CN106860717A - It is a kind of to treat infertile medicine - Google Patents

It is a kind of to treat infertile medicine Download PDF

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CN106860717A
CN106860717A CN201510910115.9A CN201510910115A CN106860717A CN 106860717 A CN106860717 A CN 106860717A CN 201510910115 A CN201510910115 A CN 201510910115A CN 106860717 A CN106860717 A CN 106860717A
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parts
infertile
medicine
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root
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李中利
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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Abstract

Infertile medicine is treated the invention discloses a kind of, is included according to the raw material of weight portion：Fennel seeds 3-8 parts, corydalis tuber 5-10 parts, myrrh 3-8 parts, Radix Angelicae Sinensis 5-10 parts, Ligusticum wallichii 5-10 parts, Chinese cassia tree 8-15 parts, excrementum pteropi 1-3 parts, motherwort 3-8 parts, rhizoma cyperi 3-8 parts, spina date seed 8-15 parts, fushen 1-3 parts, Radix Codonopsis 1-3 parts, Fructus Corni 5-10 parts, root of large-flowered skullcap 3-8 parts, schizonepeta 1-5 parts, capsule of weeping forsythia 8-15 parts.The Chinese medicine of prescription selection of the invention all has promoting the circulation of qi, promoting blood circulation effect, treats infertile effect substantially, can strengthen human immunological competence, especially has effective to infertile caused by the inferior health reason such as uncomfortable.Cure rate of the invention up to 92%, efficient 99%.

Description

It is a kind of to treat infertile medicine
Technical field
It is specifically a kind of to treat infertile medicine the present invention relates to field of medicaments.
Background technology
Infertile medical definition did not took any contraceptives for 1 year, and sexual life is normally without successful pregnancy.It is broadly divided into primary infertility and secondary infertility.Primary infertility is never to become pregnant；Secondary infertility is after being once pregnant and infertile.Primary etiological diagnosis is successively：Ovulation failure, dysspermatism, oviduct abnormality, the infertile of unknown cause, endometriosis and other such as immunologys are infertile.Other factor is uterine neck factor, including accounts for all cervical stenosises of the uterine neck factor more than 5%.Female acyesis are main with ovulation failure, Tubal factor, and based on endometrium receptivity exception, male infertility is mainly that production of sperm is abnormal and the smart obstacle of row.At present, the medicine for the treatment of infertility is various, is totally divided into Western medicine and the class of Chinese medicine two, and Western medicine mainly based on antibiotic, coordinates operation, but cannot remove its root, also many Chinese medicines, but effect is unsatisfactory mostly.
The content of the invention
It is an object of the invention to provide a kind of infertile medicine of the good treatment of promoting the circulation of qi, promoting blood circulation effect, effect, to solve the problems, such as to be proposed in above-mentioned background technology.
To achieve the above object, the present invention provides following technical scheme：
It is a kind of to treat infertile medicine, include according to the raw material of weight portion：Fennel seeds 3-8 parts, corydalis tuber 5-10 parts, myrrh 3-8 parts, Radix Angelicae Sinensis 5-10 parts, Ligusticum wallichii 5-10 parts, Chinese cassia tree 8-15 parts, excrementum pteropi 1-3 parts, motherwort 3-8 parts, rhizoma cyperi 3-8 parts, spina date seed 8-15 parts, fushen 1-3 parts, Radix Codonopsis 1-3 parts, Fructus Corni 5-10 parts, root of large-flowered skullcap 3-8 parts, schizonepeta 1-5 parts, capsule of weeping forsythia 8-15 parts.
As further scheme of the invention：The infertile medicine of the treatment, includes according to the raw material of weight portion：Fennel seeds 4-7 parts, corydalis tuber 6-9 parts, myrrh 4-7 parts, Radix Angelicae Sinensis 6-9 parts, Ligusticum wallichii 6-9 parts, Chinese cassia tree 10-13 parts, 2 parts of excrementum pteropi, motherwort 4-6 parts, rhizoma cyperi 4-6 parts, spina date seed 10-12 parts, 2 parts of fushen, 2 parts, Fructus Corni 7-9 parts, root of large-flowered skullcap 5-7 parts, schizonepeta 2-4 parts, capsule of weeping forsythia 10-12 parts of Radix Codonopsis.
Fennel seeds yang-tonifying cold dispelling, qi-regulating appetizing, preventing or arresting vomiting in the present invention.Main Function is stomach invigorating, and gentle stimulation is played to stomach and intestine, can reduce flatulence.Additionally, clinical observation thinks that fennel seeds have certain analgesic activity, no matter to gastrointestinal convulsion pain or muscle injury sprain bitterly, have certain mitigation.
Corydalis tuber is used for each portion's qi depression to blood stasis of whole body pain, and dysmenorrhoea, Amenorrhea, abdominal mass, postpartum stasis, injury from falling down, hernia is had a pain.
Myrrh dissipates blood and relieving pain, detumescence and promoting granulation.Cure mainly：Ulcer sore pain, trusted subordinate, all pains of muscles and bones damage blood, and external application can sore
Chinese angelica blood supplementing, promoting blood circulation, menstruation regulating, moisturize, laxation.Cure mainly：Irregular menstruation, the deficiency of blood or blood stasis is through closing, dysmenorrhoea uterine bleeding, traumatic injury, ulcer sore pain, arthralgia pain due to rheumatism, the deficiency of blood such as just close at the disease.
Ligusticum wallichii blood-activating and qi-promoting, for irregular menstruation such as delayed menstrual cycle limit, dysmenorrhoea, the Amenorrhea of stagnation of QI and blood, there is promoting blood circulation, promoting qi circulation and relieving pain, therefore preceding person " gas medicine in blood ".Often it is use with Radix Angelicae Sinensis mutual reinforcement between, to strengthen promoting blood circulation, the row stasis of blood, the effect of analgesic.
Chinese cassia tree warming spleen and stomach for dispelling cold, mainly expansion of blood vessels and make blood circulation vigorous, and have certain perspiration.Due to that can stimulate circulation, therefore help to strengthen the effect of other medicines.
Excrementum pteropi dissipates the stasis of blood, promoting circulation of blood, analgesic.Cure mainly：The diseases such as irregular menstruation, dysmenorrhoea, postpartum stasis of blood, epigastric pain, enterocele pain.
Motherwort promoting blood circulation for regulating menstruation, promoting circulation of blood dissipate the stasis of blood, are uterine stimulant.Shrink uterus：The convergent force and tonicity of uterus muscle can be significantly increased, acts on similar to safflower and posterior pituitary hormone, but power is weaker.Live part is leaf portion.Decoction effect is better than tincture.
Rhizoma cyperi controls irregular menstruation, cramp.Witness has stagnation of QI due to depression of the liver, with psychoneural factor（Such as it is in a very depressed state or irascible, nervous）Relevant menstrual pain is preferably.Siwu Tang can be matched somebody with somebody with rhizoma cyperi, or add the root of three-nerved spicebush, corydalis tuber.Such as belong to through carrying out the later stage, the underbelly cold of insufficiency type has a pain, can be with rhizoma cyperi with Radix Angelicae Sinensis, Ligusticum wallichii, the bark of eucommia, folium artemisiae argyi etc., side's such as rhizoma cyperi rhizome of chuanxiong returns soup, can menstruation regulating, and can relieve pain.
Spina date seed is sweet, acid, mild-natured.Conscience can be nourished, is calmed the nerves, arrest sweating.
Fushen's calming heart, calms the nerves, Li Shui.Palpitation with fear of having a guilty conscience is controlled, forgetful, insomnia, frightened epilepsy, difficult urination.
Radix Codonopsis is mild-natured, sweet, hasTonifying middle-Jiao and Qi、Invigorating the spleenThe effect of beneficial lung, anticancer, step-down, anti anoxia, anti-aging, body immunity can also be strengthened, improve superoxide dismutase activity, enhancing eliminate free radical ability, with Gastrointestinal motility adjustment, antiulcer, gastric acid secretion inhibiting, reduce pepsin activity effect.Suitable for diseases such as spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, ulcer, anaemia, virtual asthma cough, Heat Diabetes.
Fructus Corni tonifies the liver and kidney；Convergence is solid de-.Cure mainly and have a dizzy spell；Deafness and tinnitus；Soreness and weakness of waist and knees；Emission and spermatorrhea；Frequent urination；Incessant sweating due to debility；Woman uterine bleeding；Heat Diabetes；Warm liver kidney tonifying, except a wind cutting, only menorrhalgia, punish-old people's frequent micturition.
It is root of large-flowered skullcap bitter, cold in nature, there are heat-clearing and damp-drying drug, purging intense heatRemoving toxic substances、Hemostasis、It is antiabortiveThe effects such as.Cure mainly warm heat disease, the infection of the upper respiratory tract,Lung heatCough,It is damp and hotJaundice,Pneumonia、Dysentery、Hemoptysis, hot eyes,Fetal irritability, hypertension,Carbuncle swellsThe diseases such as furuncle sore.The clinical antibiotic property of the root of large-flowered skullcap is better than the coptis, and does not develop immunity to drugs.
Schizonepeta wind-dispelling；Inducing diaphoresis；Promoting eruption；Hemostasis.Main cold, fever；Headache；Eye itching；Cough；Abscess of throat；Measles；Carbuncle swells；Sore scabies；Bleeding from five sense organs or subcutaneous tissue；Spit blood；Have blood in stool；Uterine bleeding；Postpartum anemic fainting.For catching a cold, headache, measles, rubella, sore from the beginning of.Fry charcoal treating hematochezia, uterine bleeding, postpartum anemic fainting.Inducing diaphoresis dissipates wind,Promoting eruption, disappear sore, hemostasis.For catching a cold,MeaslesHair is not smooth thoroughly, have blood in stool, uterine bleeding, nosebleed epistaxis.
Capsule of weeping forsythia heat-clearing, removing toxic substances, dissipating bind, detumescence.Control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.
Compared with prior art, the beneficial effects of the invention are as follows：
The Chinese medicine of prescription selection of the invention all has promoting the circulation of qi, promoting blood circulation effect, treats infertile effect substantially, can strengthen human immunological competence, especially has effective to infertile caused by the inferior health reason such as uncomfortable.Cure rate of the invention up to 92%, efficient 99%.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made belongs to the scope of protection of the invention.
Embodiment 1
It is a kind of to treat infertile medicine in the embodiment of the present invention, include according to the raw material of weight portion：3 parts of fennel seeds, 5 parts of corydalis tuber, 3 parts of myrrh, 5 parts of Radix Angelicae Sinensis, 5 parts of Ligusticum wallichii, 8 parts of Chinese cassia tree, 1 part of excrementum pteropi, 3 parts of motherwort, 3 parts of rhizoma cyperi, 8 parts of spina date seed, 1 part of fushen, 1 part of Radix Codonopsis, 5 parts of Fructus Corni, 3 parts of the root of large-flowered skullcap, 1 part of schizonepeta, 8 parts of the capsule of weeping forsythia.
Embodiment 2
It is a kind of to treat infertile medicine in the embodiment of the present invention, include according to the raw material of weight portion：8 parts of fennel seeds, 10 parts of corydalis tuber, 8 parts of myrrh, 10 parts of Radix Angelicae Sinensis, 10 parts of Ligusticum wallichii, 15 parts of Chinese cassia tree, 3 parts of excrementum pteropi, 8 parts of motherwort, 8 parts of rhizoma cyperi, 15 parts of spina date seed, 3 parts of fushen, 3 parts of Radix Codonopsis, 10 parts of Fructus Corni, 8 parts of the root of large-flowered skullcap, 5 parts of schizonepeta, 15 parts of the capsule of weeping forsythia.
Embodiment 3
It is a kind of to treat infertile medicine in the embodiment of the present invention, include according to the raw material of weight portion：4 parts of fennel seeds, 6 parts of corydalis tuber, 4 parts of myrrh, 6 parts of Radix Angelicae Sinensis, 6 parts of Ligusticum wallichii, 10 parts of Chinese cassia tree, 2 parts of excrementum pteropi, 4 parts of motherwort, 4 parts of rhizoma cyperi, 10 parts of spina date seed, 2 parts of fushen, 2 parts of Radix Codonopsis, 7 parts of Fructus Corni, 5 parts of the root of large-flowered skullcap, 2 parts of schizonepeta, 10 parts of the capsule of weeping forsythia.
Embodiment 4
It is a kind of to treat infertile medicine in the embodiment of the present invention, include according to the raw material of weight portion：7 parts of fennel seeds, 9 parts of corydalis tuber, 7 parts of myrrh, 9 parts of Radix Angelicae Sinensis, 9 parts of Ligusticum wallichii, 13 parts of Chinese cassia tree, 2 parts of excrementum pteropi, 6 parts of motherwort, 6 parts of rhizoma cyperi, 12 parts of spina date seed, 2 parts of fushen, 2 parts of Radix Codonopsis, 9 parts of Fructus Corni, 7 parts of the root of large-flowered skullcap, 4 parts of schizonepeta, 12 parts of the capsule of weeping forsythia.
Taken by after being added water to cook after each raw material in above-described embodiment is mixed.
Embodiment 5
The acute toxicity testing of medicine of the present invention：
Experiment is research object with ICR small white mouses, takes weight range 20-25g, quantity 30, male mouse 15, raettin 15, source medical courses in general institute of Zhejiang Province, the animal quality quality certification：The dynamic card word 11-007 in Zhejiang.Small white mouse health, is fed, 25 DEG C ± 3 DEG C of room temperature, relative humidity 55%-60% using synthetic diet.Choose 10 small white mouses and do trial test, bowel lavage is carried out with the strength solution of medicine of the present invention 50%, medicine is given according to the ratio of 50ml/kg, dosage equivalent to 25g/kg, there is not animal dead phenomenon equivalent to 120g/kg in equivalent crude drug, illustrates that median lethal dose is not reached much.Remaining 20 small white mouses are formally tested.It is implemented to take food within 24 hours, then bowel lavage is carried out according to 50% strength solution, equivalent to 120g/kg, small white mouse is without any discomfort situation for dosage.It is observed in subsequent week age, does not also occur exception without there is lethal cases, diet, activity, hair, stool and urine of small white mouse etc..There is not substantially increase in Mouse Weight.Small white mouse is put to death, its internal organ is visually observed, to see exception.The perfusion amount of small white mouse is 25g/kg (120g/kg crude drugs), with normal person's 60kg body weight, is taken daily 2 times, each 3g is calculated, the dosage of people is 0.1g/kg, and small white mouse consumption is 250 times of people, illustrates that the medicine of the invention is used without Acute Toxicity human body.
The clinical test of embodiment 6：
Below by way of clinical observation on the therapeutic effect experiment, the beneficial effect of medicine of the present invention is expanded on further.
First, physical data：
By 5 years clinical application practices, out-patient 100, wherein 25-30 Sui patient 40,30-35 Sui 40,35-40 Sui 20 are accepted for medical treatment.
2nd, diagnostic criteria：
A renal deficiency types：Infertile after marriage or post-abortion is infertile, and delayed menstrual cycle amount is few, or dilute hair amenorrhoea, and soreness of waist and knee, sexual desire declines, and vagina is relatively interfered, and frequent urination at night, underbelly is cold.
B stasis of blood types：Infertile after marriage or post-abortion is infertile, delayed menstrual cycle dysmenorrhoea, dim through color, and menostaxis or dysmenorrhoea is more violent.
C wet types：Infertile after marriage or post-abortion is infertile, delayed menstrual cycle dilute hair or amenorrhoea, and leukorrhea amount is more, and body is fat, and lusterless complexion or impractical, abundant expectoration uncomfortable in chest, tongue is weak is fat, and tongue is greasy in vain, veins is sliding.
D cold moulds：Infertile after marriage or post-abortion is infertile, depressed joyless, and anxiously, happiness is sighed, and is easily cried, and uncomfortable in chest, after menstruation shifts to an earlier date mistake, tongue is dim red, and tongue is thin white, small and wiry pulse.
3rd, treatment method：
Three times a day, each 100-200 milliliters, 20 days is a course for the treatment of, takes medicine continuously three courses for the treatment of.
4th, efficacy assessment standard：
Cure：Sign symptom is obviously improved, and the soreness of waist, pain disappear, and youthful vigor increases, and gestation pregnancy is normal.
It is effective：Frigidity phenomenon disappears, eumenorrhea, and dysmenorrhoea mitigates, and ovulation is normal.
It is invalid：Pathological symptom is without substantially change.
5th, therapeutic effect：
Take three courses for the treatment of of this medicine, cure 92, effective 7, invalid 1, cure rate up to 92%, efficient 99%.
1st, Wang, female 36 years old, is married 10 years with husband, and infertility, hospital diagnosis pelvic infecton is not pregnant yet after taking anti-inflammatory drugs.Its course for the treatment of of 3 months is provided by the medicine of embodiment 2 afterwards, Wang is pregnant in the same year, the next girl of life.
2nd, Song, female 40 years old, marries 14 years with husband, is never pregnant, and sees all over each large hospital of knowing clearly, and is not in progress at all.Afterwards by the drug administration 4 months of embodiment 3, after have pregnancy sign, the next boy of life.
3rd, Liao, female is 25 years old, unmarried.Have a boyfriend, pregnancy is multiple, the multiple stream of people, after by checking, endometrium is thinning, it is impossible to provides fertilization egg implantation, causes infertile.The medicine of embodiment 4 is taken, 4 months doses of the course for the treatment of are given, is pregnant afterwards, the next girl of life.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, and without departing from the spirit or essential characteristics of the present invention, can in other specific forms realize the present invention.Therefore, no matter from the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is limited by appended claims rather than described above, it is intended that all changes fallen in the implication and scope of the equivalency of claim are included in the present invention.
In addition, it should be understood that, although the present specification is described in terms of embodiments, but not each implementation method only includes an independent technical scheme, this narrating mode of specification is only for clarity, those skilled in the art should using specification an as entirety, technical scheme in each embodiment can also through appropriately combined, formed it will be appreciated by those skilled in the art that other embodiment.

Claims (2)

1. it is a kind of to treat infertile medicine, it is characterised in that the raw material according to weight portion includes：Fennel seeds 3-8 parts, corydalis tuber 5-10 parts, myrrh 3-8 parts, Radix Angelicae Sinensis 5-10 parts, Ligusticum wallichii 5-10 parts, Chinese cassia tree 8-15 parts, excrementum pteropi 1-3 parts, motherwort 3-8 parts, rhizoma cyperi 3-8 parts, spina date seed 8-15 parts, fushen 1-3 parts, Radix Codonopsis 1-3 parts, Fructus Corni 5-10 parts, root of large-flowered skullcap 3-8 parts, schizonepeta 1-5 parts, capsule of weeping forsythia 8-15 parts.
2. it is according to claim 1 to treat infertile medicine, it is characterised in that the raw material according to weight portion includes：Fennel seeds 4-7 parts, corydalis tuber 6-9 parts, myrrh 4-7 parts, Radix Angelicae Sinensis 6-9 parts, Ligusticum wallichii 6-9 parts, Chinese cassia tree 10-13 parts, 2 parts of excrementum pteropi, motherwort 4-6 parts, rhizoma cyperi 4-6 parts, spina date seed 10-12 parts, 2 parts of fushen, 2 parts, Fructus Corni 7-9 parts, root of large-flowered skullcap 5-7 parts, schizonepeta 2-4 parts, capsule of weeping forsythia 10-12 parts of Radix Codonopsis.
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Application publication date: 20170620