CN109820780A - It is a kind of to treat acne face cleaning gel and preparation method thereof - Google Patents

It is a kind of to treat acne face cleaning gel and preparation method thereof Download PDF

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Publication number
CN109820780A
CN109820780A CN201910189828.9A CN201910189828A CN109820780A CN 109820780 A CN109820780 A CN 109820780A CN 201910189828 A CN201910189828 A CN 201910189828A CN 109820780 A CN109820780 A CN 109820780A
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China
Prior art keywords
glycerol
extract
ester
acrylic acid
potassium hydroxide
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Withdrawn
Application number
CN201910189828.9A
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Chinese (zh)
Inventor
陈诗颖
黄惠先
杨郑琪
江华初
黄君如
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Guangzhou Cohen Biotechnology Co Ltd
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Guangzhou Cohen Biotechnology Co Ltd
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Priority to CN201910189828.9A priority Critical patent/CN109820780A/en
Publication of CN109820780A publication Critical patent/CN109820780A/en
Withdrawn legal-status Critical Current

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Abstract

It is a kind of to treat acne face cleaning gel and preparation method thereof, it is made of the following components: acrylic acid (ester) analog copolymer, laureth ammonium sulfate, cocamidopropyl propyl amide hydroxyl sulfobetaines, glycerol, coconut oleoyl amine MEA, mint extract, potassium hydroxide, purslane extract, tuckahoe extracts, pungent glycol, Chiba rose hydrosol.Preparation method includes the following steps: (1) precise each component is spare according to the ratio;(2) acrylic acid (ester) analog copolymer, the poly- ammonium sulfate of laruyl alcohol, cocamidopropyl propyl amide hydroxyl sulfobetaines, glycerol and Chiba rose hydrosol are added in emulsion pot and are mixed;(3) vacuumizing and defoaming;(4) it stirs and cooling;(5) coconut oleoyl amine MEA and potassium hydroxide, pungent glycol, mint extract, purslane extract, tuckahoe extracts is added, discharges after stirring is cooling.The present invention has positive effect to acne treatment.

Description

It is a kind of to treat acne face cleaning gel and preparation method thereof
Technical field
The present invention relates to cosmetic technical field more particularly to a kind of treat acne face cleaning gel and preparation method thereof.
Background technique
Acne is a kind of chronic inflammatory skin of pilosebaceous unit, is mainly apt to occur in teenager, clinical manifestation With the characteristics of being apt to occur in the pleomorphism skin lesions such as facial acne, papule, warts, tubercle, inflammatory skin lesion is usually left after subsiding Pigmentation, erythema perstans, pitting or hypertrophic scar are very big to teen-age psychology and social influence.
Current product for resolving poxes many on the market are all made an overstatement, and actual effect then very little or to no effect, some is even also It can deepen the state of an illness, the pursuit with people for beauty increasingly increases severely for the demand of a product with good anti-acne effect.
The present invention uses anhydrous formulations, improves the big problem of the irritation generated in formula by the permeability of water, together When the theory based on the customization of private gene, cooperate personal five big dimension, that is, regions, age, season, genetic test, cutaneous manifestations Physiological data and pathology data allow user to have the Product Experience as accurate skin care, personal customization.
Summary of the invention
In view of the deficiencies of the prior art, technical problem solved by the invention is treatment acne, is repaired to skin condition It is multiple.
In order to solve the above technical problems, the technical solution adopted by the present invention is that a kind of treat acne face cleaning gel, by following Constituent mass percentage is made: acrylic acid (ester) analog copolymer 8%-12%, laureth ammonium sulfate 8%-10%, cocounut oil acyl Amine propyl hydroxy sulfobetaines 6%-9%, glycerol 3%-7%, coconut oleoyl amine MEA0.5%-1.5%, mint extract 1%- 2%, potassium hydroxide 0.3%-0.5%, purslane extract 2%-4%, tuckahoe extracts 0.5%-1.0%, pungent glycol 0.2%-0.8%, Chiba rose hydrosol 58%-65%.
The invention solves another technical problem be to provide the preparation method of above-mentioned treatment acne face cleaning gel.
For this purpose, technical solution provided by the invention is a kind of preparation method for treating acne face cleaning gel, including following step It is rapid:
(1) component precise acrylic acid (ester) analog copolymer, laureth ammonium sulfate, cocamidopropyl propyl amide hydroxyl are pressed Sulfobetaines, glycerol, coconut oleoyl amine MEA, mint extract, potassium hydroxide, purslane extract, tuckahoe extracts, Xin Gan Alcohol, Chiba rose hydrosol are spare;
(2) it is added in emulsion pot after being uniformly mixed acrylic acid (ester) analog copolymer, it is poly- to sequentially add laruyl alcohol Ammonium sulfate, cocamidopropyl propyl amide hydroxyl sulfobetaines, glycerol and Chiba rose hydrosol, are warming up to 80 DEG C, and 30 turns of mixing speed/ Minute;
(3) 30 minutes are kept the temperature, vacuumizes 0.05mmHg (Pa) deaeration;
(4) 40 revs/min of mixing speed and 40 DEG C are cooled to;
(5) coconut oleoyl amine MEA and potassium hydroxide is added, stirs 20 minutes, is cooled to 40 DEG C and pungent glycol, peppermint extraction is added Object, purslane extract, tuckahoe extracts, discharging obtains finished product after twenty minutes for stirring.
Compared with prior art, the invention has the benefit that
(1) main component in Poria cocos is pachyman, and content is very high, has inhibiting effect to various bacteria, can be many-sided Immune function is adjusted, scientific investigations showed that: 100% decoction of Poria cocos with plate burrow method to staphylococcus aureus, Escherichia coli, proteus etc. have inhibiting effect, have good antibacterial, antiinflammation to skin surface;
(2) volatile oil in peppermint and flavone compound etc. have apparent antibacterial, anti-inflammatory effects, while to skin scabies Itching also has good relaxation effect;
(3) a large amount of Flavonoid substances contained in purslane extract have chafing, suppuration good slow Solution effect, can promote the healing of acne;
(4) deionized water is replaced using Chiba rose hydrosol, face cleaning gel is made to have both treatment acne, healthy skin of releiving Effect.
Specific embodiment
A specific embodiment of the invention is further described below with reference to embodiment, but is not to limit of the invention It is fixed.
Embodiment 1:
It is a kind of to treat acne face cleaning gel, it is made of following components mass percent: acrylic acid (ester) analog copolymer 12%, Laureth ammonium sulfate 10%, cocamidopropyl propyl amide hydroxyl sulfobetaines 7.7%, glycerol 7%, coconut oleoyl amine MEA 0.8%, mint extract 1%, potassium hydroxide 0.5%, purslane extract 2%, tuckahoe extracts 0.5%, pungent glycol 0.5%, Chiba rose hydrosol 58%.
Embodiment 2:
It is a kind of to treat acne face cleaning gel, it is made of following components mass percent: acrylic acid (ester) analog copolymer 10%, Laureth ammonium sulfate 8%, cocamidopropyl propyl amide hydroxyl sulfobetaines 7%, glycerol 7%, coconut oleoyl amine MEA 0.8%, Mint extract 2%, potassium hydroxide 0.5%, purslane extract 4%, tuckahoe extracts 0.5%, pungent glycol 0.5%, Chiba Rose 59.7%.
Embodiment 3:
It is a kind of to treat acne face cleaning gel, it is made of following components mass percent: acrylic acid (ester) analog copolymer 8%, Laureth ammonium sulfate 7%, cocamidopropyl propyl amide hydroxyl sulfobetaines 7%, glycerol 4.2%, coconut oleoyl amine MEA 0.8%, mint extract 2%, potassium hydroxide 0.5%, purslane extract 4%, tuckahoe extracts 1%, pungent glycol 0.5%, Chiba rose hydrosol 65%.
1 to 3 preparation method of above-described embodiment, is made up of following steps:
(1) by formula precise acrylic acid (ester) analog copolymer, laureth ammonium sulfate, cocamidopropyl propyl amide hydroxyl Sulfobetaines, glycerol, coconut oleoyl amine MEA, mint extract, potassium hydroxide, purslane extract, tuckahoe extracts, Xin Gan Alcohol, Chiba rose hydrosol are spare;
(2) it is added in emulsion pot after being uniformly mixed acrylic acid (ester) analog copolymer, it is poly- to sequentially add laruyl alcohol Ammonium sulfate, cocamidopropyl propyl amide hydroxyl sulfobetaines, glycerol and Chiba rose hydrosol, are warming up to 80 DEG C, and 30 turns of mixing speed/ Minute;
(3) 30 minutes are kept the temperature, vacuumizes 0.05mmHg (Pa) deaeration;
(4) 40 revs/min of mixing speed and 40 DEG C are cooled to;
(5) coconut oleoyl amine MEA and potassium hydroxide is added, stirs 20 minutes, is cooled to 40 DEG C and pungent glycol, peppermint extraction is added Object, purslane extract, tuckahoe extracts, discharging obtains finished product after twenty minutes for stirring.
Beneficial effect in order to better illustrate the present invention carries out efficacy assessments experiment:
By to staphylococcus aureus ATCC 6538, Pseudomonas aeruginosa ATCC 9027, Escherichia coli ATCC8739, white Candida albicans ATCC 10231, microsporon furfur, propionibacterium acnes bacteriostatic experiment, efficacy assessments are divided into three-level: it is effective, It is effectively and invalid.Be determined as when cosmetics are all larger than equal to 90% above-mentioned strain bacteriostasis rate it is effective, when to first three strain Fungistatic effect is more than or equal to 90% and is determined as when being more than or equal to 50%-90% to latter three kinds effectively, as long as to rear three kinds of strains When bacteriostasis rate is less than 50%, then it is invalid to be determined as.
Culture medium and condition of culture:
(37 DEG C, 48h culture, are used for staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli to ordinary nutrient agar culture medium Culture);Sabouraud's agar (30 DEG C, 3 days are cultivated, and Candida albicans culture is used for);Improvement is husky to protect Ruo Shi agar medium (30 DEG C, 3 days are cultivated, and microsporon furfur culture is used for): dextrose broth (37 DEG C, 48h Anaerobic culturel, in acne Acidfast bacilli culture).
Operating procedure:
(1) test organisms for 24 hours washed down with 0.03ml/L PBS by (bacterium) and 5 days (fungi) cultures, and 10cfu/mL bacterium is made Suspension;
(2) it takes and above-mentioned bacteria suspension 0.1mL even spread mixing is added by test agent 1g, after starting timing 20min, be added 9mL 0.03mol/L PBS is mixed well, and after making appropriate dilution, takes wherein 2-3 dilutions, 1mL is taken to be placed in two respectively In parallel plate, corresponding culture medium difference Hybrid NC machine tool is added.Make colony count.The above test is repeated 3 times, and takes it average Number, while setting blank control, calculates: X=(A-B)/Ax100%, and in formula: X bacteriostasis rate, mono- control sample of %, A averagely recycle bacterium It falls, mono- test specimen of B averagely recycles bacterium colony;
(3) result reports that bacteriostasis rate >=50%-90%, product have bacteriostasis;Bacteriostasis rate >=90%, product have stronger suppression Bacterium effect.
The experimental results are shown inthe following table:
Strain Bacteriostasis rate
Staphylococcus aureus ATCC 6538 >=90%
Pseudomonas aeruginosa ATCC 9027 >=90%
Escherichia coli ATCC 8739 >=90%
Candida albicans ATCC 10231 >=50%-90%
Microsporon furfur >=50%-90%
Propionibacterium acnes >=50%-90%
As seen from the above table, the present invention is all larger than equal to 90% first three strain bacteriostasis rate, and to latter three kinds be greater than etc. In 50%-90%, shows that the present invention is effective effect to acne treatment, there is obvious gain effect.
Detailed description is made that embodiments of the present invention in conjunction with the embodiments above, but the present invention be not limited to it is described Embodiment.To those skilled in the art, without departing from the principles and spirit of the present invention, to these realities The mode of applying carries out various change, modification, replacement and variant are still fallen in protection scope of the present invention.

Claims (3)

1. a kind of treat acne face cleaning gel, which is characterized in that be made of following components mass percent: acrylic acid (ester) class is total Polymers 8%-12%, laureth ammonium sulfate 8%-10%, cocamidopropyl propyl amide hydroxyl sulfobetaines 6%-9%, glycerol 3%-7%, coconut oleoyl amine MEA 0.5%-1.5%, mint extract 1%-2%, potassium hydroxide 0.3%-0.5%, purslane Extract 2%-4%, tuckahoe extracts 0.5%-1.0%, pungent glycol 0.2%-0.8%, Chiba rose hydrosol 58%-65%.
2. treatment acne face cleaning gel according to claim 1, which is characterized in that by following components mass percent system At: acrylic acid (ester) analog copolymer 10%, laureth ammonium sulfate 8%, cocamidopropyl propyl amide hydroxyl sulfobetaines 7%, Glycerol 7%, coconut oleoyl amine MEA 0.8%, mint extract 2%, potassium hydroxide 0.5%, purslane extract 4%, Poria cocos mention Take object 0.5%, pungent glycol 0.5%, Chiba rose hydrosol 59.7%.
3. a kind of preparation method for the treatment of acne face cleaning gel as claimed in claim 1 or 2, which is characterized in that including following Step:
(1) component precise acrylic acid (ester) analog copolymer, laureth ammonium sulfate, cocamidopropyl propyl amide hydroxyl sulfenyl are pressed Glycine betaine, glycerol, coconut oleoyl amine MEA, mint extract, potassium hydroxide, purslane extract, tuckahoe extracts, pungent glycol, thousand Leaf rose is spare;
(2) it is added in emulsion pot after being uniformly mixed acrylic acid (ester) analog copolymer, sequentially adds laruyl alcohol polysulfide acid Ammonium, cocamidopropyl propyl amide hydroxyl sulfobetaines, glycerol and Chiba rose hydrosol are warming up to 80 DEG C, 30 revs/min of mixing speed Clock;
(3) 30 minutes are kept the temperature, vacuumizes 0.05mmHg (Pa) deaeration;
(4) 40 revs/min of mixing speed and 40 DEG C are cooled to;
(5) coconut oleoyl amine MEA and potassium hydroxide is added, stirs 20 minutes, be cooled to 40 DEG C be added pungent glycol, mint extract, Purslane extract, tuckahoe extracts, discharging obtains finished product after twenty minutes for stirring.
CN201910189828.9A 2019-03-13 2019-03-13 It is a kind of to treat acne face cleaning gel and preparation method thereof Withdrawn CN109820780A (en)

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Application Number Priority Date Filing Date Title
CN201910189828.9A CN109820780A (en) 2019-03-13 2019-03-13 It is a kind of to treat acne face cleaning gel and preparation method thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113332215A (en) * 2021-07-23 2021-09-03 王涛 Composition preparation for treating acne and resisting allergy and preparation process

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113332215A (en) * 2021-07-23 2021-09-03 王涛 Composition preparation for treating acne and resisting allergy and preparation process

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Application publication date: 20190531

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