CN109805037A - A kind of print chinaberry mite killing, fungicide and its preparation method and application - Google Patents
A kind of print chinaberry mite killing, fungicide and its preparation method and application Download PDFInfo
- Publication number
- CN109805037A CN109805037A CN201910144361.6A CN201910144361A CN109805037A CN 109805037 A CN109805037 A CN 109805037A CN 201910144361 A CN201910144361 A CN 201910144361A CN 109805037 A CN109805037 A CN 109805037A
- Authority
- CN
- China
- Prior art keywords
- fungicide
- mite killing
- print chinaberry
- killing
- mite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention belongs to fungicide field, a kind of print chinaberry mite killing, fungicide and its preparation method and application are disclosed, chinaberry mite killing, fungicide is printed, contains neem extract.Preparation method includes the following steps: step 1: neem kernel being cleaned, low temperature drying, crushed 16 meshes；Step 2: the neem kernel powder of crushing is packed into hollow glass column, is extracted 3 times with n-hexane, and rotary evaporation removes n-hexane under the conditions of 40 DEG C, obtains substance a；Step 3: by the substance a with there is pump to remove residual solvent, containing oil soluble active insecticidal components is obtained and are compounded to obtain mite killing, fungicide.The present invention is directed to the life habit of acarid, and the feature nontoxic and without secondary pollution using natural plant extracts is realized and killed to human body acarid, reduces the influence to human health.Used plant extracts has the characteristics that anti-inflammation and sterilization, after without skin allergy, rest on skin surface while killing acarid can also pre- anti-mite regeneration.
Description
Technical field
The invention belongs to fungicide field, in particular to a kind of print chinaberry mite killing, fungicide and its preparation method and application.
Background technique
One kind that acarid belongs to Arthropoda Arachnoidea Acari has communicable figure animalcule, and body is big
Small general all in 0.5 mm or so, some are small to 0.1 mm, and most of types are less than 1 mm.Known mite class type is about in the world
There are more than 30000 kinds, is under the jurisdiction of 2 mesh, 6 suborders, 105 Superfamilys, 380 sections respectively, is only second to insect.Colonize in people
The acarid of body is broadly divided into two kinds, and one is follicle mites, also cries people vermiform mite；Another kind is named sebaceous glands mite, colonizes in human face
Sebaceous glands in, it is general also just referred to as acarid.
Acarid is distributed widely in mankind's environment placed in the middle, very close with human health, acarid also become after fly,
The another big insect pest of human health is endangered after flea.After invermination, obstruction, secretion, chitin shell of polypide etc. can
Cause hair follicle expansion, acne, epifolliculitis, brandy nose, demodicidosis, allergy etc., it can also be the virus of skin surface, bacterium, vertical
Gram time body, conveyor screw and protozoon etc. bring hair follicle depths into, cause inflammation, lead to skin early ageing, cause to the health of the mankind
Serious harm.
Currently, mainly using the strategy of integrated control for the prevention and treatment of acarid, basic principle is to put prevention first, Synthetic
Reason, treating both manifestation and root cause of disease are emphasized to effect a permanent cure, and control the harm of acarid.Main control method has environment prevention and treatment, physical control and chemistry anti-
It controls.Presently relevant mite killing product mainly has mite killing aerosol, mite killing perfumed soap, air-conditioning mite killing cleaning agent, mite killing washing powder etc., this
The main component of a little products is avermectin, Ivermectin HCL preparation, pyrethroid ester formulation, acaricide propargite, bromine mite is special, rattles away
Mite spirit, Ergol and fumigant etc..These chemical reagent components are as mite-killing preparation, and to human health, there are certain wind
Danger.
Acarid mainly colonizes in humans and animals body surface, is the last line of defense that human body is taught.How human body is being ensured
It is current urgent problem to be solved that acarid is killed while healthy.Therefore, it is badly in need of a kind of healthy, efficiently, environmentally friendly mite killing mode
To ensure human health.
Summary of the invention
An object of the present invention be solve the problems of in the prior art, and then provide a kind of print chinaberry mite killing,
Fungicide and its preparation method and application.
To solve the above problems, adopting the following technical scheme that:
A kind of print chinaberry mite killing, fungicide, containing neem extract and stabilizer, the stabilizer include citric acid, vitamin E and
Arabo-ascorbic acid.
Further, the mite killing, bacteriocide formula are as follows: 5% citric acid, 5% vitamin E, 5% arabo-ascorbic acid and 85% print
Chinaberry extract.
Further, the neem extract is the mixture of nim oil and germicide-acaricide active constituent.
Further, the dosage form of the print chinaberry fungicide can be missible oil, microemulsion, arbitrary a kind of in aqueous emulsion.
Above-mentioned print chinaberry mite killing, the method for fungicide are prepared, is included the following steps:
Step 1: neem kernel is cleaned, low temperature drying, crushed 16 meshes；
Step 2: the neem kernel powder of crushing being packed into hollow glass column, is extracted with n-hexane, rotary evaporation removal just oneself
Alkane obtains substance a；
Step 3: by substance a that the step 2 obtains with there is pump to remove residual solvent, obtain containing oil soluble insecticidal activity at
The extract b divided；
Step 4: the extract b that the step 3 obtains is compounded, mite killing, fungicide are obtained.
Further, the n-hexane in the step 2 is HPLC grades, is extracted 3 times, and rotating evaporation temperature is 35 ~ 45 DEG C.
Further, the compounding in the step 4 is that stabilizer: citric acid, vitamin E and arabo-ascorbic acid is added.
Further, the ingredient of the step 4 obtains mite killing, fungicide are as follows: 5% citric acid, 5% vitamin E, 5% different
Ascorbic acid and 85% neem extract.
A kind of above-mentioned print chinaberry mite killing, the purposes of fungicide are added to washing powder, in hand cleanser in mass ratio 1% ~ 3%,
It can be applied to humans and animals body surface, clothing, bedding, toy, the mite killing of living space, sterilization.
It is prepared as described above step and obtains print chinaberry mite killing, fungicide, print chinaberry mite killing, fungicide are subjected to killing effect experiment,
It is dust mite for examination acarid, takes the filter paper for being coated with various concentration killing acarus and bacteria agent sample solution, be respectively placed in culture dish, and to
Be put into a certain number of acarids in culture dish, cultivated in constant incubator at 25 DEG C, and in for 24 hours, 48h, 72h observe and record mite
The worm death rate, all experiment process are in triplicate.Experimental result is as follows:
As shown in Table 1, with the growth for the increase test period that dosage is added, the acarid death rate is continuously improved, miticidal effect
It becomes better and better.Therefore the it is found that specific good using effect of killing acarus and bacteria agent of the method for the present invention preparation.
The invention has the benefit that
1, life habit of the present invention for acarid, the feature nontoxic and without secondary pollution using natural plant extracts,
While realizing to the killing of human body acarid, the influence to human health is reduced.
2, used plant extracts have the characteristics that anti-inflammation and sterilization, after without skin allergy, rest on skin table
The regeneration of face acceptable pre- anti-mite while killing acarid.
3, the present invention can solve existing Chemical acaricide secondary pollution problems, be a kind of based on plant extracts preparation
Health, the innovative approach of environmental protection, efficient killing acarus and bacteria agent.
Specific embodiment
Below in conjunction with specific embodiment the present invention is described in detail content.It should be noted that being described in following embodiments
Technical characteristic or the combination of technical characteristic be not construed as isolated, they can be combined with each other to reaching more
Good technical effect.
Embodiment 1
A method of killing acarus and bacteria agent is prepared by neem kernel, is included the following steps:
Step 1: neem kernel is cleaned, low temperature drying, crushed 16 meshes；
Step 2: the neem kernel powder of crushing is packed into hollow glass column, is extracted 3 times with HPLC grades of n-hexanes, 45 DEG C of backspins
Turn evaporative removal n-hexane, obtains substance a；
Step 3: by substance a that the step 2 obtains with there is pump to remove residual solvent, obtain containing oil soluble insecticidal activity at
The extract b divided；
Step 4: the extract b for taking the step 3 to obtain is added stabilizer and is compounded, and obtains mite killing, fungicide, stabilizer
Including citric acid, vitamin E and arabo-ascorbic acid.
The ingredient of finally obtained mite killing, fungicide are as follows: 5% citric acid, 5% vitamin E, 5% arabo-ascorbic acid and 85% print
Chinaberry extract.
Embodiment 2
A method of killing acarus and bacteria agent is prepared by neem kernel, is included the following steps:
Step 1: neem kernel is cleaned, low temperature drying, crushed 16 meshes；
Step 2: the neem kernel powder of crushing is packed into hollow glass column, is extracted 3 times with HPLC grades of n-hexanes, 35 DEG C of backspins
Turn evaporative removal n-hexane, obtains substance a；
Step 3: by substance a that the step 2 obtains with there is pump to remove residual solvent, obtain containing oil soluble insecticidal activity at
The extract b divided；
Step 4: the extract b for taking the step 3 to obtain is added stabilizer and is compounded, and obtains mite killing, fungicide, stabilizer
Including citric acid, vitamin E and arabo-ascorbic acid.
The ingredient of finally obtained mite killing, fungicide are as follows: 5% citric acid, 5% vitamin E, 5% arabo-ascorbic acid and 85% print
Chinaberry extract.
Embodiment 3
A method of killing acarus and bacteria agent is prepared by neem kernel, is included the following steps:
Step 1: neem kernel is cleaned, low temperature drying, crushed 16 meshes；
Step 2: the neem kernel powder of crushing is packed into hollow glass column, is extracted 3 times with HPLC grades of n-hexanes, 40 DEG C of backspins
Turn evaporative removal n-hexane, obtains substance a；
Step 3: by substance a that the step 2 obtains with there is pump to remove residual solvent, obtain containing oil soluble insecticidal activity at
The extract b divided；
Step 4: the extract b for taking the step 3 to obtain is added stabilizer and is compounded, and obtains mite killing, fungicide, stabilizer
Including citric acid, vitamin E and arabo-ascorbic acid.
The ingredient of finally obtained mite killing, fungicide are as follows: 5% citric acid, 5% vitamin E, 5% arabo-ascorbic acid and 85% print
Chinaberry extract.
The print chinaberry mite killing that is prepared in aforementioned manners, the purposes of fungicide be in mass ratio 1% ~ 3% be added to washing powder,
In hand cleanser, humans and animals body surface, clothing, bedding, toy, the mite killing of living space, sterilization can be applied to.
The present invention is directed to the life habit of acarid, the spy nontoxic and without secondary pollution using natural plant extracts
Point reduces the influence to human health while realizing to the killing of human body acarid；Used plant extracts has anti-inflammatory
Sterilization, after without skin allergy the features such as, resting on skin surface, acceptable pre- anti-mite is again while killing acarid
It is raw；The present invention can solve existing Chemical acaricide secondary pollution problems, be a kind of based on plant extracts preparation health, ring
It protects, the innovative approach of efficient killing acarus and bacteria agent.
Although having been presented for some embodiments of the present invention herein, it will be appreciated by those of skill in the art that
Without departing from the spirit of the invention, the embodiments herein can be changed.Above-described embodiment is only exemplary, no
It should be using the embodiments herein as the restriction of interest field of the present invention.
Claims (9)
1. a kind of print chinaberry mite killing, fungicide, which is characterized in that containing neem extract and stabilizer, the stabilizer includes lemon
Lemon acid, vitamin E, arabo-ascorbic acid.
2. a kind of print chinaberry mite killing as described in claim 1, fungicide, which is characterized in that the mite killing, bacteriocide formula are as follows:
5% citric acid, 5% vitamin E, 5% arabo-ascorbic acid and 85% neem extract.
3. a kind of print chinaberry mite killing as described in claim 1, fungicide, which is characterized in that the neem extract is print chinaberry
The mixture of oil and germicide-acaricide active constituent.
4. a kind of print chinaberry fungicide as described in claim 1, which is characterized in that the dosage form of the print chinaberry fungicide can be cream
It is oil, microemulsion, arbitrary a kind of in aqueous emulsion.
5. a kind of prepare print chinaberry mite killing, the method for fungicide as described in claim 1, which comprises the steps of:
Step 1: neem kernel is cleaned, low temperature drying, crushed 16 meshes；
Step 2: the neem kernel powder of crushing being packed into hollow glass column, is extracted with n-hexane, rotary evaporation removal just oneself
Alkane obtains substance a；
Step 3: by substance a that the step 2 obtains with there is pump to remove residual solvent, obtain containing oil soluble insecticidal activity at
The extract b divided；
Step 4: the extract b that the step 3 obtains is compounded, mite killing, fungicide are obtained.
6. preparation print chinaberry mite killing, the method for fungicide as claimed in claim 5, which is characterized in that in the step 2 just
Hexane is HPLC grades, is extracted 3 times, and rotating evaporation temperature is 35 ~ 45 DEG C.
7. preparation print chinaberry mite killing, the method for fungicide as claimed in claim 5, which is characterized in that answering in the step 4
With for be added stabilizer: citric acid, vitamin E and arabo-ascorbic acid.
8. preparation print chinaberry mite killing, the method for fungicide as claimed in claim 5, which is characterized in that the step 4 obtained
The ingredient of mite killing, fungicide are as follows: 5% citric acid, 5% vitamin E, 5% arabo-ascorbic acid and 85% neem extract.
9. a kind of print chinaberry mite killing, the purposes of fungicide as described in claim 1, which is characterized in that in mass ratio 1% ~ 3% addition
Into washing powder, hand cleanser.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910144361.6A CN109805037A (en) | 2019-02-27 | 2019-02-27 | A kind of print chinaberry mite killing, fungicide and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910144361.6A CN109805037A (en) | 2019-02-27 | 2019-02-27 | A kind of print chinaberry mite killing, fungicide and its preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109805037A true CN109805037A (en) | 2019-05-28 |
Family
ID=66607497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910144361.6A Pending CN109805037A (en) | 2019-02-27 | 2019-02-27 | A kind of print chinaberry mite killing, fungicide and its preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109805037A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6060075A (en) * | 1997-08-27 | 2000-05-09 | Vittal Mallya Scientific Research Foundation | Check mite composition and a process for preparing the same |
| CN1368046A (en) * | 2002-01-30 | 2002-09-11 | 云南中科生物产业有限公司 | Nim cosmetics series based on active component of nim for daily use and its preparing process |
| CN101537044A (en) * | 2009-04-24 | 2009-09-23 | 四川鼎尖动物药业有限责任公司 | Neem oil microemulsion and application thereof |
| US20090263517A1 (en) * | 2005-06-08 | 2009-10-22 | Terra Nostra Produkte Mit Naturextrakten Gmbh | Method for producing margosa extract |
| US20100092529A1 (en) * | 2001-06-22 | 2010-04-15 | Nathalie Chetboun | Method for Acaricidal and Microbicidal Treatment of Textile Materials |
| CN106491399A (en) * | 2016-11-07 | 2017-03-15 | 成都绿金生物科技有限责任公司 | A kind of removing lice drives demodicid mite spray and preparation method thereof |
-
2019
- 2019-02-27 CN CN201910144361.6A patent/CN109805037A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6060075A (en) * | 1997-08-27 | 2000-05-09 | Vittal Mallya Scientific Research Foundation | Check mite composition and a process for preparing the same |
| US20100092529A1 (en) * | 2001-06-22 | 2010-04-15 | Nathalie Chetboun | Method for Acaricidal and Microbicidal Treatment of Textile Materials |
| CN1368046A (en) * | 2002-01-30 | 2002-09-11 | 云南中科生物产业有限公司 | Nim cosmetics series based on active component of nim for daily use and its preparing process |
| US20090263517A1 (en) * | 2005-06-08 | 2009-10-22 | Terra Nostra Produkte Mit Naturextrakten Gmbh | Method for producing margosa extract |
| CN101537044A (en) * | 2009-04-24 | 2009-09-23 | 四川鼎尖动物药业有限责任公司 | Neem oil microemulsion and application thereof |
| CN106491399A (en) * | 2016-11-07 | 2017-03-15 | 成都绿金生物科技有限责任公司 | A kind of removing lice drives demodicid mite spray and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| JITKA STARA´ ET,AL: "The toxicity of selected acaricides against five stored product mites under laboratory assay", 《JOURNAL OF PEST ENCE》 * |
| 吕晓华等: "《食品安全与健康》", 31 July 2018, 中国医药科技出版社 * |
| 张雷红等: "《天然药物化学 第3版》", 31 January 2017, 中国医药科技出版社 * |
| 邵颖等: "《食品化学》", 31 January 2008, 中国轻工业出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101904406B1 (en) | A composition for controlling Dermanyssus gallinae and the method of controlling Dermanyssus gallinae by using the same | |
| KR20180069278A (en) | Insect repellent composition and preparing method thereof | |
| KR101694707B1 (en) | Deodorant composition comprising the extract of Abeliophyllum distichum Nakai distichum | |
| JP2010512381A (en) | Herbal preparations for wound treatment | |
| KR20190080011A (en) | Composition for mosquito repellent containing naturally extracting components | |
| CN110637839A (en) | Jasmine flower mosquito repellent with nerve calming and sleep aiding effects and preparation method thereof | |
| CN109260054A (en) | A kind of plant mosquito-repellent antipruritic cream and preparation method thereof | |
| CN107873701A (en) | A kind of aerosol for expelling parasite, sterilizing and mite killing and preparation method thereof | |
| KR102292707B1 (en) | Antiviral composition comprising natural substance-derived substance and acidic hypochlorous acid | |
| KR20150029881A (en) | Mosquito repellent compositions | |
| KR102213514B1 (en) | Natural composition for inhibiting corona virus activity | |
| CN104621192A (en) | Natural plant anti-mite insert-killing fragrant agent | |
| KR101898060B1 (en) | Natural aroma essential oil water soluble composition for humidifier disinfectant and the method of manufaturing the same | |
| KR101416984B1 (en) | A mosquito-repellent, and method for preparing thereof | |
| EP3876719A1 (en) | Insect repellent composition | |
| KR20200137703A (en) | A natural composition for mosquito repellent | |
| CN105708763A (en) | Artemisia argyi Levl extract-containing floral water and preparation method thereof | |
| KR20110045440A (en) | Mosquito repellent compositions | |
| CN109805037A (en) | A kind of print chinaberry mite killing, fungicide and its preparation method and application | |
| KR101761471B1 (en) | Vegetable oil mixture with excellent anti-insect and deodorization | |
| CN111481567B (en) | Compound ozone oil and preparation method and application thereof | |
| KR20160009331A (en) | Natural cosmetic compositions for outdoor activity | |
| CN107410384A (en) | A kind of plants herb mosquito-repellent incense and preparation method thereof | |
| CN106719881A (en) | A kind of mosquito repellent liquid and preparation method thereof for being based on four taste Chinese herbal medicines | |
| KR20130026742A (en) | The preparations method of mosquito and harmful insect eradication such as a natural insecticide extracted from the ginkgo tree ingredient |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: 571101 No. 4, Longhua, Haikou District, Hainan, Xueyuan Road Applicant after: Chinese Academy of Tropical Agricultural Sciences Environment and Plant Protection Institute Address before: 571700 Baodao new village, Danzhou City, Hainan Province Applicant before: Chinese Academy of Tropical Agricultural Sciences Environment and Plant Protection Institute |
|
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wu Lin Inventor after: Liu Beibei Inventor after: Peng Lixu Inventor after: Chen Xin Inventor after: Pan Pan Inventor after: Fu Yiqing Inventor before: Liu Beibei Inventor before: Wu Lin Inventor before: Peng Lixu Inventor before: Chen Xin Inventor before: Pan Pan Inventor before: Fu Niqing |
|
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190528 |