CN109833417A - The composition and preparation method thereof for treating thyroiditis - Google Patents
The composition and preparation method thereof for treating thyroiditis Download PDFInfo
- Publication number
- CN109833417A CN109833417A CN201711199963.9A CN201711199963A CN109833417A CN 109833417 A CN109833417 A CN 109833417A CN 201711199963 A CN201711199963 A CN 201711199963A CN 109833417 A CN109833417 A CN 109833417A
- Authority
- CN
- China
- Prior art keywords
- parts
- thyroiditis
- campanulaceae
- dandelion
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of compositions and preparation method thereof for treating thyroiditis, it is made of the Chinese medicine material of following parts by weight: 16-20 parts of fritillaria thunbergii, 6-9 parts of campanulaceae, 8-10 parts of radix scrophulariae, 8-10 parts of bombyx batryticatus, 8-10 parts of Lasiosphaera fenzlii, 4-6 parts of dandelion, 10-12 parts of Prunella vulgaris, 4-6 parts of honeysuckle flower, 6-9 parts of Fructus Forsythiae, 6-9 parts of radix paeoniae rubra.With significant in efficacy, preparation is convenient, and patient compliance is good, the advantage having no toxic side effect, and is worth clinical expansion and application.
Description
[technical field]
The invention belongs to technical field of traditional Chinese medicine, and in particular to a kind of composition for treating thyroiditis and its preparation
Method.
[background technique]
Thyroid disease, age of onset 20-60 years old in the majority, and female middle-aged disease incidence is high, with change caused after virus infection
State reaction is related, with fever, thyroid gland position pain, Thyroid Gland Swell, subtracts etc. with hyperthyroidism, first as main clinical characteristics.In
Doctor thinks that this disease belongs to " goiter " scope.Ancient Times in China doctor thinks that the main pathogenesis of goiter is solidifying phlegm, the stagnation of the circulation of vital energy, the tired heap soil or fertilizer over and around the roots knot of blood in neck
Before.Part of patient is due to mental disorder pent-upization fire, fire consumption impairment of yin essence, so as to cause fire excess from yin deficiency pathological change.At the beginning of goiter
Phase more real examples, day prolonged illness can be changed into asthenic symptoms by real example, especially based on the deficiency of vital energy, the deficiency of Yin, to simulataneous insufficiency and excessive occur
Complicated disease.In conjunction with modern traditional Chinese medicine theory of development, from the angle for improving curative effect of medication, reducing side effect, by pair
Chinese medicine carries out Chinese materia medica preparation made from screening extraction and/or compatibility, shows unique advantage on treating this disease, can not only make
Clinical symptoms obtain rapid recovery, and substantially reduce recurrence rate, improve the quality of life of patient, are worth more deep
It is researched and developed.
At present for the treatment of thyroiditis, no matter home and abroad, mostly with hormone therapy on western medical treatment, as it is oral it is strong
Pine or application hydrogenation cortisone intravenous drip, what the fever of patient and Thyroid Neoplasms had after medication can control quickly.But
The state of an illness is easy exacerbation or goitre pain and develops to the other side from side during hormone decrement, and the course of disease is caused to extend.20%-
Disease relapse after 30% patient is discontinued.Hormone, which is used for a long time, there is also other side effects, such as moon shaped face, buffalo hump, sclerotin
Loose etc., there are also induce hypertension, diabetes, tuberculosis and Gastrointestinal ulcer during medication.And Chinese medicine exists
The advantage for treating thyroiditis seems especially prominent, therefore development efficacy is stable, cheap Chinese materia medica preparation is imperative.
[summary of the invention]
The object of the present invention is to provide a kind of compositions and preparation method thereof for treating thyroiditis, above-mentioned existing to solve
The defect of technology.
The invention adopts the following technical scheme:
The beneficial effects of the present invention are: preparation is convenient, and patient compliance is good, and what is had no toxic side effect is excellent with significant in efficacy
Gesture is worth clinical expansion and application.
[specific embodiment]
Below by embodiment, technical scheme of the present invention will be described in further detail.
The present invention provides a kind of compositions for treating thyroiditis, are made of the Chinese medicine material of following parts by weight:
One, function of each raw material in this drug and major function:
Fritillaria thunbergii: it is bitter, it trembles with fear.Return lung, the heart channel of Hang-Shaoyin.Heat-clearing dissipating bind, preventing phlegm from forming and stopping coughing, be used for wind-heat affecting lung, phlegm-fire cough, pulmonary abscess,
Acute mastitis, scrofula, sore.
Campanulaceae: it is bitter, pungent, it puts down.It is distributed in lung channel.Promoting the dispersing function of the lung, relieving sore-throat, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, chest distress, pharyngalgia,
Hoarse voice, lung carbuncle pyemesis, sore purulence is not at bursting.
Radix scrophulariae: it is sweet, bitter, salty, it is slightly cold.Return lung, stomach, kidney channel.Cool blood enriching yin, purging fire for removing toxin.For consumption of YIN caused by febrile disease, tongue is deep red tired
Yearningly, febrile virulent maculae, Tianjin hinder constipation, hectic fever due to yin labor is coughed, hot eyes, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Bombyx batryticatus: it is salty, pungent, it puts down.Return liver, lung, stomach meridian.Dispelling wind and relieving convulsion, reducing phlegm and resolving masses.For convulsion, abscess of throat, skin
Skin itch, submandibular lymph nodes is scorching, facioplegia.
Lasiosphaera fenzlii: it is pungent, it puts down.It is distributed in lung channel.Removing heat from the lung and relieving sorethroat, hemostasis.For the strongly fragrant lung pharyngalgia of wind-heat, cough, hoarse voice;Nosebleed epistaxis is controlled outside,
Wound hemorrhage.
Dandelion: taste sweet and neutral, it is nontoxic.It is clearing heat and detoxicating, diuresis dissipating bind.
Prunella vulgaris: it is pungent, bitter, it trembles with fear.Return liver, gallbladder channel.It relieves inflammation or internal heat, improving eyesight, dissipating bind, detumescence.For red eye, swell pain, eyeball night pain,
Headache and dizziness, scrofula, goiter, acute mastitis swelling and pain;Thyroid Gland Swell, scrofula, the proliferation of mammary gland, hypertension.
Honeysuckle flower: nature and flavor are sweet;It is cold.It is clearing heat and detoxicating, fry charcoal cooling blood and hemostasis.
Fructus Forsythiae: it is bitter, it is slightly cold.Return lung, the heart, small intestinl channel.It is clearing heat and detoxicating, dispersing swelling and dissipating binds.For ulcer, scrofula, acute mastitis is red
Poison, anemopyretic cold, warm disease is from the beginning of warm is joined the army, hyperpyrexia polydipsia, coma macular eruption, heat gonorrhea renal shutdown.
Radix paeoniae rubra: it is bitter, it is slightly cold.Return liver warp.Clearing heat and cooling blood, removing blood stasis and acesodyne.For febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain,
Liver-depressed hypochondrium pain, amenorrhea and algomenorrhea , abdominal mass and abdominal pain, injury from falling down, carbuncle swells sore.
Two, preparation method and usage and dosage
The preparation method of decoction of the present invention, specifically follows the steps below:
Step 1 weighs 16-20 parts of fritillaria thunbergii respectively by weight, and 6-9 parts of campanulaceae, 8-10 parts of radix scrophulariae, 8-10 parts of bombyx batryticatus,
8-10 parts of Lasiosphaera fenzlii, 4-6 parts of dandelion, 10-12 parts of Prunella vulgaris, 4-6 parts of honeysuckle flower, 6-9 parts of Fructus Forsythiae, 6-9 parts of radix paeoniae rubra, and by bulk pharmaceutical chemicals
It is placed in suitable container, the 4-10 times of water measured is added as solvent and submerges bulk pharmaceutical chemicals, is heated to boiling, holding is micro-, and to rise 1-3 small
When after filter out decocting liquid, decoct again, merge fried liquid;Above all medicines are to clean and shine dry-cure by removing impurity;
The fried liquid merged in step 1 is concentrated into 70-90 DEG C of relative density as 1.35 clear cream by step 2;It adds
Appropriate dextrin, granulation are crossed 14-16 mesh, are dried in vacuo at 70-90 DEG C, whole grain, dispense.
The usage and dosage of the traditional chinese medicine composition of the invention:
Every bag of granule is equivalent to 8 grams of crude drug, once a bag, once in the morning and once at night.
Embodiment 1
Step 1 weighs 20 parts of fritillaria thunbergii respectively by weight, and 9 parts of campanulaceae, 10 parts of radix scrophulariae, 10 parts of bombyx batryticatus, 10 parts of Lasiosphaera fenzlii,
6 parts of dandelion, 12 parts of Prunella vulgaris, 6 parts of honeysuckle flower, 9 parts of Fructus Forsythiae, 9 parts of radix paeoniae rubra.Bulk pharmaceutical chemicals are placed in suitable container, are added 4 times
The water of amount as solvent submerge bulk pharmaceutical chemicals, be heated to boiling, keep it is micro- rise 1 hour after filter out decocting liquid, decoct again, merge it is fried
Liquid;Above all medicines are to clean and shine dry-cure by removing impurity;
The fried liquid merged in step 1 is concentrated into 70 DEG C of relative density as 1.35 clear cream by step 2;It adds suitable
Dextrin is measured, granulation is crossed 14 meshes, is dried in vacuo at 70 DEG C, whole grain, dispenses.
Embodiment 2
Step 1 weighs 16 parts of fritillaria thunbergii respectively by weight, and 6 parts of campanulaceae, 8 parts of radix scrophulariae, 8 parts of bombyx batryticatus, 8 parts of Lasiosphaera fenzlii, Pu Gong
4 parts of English, 10 parts of Prunella vulgaris, 4 parts of honeysuckle flower, 6 parts of Fructus Forsythiae, 6 parts of radix paeoniae rubra.Bulk pharmaceutical chemicals are placed in suitable container, 10 times of amounts are added
Water as solvent submerge bulk pharmaceutical chemicals, be heated to boiling, keep it is micro- rise 3 hours after filter out decocting liquid, decoct again, merge it is fried
Liquid;Above all medicines are to clean and shine dry-cure by removing impurity;
The fried liquid merged in step 1 is concentrated into 90 DEG C of relative density as 1.35 clear cream by step 2;It adds suitable
Dextrin is measured, granulation is crossed 16 meshes, is dried in vacuo at 90 DEG C, whole grain, dispenses.
Embodiment 3
Step 1 weighs 18 parts of fritillaria thunbergii respectively by weight, and 7.5 parts of campanulaceae, 9 parts of radix scrophulariae, 9 parts of bombyx batryticatus, 9 parts of Lasiosphaera fenzlii, Pu
5 parts of public English, 11 parts of Prunella vulgaris, 5 parts of honeysuckle flower, 7.5 parts of Fructus Forsythiae, 7.5 parts of radix paeoniae rubra.Bulk pharmaceutical chemicals are placed in suitable container, are added 7
The water of times amount submerges bulk pharmaceutical chemicals as solvent, is heated to boiling, and filters out decocting liquid after keeping micro- and rising 2 hours, decocts, merge pan-fried again
Liquid out;Above all medicines are to clean and shine dry-cure by removing impurity;
The fried liquid merged in step 1 is concentrated into 80 DEG C of relative density as 1.35 clear cream by step 2;It adds suitable
Dextrin is measured, granulation is crossed 15 meshes, is dried in vacuo at 80 DEG C, whole grain, dispenses.
Three, Clinic Case
1, case-data: selection hospital outpatient thyroiditis patient 80 is divided into treatment group and right using parallel control method
According to group, every group 40.
Treatment group male 13, female 27, the age 18~50 years old, 34.56 ± 6.32 years old, course of disease 3-50d average, average course of disease
18.25±5.53d。
Control group male 12, women 28;It is age 20 years old~50 years old, 35.55 ± 6.43 years old, course of disease 1-55d average, it puts down
18.60 ± 6.33d of the equal course of disease.
Through statistical analysis, two groups of patient ages, gender, courses of disease etc. have comparable without significant difference (P > 0.05)
Property.
2, case diagnosis standard
It is before the onset of 1. to have infection of the upper respiratory tract history or parotitis medical history more;2. thyroid gland pain enlargement, obvious with tenderness, can
There is radiating pain, part can swell in diffusivity without redness or nodositas is swollen;3. have pharyngalgia, headache, fever, chilly, it is out of strength,
Hidrosis, or have neck constriction, hoarseness;4. free triiodothyronine (FT3), free thyroxine (FT4) rise
Height, thyroid-stimulating hormone (TSH) reduce;5. erythrocyte sedimentation rate (ESR) (ESR) is obviously speeded;6. thyroid gland Color Doppler ultrasound shows first
Two leaf anthorisma of shape gland, interior echo are unevenly distributed, and the low echo of sheet, color doppler flow imaging (CDFI) shows low time
Sound area blood flow signal reduces or nothing, and perilesional can visit and more rich blood flow signal.
Wind-heat phlegm resistance card CM syndrome differentiation criterion.Primary symptom: fever, chilly, headache, pharyngalgia, throat enlargement, pain, tenderness can have pressure
Compel sense or radiating pain;Minor symptom: hoarseness, red tongue body, thin white fur of tongue or thin Huang, superficial and rapid pulse or sliding number.
3, treatment method
Treatment group: bagged granules prepared by oral pharmaceutical composition embodiment 1 of the present invention, once a bag, once in the morning and once at night.
4 weeks are 1 course for the treatment of, continuously treat 2 courses for the treatment of.
Control group: prednisone, each 30mg take orally one time a day.It is reduced after body temperature, ESR are normal, subtract 5 weekly~
10mg, until being kept to daily 5mg and being gradually discontinued.One week for a course for the treatment of, the course for the treatment of are no more than 9 weeks.
4, the standard of curative effect evaluation
Recovery from illness: thyroid gland restores normal, and symptomatology, sign disappear, and serum FT 3, FT4, TSH and ESR are normal, and CDFI is just
Often;
Improve: thyroid gland pain disappears, and goitre mitigates I degree or more, and serum FT 3, FT4, TSH, ESR improvement >=
30%;
Invalid: symptom, sign and serum FT 3, FT4, TSH, ESR are not improved after treatment, or improve < before relatively treating
30%.
5, therapeutic effect:
During clinical observation, 80 patients complete clinical observation.Two groups of clinical effectiveness compare, and treatment group's clinic is fullyed recover from an illness
More rate 95%, clinical effectiveness is significant;Control group clinical recovery rate 70%.Two groups for the treatment of results compare, in terms for the treatment of group's cure rate
Treatment group's clinical effectiveness is more significant.Two groups of body temperature, thyroid gland pain improve the time and total treatment time compares, each side, treatment group
In terms of face effect is more significant, and thyroid gland pain improves time and total treatment time and control group has significant difference (P <
0.05).Recovery from illness case follow-up 3 months, treatment group is without recurrence;Control group recurs 10.
Claims (5)
1. the composition for treating thyroiditis, which is characterized in that be made of the Chinese medicine material of following parts by weight: fritillaria thunbergii 16-20
Part, 6-9 parts of campanulaceae, 8-10 parts of radix scrophulariae, 8-10 parts of bombyx batryticatus, 8-10 parts of Lasiosphaera fenzlii, 4-6 parts of dandelion, 10-12 parts of Prunella vulgaris, honeysuckle flower
4-6 parts, 6-9 parts of Fructus Forsythiae, 6-9 parts of radix paeoniae rubra.
2. the composition for the treatment of thyroiditis as described in claim 1, which is characterized in that by the Chinese medicine material of following parts by weight
Medicine is made: 20 parts of fritillaria thunbergii, 9 parts of campanulaceae, and 10 parts of radix scrophulariae, 10 parts of bombyx batryticatus, 10 parts of Lasiosphaera fenzlii, 6 parts of dandelion, 12 parts of Prunella vulgaris, silver
Spend 6 parts, 9 parts of Fructus Forsythiae, 9 parts of radix paeoniae rubra.
3. the composition for the treatment of thyroiditis as described in claim 1, which is characterized in that by the Chinese medicine material of following parts by weight
It is made: 16 parts of fritillaria thunbergii, 6 parts of campanulaceae, 8 parts of radix scrophulariae, 8 parts of bombyx batryticatus, 8 parts of Lasiosphaera fenzlii, 4 parts of dandelion, 10 parts of Prunella vulgaris, 4 parts of honeysuckle flower,
6 parts of Fructus Forsythiae, 6 parts of radix paeoniae rubra.
4. the composition for the treatment of thyroiditis as described in claim 1, which is characterized in that by the Chinese medicine material of following parts by weight
It is made: 18 parts of fritillaria thunbergii, 7.5 parts of campanulaceae, 9 parts of radix scrophulariae, 9 parts of bombyx batryticatus, 9 parts of Lasiosphaera fenzlii, 5 parts of dandelion, 11 parts of Prunella vulgaris, honeysuckle flower 5
Part, 7.5 parts of Fructus Forsythiae, 7.5 parts of radix paeoniae rubra.
5. the preparation method of the composition for the treatment of thyroiditis described in a kind of any one of claim 1-4, feature exist
In specifically following the steps below:
Step 1 weighs 16-20 parts of fritillaria thunbergii respectively by weight, and 6-9 parts of campanulaceae, 8-10 parts of radix scrophulariae, 8-10 parts of bombyx batryticatus, Lasiosphaera fenzlii
8-10 parts, 4-6 parts of dandelion, 10-12 parts of Prunella vulgaris, 4-6 parts of honeysuckle flower, 6-9 parts of Fructus Forsythiae, 6-9 parts of radix paeoniae rubra, and bulk pharmaceutical chemicals are placed in
In suitable container, the 4-10 times of water measured is added as solvent and submerges bulk pharmaceutical chemicals, is heated to boiling, holding is micro- rise 1-3 hours after
Decocting liquid is filtered out, is decocted again, fried liquid is merged;Above all medicines are to clean and shine dry-cure by removing impurity;
The fried liquid merged in step 1 is concentrated into 70-90 DEG C of relative density as 1.35 clear cream by step 2;It adds appropriate
Dextrin, granulation are crossed 14-16 mesh, are dried in vacuo at 70-90 DEG C, whole grain, dispense.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711199963.9A CN109833417A (en) | 2017-11-27 | 2017-11-27 | The composition and preparation method thereof for treating thyroiditis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711199963.9A CN109833417A (en) | 2017-11-27 | 2017-11-27 | The composition and preparation method thereof for treating thyroiditis |
Publications (1)
Publication Number | Publication Date |
---|---|
CN109833417A true CN109833417A (en) | 2019-06-04 |
Family
ID=66879555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201711199963.9A Withdrawn CN109833417A (en) | 2017-11-27 | 2017-11-27 | The composition and preparation method thereof for treating thyroiditis |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109833417A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112807362A (en) * | 2021-03-16 | 2021-05-18 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating subacute thyroiditis in acute stage and preparation method and application thereof |
CN113786436A (en) * | 2021-10-09 | 2021-12-14 | 江苏省中医院 | Traditional Chinese medicine composition, preparation thereof and application of traditional Chinese medicine composition in treatment of subacute thyroiditis |
CN115089682A (en) * | 2022-08-09 | 2022-09-23 | 林燕 | A Chinese medicinal composition for treating thyroid diseases, and its preparation method |
-
2017
- 2017-11-27 CN CN201711199963.9A patent/CN109833417A/en not_active Withdrawn
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112807362A (en) * | 2021-03-16 | 2021-05-18 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating subacute thyroiditis in acute stage and preparation method and application thereof |
CN112807362B (en) * | 2021-03-16 | 2022-02-22 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating subacute thyroiditis in acute stage and preparation method and application thereof |
CN113786436A (en) * | 2021-10-09 | 2021-12-14 | 江苏省中医院 | Traditional Chinese medicine composition, preparation thereof and application of traditional Chinese medicine composition in treatment of subacute thyroiditis |
CN115089682A (en) * | 2022-08-09 | 2022-09-23 | 林燕 | A Chinese medicinal composition for treating thyroid diseases, and its preparation method |
CN115089682B (en) * | 2022-08-09 | 2023-05-05 | 林燕 | Traditional Chinese medicine composition for treating thyroid diseases and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101884770B (en) | Chinese medicinal preparation for treating urolithiasis and preparation method thereof | |
CN103041317B (en) | A kind of Chinese medicine composition for the treatment of tumor and preparation method thereof | |
CN101961415B (en) | Decoction for treating chronic urticaria | |
CN109833417A (en) | The composition and preparation method thereof for treating thyroiditis | |
CN104784642B (en) | A kind of pharmaceutical composition treating subacute thyroiditis | |
CN103041341B (en) | Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof | |
CN113713039A (en) | Traditional Chinese medicine composition for treating membranous nephropathy and application thereof | |
CN103203006B (en) | Traditional Chinese medicine decoction for treating uterus coldness | |
CN102886036B (en) | Traditional Chinese medicine for treating syndrome of congealing cold with blood stasis type dysmenorrheal disease | |
CN102293969B (en) | Chinese medicine for treating fatty liver | |
CN107596072A (en) | It is a kind of effectively to treat ointment medicine of whelk and preparation method thereof | |
CN102716266A (en) | Buffalo horn-unprocessed rehmannia-lithospermum-cortex dictamni medicinal decoction for treating anaphylactoid purpura | |
CN102552767B (en) | Traditional Chinese medicine for treating kidney stone, preparation method and administration mode | |
CN101829248A (en) | Traditional Chinese medicine for treating goiter | |
CN104306948A (en) | Medicament composition for treating gouty arthritis | |
CN105125814B (en) | It is a kind of to treat chronic renal failure III, the Chinese medicine composition of IV phase | |
CN102228661B (en) | Chinese medicinal cholecystitis treatment mixture for treating chronic cholecystitis | |
CN105031516A (en) | Chinese herbal unguent for curing erysipelas | |
CN104274708A (en) | Traditional Chinese medicine for treating hyperthyroidism | |
CN104435152A (en) | Traditional Chinese medicine agent with functions of tranquilizing and allaying excitement for treating stage I of hypertension and preparation method | |
CN104306457A (en) | Injection liquid for treating epidemic cerebrospinal meningitis and preparation method thereof | |
CN103690901A (en) | Traditional Chinese medicine for treating cholelithiasis and preparation method thereof | |
CN102274437B (en) | Blood poison eliminating capsules | |
CN113288969A (en) | Medicine for treating bronchitis and preparation method thereof | |
CN108143779A (en) | A kind of Chinese medicine composition for treating cardiovascular and cerebrovascular disease |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20190604 |
|
WW01 | Invention patent application withdrawn after publication |