CN106344888A - Traditional Chinese medicine composition having functions of tonifying spleen and qi, as well as preparation method and application of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition having functions of tonifying spleen and qi, as well as preparation method and application of traditional Chinese medicine composition Download PDFInfo
- Publication number
- CN106344888A CN106344888A CN201510426950.5A CN201510426950A CN106344888A CN 106344888 A CN106344888 A CN 106344888A CN 201510426950 A CN201510426950 A CN 201510426950A CN 106344888 A CN106344888 A CN 106344888A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- spleen
- medicine composition
- invigorating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine composition having the functions of tonifying spleen and qi, as well as a preparation method and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following active ingredients according to parts by weight: 7-13 parts of ginseng, 7-13 parts of rhizoma atractylodis macrocephalae, 7-13 parts of poria cocos, 7-13 parts of liquorice, 7-13 parts of amomum kravanh, 7-13 parts of rhizoma cyperi, 7-13 parts of dried ginger, 7-13 parts of hawthorn, 7-13 parts of mangnolia officinalis, 7-13 parts of eupatorium, 7-13 parts of fructus amomi, 7-13 parts of coptis chinensis, and 7-13 parts of clove. The traditional Chinese medicine composition having the functions of tonifying spleen and qi has the effects of resolving dampness, promoting the circulation of qi, warming the middle-jiao, strengthening the spleen, warming the stomach, promoting digestion, eliminating dampness, promoting urination and eliminating cold to stop pain. Clinical verification shows that a user does not have drug dependence, and the traditional Chinese medicine composition has the advantages of good curative effect, safety and stability. The preparation process is simple, safe and sanitary. A massage cream prepared from the traditional Chinese medicine composition having the functions of tonifying spleen and qi and a matrix or a carrier is convenient to use, has a good curative effect, is safe and stable, is mild and non-irritant to the skin, and has no toxic or side effects.
Description
Technical field
The present invention relates to Chinese medicine external product field, more particularly to a kind of Chinese medicine group with invigorating the spleen and benefiting QI function
Compound and its preparation method and application.
Background technology
Spleen dependent territory in the five elements, belongs to extremely cloudy in the moon in organ yin-yang.The spleen has the function to transport and transform nutrients, blood of uniting, the lucid yang sending up,
Defeated cloth essence of water and grain, for " source of generating QI and blood ".After human body birth, each internal organs organ all relies on spleen institute
The essence of water and grain of metaplasia is foster to moisten, therefore spleen is called " the foundation of acquired constitution ", and it constitutes spleen with stomach, meat, lip, mouth etc.
System.Ferritic is insufficiency of the spleen or eating and drinking without temperance, emotional factors, maladjustment in work and rest, and medicine, food or Patients with Chronic Renal Disease are wet
Evil residence long, all can cause the function void of spleen to decline, the source of vital function is not enough.Spleen is to the digestion of food and absorption simultaneously
Play a very important role, therefore almost all of gastroenteropathy all may occur in which or with insufficiency of the spleen.
Nowadays, with the quickening of social rhythm, the diet of people, living habit and in the live and work
Various pressure so that taste are in long-term weak state, gastroenteropathy with many people.Doctor trained in Western medicine is only at present
It is administered according to clinical symptoms, the medicine of such as polyzyme tabletses, lactasinum etc improves digestive and absorptive functions, bismuth aluminate compound
Deng alleviation stomach pain, but all cure the symptoms, not the disease, fundamentally do not improve spleen and stomach function.And, often
Spleen reinforcing nourishing the stomach medicine mostly is oral prescription, and medicine by oral administration afterwards can be by the Digestive system in gastrointestinal disturbances road etc.
Effect slacken the efficacy of a drug, simultaneously can to gastrointestinal disturbances road produce stimulate, on the contrary, topical drug have easy to use,
Safe the advantages of.
Content of the invention
Based on this it is necessary to spleen and stomach function cannot be effectively improved and intestines and stomach is deposited for conventional oral drugs
The shortcomings of stimulation and less effective, provide a kind of Chinese medicine composition with invigorating the spleen and benefiting QI function and its system
Preparation Method and application.
An object of the present invention is to provide a kind of Chinese medicine composition with invigorating the spleen and benefiting QI function.
Specific technical scheme is as follows:
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition be by with
Lower raw material is extracted and is prepared from: Radix Ginseng 7-13 part, Rhizoma Atractylodis Macrocephalae 7-13 part, Poria 7-13 part, Radix Glycyrrhizae
7-13 part, Fructus Amomi Rotunduss 7-13 part, Rhizoma Cyperi 7-13 part, Rhizoma Zingiberiss 7-13 part, Fructus Crataegi 7-13 part, Cortex Magnoliae Officinalis 7-13 part,
Herba Eupatorii 7-13 part, Fructus Amomi 7-13 part, Rhizoma Coptidis 2-8 part, Flos Caryophylli 2-8 part；Wherein, the described Rhizoma Atractylodis Macrocephalae is to fry in vain
Art, described Rhizoma Cyperi is Rhizoma Cyperi (processed with vinegar).
Wherein in an embodiment, the active component of described Chinese medicine composition is to be carried by following raw material
Take and be prepared from: 9 parts of Radix Ginseng, 11 parts of the Rhizoma Atractylodis Macrocephalae, 11 parts of Poria, 11 parts of Radix Glycyrrhizae, 11 parts of Fructus Amomi Rotunduss, Rhizoma Cyperi
11 parts, 11 parts of Rhizoma Zingiberiss, 11 parts of Fructus Crataegi, 11 parts of Cortex Magnoliae Officinalis, 11 parts of Herba Eupatorii, 11 parts of Fructus Amomi, 5 parts of Rhizoma Coptidis,
5 parts of Flos Caryophylli.
The Chinese medicine composition with invigorating the spleen and benefiting QI function of the present invention, is according to Chinese medicine " monarch "
Theory, add Radix Ginseng, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Poria, Fructus Crataegi be monarch drug, there is invigorating the stomach and promoting digestion, spleen reinforcing row
Gas, eliminate dampness and have diuretic effect acts on；Interpolation Flos Caryophylli, Fructus Amomi Rotunduss, Rhizoma Cyperi, Rhizoma Zingiberiss, Cortex Magnoliae Officinalis, Herba Eupatorii, Fructus Amomi are ministerial drug,
There is removing dampness circulation of qi promoting, warming middle-JIAO and strengthening the spleen, stomach warming preventing or arresting vomiting, the effect of dispersing cold for relieving pain；Interpolation Rhizoma Coptidis are adjuvant drug, tool
There is to rush down clearly asthenic fire；Adding Radix Glycyrrhizae is to make medicine, has the increase property of medicine, drops hypotoxic effect.
The pharmacological action of each composition is as follows respectively:
Radix Ginseng: strongly invigorating primordial QI, veins takes off admittedly, invigorating the spleen to benefit the lung, blood-nourishing of promoting the production of body fluid, tranquilize the mind and promote the intelligence.For body void
It is intended to take off, cold weak pulse of limb, spleen eating less, the deficiency of the lung is breathed with cough, injury thirst, Heat Diabetes, deficiency of qi and blood, long
Disease is empty to win, insomnia of palpitating with fear, and sexual impotence official is cold.
The Rhizoma Atractylodis Macrocephalae (is fried): bitter, sweet, temperature.Returns spleen, stomach.Invigorating the spleen and benefiting QI, eliminate dampness and have diuretic effect.For insufficiency of the spleen food
Few, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, edema.
Poria: sweet, light, put down.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For
Edema oliguria, spleen eating less, have loose bowels in loose stool, irritability, insomnia of palpitating with fear.
Radix Glycyrrhizae: sweet, put down.GUIXIN, lung, spleen, stomach.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough,
Relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen,
Four limbs contraction, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Fructus Amomi Rotunduss: removing dampness circulation of qi promoting, warming middle-JIAO to arrest vomiting, appetite-stimulating indigestion-relieving.For turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia
From the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, dyspepsia.
Rhizoma Cyperi (vinegar): dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium,
Hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, gastral cavity abdomen painful abdominal mass is vexed, distension pain, menoxenia, closed dysmenorrhea.
Rhizoma Zingiberiss: warming spleen and stomach for dispelling cold, Back to Yang Tongmai, warming the lung to resolve fluid-retention.For coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities
Faint pulse, cold fluid-retention is breathed with cough.
Fructus Crataegi: sour, sweet, tepor.Returns spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, scattered stasis, change turbid lipid-loweringing.
For meat stagnation, gastral cavilty distension, diarrhea dysentery abdominal pain, confidant sting, obstruction of qi in the chest and cardialgia, hernia pain, high fat
Mass formed by blood stasis.
Cortex Magnoliae Officinalis: eliminating dampness dissolving phlegm, lower gas removes full.For in humidity hysteresis wound, gastral cavity ruffian is vomited and diarrhoea, stagnation of QI due to dyspepsia, abdominal distention
Constipation, phlegm and retained fluid is breathed with cough.
Herba Eupatorii: removing dampness by means of aromatics, appetizing of being amusing, deliver expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, ' in mouth
Sweet, halitosis, sialism, heat-damp in summer exterior syndrome, hygropyrexia, from the beginning of, asthenia of generating heat, uncomfortable in chest is not relaxed.
Fructus Amomi: dampness elimination appetizing, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity ruffian is not hungry, taste are empty
Cold, vomiting is had loose bowels, pregnancy reactionss, frequent fetal movement.
Rhizoma Coptidis: bitter, tremble with fear.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.
For damp and hot feeling of fullness, vomit acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, the heart
Throb with fear not peaceful, blood-head tells nosebleed, conjunctival congestion, toothache, quench one's thirst, carbuncle swells furunculosis；External treatment eczema, eczema, auditory meatus stream
Pus.
Flos Caryophylli: pungent, temperature.Returns spleen, stomach, lung, kidney channel.Warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.Empty for taste
Cold, singultuss are vomitted, lack of appetite and vomiting, trusted subordinate's crymodynia, impotence due to deficiency of the kidney.
It is a further object of the present invention to provide a kind of preparation side of the Chinese medicine composition with invigorating the spleen and benefiting QI function
Method.
Specific technical scheme is as follows:
A kind of preparation method of the Chinese medicine composition with invigorating the spleen and benefiting QI function, comprises the following steps: weigh institute
State raw material, the water of 3-10 times amount of the described raw material weight of addition or the ethanol solution that mass fraction is 35-65% enter
Row extracts 1-2 time, obtains described Chinese medicine composition after concentrating filter liquor；The method of described extraction is supersound extraction
Method or decoction extraction method or reflux extraction or permeating extraction.
Wherein in an embodiment, comprise the following steps: weigh described raw material, be ground into middle powder, add
Above-mentioned raw materials weight 8 times amount mass fraction is 65% ethanol solution, stirs, and places 5 hours, then
It is transferred in percolation filtration extraction pot, the mass fraction adding raw material weight 10 times amount is that 45% ethanol solution is carried out
Seepage pressure effects, percolation speed collects 1 liter of percolate per hour by every kilogram of raw material, after the completion of extraction, from oozing
Filter and reclaim ethanol in liquid, be further concentrated to medical material: the weight of concentrated solution ratio is for 1:0.5.
It is a further object of the present invention to provide a kind of above-mentioned Chinese medicine composition with invigorating the spleen and benefiting QI function is in preparation
There is the application in the topical drug of invigorating the spleen and benefiting QI function.
Specific technical scheme is as follows:
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function has the topical drug of invigorating the spleen and benefiting QI function in preparation
In application.
It is a further object of the present invention to provide a kind of massage cream with invigorating the spleen and benefiting QI function.
Specific technical scheme is as follows:
A kind of massage cream with invigorating the spleen and benefiting QI function, described massage cream is that have invigorating the spleen and benefiting QI function by above-mentioned
Chinese medicine composition and massage cream commonly use substrate or carrier and be prepared from, described massage cream commonly uses substrate or carrier
Including oils and fatss, emulsifying agent, water, preservative, chelating agen, suspending agent, wetting agent, conditioner, opacifier,
Excipient, isostearyl glyceryl pentaerythrityl ether and essence.
Wherein in an embodiment, the described Chinese medicine composition with invigorating the spleen and benefiting QI function is in described massage cream
In percetage by weight be 10.0-35.0%；Relative density at 55 DEG C -65 DEG C for the described Chinese medicine composition is
1.05-1.25.
Wherein in an embodiment, described massage cream is to be prepared from by the raw material of following percetage by weight:
Described Chinese medicine composition 10.0-30.0%, water 40.0-43.0%, chelating agen 0.08-1.5%, suspending agent 0.8-1.5%,
Wetting agent 10.0-14.0%, emulsifying agent 7.0-9.0%, conditioner 0.1-0.5%, opacifier 0.3-1.0%, figuration
Agent 3.5-6.5%, isostearyl glyceryl pentaerythrityl ether 7.0-12.0%, preservative 0.7-1.5%, essence 0-0.3%.
Wherein in an embodiment, described massage cream is to be prepared from by the raw material of following percetage by weight:
Chinese medicine composition described in 20.0%, 41.85% water, 0.1%edta disodium, 0.1% allantoin, 0.2% xanthan gum,
8.0% butanediol, 4.0%1,3 propylene glycol, 0.5% glycine betaine, 0.8% hydroxypropyl starch phosphate, 0.6% dioxy
Change titanium, 1.8% stereth -2,2.0% stereth -21,4.5% cetearyl alcohol, 5.0% glycerol is hard
Fat acid ester, 4.0% isopropyl myristate, 3.0% caprylic/capric triglyceride, 2.0% polydimethylsiloxane,
0.03% bisabolol, 0.02% tetrahydrochysene piperine, 0.2% pantothenylol, 0.6% phenoxyethanol/Sensiva SC50,
0.1% essence, 0.6% Methylisothiazolinone/chlorphenesin.
The Chinese medicine composition with invigorating the spleen and benefiting QI function provided by the present invention, is raw material using pure Chinese medicine, no
Containing antibiotic and hormone, the tcm theory compatibility according to " monarch " forms, and has removing dampness circulation of qi promoting, temperature
Middle spleen invigorating, invigorating the stomach and promoting digestion, effect of eliminate dampness and have diuretic effect, according to clinical verification, will not produce drug dependence, also have
Effective in cure good, safety and stability advantage.
The preparation method of the above-mentioned Chinese medicine composition with invigorating the spleen and benefiting QI function provided by the present invention, has work
Skill is simple, the advantage of safety and sanitation.
The above-mentioned Chinese medicine composition with invigorating the spleen and benefiting QI function and massage cream provided by the present invention commonly use substrate
Or the external massage cream that carrier is prepared from, easy to use, good effect, safety and stability, the gentle nothing to skin
Stimulate, have no toxic side effect.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1 has the Chinese medicine composition of invigorating the spleen and benefiting QI function
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition is by following
Raw material extract be prepared from: 13 parts of Radix Ginseng, 13 parts of the Rhizoma Atractylodis Macrocephalae, 13 parts of Poria, 13 parts of Radix Glycyrrhizae,
13 parts of Fructus Amomi Rotunduss, 13 parts of Rhizoma Cyperi, 13 parts of Rhizoma Zingiberiss, 13 parts of Fructus Crataegi, 13 parts of Cortex Magnoliae Officinalis, 13 parts of Herba Eupatorii, sand
13 parts of core, 8 parts of Rhizoma Coptidis, 8 parts of Flos Caryophylli.
The preparation method with the Chinese medicine composition of invigorating the spleen and benefiting QI function is:
Weigh the raw material of above-mentioned each weight portion, be ground into middle powder, be placed in reflux, extract, tank, add above-mentioned former
Material weight 6 times amount quality is 65% ethanol solution reflux, extract, 1 time, and extracting solution filters, and filtering residue adds
The mass fraction of 3 times amount of above-mentioned raw materials weight is 45% ethanol solution reflux, extract, 1 time, and extracting solution is filtered
Cross, merge filtrate twice, reclaim ethanol and be simultaneously concentrated into medical material: concentrated solution weight ratio for 1:0.5, obtains final product and has
The Chinese medicine composition of invigorating the spleen and benefiting QI function.
Embodiment 2 has the Chinese medicine composition of invigorating the spleen and benefiting QI function
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition is by following
Raw material is extracted and is prepared from: 9 parts of Radix Ginseng, 11 parts of the Rhizoma Atractylodis Macrocephalae, 11 parts of Poria, 11 parts of Radix Glycyrrhizae, bean
Cool 11 parts, 11 parts of Rhizoma Cyperi, 11 parts of Rhizoma Zingiberiss, 11 parts of Fructus Crataegi, 11 parts of Cortex Magnoliae Officinalis, 11 parts of Herba Eupatorii, Fructus Amomi
11 parts, 5 parts of Rhizoma Coptidis, 5 parts of Flos Caryophylli.
The preparation method with the Chinese medicine composition of invigorating the spleen and benefiting QI function is:
Weigh the raw material of above-mentioned each weight portion, pulverize, be sufficiently mixed, medicated powder is placed in extraction pot, add
Above-mentioned raw materials weight 6 times amount mass fraction is 55% ethanol solution supersound extraction 1 time, extracting solution low speed from
The heart, obtains centrifugal liquid 1 and medicinal residues 1, centrifugal liquid 1 high speed centrifugation again, obtains centrifugal liquid 2；Medicinal residues 1 add again
Enter the ethanol solution supersound extraction that raw material weight 4 times amount mass fraction is 35% 1 time, extracting solution low-speed centrifugal,
Obtain centrifugal liquid 3 and medicinal residues 2, it is abandoned by medicinal residues 2, centrifugal liquid 3 high speed centrifugation again, obtain centrifugal liquid 1, close
And centrifugal liquid 2 and centrifugal liquid 4, concentrating under reduced pressure (70 DEG C -75 DEG C, -0.08mpa～-0.1mpa), reclaim ethanol,
It is concentrated into medical material: concentrated solution weight, than for 1:0.5, obtains final product the Chinese medicine composition with invigorating the spleen and benefiting QI function.
Embodiment 3 has the Chinese medicine composition of invigorating the spleen and benefiting QI function
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition is by following
Raw material is extracted and is prepared from: 7 parts of Radix Ginseng, 7 parts of the Rhizoma Atractylodis Macrocephalae, 7 parts of Poria, 7 parts of Radix Glycyrrhizae, Fructus Amomi Rotunduss 7
Part, 7 parts of Rhizoma Cyperi, 7 parts of Rhizoma Zingiberiss, 7 parts of Fructus Crataegi, 7 parts of Cortex Magnoliae Officinalis, 7 parts of Herba Eupatorii, 7 parts of Fructus Amomi, Rhizoma Coptidis 2
Part, 2 parts of Flos Caryophylli.
The preparation method with the Chinese medicine composition of invigorating the spleen and benefiting QI function is:
Weigh the raw material of above-mentioned each weight portion, be pulverized and mixed, add the decocting of above-mentioned raw materials weight 5 times amount to boil
Extract 2 times, extracting solution filters, and is concentrated into medical material: concentrated solution weight ratio for 1:0.5, obtains final product with spleen invigorating benefit
The Chinese medicine composition of airway dysfunction.
Embodiment 4 has the Chinese medicine composition of invigorating the spleen and benefiting QI function
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition is by following
Raw material is extracted and is prepared from: 9 parts of Radix Ginseng, 11 parts of the Rhizoma Atractylodis Macrocephalae, 11 parts of Poria, 11 parts of Radix Glycyrrhizae, bean
Cool 11 parts, 11 parts of Rhizoma Cyperi, 11 parts of Rhizoma Zingiberiss, 11 parts of Fructus Crataegi, 11 parts of Cortex Magnoliae Officinalis, 11 parts of Herba Eupatorii, Fructus Amomi
11 parts, 5 parts of Rhizoma Coptidis, 5 parts of Flos Caryophylli.
The preparation method with the Chinese medicine composition of invigorating the spleen and benefiting QI function is:
Weigh the raw material of above-mentioned each weight portion, be ground into middle powder, add above-mentioned raw materials weight 8 times amount quality to divide
The ethanol solution for 65% for the number, stirs, and places 5 hours, transfers in percolation filtration extraction pot, adds
Raw material weight 10 times amount mass fraction is that 45% ethanol solution carries out seepage pressure effects, and percolation speed presses every kilogram
1 liter of percolate collected per hour by raw material, after the completion of extraction, reclaims ethanol, be further concentrated to medicine from percolate
Material: the weight of concentrated solution, than for 1:0.5, obtains final product the Chinese medicine composition with invigorating the spleen and benefiting QI function.
Embodiment 5 has the Chinese medicine composition of invigorating the spleen and benefiting QI function
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition is by following
Raw material is extracted and is prepared from: 9 parts of Radix Ginseng, 11 parts of the Rhizoma Atractylodis Macrocephalae, 11 parts of Poria, 11 parts of Radix Glycyrrhizae, bean
Cool 11 parts, 11 parts of Rhizoma Cyperi, 11 parts of Rhizoma Zingiberiss, 11 parts of Fructus Crataegi, 11 parts of Cortex Magnoliae Officinalis, 11 parts of Herba Eupatorii, Fructus Amomi
11 parts, 5 parts of Rhizoma Coptidis, 5 parts of Flos Caryophylli.
The preparation method with the Chinese medicine composition of invigorating the spleen and benefiting QI function is:
Weigh the raw material of above-mentioned weight portion, be sufficiently mixed, be placed in extraction pot, add above-mentioned raw materials weight 7
The water reflux, extract, of times amount 2 times, 2 hours every time, collects volatile oil；Merging filtrate, filtrate filters, dense
It is reduced to medical material: the weight of concentrated solution, than for 1:0.5, obtains final product the Chinese medicine composition with invigorating the spleen and benefiting QI function.
Embodiment 6 has the Chinese medicine composition of invigorating the spleen and benefiting QI function
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition is by following
Raw material is extracted and is prepared from: 9 parts of Radix Ginseng, 11 parts of the Rhizoma Atractylodis Macrocephalae, 11 parts of Poria, 11 parts of Radix Glycyrrhizae, bean
Cool 11 parts, 11 parts of Rhizoma Cyperi, 11 parts of Rhizoma Zingiberiss, 11 parts of Fructus Crataegi, 11 parts of Cortex Magnoliae Officinalis, 11 parts of Herba Eupatorii, Fructus Amomi
11 parts, 5 parts of Rhizoma Coptidis, 5 parts of Flos Caryophylli.
The preparation method with the Chinese medicine composition of invigorating the spleen and benefiting QI function is:
Weigh the raw material of above-mentioned weight portion, be sufficiently mixed, be placed in extraction pot, addition weight is above-mentioned raw materials
6 times of mass fraction be 45% ethanol solution supersound extraction 2 times, medicinal liquid high speed centrifugation, reclaim ethanol
And it is concentrated into medical material: the weight of concentrated solution than for 1:0.5, that is, obtains the Chinese medicine composition with invigorating the spleen and benefiting QI function
Thing.
Embodiment 7 has the Chinese medicine composition of invigorating the spleen and benefiting QI function
A kind of Chinese medicine composition with invigorating the spleen and benefiting QI function, the active component of described Chinese medicine composition is by following
Raw material is extracted and is prepared from: 9 parts of Radix Ginseng, 11 parts of the Rhizoma Atractylodis Macrocephalae, 11 parts of Poria, 11 parts of Radix Glycyrrhizae, bean
Cool 11 parts, 11 parts of Rhizoma Cyperi, 11 parts of Rhizoma Zingiberiss, 11 parts of Fructus Crataegi, 11 parts of Cortex Magnoliae Officinalis, 11 parts of Herba Eupatorii, Fructus Amomi
11 parts, 5 parts of Rhizoma Coptidis, 5 parts of Flos Caryophylli.
The preparation method with the Chinese medicine composition of invigorating the spleen and benefiting QI function is:
Weigh the raw material of above-mentioned weight portion, be sufficiently mixed, be placed in extraction pot, add above-mentioned raw materials weight 4
55% ethanol solution reflux, extract, of times amount 2 times, 1.5 hours every time, filtrate filtered, and is concentrated into medical material: dense
The weight of contracting liquid, than for 1:0.5, obtains final product the Chinese medicine composition with invigorating the spleen and benefiting QI function.
Embodiment 8 has massage cream of invigorating the spleen and benefiting QI function and preparation method thereof
A kind of massage cream with invigorating the spleen and benefiting QI function, concrete raw material components and content are as shown in table 1.
Table 1 has massage cream raw material components and its percentage by weight of invigorating the spleen and benefiting QI function
The preparation method that this has the massage cream of invigorating the spleen and benefiting QI function comprises the following steps:
First, preposition process
(1) by a3 phase component manual mixing uniformly, cross colloid mill circulation and be milled to the full and uniform exquisiteness of powder body, stirring
State is down to 85 DEG C, standby；
(2) by d phase component stirring and dissolving to clear, standby；
(3) c phase component heated and stirred is dissolved to no granule clear shape, standby.
2nd, production technology
(1) a1 phase component is sequentially added emulsifying pot, open stirring (40r/min), be heated to 85 DEG C, fully stir
Mix to complete swelling；
(2) a2 phase component is added aqueous phase agitated kettle, be heated with stirring to 90 DEG C, insulation 20min sterilizing；
(3) b phase component is sequentially added oil phase agitated kettle, stirring (30r/min) state is heated to 85 DEG C, stirs
Mix dissolving to confirm, insulation 10min sterilizing；
(4) first aqueous phase pot component is filtered in (200 mesh sieve) suction emulsifying pot, confirm that dispersed with stirring uniformly, is stirred
Mix and continue under (40r/min) slowly b phase component to be filtered (200 mesh sieve) suction, pre-emulsification 5min, protect
Hold vacuum (- 0.02～-0.04mpa), high speed homogenization 10min, open emulsifying pot cover, add preposition process a3 phase
Component, continues high speed homogenization 15min, maintains stirring (40r/min), and temperature often reduces by 10 DEG C, opens homogenizer
High speed homogenization 2min, and open cooling water start lower the temperature；
(5) it is cooled to 60 DEG C, c, d phase component is slowly added to emulsifying pot successively, stir (40r/min), keep
Vacuum (- 0.04～-0.06mpa), high speed homogenization 2min, continues stirring cooling；
(6) it is cooled to 50 DEG C, e phase component is sequentially added emulsifying pot, stir (35r/min), high speed homogenization 2min,
Keep vacuum (- 0.04～-0.06mpa), close cooling water, continue stirring and be cooled to 40 DEG C, stop stirring, take
Sample detection ph value (4.0-6.0), qualified after obtain final product the massage cream with invigorating the spleen and benefiting QI function.
Embodiment 9 has the stability test of the massage cream of invigorating the spleen and benefiting QI function
There is the massage cream of invigorating the spleen and benefiting QI function respectively 40 DEG C (heat-resisting) by prepare in embodiment 8
Deposit 30 days with -10 DEG C (resisting cold), observed result shows, the massage cream with invigorating the spleen and benefiting QI function is no layered
With thinning trend phenomenon, illustrate that the massage cream with invigorating the spleen and benefiting QI function of embodiment 8 has good stablizing
Performance.
Embodiment 10 has the heavy metal analysis test of the massage cream of invigorating the spleen and benefiting QI function
Entrust China Guangzhou Analysis ＆. Test Center, what embodiment 8 prepared has invigorating the spleen and benefiting QI function
In massage cream, the content of heavy metal is detected, testing result is as shown in table 2.
Table 2 has the content of heavy metal in the massage cream of invigorating the spleen and benefiting QI function
| Analysis project | Inspection result | Measurement unit |
| Hydrargyrum | < 1 (qualified) | mg/kg |
| Lead | < 10 (qualified) | mg/kg |
| Arsenic | < 1 (qualified) | mg/kg |
| Cadmium | < 2 (qualified) | mg/kg |
The massage cream weight with invigorating the spleen and benefiting QI function of present invention offer is provided by test data in table 2
Metal detection result is qualified, has the advantages that safe and free of toxic and side effects.
Embodiment 11 has the irritation test of the massage cream of invigorating the spleen and benefiting QI function
By contrast experiment, that studies embodiment 8 preparation has the massage cream of invigorating the spleen and benefiting QI function to family's rabbit
The zest of skin.
First, Experimental agents
Test group: the massage cream with invigorating the spleen and benefiting QI function of embodiment 8 preparation.
Matched group: smear substrate (i.e. its excess in addition to the Chinese medicine extract of invigorating the spleen and benefiting QI in embodiment 8
Matter, i.e. carrier).
2nd, method and result
Skin irritation test method and step are according to the skin irritation in " cosmetics health specification 2007 editions "
Property test method is carried out with step.Wherein, contrast using about consubstantiality itself, left side goes to hair-fields to smear enforcement
The massage cream with invigorating the spleen and benefiting QI function of example 8 preparation, right side goes to hair-fields to smear substrate as comparison.
Repeatedly irritation test result is as shown in table 3.
Table 3 has the massage cream of invigorating the spleen and benefiting QI function to rabbit multiple irritation test result
As can be seen from Table 3, embodiment 8 preparation have invigorating the spleen and benefiting QI function massage cream multiple to rabbit
In irritation test, every animal average integral is 0.46 daily, and stimulus intensity evaluation is respectively less than 0.5,
The Chinese medicine invigorating the spleen and benefiting QI massage cream nonirritant of embodiment 8 preparation for non-stimulated, is described, safe.
Embodiment 12 has the clinical trial of the massage cream of invigorating the spleen and benefiting QI function
First, subject enrollment standard:
(1) men and women does not limit, and cooperation product beta test requires；
(2) it is mainly shown as abdominal distention, loose stool, tired；
(3) energy compatibility test well, can keep good daily life system time and dietary habit in the trial employment period.
2nd, the test course for the treatment of, given the test agent, sample using method and the time
The test course for the treatment of: 2 weeks；
Test group: the massage cream with invigorating the spleen and benefiting QI function of embodiment 8 preparation, specification is every 3g；
Use time and method: use time is two weeks, each 1 time of daily morning, noon and afternoon.Sample massage is taken to smear
3-5 minute at WEIYU acupoint, PIYU acupoint, Shangwan point, ZHONGWAN acupoint, pylorus Xiawan point, SHENQUE acupoint.
Matched group: oral BUZHONG YIQI WAN.One time 1 bag, 2-3 time on the one.
4th, evaluation of clinical curative effect standard
With abdominal distention, loose stool is wholly absent, and tired obvious mitigates as effective；Abdominal distention, loose stool disappears substantially, tired
Weary make moderate progress as effective；Abdominal distention, loose stool, tired no improve, be invalid.
5th, result on trial analysis
Person on probation must not be less than 50 people.
A total of 68 people participate in the on probation of the massage cream with invigorating the spleen and benefiting QI function.It is randomly divided into two groups, every group
34 people.During two groups of subject's Evaluation products, the allergy such as skin pruritus, twinge, redness all do not occur
Phenomenon etc..After test terminates, test group 16 people's abdominal distention, loose stool is wholly absent, and tired obvious mitigation, is aobvious
Effect；12 people's abdominal distention, loose stool disappears substantially, tired makes moderate progress, for effective；6 people's abdominal distention, loose stool, tired
Weary no improve, be invalid；Matched group 14 people's abdominal distention, loose stool is wholly absent, and tired obvious mitigation, is effective；
8 people's abdominal distention, loose stool disappears substantially, tired makes moderate progress, for effective；12 people's abdominal distention, loose stool, tired nothing
Improve, be invalid；People has concrete outcome as shown in table 4.
Table 4 has the massage cream clinical test results of invigorating the spleen and benefiting QI function
| The course for the treatment of | Test group | Matched group |
| Effective | 16 | 14 |
| Effectively | 12 | 8 |
| Invalid | 6 | 12 |
| Effective percentage | 82.4% | 64.7% |
Be can be seen that by test data in table 4 on probation through by a definite date two weeks, there is invigorating the spleen and benefiting QI function
The effective percentage of massage cream has reached 82.4%, illustrates that what the present invention provided has the massage cream of invigorating the spleen and benefiting QI function not
Only easy to use, and there is good effect, the advantage of safety and stability, spleen and stomach function can be improved well.
Each technical characteristic of embodiment described above can arbitrarily be combined, for making description succinct, not right
The all possible combination of each technical characteristic in above-described embodiment is all described, as long as however, these skills
There is not contradiction in the combination of art feature, be all considered to be the scope of this specification record.
Embodiment described above only have expressed the several embodiments of the present invention, and its description is more concrete and detailed,
But can not therefore be construed as limiting the scope of the patent.It should be pointed out that for this area
For those of ordinary skill, without departing from the inventive concept of the premise, can also make and some deform and change
Enter, these broadly fall into protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be with appended power
Profit requires to be defined.
Claims (9)
1. a kind of Chinese medicine composition with invigorating the spleen and benefiting QI function is it is characterised in that described Chinese medicine composition
Active component is to be prepared from by following raw material: Radix Ginseng 7-13 part, Rhizoma Atractylodis Macrocephalae 7-13 part, Poria 7-13
Part, Radix Glycyrrhizae 7-13 part, Fructus Amomi Rotunduss 7-13 part, Rhizoma Cyperi 7-13 part, Rhizoma Zingiberiss 7-13 part, Fructus Crataegi 7-13 part, thickness
Plain 7-13 part, Herba Eupatorii 7-13 part, Fructus Amomi 7-13 part, Rhizoma Coptidis 2-8 part, Flos Caryophylli 2-8 part.
2. the Chinese medicine composition with invigorating the spleen and benefiting QI function according to claim 1 it is characterised in that
The active component of described Chinese medicine composition is to be prepared from by following raw material: 9 parts of Radix Ginseng, the Rhizoma Atractylodis Macrocephalae 11
Part, 11 parts of Poria, 11 parts of Radix Glycyrrhizae, 11 parts of Fructus Amomi Rotunduss, 11 parts of Rhizoma Cyperi, 11 parts of Rhizoma Zingiberiss, 11 parts of Fructus Crataegi,
11 parts of Cortex Magnoliae Officinalis, 11 parts of Herba Eupatorii, 11 parts of Fructus Amomi, 5 parts of Rhizoma Coptidis, 5 parts of Flos Caryophylli.
3. the preparation method of the Chinese medicine composition with invigorating the spleen and benefiting QI function described in any one of claim 1-2,
It is characterized in that, comprise the following steps: weigh described raw material, add the water of described raw material weight 3-10 times amount
Or the ethanol solution that mass fraction is 35-65% carries out extracting 1-2 time, after concentrating filter liquor, obtain described Chinese medicine
Compositionss；The method of described extraction is ultrasonic extraction or decocts extraction method or reflux extraction or seepage pressure effects
Method.
4. the preparation method of the Chinese medicine composition with invigorating the spleen and benefiting QI function according to claim 3, its
It is characterised by, comprises the following steps: weigh described raw material, add the quality of described raw material weight 8 times amount to divide
The ethanol solution for 65% for the number, stirs, and places 5 hours, transfers in percolation filtration extraction pot, adds
The mass fraction of described raw material weight 10 times amount is that 45% ethanol solution carries out seepage pressure effects, and percolation speed is pressed
1 liter of percolate collected per hour by every kilogram of raw material, after the completion of extraction, reclaims ethanol from percolate, denseer
It is reduced to medical material: the weight of concentrated solution is than for 1:0.5.
5. the Chinese medicine composition with invigorating the spleen and benefiting QI function described in any one of claim 1-2 has in preparation
Application in the Chinese medicine external product of invigorating the spleen and benefiting QI function.
6. a kind of massage cream with invigorating the spleen and benefiting QI function is it is characterised in that described massage cream is will by right
Ask described in any one of 1-2 there is the Chinese medicine composition of invigorating the spleen and benefiting QI function and substrate or carrier is prepared from.
7. the massage cream with invigorating the spleen and benefiting QI function according to claim 6 is it is characterised in that described
Having the Chinese medicine composition of the invigorating the spleen and benefiting QI function percetage by weight in described massage cream is 10.0-35.0%；Institute
Stating relative density at 55 DEG C -65 DEG C for the Chinese medicine composition is 1.05-1.25.
8. the massage cream with invigorating the spleen and benefiting QI function according to claim 7 is it is characterised in that described
Massage cream is to be prepared from by the raw material of following percetage by weight: described Chinese medicine composition 10.0-30.0%, water
40.0-43.0%, chelating agen 0.08-1.5%, suspending agent 0.8-1.5%, wetting agent 10.0-14.0%, emulsifying agent
7.0-9.0%, conditioner 0.1-0.5%, opacifier 0.3-1.0%, excipient 3.5-6.5%, isostearyl glyceryl pentaerythrityl ether 7.0-12.0%,
Preservative 0.7-1.5%, essence 0-0.3%.
9. the massage cream with invigorating the spleen and benefiting QI function according to claim 8 is it is characterised in that described
Massage cream is to be prepared from by the raw material of following percetage by weight: Chinese medicine composition described in 20.0%, 41.85% water,
0.1%edta disodium, 0.1% allantoin, 0.2% xanthan gum, 8.0% butanediol, 4.0%1,3 propylene glycol, 0.5%
Glycine betaine, 0.8% hydroxypropyl starch phosphate, 0.6% titanium dioxide, 1.8% stereth -2,2.0% is hard
Lipidol polyethers -21,4.5% cetearyl alcohol, 5.0% glyceryl stearate, 4.0% isopropyl myristate, 3.0%
Caprylic/capric triglyceride, 2.0% polydimethylsiloxane, 0.03% bisabolol, 0.02% tetrahydrochysene piperine,
0.2% pantothenylol, 0.6% phenoxyethanol/Sensiva SC50,0.1% essence, 0.6% Methylisothiazolinone/chlorobenzene
Sweet ether.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510426950.5A CN106344888B (en) | 2015-07-20 | 2015-07-20 | Chinese medicine composition and its preparation method and application with strengthening the spleen and replenishing qi function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510426950.5A CN106344888B (en) | 2015-07-20 | 2015-07-20 | Chinese medicine composition and its preparation method and application with strengthening the spleen and replenishing qi function |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106344888A true CN106344888A (en) | 2017-01-25 |
| CN106344888B CN106344888B (en) | 2019-10-08 |
Family
ID=57842667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510426950.5A Active CN106344888B (en) | 2015-07-20 | 2015-07-20 | Chinese medicine composition and its preparation method and application with strengthening the spleen and replenishing qi function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106344888B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108743706A (en) * | 2018-08-24 | 2018-11-06 | 红河哈尼族彝族自治州妇幼保健院 | A kind of child massage massage cream |
| CN115444859A (en) * | 2022-11-10 | 2022-12-09 | 吉林华康药业股份有限公司 | Medicinal composition for tonifying spleen and eliminating dampness and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1362247A (en) * | 2001-01-08 | 2002-08-07 | 杨孟君 | Nano stomach-nourishing medicine of Aucklandiae and Amino and its preparation |
| CN101129692A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating stomachache caused by deficiency-cold of middle-jiao energy |
| CN101274059A (en) * | 2008-04-22 | 2008-10-01 | 梁进 | Method for preparing black plaster |
| CN103301408A (en) * | 2013-06-28 | 2013-09-18 | 珠海圣原生物科技有限公司 | Traditional Chinese medicine extract and massage cream prepared from extract |
| CN103721158A (en) * | 2012-10-11 | 2014-04-16 | 王宪凯 | Traditional Chinese medicine pill for treatment of chronic gastritis |
-
2015
- 2015-07-20 CN CN201510426950.5A patent/CN106344888B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1362247A (en) * | 2001-01-08 | 2002-08-07 | 杨孟君 | Nano stomach-nourishing medicine of Aucklandiae and Amino and its preparation |
| CN101129692A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating stomachache caused by deficiency-cold of middle-jiao energy |
| CN101274059A (en) * | 2008-04-22 | 2008-10-01 | 梁进 | Method for preparing black plaster |
| CN103721158A (en) * | 2012-10-11 | 2014-04-16 | 王宪凯 | Traditional Chinese medicine pill for treatment of chronic gastritis |
| CN103301408A (en) * | 2013-06-28 | 2013-09-18 | 珠海圣原生物科技有限公司 | Traditional Chinese medicine extract and massage cream prepared from extract |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108743706A (en) * | 2018-08-24 | 2018-11-06 | 红河哈尼族彝族自治州妇幼保健院 | A kind of child massage massage cream |
| CN115444859A (en) * | 2022-11-10 | 2022-12-09 | 吉林华康药业股份有限公司 | Medicinal composition for tonifying spleen and eliminating dampness and application thereof |
| CN115444859B (en) * | 2022-11-10 | 2023-01-24 | 吉林华康药业股份有限公司 | Medicinal composition for invigorating spleen and eliminating dampness and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106344888B (en) | 2019-10-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102048933B (en) | Chinese medicinal composition for treating infantile diarrhea and preparation method thereof | |
| CN101972395B (en) | Calming and decompressing traditional Chinese medicine composition and preparation method thereof | |
| CN103099959B (en) | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof | |
| CN102100856A (en) | Nano traditional Chinese medicine for treating bronchial asthma and preparation technology | |
| CN102068707A (en) | Traditional Chinese medicine contrast medium adjuvant used for B ultrasonic and preparation method thereof | |
| CN103432475B (en) | Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof | |
| CN105194308A (en) | Health-preserving medicinal liquor and preparing method thereof | |
| CN103041262B (en) | Traditional Chinese medicine enema for curing chronic prostatitis and preparing method thereof | |
| CN104274754A (en) | Traditional Chinese medicine composition for treating infantile enuresis and preparation method of traditional Chinese medicine composition | |
| CN106344888B (en) | Chinese medicine composition and its preparation method and application with strengthening the spleen and replenishing qi function | |
| CN105435125A (en) | Chinese herbal medicine beneficial for upper gastrointestinal cancer postoperative rehabilitation | |
| CN104784245A (en) | Medicine for treating cervical cancer | |
| CN104644967A (en) | Pharmaceutical composition for treating I-type diabetes and application thereof | |
| CN104857377A (en) | Traditional Chinese medicine extract for improving fatty liver, preparation method of traditional Chinese medicine extract and massage cream | |
| CN106177540A (en) | A kind of Herba Taraxaci oral liquid of clearing away heat to alleviate pain and preparation method thereof | |
| CN102293883B (en) | Chinese medicinal composition for treating child acute upper respiratory tract infection, and preparation method and application thereof | |
| CN104367743A (en) | Traditional Chinese medicine composition for treating bacillary dysentery and preparation method of traditional Chinese medicine composition | |
| CN104352675A (en) | Traditional Chinese medicine oral decoction for treating paediatrical odontoprisis | |
| CN104353043A (en) | Traditional Chinese medicine composition for treating dawn diarrhea and preparation method thereof | |
| CN103520644B (en) | Traditional Chinese medicine composition used for treating phlegm stagnation type hyperlipidaemia and preparation method of composition | |
| CN114732882B (en) | Traditional Chinese medicine composition and preparation method and application thereof | |
| CN103285243B (en) | Granules for treating hyperglycemia | |
| CN109692324B (en) | It is a kind of to disappear the Chinese medicine hydrogel emplastrum and preparation method thereof of rouge for subtracting tripe | |
| CN101985027A (en) | Chinese herbal medicine for treating liver cirrhosis | |
| CN105998448A (en) | Method for preparing mulberry oral solution for improving immunity and oral solution prepared by same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |