CN109568452A - A kind of external medicine composition that treating gynaecological imflammation and its application - Google Patents

A kind of external medicine composition that treating gynaecological imflammation and its application Download PDF

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CN109568452A
CN109568452A CN201910059519.XA CN201910059519A CN109568452A CN 109568452 A CN109568452 A CN 109568452A CN 201910059519 A CN201910059519 A CN 201910059519A CN 109568452 A CN109568452 A CN 109568452A
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parts
flower
gynaecological imflammation
treatment
medicine composition
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张书翔
王东艳
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Beijing Pengye Shengshi Biotechnology Co Ltd
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Beijing Pengye Shengshi Biotechnology Co Ltd
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Abstract

The invention discloses a kind of external medicine composition for treating gynaecological imflammation and its applications, belong to technical field of traditional Chinese medicine preparation.The external medicine composition of the treatment gynaecological imflammation, is made: 0-3 parts of pearl, 0-2 parts of muskone, 1-12 parts of the coptis, 5-15 parts of kuh-seng, 0-16 parts of Semen Ricini, 5-16 parts of cortex dictamni, 6-15 parts of Chinese gall, 5-10 parts of alumen, 10-20 parts callicarpa nudiflora, 2-8 parts of safflower, 1-6 parts of lanatechead saussurea herb with flower, 5-10 parts of pomegranate flower, 0-15 parts of almond, 3-13 parts of frutus cnidii, 4-12 parts of pericarpium zanthoxyli, 3-13 parts of Cortex Phellodendri, 4-14 parts of borax and 0-3 parts of borneol of the raw material of following parts by weight.The invention also discloses the applications of the external application Chinese medicine of above-mentioned treatment gynaecological imflammation combination.External application Chinese medicine combination of the invention, it is obvious to gynaecological imflammation effect, any toxic side effect is not present, curative effect is thorough, does not recur after drug withdrawal.

Description

A kind of external medicine composition that treating gynaecological imflammation and its application
Technical field
The present invention relates to a kind of external medicine composition for treating gynaecological imflammation and its applications, belong to traditional chinese medicine preparation technology neck Domain.
Background technique
Gynaecological imflammation is the common disease of women, is primarily referred to as female sex organ such as vulva, vagina etc. by various causes It is inflamed after germ infection.Inflammation often shows as vulva and pruritus of vagina, and locally generation is rotten to the corn for some, with cusalgia, urodynia, urine Frequently, vaginal fluid increase, redness etc..According to the statistics of the World Health Organization, the adult female in the whole world about 87% suffers from different journeys The married femle of the gynaecological imflammation of degree, China 70% suffers from different degrees of gynaecological imflammation.In recent years, the illness rate of gynaecological imflammation Obvious ascendant trend is presented.Gynaecological imflammation is not only caused great harm to the health of women, is also resulted in not when serious Pregnant, ectopic pregnancy.
The drug for the treatment of gynaecological imflammation is broadly divided into Western medicine, Chinese medicine and Integrated TCM at present.Medical treatment woman at present Section's inflammation, drug used mainly utilize antibiotics and steroids, and long-time service can cause certain damage to organs such as liver kidneys Evil, and be easy that germ is made to generate drug resistance, it destroys vagina and causes the mutual restricting relation between flora and lead to flora imbalance, break Bad vagina is self-cleaning and defence capability, leads to Relapse rate, cannot thoroughly eradicate.Although Chinese medicine safety is preferable, treatment cycle It is long, curative effect is unobvious, it is also indefinite that patient's chance of becoming pregnant can be increased.
To sum up, it needs to develop a kind of new external medicine composition and preparation method thereof for treating gynaecological imflammation, to make up Drawbacks described above.
Summary of the invention
An object of the present invention is to provide a kind of external medicine composition for treating gynaecological imflammation.Treatment of the invention The external medicine composition of gynaecological imflammation, with clearing heat and detoxicating eliminating dampness, dispelling wind and arresting itching analgesic, antibacterial anti-inflammatory, mould proof deodorization function Effect, it is obvious to gynaecological imflammation effect, any toxic side effect is not present, curative effect is thorough, does not recur after drug withdrawal, and feel refrigerant after using It is pleasant, it is easy to be accepted by patients.
The technical scheme to solve the above technical problems is that a kind of external application Chinese medicine combination for treating gynaecological imflammation Object is made of the raw material of following parts by weight: 0-3 parts of pearl, 0-2 parts of muskone, 5-15 parts of the coptis, 5-15 parts of kuh-seng, castor-oil plant 0-16 parts of benevolence, 5-16 parts of cortex dictamni, 6-15 parts of Chinese gall, 5-10 parts of alumen, 10-20 parts callicarpa nudiflora, 2-8 parts of safflower, snow 1-6 parts of lotus flower, 5-10 parts of pomegranate flower, 0-15 parts of almond, 3-13 parts of frutus cnidii, 4-12 parts of pericarpium zanthoxyli, 3-13 parts of Cortex Phellodendri, borax 4-14 Part and borneol 0-3 parts.
The introduction of the effect of raw material that the present invention chooses:
Pearl: the Pharmacopoeia of the People's Republic of China and " dictionary of medicinal plant " indicate: there is pearl arresting convulsion of calming the nerves, improving eyesight to go Screen, solution taking poison and growing muscle due and other effects, modern study also show that pearl is improving the immunity of the human body, delaying senescence, freckle removing and whitening, supplementing calcium Matter etc. all has unique effect.
Muskone: warm-natured, nontoxic, bitter.Enter the heart, spleen, Liver Channel, has the function of resuscitation with aromatics, clearing and activating the channels and collaterals, scattered silt.
The coptis: alias: taste connects, river connects, Rhizoma Coptidis, belongs to Ranunculaceae, Coptis herbaceos perennial, cold in nature, bitter is returned The heart, liver, spleen, gallbladder, stomach, large intestine channel, there is the effect of heat-clearing and damp-drying drug, purging fire for removing toxin.
Kuh-seng: alias: wild Chinese scholartree, Hao Hanzhi, matrine, bone, Chinese scholartree, Albizzia kalkora, matrine, chuanshentong, phoenix claw, Niu Can, taste Hardship, it is cold in nature, return liver, kidney, large intestine, small intestinl channel, there is the effect of heat-clearing, eliminating dampness, desinsection.
Semen Ricini: the seed of euphorbia plant castor-oil plant, have detumescence and drawing out poison, rush down under lead to the effect of stagnant.
Cortex dictamni: alias dittany bark, stereotyped writing ox, seguin argyreia herb, sheep fresh grass, it is bitter, salty, it is cold in nature, returns spleen, lung, small intestine, stomach, Bladder meridian has the effect of heat-clearing and damp-drying drug, dispelling wind and arresting itching, removing toxic substances.
Chinese gall: for the drying insect gall on Anacardiaceae plant Chinese sumac, potanin sumac or redpunjab sumac root leaf, mainly by melaphis chinensis Baker It is parasitic and formed.It is cold in nature, it is sour, puckery, there is the effect of astringing lung-QI fall fire, relieving diarrhea with astringents, arrest sweating hemostasis, hygroscopic sore, cures mainly the deficiency syndrome of the lung The illnesss such as chronic cough, protracted dysentery and diarrhea, hematochezia hemorrhoid blood, carbuncle sore tumefacting virus, skin moisture fester.
Alumen: alias forges alum, toast alum, alumen ustum, and sour, puckery, salty, cold in nature, return lung, Liver Channel are primarily adapted for use in and disappear Phlegm, eliminating dampness, antidiarrheal, hemostasis, removing toxic substances, desinsection etc..
Callicarpa nudiflora: Verenaceae Callicarpa bodinieri Levl. platymiscium, bitter, micro-pungent are mild-natured, there is the function of anti-inflammatory, removing toxic substances, convergence, hemostasis Effect.
Safflower: alias safron, west safflower, sweet in flavor, mild-natured, converge to heart and liver channels have the effect of activating microcirculation and removing stasis medicinal.
Lanatechead saussurea herb with flower: bitter, it is cold in nature, there is the effect of clearing heat and detoxicating, swelling and pain relieving.
Pomegranate flower: it is warm-natured, it is sour, there is the effect of clearing heat and detoxicating, puckery intestines hemostasis.
Almond: bitter, slightly warm in nature, return lung, large intestine channel have the effect of relieving cough and asthma sending down abnormally ascending, relax bowel and defecation.
Frutus cnidii: acrid flavour, hardship, it is warm-natured, return kidney channel, there is the effect of warming kidney and enhancing body, eliminating dampness, wind-dispelling, desinsection.
Pericarpium zanthoxyli: acrid flavour, property heat, returns spleen, stomach meridian have fragrant stomach invigorating, warming spleen and stomach for dispelling cold, damp dispelling and pain relieving, desinsection removing toxic substances, antipruritic solution The effect of raw meat.
Cortex Phellodendri: for the dry bark of rutaceae wampee or cork tree, bitter is cold in nature, returns kidney, bladder, large intestine channel, has The effect of heat-clearing and damp-drying drug, purging fire for removing toxin.
Borax: it is sweet in flavor, salty, it is cool in nature, it attaches to the lung and stomach meridians, there is the effect of heat-clearing and phlegm-dissolving, detoxifying and anticorrosive.
Borneol: acrid flavour, hardship, slightly cold, return heart, liver, lung channel have the function for leading to all keys, dissipating stagnated fire, going screen improving eyesight, swelling and pain relieving Effect.
Prescription solution:
It is callicarpa nudiflora in above-mentioned raw materials, have the effect of anti-inflammatory, removing toxic substances, convergence, hemostasis for monarch drug in a prescription.Frutus cnidii, kuh-seng, Cortex Phellodendri, the coptis, cortex dictamni, pericarpium zanthoxyli have warming spleen and stomach for dispelling cold, damp dispelling and pain relieving, let out fire removing toxic substances, antipruritic solution raw meat, desinsection, antimycotic function Effect is ministerial drug.Safflower, lanatechead saussurea herb with flower, pomegranate flower, Chinese gall, pearl, alumen, almond, Semen Ricini have menstruation regulating, activating microcirculation and removing stasis medicinal, Removing pattogenic heat from the blood and toxic material from the body, detumescence and drawing out poison lead to stagnant, relax bowel and defecation, relieving diarrhea with astringents, resolving stagnation for tranquilization, antibacterial desinsection, arresting convulsion of calming the nerves, removing toxic substances under rushing down The effect of myogenic, anti-aging is adjutant.Borax, muskone, borneol have resuscitation with aromatics, anti-inflammatory analgetic, scattered silt, promoting menstruation living The effect of network, heat-clearing and phlegm-dissolving, detoxifying and anticorrosive is to make medicine.Above each raw material synergistic effect, reaches antibacterial, antipruritic, desinsection jointly The effect of.
The external medicine composition for the treatment of gynaecological imflammation of the invention is secret prescription handed down in the family from generation to generation, is present inventor and teacher Mr. Dong Yifeng, after concentrating on studies for more than 50 years, is answered on the basis of chartering biography secret recipe by the clinic of tens of thousands of patients With to treatment gynaecological imflammation cure rate up to 95% or more, effective percentage is 100%, to cervical erosion, adnexitis, pelvic inflammatory disease, trichomonad Property yin powerful inflammation, colpomycosis, uterine prolapse, leukoplakia vulvae, vulva and vagina pruritus and drawn by the above illness The infertility risen, has special efficacy to abdominal pain caused by leukorrhea, further, it is also possible to prevent and treat venereal disease.
Based on the above technical solution, the present invention can also be improved as follows.
Further, be made of the raw material of following parts by weight: 3 parts of pearl, 0.1 part of muskone, 8 parts of the coptis, 10 parts of kuh-seng, 13 parts of Semen Ricini, 13 parts of cortex dictamni, 12 parts of Chinese gall, 8 parts of alumen, 20 parts callicarpa nudiflora, 5 parts of safflower, 3 parts of lanatechead saussurea herb with flower, stone 6 parts of pomegranate, 2 parts of almond, 6 parts of frutus cnidii, 10 parts of pericarpium zanthoxyli, 9 parts of Cortex Phellodendri, 8.5 parts of borax and 0.5 part of borneol.
Further, be made of the raw material of following parts by weight: 1 part of pearl, 1.5 parts of muskone, 9 parts of the coptis, 10 parts of kuh-seng, 13 parts of Semen Ricini, 10 parts of cortex dictamni, 11 parts of Chinese gall, 9 parts of alumen, 18 parts callicarpa nudiflora, 6 parts of safflower, 5 parts of lanatechead saussurea herb with flower, stone 10 parts of pomegranate, 10 parts of frutus cnidii, 7 parts of pericarpium zanthoxyli, 8 parts of Cortex Phellodendri, 9 parts of borax and 1 part of borneol.
Further, be made of the raw material of following parts by weight: 0.5 part of pearl, 1 part of muskone, 10 parts of the coptis, 8 parts of kuh-seng, 12 parts of Semen Ricini, 11 parts of cortex dictamni, 10 parts of Chinese gall, 8 parts of alumen, 17 parts callicarpa nudiflora, 3 parts of safflower, 2 parts of lanatechead saussurea herb with flower, stone 5 parts of pomegranate, 5 parts of almond, 10 parts of frutus cnidii, 8 parts of pericarpium zanthoxyli, 8 parts of Cortex Phellodendri, 5.5 parts of borax and 1.5 parts of borneol.
Further, it is made of the raw material of following parts by weight: 2 parts of pearl, 0.5 part of muskone, 12 parts of the coptis, Semen Ricini 12 Part, 13 parts of cortex dictamni, 12 parts of Chinese gall, 10 parts of alumen, 15 parts callicarpa nudiflora, 5 parts of safflower, 3 parts of lanatechead saussurea herb with flower, 7 parts of pomegranate flower, 3 parts of almond, 8 parts of frutus cnidii, 9 parts of pericarpium zanthoxyli, 9 parts of Cortex Phellodendri, 8 parts of borax and 1 part of borneol.
Further, it is made of the raw material of following parts by weight: 1 part of pearl, 0.7 part of muskone, 11 parts of the coptis, kuh-seng 13 Part, 12 parts of Semen Ricini, 13 parts of cortex dictamni, 10 parts of Chinese gall, 7 parts of alumen, 16 parts callicarpa nudiflora, 5 parts of safflower, 5 parts of lanatechead saussurea herb with flower, 7 parts of pomegranate flower, 5 parts of frutus cnidii, 8 parts of pericarpium zanthoxyli, 10 parts of Cortex Phellodendri, 8 parts of borax and 2 parts of borneol.
Further, it is made of the raw material of following parts by weight: 2.5 parts of pearl, 5 parts of the coptis, 13 parts of kuh-seng, Semen Ricini 10 Part, 12.5 parts of cortex dictamni, 13 parts of Chinese gall, 6 parts of alumen, 19 parts callicarpa nudiflora, 6 parts of safflower, 2 parts of lanatechead saussurea herb with flower, pomegranate flower 7 Part, 9 parts of frutus cnidii, 10 parts of pericarpium zanthoxyli, 9 parts of Cortex Phellodendri, 9 parts of borax and 1 part of borneol.
The second object of the present invention is to provide the application of the external medicine composition of above-mentioned treatment gynaecological imflammation.It is above-mentioned to control The external medicine composition for treating gynaecological imflammation can be used to prepare the drug for the treatment of gynaecological imflammation individually or as active component.
The technical scheme to solve the above technical problems is that the external medicine composition of above-mentioned treatment gynaecological imflammation Application in the drug for preparing treatment gynaecological imflammation individually or as active component.
The third object of the present invention is to provide a kind of traditional Chinese medicine for outer use for treating gynaecological imflammation.Above-mentioned external application Chinese medicine group Close object, can be added starch, microcrystalline cellulose, cocoa butter, carbomer, sodium benzoate, poloxamer, benzalkonium bromide it is a kind of or A variety of pharmaceutically acceptable auxiliary materials are used to prepare the traditional Chinese medicine for outer use of the treatment gynaecological imflammation of various dosage forms.
The technical scheme to solve the above technical problems is that a kind of traditional Chinese medicine for outer use for treating gynaecological imflammation, External medicine composition as described above is taken, starch, microcrystalline cellulose, cocoa butter, carbomer, sodium benzoate, pool Lip river is added The one or more pharmaceutically acceptable auxiliary materials of Sha Mu, benzalkonium bromide, routinely pill, suppository, powder or gel is made in technique Agent.
The fourth object of the present invention is to provide the preparation method of the traditional Chinese medicine for outer use of above-mentioned treatment gynaecological imflammation.This hair The preparation method of the traditional Chinese medicine for outer use of bright treatment gynaecological imflammation is simple, low in cost, and Chinese medicine is after hot fermentation, meeting Beneficial bacterium, multichain enzyme are generated, enteron aisle is easier to absorb, and the drug effect of Chinese medicine can increase 5 times or more, and wide market is suitble to rule Modelling production.
The technical scheme to solve the above technical problems is that a kind of traditional Chinese medicine for outer use for treating gynaecological imflammation Preparation method includes the following steps:
Take the raw material of following parts by weight: 0-3 parts of pearl, 0-2 parts of muskone, 5-15 parts of the coptis, 5-15 parts of kuh-seng, castor-oil plant 0-16 parts of benevolence, 5-16 parts of cortex dictamni, 6-15 parts of Chinese gall, 5-10 parts of alumen, 10-20 parts callicarpa nudiflora, 2-8 parts of safflower, snow 1-6 parts of lotus flower, 5-10 parts of pomegranate flower, 0-15 parts of almond, 3-13 parts of frutus cnidii, 4-12 parts of pericarpium zanthoxyli, 3-13 parts of Cortex Phellodendri, borax 4-14 Part and borneol 0-3 parts, by pearl, the coptis, kuh-seng, Semen Ricini, cortex dictamni, Chinese gall, alumen, callicarpa nudiflora, safflower, saussurea involucrata Flower, pomegranate flower, almond, frutus cnidii, pericarpium zanthoxyli, Cortex Phellodendri, borax and borneol after mixing, crush, 8 times of weight of above-mentioned medicinal material are added Purified water, boiling collects a medical fluid and a dregs of a decoction, and a dregs of a decoction add the purified water of 6 times of weight of a dregs of a decoction, steams It boils, collects secondary medical fluid, merge a medical fluid and secondary medical fluid, filter, concentration obtains medicinal extract;
Muskone is added in medicinal extract, starch, microcrystalline cellulose, cocoa butter, carbomer, benzene first is added in heating fermentation The one or more pharmaceutically acceptable auxiliary materials of sour sodium, poloxamer, benzalkonium bromide, routinely technique is made pill, suppository, dissipates Agent or gelling agent are to get the traditional Chinese medicine for outer use for arriving the treatment gynaecological imflammation.
The usage and the course for the treatment of of the traditional Chinese medicine for outer use for the treatment of gynaecological imflammation of the invention are as follows:
Under normal circumstances, the bacterium infection of all intravaginals, using pill, every ball is 6g.Every 3 days 1 balls, 6 balls are a treatment Journey.
The infection lesion of all vulvas when the symptoms such as redness, itch occurs in vulva, can use suppository, and every is 2g.Daily 1 Grain, 15 as a treatment course.
Such as, peculiar smell, abnormal leucorrhea can use powder or gelling agent to other situations.Powder be every 3g, daily one, 7 It is as a treatment course.Gelling agent is every 3g, and daily one, 7 as a treatment course.
When preventing and treating venereal disease using the traditional Chinese medicine for outer use for the treatment of gynaecological imflammation of the invention, it should be noted that first clean vulva and again will Pill is put into vagina depths, and replacement in three days is primary;Pill crushing can be reconciled with warm water if any pruritus vulvae, leukoplakia vulvae Apply affected part, 6 one, the ball courses for the treatment of, until healing.
Though the traditional Chinese medicine for outer use for the treatment of gynaecological imflammation of the invention has special efficacy to above-mentioned gynaecological disease, also there is taboo, such as: The gynaecological disease as caused by protopathy should use simultaneously this traditional Chinese medicine for outer use in treatment protopathy;Underbelly slightly has discomfort when medication, The heavier patient's underbelly of inflammation has mild pain sense, belongs to normal.In addition, this product is externally applied drug, must not take orally.
Based on the above technical solution, the present invention can also be improved as follows.
Further, the partial size of the crushing is 80-100 mesh;The temperature of the boiling is 90 DEG C -98 DEG C, and the time is 0.5h-1.5h;The medicinal extract is 1.01 in 65 DEG C of -70 DEG C of relative densities;The temperature of the heating fermentation is 28 DEG C -35 DEG C, when Between be 6h-12h;The auxiliary material is one of starch, microcrystalline cellulose, cocoa butter, carbomer, sodium benzoate or a variety of.
Beneficial effects of the present invention:
(1) external medicine composition for the treatment of gynaecological imflammation of the invention, there is clearing heat and detoxicating eliminating dampness, dispelling wind and arresting itching to stop Bitterly, obvious to gynaecological imflammation effect the effect of antibacterial anti-inflammatory, mould proof deodorization, any toxic side effect is not present, curative effect is thorough, stops It is not recurred after medicine, and feels refrigerant pleasant after using, be easy to be accepted by patients.
(2) external medicine composition for the treatment of gynaecological imflammation of the invention, to cervical erosion, adnexitis, pelvic inflammatory disease, trichomonad Property yin powerful inflammation, colpomycosis, uterine prolapse, leukoplakia vulvae, vulva and vagina pruritus and drawn by the above illness The infertility risen, has special efficacy to abdominal pain caused by leukorrhea, further, it is also possible to prevent and treat venereal disease.
(3) external medicine composition for the treatment of gynaecological imflammation of the invention can be individually or as active component, for making The drug of standby treatment gynaecological imflammation.
(4) expense of the traditional Chinese medicine for outer use for the treatment of gynaecological imflammation of the invention is low, good effect, Small side effects, and medication It is convenient and efficient.
(5) preparation method of the traditional Chinese medicine for outer use for the treatment of gynaecological imflammation of the invention is simple, low in cost, market prospects It is wide, it is suitble to large-scale production.
Specific embodiment
Principles and features of the present invention are described below in conjunction with specific embodiment, example is served only for explaining this hair It is bright, it is not intended to limit the scope of the present invention.
Embodiment 1
The external medicine composition of the treatment gynaecological imflammation of the present embodiment, is made of the raw material of following weight: pearl 1kg, Muskone 1.5kg, coptis 9kg, kuh-seng 10kg, Semen Ricini 13kg, cortex dictamni 10kg, Chinese gall 11kg, alumen 9kg, nakedflower are purple Pearl 18kg, safflower 6kg, lanatechead saussurea herb with flower 5kg, pomegranate flower 10kg, frutus cnidii 10kg, pericarpium zanthoxyli 7kg, Cortex Phellodendri 8kg, borax 9kg and ice Piece 1kg.
The external medicine composition of above-mentioned treatment gynaecological imflammation is preparing treatment gynaecology inflammation individually or as active component Application in the drug of disease.
The traditional Chinese medicine for outer use of the treatment gynaecological imflammation of the present embodiment, takes external medicine composition as described above, is added Starch, microcrystalline cellulose and sodium benzoate, routinely pill is made in technique.
The preparation method of the traditional Chinese medicine for outer use of above-mentioned treatment gynaecological imflammation, includes the following steps:
Take the raw material of following weight: pearl 1kg, muskone 1.5kg, coptis 9kg, kuh-seng 10kg, Semen Ricini 13kg, shaggy-fruited dittany Skin 10kg, Chinese gall 11kg, alumen 9kg, callicarpa nudiflora 18kg, safflower 6kg, lanatechead saussurea herb with flower 5kg, pomegranate flower 10kg, frutus cnidii 10kg, pericarpium zanthoxyli 7kg, Cortex Phellodendri 8kg, borax 9kg and borneol 1kg.By pearl, the coptis, kuh-seng, Semen Ricini, cortex dictamni, Chinese gall, Alumen, callicarpa nudiflora, safflower, lanatechead saussurea herb with flower, pomegranate flower, almond, frutus cnidii, pericarpium zanthoxyli, Cortex Phellodendri, borax and borneol are uniformly mixed Afterwards, 80 mesh are crushed to, the purified water of above-mentioned 8 times of weight of medicinal material is added, 90 DEG C of boiling 1.5h collect a medical fluid and a medicine Slag, a dregs of a decoction add the purified water of 6 times of weight of a dregs of a decoction, and 90 DEG C of boiling 1.5h collect secondary medical fluid, merge a medicine Liquid and secondary medical fluid filter, and concentration obtains medicinal extract, which is 1.01 in 65 DEG C of -70 DEG C of relative densities;
Muskone is added in medicinal extract, starch 22kg, microcrystalline cellulose 20kg and benzoic acid is added in 32 DEG C of temperature fermentation 8h Sodium 1.5kg, routinely pill is made to get the traditional Chinese medicine for outer use of the treatment gynaecological imflammation is arrived in technique.Specification: every ball is 6g。
Embodiment 2
The external medicine composition of the treatment gynaecological imflammation of the present embodiment, is made: pearl of the raw material of following weight 0.5kg, muskone 1kg, coptis 5kg, kuh-seng 9kg, Semen Ricini 12kg, cortex dictamni 11kg, Chinese gall 10kg, alumen 9kg, nakedflower Callicarpa bodinieri Levl. 18kg, safflower 3kg, lanatechead saussurea herb with flower 2kg, pomegranate flower 5kg, almond 5kg, frutus cnidii 10kg, pericarpium zanthoxyli 8kg, Cortex Phellodendri 8kg, boron Sand 5.5kg and borneol 1.5kg.
The external medicine composition of above-mentioned treatment gynaecological imflammation is preparing treatment gynaecology inflammation individually or as active component Application in the drug of disease.
The traditional Chinese medicine for outer use of the treatment gynaecological imflammation of the present embodiment, takes external medicine composition as described above, is added Sodium benzoate, cocoa butter and poloxamer, routinely suppository is made in technique.
The preparation method of the traditional Chinese medicine for outer use of above-mentioned treatment gynaecological imflammation, includes the following steps:
Take the raw material of following weight: pearl 0.5kg, muskone 1kg, coptis 5kg, kuh-seng 9kg, Semen Ricini 12kg, shaggy-fruited dittany Skin 11kg, Chinese gall 10kg, alumen 9kg, callicarpa nudiflora 18kg, safflower 3kg, lanatechead saussurea herb with flower 2kg, pomegranate flower 5kg, almond 5kg, Frutus cnidii 10kg, pericarpium zanthoxyli 8kg, Cortex Phellodendri 8kg, borax 5.5kg and borneol 1.5kg, by pearl, the coptis, kuh-seng, Semen Ricini, shaggy-fruited dittany Skin, Chinese gall, alumen, callicarpa nudiflora, safflower, lanatechead saussurea herb with flower, pomegranate flower, almond, frutus cnidii, pericarpium zanthoxyli, Cortex Phellodendri, borax and borneol After mixing, 80 mesh are crushed to, the purified water of 8 times of weight of medicinal material is added, 94 DEG C of boiling 1h collect a medical fluid and a medicine Slag, a dregs of a decoction add the purified water of 6 times of weight of a dregs of a decoction, and 94 DEG C of boiling 1h collect secondary medical fluid, merge a medical fluid With secondary medical fluid, filtering is concentrated to get medicinal extract, which is 1.01 in 65 DEG C of -70 DEG C of relative densities;
Muskone is added in medicinal extract, sodium benzoate 1kg, cocoa butter 15kg and pool Lip river is added in 30 DEG C of temperature fermentation 12h Husky nurse 18kg, routinely suppository is made to get the traditional Chinese medicine for outer use of the treatment gynaecological imflammation is arrived in technique.Specification: every 2g.
Embodiment 3
The external medicine composition of the treatment gynaecological imflammation of the present embodiment, is made of the raw material of following weight: pearl 2kg, Muskone 0.5kg, coptis 12kg, Semen Ricini 12kg, cortex dictamni 13kg, Chinese gall 12kg, alumen 10kg, callicarpa nudiflora 15kg, Safflower 5kg, lanatechead saussurea herb with flower 3kg, pomegranate flower 7kg, almond 3kg, frutus cnidii 8kg, pericarpium zanthoxyli 9kg, Cortex Phellodendri 9kg, borax 8kg and borneol 1kg。
The external medicine composition of above-mentioned treatment gynaecological imflammation is preparing treatment gynaecology inflammation individually or as active component Application in the drug of disease.
The traditional Chinese medicine for outer use of the treatment gynaecological imflammation of the present embodiment, takes external medicine composition as described above, is added Starch and sodium benzoate, routinely powder is made in technique.
The preparation method of the traditional Chinese medicine for outer use of above-mentioned treatment gynaecological imflammation, includes the following steps:
Take the raw material of following weight: pearl 2kg, muskone 0.5kg, coptis 12kg, Semen Ricini 12kg, cortex dictamni 13kg, Chinese gall 12kg, alumen 10kg, callicarpa nudiflora 15kg, safflower 5kg, lanatechead saussurea herb with flower 3kg, pomegranate flower 7kg, almond 3kg, frutus cnidii 8kg, pericarpium zanthoxyli 9kg, Cortex Phellodendri 9kg, borax 8kg and borneol 1kg, by the pearl, coptis, kuh-seng, Semen Ricini, cortex dictamni, Chinese gall, withered Alum, callicarpa nudiflora, safflower, lanatechead saussurea herb with flower, pomegranate flower, almond, frutus cnidii, pericarpium zanthoxyli, Cortex Phellodendri, borax and borneol after mixing, 80 mesh are crushed to, the purified water of 8 times of weight of medicinal material is added, 98 DEG C of boiling 0.5h collect a medical fluid and a dregs of a decoction, a medicine Slag adds the purified water of 6 times of weight, and 98 DEG C of boiling 0.5h collect secondary medical fluid, merges a medical fluid and secondary medical fluid, mistake Filter, concentration, obtains medicinal extract, which is 1.01 in 65 DEG C of -70 DEG C of relative densities;
Muskone is added in medicinal extract, starch 21kg and sodium benzoate 2kg is added, routinely work in 35 DEG C of temperature fermentation 6h Powder is made to get the traditional Chinese medicine for outer use of the treatment gynaecological imflammation is arrived in skill.Specification: every 3g.
Embodiment 4
The traditional Chinese medicine for outer use of the treatment gynaecological imflammation of the present embodiment, is made: pearl 1kg, musk deer of the raw material of following weight It is ketone musk 0.7kg, coptis 11kg, kuh-seng 13kg, Semen Ricini 12kg, cortex dictamni 13kg, Chinese gall 10kg, alumen 6kg, callicarpa nudiflora 16kg, safflower 5kg, lanatechead saussurea herb with flower 5kg, pomegranate flower 7kg, frutus cnidii 5kg, pericarpium zanthoxyli 8kg, Cortex Phellodendri 10kg, borax 8kg and borneol 2kg。
The external medicine composition of above-mentioned treatment gynaecological imflammation is preparing treatment gynaecology inflammation individually or as active component Application in the drug of disease.
The traditional Chinese medicine for outer use of the treatment gynaecological imflammation of the present embodiment, takes external medicine composition as described above, is added Benzalkonium bromide and carbomer, routinely gelling agent is made in technique.
The preparation method of the traditional Chinese medicine for outer use of above-mentioned treatment gynaecological imflammation, includes the following steps:
Take raw material pearl 1kg, muskone 0.7kg, coptis 11kg, kuh-seng 13kg, the Semen Ricini 12kg, shaggy-fruited dittany of following weight Skin 13kg, Chinese gall 10kg, alumen 6kg, callicarpa nudiflora 16kg, safflower 5kg, lanatechead saussurea herb with flower 5kg, pomegranate flower 7kg, frutus cnidii 5kg, pericarpium zanthoxyli 8kg, Cortex Phellodendri 10kg, borax 8kg and borneol 2kg, by pearl, the coptis, kuh-seng, Semen Ricini, cortex dictamni, Chinese gall, Alumen, callicarpa nudiflora, safflower, lanatechead saussurea herb with flower, pomegranate flower, almond, frutus cnidii, pericarpium zanthoxyli, Cortex Phellodendri, borax and borneol are uniformly mixed Afterwards, 80 mesh are crushed to, the purified water of 8 times of medicinal material amounts is added, 90 DEG C of boiling 1.2h collect a medical fluid and a dregs of a decoction, once The dregs of a decoction add the purified water of 6 times of amounts, and 98 DEG C of boiling 0.5h collect secondary medical fluid, merge a medical fluid and secondary medical fluid, mistake Filter, is concentrated to get medicinal extract, which is 1.01 in 65 DEG C of -70 DEG C of relative densities;
Muskone, 33 DEG C of temperature fermentation 9h are added in medicinal extract, the purified water and benzene that 5 times of weight of medicinal extract are added prick bromine Ammonium 1kg and carbomer 4kg, routinely gelling agent is made to get the traditional Chinese medicine for outer use of the treatment gynaecological imflammation is arrived in technique.Rule Lattice: every 3g.
Typical clinical example 1
Road, 40 years old, province, Henan Province people from Lin County.Pain in the loins is serious, takes action extremely difficult, leukorrhea has fishy smell.Using this The traditional Chinese medicine for outer use for the treatment gynaecological imflammation that inventive embodiments 2 obtain, daily 1,15 courses for the treatment of have used three courses for the treatment of Afterwards, illness is all eliminated, and end is recurred again so far.
Typical clinical example 2
Mr. Wang, 32 years old, Henan Province people from city, Mi County.It is three degree of cervical erosion through hospital inspection Check, pain in the loins and external genital itching, no Energy is crossed property life and is controlled, and goodwill as between spouses has been seriously affected.Using the external application Chinese medicine system for the treatment gynaecological imflammation that the embodiment of the present invention 1 obtains Agent, every 3 days 1 balls, 6 balls are as a treatment course.It fully recovers after two courses for the treatment of, love life conjunction is humorous, and end is recurred again so far.
Typical clinical example 3
Liu, 28 years old, Henan Province people from city, Mi County.Five Nian Buyu after marriage, hospital examine the sub- official's depauperation of Check system and because of appendixs Surgical adhesions cannot give birth to.The traditional Chinese medicine for outer use for treating gynaecological imflammation obtained using the embodiment of the present invention 4, daily 1,7 Days as a treatment course.After four courses for the treatment of, inflammation disappears, that is, raw son of becoming pregnant, and end is recurred again so far.
Typical clinical example 4
Zhang Guoying, 43 years old, Henan Province people from city, Mi County.It is in because suffering from gynaecological disease Long-term sick leave.It is obtained using the embodiment of the present invention 3 The traditional Chinese medicine for outer use of the treatment gynaecological imflammation arrived, daily one, 7 days as a course for the treatment of.It fully recovers after six courses for the treatment of, inflammation disappears It loses, it is normal to go to work, and end is recurred again so far.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of external medicine composition for treating gynaecological imflammation, which is characterized in that be made of the raw material of following parts by weight: precious 0-3 parts of pearl, 0-2 parts of muskone, 1-12 parts of the coptis, 5-15 parts of kuh-seng, 0-16 parts of Semen Ricini, 5-16 parts of cortex dictamni, Chinese gall 6- 15 parts, 5-10 parts of alumen, 10-20 parts callicarpa nudiflora, 2-8 parts of safflower, 1-6 parts of lanatechead saussurea herb with flower, 5-10 parts of pomegranate flower, almond 0-15 Part, 3-13 parts of frutus cnidii, 4-12 parts of pericarpium zanthoxyli, 3-13 parts of Cortex Phellodendri, 4-14 parts of borax and 0-3 parts of borneol.
2. the external medicine composition for the treatment of gynaecological imflammation according to claim 1, which is characterized in that by following parts by weight Several raw materials are made: 3 parts of pearl, 0.1 part of muskone, 8 parts of the coptis, 5 parts of kuh-seng, 13 parts of Semen Ricini, 13 parts of cortex dictamni, Chinese gall 12 parts, 9 parts of alumen, 15 parts callicarpa nudiflora, 5 parts of safflower, 3 parts of lanatechead saussurea herb with flower, 6 parts of pomegranate flower, 2 parts of almond, 6 parts of frutus cnidii, river 10 parts of green pepper, 9 parts of Cortex Phellodendri, 8.5 parts of borax and 0.5 part of borneol.
3. the external medicine composition for the treatment of gynaecological imflammation according to claim 1, which is characterized in that by following parts by weight Several raw materials are made: 1 part of pearl, 1.5 parts of muskone, 9 parts of the coptis, 10 parts of kuh-seng, 13 parts of Semen Ricini, 10 parts, five times of cortex dictamni Son 11 parts, 8 parts of alumen, 18 parts callicarpa nudiflora, 6 parts of safflower, 5 parts of lanatechead saussurea herb with flower, 8 parts of pomegranate flower, 10 parts of frutus cnidii, 7 parts of pericarpium zanthoxyli, 8 parts of Cortex Phellodendri, 9 parts of borax and 1 part of borneol.
4. the external medicine composition for the treatment of gynaecological imflammation according to claim 1, which is characterized in that by following parts by weight Several raw materials are made: 0.5 part of pearl, 1 part of muskone, 5 parts of the coptis, 12 parts of kuh-seng, 12 parts of Semen Ricini, 11 parts, five times of cortex dictamni Son 10 parts, 7 parts of alumen, 15 parts callicarpa nudiflora, 3 parts of safflower, 2 parts of lanatechead saussurea herb with flower, 5 parts of pomegranate flower, 5 parts of almond, 10 parts of frutus cnidii, 8 parts of pericarpium zanthoxyli, 8 parts of Cortex Phellodendri, 5.5 parts of borax and 1.5 parts of borneol.
5. the external medicine composition for the treatment of gynaecological imflammation according to claim 1, which is characterized in that by following parts by weight Several raw materials are made: 2 parts of pearl, 0.5 part of muskone, 12 parts of the coptis, 12 parts of Semen Ricini, 13 parts of cortex dictamni, 12 parts of Chinese gall, withered 10 parts of alum, 20 parts callicarpa nudiflora, 5 parts of safflower, 3 parts of lanatechead saussurea herb with flower, 7 parts of pomegranate flower, 3 parts of almond, 8 parts of frutus cnidii, 9 parts of pericarpium zanthoxyli, 9 parts of Cortex Phellodendri, 8 parts of borax and 1 part of borneol.
6. the external medicine composition for the treatment of gynaecological imflammation according to claim 1, which is characterized in that by following parts by weight Several raw materials are made: 1 part of pearl, 0.7 part of muskone, 11 parts of the coptis, 13 parts of kuh-seng, 12 parts of Semen Ricini, 13 parts, five times of cortex dictamni Son 10 parts, 9 parts of alumen, 16 parts callicarpa nudiflora, 5 parts of safflower, 5 parts of lanatechead saussurea herb with flower, 7 parts of pomegranate flower, 5 parts of frutus cnidii, 8 parts of pericarpium zanthoxyli, 10 parts of Cortex Phellodendri, 8 parts of borax and 2 parts of borneol.
7. a kind of external medicine composition for the treatment of gynaecological imflammation as claimed in any one of claims 1 to 6 is individually or as activity Application of the component in the drug of preparation treatment gynaecological imflammation.
8. a kind of traditional Chinese medicine for outer use for treating gynaecological imflammation, which is characterized in that take the described in any item external applications of claim 1-7 One or more pharmaceutically acceptable auxiliary materials are added in Chinese medicine composition, and routinely pill, suppository, powder or solidifying is made in technique Jelly.
9. a kind of preparation method for the traditional Chinese medicine for outer use for treating gynaecological imflammation, which comprises the steps of:
Take the raw material of following parts by weight: 0-3 parts of pearl, 0-2 parts of muskone, 1-12 parts of the coptis, 5-15 parts of kuh-seng, Semen Ricini 0- 16 parts, 5-16 parts of cortex dictamni, 6-15 parts of Chinese gall, 5-10 parts of alumen, 10-20 parts callicarpa nudiflora, 2-8 parts of safflower, lanatechead saussurea herb with flower 1-6 parts, 5-10 parts of pomegranate flower, 0-15 parts of almond, 3-13 parts of frutus cnidii, 4-12 parts of pericarpium zanthoxyli, 3-13 parts of Cortex Phellodendri, 4-14 parts of borax and 0-3 parts of borneol, by pearl, the coptis, kuh-seng, Semen Ricini, cortex dictamni, Chinese gall, alumen, callicarpa nudiflora, safflower, lanatechead saussurea herb with flower, Pomegranate flower, almond, frutus cnidii, pericarpium zanthoxyli, Cortex Phellodendri, borax and borneol after mixing, crush, 8 times of weight of above-mentioned medicinal material are added A medical fluid and a dregs of a decoction are collected in purified water, boiling, and a dregs of a decoction add the purified water of 6 times of weight of a dregs of a decoction, are steamed It boils, collects secondary medical fluid, merge a medical fluid and secondary medical fluid, filter, concentration obtains medicinal extract;
Muskone is added in medicinal extract, one or more pharmaceutically acceptable auxiliary materials are added, routinely technique system in heating fermentation The traditional Chinese medicine for outer use of the treatment gynaecological imflammation is arrived at pill, suppository, powder or gelling agent.
10. the preparation method of the traditional Chinese medicine for outer use for the treatment of gynaecological imflammation according to claim 9, which is characterized in that institute The partial size for stating crushing is 80-100 mesh;The temperature of the boiling is 90 DEG C -98 DEG C, and the time is 0.5h-1.5h;The medicinal extract It is 1.01 in 65 DEG C of -70 DEG C of relative densities;The temperature of the heating fermentation is 28 DEG C -35 DEG C, time 6h-12h;The auxiliary material For one of starch, microcrystalline cellulose, cocoa butter, carbomer, sodium benzoate, poloxamer, benzalkonium bromide or a variety of.
CN201910059519.XA 2019-01-22 2019-01-22 A kind of external medicine composition that treating gynaecological imflammation and its application Pending CN109568452A (en)

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