CN103495050B - Chinese medicinal composition for treating blood-heat stasis type acne - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating blood-heat stasis type acne. The Chinese medicinal composition for treating the blood-heat stasis type acne is prepared from obedient plant, south isatis root, three-vein clearweed, natural indigo, achyranthes aspera, red paeony root, polygonum cuspidatum, lalang grass rhizome, pagodatree pod and red sandalwood. The Chinese medicinal composition can be used for treating the blood-heat stasis type acne clinically.

Description

A kind of Chinese medicine composition for the treatment of heat in blood stasis type acne

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of heat in blood stasis type acne.

Background technology

The traditional Chinese medical science claims acne to be acne, i.e. the face institute little pimple shape projection of giving birth to, and secretly, have sufferings sense, can extrude white or suppurative liquid, cicatrix and pigmentation can appear to color in disease damage place pachylosis, especially common with adolescence.Doctor trained in Western medicine thinks a kind of relevant hair follicle, sebaceous gland chronic inflammatory skin disease of lacking of proper care with gonadal Function.The successive dynasties traditional Chinese medical science all has description to primary disease: have early than in Huangdi's Internal Classics: " all sufferings skin ulcers all belong to the heart, and sweating is shown in that wet is raw furuncle and prickly heat ", also record: " this card is formed by lung meridian heat in blood in " Yizong Jinjian surgery heart method gist rosacea caused by lung-wind ".Often send out in face nose, play broken pimple, shape such as broomcorn millet is considered to be worth doing, and red complexion swells and ache, and breaks out white lead juice, with the passing of time all becomes white scales, and shape is as Semen Panici miliacei white scales." clinical middle some women often in premenstrual aggravation, through after alleviate or disappear.Treated heat in blood stasis type acne in the past and commonly use single western medicine therapy, but effect is not satisfactory, the long-term practice through inventor draws, Chinese medicine is controlled heat in blood stasis type acne and had better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment heat in blood stasis type acne of human non-toxic's side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Dracocephalum moldabium, Rhizoma Et Radix Baphicacanthis Cusiae, large cold water fiber crops, Indigo Naturalis, Radix Achyranthis, Radix Paeoniae Rubra, Rhizoma Polygoni Cuspidati, Rhizoma Imperatae, the Fructus Sophorae, Lignum pterocarpi indici according to certain compatibility requirement, process is processed into.

Prepare Chinese medicine composition of the present invention and make Dracocephalum moldabium 30-40 part, Rhizoma Et Radix Baphicacanthis Cusiae 20-30 part, large cold water fiber crops 20-30 part, Indigo Naturalis 15-25 part, Radix Achyranthis 15-25 part, Radix Paeoniae Rubra 15-25 part, Rhizoma Polygoni Cuspidati 15-25 part, Rhizoma Imperatae 15-25 part, Fructus Sophorae 10-20 part, Lignum pterocarpi indici 3-5 part by following raw material medicaments.

Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: Dracocephalum moldabium 35 parts, Rhizoma Et Radix Baphicacanthis Cusiae 25 parts, greatly cold water fiber crops 25 parts, Indigo Naturalis 20 parts, Radix Achyranthis 20 parts, Radix Paeoniae Rubra 20 parts, Rhizoma Polygoni Cuspidati 20 parts, Rhizoma Imperatae 20 parts, the Fructus Sophorae 15 parts, 4 parts, Lignum pterocarpi indici.The pharmacological action of Chinese medicine of the present invention is as follows:

Dracocephalum moldabium: pungent, bitter, cool.Wind and heat dispersing, removing pathogenic heat from blood and toxic substance from the body.Clinical in headache of catching a cold, laryngopharynx swelling and pain, cough, jaundice, the diseases such as dysentery.

Rhizoma Et Radix Baphicacanthis Cusiae: bitter, cold.GUIXIN, liver, stomach warp.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.For maculae caused by violent heat pathogen, high heat headache, erysipelas, mumps, viral hepatitis, popular pneumonia, the diseases such as flu.

Large cold water fiber crops: light, puckery, flat.Stasis-dispelling and pain-killing, heat-clearing and toxic substances removing.Clinical in traumatic injury, fracture, innominate toxic swelling, erysipelas, the diseases such as ulcer sores.

Indigo Naturalis: salty, cold.Return lung, liver, stomach warp.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, the diseases such as arresting convulsion.

Radix Achyranthis: sweet, micro-hardship, micro-acid, cold in nature.Return liver, kidney channel.Blood circulation promoting and blood stasis dispelling, eliminating fire and detoxication, inducing diuresis for treating stranguria syndrome.For amenorrhea, traumatic injury, Fengshi Guanjie pain, dysentery, diphtheria, laryngopharynx swelling and pain, the diseases such as edema.

Radix Paeoniae Rubra: bitter, be slightly cold.Return liver, spleen channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, discharging fresh blood stool, carbuncle skin infection etc.

Rhizoma Polygoni Cuspidati: bitter, cold.Return liver, gallbladder, lung meridian.Promoting the function of the gallbladder to alleviate jaundice, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, expelling phlegm for arresting cough.For jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, carbuncle sore tumefacting virus, venom, cough due to lung-heat etc.

Rhizoma Imperatae: sweet, cold.Return stomach, lung, the heart, urinary bladder channel.Cooling blood for hemostasis, clearing away heat and promoting production of body fluid, inducing diuresis for treating stranguria syndrome.Clinical in jaundice, heat in blood is hemorrhage, calentura excessive thirst, gastric heat vomiting, dyspnea and cough due to lung-heat, the puckery pain of dribbling urination, the diseases such as edema.

The Fructus Sophorae: bitter, cold.Cooling blood for hemostasis, liver heat removing and eyesight improving.For bleeding hemorrhoids, discharging fresh blood stool, dysentery, metrorrhagia, stranguria with blood, heat in blood tells nosebleed, poliosis, liver-heat conjunctival congestion, the disease such as to have a dizzy spell.

Lignum pterocarpi indici: become, put down.Return Liver Channel.Blood stasis dispelling and battalion, hemostasis analgesic therapy, removing toxic substances and promoting subsidence of swelling.Clinical in headache, cardiac and abdominal pain, lochiorrhea, urine leaching pain, pathogenic wind toxic carbuncle, incised wound is hemorrhage waits disease.

In the many evil intrusive bodies by wind heat, summer-heat of person caused by exopathogenic factor, involve blood system, so that heat in blood is strongly fragrant in local, sends out as acne.Person caused by endogenous cause of ill mostly is ferritic sun heat and partially contains, and nutrient blood is partial heat day by day, and heat in blood is stopped up outward, stagnation of QI-blood, accumulates resistance skin and sends out primary disease; Or because of the product of the pungent delicious food of surfeit, lung stomach accumulated heat, the lung and the large intestine being interior-exteriorly related, constipation with dry stool causes FU QI being obstructed, accumulates heat-transformation of a specified duration, and steam in lung on multiple, characteristic of fire being flaring up, with the passing of time edema caused by disorder of QI pathogenic heat, gos deep into nutrient blood, follows through upper smoked, blood with heat row, on stop up in breast face; Or cure the wound by feelings will, the edema caused by disorder of QI stasis of blood is stagnant, with the passing of time heat-transformation, caused by the nutrient blood of heat volt.Control should heat clearing and blood cooling and battalion blood stasis dispelling be main.Dracocephalum moldabium wind and heat dispersing, removing pathogenic heat from blood and toxic substance from the body, Rhizoma Et Radix Baphicacanthis Cusiae heat-clearing and toxic substances removing, removing heat from blood detumescence, large cold water fiber crops blood stasis dispelling, heat-clearing and toxic substances removing in the present invention, for monarch drug, Indigo Naturalis heat-clearing and toxic substances removing, removing heat from blood, Radix Achyranthis blood stasis dispelling, eliminating fire and detoxication, Radix Paeoniae Rubra, Rhizoma Polygoni Cuspidati clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, Rhizoma Imperatae, Fructus Sophorae removing heat from blood, heat clearing away, Lignum pterocarpi indici blood stasis dispelling and battalion, removing toxic substances and promoting subsidence of swelling.Find to have unique curative effect to heat in blood stasis type acne through clinical practice, all medicines are played heat-clearing and toxic substances removing, removing heat from blood detumescence altogether and are sought effect of blood stasis dispelling, reach the object for the treatment of heat in blood stasis type acne.

Chinese medicine composition of the present invention was in 2006 to 2012 the routine patients of clinical observation heat in blood stasis type acne 55, and clinical report is as follows:

1, physical data

In 55 routine patients, in age 17-30 year, the course of disease is many at 3 months to 2 years, 23 years old mean age.

2, diagnostic criteria

" Chinese medical disease Standardization of diagnosis and curative effect " that 2.1 diagnosis basis State Administration of Traditional Chinese Medicines issue:

1. the initial stage presents the red papules of grain of rice size at follicular orifice, also can develop into pustule, and after this can form Whiteheads or the blackhead of scleroma sample, several cases can form scleroma property cyst;

2. be mainly in young men and women's adolescence, be distributed in face and chest and back, often with seborrhea;

3. have the thick greasy or exopathogen of eating and drinking without temperance, surfeit delicious food etc. to bring out more;

4. women is many with menoxenia.

Clinical manifestation: pimple is many with mouth and nose and two glabellas, facial hectic fever is obvious, and women increases the weight of with menses skin lesion of rising, through after alleviate, red tongue, thready and rapid pulse etc.

2.2 inclusive criterias:

1. 11 ~ 30 years old age; 2. the diagnostic criteria of homeliness type heat in blood stasis type acne is met; 3. observe in first 4 weeks not with the Chinese and western drugs relevant with primary disease; 4. patient agrees to participate in voluntarily, and can coordinate clinical observation.

2.3 exclusion standards:

1. known to Viaminate allergy sufferers; 2. first 2 weeks of the examination once anti-heat in blood stasis type acne medicine person such as external corticosteroid hormone, antibiotic is entered; 3. enter to try first 4 weeks once oral corticosteroids hormone, gonadal hormone, antibiotic medicine persons; 4. gestation or women breast-feeding their children; 5. the occupational heat in blood stasis type acne caused by chemical substance, drug-induced heat in blood stasis type acne.

3, Therapeutic Method

3.1 prescriptions: Dracocephalum moldabium 35g, Rhizoma Et Radix Baphicacanthis Cusiae 25g, large cold water fiber crops 25g, Indigo Naturalis 20g, Radix Achyranthis 20g, Radix Paeoniae Rubra 20g, Rhizoma Polygoni Cuspidati 20g, Rhizoma Imperatae 20g, Fructus Sophorae 15g, Lignum pterocarpi indici 4g.

3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 7 days was 1 course for the treatment of.

4, therapeutic outcome:

4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":

Recovery from illness: skin lesion extinction rate >=95%, or only leave over a little pigmentation, transference cure;

Effective: skin lesion major part disappears, extinction rate 70% ~ 95%, symptom obviously alleviates;

Effective: skin lesion partial remission, extinction rate 50% ~ 70%, symptom is improved;

Invalid: skin lesion disappears not obvious or increases the weight of, extinction rate < 50%, symptom has no change.

4.2 results: in 55 routine patients, clinical cure 32 example (58.2%), effective 11 examples (20%), 10 examples that take a turn for the better (18.2%), invalid 2 examples (3.6%), total effective rate is 96.4%.

Model case

1, Zhang, man, 21 years old, skin oil and fat secretion was vigorous, and the intensive multiple pimple pustule of Face and cheek, forehead, lower jaw also have a little lesser tubercle, suffer from constipation simultaneously, the symptoms such as mouth and nose drying, halitosis.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after half a year.

2, Lee, female, 18 years old, facial oiliness, corse sweat pore, face was except nose and eye, and equal red color visible or pale red pimple, can extrude white lead color grease, and menses skin lesion of rising increases the weight of.Take medicine of the present invention, every day 1 dose, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after 1 year.

3, grandson, man, 23 years old, suffer from acne existing for many years, Face and cheek acne merged in flakes, and color is red, and there is pustule tip, red tongue, yellow and thin fur, and floating-rolling pulse number, with symptoms such as constipation.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after half a year.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.

Embodiment 1, a kind of Chinese medicine composition for the treatment of heat in blood stasis type acne is made up of Dracocephalum moldabium 30g, Rhizoma Et Radix Baphicacanthis Cusiae 20g, large cold water fiber crops 20g, Indigo Naturalis 15g, Radix Achyranthis 15g, Radix Paeoniae Rubra 15g, Rhizoma Polygoni Cuspidati 15g, Rhizoma Imperatae 15g, Fructus Sophorae 10g, Lignum pterocarpi indici 3g.

Embodiment 2, a kind of Chinese medicine composition for the treatment of heat in blood stasis type acne is made up of Dracocephalum moldabium 35g, Rhizoma Et Radix Baphicacanthis Cusiae 25g, large cold water fiber crops 25g, Indigo Naturalis 20g, Radix Achyranthis 20g, Radix Paeoniae Rubra 20g, Rhizoma Polygoni Cuspidati 20g, Rhizoma Imperatae 20g, Fructus Sophorae 15g, Lignum pterocarpi indici 4g.

Embodiment 3, a kind of Chinese medicine composition for the treatment of heat in blood stasis type acne is made up of Dracocephalum moldabium 40g, Rhizoma Et Radix Baphicacanthis Cusiae 30g, large cold water fiber crops 30g, Indigo Naturalis 25g, Radix Achyranthis 25g, Radix Paeoniae Rubra 25g, Rhizoma Polygoni Cuspidati 25g, Rhizoma Imperatae 25g, Fructus Sophorae 20g, Lignum pterocarpi indici 5g.

Claims (2)

1. treat a Chinese medicine composition for heat in blood stasis type acne, it is characterized in that it is made up of following raw material medicaments:

Dracocephalum moldabium 30-40 part, Rhizoma Et Radix Baphicacanthis Cusiae 20-30 part, large cold water fiber crops 20-30 part, Indigo Naturalis 15-25 part, Radix Achyranthis 15-25 part, Radix Paeoniae Rubra 15-25 part, Rhizoma Polygoni Cuspidati 15-25 part, Rhizoma Imperatae 15-25 part, Fructus Sophorae 10-20 part, Lignum pterocarpi indici 3-5 part.

2. Chinese medicine composition according to claim 1, is characterized in that it is made up of following raw material medicaments:

Dracocephalum moldabium 35 parts, Rhizoma Et Radix Baphicacanthis Cusiae 25 parts, greatly cold water fiber crops 25 parts, Indigo Naturalis 20 parts, Radix Achyranthis 20 parts, Radix Paeoniae Rubra 20 parts, Rhizoma Polygoni Cuspidati 20 parts, Rhizoma Imperatae 20 parts, the Fructus Sophorae 15 parts, 4 parts, Lignum pterocarpi indici.