CN104784642B - A kind of pharmaceutical composition treating subacute thyroiditis - Google Patents
A kind of pharmaceutical composition treating subacute thyroiditis Download PDFInfo
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Abstract
The invention belongs to pharmaceutical technology field, be specifically related to a kind of pharmaceutical composition treating subacute thyroiditis.Described pharmaceutical composition is made up of Bulbus Fritillariae Thunbergii, Radix Platycodonis, Radix Scrophulariae, Bombyx Batryticatus, Lasiosphaera Seu Calvatia, Rhizoma Curcumae, Spica Prunellae, Flos Gardeniae, Fructus Forsythiae, Radix Paeoniae Rubra.Pharmaceutical composition of the present invention has effect of relieving sore-throat by clearing away heat, dissipating phlegm and resolving masses, cooling blood and relieving pain, through clinical trial certificate, use medicine composite for curing subacute thyroiditis of the present invention preparation simple, determined curative effect, have no side effect, be a kind of active drug treating subacute thyroiditis.
Description
Technical field
The invention belongs to pharmaceutical technology field, be specifically related to a kind of pharmaceutical composition treating subacute thyroiditis.
Background technology
Subacute thyroiditis is the thyroid disease that a kind of sickness rate is higher, and age of onset 20-60 year is in the majority, and female middle-aged is sent out
Sick rate is high, and the allergy caused after infecting with virus is relevant, with heating, thyroid tract pain, thyromegaly, companion
There are hyperthyroidism, hypothyroidism etc. for main clinical characteristics.
The traditional Chinese medical science thinks that primary disease belongs to " goiter " category.Ancient Times in China doctor thinks that the main pathogenesis of goiter is that expectorant is solidifying, the stagnation of QI, blood
Tired heap soil or fertilizer over and around the roots is tied in throat.Wherein some patients is due to mental disorder pent-up fire-transformation, fire consumption impairment of YIN essence, thus causes the pathology of hyperactivity of fire caused by deficiency of YIN to become
Change.Goiter initial stage many excess syndromes, day prolonged illness can be changed into deficiency syndrome by excess syndrome, especially based on the deficiency of vital energy, the deficiency of YIN, thus occurs in that deficiency and excess
The complicated disease being mingled with.In conjunction with modern Chinese medicine theory of development, from improving curative effect of medication, the angle of reduction side effect,
Through Chinese medicine being carried out the Chinese medicine preparation that screening is extracted and/or compatibility prepares, treatment primary disease shows unique advantage, not only
Clinical symptoms can be made to obtain rapid recovery, and make relapse rate be substantially reduced, improve the quality of life of patient, be worth more
Add deep carrying out to research and develop.
Summary of the invention
The present invention is by plus-minus taste on the basis of existing prescription, it is provided that a kind of ideal being suitable to treat subacute thyroiditis
External treatment dosage form.It is rigorous that the present invention has prescription, compatibility science, evident in efficacy, and preparation is convenient, and patient compliance is good, nontoxic
The advantage of side effect, clinic promotion and application.
For reaching above-mentioned purpose, the technical scheme that the present invention provides is the pharmaceutical composition of described treatment subacute thyroiditis,
It is characterized in that described pharmaceutical composition is made up of the medicine of following weight portion: Bulbus Fritillariae Thunbergii 16-20 part, Radix Platycodonis 6-9 part, Radix Scrophulariae
8-10 part, Bombyx Batryticatus 8-10 part, Lasiosphaera Seu Calvatia 8-10 part, Rhizoma Curcumae 4-6 part, Spica Prunellae 10-12 part, Flos Gardeniae 4-6 part, Fructus Forsythiae
6-9 part, Radix Paeoniae Rubra 6-9 part.
Most preferred technique scheme of the present invention is that pharmaceutical composition of the present invention is prepared by the material medicine of following weight portion:
Bulbus Fritillariae Thunbergii 18 parts, Radix Platycodonis 7 parts, Radix Scrophulariae 9 parts, Bombyx Batryticatus 9 parts, Lasiosphaera Seu Calvatia 9 parts, Rhizoma Curcumae 5 parts, Spica Prunellae 11 parts, Cape jasmine
Son spends 5 parts, Fructus Forsythiae 8 parts, Radix Paeoniae Rubra 7 parts.
The preparation method of described pharmaceutical composition has the following steps: weigh above Chinese medicine component powder respectively according to aforesaid weight portion
It is broken into coarse powder, mix homogeneously, adds the water of medical material gross weight 8 times amount, decoct 5h, filter；It is clear paste that filtrate concentrates, and is dried,
Be ground into fine powder, add proper auxiliary materials, eventually pass normal process steps add pharmaceutically acceptable excipients make clinic can
The dosage form accepted.
Pharmaceutical composition of the present invention is preferably prepared to external preparation.It is prepared as ointment, gel, lotion specifically
Or transdermal patch etc..
When above-mentioned external preparation is ointment, the prescription of described ointment is as follows:
The preparation method of described ointment has the following steps: the sodium lauryl sulphate taking recipe quantity is dissolved in suitable quantity of water, adds
Enter glycerol and put the aqueous phase being heated to 75 DEG C in water-bath；Separately take white vaseline, hexadecanol, glyceryl monostearate, Metagin
Ester mix homogeneously, in water-bath, heating makes fusing, the oil phase keeping temperature to be 75 DEG C；Oil phase is slowly added in aqueous phase, with
Add with stirring, when letting cool, traditional Chinese medicine fine powder is slowly added in emulsifiable paste matrix, stirring, to obtain final product.
The present invention, relative to prior art, has a following clear superiority:
First, pharmaceutical composition prescription of the present invention mainly develops according to the pathogenic characteristic of subacute thyroiditis patient,
Bulbus Fritillariae Thunbergii, Fructus Forsythiae, Bombyx Batryticatus heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, preventing phlegm from forming and stopping coughing in side；Radix Platycodonis, Lasiosphaera Seu Calvatia removing heat from the lung and relieving sorethroat, the row of eliminating the phlegm
Pus；Radix Scrophulariae, Radix Paeoniae Rubra, Spica Prunellae, Flos Gardeniae clearing away heat and cooling blood, mass dissipating and swelling eliminating, eliminating fire and detoxication；Rhizoma Curcumae promoting the circulation of QI to relieve pain.All medicines
Share the merit with relieving sore-throat by clearing away heat, dissipating phlegm and resolving masses, cooling blood and relieving pain, subacute thyroiditis is had extremely strong specific aim curative effect.
Verify by clinic application, its determined curative effect, mild in medicine property and, toxic and side effects and untoward reaction do not occur, safety coefficient is high.
Further, in pharmaceutical composition of the present invention, the function of each crude drug cures mainly:
Bulbus Fritillariae Thunbergii, bitter, cold.Return lung, heart channel.Heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing, for wind-heat invading the lung, phlegm-fire cough, lung
Carbuncle, acute mastitis, scrofula, sore.
Radix Platycodonis, bitter, pungent, flat.Return lung meridian.Lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.It is not for cough with copious phlegm, uncomfortable in chest smooth,
Pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Radix Scrophulariae, sweet, bitter, salty, it is slightly cold.Return lung, stomach, kidney channel.Removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease,
Crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus are hindered in Tianjin.
Bombyx Batryticatus, salty, pungent, flat.Return liver, lung, stomach warp.Expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, swelling throat
Bitterly, skin pruritus, submandibular lymph nodes is scorching, facial paralysis.
Lasiosphaera Seu Calvatia, pungent, flat.Return lung meridian.Removing heat from the lung and relieving sorethroat, hemostasis.For wind heat strongly fragrant lung pharyngalgia, cough, hoarseness；External treatment nose
Nosebleed, wound hemorrhage.
Rhizoma Curcumae, pungent, bitter, temperature.Return liver, spleen channel.Circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For abdominal mass mass in the abdomen, blood stasis amenorrhea,
Food stagnation distending pain；Early cervical carcinoma.
Spica Prunellae, pungent, bitter, cold.Return liver, gallbladder meridian.Relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, mesh pearl
Nyctalgia, dizziness of having a headache, scrofula, goiter, acute mastitis swells and ache；Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Flos Gardeniae, cold；Bitter.Lung；Liver Channel.Clearing away lung-heat to relieve cough；Cooling blood for hemostasis.Main cough due to lung-heat；Epistaxis.(prescription is write on earth
Flos Gardeniae or Fructus Gardeniae)
Fructus Forsythiae, bitter, it is slightly cold.Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis,
Erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warm is joined the army, high hot excessive thirst, and coma sends out speckle, pyretic stranguria urine retention.
Radix Paeoniae Rubra, bitter, it is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion swells
Bitterly, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, abdominal mass stomachache, injury from falling down, carbuncle skin infection.
The present invention is also claimed aforementioned pharmaceutical compositions purposes in the medicine of preparation treatment subacute thyroiditis.Facing
During bed is observed, 80 example subacute thyroiditis patients being randomly divided into treatment group and matched group is treated, treatment group makes
Showing with after 2 courses for the treatment of of Drug therapy of the present invention, symptom can significantly improve.And treatment group is in whole therapeutic process
Do not find the obvious adverse events such as allergy.Result shows that the clinical application of we is safely and effectively, is worth research further
And popularization and application.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, but the present invention is not limited only to specific examples below.?
In the scope of the present invention or without departing from present disclosure, spirit and scope, change that the present invention is carried out, combination
Or replace, will be apparent to the person skilled in the art, and be included within the scope of the present invention.
Embodiment 1 ointment
The each raw material of the present invention is weighed: Bulbus Fritillariae Thunbergii 18 parts, Radix Platycodonis 7 parts, Radix Scrophulariae 9 parts, Bombyx Batryticatus 9 parts, horse by following weight portion
Vigorous 9 parts, Rhizoma Curcumae 5 parts, Spica Prunellae 11 parts, Flos Gardeniae 5 parts, Fructus Forsythiae 8 parts, Radix Paeoniae Rubra 7 parts.
Preparation technology is as follows:
The preparation method of described pharmaceutical composition has the following steps: weigh above Chinese medicine component powder respectively according to aforesaid weight portion
It is broken into coarse powder, mix homogeneously, adds the water of medical material gross weight 8 times amount, decoct 5h, filter；It is clear paste that filtrate concentrates, and is dried,
It is ground into fine powder, standby.
Take sodium lauryl sulphate 8 parts to be dissolved in suitable quantity of water, add glycerol 40 parts and put the aqueous phase being heated to 75 DEG C in water-bath；
Separately take white vaseline 30 parts, hexadecanol 70 parts, glyceryl monostearate 15 parts, 1 part of mix homogeneously of methyl hydroxybenzoate,
In water-bath, heating makes fusing, the oil phase keeping temperature to be 75 DEG C；Oil phase is slowly added in aqueous phase, with adding with stirring, lets cool
Time, traditional Chinese medicine fine powder 70 parts is slowly added in emulsifiable paste matrix, stirring, obtains 1000 parts of ointments.
When using medicine composite for curing subacute thyroiditis of the present invention, using prepared ointment, every day 2-3 time is uniformly
Coating affected part.
Embodiment 2 ointment
The each raw material of the present invention is weighed: Bulbus Fritillariae Thunbergii 18 parts by following weight proportion, Radix Platycodonis 7 parts, Radix Scrophulariae 9 parts, Bombyx Batryticatus 9 parts,
Lasiosphaera Seu Calvatia 9 parts, Rhizoma Curcumae 5 parts, Spica Prunellae 11 parts, Flos Gardeniae 5 parts, Fructus Forsythiae 8 parts, Radix Paeoniae Rubra 7 parts.
Preparation technology is as follows:
The preparation method of described pharmaceutical composition has the following steps: weigh above Chinese medicine component powder respectively according to aforesaid weight portion
It is broken into coarse powder, mix homogeneously, adds the water of medical material gross weight 8 times amount, decoct 5h, filter；It is clear paste that filtrate concentrates, and is dried,
It is ground into fine powder, standby.
Take sodium lauryl sulphate 5 parts to be dissolved in suitable quantity of water, add glycerol 30 parts and put the aqueous phase being heated to 75 DEG C in water-bath；
Separately take white vaseline 20 parts, hexadecanol 80 parts, glyceryl monostearate 10 parts, 0.5 part of mix homogeneously of methyl hydroxybenzoate,
In water-bath, heating makes fusing, the oil phase keeping temperature to be 75 DEG C；Oil phase is slowly added in aqueous phase, with adding with stirring, puts
Time cold, traditional Chinese medicine fine powder 50 parts is slowly added in emulsifiable paste matrix, stirring, obtains 1000 parts of ointments.
When using medicine composite for curing subacute thyroiditis of the present invention, using prepared ointment, every day 2-3 time is uniformly
Coating affected part.
Embodiment 3 ointment
The each raw material of the present invention is weighed: Bulbus Fritillariae Thunbergii 18 parts by following weight proportion, Radix Platycodonis 7 parts, Radix Scrophulariae 9 parts, Bombyx Batryticatus 9 parts,
Lasiosphaera Seu Calvatia 9 parts, Rhizoma Curcumae 5 parts, Spica Prunellae 11 parts, Flos Gardeniae 5 parts, Fructus Forsythiae 8 parts, Radix Paeoniae Rubra 7 parts.
Preparation technology is as follows:
The preparation method of described pharmaceutical composition has the following steps: weigh above Chinese medicine component powder respectively according to aforesaid weight portion
It is broken into coarse powder, mix homogeneously, adds the water of medical material gross weight 8 times amount, decoct 5h, filter；It is clear paste that filtrate concentrates, and is dried,
It is ground into fine powder, standby.
Take sodium lauryl sulphate 10 parts to be dissolved in suitable quantity of water, add glycerol 50 parts and put the aqueous phase being heated to 75 DEG C in water-bath；
Separately take white vaseline 40 parts, hexadecanol 80 parts, glyceryl monostearate 20 parts, 1.5 parts of mix homogeneously of methyl hydroxybenzoate,
In water-bath, heating makes fusing, the oil phase keeping temperature to be 75 DEG C；Oil phase is slowly added in aqueous phase, with adding with stirring, puts
Time cold, traditional Chinese medicine fine powder 80 parts is slowly added in emulsifiable paste matrix, stirring, obtains 1000 parts of ointments.
When using medicine composite for curing subacute thyroiditis of the present invention, using prepared ointment, every day 2-3 time is uniformly
Coating affected part.
Embodiment 4
The each raw material of the present invention is weighed: Bulbus Fritillariae Thunbergii 16 parts by following weight proportion, Radix Platycodonis 6 parts, Radix Scrophulariae 8 parts, Bombyx Batryticatus 8 parts,
Lasiosphaera Seu Calvatia 8 parts, Rhizoma Curcumae 4 parts, Spica Prunellae 10 parts, Flos Gardeniae 4 parts, Fructus Forsythiae 6 parts, Radix Paeoniae Rubra 6 parts.
Preparation technology is with embodiment 1.
Embodiment 5
The each raw material of the present invention is weighed: Bulbus Fritillariae Thunbergii 20 parts by following weight proportion, Radix Platycodonis 9 parts, Radix Scrophulariae 10 parts, Bombyx Batryticatus 10 parts,
Lasiosphaera Seu Calvatia 10 parts, Rhizoma Curcumae 6 parts, Spica Prunellae 12 parts, Flos Gardeniae 6 parts, Fructus Forsythiae 9 parts, Radix Paeoniae Rubra 9 parts.
Preparation technology is with embodiment 1.
The clinical observation of embodiment 6 medicine composite for curing of the present invention subacute thyroiditis
1, case-data: select hospital outpatient wind heat stagnation of phlegm card subacute thyroiditis patient 80 example, use parallel control method
It is divided into treatment group and matched group, often organizes 40 examples.Male 13 examples for the treatment of group, female 27 example, age 18～50 years old, average 34.56
± 6.32 years old, course of disease 3-50d, average course of disease 18.25 ± 5.53d.Matched group male 12 example, women 28 example；Age 20
Year～50 years old, average 35.55 ± 6.43 years old, course of disease 1-55d, average course of disease 18.60 ± 6.33d.Through statistical analysis, two groups
The aspects such as patient age, sex, the course of disease, without significant difference (P ＞ 0.05), have comparability.
2, case diagnosis standard
1. premorbid has upper respiratory tract infection history or parotitis medical history more；2. thyroid pain enlargement, companion touches a tender spot substantially, can have
Radiating pain, without red and swollen, can swell in diffusivity or nodositas swells in local；3. have pharyngalgia, have a headache, generate heat, fear of cold, weary
Power, hyperhidrosis, or have cervical region constriction, hoarseness；4. free triiodothyronine (FT3), free thyroxine (FT4)
Raising, thyrotropin (TSH) reduces；5. erythrocyte sedimentation rate (ESR) substantially speeds；6. thyroid color doppler ultrasonography
Show thyroid two leaf anthorisma, interior echo skewness, the low echo of lamellar, color doppler flow imaging (CDFI)
Showing that low echo area blood flow signal reduces or nothing, perilesional can be visited and more rich blood flow signal.
Wind heat stagnation of phlegm card CM syndrome differentiation criterion.Primary symptom: heating, fear of cold, headache, pharyngalgia, throat enlargement, pain, tenderness, can
There are constriction or radiating pain；Secondary disease: hoarseness, red tongue, thin white fur of tongue or BOHUANG, floating and rapid pulse or sliding number.
3, Therapeutic Method
Treatment group: use the ointment thickness uniform application cervical region with 0.1-0.2cm of pharmaceutical composition embodiment 1 of the present invention preparation,
Three times a day.Within 4 weeks, it is 1 course for the treatment of, 2 courses for the treatment of of treatment continuously.
Matched group: prednisone, each 30mg, every day 1 time, oral.Decrement after body temperature, ESR are normal, weekly
Subtract 5～10mg, until being kept to 5mg every day and gradually drug withdrawal.Within 1 week, being 1 course for the treatment of, the course for the treatment of is less than 9 weeks.
4, the standard of curative effect evaluation
Recovery from illness: thyroid recovers normal, and symptomatology, sign disappear, serum FT 3, FT4, TSH and ESR are normal,
CDFI is normal；
Take a turn for the better: thyroid pain disappear, goiter alleviates more than I degree, serum FT 3, FT4, TSH, ESR improve >=
30%；
Invalid: after treatment, symptom, sign and serum FT 3, FT4, TSH, ESR are not improved, or improve before relatively treatment
＜ 30%.
5, therapeutic effect:
During clinical observation, 80 example patients all complete clinical observation.Two groups of clinical effectiveness compare, treatment group clinical recovery
Rate 95%, clinical effectiveness is notable；Matched group clinical recovery rate 70%.Two groups of therapeutic outcomes compare, treatment group cure rate aspect
Treatment group clinical effectiveness is the most notable.Concrete outcome is shown in Table 1.Two groups of body temperature, thyroid pain improve time and total treatment time
Relatively it is shown in Table 2.Two groups of body temperature, thyroid pain improve the time and total treatment time compares, and treatment group each side effect is the most aobvious
Write, and thyroid pain is improved time and total treatment time aspect and had significant difference (P ＜ 0.05) with matched group.Recovery from illness
Case is followed up a case by regular visits to 3 months, and treatment group is without recurrence；Matched group recurs 10 examples.
1. liang of table group clinical effectiveness compares
| Group | Recovery from illness | Take a turn for the better | Invalid |
| Treatment group | 38 | 2 | 0 |
| Matched group | 28 | 12 | 0 |
Table 2. body temperature, thyroid pain improve time and total treatment time (d)
The above results shows, after the medicine composite for curing of subacute thyroiditis disease patient's the application of the invention, symptom is permissible
Significantly improve.It addition, treatment group does not finds the obvious adverse events such as allergy in whole therapeutic process.Result shows
The clinical application of we is safely and effectively, is worth research popularization and application further.
Claims (8)
1. the pharmaceutical composition treating subacute thyroiditis, it is characterised in that the composition and ratio of its crude drug is:
Bulbus Fritillariae Thunbergii 16-20 part, Radix Platycodonis 6-9 part, Radix Scrophulariae 8-10 part, Bombyx Batryticatus 8-10 part, Lasiosphaera Seu Calvatia 8-10 part, Rhizoma Curcumae 4-6 part,
Spica Prunellae 10-12 part, Flos Gardeniae 4-6 part, Fructus Forsythiae 6-9 part, Radix Paeoniae Rubra 6-9 part；Described pharmaceutical composition is external preparation.
A kind of pharmaceutical composition treating subacute thyroiditis, it is characterised in that its crude drug
Composition and ratio be: Bulbus Fritillariae Thunbergii 18 parts, Radix Platycodonis 7 parts, Radix Scrophulariae 9 parts, Bombyx Batryticatus 9 parts, Lasiosphaera Seu Calvatia 9 parts, Rhizoma Curcumae 5 parts, summer
Hay 11 parts, Flos Gardeniae 5 parts, Fructus Forsythiae 8 parts, Radix Paeoniae Rubra 7 parts.
A kind of pharmaceutical composition treating subacute thyroiditis, it is characterised in that described
The preparation method of pharmaceutical composition has the following steps: weighs above Chinese medicinal components according to aforesaid weight portion and is respectively crushed into coarse powder,
Mix homogeneously, adds the water of medical material gross weight 8 times amount, decocts 5h, filters；It is clear paste that filtrate concentrates, and dry, pulverize into thin
Powder, adds proper auxiliary materials, eventually pass normal process steps add pharmaceutically acceptable excipients make clinically-acceptable outside
Use dosage form.
A kind of pharmaceutical composition treating subacute thyroiditis, it is characterised in that described external
Preparation is ointment or gel.
A kind of pharmaceutical composition treating subacute thyroiditis, it is characterised in that described emulsifiable paste
The prescription of agent is as follows, in parts by weight:
A kind of pharmaceutical composition treating subacute thyroiditis, it is characterised in that described emulsifiable paste
The preparation method of agent has the following steps: the sodium lauryl sulphate taking recipe quantity is dissolved in suitable quantity of water, adds glycerol and puts water-bath
On be heated to the aqueous phase of 75 DEG C；Separately take white vaseline, hexadecanol, glyceryl monostearate, methyl hydroxybenzoate mix homogeneously,
In water-bath, heating makes fusing, the oil phase keeping temperature to be 75 DEG C；Oil phase is slowly added in aqueous phase, with adding with stirring, puts
Time cold, traditional Chinese medicine fine powder is slowly added in emulsifiable paste matrix, stirring, to obtain final product.
7. the pharmaceutical composition as claimed in claim 1 or 2 use in the pharmaceutical composition of preparation treatment subacute thyroiditis
On the way.
8. pharmaceutical composition as claimed in claim 1 or 2 is in the medicine group of preparation treatment wind heat phlegm retention subacute thyroiditis
Purposes in compound.
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| CN105477356A (en) * | 2015-10-31 | 2016-04-13 | 菏泽海诺知识产权服务有限公司 | Traditional Chinese medicine for treating subacute thyroiditis |
| CN105943969A (en) * | 2016-05-24 | 2016-09-21 | 董伟 | Traditional Chinese medicinal composition for treating subacute thyroiditis |
| CN110624081A (en) * | 2019-11-05 | 2019-12-31 | 辽宁中医药大学附属医院 | Traditional Chinese medicine composition for treating goiter and preparation method thereof |
| CN113599481B (en) * | 2021-09-24 | 2022-08-30 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating thyroid diseases and preparation method and application thereof |
| CN113786436B (en) * | 2021-10-09 | 2022-09-06 | 江苏省中医院 | Traditional Chinese medicine composition, preparation thereof and application of traditional Chinese medicine composition in treatment of subacute thyroiditis |
Citations (3)
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|---|---|---|---|---|
| CN101152535A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating subacute thyroiditis |
| CN103751718A (en) * | 2014-01-14 | 2014-04-30 | 江苏省中医药研究院 | Traditional Chinese medicine composition containing red peony root |
| CN104127747A (en) * | 2014-08-09 | 2014-11-05 | 杨其义 | Traditional Chinese medicament for treating suppurative tonsillitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152535A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating subacute thyroiditis |
| CN103751718A (en) * | 2014-01-14 | 2014-04-30 | 江苏省中医药研究院 | Traditional Chinese medicine composition containing red peony root |
| CN104127747A (en) * | 2014-08-09 | 2014-11-05 | 杨其义 | Traditional Chinese medicament for treating suppurative tonsillitis |
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