CN109718282A - It is a kind of to treat diabetes compound Chinese herb capsule and preparation method - Google Patents

It is a kind of to treat diabetes compound Chinese herb capsule and preparation method Download PDF

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Publication number
CN109718282A
CN109718282A CN201910188069.4A CN201910188069A CN109718282A CN 109718282 A CN109718282 A CN 109718282A CN 201910188069 A CN201910188069 A CN 201910188069A CN 109718282 A CN109718282 A CN 109718282A
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grams
diabetes
blood
medicinal extract
years
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李国庆
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Guizhou Grams Acon Pharmaceutical Development Co Ltd
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Guizhou Grams Acon Pharmaceutical Development Co Ltd
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Abstract

It is a kind of to treat diabetes compound Chinese herb capsule and preparation method, it matches by weight as follows: 20-35 grams of hairyvein agrimony, 30-45 grams of lotus core, 20-35 grams of bombyx batryticatus, 25-40 grams of Schisandra chinensis, 20-25 grams of pheretima, 20-35 grams of subprostrate sophora.The present invention can restore insulin with respect to hyposecretion, or insulin blood glucose element is inadequately caused by hypersecretion with the function of carbohydrate metabolism disturbance, have effects that Yin nourishing and lung moistening, relieving restlessness and restlessness, reinforcing stomach reg fluid, nourishing liver and kidney, nourishing yin to moisten dryness, QI invigorating heat-clearing, promote the production of body fluid to quench thirst, phlegm reduction of blood circulation promoting, to diabetes B with dosage is small, quick, healing time is short, curative effect is high, Small side effects, lifelong medication is not required to after healing, glucostasis does not rebound, to reach treating both manifestation and root cause of disease, fundamentally cure diabetes, efficient 95%, 84% or more cure rate.

Description

It is a kind of to treat diabetes compound Chinese herb capsule and preparation method
Technical field
Diabetes compound Chinese herb capsule and preparation method are treated the present invention relates to a kind of.
Background technique
Existing treatment hypoglycemic drug mainly has: sulfonylureas, melbine class, insulin sensitizer, glucuroide suppression Preparation, thiazolidine diketone derivative, subcutaneous insulin injections, these medication effects are bad, and side effect is big and adverse reaction More medical problems.
Summary of the invention
The present invention be it is bad in order to solve existing hypoglycemic drug therapeutic effect, toxic side effect is big and adverse reaction more than doctor Medicine problem.
In order to solve the above-mentioned technical problem, the present invention adopts the following technical scheme:
It is a kind of to treat diabetes compound Chinese herb capsule, it matches by weight as follows:
20-35 grams of hairyvein agrimony, 30-45 grams of lotus core, 20-35 grams of bombyx batryticatus, 25-40 grams of Schisandra chinensis, 20-25 grams of pheretima, mountain beans 20-35 grams of root.
A kind of preparation method for treating diabetes compound Chinese herb capsule, steps are as follows:
(1) by 20-35 grams of hairyvein agrimony, 30-45 grams of lotus core, 20-35 grams of bombyx batryticatus, 25-40 grams of Schisandra chinensis, pheretima 20-25 Gram, 20-35 grams of subprostrate sophora, amount to six medicaments mixing, after being crushed to 5 mesh fineness, boiled and mentioned with Chinese medicine extraction machine, boil and mention plus water Amount is 4 times of six medicaments total weight, adds 3 times that 40% ethyl alcohol is six medicaments total weight, boils and mention after impregnating 12 hours, Boil temperature raising degree and be maintained at 75-85 DEG C, boil mention the time be 4 hours, filter and remove residue obtains medical fluid;
(2) medical fluid is concentrated into the medicinal extract of relative density 0.9-1.1 in 75-85 DEG C of temperature, drops to 30 to medicinal extract temperature DEG C when be added 95% ethyl alcohol, amount of alcohol added is 6 times of medicinal extract total amount, stir evenly standing after 18 hours medicinal extract supernatant;
(3) medicinal extract supernatant ethanol recovery device is recycled into ethyl alcohol, obtains semi-finished product;
(4) semi-finished product are dry under 95 DEG C of constant temperatures, the semi-finished product water tariff collection after drying uses micro mist between 3-5% Machine is crushed to 800-1000 mesh fine powders;
(5) semi-finished product are dry under 95 DEG C of constant temperatures, the semi-finished product water tariff collection after drying uses micro mist between 3-5% Machine is crushed to 800-1000 mesh fine powders;
(6) 95% ethyl alcohol is added with fine powder total weight, amount of alcohol added is fine powder total amount 10%, mixes granulation thoroughly, crosses 20 mesh hole sizer systems Dry under 95 DEG C of constant temperatures after granulating, the water tariff collection after drying is between 3-5%, physical sterilization after drying, with 0# glue Capsule filling, every nt wt net weight are 0.38 gram, and nt wt net weight error must not exceed ± 3%.
Beneficial effect by adopting the above technical scheme is:
The present invention can restore insulin with respect to caused by hyposecretion or insulin blood glucose element inadequately hypersecretion with sugar The function of metabolic disorder has Yin nourishing and lung moistening, relieving restlessness and restlessness, reinforcing stomach reg fluid, nourishing liver and kidney, nourishing yin to moisten dryness, QI invigorating heat-clearing, promotes the production of body fluid Quench the thirst, phlegm reduction of blood circulation promoting the effect of, to diabetes B have dosage is small, quick, healing time is short, curative effect is high, toxic side effect It is small, lifelong medication is not required to after healing, glucostasis does not rebound, to reach treating both manifestation and root cause of disease, fundamentally cures diabetes, effectively Rate 95%, 84% or more cure rate.
Specific embodiment
Embodiment 1
It is a kind of to treat diabetes compound Chinese herb capsule, it matches by weight as follows:
30 grams of hairyvein agrimony, 40 grams of lotus core, 33 grams of bombyx batryticatus, 37 grams of Schisandra chinensis, 24 grams of pheretima, 32 grams of subprostrate sophora.
Embodiment 2
It is a kind of to treat diabetes compound Chinese herb capsule, it matches by weight as follows:
28 grams of hairyvein agrimony, 35 grams of lotus core, 30 grams of bombyx batryticatus, 35 grams of Schisandra chinensis, 22 grams of pheretima, 30 grams of subprostrate sophora.
Embodiment 3
It is a kind of to treat diabetes compound Chinese herb capsule, it matches by weight as follows:
25 grams of hairyvein agrimony, 30 grams of lotus core, 29 grams of bombyx batryticatus, 33 grams of Schisandra chinensis, 20 grams of pheretima, 25 grams of subprostrate sophora.
Embodiment 4
It is a kind of to treat diabetes compound Chinese herb capsule, it matches by weight as follows:
23 grams of hairyvein agrimony, 26 grams of lotus core, 25 grams of bombyx batryticatus, 30 grams of Schisandra chinensis, 18 grams of pheretima, 22 grams of subprostrate sophora.
Embodiment 5
It is a kind of to treat diabetes compound Chinese herb capsule, it matches by weight as follows:
20 grams of hairyvein agrimony, 23 grams of lotus core, 20 grams of bombyx batryticatus, 25 grams of Schisandra chinensis, 15 grams of pheretima, 17 grams of subprostrate sophora.
It is according to dosage taken by the finished product that above-mentioned formula and processing technology process produces, takes a kind of treat in diabetes compound Herbal medicine capsule has effects that improve mitigation hypoglycemic rapidly, declines blood glucose steadily, restore insulin normal secretions, sample is simultaneous Control, more after do not rebound, be not required to lifelong medication, dose is 3 times a day, two every time, early, middle and late bfore meals, 30 days for one treat Journey, 5-10 courses for the treatment of are cured, and glucostasis does not return bullet.
A kind of preparation method for treating diabetes compound Chinese herb capsule, steps are as follows:
(1) by 34 grams of hairyvein agrimony, 35 grams of lotus core, 25 grams of bombyx batryticatus, 38 grams of Schisandra chinensis, 22 grams of pheretima, 30 grams of subprostrate sophora, amount to Six-element Drug mixing, after being crushed to 5 mesh fineness, is boiled with Chinese medicine extraction machine and is mentioned, and boils 4 times for mentioning amount of water as six medicaments total weight, then 3 times that 40% ethyl alcohol is six medicaments total weight are added, boils and mentions after impregnating 12 hours, boil temperature raising degree and be maintained at 75-85 DEG C, boil and mention Time is 4 hours, and filter and remove residue obtains medical fluid;
(3) medical fluid is concentrated into the medicinal extract of relative density 0.9-1.1 in 75-85 DEG C of temperature, drops to 30 to medicinal extract temperature DEG C when be added 95% ethyl alcohol, amount of alcohol added is 6 times of medicinal extract total amount, stir evenly standing after 18 hours medicinal extract supernatant;
(4) medicinal extract supernatant ethanol recovery device is recycled into ethyl alcohol, obtains semi-finished product;
(5) semi-finished product are dry under 95 DEG C of constant temperatures, the semi-finished product water tariff collection after drying uses micro mist between 3-5% Machine is crushed to 800-1000 mesh fine powders;
(6) 95% ethyl alcohol is added with fine powder total weight, amount of alcohol added is fine powder total amount 10%, mixes granulation thoroughly, crosses 20 mesh hole sizer systems Dry under 95 DEG C of constant temperatures after granulating, the water tariff collection after drying is between 3-5%, physical sterilization after drying, with 0# glue Capsule filling, every nt wt net weight are 0.38 gram, and nt wt net weight error must not exceed ± 3%.
Typical case
Example 1: Hu, female, 65 years old, diabetes were suffered from 10 years in Zunyi City, Guizhou Province Honghuagang District, took melbine, six drugs containing rehmanniae Ball, blood glucose empty stomach 12.1, postprandial 2 hours 17.5-18.7 took this product one month in December, 2014, at period 10 days one month Inside subtract melbine 30%, second subtracts 60% in 10 days, and third 10 days 90%, sugared empty stomach 8.7, postprandial 11.1 of having a blood test, substantially surely It is fixed, then continuously take 4 months while tracking sugar of having a blood test, empty stomach 7.2, postprandial 10.1, checks blood glucose after consolidating 2 months before the meal 7.0-10.5 amounts to treatment 9 months, is discontinued 3 years and has no blood glucose rise.
Example 2: what so-and-so, male, 69 years old, Guiyang City, Guizhou Province Yunyan District diabetes 12 years, took melbine for a long time, on an empty stomach Blood glucose 9.1, postprandial 15.7, in March, 2016 takes this product, and it takes and subtracts melbine 30% the previous moon, fasting blood-glucose 8.7, after the meal 14.9, it is slightly decreased, second month subtracts melbine 60%, fasting blood-glucose 8.1, and postprandial 13.9, third month subtracts melbine 100%, fasting blood-glucose 8.0, postprandial blood sugar 12.0, blood glucose decline continuously takes 5 months follow-up investigations blood glucose simultaneously, and sky takes 7.0, 10-11.1 after upper, consolidates 3 months, amounts to 11 months and is discontinued 2 years so far, does not find that blood glucose has exception.
Example 3: Mr. Li, female 51 years old, suffer from diabetes 3 years, because fat, cholesterol is high, oily three rouge of glycosides is high, high blood pressure, do not take With any antidiabetic drug, fasting blood-glucose 9.5, postprandial blood sugar in August, 17.1,2016 takes this product, checks blood glucose on an empty stomach after 15 days 8.6, postprandial 14.1 are slightly decreased, and take fasting blood-glucose sugar 7.1 after two months, and postprandial blood sugar 12.0 is consolidated 3 months, amount to 5 Month, it on an empty stomach with postprandial blood sugar normal range (NR), is discontinued the time more than 2 years, blood glucose normally has no rising.
Example 4: Zhang, female, 65 years old, Wudang District, Guiyang City, Guizhou Province diabetes 7 years, was not eaten hypoglycemic agent, is taken always Liuwei Dihuang Wan, fasting blood-glucose 8.7, postprandial blood sugar in September, 15.0,2015 take this product, and blood sugar recovery is normal within 3 months.
Example 5: thanking so-and-so, and male, 47 years old, melbine diabetes 5 years, was taken 4 years in Zunyi City, Guizhou Province Honghuagang District, empty Abdomen blood glucose 7.9, postprandial blood sugar: 15.0, glycemic control effect is undesirable, and in September, 2016 takes this product, and it is double to subtract diformazan the previous moon After guanidine 50%, fasting blood-glucose 7.9, postprandial blood sugar 13.1, blood glucose is declined, and second month no longer takes melbine, blood glucose with Track inspection, empty stomach 7.4, postprandial 12.1 after treatment 4 months, amount to 6 months, and blood glucose empty stomach 7.1, postprandial 11.1 is close normal, It is discontinued 08 months 2 years, blood glucose is postprandial in range of normal value, no abnormality seen on an empty stomach.
Example 6: Chen, female, 71 years old, diabetes were suffered from 6 years in Zunyi City, Guizhou Province Honghuagang District, did not took any antidiabetic drug Object, fasting blood-glucose 8.0, postprandial 2 hours blood glucose take this product in January, 14.1,2017, the first two blood glucose follow-up investigations on an empty stomach 7.4, Postprandial 2 hours 12.0, consolidate 5 months, it is total to take 7 months, it is discontinued eight months 1 year so far, blood glucose no abnormality seen.
Example 7: Huang, male, 61 years old, Guizhou Province, the town Dong Huang, Xishui County suffered from hypertension 8 years, takes Niuhuang Jiangya piece 5 years, Sky takes blood glucose 8.7, and postprandial blood sugar 15.7, frequent headache, heart season is uncomfortable in chest, has a sleepless night, and takes this product in May, 2014 and withdraws the fresh poison of cow-bezoar Piece tracks sugar of having a blood test in 45 days, looks within 15 days sugar the 7.5, postprandial 13.0, the 45th day and keeps normal range (NR) within postprandial 2 hours on an empty stomach, consolidates It is discontinued after taking 5 months, it is total to take 6.5 months blood glucose empty stomaches so far, it is maintained at normal range (NR), no abnormality seen after the meal.
Example 8: Yuan so-and-so, female, 54 years old, Guizhou Province, the town Dong Huang, Xishui County suffered from diabetes 3 years, does not take any antidiabetic drug, blood Sugared empty stomach 9.1, meal 15.3 take this product one month sugar of having a blood test, empty stomach 7.5, postprandial 12.0, and follow-up investigations in 4 months are taken in consolidation Sky clothes, are maintained at normal range (NR) in postprandial two hours, amount to and are discontinued the 1 year and a half time so far after taking 5 months, check blood glucose 7.2- 11.8, still category normal range (NR).
Example 9: Mr. Luo, male, 65 years old, Liuwei Dihuang Wan diabetes 6 years, was taken 25 days, blood in Guizhou Province, the town Dong Huang, Xishui County Sugar empty stomach 9.0 before taking drops to 7.5, postprandial 16.7 and drops to 12.5, total to take 5 months, and blood glucose is postprandial on an empty stomach to be restored to just Often, it is discontinued 2 years half and tracks sugar of having a blood test, be maintained at normal range (NR), no abnormality seen.
Example 10: Chen, female, 60 years old, Guizhou Province, the town Dong Huang, Xishui County diabetes 3 years, did not ate any antidiabetic drug, usually Eat that dry balsam pear is soaked to be drunk, fasting blood-glucose 8.0, postprandial blood sugar takes this product 45 days in March, 13.0,2017, and blood sugar recovery is normal, consolidates It is discontinued admittedly taking 3 months, 2 annual tests so far are had a blood test sugared no abnormality seen.
Example 11: Mr. Li, female, 53 years old, Guizhou Province, the town Dong Huang, Xishui County, diabetes 2 years, blood glucose empty stomach 8.0, postprandial two is small When 13.0, do not take antidiabetic drug, take this product one month in April, 2018, empty stomach postprandial blood sugar restores normal, and consolidation takes 3 The moon is discontinued, and nearly follow-up investigations in 1 year are maintained at normal range (NR).
Example 12: ten thousand so-and-so, female, 48 years old, melbine diabetes 5 years, was eaten 3 years in Guizhou Province, the town Dong Huang, Xishui County, and blood glucose is empty Abdomen 7.8, postprandial 12.1, it takes this product in December, 2017 and directly withdraws 30 days sugar of having a blood test of melbine and be down to normal range (NR), consolidate It takes 3 months and is discontinued, have no blood glucose rise within 3 months 1 year so far.
Example 13: the Qin so-and-so, female, 61 years old, melbine diabetes 6 years, was eaten 5 years, fasting blood in Guizhou Province, the town Dong Huang, Xishui County Sugar 8.9, postprandial blood sugar 16.0, control hypoglycemic effect is undesirable, takes this product in January, 2018 and stops melbine 60 days, and blood glucose is empty Abdomen restores normally after the meal, and consolidation takes 5 months and is discontinued, and has no pathoglycemia within 1 year so far.
Example 14: Mr. Wang, female, 57 years old, Guizhou Province, the town Dong Huang, Xishui County diabetes 4 years, did not took any antidiabetic drug, empty Abdomen blood glucose 8.0, postprandial blood sugar in September, 13.0,2016 take this product 60 days, and blood sugar recovery is taken 3 months in normal range (NR), consolidation It is discontinued, tracks sugar of having a blood test within 2 years so far, be maintained at normal range (NR).
Example 15: Zhao so-and-so, male, 52 years old, Guizhou Province, the town Dong Huang, Xishui County, diabetes 2 years, fasting blood-glucose 7.5, postprandial blood sugar In January, 13.0,2018 takes this product 60 days, and blood sugar recovery is normal, and consolidation is taken to be discontinued within 3 months 1 year and be checked, has no that blood glucose is different Often.
Example 16: swimming so-and-so, male, and 49 years old, Zunyi City, Guizhou Province Honghuagang District, diabetes 3 years, fasting blood-glucose 7.9, postprandial blood Sugared in November, 13.0,2017 takes this product 60 days, looks into that blood sugar recovery is normal, and consolidation takes 3 months and is discontinued, nearly 2 years sugar of having a blood test It is maintained at normal range (NR).
Example 17: Liu, male, 57 years old, melbine diabetes 6 years, was taken 5 years, blood glucose in Guizhou Province, the town Dong Huang, Xishui County 8.5, postprandial blood sugar 14.7, fluctuation is very big up and down, takes in July, 2016 and stops melbine between this product 45 days, tracks sugar of having a blood test Restore within 25 days close to fasting blood-glucose 7.0 normally, is looked within 45 days, postprandial 2 hours 11.0, consolidation took 3 months and is discontinued, so far more than 2 years Have no pathoglycemia.
Example 18: Nie so-and-so, male, 59 years old, Zunyi City, Guizhou Province safflower hilllock diabetes 2 years, did not took antidiabetic drug, in January, 2018 60 days sugar of having a blood test of this product is taken, restores normal, consolidation takes 2 months and is discontinued, and has no pathoglycemia within 1 year so far.
Example 19: Zhao so-and-so, male, 68 years old, Zunyi City, Guizhou Province Honghuagang District, diabetes 6 years, take for a long time melbine, Fasting blood-glucose 7.8, postprandial blood sugar in August, 13.1,2016 take this product and stop Western medicine, blood sugar recovery normal value in 45 days, consolidate clothes It was discontinued with 4 months, tracks sugared no abnormality seen of having a blood test.
Example 20: week so-and-so, male, 73 years old, melbine diabetes 15 years, was taken in Zunyi City, Guizhou Province Honghuagang District, 2014 It takes this product 60 days in year December, 50%-100% is inside divided to subtract melbine, blood glucose 8.0 drops to 7.0 before taking this product, consolidates clothes It was discontinued with 6 months, 4 years so far follow-up investigations blood glucose no abnormality seens.

Claims (2)

1. a kind of treat diabetes compound Chinese herb capsule, it is characterised in that: match by weight as follows:
20-35 grams of hairyvein agrimony, 30-45 grams of lotus core, 20-35 grams of bombyx batryticatus, 25-40 grams of Schisandra chinensis, 20-25 grams of pheretima, mountain beans 20-35 grams of root.
2. a kind of preparation method for treating diabetes compound Chinese herb capsule, it is characterised in that: steps are as follows:
(1) by 20-35 grams of hairyvein agrimony, 30-45 grams of lotus core, 20-35 grams of bombyx batryticatus, 25-40 grams of Schisandra chinensis, pheretima 20-25 Gram, 20-35 grams of subprostrate sophora, amount to six medicaments mixing, after being crushed to 5 mesh fineness, boiled and mentioned with Chinese medicine extraction machine, boil and mention plus water Amount is 4 times of six medicaments total weight, adds 3 times that 40% ethyl alcohol is six medicaments total weight, boils and mention after impregnating 12 hours, Boil temperature raising degree and be maintained at 75-85 DEG C, boil mention the time be 4 hours, filter and remove residue obtains medical fluid;
(2) medical fluid is concentrated into the medicinal extract of relative density 0.9-1.1 in 75-85 DEG C of temperature, drops to 30 to medicinal extract temperature DEG C when be added 95% ethyl alcohol, amount of alcohol added is 6 times of medicinal extract total amount, stir evenly standing after 18 hours medicinal extract supernatant;
(3) medicinal extract supernatant ethanol recovery device is recycled into ethyl alcohol, obtains semi-finished product;
(4) semi-finished product are dry under 95 DEG C of constant temperatures, the semi-finished product water tariff collection after drying uses micro mist between 3-5% Machine is crushed to 800-1000 mesh fine powders;
(5) 10% ethyl alcohol is added with fine powder total weight and mixes granulation thoroughly, after grain is made in 20 mesh hole sizers excessively, done under 95 DEG C of constant temperatures Dry, the water tariff collection after drying between 3-5%, filled with 0# capsule by physical sterilization after drying, and every nt wt net weight is 0.38 Gram, nt wt net weight error must not exceed ± 3%.
CN201910188069.4A 2019-03-13 2019-03-13 It is a kind of to treat diabetes compound Chinese herb capsule and preparation method Pending CN109718282A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112022961A (en) * 2020-10-28 2020-12-04 贵州克艾康医药开发有限公司 Compound Chinese herbal medicine capsule for treating chronic nephritis and preparation method thereof
CN112138113A (en) * 2020-10-28 2020-12-29 贵州克艾康医药开发有限公司 Compound Chinese herbal medicine capsule for treating and killing cryptococcus neoformans and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1415332A (en) * 2002-11-28 2003-05-07 王连俊 Capsule for curing diabetes and its preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1415332A (en) * 2002-11-28 2003-05-07 王连俊 Capsule for curing diabetes and its preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马凤友等: "糖尿病临证举隅", 《糖尿病临证举隅 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112022961A (en) * 2020-10-28 2020-12-04 贵州克艾康医药开发有限公司 Compound Chinese herbal medicine capsule for treating chronic nephritis and preparation method thereof
CN112138113A (en) * 2020-10-28 2020-12-29 贵州克艾康医药开发有限公司 Compound Chinese herbal medicine capsule for treating and killing cryptococcus neoformans and preparation method thereof

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