CN109602870A - A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof - Google Patents

A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof Download PDF

Info

Publication number
CN109602870A
CN109602870A CN201910031904.3A CN201910031904A CN109602870A CN 109602870 A CN109602870 A CN 109602870A CN 201910031904 A CN201910031904 A CN 201910031904A CN 109602870 A CN109602870 A CN 109602870A
Authority
CN
China
Prior art keywords
parts
radix
chinese medicine
rhizoma
granule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910031904.3A
Other languages
Chinese (zh)
Inventor
黄仕营
殷彬燕
林锦德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Southern Medical University
Original Assignee
Southern Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Medical University filed Critical Southern Medical University
Priority to CN201910031904.3A priority Critical patent/CN109602870A/en
Publication of CN109602870A publication Critical patent/CN109602870A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The present invention relates to a kind of Chinese medicine compositions for treating cervical spondylosis, granule and preparation method thereof, belong to technical field of traditional Chinese medicines.Chinese medicine composition of the invention includes the component of following parts by weight: 10~30 parts of rhizoma cibotii, 5~15 parts of radix aconiti lateralis preparata, 30~80 parts of semen coicis, 10~40 parts of Radix Paeoniae Alba, 10~40 parts of Rhizoma Chuanxiong, 5~10 parts of safflower, 5~10 parts of Rhizoma Et Radix Notopterygii, 5~10 parts of Radix Angelicae Pubescentis, 5~10 parts of the root of Dahurain angelica, 10~30 parts of uncaria, 20~30 parts of Os Draconis, 20~30 parts of raw oyster, 10~20 parts of Semen Cuscutae, 30~70 parts of pueraria lobata, 10~30 parts of Radix Salviae Miltiorrhizae, 10~30 parts of Radix Astragali, 5~10 parts of Rhizoma Atractylodis Macrocephalae, 5~10 parts of Poria cocos, 5~10 parts of ramulus cinnamomi, 5~10 parts of rhizoma alismatis, 19~30 parts of cordate houttuynia.Chinese medicine composition of the invention has the effect of expelling wind and activating blood flow stagnation resolvation, treatment of arthritis and promoting collateral and channels relieves pain, and clinic is usually used in forehead and the nape of the neck aches, is cold, and headache, dizziness, disease of hand do not relax, the fat print with teeth of pale tongue, and veins string is various types of cervical spondylosiss of primary symptom;Chinese medicine composition total effective rate of the invention is higher than 90%, and good effect has no toxic side effect, wide market.

Description

A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine compositions for treating cervical spondylosis, granule and preparation method thereof, belong to traditional Chinese medicine technology Field.
Background technique
Cervical spondylosis refers to that (such as nerve root, vertebra are dynamic because intervertebral disc degradation and its secondary pathological change involve surrounding tissue Arteries and veins, spinal cord, sympathetic nerve etc.), there is a kind of disease of corresponding clinical symptoms and sign.Cervical spondylosis is with neck shoulder back pain, arm fiber crops Wood etc. are main clinical manifestation, seriously affect work, the studying and living of patient, endanger the physical and mental health of patient.In WHO group It knits in " the global ten big chronic diseases " of (WHO) announcement, cervical spondylosis comes second.Patient with cervical Spondylopathy is up to 9 in global more than 60 hundred million populations Hundred million, China reports that the disease incidence of the disease is 17.3% at present.
Development and living-pattern preservation with information-intensive society, teen-age cervical vertebra health status is not allowed to find pleasure in recent years It sees, the disease incidence of the young and middle-aged person's of bending over one's desk working cervical spondylosis is 19.22%, and 29.1% students in middle and primary schools are there are cervical vertebra exception, 15.1 There are cervical vertebra related symptoms by~58.7% students in middle and primary schools.In recent years, as student's school work is nervous, premature long-time bends over one's desk reading It writes, paint, using computer etc., in addition fault, accumulates over a long period, leading to neck shoulder muscular strain, cervical vertebra disfiguration, making green few Year, cervical spondylosis disease incidence was in rising trend, and the report in 14 years old or less children occurs for existing cervical spondylosis.Therefore, developing new has Good therapeutic effect, treatment cervical spondylosis with China's independent intellectual property right Chinese medicine there are huge market prospects.
It mainly includes non-operative treatment and operative treatment that western medicine, which treats cervical spondylosis, and most of patient is with non-operative treatment Based on, including drug therapy, physiotherapy, traction treatment etc., only small number of patients need to take operative treatment.Doctor trained in Western medicine is for neck The treatment of vertebra disease cervicodynia is short of effective means, main using oral anti-inflammation and analgesic drugs, physical therapy, traction, cervical vertebra braking and hand The processing such as art treatment, short term effect is fine, but side effect is bigger, and late result is indefinite.Traditional Chinese medicine is in anti-treating cervical spondylosis The unique curative effect of aspect in more than 2000 years medical literatures, has a large amount of effectively treatment case to record, unique herbal treatment is so far Clinically it is still the main path for obtaining preferable therapeutic effect, obtains the approval of society.
Summary of the invention
A kind of Chinese medicine for treating cervical spondylosis is provided it is an object of the invention to overcome above-mentioned the deficiencies in the prior art place Composition, granule and preparation method thereof.
To achieve the above object, the technical scheme adopted by the invention is as follows: a kind of Chinese medicine composition for treating cervical spondylosis, it is described Chinese medicine composition includes the component of following parts by weight: 10~30 parts of rhizoma cibotii, 5~15 parts of radix aconiti lateralis preparata, 30~80 parts of semen coicis, Radix Paeoniae Alba 10~40 parts, 10~40 parts of Rhizoma Chuanxiong, 5~10 parts of safflower, 5~10 parts of Rhizoma Et Radix Notopterygii, 5~10 parts of Radix Angelicae Pubescentis, 5~10 parts of the root of Dahurain angelica, uncaria 10 ~30 parts, 20~30 parts of Os Draconis, 20~30 parts of raw oyster, 10~20 parts of Semen Cuscutae, 30~70 parts of pueraria lobata, Radix Salviae Miltiorrhizae 10~30 Part, 10~30 parts of Radix Astragali, 5~10 parts of Rhizoma Atractylodis Macrocephalae, 5~10 parts of Poria cocos, 5~10 parts of ramulus cinnamomi, 5~10 parts of rhizoma alismatis, cordate houttuynia 19~30 Part.
The theoretical foundation of the traditional chinese medicine composition of the invention are as follows: the positive position for height of running all over the body at head solely emits the gas of chill, and " wind is kind Go and count change, easily attack positive position ", so " head is windy ", then how insufficient negative blood is for positive position, therefore " head is how empty ", and happiness anger troubled thoughts compassion is feared Brain of frightened seven feelings all for first mind, the uncomfortable then head gas blood stasis of seven feelings is stagnant, and Liver Channel enters top top, and gallbladder channel is go the rounds in the two sides of head, The stagnant then hemostasis pent-up of the gas stasis of blood of liver and gallbladder is in head, therefore " the more stasis of bloods in head ", with the passing of time headache, presss from both sides phlegm wet, and alliteration headache is such as wrapped up in, also more Conjunction wetting phase, therefore " how wet head is ".Therefore dispelled scattered exogenous wind with Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, the root of Dahurain angelica, uncaria, Os Draconis, wind in raw oyster tranquilizing and hyperactivity-subduing;River Rhizome of chuanxiong, safflower, Radix Salviae Miltiorrhizae, pueraria lobata, Radix Paeoniae Alba, ramulus cinnamomi promoting blood circulation, channels sootheing and network vessel quickening, and harmonizing yingfen and weifen;Semen coicis, Rhizoma Atractylodis Macrocephalae, Poria cocos, rhizoma alismatis Clearing damp, to dispel phlegm wet originally;Rhizoma cibotii, Semen Cuscutae kidney tonifying are superintended and directed by force, Radix Astragali QI invigorating;And interior strongly fragrant heresy, most Yi Huare, cordate houttuynia are clear Heat without injuring one's stomach, use without consuming negative blood, a medicine number by clearing damp, can help full function.
Chinese medicine composition of the invention is by inventor on the basis of many years clinical practice, and reasonable plus minus compatibility forms, by Pueraria lobota Root, radix aconiti lateralis preparata, Radix Paeoniae Alba, Rhizoma Chuanxiong, safflower, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, the root of Dahurain angelica, uncaria, Os Draconis, raw oyster, Semen Cuscutae, rhizoma cibotii, Radix Salviae Miltiorrhizae, The 19 taste medicine such as Radix Astragali, Rhizoma Atractylodis Macrocephalae, Poria cocos, ramulus cinnamomi, rhizoma alismatis composition has the effect of expelling wind and activating blood flow stagnation resolvation, treatment of arthritis and promoting collateral and channels relieves pain, clinical It is usually used in forehead and the nape of the neck aches, is cold, headache, dizziness, disease of hand does not relax, the fat print with teeth of pale tongue, and veins string is primary symptom Various types of cervical spondylosiss.
As the preferred embodiment of Chinese medicine composition of the present invention, the Chinese medicine composition includes following parts by weight Component: 30 parts of rhizoma cibotii, 10 parts of radix aconiti lateralis preparata, 70 parts of semen coicis, 30 parts of Radix Paeoniae Alba, 30 parts of Rhizoma Chuanxiong, 10 parts of safflower, 10 parts of Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis 10 parts, 10 parts of the root of Dahurain angelica, 30 parts of uncaria, 30 parts of Os Draconis, 30 parts of raw oyster, 20 parts of Semen Cuscutae, 70 parts of pueraria lobata, 30 parts of Radix Salviae Miltiorrhizae, Huang 30 parts of stilbene, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 10 parts of ramulus cinnamomi, 10 parts of rhizoma alismatis, 30 parts of cordate houttuynia.
Second aspect, the present invention provides the preparation methods of above-mentioned Chinese medicine composition, comprising the following steps: weighs according to the ratio Each component, mixed grinding are stirred evenly at fine powder to get Chinese medicine composition.
The third aspect, the present invention provides a kind of pharmaceutical preparation, the pharmaceutical preparation is by above-mentioned Chinese medicine composition and pharmacy Upper acceptable auxiliary material is made.
As the preferred embodiment of pharmaceutical preparation of the present invention, the dosage form of the pharmaceutical preparation be tablet, granule, Capsule, mixture, pill, dripping pill, solid dispersion or micro-capsule.
Fourth aspect, the present invention provides a kind of granule, the granule is by above-mentioned Chinese medicine composition and pharmaceutically may be used The auxiliary material of receiving is made.
Granule of the invention is soft granule, and content shows brown to sepia;Acrid flavour, slight bitter.It takes of the invention Granule, blood, urine, feces routine no abnormality seen in treatment and after treatment, has no damage to the heart, Liver and kidney function.
As the preferred embodiment of granule of the present invention, the Chinese medicine composition and pharmaceutically acceptable auxiliary material Weight part ratio be 1:1~10.
As the preferred embodiment of granule of the present invention, the pharmaceutically acceptable auxiliary material includes filler, The filler is at least one of mannitol, lactose, sucrose, cyclodextrin, starch.
As the preferred embodiment of granule of the present invention, the taking dose of the granule is a 15g, one day 3 times.
5th aspect, the present invention provides the preparation methods of above-mentioned granule, comprising the following steps:
(1) Chinese medicine composition is added water to cook, filtrate is concentrated, obtains medicinal extract;
(2) step (1) resulting medicinal extract is uniformly mixed with filler, particle is made, it is dry to get granule.
Compared with prior art, the invention has the benefit that Chinese medicine composition of the invention has expelling wind and activating blood flow stagnation resolvation, The effect for the treatment of of arthritis and promoting collateral and channels relieves pain, clinic is usually used in forehead and the nape of the neck aches, is cold, and headache, dizziness, disease of hand do not relax, tongue Light fat print with teeth, veins string are various types of cervical spondylosiss of primary symptom;Chinese medicine composition total effective rate of the invention is higher than 90%, treats It imitates, has no toxic side effect, wide market.
Specific embodiment
Purposes, technical schemes and advantages in order to better illustrate the present invention, below in conjunction with specific embodiment to the present invention It is described further.
Embodiment 1
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 30 parts of rhizoma cibotii, 10 parts of radix aconiti lateralis preparata, 70 parts of semen coicis, 30 parts of Radix Paeoniae Alba, 30 parts of Rhizoma Chuanxiong, safflower 10 Part, 10 parts of Rhizoma Et Radix Notopterygii, 10 parts of Radix Angelicae Pubescentis, 10 parts of the root of Dahurain angelica, 30 parts of uncaria, 30 parts of Os Draconis, 30 parts of raw oyster, 20 parts of Semen Cuscutae, pueraria lobata 70 parts, 30 parts of Radix Salviae Miltiorrhizae, 30 parts of Radix Astragali, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 10 parts of ramulus cinnamomi, 10 parts of rhizoma alismatis, 30 parts of cordate houttuynia.
Granule described in the present embodiment the preparation method comprises the following steps:
(1) Chinese medicine composition is added water to cook, filtrate is concentrated, obtains medicinal extract;
(2) step (1) resulting medicinal extract is uniformly mixed with filler, particle is made, it is dry to get granule, filling Agent is lactose, and the weight part ratio of Chinese medicine composition and lactose is 1:3.
Embodiment 2
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 10 parts of rhizoma cibotii, 15 parts of radix aconiti lateralis preparata, 80 parts of semen coicis, 40 parts of Radix Paeoniae Alba, 40 parts of Rhizoma Chuanxiong, safflower 5 Part, 5 parts of Rhizoma Et Radix Notopterygii, 5 parts of Radix Angelicae Pubescentis, 5 parts of the root of Dahurain angelica, 10 parts of uncaria, 20 parts of Os Draconis, 20 parts of raw oyster, 10 parts of Semen Cuscutae, pueraria lobata 30 Part, 30 parts of Radix Salviae Miltiorrhizae, 10 parts of Radix Astragali, 5 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of Poria cocos, 5 parts of ramulus cinnamomi, 5 parts of rhizoma alismatis, 19 parts of cordate houttuynia.
The preparation method is the same as that of Example 1 for granule described in the present embodiment.
Embodiment 3
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 30 parts of rhizoma cibotii, 5 parts of radix aconiti lateralis preparata, 30 parts of semen coicis, 10 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, safflower 10 Part, 10 parts of Rhizoma Et Radix Notopterygii, 10 parts of Radix Angelicae Pubescentis, 10 parts of the root of Dahurain angelica, 30 parts of uncaria, 30 parts of Os Draconis, 30 parts of raw oyster, 20 parts of Semen Cuscutae, pueraria lobata 70 parts, 10 parts of Radix Salviae Miltiorrhizae, 30 parts of Radix Astragali, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 10 parts of ramulus cinnamomi, 10 parts of rhizoma alismatis, 30 parts of cordate houttuynia.
The preparation method is the same as that of Example 1 for granule described in the present embodiment.
Embodiment 4
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 20 parts of rhizoma cibotii, 10 parts of radix aconiti lateralis preparata, 50 parts of semen coicis, 30 parts of Radix Paeoniae Alba, 30 parts of Rhizoma Chuanxiong, safflower 8 Part, 8 parts of Rhizoma Et Radix Notopterygii, 8 parts of Radix Angelicae Pubescentis, 8 parts of the root of Dahurain angelica, 20 parts of uncaria, 25 parts of Os Draconis, 25 parts of raw oyster, 15 parts of Semen Cuscutae, pueraria lobata 50 Part, 20 parts of Radix Salviae Miltiorrhizae, 20 parts of Radix Astragali, 8 parts of Rhizoma Atractylodis Macrocephalae, 8 parts of Poria cocos, 8 parts of ramulus cinnamomi, 8 parts of rhizoma alismatis, 25 parts of cordate houttuynia.
The preparation method is the same as that of Example 1 for granule described in the present embodiment.
Embodiment 5
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 15 parts of rhizoma cibotii, 8 parts of radix aconiti lateralis preparata, 60 parts of semen coicis, 30 parts of Radix Paeoniae Alba, 20 parts of Rhizoma Chuanxiong, 6 parts of safflower, 6 parts of Rhizoma Et Radix Notopterygii, 6 parts of Radix Angelicae Pubescentis, 6 parts of the root of Dahurain angelica, 15 parts of uncaria, 20 parts of Os Draconis, 30 parts of raw oyster, 10 parts of Semen Cuscutae, 60 parts of pueraria lobata, pellet Join 25 parts, 25 parts of Radix Astragali, 6 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of Poria cocos, 6 parts of ramulus cinnamomi, 6 parts of rhizoma alismatis, 20 parts of cordate houttuynia.
The preparation method is the same as that of Example 1 for granule described in the present embodiment.
Comparative example 1
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 30 parts of Radix Paeoniae Alba, 30 parts of Rhizoma Chuanxiong, 10 parts of safflower, 10 parts of Rhizoma Et Radix Notopterygii, 10 parts of Radix Angelicae Pubescentis, 10 parts of the root of Dahurain angelica, hook 30 parts of rattan, 30 parts of Os Draconis, 30 parts of raw oyster, 20 parts of Semen Cuscutae, 70 parts of pueraria lobata, 30 parts of Radix Salviae Miltiorrhizae, 30 parts of Radix Astragali, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 10 parts of ramulus cinnamomi, 10 parts of rhizoma alismatis, 30 parts of cordate houttuynia.
The preparation method is the same as that of Example 1 for granule described in the present embodiment.
Comparative example 2
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 50 parts of rhizoma cibotii, 2 parts of radix aconiti lateralis preparata, 70 parts of semen coicis, 30 parts of Radix Paeoniae Alba, 30 parts of Rhizoma Chuanxiong, safflower 10 Part, 15 parts of Rhizoma Et Radix Notopterygii, 10 parts of Radix Angelicae Pubescentis, 3 parts of the root of Dahurain angelica, 30 parts of uncaria, 30 parts of Os Draconis, 15 parts of raw oyster, 20 parts of Semen Cuscutae, pueraria lobata 70 Part, 30 parts of Radix Salviae Miltiorrhizae, 30 parts of Radix Astragali, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 10 parts of ramulus cinnamomi, 10 parts of rhizoma alismatis, 30 parts of cordate houttuynia.
The preparation method is the same as that of Example 1 for granule described in the present embodiment.
Comparative example 3
The present invention treats a kind of embodiment of the granule of cervical spondylosis, the Chinese medicine composition in granule described in the present embodiment Component comprising following parts by weight: 30 parts of rhizoma cibotii, 10 parts of radix aconiti lateralis preparata, 20 parts of semen coicis, 5 parts of Radix Paeoniae Alba, 50 parts of Rhizoma Chuanxiong, safflower 10 Part, 15 parts of Rhizoma Et Radix Notopterygii, 10 parts of Radix Angelicae Pubescentis, 15 parts of the root of Dahurain angelica, 30 parts of uncaria, 15 parts of Os Draconis, 30 parts of raw oyster, 20 parts of Semen Cuscutae, pueraria lobata 70 parts, 30 parts of Radix Salviae Miltiorrhizae, 30 parts of Radix Astragali, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 10 parts of ramulus cinnamomi, 10 parts of rhizoma alismatis, 30 parts of cordate houttuynia.
The preparation method is the same as that of Example 1 for granule described in the present embodiment.
The effect test of the Granules in Treating cervical spondylosis of the present invention of effect example 1
(1) clinical data
Clinical observation treatments are carried out to 800 patient with cervical Spondylopathy by screening, the age at 28~58 years old, male or female, with Patient is divided into 8 groups by machine, and every group of 100 people take the granule of the embodiment of the present invention 1~5, comparative example 1~3 respectively.
(2) curative effect determinate standard
Cure: Clinical symptom and sign disappears, and restores normal;
Effective: clinical symptoms are clearly better, and substantially or mostly disappear;
Invalid: Clinical symptom and sign is without improvement.
(3) treatment method
Take the granule of the embodiment of the present invention 1~5, comparative example 1~3, each 15g, 3 times a day, warm boiled water.
(4) therapeutic effect
Follow-up observation is carried out for 800 patients over the course for the treatment of, does not find apparent adverse reaction.Treatment results are such as Shown in table 1.
Table 1
It cures Effectively In vain
Embodiment 1 95 3 2
Embodiment 2 85 12 3
Embodiment 3 87 9 4
Embodiment 4 90 7 3
Embodiment 5 91 5 4
Comparative example 1 19 34 47
Comparative example 2 25 36 39
Comparative example 3 31 41 28
As shown in Table 1, the granule of the embodiment of the present invention 1~5 is taken, cure rate is up to 80% or more, and total effective rate is high Up to 90% or more.Chinese medicine composition in the granule of comparative example 1 is free of rhizoma cibotii, radix aconiti lateralis preparata, semen coicis, and effective percentage is obvious not Such as the present invention;The parts by weight of Chinese medicine composition in the granule of comparative example 2~3 are not complete within the scope of the present invention, efficient It is obvious to be not so good as the present invention.
As it can be seen that there is good curative effect to the quality of cervical spondylosis by component of the invention and the granule of proportion preparation.And And when rhizoma cibotii is 30 parts by weight, radix aconiti lateralis preparata is 10 parts by weight, semen coicis is 70 parts by weight, Radix Paeoniae Alba is 30 parts by weight, Rhizoma Chuanxiong 30 Parts by weight, safflower are 10 parts of weight, Rhizoma Et Radix Notopterygii is 10 parts by weight, Radix Angelicae Pubescentis is 10 parts by weight, the root of Dahurain angelica is 10 parts by weight, uncaria is 30 weights Measure part, Os Draconis is 30 parts by weight, raw oyster is 30 parts by weight, Semen Cuscutae is 20 parts by weight, pueraria lobata is 70 parts by weight, Radix Salviae Miltiorrhizae is 30 parts by weight, Radix Astragali are 30 parts by weight, Rhizoma Atractylodis Macrocephalae is 10 parts by weight, Poria cocos is 10 parts by weight, ramulus cinnamomi is 10 parts by weight, rhizoma alismatis 10 When parts by weight, cordate houttuynia are 30 parts by weight, granule obtained has the treatment optimal curative effect of cervical spondylosis.
The clinical case of the Granules in Treating cervical spondylosis of the present invention of effect example 2
Case 1
It is high certain, 35 years old, male suffered from cervical spondylosis for many years, and various western medicines, symptom does not subtract.Take particle provided by the invention Agent, each 15g, three times a day, after a week, pain subtracts greatly, continues to take one month, and symptom disappears, and functional rehabilitation is normal.
Case 2
Zhao, 52 years old, female, long-term cervical pain was tetanic, and neck is stiff, and it is unfavorable to change one's position, and arm is numb, and nuclear-magnetism checks spondylotic radiculopathy Cervical spondylosis, a variety of treatments are still without positive effect.Granule of the invention is taken, after two weeks, symptom arm is numb, neck of having a headache Tetanic disappearance.
Case 3
Qian, 52 years old, male, because neck aching of shoulder and arm, skin have numbness, allergy, left hand scratched side numbness distending pain, are diagnosed as nerve Root myelopathy.Granule of the invention is taken, has a headache and disappears after 20 days, Jingbi is ached disappearance after 1 month, nearly 3 months upper lefts Acroanesthesia disappears.No recurrence is visited after 1 year.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention And range.

Claims (10)

1. a kind of Chinese medicine composition for treating cervical spondylosis, which is characterized in that the Chinese medicine composition includes the group of following parts by weight Point: 10~30 parts of rhizoma cibotii, 5~15 parts of radix aconiti lateralis preparata, 30~80 parts of semen coicis, 10~40 parts of Radix Paeoniae Alba, 10~40 parts of Rhizoma Chuanxiong, safflower 5 ~10 parts, 5~10 parts of Rhizoma Et Radix Notopterygii, 5~10 parts of Radix Angelicae Pubescentis, 5~10 parts of the root of Dahurain angelica, 10~30 parts of uncaria, 20~30 parts of Os Draconis, raw oyster 20~30 parts, 10~20 parts of Semen Cuscutae, 30~70 parts of pueraria lobata, 10~30 parts of Radix Salviae Miltiorrhizae, 10~30 parts of Radix Astragali, 5~10 parts of Rhizoma Atractylodis Macrocephalae, Fu 5~10 parts of Siberian cocklebur, 5~10 parts of ramulus cinnamomi, 5~10 parts of rhizoma alismatis, 19~30 parts of cordate houttuynia.
2. Chinese medicine composition as described in claim 1, which is characterized in that the Chinese medicine composition includes the group of following parts by weight Point: 30 parts of rhizoma cibotii, 10 parts of radix aconiti lateralis preparata, 70 parts of semen coicis, 30 parts of Radix Paeoniae Alba, 30 parts of Rhizoma Chuanxiong, 10 parts of safflower, 10 parts of Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis 10 Part, 10 parts of the root of Dahurain angelica, 30 parts of uncaria, 30 parts of Os Draconis, 30 parts of raw oyster, 20 parts of Semen Cuscutae, 70 parts of pueraria lobata, 30 parts of Radix Salviae Miltiorrhizae, Radix Astragali 30 parts, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 10 parts of ramulus cinnamomi, 10 parts of rhizoma alismatis, 30 parts of cordate houttuynia.
3. such as the preparation method of the described in any item Chinese medicine compositions of claim 1~2, which comprises the following steps: Each component is weighed according to the ratio, and mixed grinding is stirred evenly at fine powder to get Chinese medicine composition.
4. a kind of pharmaceutical preparation, which is characterized in that the pharmaceutical preparation is by the described in any item Chinese traditional medicine compositions of claim 1~2 Object is made with pharmaceutically acceptable auxiliary material.
5. pharmaceutical preparation as claimed in claim 4, which is characterized in that the dosage form of the pharmaceutical preparation is tablet, granule, glue Wafer, mixture, pill, dripping pill, solid dispersion or micro-capsule.
6. a kind of granule, which is characterized in that the granule by the described in any item Chinese medicine compositions of claim 1~2 with Pharmaceutically acceptable auxiliary material is made.
7. granule as claimed in claim 6, which is characterized in that the Chinese medicine composition and pharmaceutically acceptable auxiliary material Weight part ratio is 1:1~10.
8. granule as claimed in claim 6, which is characterized in that the pharmaceutically acceptable auxiliary material includes filler, institute Stating filler is at least one of mannitol, lactose, sucrose, cyclodextrin, starch.
9. granule as claimed in claim 6, which is characterized in that the taking dose of the granule be a 15g, one day 3 It is secondary.
10. such as the preparation method of the described in any item granules of claim 6~9, which comprises the following steps:
(1) Chinese medicine composition is added water to cook, filtrate is concentrated, obtains medicinal extract;
(2) step (1) resulting medicinal extract is uniformly mixed with filler, particle is made, it is dry to get granule.
CN201910031904.3A 2019-01-14 2019-01-14 A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof Pending CN109602870A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910031904.3A CN109602870A (en) 2019-01-14 2019-01-14 A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910031904.3A CN109602870A (en) 2019-01-14 2019-01-14 A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof

Publications (1)

Publication Number Publication Date
CN109602870A true CN109602870A (en) 2019-04-12

Family

ID=66016770

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910031904.3A Pending CN109602870A (en) 2019-01-14 2019-01-14 A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof

Country Status (1)

Country Link
CN (1) CN109602870A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101015651A (en) * 2007-03-01 2007-08-15 陈守杰 Medicine for treating protrusion of lumbar intervertebral disc
KR20100042337A (en) * 2008-10-16 2010-04-26 변정윤 The composition of traditional oriental medicines for reheumatoid arthritis and the method of preparing medicine for it
CN104225128A (en) * 2014-09-03 2014-12-24 张士远 Pharmaceutical preparation for relieving headache caused by cervical spondylosis and preparation method of pharmaceutical preparation
CN108671203A (en) * 2018-07-30 2018-10-19 顾倪瑄 A kind of Chinese medicine for treating nerve root cervical vertebra sickness

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101015651A (en) * 2007-03-01 2007-08-15 陈守杰 Medicine for treating protrusion of lumbar intervertebral disc
KR20100042337A (en) * 2008-10-16 2010-04-26 변정윤 The composition of traditional oriental medicines for reheumatoid arthritis and the method of preparing medicine for it
CN104225128A (en) * 2014-09-03 2014-12-24 张士远 Pharmaceutical preparation for relieving headache caused by cervical spondylosis and preparation method of pharmaceutical preparation
CN108671203A (en) * 2018-07-30 2018-10-19 顾倪瑄 A kind of Chinese medicine for treating nerve root cervical vertebra sickness

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
国医编委会等: "《中医秘方妙用治百病》", 31 January 2016, 黑龙江科学技术出版社 *
韦桂宁等: "《小偏方胜名医 独特偏方祛百病》", 30 September 2015, 军事医学科学出版社 *

Similar Documents

Publication Publication Date Title
CN104491801A (en) Traditional Chinese medicine preparation for treating acute or chronic gastritis and preparation method thereof
CN101711847B (en) Oral traditional Chinese medicine preparation for treating melancholia and anxiety neurosis
CN102940851A (en) Traditional Chinese medicine dispersible tablet for cervical spondylosis and preparation method thereof
CN102600426B (en) Chinese medicinal preparation for promoting blood circulation to remove blood stasis and preparation method thereof
CN105582428A (en) Transdermal patch for acupoint sticking therapy and preparation method thereof
CN103330868B (en) Intestinal tract replenishing liquid for chronic renal failure
CN115252753B (en) Traditional Chinese medicine composition for treating insomnia and application thereof
CN104491802A (en) Application of traditional Chinese medicine preparation in preparation of medicine for treating acute or chronic gastritis
CN100371012C (en) Medicinal composition, and its preparing method and use
CN103301355A (en) Preparation method of chronic renal failure colon dialysate
CN102988887A (en) Chinese medicament for treating ovarian cyst
CN104666658A (en) Traditional Chinese medicine composition for treating osteosarcoma ostalgia and bone metastasis neoplasm ostalgia, and preparation method and application of traditional Chinese medicine composition
CN104435567A (en) Traditional Chinese medicinal composition containing gynostemma pentaphyllum for treating gout
CN104042981A (en) Medicament for treating postnatal constipation and preparation method thereof
CN104436121B (en) It is a kind of to treat irregular menstruation, small distention and fullness in the abdomen, the medicine to fail to be impregnated for a long time
CN100515462C (en) Chinese medicine for treating cardiovascular and cerebrovascular trrombus and preparing method
CN109602870A (en) A kind of Chinese medicine composition that treating cervical spondylosis, granule and preparation method thereof
CN1730093A (en) Chinese traditional medicine preparation for treating cancer and application thereof
CN105169279A (en) Traditional Chinese medicine composition for treating knee joint bone hyperplasia
CN103845690A (en) Medicament for treating geriatric depression
CN110841007B (en) Traditional Chinese medicine composition for treating cerebral apoplexy sequela and application thereof
CN115814020B (en) Traditional Chinese medicine composition for treating ventricular arrhythmia and application thereof
CN115624586B (en) Traditional Chinese medicine composition for treating hormone-dependent asthma and application thereof
CN102397368B (en) Chinese medicinal preparation for treating cyclomastopathy
CN102631618A (en) Traditional Chinese medicine for treating diabetes

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190412