CN105943973A - Traditional Chinese medicine composition for treating lumbar pain after epidural anesthesia - Google Patents

Traditional Chinese medicine composition for treating lumbar pain after epidural anesthesia Download PDF

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CN105943973A
CN105943973A CN201610480449.1A CN201610480449A CN105943973A CN 105943973 A CN105943973 A CN 105943973A CN 201610480449 A CN201610480449 A CN 201610480449A CN 105943973 A CN105943973 A CN 105943973A
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chinese medicine
caulis
medicine composition
radix
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张佣来
李�浩
燕博
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Abstract

The invention belongs to the field of medical technology, and particularly relates to a traditional Chinese medicine composition for treating lumbar pain after epidural anesthesia. The traditional Chinese medicine composition comprises the following traditional Chinese medicine in parts by weight: 11-19 parts of rhaphidophora decursiva, 3-7 parts of ramulus cinnamomi, 6-14 parts of ramulus mori, 4-8 parts of leaves and branchlets of twotooth achyranthes, 6-14 parts of millettia dielsiana, 6-14 parts of phryma leptostachya, 6-14 parts of lycopodium japonicum, 6-14 parts of scirpus fluviatilis, 6-14 parts of salvia miltiorrhiza, 6-14 parts of caulis trachelospermi, 4-8 parts of squama manis, 6-14 parts of clematis chinensis osbeck, 11-19 parts of coix seed, 6-10 parts of lignum sappan and 4-8 parts of licorice. The traditional Chinese medicine ingredients are compatible with one another and collectively achieve the effects of activating blood, removing stasis, dredging collaterals, dispelling dampness, removing paralysis and relieving pain. The traditional Chinese medicine composition is used to treat lumbar pain after epidural anesthesia, and has the advantages of high total effective rate and less adverse reactions.

Description

A kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation
Technical field
The invention belongs to pharmaceutical technology field, be specifically related to a kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation.
Background technology
After epidural anesthesia, lumbago is the postoperative pain that a kind of comparison is special, and its incidence rate generally may be up to 44%, about 3%-11.5% Epidural anesthesia after lumbago will can not alleviate for a long time, cause great body and mind wound to patient and badly influence the art of patient Rear quality of life.
Summary of the invention
The technical problem to be solved is to avoid the weak point existing for above-mentioned prior art, it is provided that one treats dura mater The Chinese medicine composition of outer anesthesia Lumbar pain after operation.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation, is made up of the Chinese medicine of following weight portion:
Radix Seu Caulis Rhaphidophorae Decursivae 11-19 part, Ramulus Cinnamomi 3-7 part, Ramulus Mori 6-14 part, Caulis et Folium Achyranthis bidentatae 4-8 part, Caulis Spatholobi 6-14 part, deep Grass 6-14 part, Herba Lycopodii 6-14 part, Rhizoma Sparganii 6-14 part, Radix Salviae Miltiorrhizae 6-14 part, Caulis Trachelospermi 6-14 part, Squama Manis 4-8 part, Radix Clematidis each 6-14 part, Semen Coicis 11-19 part, Lignum Sappan 6-10 part, Radix Glycyrrhizae 4-8 part.
Preferably, the Chinese medicine composition of above-mentioned treatment epidural anesthesia Lumbar pain after operation, it is made up of the Chinese medicine of following weight portion:
Radix Seu Caulis Rhaphidophorae Decursivae 13-17 part, Ramulus Cinnamomi 4-6 part, Ramulus Mori 8-12 part, Caulis et Folium Achyranthis bidentatae 5-7 part, Caulis Spatholobi 8-12 part, deep Grass 8-12 part, Herba Lycopodii 8-12 part, Rhizoma Sparganii 8-12 part, Radix Salviae Miltiorrhizae 8-12 part, Caulis Trachelospermi 8-12 part, Squama Manis 5-7 part, Radix Clematidis each 8-12 part, Semen Coicis 13-17 part, Lignum Sappan 7-9 part, Radix Glycyrrhizae 5-7 part.
It is furthermore preferred that the Chinese medicine composition of above-mentioned treatment epidural anesthesia Lumbar pain after operation, it is made up of the Chinese medicine of following weight portion:
Radix Seu Caulis Rhaphidophorae Decursivae 15 parts, 5 parts of bavin osmanthus, Ramulus Mori 10 parts, Caulis et Folium Achyranthis bidentatae 6 parts, Caulis Spatholobi 10 parts, Herba speranskiae tuberculatae 10 parts, stretch Muscle grass 10 parts, Rhizoma Sparganii 10 parts, Radix Salviae Miltiorrhizae 10 parts, Caulis Trachelospermi 10 parts, Squama Manis 6 parts, each 10 parts of Radix Clematidis, Semen Coicis 15 parts, Lignum Sappan 8 parts, 6 parts of Radix Glycyrrhizae.
The ratio of above weight proportion obtains through science screening, for especial patient, such as serious symptom or mild, fat or thin Little patient, can adjust the proportioning of the amount of composition accordingly, be increased or decreased less than 100%, and drug effect is basically unchanged.
The weight portion of said medicine, if in units of g, it is common that the consumption of 1 dose.
In the Chinese medicine composition of the present invention,
Radix Seu Caulis Rhaphidophorae Decursivae is called Cayratia trifolia (L.) Domin, Acer buergerianum Miq．, Malong head lobe, is flown Scolopendra, Red Triangle region maple, great Ye green grapes, little Radix Seu Caulis Rhaphidophorae Decursivae. Climb rattan for vitaceae Folium Trapae precipice and Zhi Nanya climbs rattan Tetrastigma triphyllum (Gagnep.) W.T.Wang The root of [T.yunnanense Gagnep.var.triphyllum Gagnep.] or rattan.Acrid in the mouth；Warm in nature.Function wind-damp dispelling； Dissipating blood stasis swells；Reuniting the fractured tendons and bones.Main rheumatic arthritis；Traumatic injury congestive edema；Fracture；Burn；Ulcerative carbuncle is red and swollen.
Bavin osmanthus another name Cortex Cinnamomi Tamalae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Cortex Cinnamomi, for canella bavin osmanthus Cinnamomum tamala (Buch.-Ham.) Nees et Eberm. the bark of [Laurs tamala Buch.-Ham.] or leaf.Acrid in the mouth；Sweet；Warm in nature.Return liver；Spleen channel.Function temperature is stimulated the menstrual flow Arteries and veins；Promoting the circulation of QI to relieve pain.Main arthralgia due to cold-dampnes；Epigastric pain；Dysmenorrhea；Traumatic injury.
Caulis et Folium Achyranthis bidentatae is the stem and leaf of amaranthaceous plant Radix Achyranthis Bidentatae Achyranthes bidentata Bl..Bitter in the mouth；Acid；Property flat.Return liver, Bladder warp.Function dispelling cold and dampness；Bone and muscle strengthening；Diuresis of blood circulation promoting.Main cold-damp flaccidity syndrome and arthralgia syndrome；Lumbocrural pain；Stranguria with urinary obstruction；Chronic malaria.
In the prescription of Chinese medicine composition of the present invention, other medicines all record in Chinese medicine voluminous dictionary.
The mechanism that after epidural anesthesia, lumbago occurs is the brightest, and main cause is probably the muscular fasciae ligament injury caused by puncture, and draws Play aseptic inflammation, aseptic periostitis and osteochondritis.Inventor thinks that lumbar and back pain patient mostly is wound after epidural anesthesia QI and blood is impaired, and treatment is when with blood circulation promoting and dispersing pathogen accumulation, channels-freeing dampness-dispelling, eliminating impediment pain relieving.
In the Chinese medicine composition of the present invention, it is logical that bavin osmanthus is longer than temperature, can lead to promoting the flow of QI-blood by warming the meridian；The effect of promoting the circulation of QI to relieve pain；Ramulus Mori is longer than Li Guan Joint, promoting fluid production, row water dispels the wind；Caulis et Folium Achyranthis bidentatae dispelling cold and dampness；Bone and muscle strengthening；Diuresis of blood circulation promoting；Radix Seu Caulis Rhaphidophorae Decursivae merit can wind-damp dispelling；Dissipating blood stasis swells, Stopping numbness pain；Squama Manis, lightly seasoned property put down, gas raw meat and alter, it walks the property altered, very careful, thus can declare lead to internal organs, implement meridians, Thoroughly reaching pass key, all blood clotting blood gathers for disease, all can open it；Radix Clematidis is the good medicine of dispelling wind and removing obstruction in the collateral, removing damp and stopping pain；Caulis Spatholobi merit can Expelling wind and activating blood circulation, pain relieving of detoxifying；Herba speranskiae tuberculatae, Herba Lycopodii merit can damp-clearing pain-relieving, active relaxing muscles and tendons；Rhizoma Sparganii, Lignum Sappan, Radix Salviae Miltiorrhizae merit can be lived Blood blood stasis dispelling, dredging collateral reducing swelling and alleviating pain；Caulis Trachelospermi is nature and flavor hardship using warming therapy product, invigorates blood circulation with the meridian dredging and is good at, and is special good in relaxing muscles and tendons and activating QI and blood in the collateral Medicine；Semen Coicis merit can heat clearing away eliminating impediment；Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.All medicine compatibilities, play blood circulation promoting and dispersing pathogen accumulation, channels-freeing dampness-dispelling, eliminating impediment pain relieving altogether Effect.For treating epidural anesthesia Lumbar pain after operation.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about the present invention, But and it is not so limited the present invention.
Embodiment 1
A kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation, each crude drug weight proportion is as follows:
Radix Seu Caulis Rhaphidophorae Decursivae 15g, bavin osmanthus 5g, Ramulus Mori 10g, Caulis et Folium Achyranthis bidentatae 6g, Caulis Spatholobi 10g, Herba speranskiae tuberculatae 10g, Herba Lycopodii 10g, Rhizoma Sparganii 10g, Radix Salviae Miltiorrhizae 10g, Caulis Trachelospermi 10g, Squama Manis 6g, each 10g of Radix Clematidis, Semen Coicis 15g, Lignum Sappan 8g, Radix Glycyrrhizae 6g.
Above-mentioned dosage is 1 dose.Every day 1 dose, it is decocted in water for oral dose, sooner or later sub-service.
Embodiment 2
A kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation, each crude drug weight proportion is as follows:
Radix Seu Caulis Rhaphidophorae Decursivae 13g, Ramulus Cinnamomi 6g, Ramulus Mori 8g, Caulis et Folium Achyranthis bidentatae 7g, Caulis Spatholobi 8g, Herba speranskiae tuberculatae 12g, Herba Lycopodii 8g, three Rib 12g, Radix Salviae Miltiorrhizae 8g, Caulis Trachelospermi 12g, Squama Manis 5g, each 12g of Radix Clematidis, Semen Coicis 13g, Lignum Sappan 9g, Radix Glycyrrhizae 5g.
Above-mentioned dosage is 1 dose.Every day 1 dose, it is decocted in water for oral dose, sooner or later sub-service.
Embodiment 3
A kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation, each crude drug weight proportion is as follows:
Radix Seu Caulis Rhaphidophorae Decursivae 17g, Ramulus Cinnamomi 4g, Ramulus Mori 12g, Caulis et Folium Achyranthis bidentatae 5g, Caulis Spatholobi 12g, Herba speranskiae tuberculatae 8g, Herba Lycopodii 12g, Rhizoma Sparganii 8g, Radix Salviae Miltiorrhizae 12g, Caulis Trachelospermi 8g, Squama Manis 7g, each 8g of Radix Clematidis, Semen Coicis 17g, Lignum Sappan 7g, Radix Glycyrrhizae 7g.
Above-mentioned dosage is 1 dose.Every day 1 dose, it is decocted in water for oral dose, sooner or later sub-service.
Embodiment 4
A kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation, each crude drug weight proportion is as follows:
Radix Seu Caulis Rhaphidophorae Decursivae 11g, Ramulus Cinnamomi 7g, Ramulus Mori 6g, Caulis et Folium Achyranthis bidentatae 8g, Caulis Spatholobi 6g, Herba speranskiae tuberculatae 14g, Herba Lycopodii 6g, three Rib 14g, Radix Salviae Miltiorrhizae 6g, Caulis Trachelospermi 14g, Squama Manis 4g, each 14g of Radix Clematidis, Semen Coicis 11g, Lignum Sappan 10g, Radix Glycyrrhizae 4g.
Above-mentioned dosage is 1 dose.Every day 1 dose, it is decocted in water for oral dose, sooner or later sub-service.
Embodiment 5
A kind of Chinese medicine composition treating epidural anesthesia Lumbar pain after operation, each crude drug weight proportion is as follows:
Radix Seu Caulis Rhaphidophorae Decursivae 19g, Ramulus Cinnamomi 3g, Ramulus Mori 14g, Caulis et Folium Achyranthis bidentatae 4g, Caulis Spatholobi 14g, Herba speranskiae tuberculatae 6g, Herba Lycopodii 14g, Rhizoma Sparganii 6g, Radix Salviae Miltiorrhizae 14g, Caulis Trachelospermi 6g, Squama Manis 8g, each 6g of Radix Clematidis, Semen Coicis 19g, Lignum Sappan 6g, Radix Glycyrrhizae 8g.
Above-mentioned dosage is 1 dose.Every day 1 dose, it is decocted in water for oral dose, sooner or later sub-service.
The Chinese medicine composition of the present invention has been carried out clinical pharrnacokinetics test, and Details as Follows:
1 clinical data
1.1 physical data
The various operation of 6O example occurs lumbago patient after epidural anesthesia in l week, row general surgical operation 20 example, orthopaedics hands in 60 example patients Patient 33 example, urological surgery person 7 example.Do not find organic disease on inspection.It is randomly divided into treatment by Chinese herbs group 30 of the present invention Example and western medicine group 30 example.Male 17 examples in treatment group, female 13 example, age 24～58 years old, average out to (34.6 ± 1.5) year；Right According to 14 examples male in group, female 16 example；Age 23～59 years old, average out to (34.2 ± 1.4) year.Two groups the age, sex, the state of an illness, The aspect no significant difference such as Operative category, have comparability (P > 0.05).
1.2 inclusive criteria
There is lumbago in 1 week after epidural anesthesia in the various operations such as orthopaedics, department of general surgery, Urology Surgery；Preoperative medical history without lumbago； Age >=l8 year；Non-anemia of pregnant woman or women breast-feeding their children.
1.3 exclusion standard
The cognitive dysfunction person of impact test compliance；There is hematological abnormalities person；Previously there is lumbago medical history；There is cancer medical history Or other chronic diseases control gastrointestinal disease patient；Preoperative planning Aspartate aminotransferase (AST), alanine aminotransferase (ALT) Exception person, serum creatinine or urea nitrogen levels Upper Limit of Normal Value >=1.5 times person；Following medicine there is allergy medical history person, including appointing What a kind of NSAIDS, COX mono-inhibitor 2, sulfa drugs, opioid drug or have crossing with the medicine of use in this research The analgesic of quick reaction；Other analgesics of preoperative application；Epidural puncture is difficult or the case of repeated multiple times puncture (more than 3 times).
2 methods
2.1 GP TH Chinese drug-treated group give the Chinese medicine composition of the embodiment of the present invention 1.Every day 1 dose, decocting, point twice clothes of morning and evening. Matched group gives tramadol 100mg intramuscular injection.Two groups equal 4 weeks is 1 course for the treatment of, observes 1 course for the treatment of.
2.2 observation indexs (1) pain light and heavy degree: use pain visual imitation assessment (VAS) method；(2) untoward reaction.
2.3 statistical procedures
Using SPSS17.0 statistical software to carry out statistical disposition, enumeration data uses χ2Inspection；Measurement data represents with (x ± s), Use t inspection, statistically significant with P < 0.05 for difference.
3 results
" Chinese medical disease Standardization of diagnosis and curative effect " evaluation curative effect that 3.1 criterions of therapeutical effect are formulated according to State Administration of Traditional Chinese Medicine.
3.2 liang of group Clinical efficacy comparison treatment groups cure 18 examples, improvement lO example, the most 2 examples, total effective rate 93.3%；Matched group Cure 8 examples, improvement l5 example, the most 7 examples, total effective rate 76.6%.Two groups of Clinical efficacy comparison differences are statistically significant (P<0.05)。
Before and after 3.3 liang of group patient treatments, VAS marks to compare and is shown in Table 1.
Before and after 1 liang of table group patient treatment, (x ± s divides) is compared in VAS scoring
Group n Before treatment After treatment
Matched group 30 6.51±1.41 4.18±1.82*
Treatment group 30 6.79±1.21 3.40±1.42*△
* P < 0.05 with this group before treatment；Compare with after treatment of control group△P<0.05。
3.4 liang of group untoward reaction situations
Treatment by Chinese herbs group patient of the present invention has no adverse reaction, and matched group patient has 6 examples dizziness, the symptom such as feel sick occur, slow after drug withdrawal Solve.

Claims (3)

1. treat a Chinese medicine composition for epidural anesthesia Lumbar pain after operation, be made up of the Chinese medicine of following weight portion:
Radix Seu Caulis Rhaphidophorae Decursivae 11-19 part, Ramulus Cinnamomi 3-7 part, Ramulus Mori 6-14 part, Caulis et Folium Achyranthis bidentatae 4-8 part, Caulis Spatholobi 6-14 part, deep Grass 6-14 part, Herba Lycopodii 6-14 part, Rhizoma Sparganii 6-14 part, Radix Salviae Miltiorrhizae 6-14 part, Caulis Trachelospermi 6-14 part, Squama Manis 4-8 part, Radix Clematidis each 6-14 part, Semen Coicis 11-19 part, Lignum Sappan 6-10 part, Radix Glycyrrhizae 4-8 part.
The Chinese medicine composition for the treatment of epidural anesthesia Lumbar pain after operation the most according to claim 2, it is characterised in that by following weight The Chinese medicine composition of part:
Radix Seu Caulis Rhaphidophorae Decursivae 13-17 part, Ramulus Cinnamomi 4-6 part, Ramulus Mori 8-12 part, Caulis et Folium Achyranthis bidentatae 5-7 part, Caulis Spatholobi 8-12 part, deep Grass 8-12 part, Herba Lycopodii 8-12 part, Rhizoma Sparganii 8-12 part, Radix Salviae Miltiorrhizae 8-12 part, Caulis Trachelospermi 8-12 part, Squama Manis 5-7 part, Radix Clematidis each 8-12 part, Semen Coicis 13-17 part, Lignum Sappan 7-9 part, Radix Glycyrrhizae 5-7 part.
The Chinese medicine composition for the treatment of epidural anesthesia Lumbar pain after operation the most according to claim 2, it is characterised in that by following weight The Chinese medicine composition of part:
Radix Seu Caulis Rhaphidophorae Decursivae 15 parts, 5 parts of bavin osmanthus, Ramulus Mori 10 parts, Caulis et Folium Achyranthis bidentatae 6 parts, Caulis Spatholobi 10 parts, Herba speranskiae tuberculatae 10 parts, stretch Muscle grass 10 parts, Rhizoma Sparganii 10 parts, Radix Salviae Miltiorrhizae 10 parts, Caulis Trachelospermi 10 parts, Squama Manis 6 parts, each 10 parts of Radix Clematidis, Semen Coicis 15 parts, Lignum Sappan 8 parts, 6 parts of Radix Glycyrrhizae.
CN201610480449.1A 2016-06-27 2016-06-27 Traditional Chinese medicine composition for treating lumbar pain after epidural anesthesia Pending CN105943973A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111773295A (en) * 2020-08-26 2020-10-16 广西中医药大学第一附属医院 Traditional Chinese medicine composition for treating arthritis, sea salt bag and preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169185A (en) * 2015-10-19 2015-12-23 济南邦文医药科技有限公司 Traditional Chinese medicinal composition for treating kidney-asthenia cold-dampness type gynecological postoperative lumbar pain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169185A (en) * 2015-10-19 2015-12-23 济南邦文医药科技有限公司 Traditional Chinese medicinal composition for treating kidney-asthenia cold-dampness type gynecological postoperative lumbar pain

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111773295A (en) * 2020-08-26 2020-10-16 广西中医药大学第一附属医院 Traditional Chinese medicine composition for treating arthritis, sea salt bag and preparation method and application thereof

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Application publication date: 20160921