CN1096295A - 新的苯并五元环衍生物、含有它们的药物组合物及其制备方法 - Google Patents

新的苯并五元环衍生物、含有它们的药物组合物及其制备方法 Download PDF

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Publication number
CN1096295A
CN1096295A CN93112986A CN93112986A CN1096295A CN 1096295 A CN1096295 A CN 1096295A CN 93112986 A CN93112986 A CN 93112986A CN 93112986 A CN93112986 A CN 93112986A CN 1096295 A CN1096295 A CN 1096295A
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CN
China
Prior art keywords
formula
oxygen
carbalkoxy
amino
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN93112986A
Other languages
English (en)
Chinese (zh)
Inventor
G·霍夫曼
L·多贝
J·费希尔
E·佩伦伊
E·艾兹尔
J·马图茨
K·萨格希
L·索波瑞伊
G·哈乔斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Chemical Works of Gedeon Richter Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemical Works of Gedeon Richter Ltd filed Critical Chemical Works of Gedeon Richter Ltd
Publication of CN1096295A publication Critical patent/CN1096295A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN93112986A 1992-12-23 1993-12-22 新的苯并五元环衍生物、含有它们的药物组合物及其制备方法 Pending CN1096295A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP9204112 1992-12-23
HU9204112A HU211212B (en) 1992-12-23 1992-12-23 Process to prepare novel benzofurane and indane derivs. and pharmaceutical compns. contg. the said compds.

Publications (1)

Publication Number Publication Date
CN1096295A true CN1096295A (zh) 1994-12-14

Family

ID=10982764

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93112986A Pending CN1096295A (zh) 1992-12-23 1993-12-22 新的苯并五元环衍生物、含有它们的药物组合物及其制备方法

Country Status (4)

Country Link
CN (1) CN1096295A (hu)
AU (1) AU5821694A (hu)
HU (1) HU211212B (hu)
WO (1) WO1994014788A1 (hu)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106117160A (zh) * 2016-08-26 2016-11-16 浙江野风药业股份有限公司 一种3‑[(2‑胍基‑4‑噻唑)甲基硫基]丙亚氨酸甲酯的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0530264B1 (en) * 1990-05-15 1996-10-23 E.I. Du Pont De Nemours And Company Arthropodicidal tetrahydropyridazines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106117160A (zh) * 2016-08-26 2016-11-16 浙江野风药业股份有限公司 一种3‑[(2‑胍基‑4‑噻唑)甲基硫基]丙亚氨酸甲酯的制备方法
CN106117160B (zh) * 2016-08-26 2019-02-05 浙江野风药业股份有限公司 一种3-[(2-胍基-4-噻唑)甲基硫基]丙亚氨酸甲酯的制备方法

Also Published As

Publication number Publication date
AU5821694A (en) 1994-07-19
WO1994014788A1 (en) 1994-07-07
HU9204112D0 (en) 1993-04-28
HU211212B (en) 1996-02-28

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C06 Publication
PB01 Publication
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication