CN109718167A - A kind of hand lotion and preparation method thereof with maintenance and moisture-keeping efficacy - Google Patents
A kind of hand lotion and preparation method thereof with maintenance and moisture-keeping efficacy Download PDFInfo
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Abstract
The present invention relates to cosmetic technical field more particularly to a kind of hand lotions and preparation method thereof with maintenance and moisture-keeping efficacy.The invention discloses a kind of hand lotion with maintenance and moisture-keeping efficacy, transdermal oligopeptides -1 in the hand lotion can promote the Proliferation, Differentiation of Skin Cell, improve skin resistance, so as to improve skin quality, urea has good wetting and moisture-keeping function, but it easily decomposes, lemon triethylenetetraminehexaacetic acid rouge can prevent the decomposition of urea as the stabilizer of urea, improve the moisture-retaining capacity of hand lotion.By experimental data it is found that hand lotion moistening effect provided in an embodiment of the present invention is significant, persistence is good, and it is not significant to solve existing moisturizer moistening effect, unabiding problem.
Description
Technical field
The present invention relates to cosmetic technical field more particularly to a kind of hand lotions and its system with maintenance and moisture-keeping efficacy
Preparation Method.
Background technique
Skin is the organ that human body is directly contacted with the external world, is easy to be influenced by extraneous dry air, ultraviolet light, makes skin
Skin is damaged, dry water shortage.Skin water shortage, cytoplasm are reduced, and skin follows the string and reparative regeneration speed slows down, and can go out
The skin problems such as existing shrivelled, wrinkle.And after skin aging, stratum corneum barrier is weak, and such vicious circle leads to barrier reparation
Always it is in a backward condition.Therefore, moisturizing is the basis that cosmetics play other effects.
There are many existing moisturizer on the market, but moistening effect is not significant, not persistently.
Summary of the invention
The present invention provides a kind of hand lotion and preparation method thereof with maintenance and moisture-keeping efficacy, solves existing
Moisturizer moistening effect it is not significant, unabiding problem.
Its specific technical solution is as follows:
The present invention provides a kind of hand lotions, are made of the following components:
Glycerol, allantoin, carbomer, methyl esters, EDTA-2Na, Sodium Hyaluronate, five dimethione of ring, phytosterol
Rouge, 16/18 alcohol, propyl ester, 1-8 parts of 2-EHP, A165, monoglyceride, SIMULGEL EG, triethanolamine, transdermal oligopeptides -1, EUXYL
PE9010 preservative, SC-Glucan, centella asiatica extract, BSASM, urea and lemon triethylenetetraminehexaacetic acid rouge.
It should be noted that glycerol: INCI glycerine.
Allantoin: INCI Allantoins.
Carbomer: INCI polyacrylic acid.
Methyl esters: INCI methyl p-hydroxybenzoates.
EDTA-2Na:INCI disodium ethylene diamine tetraacetates.
Sodium Hyaluronate: hyaluronic acid is a kind of acid mucopolysaccharide, has special water retention, its hyalomitome molecule
The moisture that 500 times or more can be carried is the substance that moisture retention is best in presently found nature, be ideal natural moisture preserving because
Son, while being also good skin penetration enhancer, promotion nutrient absorption can be played by being used cooperatively with other nutritional ingredients
Effect.
Five dimethione of ring: belong to one kind of synthesis silicone oil.
Phytosterol rouge a: steroids of plant origin.
16/18 alcohol: INCI cetostearyl alcohols.
Propyl ester: INCI propylparabens.
2-EHP:INCI ethylhexyl palmitate.
A165:INCI PEG-100 stearates (and) stearine.
Monoglyceride: INCI dihydroxypropyl octadecane acid esters.
SIMULGEL EG:INCI title sodium acrylate/sodium acryloyldimethyl taurate copolymers.
Transdermal oligopeptides -1: merging recombinant human epidermal growth factor oligopeptides -1 of transdermal small peptide, will using recombinant DNA technology
The Novel clock that transdermal small peptide TD-1 (transdermal small peptide structure annular in shape, be made of 11 amino acid) is formed after connecting with oligopeptides -1
Skin growth factor is obtained by Bacillus coli expression and purifying.
EUXYL PE9010 preservative: INCI Phenoxyethanols (and) Sensiva SC50.
SC-Glucan:INCI beta glucans.
BSASM: being a kind of plant origin anti-sensitizer being made of various plants extract, such as rosemary, chamomile, tea
Tree, glycyrrhiza glabra, polygonum cuspidate, radix scutellariae and blood clam shell grass have multiple function for example anti-oxidant, releive, calm and immunomodulatory effect.
Urea: being medical grade urea used in the present invention.
Triethyl citrate: INCI 2- hydroxyls -1,2,3- tricarballylic acid's triethyl.
Preferably, by weight, glycerol 1-8 parts, 0.1-2 parts of allantoin, 1-2 parts of carbomer, methyl esters 0.05-0.25
Part, 0.01-0.08 parts of EDTA-2Na, 0.1-0.5 parts of Sodium Hyaluronate, 1-5 parts of five dimethione of ring, phytosterol rouge
0.5-1 parts, 0.1-3 parts of 16/18 alcohol, 0.01-0.1 parts of propyl ester, 1-8 parts of 2-EHP, 0.1-5 parts of A165,0.1-4 parts of monoglyceride,
0.5-2 parts of SIMULGEL EG, 1-2 parts of triethanolamine, -1 0.5-2 parts of transdermal oligopeptides, EUXYL PE9010 preservative 0.1-
0.5 part, 0.1-2 parts of SC-Glucan, 0.1-2 parts of centella asiatica extract, 0.1-3 parts of BSASM, 5-20 parts of urea, citric acid three
0.5-5 parts of second rouge.
In the present invention, 60~80 parts of deionized water.
Preferably, further includes: 0.01-0.08 parts of essence.Essence is preferably Ocean essence, and Ocean essence is a kind of artificial conjunction
At essence, in cosmetic applications promoted product fragrance, generate the feeling of pleasant.
Preferably, by weight, 2~6 parts of glycerol, 0.3~1 part of allantoin, 1~1.5 part of carbomer, methyl esters 0.15~
0.2 part, 0.05~0.08 part of EDTA-2Na, 0.2~0.4 part of Sodium Hyaluronate, 3~5 parts of five dimethione of ring, plant
0.8~1 part of sterol ester, 1~3 part of 16/18 alcohol, 0.05~0.1 part of propyl ester, 3~6 parts of 2-EHP, 3~5 parts of A165, monoglyceride 2
~4 parts, EG1~2 part SIMULGEL, 1~2 part of triethanolamine, -1 1~2 part of transdermal oligopeptides, EUXYL PE9010 preservative
0.2~0.5 part, 1~2 part of SC-Glucan, 1~2 part of centella asiatica extract, BSASM1~3 part, 10~15 parts of urea, lemon
2~5 parts of triethylenetetraminehexaacetic acid rouge.
Preferably, by weight, 6 parts of glycerol, 0.5 part of allantoin, 1 part of carbomer, 0.2 part of methyl esters, EDTA-2Na
0.05 part, 0.3 part of Sodium Hyaluronate, 3 parts of five dimethione of ring, 1 part of phytosterol rouge, 2 parts of 16/18 alcohol, propyl ester 0.1
Part, 5 parts of 2-EHP, 3 parts of A165,3 parts of monoglyceride, 1.2 parts of SIMULGEL EG, 1 part of triethanolamine, -1 2 part of transdermal oligopeptides,
0.4 part of EUXYL PE9010 preservative, 1 part of SC-Glucan, 2 parts of centella asiatica extract, 2 parts of BSASM, 12 parts of urea, lemon
3 parts of triethylenetetraminehexaacetic acid rouge.
The present invention also provides the preparation methods of above-mentioned hand lotion, comprising the following steps:
Step 1: after hyaluronic acid is diluted, carbomer is added, obtains the first product；
Step 2: glycerol, allantoin, methyl esters and EDTA-2Na are sequentially added in the first product of Xiang Suoshu carries out the first homogeneous,
Obtain the second product；
Step 3: sequentially added in the second product of Xiang Suoshu ring five dimethyl silicone polymer, phytosterol rouge, 16/18 alcohol,
Propyl ester, 2-EHP, A165 and monoglyceride mixing, obtain third product；
Step 4: SIMULGEL EG being added in Xiang Suoshu third product and carries out the second homogeneous, obtains the 4th product；
Step 5: being mixed triethanolamine is added in the 4th product, obtain the 5th product；
Step 6: after the 5th product is cooled to 44 DEG C~46 DEG C, sequentially adding transdermal widow in the 5th product of Xiang Suoshu
After peptide -1, EUXYL PE9010 preservative, SC-Glucan, centella asiatica extract, BSASM and triethyl citrate are mixed,
Urea is added, hand lotion is obtained.
Preferably, after addition carbomer described in step 1, before obtaining first product, further includes: be heated to 85 DEG C
~90 DEG C, preferably 85 DEG C keep the temperature 2h~2.5h, preferably 2h.
It in the present invention, is diluted described in step 1 specifically: Sodium Hyaluronate is added in pure water, stirs evenly and impregnates 2h
~3h, preferably 2h.It should be noted that peculiar smell is generated to avoid Sodium Hyaluronate from individually heating, Sodium Hyaluronate in step 1
Impregnate should use room temperature pure water.Pure hyaluronic acid sodium is white lightweight powder, can water swelling change after impregnating in pure water
For transparent colloid, stirs evenly in soaking process and can prevent Sodium Hyaluronate from agglomerating.Sodium Hyaluronate is 0.3 in the present invention
Part, pure water are 50 parts.
Preferably, the revolving speed of the first homogeneous described in step 2 is 10000~15000rpm, and the time of first homogeneous is
20min~30min, more preferably 20min.
In the present invention, after step 2 carries out first homogeneous, it is also necessary to keep the temperature 10min~15min, more preferably
10min。
In the present invention, the revolving speed of second homogeneous of step 4 is 15000~20000rpm, the time of the second homogeneous be 20min~
30min, preferably 20min.
Preferably, before the addition triethanolamine described in step 5, further includes: by the 4th product be cooled to 60 DEG C~
65 DEG C, more preferably 60 DEG C.
Mixing described in step 5 is mixed by stirring, and the rate of the stirring is 3000~3500rpm/min, described
The time of stirring is 15min~20min, more preferably 15min.
In the present invention, in step 6, cool down preferably to 45 DEG C；
It is added after lemon triethylenetetraminehexaacetic acid rouge, is added before urea, also need that essence is added.
In the preparation method of traditional hand lotion, since urea can be in the lotion of hand lotion under the action of no protective agent
It slowly decomposes, stability is poor, causes the fluctuation of its pH value larger, to make lotion phenomena such as thinning, layering occur, to product
Stability is particularly disadvantageous.In the present invention, urea is put into again after putting into lemon triethylenetetraminehexaacetic acid rouge at 44 DEG C~46 DEG C of lower temperature, it can
To prevent the decomposition of urea, pH value can keep stable, make lotion finer and smoother while greatly improving the uniformity of lotion.
As can be seen from the above technical solutions, the invention has the following advantages that
The present invention provides a kind of hand lotion with maintenance and moisture-keeping efficacy, the transdermal oligopeptides -1 in the hand lotion can
Promote the Proliferation, Differentiation of Skin Cell, improve skin resistance, so as to improve skin quality, there is maintenance effect, urea has good
Wetting and moisture-keeping function, but easily decompose, lemon triethylenetetraminehexaacetic acid rouge can prevent the decomposition of urea as the stabilizer of urea, raising
The moisture-retaining capacity of hand lotion.By experimental data it is found that hand lotion moistening effect provided in an embodiment of the present invention is significant, persistence
It is good.
Specific embodiment
The embodiment of the invention provides a kind of hand lotion and preparation method thereof with maintenance and moisture-keeping efficacy, for solving
Existing moisturizer moistening effect is not significant, unabiding problem.
It in order to make the invention's purpose, features and advantages of the invention more obvious and easy to understand, below will be to of the invention real
The technical solution applied in example is clearly and completely described, it is clear that the embodiments described below are only present invention a part
Embodiment, and not all embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creation
Property labour under the premise of all other embodiment obtained, shall fall within the protection scope of the present invention.
Embodiment 1
There is the hand lotion of maintenance and moisture-keeping efficacy using the preparation of each raw material of table 1, the specific steps are as follows:
1, Sodium Hyaluronate is added in pure water, stirs evenly and impregnates 2 hours.
2, carbomer is added, is warming up to 85 DEG C, heat-insulation soaking 30min.
3, successively put into glycerol, allantoin, methyl esters, EDTA-2Na, homogeneous 15min, homogeneous revolving speed 10000~
15000rpm。
4,10min is kept the temperature, ring five dimethyl silicone polymer, phytosterol rouge, 16/18 alcohol, propyl ester, 2- are then sequentially added
EHP, A165, monoglyceride.
5, insulated and stirred 30min, subsequent addition SIMULGEL EG, homogeneous 20min, homogeneous revolving speed 15000~
20000rpm。
6, stirring is cooled to 60 DEG C, and triethanolamine is added, and stirs 15min, 3000~3500rpm of revolving speed.
7, stirring is cooled to 45 DEG C, sequentially adds transdermal oligopeptides -1, EUXYL PE9010 preservative, SC-Glucan, accumulated snow
Careless extracting solution, BSASM, triethyl citrate, Ocean essence put into urea again after mixing evenly, discharge after mixing evenly, obtain
Hand lotion with maintenance and moisture-keeping efficacy.
1 the present embodiment of table, 1 hand lotion prepares raw material
Embodiment 2
There is the hand lotion of maintenance and moisture-keeping efficacy using the preparation of each raw material of table 2, the specific steps are as follows:
1, Sodium Hyaluronate is added in pure water, stirs evenly and impregnates 2 hours.
2, carbomer is added, is warming up to 85 DEG C, heat-insulation soaking 30min.
3, successively put into glycerol, allantoin, methyl esters, EDTA-2Na, homogeneous 15min, homogeneous revolving speed 10000~
15000rpm。
4,10min is kept the temperature, ring five dimethyl silicone polymer, phytosterol rouge, 16/18 alcohol, propyl ester, 2- are then sequentially added
EHP, A165, monoglyceride.
5, insulated and stirred 30min, subsequent addition SIMULGEL EG, homogeneous 20min, homogeneous revolving speed 15000~
20000rpm。
6, stirring is cooled to 60 DEG C, and triethanolamine is added, and stirs 15min, 3000~3500rpm of revolving speed.
7, stirring is cooled to 45 DEG C, sequentially adds transdermal oligopeptides -1, EUXYL PE9010 preservative, SC-Glucan, accumulated snow
Careless extracting solution, BSASM, Ocean essence, discharge after mixing evenly, obtain the hand lotion with maintenance and moisture-keeping efficacy.
This embodiment differs from embodiment 1 in that: it is not added with lemon triethylenetetraminehexaacetic acid rouge and urea.
2 the present embodiment of table, 2 hand lotion prepares raw material
| Raw material | Parts by weight |
| Deionized water | TO:100 |
| Glycerol | 6 |
| Allantoin | 0.5 |
| Carbomer | 1 |
| Methyl esters | 0.2 |
| EDTA-2Na | 0.05 |
| Sodium Hyaluronate | 0.3 |
| Ring five dimethyl silicone polymer | 3 |
| Phytosterol rouge | 1 |
| 16/18 alcohol | 2 |
| Propyl ester | 0.1 |
| 2-EHP | 5 |
| A165 | 3 |
| Monoglyceride | 3 |
| SIMULGEL EG | 1.2 |
| Triethanolamine | 1 |
| Transdermal oligopeptides -1 | 2 |
| EUXYL PE9010 preservative | 0.4 |
| SC-Glucan | 1 |
| Centella asiatica extract | 2 |
| BSASM | 2 |
| Ocean essence | 0.05 |
Embodiment 3
There is the hand lotion of maintenance and moisture-keeping efficacy using the preparation of each raw material of table 3, the specific steps are as follows:
1, Sodium Hyaluronate is added in pure water, stirs evenly and impregnates 2 hours.
2, carbomer is added, is warming up to 85 DEG C, heat-insulation soaking 30min.
3, successively put into glycerol, allantoin, methyl esters, EDTA-2Na, homogeneous 15min, homogeneous revolving speed 10000~
15000rpm。
4,10min is kept the temperature, ring five dimethyl silicone polymer, phytosterol rouge, 16/18 alcohol, propyl ester, 2- are then sequentially added
EHP, A165, monoglyceride.
5, insulated and stirred 30min, subsequent addition SIMULGEL EG, homogeneous 20min, homogeneous revolving speed 15000~
20000rpm。
6, stirring is cooled to 60 DEG C, and triethanolamine is added, and stirs 15min, 3000~3500rpm of revolving speed.
7, stirring is cooled to 45 DEG C, sequentially adds transdermal oligopeptides -1, EUXYL PE9010 preservative, SC-Glucan, accumulated snow
Careless extracting solution, BSASM, Ocean essence put into urea again after mixing evenly, discharge after mixing evenly, obtain with maintenance and guarantor
The hand lotion of wet effect.
The present embodiment difference from example 1 is that: be not added with lemon triethylenetetraminehexaacetic acid rouge.
3 the present embodiment of table, 3 hand lotion prepares raw material
Embodiment 4
The hand lotion that the present embodiment provides embodiment 1 and embodiment 3 carries out pH Detection of Stability, embodiment 1 and implementation
The hand lotion that example 3 is prepared is denoted as experimental group 1 and experimental group 3 respectively.
Embodiment 1 is placed in 45 DEG C of thermostatic drying chambers with hand lotion obtained by embodiment 3, pH value is observed,
It observes the period once a week, observes surrounding altogether.
As shown in table 4, the pH value for the hand lotion that embodiment 1 provides is better than experimental group 3 better than stability, is mainly reflected in it
The fluctuation range of pH value is smaller, is consistent with the desired pH range of formula design.
The pH value of 4 embodiment of table 1 hand lotion and 3 hand lotion of embodiment
| 0th week | 1st week | 2nd week | 3rd week | 4th week | |
| Experimental group 1pH value | 6.44 | 7.08 | 7.21 | 7.20 | 7.25 |
| Experimental group 3pH value | 6.76 | 7.63 | 7.92 | 8.96 | 9.12 |
Embodiment 5
The present embodiment is to detect keratoderma moisture gaining rate after the hand lotion provided using each embodiment, respectively to implement
The hand lotion that 1~embodiment of example 3 is prepared is denoted as 1~experimental group of experimental group 3, using commercially available hand lotion as control group, wherein city
Hand lotion is sold without lemon triethylenetetraminehexaacetic acid rouge.
(1) tested volunteer 10 (20-55 years old age) is selected, men and women is fifty-fifty, and experiment position is that inboard arm symmetrically selects
Take (3 × 3) cm2, left hand is check plot, and volunteer requires that any skin care must not be used in experiment position on the day before on-test
Product.
24 DEG C ± 1 DEG C of temperature is stayed in front of allowing volunteer to test every time, 10min in the environment that humidity is 50% ± 1%.Every time
Test is measured in parallel 10 times, is averaged as moisture measurement value.Blank testing value before smearing sample, is denoted as W0 controlAnd W0 experiment.It applies
It smears rear 1h, 2h, 4h and tests skin moisture content respectively, be averaged to test moisture value, be denoted as WT controlAnd WT experiment。
(2) test equipment
Derma-Expert MC760 Multi-functional skin tester
The moisture of Corneometer moisture measurement probe detection experiment position.
(3) data processing
A. sample area is denoted as Δ W in the cuticula moisture increment of all test periodsT experiment。
ΔWT experiment=(WT experiment-W0 experiment)-(WT control-W0 control)
B. sample area is calculated in the rhythmic cuticula moisture gaining rate of institute, is denoted as kt。
kt=Δ WT experiment/W0 experiment× 100%
The hand lotion that 5 experimental group of table and control group provide is to keratoderma moisture gaining rate
| 1h (%) | 2h (%) | 4h (%) | |
| Experimental group 1 | 69 | 58 | 39 |
| Experimental group 2 | 57 | 45 | 22 |
| Experimental group 3 | 67 | 53 | 34 |
| Control group | 44 | 30 | 7 |
As shown in table 5, the hand lotion that experimental group 1~3 and control group provide is descending to keratoderma moisture gaining rate
It is followed successively by experimental group 1, experimental group 3, experimental group 2, control group.Illustrate the embodiment of the present invention 1 for being added to triethyl citrate
Hand lotion moistening effect is best.In addition, the moistening effect of hand lotion of the embodiment of the present invention 2 in the case where being not added with urea according to
So it is better than commercially available hand lotion, illustrates that each component of the embodiment of the present invention has collaboration moisture-keeping function.
The above, the above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although referring to before
Stating embodiment, invention is explained in detail, those skilled in the art should understand that: it still can be to preceding
Technical solution documented by each embodiment is stated to modify or equivalent replacement of some of the technical features；And these
It modifies or replaces, the spirit and scope for technical solution of various embodiments of the present invention that it does not separate the essence of the corresponding technical solution.
Claims (10)
1. a kind of hand lotion with maintenance and moisture-keeping efficacy, which is characterized in that be made of the following components:
Glycerol, allantoin, carbomer, methyl esters, EDTA-2Na, Sodium Hyaluronate, five dimethione of ring, phytosterol rouge,
16/18 alcohol, propyl ester, 1-8 parts of 2-EHP, A165, monoglyceride, SIMULGEL EG, triethanolamine, transdermal oligopeptides -1, EUXYL
PE9010 preservative, SC-Glucan, centella asiatica extract, BSASM, urea and lemon triethylenetetraminehexaacetic acid rouge.
2. hand lotion according to claim 1, which is characterized in that by weight, described glycerol 1-8 parts, the allantois
It is 1-2 parts of 0.1-2 parts plain, the described carbomer, methyl esters 0.05-0.25 parts described, EDTA-2Na 0.01-0.08 parts described, described
0.1-0.5 parts of bright matter acid sodium, 1-5 parts of five dimethione of the ring, 0.5-1 parts of the phytosterol rouge, 16/18 alcohol
0.1-3 parts, propyl ester 0.01-0.1 parts described, 2-EHP 1-8 parts described, A165 0.1-5 parts described, the monoglyceride 0.1-4
Part, 0.5-2 parts of the SIMULGEL EG, triethanolamine 1-2 parts described, -1 0.5-2 parts of the transdermal oligopeptides, the EUXYL
0.1-0.5 parts of PE9010 preservative, SC-Glucan 0.1-2 parts described, the centella asiatica extract 0.1-2 parts described, BSASM
0.1-3 parts, it is urea 5-20 parts described, 0.5-5 parts of lemon triethylenetetraminehexaacetic acid rouge described.
3. hand lotion according to claim 2, which is characterized in that by weight, further includes: 0.01-0.08 parts of essence.
4. hand lotion according to claim 2, which is characterized in that by weight, 2~6 parts of the glycerol, the allantois
Element 0.3~1 part, 1~1.5 part of the carbomer, 0.15~0.2 part of the methyl esters, 0.05~0.08 part of the EDTA-2Na,
0.2~0.4 part of the Sodium Hyaluronate, 3~5 parts of five dimethione of the ring, 0.8~1 part of the phytosterol rouge, institute
It is sweet to state 1~3 part of 16/18 alcohol, 0.05~0.1 part of the propyl ester, 3~6 parts of the 2-EHP, 3~5 parts of the A165, the list
It is 2~4 parts of rouge, 1~2 part of the SIMULGEL EG, 1~2 part of the triethanolamine, -1 1~2 part of the transdermal oligopeptides, described
It is 0.2~0.5 part of EUXYL PE9010 preservative, 1~2 part of the SC-Glucan, 1~2 part of the centella asiatica extract, described
It is 1~3 part of BSASM, 10~15 parts of the urea, 2~5 parts of lemon triethylenetetraminehexaacetic acid rouge described.
5. hand lotion according to claim 4, which is characterized in that by weight, 6 parts of the glycerol, the allantoin
0.5 part, 1 part of the carbomer, 0.2 part of the methyl esters, 0.05 part of the EDTA-2Na, 0.3 part of the Sodium Hyaluronate, institute
State 3 parts of five dimethione of ring, 1 part of the phytosterol rouge, 2 parts of 16/18 alcohol, 0.1 part of the propyl ester, the 2-
It is 5 parts of EHP, 3 parts of the A165,3 parts of the monoglyceride, 1.2 parts of the SIMULGEL EG, 1 part of the triethanolamine, described
- 12 part of transdermal oligopeptides, 0.4 part of the EUXYL PE9010 preservative, 1 part of the SC-Glucan, the centella asiatica extract
2 parts, it is 2 parts of the BSASM, 12 parts of the urea, 3 parts of lemon triethylenetetraminehexaacetic acid rouge described.
6. the preparation method of hand lotion described in claim 1 to 5 any one, which comprises the following steps:
Step 1: after Sodium Hyaluronate is diluted, carbomer is added, obtains the first product；
Step 2: sequentially adding glycerol, allantoin, methyl esters and EDTA-2Na in the first product of Xiang Suoshu and carry out the first homogeneous, obtain
Second product；
Step 3: sequentially added in the second product of Xiang Suoshu ring five dimethyl silicone polymer, phytosterol rouge, 16/18 alcohol, propyl ester,
2-EHP, A165 and monoglyceride mixing, obtain third product；
Step 4: SIMULGEL EG being added in Xiang Suoshu third product and carries out the second homogeneous, obtains the 4th product；
Step 5: being mixed triethanolamine is added in the 4th product, obtain the 5th product；
Step 6: after the 5th product is cooled to 44 DEG C~46 DEG C, sequentially adding transdermal oligopeptides-in the 5th product of Xiang Suoshu
1, after EUXYL PE9010 preservative, SC-Glucan, centella asiatica extract, BSASM and triethyl citrate are mixed, then
Urea is added, obtains hand lotion.
7. preparation method according to claim 6, which is characterized in that after addition carbomer described in step 1, obtain described
Before first product, further includes: be heated to 85 DEG C~90 DEG C, keep the temperature 2h~2.5h.
8. preparation method according to claim 6, which is characterized in that the revolving speed of the first homogeneous described in step 2 be 10000~
15000rpm, the time of first homogeneous are 20min~30min.
9. preparation method according to claim 6, which is characterized in that the revolving speed of the second homogeneous described in step 4 be 15000~
20000rpm, the time of second homogeneous are 20min~30min.
10. preparation method according to claim 6, which is characterized in that before the addition triethanolamine described in step 5, also
It include: that the 4th product is cooled to 60 DEG C~65 DEG C.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110755280A (en) * | 2019-11-03 | 2020-02-07 | 广州悦荟化妆品有限公司 | Moisturizing and repairing hand mask |
| CN112515992A (en) * | 2020-12-08 | 2021-03-19 | 上海家化联合股份有限公司 | Stable composition comprising triethyl citrate and glycine |
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Application publication date: 20190507 |