CN109692324B

CN109692324B - It is a kind of to disappear the Chinese medicine hydrogel emplastrum and preparation method thereof of rouge for subtracting tripe

Info

Publication number: CN109692324B
Application number: CN201910225925.9A
Authority: CN
Inventors: 陈浩; 张琦; 王万春; 管咏梅; 严张仁; 易军; 陈琦; 项凤梅; 刘志勇; 曾晶晶; 张倩
Original assignee: Jiangxi University of Traditional Chinese Medicine
Current assignee: Jiangxi University of Traditional Chinese Medicine
Priority date: 2019-03-25
Filing date: 2019-03-25
Publication date: 2019-06-25
Anticipated expiration: 2039-03-25
Also published as: CN109692324A

Abstract

Disappear the Chinese medicine hydrogel emplastrum of rouge the invention discloses a kind of for subtracting tripe, comprising base material and the Chinese medicine ointment for being attached to substrate material surface, the Chinese medicine ointment is made of the Chinese medicine composition comprising following components: fructus cannabis, Cortex Magnoliae Officinalis, the dried immature fruit of citron orange, cassia seed, aloe, lotus leaf, Fructus Crataegi, rhizoma alismatis, corn stigma, rhizoma atractylodis, dried orange peel, blood clam, Radix Salviae Miltiorrhizae, safflower, luffa, turmeric, Radix Curcumae, Cortex Phellodendri, Asian puccoon, asarum, moxa, rhizoma zingiberis and indigo naturalis.Chinese medicine hydrogel emplastrum of the invention makes all medicine fragrance in emplastrum walk to alter, percutaneous permeation for being attached to the abdomen of fat accumulation, temperature is played through qi-regulating, opens channels and collaterals, in the table that has a thorough knowledge of up and down, play the role of activating microcirculation and removing stasis medicinal, relax bowel and defecation, it is good to the therapeutic effect of simple obesity patient.Clinical test verifying, using more than 2 courses for the treatment of of emplastrum of the present invention can effectively subtracting tripe removal stomach fat, total effective rate is and simple and easy to use up to 86.7%, and lesion of going directly, easy to clean, patient is easy to use.

Description

It is a kind of to disappear the Chinese medicine hydrogel emplastrum and preparation method thereof of rouge for subtracting tripe

Technical field

The present invention relates to Chinese herbs paste technical fields, and in particular to it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum and Preparation method.

Background technique

Simple obesity is the most common Dystrophy in modern society, is referred to without specific endocrine, something lost Reason is passed, causes adipose tissue to accumulate the disease for excessively causing weight extraordinary in vivo due to taking in heat and being more than the heat of consumption Disease.The most obvious feature of Simple Obesity Patient is that fat can be concentrated and be piled up in abdomen.It is interior because of natural endowment spleen deficiency, it is outer because of overfeeding Delicious food, few labor is mostly sleeping, causes deficiency of the spleen causing weakness of QI, life in phlegm wet；Or older deficiency of the kidney, imbalance of yin and yang, phlegm-blood stasis inner product can make in turbid pathogenic factor It is raw, stop up product in vivo, and it is fat to cause fat.Simple obesity is one of the most common type in all kinds of obesities, and account for about obese people 95% is left It is right.

China's Traditional Chinese Medicine early has research for fat, it is believed that obesity is mostly the disease of asthenia in origin and asthenia in superficiality.This void is with the deficiency of vital energy It is main, if simultaneous imbalance of yin and yang, can there are the deficiency of yang or the gas deficiency of Yin, the disease being located in the spleen, kidney, liver, gallbladder, the heart, lung, clinic are based on spleen deficiency gas kidney, liver Gallbladder catharsis imbalance is also visible.Mark it is real with cream rouge, phlegm it is turbid based on, often have water-wet concurrently, also not and blood stasis, stagnation of the circulation of vital energy person.

Also have much to the traditional therapy of simple obesity.It common are dietary therapy method, exercise therapy method, west Medicine, Chinese medicine, needle thorn, catgut implantation at acupoint, moxa-moxibustion, massage, operation etc..

Modern medicine treats the medication of obesity, is concentrated mainly on gastrointestinal lipase depressant (such as orlistat), pancreas Island element sensitizer melbine, anorectic (such as sibutramine), slimming drugs (such as leptin), the surgery hand for acting on novel targets Art treatment, gene therapy etc., but in the presence of such as orlistat, expensive, medication has dispute, melbine needle in treatment Clear to treatment Obesity-type Polycystic Ovary Syndrome mechanism of action, sibutramine adverse reaction is larger, safety is poor, surgery hand Art medical expense is higher, cumbersome, and the oral medicine for acting on novel targets is less, in gene therapy there are gene expression regulation, Many problems such as signal transduction.And all Western medicine are not directed to the specific drug of clinical abdominal fat accumulation adiposis patient.

Diet control and exercise therapy simple obesity, then be aided with drug therapy and have a certain effect, but diet control and Exercise therapy is difficult to adhere to, unsatisfactory curative effect.

The methods of Chinese medicine such as acupuncture, catgut implantation at acupoint haves the characteristics that patient compliance is poor.

Summary of the invention

In order to solve the above problem of the prior art, the present invention provides a kind of safe and effective Chinese medicine hydrogel emplastrum.

In contrast, that there are lotion residue adhesions is viscous at the place of sticking for black plaster such as compound Nanxing pain paste, hippocampus panchrest plaster Attached skin not easy cleaning, residue pollution clothes the problems such as.Especially in southern hygrothermal environment, user can especially take notice of this kind of The comfort of externally used paste；And this patent design research and development it is a kind of subtract tripe disappear rouge Chinese medicine hydrogel emplastrum the place of sticking not Only be easy to wash with water, and will not pollution clothes, sticking patient for a long time there will not be discomfort.

This Chinese medicine hydrogel emplastrum is used to be attached to the abdomen of fat accumulation, and all medicine fragrance in emplastrum is made to walk to alter, percutaneously Diffusion plays temperature through qi-regulating, opens channels and collaterals, in the table that has a thorough knowledge of up and down, play activating microcirculation and removing stasis medicinal, relax bowel and defecation, effectively accelerates disease The metabolism of trouble improves microcirculation, gradually consumes stomach fat, is disappeared rouge with having the function that subtract tripe.

(2) technical solution

In order to achieve the above object, the main technical schemes that the present invention uses include:

It is a kind of to disappear the Chinese medicine hydrogel emplastrum of rouge for subtracting tripe, comprising base material and it is attached in substrate material surface Medicine ointment, on prescription screening, finding patient by clinical research, there are constipation using rheum officinale some patientss after rheum officinale, are deactivated The phenomenon that；Folium sennae should not use the weakness of the spleen and the stomach patient；Then the efficacy of a drug is too quickly for saltcake, the root of gansui, crotons, is not easy to allow sufferer for a long time It uses；Therefore above-mentioned traditional Chinese medicine of the five flavours is excluded in prescription.The rear Chinese medicine ointment is finally screened by the Chinese medicine comprising following components Composition is made: fructus cannabis, Cortex Magnoliae Officinalis, the dried immature fruit of citron orange, cassia seed, aloe, lotus leaf, Fructus Crataegi, rhizoma alismatis, corn stigma, rhizoma atractylodis, dried orange peel, watt Stupefied son, Radix Salviae Miltiorrhizae, safflower, luffa, turmeric, Radix Curcumae, Cortex Phellodendri, Asian puccoon, asarum, moxa, rhizoma zingiberis and indigo naturalis.

It is further preferred that the Chinese medicine composition is according to the mass fraction, include: 50~70 parts of fructus cannabis, Cortex Magnoliae Officinalis 50~ 70 parts, 25~35 parts of the dried immature fruit of citron orange, 35~55 parts of cassia seed, 50~70 parts of aloe, 65~90 parts of lotus leaf, 35~55 parts of Fructus Crataegi, pool Rush down 25~35 parts, 65~90 parts of corn stigma, 25~35 parts of rhizoma atractylodis, 35~55 parts of dried orange peel, 35~55 parts of blood clam, Radix Salviae Miltiorrhizae 35~55 Part, 65~90 parts of safflower, 65~90 parts of luffa, 25~35 parts of turmeric, 25~35 parts of Radix Curcumae, 35~55 parts of Cortex Phellodendri, Asian puccoon 35 ~55 parts, 35~55 parts of asarum, 180~250 parts of moxa, 60~110 parts of rhizoma zingiberis and 10~20 parts of indigo naturalis.

It is further preferred that the Chinese medicine composition is according to the mass fraction, include: 60 parts of fructus cannabis, 60 parts of Cortex Magnoliae Officinalis, the dried immature fruit of citron orange 30 parts, it is 45 parts of cassia seed, 60 parts of aloe, 75 parts of lotus leaf, 45 parts of Fructus Crataegi, 30 parts of rhizoma alismatis, 75 parts of corn stigma, 30 parts of rhizoma atractylodis, old 45 parts of skin, 45 parts of blood clam, 45 parts of Radix Salviae Miltiorrhizae, 75 parts of safflower, 75 parts of luffa, 30 parts of turmeric, 30 parts of Radix Curcumae, 45 parts of Cortex Phellodendri, purple Careless 45 parts, 45 parts of asarum, 225 parts of moxa, 90 parts of rhizoma zingiberis, 15 parts of indigo naturalis.

Crude drug source in the Chinese medicine composition meets following one or more of qualifications:

The Fructus Crataegi originates from Shandong；

The dried orange peel originates from Guangdong；

The safflower originates from Xinjiang；

The Asian puccoon originates from Xinjiang；

The dried immature fruit of citron orange originates from Jiangxi；

The lotus leaf originates from Jiangxi；

The asarum originates from Liaoning；

The rhizoma atractylodis originate from Liaoning；

The Cortex Phellodendri originates from Liaoning.

It is further preferred that in the Chinese medicine composition, lotus leaf, corn stigma, safflower, luffa mass ratio be 1:1:1: 1；The mass ratio of Asian puccoon and Cortex Phellodendri is 1:1.

The present invention also provides it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation method, walked for following technique It is rapid:

S1: standby medicinal material: in parts by weight, weigh 50~70 parts of fructus cannabis, 50~70 parts of Cortex Magnoliae Officinalis, 25~35 parts of the dried immature fruit of citron orange, 35~55 parts of cassia seed, 50~70 parts of aloe, 65~90 parts of lotus leaf, 35~55 parts of Fructus Crataegi, 25~35 parts of rhizoma alismatis, corn stigma 65 ~90 parts, 25~35 parts of rhizoma atractylodis, 35~55 parts of dried orange peel, 35~55 parts of blood clam, 35~55 parts of Radix Salviae Miltiorrhizae, safflower 65~90 part, thread 65~90 parts of melon network, 25~35 parts of turmeric, 25~35 parts of Radix Curcumae, 35~55 parts of Cortex Phellodendri, 35~55 parts of Asian puccoon, asarum 35~55 Part, 180~250 parts of moxa, 60~110 parts of rhizoma zingiberis and 10~20 parts of indigo naturalis；

S2: alcohol extracting: Cortex Magnoliae Officinalis investment being filled in the tank of ethyl alcohol, 1 ~ 2h of heating extraction, and filtering, collection and merging filtrate are received Collect supernatant, be evaporated under reduced pressure recycling ethyl alcohol, be concentrated into 1.05~1.20(40 DEG C of relative density) magma A；

S3: water mentions: by the blood clam throwing of Cortex Magnoliae Officinalis, cassia seed and gauze package after corn stigma, lotus leaf, luffa, alcohol extracting Enter to fill in the tank of water, heating, which decocts, extracts 1 ~ 2h, and safflower, the dried immature fruit of citron orange, Fructus Crataegi, aloe, Radix Salviae Miltiorrhizae, fire fiber crops are then added into tank Benevolence, rhizoma alismatis, rhizoma atractylodis, dried orange peel, Cortex Phellodendri, turmeric and Radix Curcumae, heating, which decocts, extracts 1~2h, and merging filtrate is collected in filtering, and decompression is steamed Hair concentration, obtain relative density be 1.05 ~ 1.20(40 DEG C) magma B；

S4: moxa, rhizoma zingiberis, the volatile oil in asarum are extracted, mixture of volatile oil C is obtained；

S5: Asian puccoon is set and is fried in oil cauldron (frequently with sesame oil) to oil in aubergine, is removed slag, filters, obtains filtered fluid D；

S6: magma A, magma B are mixed and cools and then is freeze-dried at room temperature, are milled to powder, adds distilled water Dissolve to obtain medical fluid E;

S7: indigo naturalis is dissolved in ethyl alcohol and obtains solution F；

S8: filtrate D is mixed with solution F, filter and remove residue obtains medical fluid G；

S9: will volatilize oil mixture C and diluted with ethyl alcohol, and auxiliary materials and mixing is added and stirs evenly again with medical fluid G, adds later Medical fluid E and auxiliary material are sufficiently stirred to obtain hydrogel semisolid ointment；The accessory package aqueous gel auxiliary material；

S10: the hydrogel semisolid ointment is applied on base material, and hydrogel emplastrum is made.

Further after slice, removal moisture drying, Chinese medicine hydrogel emplastrum product is made in sealed package.

Preferably, in step s 2, the alcohol extracting heating temperature is 60 ~ 90 DEG C, and under conditions of vacuum tightness, reflux It extracts, each 1 ~ 2h of refluxing extraction, extracts 2 ~ 3 times in total, merge each secondary filtrate after having extracted, collect supernatant.

Preferably, in step s3, it is 80 ~ 110 DEG C that the heating that the water mentions, which decocts temperature, under conditions of closed, always It extracts 2 ~ 3 times altogether, decocts extract 1 ~ 2h every time, merge each secondary filtrate after having extracted.

Preferably, in step s 4, it is described extract moxa, rhizoma zingiberis, Herba Asari volatile oil method be: by moxa, rhizoma zingiberis, thin It is pungent to be put into light oil extractor, using 5~9h of extraction by steam distillation.

Wherein, in step s 4, it is described extract moxa, rhizoma zingiberis, Herba Asari volatile oil method can also use supercritical CO 2 Extractive technique is extracted；Or first handled with cellulase, fermented 3 ~ 8 days in 40 ~ 50 DEG C, the raw material after fermentation is added 4 ~ 6 times 50 ~ 60% ethyl alcohol of weight extracts 2 ~ 3 times using continuous flow upstream ultrasonic extraction, then through petroleum ether or ether to get volatile oil.

Preferably, in step s 5, Asian puccoon is drenched with water, be placed in oil cauldron internal control liquefaction temperature at 60~250 DEG C, fry to Oil is in aubergine.

Preferably, it is in step S6 detailed process;By magma A, magma B mix cool at room temperature, be put into -10 DEG C~- It is frozen into ice in 30 DEG C of refrigerators, is then transferred in freeze drier and forms powder, is then added according to 120g ~ 210g powder 250~420mL purified water dissolves to obtain medical fluid E.

Preferably, in the step s 7, the indigo naturalis is dissolved in 50mL~150mL dehydrated alcohol by 10 ~ 20g.

Preferably, in step s 9, the auxiliary material is the polyacrylic acid neutralized by the part HQ841 or HQ800() hydrogel Resin-oatmeal and glycerol, CMC-Na(sodium carboxymethylcellulose), PVPP(polyvinylpyrrolidone), Dihydroxyaluminium Aminoacetate, EDETATE DISODIUM, PVPK120(povidone, hydrogel tackifier), 10% aqueous tartaric acid solution, NP-700(pharmaceutical grade Sodium Polyacrylate), menthol, Borneol, 95% ethyl alcohol, azone (: 1- orthododecyl nitrogen heterocyclo heptane-2-ketone, dermal osmosis accelerator), in DMDMH(dimethyl second Uride, broad-spectrum high efficacy antiseptic and antibiotic agent), propylene glycol, one or more of ethyl hydroxy benzoate be mixed.

Fried Groomwell root oil external application antiallergy, the effect of promoting blood circulation are than more significant, major function: clearing heat and detoxicating, swelling and pain relieving.

HQ841 hydrogel resin powder is the polyacrylic bar cloth of Huaibei Hui Qiang high molecular material Co., Ltd stand-alone development Agent pharmaceutical carrier, the material non-toxic, tasteless, non-stimulated to skin, manufactured colloid is good with skin compatibility, and easy sticker is easily taken off, no Pain skin can be taken off, drugloading rate is big, can enter blood circulation by aquation and Transdermal absorption, drug, avoid the first mistake of liver Effect, targeting is strong, is to replace the optimal pharmaceutical carrier of traditional hot-melt adhesive cataplasm at present.Pharmaceutical grade azone is for preparing cream Agent, creme, suppository, film, paste, liniment etc. are remarkably improved curative effect of medication, reduce dosage and side effect.Such as: adding azone About 0.02% clindamycin and 0.1% clindamycin effect having the same, antineoplastic " 5 FU 5 fluorouracil " is middle to be added 1% azone, penetrating power improve 80 times, and 5% azone can make the utilization rate " stabilized " improve 45 times etc..Azone is answered simultaneously With past medicine for oral administration may be made to be changed to externally applied drug.For azone for emplastrum of losing weight, dosage is 0.5~1%, that is, is greatly improved skin Assimilation effect of the skin to effective component.

HQ800 is the polyacrylic acid that part neutralizes, and degree of neutralization is 35%, COOH:COONa=65:35.

(3) beneficial effect

The tripe provided by the invention that subtracts disappears the Chinese medicine hydrogel emplastrum of rouge, is particularly suitable for the sufferer of simple obesity, emplastrum The ointment of upper load is good to the therapeutic effect of simple obesity patient, can directly act on the abdomen that fat concentrates accumulation, Subtract tripe removal stomach fat, it is efficient up to 86.7%.

The of the invention tripe rouge Chinese medicine hydrogel emplastrum that disappears that subtracts can be directly pasted at the navel of user, lesion of going directly, Tear rear easy to clean, easy to use, patient compliance is good.

Chinese medicine hydrogel emplastrum of the invention can closely be attached to application on human skin surface, not easily lead to that lotion is thinning, lateral overflows Out the problems such as, solve traditional black plaster lotion residual, pollution clothes, tear difficult, ixoderm the defects of.

Detailed description of the invention

Fig. 1 is the preparation technology flow chart of the Chinese medicine hydrogel emplastrum of present pre-ferred embodiments.

Specific embodiment

For a better understanding of the present invention, preparation process flow of the invention is specifically addressed with reference to the accompanying drawing, But it is not construed as limiting the present invention, nonessential is changed according to some of foregoing invention content for those skilled in the art Into with adjustment, be also considered as and be within the scope of the present invention.

As shown in Figure 1, for the embodiment of the present invention for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation process flow Figure.As shown in Figure 1, it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation method, be following processing step:

S1: it weighs medicinal material: in parts by weight, weighing 50~70 parts of fructus cannabis, 50~70 parts of Cortex Magnoliae Officinalis, the dried immature fruit of citron orange 25~35 Part, 35~55 parts of cassia seed, 50~70 parts of aloe, 65~90 parts of lotus leaf, 35~55 parts of Fructus Crataegi, 25~35 parts of rhizoma alismatis, corn It must 65~90 parts, 25~35 parts of rhizoma atractylodis, 35~55 parts of dried orange peel, 35~55 parts of blood clam, 35~55 parts of Radix Salviae Miltiorrhizae, safflower 65~90 Part, 65~90 parts of luffa, 25~35 parts of turmeric, 25~35 parts of Radix Curcumae, 35~55 parts of Cortex Phellodendri, 35~55 parts of Asian puccoon, asarum 35 ~55 parts, 180~250 parts of moxa, 60~110 parts of rhizoma zingiberis and 10~20 parts of indigo naturalis.

S2: alcohol extracting: Cortex Magnoliae Officinalis investment is filled in the tank of ethyl alcohol, and filtrate is collected by filtration in 1 ~ 2h of heating extraction, collects supernatant Liquid, be evaporated under reduced pressure recycling ethyl alcohol, be concentrated into 1.05~1.20(40 DEG C of relative density) magma A.

S3: water mentions: by the blood clam throwing of Cortex Magnoliae Officinalis, cassia seed and gauze package after corn stigma, lotus leaf, luffa, alcohol extracting Enter to fill in the tank of water, heating, which decocts, extracts 1 ~ 2h, and safflower, the dried immature fruit of citron orange, Fructus Crataegi, aloe, Radix Salviae Miltiorrhizae, fire fiber crops are then added into tank Benevolence, rhizoma alismatis, rhizoma atractylodis, dried orange peel, Cortex Phellodendri, turmeric and Radix Curcumae, heating, which decocts, extracts 1~2h, and merging filtrate is collected in filtering, and decompression is steamed Hair concentration, obtain relative density be 1.05 ~ 1.20(40 DEG C) magma B.

S4: moxa, rhizoma zingiberis, the volatile oil in asarum are extracted, mixture of volatile oil C is obtained.

S5: Asian puccoon is set and is fried in oil cauldron to oil in aubergine, is removed slag, filters, obtains filtered fluid D.

S6: magma A, magma B are mixed and is freeze-dried, is milled to powder, distilled water is added to dissolve to obtain medical fluid E.

S7: indigo naturalis is dissolved in ethyl alcohol and obtains solution F.

S8: filtrate D is mixed with solution F, filter and remove residue obtains medical fluid G.

S9: will volatilize oil mixture C and diluted with ethyl alcohol, and relevant auxiliary materials mixing is added and stirs evenly again with medical fluid G, Zhi Houzai Medical fluid E and relevant auxiliary materials are added, are sufficiently stirred to obtain hydrogel semisolid ointment；The accessory package aqueous gel auxiliary material.

It should be noted that as shown in connection with fig. 1: these steps of above step S2 ~ S5, S7 can be parallel or overturn operation Sequentially；S6 need to after step S2 ~ S3, but can also with S4-S5, S7 parallel or reverse operation order；S8 need to after S5, S7, But can also with S6 parallel or reverse operation order.In short, it will be understood by those skilled in the art that intelligible, process above step Not comprising inevitable sequencing relationship, the processing result that must only rely on previous step is just achievable.

In the traditional Chinese medicinal components for playing drug action in emplastrum of the invention, the function of each component is as follows: Cortex Magnoliae Officinalis, aromatization Wet Chinese medicine, the major functions: stagnation of QI due to dyspepsia；Abdominal distention constipation；Damp retention in middle-jiao, abdominal swelling and diarrhea；Phlegm stops up the circulation of vital energy in the wrong direction；Chest full of cough.

Fructus cannabis has the effect of relax bowel and defecation.It is usually used in blood deficiency and depleted fluid, dry constipation of intestines.

The dried immature fruit of citron orange, " drugization justice " record the dried immature fruit of citron orange and specially let out stomach excess, convince hard knot by patient analysis, therefore the main middle part of gastric cavity treats the interventral reality of navel to control blood system Full, dissolving phlegm addiction dispels and cuts off the water, and eats by place, breaks accumulation of pathogens in chest, and defaecation is closed, it is non-this cannot.

Cassia seed bitter, sweet, salty, cold nature enters liver, kidney, large intestine channel；Constipation and height are treated in relax bowel and defecation, lipid-loweringing improving eyesight Blood lipid, hypertension.It clears liver and improve vision, sharp water defaecation has laxative action, reducing blood pressure and blood fat.

Aloe, nature and flavor: it is bitter, it trembles with fear.For purging intense heat；Removing toxic substances；Stagnation resolvation；Desinsection.Argument is red；Constipation etc..

Lotus leaf has the effect of summer heat relieving and dampness eliminating, invigorating the spleen rising Yang, dissipating stasis and stanching bleeding.Cure mainly hot summer weather polydipsia, headache and dizziness, oedema, Deficiency of food abdominal distension.Lotus leaf has very strong effect of weight reducing, have promote intestines peristalsis, exclude toxin, draining diuresis, health disappear rouge, richness Leptin containing tea, the rate of metabolism for improving body.

Fructus Crataegi has promoting digestion and removing indigestion, reduces blood lipid and mitigates the curative effect of artery sclerosis, dissipates for food digesting stomach fortifying, promoting the circulation of qi The stasis of blood.

Rhizoma alismatis nature and flavor: it is sweet, it trembles with fear.Effect: Li Shui, excreting dampness heat, row phlegm retention expel the heat-evil.Control difficult urination, edema swelling, dysentery Deng.

Corn stigma has treating stranguria, the effect of calming the liver and benefiting the lungs that expels the heat-evil.

Rhizoma atractylodis nature and flavor are arduous, temperature.With drying damp and strengthening spleen, the effect of it is turbid to ward off dirtyization, expelling wind and clearing away cold, improving eyesight.Cure mainly wet tired spleen Stomach, gastral cavity ruffian abdominal distension, vomiting and diarrhea, lower stranguria with turbid discharge of band.Rhizoma atractylodis and Cortex Magnoliae Officinalis, dried orange peel compatibility transport spleen, relieving QI stagnancy in the stomach with eliminating dampness.

Dried orange peel has regulating qi-flowing for strengthening spleen, and in tune, eliminating dampness, resolving sputum, the abdominal fullness and distention for curing mainly the taste stagnation of the circulation of vital energy or pain, digestion are not It is good.

Blood clam is to enhance the promoting flow of qi and blood circulation, and the function of dissipating bind eliminating mass, the gastral cavilty phlegm that disappears is long-pending, and softening and eliminating sputum, resolving sputum helps digestion.

The effect of Radix Salviae Miltiorrhizae has promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle.For chest impediment and cardialgia, the stomach duct and abdomen side of body Bitterly, lump in the abdomen lump in the abdomen is gathered, the diseases such as hot numbness pain.

Safflower can blood circulation, removing blood stasis and acesodyne, facilitate controlling through closing, dysmenorrhea, lochia, chest impediment and cardialgia, stasis of blood, Pricking pain in the chest, traumatic injury, sore swell and ache curative curative effect.There is the effect of activating microcirculation and removing stasis medicinal, dissipate wet effect going to swell.

Luffa has the effect of clearing and activating the channels and collaterals, removing toxicity for detumescence.

Turmeric cures mainly chest and abdomen swelling and pain, shoulder arm numbness pain, it is pained unbearably, postpartum blood pain, ringworm sore is initial, irregular menstruation, amenorrhoea etc..

Radix Curcumae acrid flavour, hardship, it is cool in nature；Return heart, liver, gallbladder channel；Fragrance reaches thoroughly, and can rise can drop, and has the promoting flow of qi and blood circulation, soothing the liver solution It is strongly fragrant, the effect of waking up the patient from unconsciousness by clearing away heart fire, clearing heat and cooling blood.Cure mainly chest side of body epigastric pain, irregular menstruation, dysmenorrhea menostasis etc..

Cortex Phellodendri has the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice and reddish urine is used for the deficiency of Yin Hyperactivity of fire, night sweat hectic fever due to yin.

Its nature and flavor of indigo naturalis are salty-cold, have effects that clearing heat and detoxicating, blood cooling and ecchymoses removing, clearing liver-fire, arresting convulsion.Can heat-clearing, cool blood, Removing toxic substances.Warm disease excess heat is controlled, heat removing and detoxication, and can cool blood.

Asarum has the effect of expelling wind and clearing away cold, sensible analgesic, warming lung and resolving fluid.Volatile argyi leaf oil has clearing and activating the channels and collaterals, promoting blood circulation The effects of stagnation resolvation.Rhizoma Zingiberis volatile oil has warming spleen and stomach for dispelling cold, recover Yang and smooth venation, the effect of eliminating dampness dissolving phlegm.Herba Asari volatile oil has wind-dispelling The effect of cold dispelling, sensible analgesic, warming lung and resolving fluid.The volatile oil of rhizoma zingiberis, asarum and moxa shares, and can promote all medicines virtue in emplastrum Perfume (or spice) walks to alter, percutaneous permeation, plays temperature through qi-regulating, opens channels and collaterals, and upper inferior effect, helps other effective components in the table that has a thorough knowledge of Absorb the diffusion with the vital organs of the human body in vivo.

Fried Asian puccoon has very significant curative effect to eczema, skin allergy.Application on human skin can be reduced to hydrogel plaster with fried Asian puccoon The allergy of cream improves patient to the compliance of emplastrum of the present invention.

Cassia seed relax bowel and defecation, aloe let out lower clearing liver, Fructus Crataegi digestion-promoting spleen-invigorating, scattered stasis, blood clam resolving hard lump, and four Person can help fructus cannabis, Cortex Magnoliae Officinalis, dried immature fruit of citron orange promoting the circulation of qi dissipate-swelling except full.Rhizoma atractylodis are eliminating dampness and eliminating phlegm, and dried orange peel is eliminating dampness and eliminating phlegm, the wide chest of qi-regulating, and the two can Play the function of eliminating dampness dissolving phlegm.Lotus leaf clearing away summer-heat and eliminating dampness, hair tonic are positive clearly, and rhizoma alismatis clearing damp and promoting diuresis, expelling the heat-evil are turbid, corn stigma inducing diuresis to remove edema, and three Person can play the benefits of accumulateing in neutralizing phlegm wet.Radix Salviae Miltiorrhizae, safflower, which are invigorated blood circulation, leads to the stasis of blood, and luffa is promoting blood circulation and removing obstruction in channels, and turmeric breaking blood and promoting the circulation of qi, promoting menstruation stop Bitterly, Radix Curcumae soothing liver-qi stagnation, promoting blood circulation and stopping pain.Five share the metabolism that can effectively accelerate sufferer, improvement patient's microcirculation. Asarum, moxa, rhizoma zingiberis be thoroughly in promoting menstruation make medicine, enable all medicine fragrance walk to alter, temperature opens channels and collaterals through qi-regulating, in the table that has a thorough knowledge of on Under.Indigo naturalis is clearing heat and detoxicating, clearing liver-fire, Cortex Phellodendri heat-clearing and damp-drying drug, and fried Asian puccoon has very significant curative effect three to eczema, skin allergy It shares and the allergy that patient sticks the generation of this patch can be effectively prevented.

It further illustrates with reference to embodiments.

Embodiment 1

A kind for the treatment of subtracts tripe and disappears the Chinese medicine hydrogel emplastrum of rouge, and the effective component of ointment is by following Chinese medicine composition system : fructus cannabis 60g, Cortex Magnoliae Officinalis 60g, dried immature fruit of citron orange 30g, 45 g of cassia seed, 60 g of aloe, 75 g of lotus leaf, 45 g of Fructus Crataegi, rhizoma alismatis 30 G, 75 g of corn stigma, rhizoma atractylodis 30g, 45 g of dried orange peel, blood clam 45g, Radix Salviae Miltiorrhizae 45g, safflower 75g, luffa 75g, turmeric 30g, strongly fragrant 30 g of gold, 45 g of Cortex Phellodendri, Asian puccoon 45g, asarum 45g, moxa 225g, rhizoma zingiberis 90g, 15 g of indigo naturalis.

With above-mentioned medicinal material component, of the invention a kind of disappear rouge for subtracting tripe is prepared according to processing step shown in FIG. 1 Chinese medicine hydrogel emplastrum, in the present embodiment the specific steps of which are as follows:

S1: prepare medicinal material according to above-mentioned parts by weight.

S2: Cortex Magnoliae Officinalis being set, ethanol in proper amount be added in stainless steel Chinese medicine extracting tank, and 80 DEG C of extractions are extracted 1.5h, filtered, collect Filtrate.Extract 2 times, merging filtrate, collect supernatant, and ethyl alcohol is recovered under reduced pressure, be concentrated into 1.06(40 DEG C of relative density) left and right Magma A.

S3: the blood clam that Cortex Magnoliae Officinalis, cassia seed and the gauze after corn stigma, lotus leaf, luffa, alcohol extracting wrap up is set stainless Be added suitable quantity of water in steel Chinese medicine extracting tank, 80 DEG C of heating, which decoct, extracts 2h, then be added in extractor safflower, the dried immature fruit of citron orange, Fructus Crataegi, Aloe, Radix Salviae Miltiorrhizae, 80 DEG C of fructus cannabis, rhizoma alismatis, rhizoma atractylodis, dried orange peel, Cortex Phellodendri, turmeric, Radix Curcumae heating decoct and extract 1h, and filter is collected by filtration Liquid.Extract 2 times, merging filtrate is concentrated into 1.1(40 DEG C of relative density) left and right magma B.

S4: moxa, rhizoma zingiberis, asarum are extracted using extraction by steam distillation 9h and obtains volatile oil C.S5: Asian puccoon is taken to set oil cauldron Interior, Oil-temperature control is 140 DEG C and fries to oil in aubergine, removes slag, filter to get filtrate D.

S6: take above magma A, B be uniformly mixed be put into freezed in -20 DEG C of refrigerators after place into and form powder in freeze drier End is added 300mL purified water and dissolves to obtain medical fluid E.

S7: it takes indigo naturalis to be dissolved in 100mL dehydrated alcohol and obtains medical fluid F.

S8: medical fluid F and filtrate D being mixed and is filtered, and is stood 2h and is obtained medical fluid G.

S9: will volatilize after oily C dilutes 4 times with ethyl alcohol, and glycerol, EDETATE DISODIUM, CMC-Na, PVPP, HQ841, sweet is added It after the auxiliary materials such as hydroxyl aluminium, azone, stirs evenly, adds medical fluid G mixing, be eventually adding medical fluid E and PVPK120,10% winestone sour water Hydrogel semisolid ointment is sufficiently stirred evenly to obtain after the auxiliary materials such as solution, menthol, borneol, 95% ethyl alcohol, DMDMH.

S10: semisolid ointment is applied on nonwoven fabric base bottom material, hydrogel patch is obtained.After removal moisture drying, sealing packet Fill to obtain Chinese medicine external hydrogel emplastrum.

Embodiment 2

A kind for the treatment of subtracts tripe and disappears the Chinese medicine hydrogel emplastrum of rouge, and the effective component of ointment is by following Chinese medicine composition system : fructus cannabis 50g, 50 g of Cortex Magnoliae Officinalis, dried immature fruit of citron orange 25g, cassia seed 35g, aloe 50g, lotus leaf 65g, Fructus Crataegi 35g, rhizoma alismatis 25g, jade Rice must 65g, rhizoma atractylodis 25g, dried orange peel 35g, blood clam 35g, Radix Salviae Miltiorrhizae 35g, safflower 65g, luffa 65g, turmeric 25g, Radix Curcumae 25g, Cortex Phellodendri 35g, Asian puccoon 35g, asarum 35g, moxa 180g, rhizoma zingiberis 60g, indigo naturalis 10g.

S1: prepare medicinal material according to above-mentioned parts by weight.

S2: Cortex Magnoliae Officinalis being set, ethanol in proper amount be added in stainless steel Chinese medicine extracting tank, 80 DEG C of extractions, extracts 2h, and filter is collected in filtration Liquid.Extract 2 times, merging filtrate, collect supernatant, and ethyl alcohol is recovered under reduced pressure, be concentrated into 1.05(40 DEG C of relative density) left and right Magma A.

S3: the blood clam that Cortex Magnoliae Officinalis, cassia seed and the gauze after corn stigma, lotus leaf, luffa, alcohol extracting wrap up is set stainless Suitable quantity of water is added in steel Chinese medicine extracting tank, 100 DEG C of heating, which decoct, extracts 1.5h, then safflower, the dried immature fruit of citron orange, the Beishan Mountain are added in extractor Short, bristly hair or beard, aloe, Radix Salviae Miltiorrhizae, 100 DEG C of fructus cannabis, rhizoma alismatis, rhizoma atractylodis, dried orange peel, Cortex Phellodendri, turmeric, Radix Curcumae heating, which decoct, extracts 1.5h, filtering, Collect filtrate.Extract 3 times, merging filtrate is concentrated into 1.08(40 DEG C of relative density) left and right magma B.

S4: the volatile oil of moxa, rhizoma zingiberis, asarum is extracted using SCF-CO 2 device, obtains Mixed chaotic sequences C.

S5: taking Asian puccoon to set in oil cauldron, and Oil-temperature control is 140 DEG C and fries to oil in aubergine, removes slag, filters, obtain filtrate D.

S6: taking above magma A, B to be uniformly mixed, and is put into after freezing in -20 DEG C of refrigerators and places into freeze drier and formed Powder is added 270mL purified water and dissolves to obtain medical fluid E.

S7: it takes indigo naturalis to be dissolved in 70mL dehydrated alcohol and obtains medical fluid F.

S8: medical fluid F and filtrate D being mixed and is filtered, and is stood 3h and is obtained medical fluid G.

S9: after will volatilize 4 times of ethyl alcohol dilution of oily C, glycerol, EDETATE DISODIUM, CMC-Na, PVPP, HQ841 water-setting is added The auxiliary materials such as gum cosmetics, Dihydroxyaluminium Aminoacetate, stir evenly；Then solution G is added to mix, adds solution E and PVPK120, oxybenzene second Hydrogel semisolid ointment is sufficiently stirred evenly to obtain after the auxiliary materials such as ester, 10% aqueous tartaric acid solution, menthol, borneol, 95% ethyl alcohol.

S10: semisolid ointment is coated on the base materials such as non-woven fabrics, hydrogel patch is obtained.After removal moisture drying, sealing Pack to obtain Chinese medicine external hydrogel emplastrum.

Embodiment 3

A kind for the treatment of subtracts tripe and disappears the Chinese medicine hydrogel emplastrum of rouge, and the effective component of ointment is by following Chinese medicine composition system : fructus cannabis 70g, Cortex Magnoliae Officinalis 70g, dried immature fruit of citron orange 35g, cassia seed 55g, aloe 70g, lotus leaf 90g, 55 parts of Fructus Crataegi, rhizoma alismatis 35g, jade Rice must 90g, rhizoma atractylodis 35g, dried orange peel 55g, blood clam 55g, Radix Salviae Miltiorrhizae 55g, safflower 90g, luffa 90g, turmeric 35g, Radix Curcumae 35g, Cortex Phellodendri 55g, Asian puccoon 55g, asarum 55g, moxa 250g, rhizoma zingiberis 110g, indigo naturalis 20g.

S1: prepare medicinal material according to above-mentioned parts by weight.

S2: Cortex Magnoliae Officinalis being set, ethanol in proper amount be added in stainless steel Chinese medicine extracting tank, and 75 DEG C of extractions are extracted 1.5h, filtered, collect Filtrate.Extract 2 times, merging filtrate, collect supernatant, and ethyl alcohol is recovered under reduced pressure, be concentrated into 1.06(40 DEG C of relative density) left and right Magma A.

S3: the blood clam that Cortex Magnoliae Officinalis, cassia seed and the gauze after corn stigma, lotus leaf, luffa, alcohol extracting wrap up is set stainless Water is added in steel Chinese medicine extracting tank, 110 DEG C of heating, which decoct, extracts 1h, then safflower, the dried immature fruit of citron orange, Fructus Crataegi, reed are added into extractor Luxuriant growth, Radix Salviae Miltiorrhizae, fructus cannabis, rhizoma alismatis, rhizoma atractylodis, dried orange peel, Cortex Phellodendri, turmeric, Radix Curcumae are heated to 110 DEG C, decoct and extract 1h, filter is collected by filtration Liquid.Extract 2 times, merging filtrate is concentrated into 1.13(40 DEG C of relative density) left and right magma B.

S4: first spraying cellulase solution for moxa, rhizoma zingiberis, asarum, ferments 3 days in 50 DEG C, the raw material after fermentation is added 60% ethyl alcohol for entering 6 times of weight, using continuous flow upstream ultrasonic extraction, then through petroleum ether extraction 2 times to get Mixed chaotic sequences C.

S5: taking Asian puccoon to set in oil cauldron, and Oil-temperature control is 150 DEG C and fries to oil in aubergine, removes slag, filters, obtains filtrate D.

S6: taking above magma A, B to be uniformly mixed, and is put into after freezing in -20 DEG C of refrigerators and places into freeze drier and formed Powder is added and dissolves to obtain medical fluid E with 330mL purified water.

S7: it takes indigo naturalis to be dissolved in 130mL dehydrated alcohol and obtains medical fluid F.

S9: will volatilize oily C with ethyl alcohol dilute 4 times, be added glycerol, propylene glycol, EDETATE DISODIUM, CMC-Na, PVPP, The polyacrylic acid that the part HQ800(neutralizes) after the auxiliary materials such as hydrogel resin powder, Dihydroxyaluminium Aminoacetate, stirs evenly, it is mixed to add medical fluid G It is even, add medical fluid E and PVPK120, ethyl hydroxy benzoate, 10% aqueous tartaric acid solution, menthol, borneol, 95% ethyl alcohol, etc. after auxiliary materials Sufficiently stir evenly to obtain hydrogel semisolid ointment.

S10: semisolid ointment is coated on base material, and hydrogel patch is made.After removal moisture drying, sealed package is obtained Chinese medicine external hydrogel emplastrum.

Embodiment 4

A kind for the treatment of subtracts tripe and disappears the Chinese medicine hydrogel emplastrum of rouge, and the effective component of ointment is by following Chinese medicine composition system : fructus cannabis 55g, 55 g of Cortex Magnoliae Officinalis, dried immature fruit of citron orange 30g, cassia seed 45g, aloe 60g, lotus leaf 75g, Fructus Crataegi 45g, rhizoma alismatis 30g, jade Rice must 75g, rhizoma atractylodis 30g, dried orange peel 45g, blood clam 45g, Radix Salviae Miltiorrhizae 45g, safflower 75g, luffa 75g, turmeric 30g, Radix Curcumae 30g, Cortex Phellodendri 45g, Asian puccoon 45g, asarum 45g, moxa 220g, rhizoma zingiberis 80g, indigo naturalis 14g.

S1: prepare medicinal material according to above-mentioned parts by weight；

S2: Cortex Magnoliae Officinalis being set, ethanol in proper amount be added in stainless steel Chinese medicine extracting tank, and 90 DEG C of extractions are extracted 1.5h, filtered, collect Filtrate.Extract 2 times, merging filtrate, collect supernatant, and ethyl alcohol is recovered under reduced pressure, be concentrated into 1.07(40 DEG C of relative density) left and right Magma A.

S4: moxa, rhizoma zingiberis, asarum are put into light oil extractor using extraction by steam distillation 5 hours；

Embodiment 5

S1: prepare medicinal material according to above-mentioned parts by weight；

S4: moxa, rhizoma zingiberis, asarum are put into light oil extractor using extraction by steam distillation 6 hours；

Embodiment 6

S1: prepare medicinal material according to above-mentioned parts by weight；

S4: first spraying cellulase solution for moxa, rhizoma zingiberis, asarum, ferments 8 days in 40 DEG C, the raw material after fermentation is added 50% ethyl alcohol for entering 4 times of weight, using continuous flow upstream ultrasonic extraction, then through petroleum ether extraction 2 times to get Mixed chaotic sequences C；

Embodiment 7

S1: prepare medicinal material according to above-mentioned weight；

S4: first spraying cellulase solution for moxa, rhizoma zingiberis, asarum, ferments 5 days in 45 DEG C, the raw material after fermentation is added 55% ethyl alcohol for entering 5 times of weight extracts 3 times using continuous flow upstream ultrasonic extraction, then through ether to get Mixed chaotic sequences C；

S9: after will volatilize 4 times of ethyl alcohol dilution of oily C, glycerol, EDETATE DISODIUM, CMC-Na, PVPP, HQ841 water-setting is added The auxiliary materials such as gum cosmetics, Dihydroxyaluminium Aminoacetate, stir evenly；Then solution G is added to mix, adds solution E and PVPK120, oxybenzene second Hydrogel semisolid ointment is sufficiently stirred evenly to obtain after the auxiliary materials such as ester, 10% aqueous tartaric acid solution, menthol, borneol, 95% ethyl alcohol；

Clinical test:

1, trial state

Choose 60 lists of the outpatient service of affiliated hospital, Jiangxi University of Traditional Chinese Medicine and inpatient department's standard compliant age at 18-48 years old Pure property obesity patient, is made emplastrum with the prescription of embodiment 1.

All there is body obesity in all cases, abdominal circumference is uncoordinated, abdominal fat accumulation is serious.In conjunction with doctor trained in Western medicine to every patient Weight, the testing result of abdominal circumference, BMI, the Chinese Adult promulgated according in April, 2003 ministry of Health of China Department of Disease Control is super Weight and obesity prevention and control guide (trial regulation): BMI >=24 are that Chinese Adult is overweight；BMI >=28 are obesity；Male's waistline >=85cm, women waistline >=80cm are abdominal fat accumulation.Judge accordingly, observation object meet as defined in be included in standard.

Exclusion criteria: 1. Secondary Obesities as caused by other reasons: adrenocortical hyperfunction, thyroid function Decline the diseases such as disease, nanosom disease, hypogonadism and drug induced obesity；

2. being associated with the internal organs such as the serious heart, liver, kidney illness or hematological system disease patient；

3. cannot adhere to treating or the person that is unable to partner treatment；

4. lactation or pregnancy women, mental patient.

2, treatment method

Disappear that (weight of every aqueous gel emplastrum is for 1 times/day of the Chinese medicine hydrogel emplastrum of rouge using the of the invention tripe that subtracts 20g, application are having a size of 19cm*15cm), application time is 8h or more.10 days as a treatment course of continuous use.Between each course for the treatment of Stopping three days, and sufferer deactivates other drug (medicines such as orlistat, melbine for weight-reducing during treatment Object；Other drug sufferers for daily treating the illnesss such as hypertension do not deactivate), female patient menstruation a few days ago day and the moon Stop sticking Chinese medicine hydrogel emplastrum through period.Each patient at least uses two courses for the treatment of or more.

3, criterion of therapeutical effect

The simple obesity that the 5th obesity research academic conference in the whole nation held referring to 1997 in Beijing is revised Efficacy assessment standard is drafted as follows:

The testing result of the pretherapy and post-treatment weight of every patient, abdominal circumference, BMI are compared, it is effective: weight loss 5kg Above or BMI declines >=4；It is effective: weight loss 2~5kg or BMI decline 2~4；It is invalid: weight loss < 2kg or BMI decline < 2.

4, result

In 60 Simple Obesity Patients of investigation, using 2 ~ 4 courses for the treatment of of emplastrum of the invention, wherein effective patient 2, having the responder that clearly weight loss, abdominal circumference reduce is 50, and patient is using weight after emplastrum and abdominal circumference without obvious Variation has 8.Emplastrum is 86.7% to the total effective rate of Simple Obesity Patient.

5, typical case

Case 1: Nanchang City, Jiangxi Province people Wu, female, 24 years old, because of obese, waistline was bigger than normal, and aspiration participates in experience and " subtracts Tripe hydrogel plaster " clinical test.

Patient's (private prosecution) is fond of the higher object of the sugars such as cake dessert, candy usually, and BMI, which is greater than 24, to be had 2 years, usually sitting And it is few take exercise, therefore lead to obese, the symptoms such as waistline is bigger than normal.

Existing symptoms include patient mental is fine, and body obesity, waistline is bigger than normal, measures height 155cm, weight 58.5Kg, waistline 88cm, BMI=24.3, receive can, night sleeps peace, and two just put down, and pale tongue with white fur is slightly thick, and arteries and veins is slow；Past medical history, family history be such as: the past body State health, no other diseases history, no family's heredity medication history, addition diagnosis: simple obesity.

Specific treatment method: it in the first time course for the treatment of, advises patient to apply daily and subtracts tripe hydrogel plaster and continue 8h in SHENQUE acupoint, such as 4h is changed to if there is application time phenomena such as rubescent, itch.Patient is advised to do more physical exercises, few sitting, suitable control diet is kept away as far as possible Exempt from the pungent greasy, foods such as sugar content is higher.Present case uses the prescription of embodiment 1.

After 10 days courses for the treatment of, patient tells that belly has slight thermal sensation, and the duration is about when just starting application for the first time 15min, and after application 2h, more anxious defecation sense.Still there is slight thermal sensation when just application daily later, has after application 4h relatively anxious Defecation consciousness.During course for the treatment of use, without allergic phenomenas such as rubescent, itch, daily defecation rule is morning excretion, and stomach Intestines emptying ability is stronger, and feces volume is more, and excreta is normal.Patient pays attention to keeping on a diet, appropriate after meal to take a walk.Final patient tells Effectively, 2 Kg of weight loss to 56.5 Kg, waistline reduces 4 centimetres for experience, drops to 84cm, BMI=23.5.

In second of course for the treatment of, patient is advised to continue to implement to be told that daily application subtracts tripe hydrogel plaster in Shenque such as the first time course for the treatment of Cave continues 8h, is careful in one's diet.After 10 days courses for the treatment of, as identical in told in the first time course for the treatment of, belly has the slight heat of about 15min Sense, no allergic phenomena, daily defecation rule, is morning excretion, and gastrointestinal emptying ability is stronger, feces volume is more.Patient's note Meaning is kept on a diet, appropriate after meal to take a walk.Patient's weight reduces 2Kg to 54.5 Kg, and waistline reduces 4 centimetres, drops to 80cm, BMI =22.6。

Case 2: Nanchang City, Jiangxi Province people Ouyang, female, 23 years old, because of obese, waistline was bigger than normal, and aspiration participates in experience " subtracting tripe hydrogel plaster " clinical test.Present case uses the prescription of embodiment 1.

Patient's (private prosecution) is fond of the greasy object such as pungent, fried, sitting and few exercise usually, therefore leads to obese, The symptoms such as waistline is bigger than normal.

Existing symptoms include patient mental is fine, and body obesity, waistline is bigger than normal, measures height 152cm, 56 Kg of weight, waistline 87cm, BMI=24.2 of the patient, receive can, night sleeps peace, and two just put down, pink tongue, slightly indentation, and tongue fur is thin white, and arteries and veins moistens；Past medical history, Family history is such as: the past physical condition health, no other diseases history, no family's heredity medication history, addition diagnosis: simple obesity.

Specific treatment method: it in the first time course for the treatment of, advises patient to apply daily and subtracts tripe hydrogel plaster and continue 8h in SHENQUE acupoint, such as 4h is changed to if there is application time phenomena such as rubescent, itch.Patient is advised to do more physical exercises, few sitting, suitable control diet is kept away as far as possible Exempt from the pungent greasy, foods such as sugar content is higher.

After 10 days courses for the treatment of, patient tells that belly has slight thermal sensation, and the duration is about when just starting application for the first time 15min, and after application 3h, more anxious defecation sense.Still there is 15min slight thermal sensation when just application daily later, but without application 3h More anxious defecation consciousness afterwards.During course for the treatment of use, without allergic phenomenas such as rubescent, itch, and defecation frequency is compared to daily defecation Number increased, and ordinary circumstance is that daily morning defecation is primary, sometimes each defecation daily morning and evening, each gastrointestinal emptying ability Relatively strong, feces volume is more, and excreta is in black grease type.Patient diet is normal during sticking, and pays attention to no longer sitting.Patient tells Effectively, weight loss 1.5Kg to 54.5Kg, waistline reduces 3 centimetres for experience, drops to 84cm, BMI=23.6.

In second of course for the treatment of, patient is advised to continue to implement to be told that daily application subtracts tripe hydrogel plaster in Shenque such as the first time course for the treatment of Cave continues 8h, is careful in one's diet and moves.Patient diet is normal during sticking, and pays attention to no longer sitting.After 10 days courses for the treatment of, patient Tell as similar in told in the first time course for the treatment of, belly has the slight thermal sensation of about 15min, no allergic phenomena, but defecation frequency compared to first Secondary course for the treatment of rule, is that daily morning defecation is primary, and gastrointestinal emptying ability is stronger, and feces volume is more, and excreta is in black grease Class.Final patient tells experience effectively, and weight loss 2Kg to 52.5Kg, waistline reduces 4 centimetres, is down to 80cm, BMI=22.7.

The foregoing is merely curative effect preferred embodiment of the present invention, the equalization that all claims according to the present invention are done becomes Change modification, is all covered by the present invention.

Claims

1. a kind of disappear the Chinese medicine hydrogel emplastrum of rouge for subtracting tripe, include base material and the Chinese medicine for being attached to substrate material surface Ointment, it is characterised in that: the Chinese medicine composition is by as follows at being grouped as, according to the mass fraction, 50~70 parts of fructus cannabis, Cortex Magnoliae Officinalis 50~70 parts, 25~35 parts of the dried immature fruit of citron orange, 35~55 parts of cassia seed, 50~70 parts of aloe, 65~90 parts of lotus leaf, Fructus Crataegi 35~55 Part, 25~35 parts of rhizoma alismatis, 65~90 parts of corn stigma, 25~35 parts of rhizoma atractylodis, 35~55 parts of dried orange peel, 35~55 parts of blood clam, Radix Salviae Miltiorrhizae 35~55 parts, 65~90 parts of safflower, 65~90 parts of luffa, 25~35 parts of turmeric, 25~35 parts of Radix Curcumae, 35~55 parts of Cortex Phellodendri, 35~55 parts of Asian puccoon, 35~55 parts of asarum, 180~250 parts of moxa, 60~110 parts of rhizoma zingiberis and 10~20 parts of indigo naturalis.

A kind of disappear the Chinese medicine hydrogel emplastrum of rouge for subtracting tripe 2. according to claim 1, which is characterized in that the Chinese medicine Composition is 60 parts of fructus cannabis, 60 parts of Cortex Magnoliae Officinalis, 30 parts of the dried immature fruit of citron orange, 45 parts of cassia seed, 60 parts of aloe, lotus leaf 75 according to the mass fraction Part, 45 parts of Fructus Crataegi, 30 parts of rhizoma alismatis, 75 parts of corn stigma, 30 parts of rhizoma atractylodis, 45 parts of dried orange peel, 45 parts of blood clam, 45 parts of Radix Salviae Miltiorrhizae, safflower 75 parts, 75 parts of luffa, 30 parts of turmeric, 30 parts of Radix Curcumae, 45 parts of Cortex Phellodendri, 45 parts of Asian puccoon, 45 parts of asarum, 225 parts of moxa, rhizoma zingiberis 90 Part, 15 parts of indigo naturalis.

A kind of disappear the Chinese medicine hydrogel emplastrum of rouge for subtracting tripe 3. according to claim 1 or 2, which is characterized in that described Crude drug source in Chinese medicine composition meets following one or more of qualifications:

The Fructus Crataegi originates from Shandong；

The dried orange peel originates from Guangdong；

The safflower originates from Xinjiang；

The Asian puccoon originates from Xinjiang；

The dried immature fruit of citron orange originates from Jiangxi；

The lotus leaf originates from Jiangxi；

The asarum originates from Liaoning；

The rhizoma atractylodis originate from Liaoning；

The Cortex Phellodendri originates from Liaoning.

A kind of disappear the Chinese medicine hydrogel emplastrum of rouge for subtracting tripe 4. according to claim 1 or 2, which is characterized in that described In Chinese medicine composition, lotus leaf, corn stigma, safflower, luffa mass ratio be 1:1:1:1；The mass ratio of Asian puccoon and Cortex Phellodendri is 1: 1。

5. it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation method, it is characterised in that be following processing step:

S1: standby medicinal material: in parts by weight, 50~70 parts of fructus cannabis, 50~70 parts of Cortex Magnoliae Officinalis, 25~35 parts of the dried immature fruit of citron orange, Cassia are weighed Sub 35~55 parts, 50~70 parts of aloe, 65~90 parts of lotus leaf, 35~55 parts of Fructus Crataegi, 25~35 parts of rhizoma alismatis, corn stigma 65~90 Part, 25~35 parts of rhizoma atractylodis, 35~55 parts of dried orange peel, 35~55 parts of blood clam, 35~55 parts of Radix Salviae Miltiorrhizae, 65~90 parts of safflower, luffa 65~90 parts, 25~35 parts of turmeric, 25~35 parts of Radix Curcumae, 35~55 parts of Cortex Phellodendri, 35~55 parts of Asian puccoon, 35~55 parts of asarum, Chinese mugwort 180~250 parts of suede, 60~110 parts of rhizoma zingiberis and 10~20 parts of indigo naturalis；

S2: alcohol extracting: Cortex Magnoliae Officinalis investment being filled in the tank of ethyl alcohol, 1 ~ 2h of heating extraction, filtering, collection and merging filtrate, in collection Clear liquid is evaporated under reduced pressure recycling ethyl alcohol, is concentrated into the magma A of relative density 1.05~1.20；

S3: water mentions: by the blood clam investment Sheng of Cortex Magnoliae Officinalis, cassia seed and gauze package after corn stigma, lotus leaf, luffa, alcohol extracting Having in the tank of water, heating, which decocts, extracts 1 ~ 2h, then the addition safflower, the dried immature fruit of citron orange, Fructus Crataegi, aloe, Radix Salviae Miltiorrhizae into tank, fructus cannabis, Rhizoma alismatis, rhizoma atractylodis, dried orange peel, Cortex Phellodendri, turmeric and Radix Curcumae, heating, which decocts, extracts 1~2h, and merging filtrate is collected in filtering, is evaporated under reduced pressure dense Contracting obtains the magma B that relative density is 1.05 ~ 1.20；

S5: Asian puccoon is set and is fried in oil cauldron to oil in aubergine, is removed slag, filters, obtains filtered fluid D；

S6: magma A, magma B are mixed and is freeze-dried, is milled to powder, distilled water is added to dissolve to obtain medical fluid E;

S7: indigo naturalis is dissolved in ethyl alcohol and obtains solution F；

S9: will volatilize oil mixture C and diluted with ethyl alcohol, and auxiliary materials and mixing is added and stirs evenly again with medical fluid G, adds medical fluid later E and auxiliary material are sufficiently stirred to obtain hydrogel semisolid ointment；The accessory package aqueous gel auxiliary material；

6. it is according to claim 5 it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation method, feature exists In in step s 2, it is 60 ~ 90 DEG C that the alcohol extracting heating, which decocts temperature, and under conditions of vacuum tightness, refluxing extraction, often Secondary 1 ~ 2h of refluxing extraction is extracted 2 ~ 3 times in total, is merged each secondary filtrate after having extracted, is collected supernatant.

7. it is according to claim 5 it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation method, feature exists In, in step s3, it is 80 ~ 110 DEG C that the heating that the water mentions, which decocts temperature, under conditions of closed, extract 2 ~ 3 times in total, It decocts every time and extracts 1 ~ 2h, merge each secondary filtrate after having extracted.

8. it is according to claim 5 it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation method, feature exists In, in step s 4, it is described extract moxa, rhizoma zingiberis, Herba Asari volatile oil method be: moxa, rhizoma zingiberis, asarum are put into light oil and mentioned It takes in device, using 5~9h of extraction by steam distillation；Or it is extracted using SCF-CO 2 device；Or first use cellulase Processing is fermented 3 ~ 8 days in 40 ~ 50 DEG C, and the raw material after fermentation is added to 50 ~ 60% ethyl alcohol of 4 ~ 6 times of weight, using continuous inverse Ultrasonic extraction is flowed, then extracts 2 ~ 3 times through petroleum ether or ether to get volatile oil.

9. it is according to claim 5 it is a kind of for subtract tripe disappear rouge Chinese medicine hydrogel emplastrum preparation method, feature exists In, in the S9, the auxiliary material be by HQ841 or HQ800 hydrogel resin powder and glycerol, CMC-Na, PVPP, Dihydroxyaluminium Aminoacetate, EDETATE DISODIUM, PVPK120,10% aqueous tartaric acid solution, NP-700, menthol, borneol, 95% ethyl alcohol, azone, DMDMH, the third two One or more of alcohol, ethyl hydroxy benzoate are mixed.