CN109562124A - 用于处理肌腱退化的方法和组合物 - Google Patents

用于处理肌腱退化的方法和组合物 Download PDF

Info

Publication number
CN109562124A
CN109562124A CN201780039455.6A CN201780039455A CN109562124A CN 109562124 A CN109562124 A CN 109562124A CN 201780039455 A CN201780039455 A CN 201780039455A CN 109562124 A CN109562124 A CN 109562124A
Authority
CN
China
Prior art keywords
composition
tendon
carbohydrate
composition according
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780039455.6A
Other languages
English (en)
Chinese (zh)
Inventor
C·D·怀特
E·S·安
S·D·诺尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anika Therapeutics Inc
Original Assignee
Anika Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anika Therapeutics Inc filed Critical Anika Therapeutics Inc
Publication of CN109562124A publication Critical patent/CN109562124A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/386—Ligaments, tendons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/10—Materials or treatment for tissue regeneration for reconstruction of tendons or ligaments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Closures For Containers (AREA)
CN201780039455.6A 2016-04-27 2017-04-26 用于处理肌腱退化的方法和组合物 Pending CN109562124A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662328396P 2016-04-27 2016-04-27
US62/328,396 2016-04-27
US201662367377P 2016-07-27 2016-07-27
US62/367,377 2016-07-27
PCT/US2017/029635 WO2017189723A1 (en) 2016-04-27 2017-04-26 Compositions for use in treating tendon degeneration

Publications (1)

Publication Number Publication Date
CN109562124A true CN109562124A (zh) 2019-04-02

Family

ID=58709560

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780039455.6A Pending CN109562124A (zh) 2016-04-27 2017-04-26 用于处理肌腱退化的方法和组合物

Country Status (15)

Country Link
US (1) US10441677B2 (https=)
EP (1) EP3448394B1 (https=)
JP (1) JP6826657B2 (https=)
KR (1) KR20190009303A (https=)
CN (1) CN109562124A (https=)
AU (1) AU2017257956B2 (https=)
CA (1) CA3021764C (https=)
IL (1) IL262507B (https=)
MX (1) MX375382B (https=)
NZ (1) NZ747413A (https=)
RU (1) RU2018141386A (https=)
SG (2) SG10201913342UA (https=)
TW (2) TWI755392B (https=)
WO (1) WO2017189723A1 (https=)
ZA (1) ZA201807136B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018399962B2 (en) 2018-01-02 2024-11-14 Cartiheal (2009) Ltd. Implantation tool and protocol for optimized solid substrates promoting cell and tissue growth
JP2024006681A (ja) * 2022-07-04 2024-01-17 学校法人近畿大学 生体材料
KR102940883B1 (ko) * 2022-12-27 2026-03-17 차의과학대학교 산학협력단 비타민 d를 포함하는 건병증 또는 근육손상 치료용 히알루론산 하이드로겔계 약물 전달 시스템 및 이의 제조방법
WO2025096427A1 (en) * 2023-10-29 2025-05-08 Brown David Donaldson Methods for treating lower back pain with hyaluronic acid

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1859918A (zh) * 2003-10-09 2006-11-08 罗伯特·约翰·佩特雷拉 使用透明质酸治疗急性和过劳扭伤、拉伤的方法
CN102665412A (zh) * 2009-09-23 2012-09-12 克能药物有限公司 用于诱导或加强结缔组织修复的组合物和方法
CN104703612A (zh) * 2012-09-26 2015-06-10 骨治疗公司 包含溶剂/去污剂处理过的血浆(s/d血浆)的制剂及其用途

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2946819A (en) 1958-04-14 1960-07-26 Gen Aniline & Film Corp Process of producing carbodimides
DE1156401B (de) 1960-05-24 1963-10-31 Bayer Ag Verfahren zur Herstellung von Carbodiimiden
DE1149712B (de) 1961-11-14 1963-06-06 Bayer Ag Verfahren zur Herstellung von Carbodiimiden
US3644456A (en) 1964-08-12 1972-02-22 Upjohn Co Di((isocyanatobenzyl)-phenyl) carbodiimides and preparation of organic carbodiimides
US3972933A (en) 1974-05-28 1976-08-03 Monsanto Company Preparation of carbodiimides from ureas by dehydration
GB1476088A (en) 1975-04-03 1977-06-10 Ici Ltd Carbodiimides
DE2556760A1 (de) 1975-12-17 1977-06-30 Hoechst Ag Verfahren zur herstellung von carbodiimiden
GB1584153A (en) 1976-09-22 1981-02-04 Ici Ltd Carbodimides
US4066629A (en) 1976-10-28 1978-01-03 Celanese Corporation Process for preparing carbodiimides utilizing a phosphonium salt catalyst
US4098973A (en) 1977-01-31 1978-07-04 The Upjohn Company Compounds and process
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
ITPD940054A1 (it) 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
DE69809892T2 (de) 1997-04-04 2003-08-28 Fidia Advanced Biopolymers S.R.L., Brindisi N-sulfatierte hyaluronsäureverbindungen, ihre derivate und verfahren zu ihrer herstellung
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
ATE243049T1 (de) 1999-12-09 2003-07-15 Biosyntech Canada Inc Mineral-polymer hybrid-zusammensetzung
ATE392907T1 (de) 2000-07-28 2008-05-15 Anika Therapeutics Inc Bioabsorbierbare kompositmaterialien aus derivatisierter hyaluronsäure
IT1317359B1 (it) 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Polisaccaridi percarbossilati, quali l'acido ialuronico, processo perla loro preparazione e loro impiego in campo farmaceutico e
IT1317358B1 (it) 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Derivati cross-linkati dell'acido ialuronico.
ATE312076T1 (de) 2001-02-22 2005-12-15 Anika Therapeutics Inc Thiol-modifizierte hyaluronan-derivate
US20060272221A1 (en) 2001-11-29 2006-12-07 Treibacher Schleifmittel Gmbh Al2O3 and ZrO2 based abrasive grain, method for the production and use thereof
WO2003072157A1 (en) 2002-02-21 2003-09-04 Encelle, Inc. Immobilized bioactive hydrogel matrices as surface coatings
ITPD20020064A1 (it) 2002-03-12 2003-09-12 Fidia Advanced Biopolymers Srl Derivati esterei dell'acido ialuronico per la preparazione di idrogelda utilizzare in campo biomedico, sanitario e chirurgico e come sistem
ES2260616T3 (es) 2002-06-19 2006-11-01 Dr.H.C. Robert Mathys Stiftung Cemento hidraulico con base de fosfato de calcio destinado a uso quirurgico.
US8455458B2 (en) * 2002-10-16 2013-06-04 Arthrodynamic Technologies, Animal Health Division, Inc. Composition and method for treating connective tissue damage
DE10257554B4 (de) 2002-12-10 2008-04-10 Treibacher Schleifmittel Gmbh Schleifkörner mit einer Ummantelung aus einem wässrigen Bindemittel und einer komplexen feinkörnigen Oxidverbindung, Verfahren zur Behandlung derartiger Schleifkörner sowie ihre Verwendung für kunstharzgebundene Schleifmittel
US8124120B2 (en) 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
CA2633957A1 (en) 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid
EP1891984A1 (en) 2006-08-24 2008-02-27 Graftys Macroporous and highly resorbable apatitic calcium-phosphate cement
IT1393419B1 (it) 2009-03-19 2012-04-20 Medivis S R L Composizioni oftalmiche a base di acidi grassi polinsaturi omega-3 e omega-6.
CN102811622A (zh) * 2010-02-22 2012-12-05 生物模拟治疗公司 用于治疗腱病的血小板衍生生长因子组合物和方法
CA2838816C (en) 2011-06-09 2017-08-15 Zimmer Gmbh Instruments and devices for subchondral joint repair
EP2827914B1 (en) 2012-03-22 2019-05-08 TRB Chemedica International S.A. Method for repair of ligament or tendon
JP6721514B2 (ja) * 2014-02-20 2020-07-15 オルト リジェネレイティヴ テクノロジーズ インク．Ｏｒｔｈｏ Ｒｅｇｅｎｅｒａｔｉｖｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． 多血小板血漿と混合し、組織修復のためのインプラントを形成するための凍結乾燥ポリマー組成物及び／又は治療用関節内注射のための組成物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1859918A (zh) * 2003-10-09 2006-11-08 罗伯特·约翰·佩特雷拉 使用透明质酸治疗急性和过劳扭伤、拉伤的方法
CN102665412A (zh) * 2009-09-23 2012-09-12 克能药物有限公司 用于诱导或加强结缔组织修复的组合物和方法
CN104703612A (zh) * 2012-09-26 2015-06-10 骨治疗公司 包含溶剂/去污剂处理过的血浆(s/d血浆)的制剂及其用途

Also Published As

Publication number Publication date
RU2018141386A3 (https=) 2020-05-27
EP3448394A1 (en) 2019-03-06
AU2017257956A1 (en) 2018-11-15
WO2017189723A1 (en) 2017-11-02
TW201739457A (zh) 2017-11-16
SG11201809197XA (en) 2018-11-29
ZA201807136B (en) 2021-05-26
MX375382B (es) 2025-03-06
RU2018141386A (ru) 2020-05-27
CA3021764A1 (en) 2017-11-02
WO2017189723A9 (en) 2018-06-28
AU2017257956B2 (en) 2019-11-07
KR20190009303A (ko) 2019-01-28
EP3448394C0 (en) 2023-09-13
CA3021764C (en) 2021-01-19
TW202114712A (zh) 2021-04-16
SG10201913342UA (en) 2020-03-30
US10441677B2 (en) 2019-10-15
JP6826657B2 (ja) 2021-02-03
JP2019516784A (ja) 2019-06-20
EP3448394B1 (en) 2023-09-13
MX2018012964A (es) 2019-06-10
IL262507A (en) 2018-12-31
IL262507B (en) 2020-10-29
US20170326271A1 (en) 2017-11-16
NZ747413A (en) 2020-09-25
TWI755392B (zh) 2022-02-21

Similar Documents

Publication Publication Date Title
Duranti et al. Injectable hyaluronic acid gel for soft tissue augmentation: A clinical and histological study
JP7025039B2 (ja) 高い弾性を有するヒアルロナンの組成物およびその使用
CN109562124A (zh) 用于处理肌腱退化的方法和组合物
US7371399B2 (en) Polymer gel containing hyaluronic acid and collagen, and its use in joints
JP2012521270A (ja) 軟骨修復
TWI775934B (zh) 用於治療缺血的黏性組合物
CN111194220B (zh) 用于治疗缺血的肝素组合物
US20260115253A1 (en) Viscous composition for treating ischemia
HK40006859A (en) Compositions for use in treating tendon degeneration
HK40005732A (en) Compositions for use in treating tendon degeneration
HK40005732B (en) Compositions for use in treating tendon degeneration

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40006859

Country of ref document: HK

RJ01 Rejection of invention patent application after publication

Application publication date: 20190402

RJ01 Rejection of invention patent application after publication