CN115089682B - Traditional Chinese medicine composition for treating thyroid diseases and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating thyroid diseases and preparation method thereof Download PDFInfo
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- CN115089682B CN115089682B CN202210952326.9A CN202210952326A CN115089682B CN 115089682 B CN115089682 B CN 115089682B CN 202210952326 A CN202210952326 A CN 202210952326A CN 115089682 B CN115089682 B CN 115089682B
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for treating thyroid diseases and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-20 parts of honeysuckle, 10-20 parts of weeping forsythia, 20-40 parts of fructus trichosanthis, 10-20 parts of radix ranunculi ternati, 10-20 parts of fritillaria thunbergii, 10-20 parts of selfheal, 10-20 parts of radix paeoniae rubra, 20-40 parts of radix salviae miltiorrhizae, 20-40 parts of radix scrophulariae, 10-20 parts of rhizoma curcumae, 10-20 parts of frankincense and 10-20 parts of myrrh. The traditional Chinese medicine composition provided by the invention has excellent treatment effect on thyroid diseases, has definite curative effect, is safe and reliable, can quickly relieve illness, and provides excellent service for patients through clinical practice verification. The traditional Chinese medicinal materials used in the traditional Chinese medicinal composition for treating thyroid diseases are all common nontoxic traditional Chinese medicines, are safe and reliable, have a simple preparation method, are pollution-free to the environment, and have great popularization and application values.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating thyroid diseases and a preparation method thereof.
Background
In recent years, clinical physical examination data show that the thyroid nodule detection rate of adults in China is higher, and the thyroid nodule detection rate becomes an environmental health problem which needs to be highly valued by the health administration department in China. Thyroid disorders are most commonly referred to as thyroid nodules, and any thyroid disorder can exist in the form of nodules, so thyroid nodules are involved in almost all thyroid disorders. Epidemiological studies have shown that in iodine-rich areas, 5% of women and 1% of men have reachable thyroid nodules; after high resolution ultrasound examination, 19% -67% of randomly selected populations had thyroid nodules. At present, the average prevalence of thyroid nodules of residents in China is 32.4%, and the average prevalence of thyroid nodules is a year-by-year growing trend.
At present, the incidence rate of thyroid diseases in China is high, the current situations of low awareness rate, low diagnosis rate and low treatment rate exist generally, and the overall treatment rate of the thyroid diseases is less than 5%. Thyroid nodule patients have no obvious clinical symptoms in early stages, and most patients are found on physical examination. Modern Western medicine has no special treatment means for benign thyroid nodule. If severe compression, malignant transformation tendency, tumor in special position and other conditions, can be treated by surgery, some other conservative treatment methods, but in domestic and foreign guidelines are not recommended to be used as conventional treatment means, which is also the main cause of low treatment rate of thyroid nodule diseases. Because there is no good treatment method and the early symptoms of the patient are not obvious, the treatment of the disease is ignored. It is therefore desirable to find a way to solve the above problems.
The traditional Chinese medicine has long history in preventing and treating thyroid nodule, can avoid adverse reactions such as hypothyroidism, local tissue damage, severe pain and the like caused by traumatic treatment such as surgery and the like, and is helpful for relieving psychological pressure of patients. The existing medicine for treating thyroid nodule contains very common Chinese medicinal materials such as herba Euphorbiae Humifusae, herba Senecionis Scandentis, radix Cicadae, herba Desmodii Styracifolii, and white snail shell, or toxic Chinese medicinal materials such as Mylabris and Catharsii Molossi. The used very common medicinal materials may have insufficient resources or have incomplete researches, and the like, are difficult to mass produce and have certain dangers; the use of toxic components increases the risk of adverse reactions, leading to allergic or toxic conditions.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide a traditional Chinese medicine composition for treating thyroid diseases and a preparation method thereof. The components of the medicinal materials adopted by the invention are common, safe and nontoxic traditional Chinese medicinal materials, and each component can exert the medicinal effect through accurate compatibility, so as to achieve the optimal treatment effect.
In order to achieve the above purpose, the embodiment of the invention provides a traditional Chinese medicine composition for treating thyroid diseases, which comprises the following raw materials in parts by weight: 10-20 parts of honeysuckle, 10-20 parts of weeping forsythia, 20-40 parts of fructus trichosanthis, 10-20 parts of radix ranunculi ternati, 10-20 parts of fritillaria thunbergii, 10-20 parts of selfheal, 10-20 parts of radix paeoniae rubra, 20-40 parts of radix salviae miltiorrhizae, 20-40 parts of radix scrophulariae, 10-20 parts of rhizoma curcumae, 10-20 parts of frankincense and 10-20 parts of myrrh.
Further, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 12-18 parts of honeysuckle, 12-18 parts of weeping forsythiae capsule, 24-36 parts of melon basket, 12-18 parts of radix ranunculi ternati, 12-18 parts of thunberg fritillary bulb, 12-18 parts of selfheal, 12-18 parts of red paeony root, 24-36 parts of red sage root, 24-36 parts of figwort root, 12-18 parts of curcuma zedoary, 12-18 parts of frankincense and 12-18 parts of myrrh.
Further, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 14-16 parts of honeysuckle, 14-16 parts of weeping forsythiae capsule, 28-32 parts of melon basket, 14-16 parts of radix ranunculi ternati, 14-16 parts of thunberg fritillary bulb, 14-16 parts of selfheal, 12-18 parts of red paeony root, 28-32 parts of red sage root, 28-32 parts of figwort root, 14-16 parts of rhizoma curcumae, 14-16 parts of frankincense and 14-16 parts of myrrh.
Further, the traditional Chinese medicine composition also comprises pharmaceutically acceptable auxiliary materials.
Further, the dosage forms of the traditional Chinese medicine composition comprise decoction, granules, pills, tablets, powder, paste and patches.
The embodiment of the invention provides a preparation method of a traditional Chinese medicine composition for treating thyroid diseases, wherein the traditional Chinese medicine composition is in the form of a patch, and the preparation method comprises the following steps:
weighing the raw materials according to the formula, pulverizing, sieving with 80-100 mesh sieve, adding white wine and vaseline, concocting into paste, and packaging into adhesive plaster.
Further, the addition amount of the white spirit is 15-25% of the total mass of the raw materials.
Further, the addition amount of the vaseline is 15-25% of the total mass of the raw materials.
Thyroid diseases mentioned in the present invention include various benign thyroid nodules and thyroiditis. For thyromegaly caused by light and moderate benign thyroid nodule and thyroiditis, including people with confirmed physical examination of thyroid nodule, asymptomatic or unobvious symptoms, or people who refuse oral medication or are hesitant to treatment, the external preparation provided by the invention can be independently and locally applied. The acupoint application can be used for biological regulation of skin and acupoints, promoting topical microcirculation improvement, and promoting nodule dissipation and absorption. On the basis of using the oral preparation provided by the invention, the external preparation provided by the invention is applied locally to the severe or malignant thyroid nodule and thyroiditis complicated with thyroid dysfunction, so that the external preparation can directly reach the focus, the local symptoms and the nodule can be quickened to subside, the clinical curative effect is enhanced, and the effective rate of disease treatment is improved.
Thyroid diseases correspond to "goiter" in traditional Chinese medicine. Goiter is a general term for lump diseases occurring on both sides of the anterior cervical junction, and is clinically characterized in that both sides of the anterior cervical junction are diffusely swollen or agglomerated, and can move up and down along with swallowing actions. The traditional Chinese medicine considers that qi, fire, phlegm and blood stasis are important pathological factors of thyroid nodule and penetrate through the whole disease process. The applicant uses the general regulation method to treat liver, spleen and kidney dysfunction and qi fire phlegm stasis, combines two treatment means of oral administration and external application, treats thyroid nodule simultaneously, or only uses external application for treating mild patients, and proves that the clinical curative effect is safe and reliable through a great deal of clinical practice verification. Therefore, the invention provides basis and foundation for the abundant theory of traditional Chinese medicine and a great deal of clinical practice as support.
The invention has the following advantages:
1. the traditional Chinese medicine composition for treating thyroid diseases provided by the invention has the advantages that honeysuckle can clear away heat and toxic materials and disperse wind and heat; fructus forsythiae has effects of clearing heat and detoxicating, detumescence and resolving hard mass, dispelling pathogenic wind and heat, and the above two medicines are all monarch medicines; melon basket has effects of clearing heat, eliminating phlegm, relieving chest stuffiness, resolving hard mass, loosening bowel, and relieving constipation; radix Ranunculi Ternati has effects of removing toxic substance, eliminating phlegm, softening hard mass, and resolving hard mass; zhejiang Bei Qingre, resolving phlegm, softening hardness and resolving masses; the selfheal can clear heat and purge fire, dissipate stagnation and reduce swelling, and the four medicines are used as ministerial medicines; red peony root has the functions of clearing heat, cooling blood, dispersing blood stasis and relieving pain; the salvia miltiorrhiza has the effects of activating blood circulation to regulate menstruation, removing stasis to relieve pain, cooling blood to remove carbuncle, and the radix scrophulariae has the effects of clearing heat to cool blood, purging pathogenic fire to remove toxin and nourishing yin; zedoary has the effects of breaking blood, promoting qi circulation, removing food retention and relieving pain; the frankincense has the effects of activating blood circulation, relieving pain, reducing swelling and promoting tissue regeneration; the myrrh has the functions of promoting blood circulation, relieving pain, detumescence and promoting tissue regeneration, and the six medicines are used as adjuvant medicines. The traditional Chinese medicine composition provided by the invention has the advantages of definite curative effect, safety, reliability, rapid alleviation of illness state and excellent service for patients.
2. The traditional Chinese medicinal materials used in the traditional Chinese medicinal composition for treating thyroid diseases are all common nontoxic traditional Chinese medicines, are safe and reliable, have a simple preparation method, are pollution-free to the environment, and have great popularization and application values.
Detailed Description
Other advantages and advantages of the present invention will become apparent to those skilled in the art from the following detailed description, which, by way of illustration, is to be read in connection with certain specific embodiments, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The medicinal materials used in the embodiment of the invention are all commercial products.
Unless specifically indicated, the technical means used in the embodiments of the present invention are conventional means well known to those skilled in the art.
Example 1
The embodiment provides a traditional Chinese medicine composition for treating thyroid diseases, which comprises 10 parts of honeysuckle, 10 parts of weeping forsythia, 30 parts of melon basket, 10 parts of catclaw grass, 15 parts of thunberg fritillary bulb, 10 parts of selfheal, 10 parts of red paeony root, 25 parts of red sage root, 20 parts of figwort root, 10 parts of zedoary, 10 parts of frankincense and 10 parts of myrrh.
Example 2
The embodiment provides a traditional Chinese medicine composition for treating thyroid diseases, which comprises 15 parts of honeysuckle, 20 parts of fructus forsythiae, 30 parts of fructus trichosanthis, 15 parts of radix ranunculi ternati, 15 parts of fritillaria thunbergii, 15 parts of selfheal, 15 parts of radix paeoniae rubra, 30 parts of radix salviae miltiorrhizae, 30 parts of radix scrophulariae, 10 parts of rhizoma curcumae, 10 parts of frankincense and 10 parts of myrrh.
Example 3
The embodiment provides a traditional Chinese medicine composition for treating thyroid diseases, which comprises 15 parts of honeysuckle, 15 parts of fructus forsythiae, 30 parts of fructus trichosanthis, 15 parts of radix ranunculi ternati, 15 parts of Bulbus Fritillariae Thunbergii, 15 parts of selfheal, 15 parts of radix paeoniae rubra, 30 parts of radix salviae miltiorrhizae, 30 parts of radix scrophulariae, 15 parts of rhizoma curcumae, 15 parts of frankincense and 15 parts of myrrh.
Example 4
The embodiment provides a preparation method of a decoction medicine for treating thyroid diseases, which comprises the following steps:
the Chinese medicinal composition of example 1 is soaked in water for 2h, then extracted under reflux for 2 times, and the extracts are combined to obtain decoction.
Example 5
The embodiment provides a preparation method of a granule medicine for treating thyroid diseases, which comprises the following steps:
the Chinese medicinal composition of example 2 was soaked in water for 2h, then extracted 2 times under reflux, the extracts were combined, concentrated, starch was added to the extract, and granules were prepared according to the conventional method in the art.
Example 6
The embodiment provides a preparation method of a patch medicine for treating thyroid diseases, which comprises the following steps:
the traditional Chinese medicine composition of the embodiment 3 is prepared by crushing, sieving with a 100-mesh sieve, adding distilled spirit accounting for 20% of the total mass of the raw materials and vaseline accounting for 20% of the total mass of the raw materials, blending into paste, and filling into a plaster.
Effect verification
(1) The clinical data is 60 cases of thyroid nodule patients from the clinic 1 month in 2020 to 1 month in 2021, and the treatment is randomly divided into 1-3 groups, wherein 20 cases of thyroid nodule patients in each group are treated by the traditional Chinese medicine composition of the embodiment 1-3 respectively for 1-3 groups, and the treatment time is 3 months (one treatment course). Observing symptoms before and after treatment, detecting thyroid function and thyroid color Doppler ultrasound, and evaluating curative effect; detecting blood routine, liver function and kidney function, and performing safety evaluation.
(2) The diagnosis standard is prepared by referring to China's header "diagnosis and treatment guidelines for thyroid nodule and differentiated thyroid cancer" which are jointly compiled by the national health publishing society 2018 (ninth edition) and the China's China medical society endocrinology and science conference, the China's society of surgery and head and neck tumor professional committee of China's anticancer society, and the China's society of nuclear medicine conference:
(1) medical history: the onset of the disease is hidden, the disease course is different, and the disease is not easy to be found.
(2) Symptoms: most cases have no clinical manifestations, and when thyroid dysfunction is combined, symptoms of hyponychium such as hypodynamia, inappetence and the like can appear, or clinical manifestations of hyperthyroidism such as palpitation, tremble hands, hyperhidrosis and emaciation can appear. Some patients have symptoms of oppression and discomfort of neck, hoarseness, compressed air feeling, unsmooth breathing, dysphagia and the like, which are caused by the fact that the nodule is enlarged to press surrounding tissues. When inflammation, hemorrhage or cancer occurs, there may be local symptoms such as neck pain and tenderness, and systemic manifestations such as fever.
(3) The physical sign is as follows: palpation can detect one or more tumors in the thyroid gland on one side or both sides, and can move up and down with swallowing movements.
(4) Auxiliary inspection: thyroid ultrasound examination can discover the presence of one or more nodules within the thyroid gland and determine the location, texture, shape, clarity of the boundaries, integrity of the envelope, presence of calcification foci, and blood supply around and within the nodules. Thyroid function examination may be in the presence of elevated, normal or reduced TSH, TGAb, TPOAb may be negative or positive.
(3) The diagnosis standard of the Chinese medicine syndrome refers to the national standard of the people's republic of China, the Chinese medicine clinical diagnosis and treatment terminology and syndrome section (GB/T16751.2-1997), and the Chinese medicine syndrome type is determined to be qi stagnation, phlegm coagulation and blood stasis type.
(4) The curative effect is comprehensively evaluated according to the changes of main symptoms and signs before and after the treatment of patients:
traditional Chinese medicine syndrome curative effect judgment standard: formulation by referring to the 2002' guidelines for clinical research on New Chinese medicine
Clinical recovery: the clinical symptoms and signs of the traditional Chinese medicine disappear or basically disappear, and the integral of symptoms is reduced by more than or equal to 95 percent.
The effect is shown: the clinical symptoms and signs of the traditional Chinese medicine are obviously improved, and the integral of symptoms is reduced by more than or equal to 70 percent and is less than 95 percent;
the method is effective: the clinical symptoms and signs of the traditional Chinese medicine are all improved, and the integral of symptoms is reduced by more than or equal to 30 percent and is less than 70 percent;
invalidation: the clinical symptoms and physical signs of the traditional Chinese medicine are not obviously improved or even aggravated, and the integral of symptoms is reduced by less than 30 percent.
Note that: calculation formula (nimodipine method): [ integration before treatment-integration after treatment ]
Total effective rate= (clinical cure + onset + efficacy)/total number of cases 100%.
(5) Therapeutic results
The results show that each group of treatment achieves better clinical effects, wherein the traditional Chinese medicine composition of the embodiment 3 has more remarkable effects in improving symptoms and preventing the development of thyroid nodules. See table 1:
table 1 comparison of clinical efficacy of internal and external treatment groups and Chinese medicine oral administration group
(6) Adverse reactions
None of the patients in the treatment groups 1-3 showed serious adverse reactions, of which 3 showed skin allergic reactions during the use of the external patch, and were relieved by themselves without special treatment, and no other reactions were found.
Typical case
1. Su somebody, a woman, 70 years old. Initial diagnosis time: 2021, 5 and 9. The self-complaining thyroid gland has 3 nodules, has obvious blocking feeling during eating, is dry in mouth, can be used for receiving, is not good enough to sleep, is difficult to sleep, is easy to wake, has chest distress, shortness of breath, debilitation, acid sinking and pain in shoulder and back, is sometimes easy to have abdominal distension, is untimely and easy to sweat, is slightly impatient in eating, is difficult to defecate, is sticky in stool, depends on the soup for tonifying middle-jiao and Qi for a long time, and has the effects of tonifying middle-jiao and Qi, tonifying and defecating and relieving weakness. Auxiliary inspection: thyroid has 3 nodules of unequal size, 1.7X1.4 cm each; 0.5X0.3 cm; 0.7X0.4 cm. First work inspection: t31.18 ∈ (1.3-3.1) nmol/L, TG 84.9 ∈ (3.5-77) μg/L, and the rest is normal. Diagnosis: hashimoto thyroiditis; reducing first; thyroid nodule; syndrome differentiation: syndrome of yin deficiency and phlegm-heat.
Treatment: the Chinese medicinal composition of example 3 was used for oral and topical application and ordered patients to have less spicy irritation, barbecue frying and seafood. After 3 months of treatment, a review of the B-ultrasound shows: 2 out of 3 nodules disappeared, and only one large nodule remained, also shrinking from 1.7X1.4 cm to 1.0X10.8 cm. And (5) rechecking the first-class work display: TG returns to normal, T3.19 ∈ (1.3-3.1) nmol/L. The patient has no eating obstruction, no dry mouth, sleep, chest distress, short breath, and pain relieving, night sweat relieving, and stable emotion; the frequency of the vector qi improves. The stool is smooth, 1 time a day, and the urine is normal.
2. Somewhere in Lu, men, 42 years old. Initial diagnosis time: 8.11.2019. The main complaints are: heat was generated for 1 week. The patient has sore throat after 7 months, left neck is swollen, throat pain, fever appears in the near week, the body temperature is 38.5-38.9 ℃, cough, neck swelling, tightness and weakness are caused. Auxiliary inspection: 63.8mg/L ≡C-reactive protein; blood sedimentation: 62mm/1hr ≡; first work: TSH <0.005 ∈mIU/L; FT 3.70 ∈pmol/L (3.1-6.8); FT 4.66 ∈pmol/L (12-22), and the remainder is normal; thyroid color ultrasound examination: thyromegaly, right She Houyao 2.4cm, left She Houyao 2.4.4 cm, isthmus thickness about 0.6cm, 3 nodules of unequal size appear in the thyroid gland, respectively: 2.3X1.3 cm (left leaf bottom pole), 2.3X1.4cm (right leaf middle), 0.7X10.7X10.5 cm (right leaf top pole). Diagnosis: subacute thyroiditis; syndrome differentiation: syndrome of phlegm-fire stasis.
Treatment: the Chinese medicinal composition of example 3 was used for oral and topical administration and patients were prescribed a lot of rest. After 4 months of treatment, the first function is recovered to be normal, and ultrasonic examination shows that: the thyroid size is recovered to be normal, and thyroid multiple nodules are reduced, which are respectively: 0.7X0.4 cm (right leaf top pole), 0.3X0.3 cm (left leaf bottom pole); 0.2cm calcification foci (right leaf bottom). Thyroid gland echo was locally reduced, and changes after treatment of methylene inflammation were considered in combination with medical history. Laboratory examination: the alpha function, the C reaction protein, the blood sedimentation and the like are recovered to be normal. The body temperature of the patient is recovered to be normal, the cough is eliminated, the pharyngalgia is eliminated, the neck swelling and pain is eliminated, the tightness is eliminated, the weakness is not obvious, and the urination is normal.
3. Somebody, men, 54 years old. Initial diagnosis time: 2021, 1 and 22 days. The following sizes are respectively that 2 thyroid nodules are found in the examination of 2019: 2.8X1.5 cm; 0.3X0.2 cm. The first-order work 7 items are all normal. Subjective neck distending pain, phlegm in the pharynx, yellow phlegm in the morning, foreign body sensation in the pharynx, dry mouth, bitter taste in mouth, sticky mouth, more gum, irritability, debilitation, insomnia, dry stool and 1 time in 1 day. Diagnosis: nodular goiter; syndrome differentiation: syndrome of yin deficiency and phlegm-heat.
Treatment: the Chinese medicinal composition of example 3 is used for oral administration and external application, and patients are ordered to eat less spicy stimulation, barbecue frying, oily food and drink less. After 7 months of treatment, a review of the B-ultrasound shows: 1 out of 2 nodules disappeared, and only 1 large nodule remained was also reduced from 2.8X1.5 cm to 2.2X1.1X1.3 cm. The symptoms of the whole body are improved, the distending pain of the neck is basically eliminated, the swelling pain is sometimes caused for 1-2 days, the sputum is gradually reduced, the foreign body sensation is eliminated, the mouth is sticky, the mouth is dry, the mouth is bitter and improved, the eye is reduced, the emotion is gradually stable, the symptoms of weakness are not obvious, and the patient can sleep and relieve oneself.
While the invention has been described in detail in the foregoing general description and specific examples, it will be apparent to those skilled in the art that modifications and improvements can be made thereto. Accordingly, such modifications or improvements may be made without departing from the spirit of the invention and are intended to be within the scope of the invention as claimed.
Claims (8)
1. The traditional Chinese medicine composition for treating thyroid nodule is characterized by comprising the following raw materials in parts by weight: 10-20 parts of honeysuckle, 10-20 parts of weeping forsythia, 20-40 parts of snakegourd fruit, 10-20 parts of radix ranunculi ternati, 10-20 parts of thunberg fritillary bulb, 10-20 parts of selfheal, 10-20 parts of red paeony root, 20-40 parts of red sage root, 20-40 parts of figwort root, 10-20 parts of curcuma zedoary, 10-20 parts of frankincense and 10-20 parts of myrrh.
2. The traditional Chinese medicine composition for treating thyroid nodule according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 12-18 parts of honeysuckle, 12-18 parts of weeping forsythia, 24-36 parts of snakegourd fruit, 12-18 parts of radix ranunculi ternati, 12-18 parts of thunberg fritillary bulb, 12-18 parts of selfheal, 12-18 parts of red paeony root, 24-36 parts of red sage root, 24-36 parts of figwort root, 12-18 parts of curcuma zedoary, 12-18 parts of frankincense and 12-18 parts of myrrh.
3. The traditional Chinese medicine composition for treating thyroid nodule according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 14-16 parts of honeysuckle, 14-16 parts of weeping forsythia, 28-32 parts of snakegourd fruit, 14-16 parts of radix ranunculi ternati, 14-16 parts of fritillaria thunbergii, 14-16 parts of selfheal, 12-18 parts of red paeony root, 28-32 parts of red sage root, 28-32 parts of figwort root, 14-16 parts of rhizoma curcumae, 14-16 parts of frankincense and 14-16 parts of myrrh.
4. The traditional Chinese medicine composition for treating thyroid nodule according to any one of claims 1-3, wherein the traditional Chinese medicine composition further comprises pharmaceutically acceptable excipients.
5. The traditional Chinese medicine composition for treating thyroid nodule according to claim 4, wherein the dosage form of the traditional Chinese medicine composition comprises decoction, granule, pill, tablet, powder, ointment and patch.
6. The method for preparing the traditional Chinese medicine composition for treating thyroid nodule according to any one of claims 1 to 5, wherein the dosage form of the traditional Chinese medicine composition is a patch, and the preparation method comprises the following steps:
weighing the raw materials according to the formula, pulverizing, sieving with 80-100 mesh sieve, adding white wine and vaseline, concocting into paste, and packaging into adhesive plaster.
7. The method for preparing a traditional Chinese medicine composition for treating thyroid nodule according to claim 6, wherein the addition amount of the white spirit is 15-25% of the total mass of the raw materials.
8. The method for preparing a traditional Chinese medicine composition for treating thyroid nodule according to claim 6, wherein the addition amount of the vaseline is 15-25% of the total mass of the raw materials.
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| CN109833417A (en) * | 2017-11-27 | 2019-06-04 | 田启旺 | The composition and preparation method thereof for treating thyroiditis |
| CN113599481A (en) * | 2021-09-24 | 2021-11-05 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating thyroid diseases and preparation method and application thereof |
| CN114306206A (en) * | 2021-12-28 | 2022-04-12 | 苏州市中医医院 | External traditional Chinese medicine composition for treating thyroid nodule and preparation method and application of external traditional Chinese medicine gel plaster |
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| CN109833417A (en) * | 2017-11-27 | 2019-06-04 | 田启旺 | The composition and preparation method thereof for treating thyroiditis |
| CN113599481A (en) * | 2021-09-24 | 2021-11-05 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating thyroid diseases and preparation method and application thereof |
| CN114306206A (en) * | 2021-12-28 | 2022-04-12 | 苏州市中医医院 | External traditional Chinese medicine composition for treating thyroid nodule and preparation method and application of external traditional Chinese medicine gel plaster |
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| Title |
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| 中西医结合治疗亚急性甲状腺炎30例;代莲等;福建中医药;-;第46卷(第6期);7-8 * |
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