6 parts of subprostrate sophora, 15 parts of Cortex Phellodendri, 38 parts of creeping oxalis, 46 parts of centella, 8 parts of Asian puccoon, 20 parts of glutinous rehmannia, 13 parts of cape jasmine, 16 parts of carbonized hair, 10 parts of folium callicarpae pedunculatae, 4 parts of dragon's blood, 20 parts of Radix Notoginseng, 12 parts of Poria cocos, 65 parts of rough melic herb, Sheepear Inula Herb 20 Part, 5 parts of the stem pith of the rice-paper plant, 10 parts of humulus grass, 16 parts of myrrh, 12 parts of excrementum pteropi, 32 parts of motherwort, 6 parts of Artemisia anomala, 15 parts of ground bettle, Radix Astragali 25 parts, 22 parts of Radix Codonopsis, 6 parts of Cortex hibisus syriacus, 2 parts of borax, 6 parts of calamine, 5 parts of borneol.
(2) clinical test
1, using cervicitises such as the traditional Chinese medicine composition for treating cervical erosion of the application, cervical polyp, cervical cyst, endocervicitis Disease, clinical manifestation are leucorrhea increasing, are in thick or mycopus, sometimes with the trace of blood.Since patient exists individually Illness or the concurrent situation of more diseases, for convenient for distinguishing the effects of clinic diagnosis to different symptoms, according to the different symptoms of Cervicitis into Row statistic of classification.
2, therapeutic scheme
For the Cervicitis for having above-mentioned symptom, treated by the way of oral administration medicament, it is early, middle and late each primary.It is within one week 3-6 course for the treatment of statistics curative effect can be used continuously in one course for the treatment of.
3, efficacy assessment standard
Clinical cure: symptom completely disappears, and life is as usual, and without recurrence in half a year.
Effective: symptom has clear improvement or improves, and need to continue medication treatment.
Invalid: symptom is without improvement, or even has the trend of exacerbation, needs that other technological approaches is separately selected to be treated.
4, the test period: 18 months
5, result counts
165 patients are treated using the above scheme, correlation circumstance is as follows:
1) cervical erosion 96,1 course for the treatment of cure 23 patients, and 2 courses for the treatment of cure 55 patients, and 3 courses for the treatment of cure 12 trouble Person, effective 6;
2) cervical polyp 62,1 course for the treatment of cure 3 patients, and 2 courses for the treatment of cure 18 patients, and 3 courses for the treatment of cure 34 trouble Person, effective 7;
3) cervical cyst 55,1 course for the treatment of cure 18 patients, and 2 courses for the treatment of cure 20 patients, and 3 courses for the treatment of cure 16 trouble Person, effective 1;
4) endocervicitis 123,1 course for the treatment of cure 7 patients, and 2 courses for the treatment of cure 65 patients, and 3 courses for the treatment of cure 50 trouble Person, effective 1.
Above-mentioned treatment results show to achieve preferable effect using present invention treatment Cervicitis, and find no Toxic side effect shows that curative effect is stablized, efficient high.Meanwhile the cure rate of patient is high, the later period probability of recurrence is small, illustrates this Shen Drug please plays preferable treating both manifestation and root cause of disease effect.
The invention is not limited to specific embodiments above-mentioned.The present invention, which expands to, any in the present specification to be disclosed New feature or any new combination, and disclose any new method or process the step of or any new combination.

Claims (6)

1. a kind of uterine neck Chinese medicine composition, which is characterized in that the component including following weight fraction ratio: viola mandshurica 20~40 Part, 20~40 parts of Sculellaria barbata, 1~1.5 part of semen momordicae, 20~50 parts of dandelion, 5 ~ 10 parts of subprostrate sophora, 5~15 parts of Cortex Phellodendri, jealous woman slurry Careless 20~40 parts, 20~50 parts of centella, 5~15 parts of Asian puccoon, 10~20 parts of glutinous rehmannia, 5~15 parts of cape jasmine, carbonized hair 10~20 Part, 10~20 parts of folium callicarpae pedunculatae, 2~4 parts of dragon's blood, 10~20 parts of Radix Notoginseng, 10~20 parts of Poria cocos, 50 ~ 70 parts of rough melic herb, Sheepear Inula Herb 20~40 parts, 5~10 parts of the stem pith of the rice-paper plant, 10~20 parts of humulus grass, 10~20 parts of myrrh, 5 ~ 15 parts of excrementum pteropi, 20~40 parts of motherwort, Liu Post 5~15 parts of slave, 5~15 parts of ground bettle, 20~40 parts of Radix Astragali, 20~40 parts of Radix Codonopsis, 5~15 parts of Cortex hibisus syriacus, 2~4 parts of borax, 5~10 parts of calamine, 3~7 parts of borneol.
2. the preparation method of uterine neck Chinese medicine composition according to claim 1, which comprises the steps of: press Proportion weighs each component, mixes, and grinds ingredient.
3. preparation method according to claim 1 or 2, which is characterized in that after the component after grinding is mixed, bottling disinfection It is spare.
4. application of the aforementioned uterine neck Chinese medicine composition in preparation treatment cervicitis medicine according to claim 1.
5. application according to claim 4, which is characterized in that aforementioned uterine neck is used to prepare treatment slowly with Chinese medicine composition In the drug of property cervicitis.
6. according to the described in any item applications of claim 4 ~ 6, which is characterized in that aforementioned uterine neck to be used to make with Chinese medicine composition Standby treatment cervical erosion, cervical polyp, cervical cyst, endocervicitis drug in.
CN201910312910.6A 2019-04-18 2019-04-18 A kind of uterine neck Chinese medicine composition, preparation method and application Pending CN109833439A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110302306A (en) * 2019-08-12 2019-10-08 南京依美生物科技有限公司 A kind of Chinese medicine composition and preparation method thereof for treating Nabothian cyst

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘玉成: "《赐嗣:不孕症诊疗理论与实践》", 31 October 2006, 军事医学科学出版社 *
王佃亮: "《中医医师处方》", 30 September 2018, 中国协和医科大学出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110302306A (en) * 2019-08-12 2019-10-08 南京依美生物科技有限公司 A kind of Chinese medicine composition and preparation method thereof for treating Nabothian cyst

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