CN109528856A - A kind of spray for preventing chicken respiratory tract disease - Google Patents
A kind of spray for preventing chicken respiratory tract disease Download PDFInfo
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- CN109528856A CN109528856A CN201710857512.3A CN201710857512A CN109528856A CN 109528856 A CN109528856 A CN 109528856A CN 201710857512 A CN201710857512 A CN 201710857512A CN 109528856 A CN109528856 A CN 109528856A
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- spray
- chicken
- respiratory tract
- radix astragali
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Fodder In General (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention is a kind of spray and preparation method thereof for preventing chicken respiratory tract disease, and selected medicinal material forms as follows by weight: 10~15g of cordate houttuynia, 5~10g of loguat leaf, 2~5g of Radix Astragali, 2~5g of Cynanchum glaucescens, 1~2g of pueraria lobata.Composition proportion common by weight are as follows: cordate houttuynia 10g, loguat leaf 10g, Radix Astragali 5g, Cynanchum glaucescens 3g, pueraria lobata 2g.The above five tastes add the water of 10 times of quality to decoct 2 times, and 2 hours every time, collecting decoction, filtering, filtrate was concentrated into about 100ml, it is cooling after with vinegar acid for adjusting pH 3.5~4.0, encapsulating to get.The present invention is brown liquid, there is tart flavour, application method are as follows: after adding 2 times of water dilutions, is atomized by atomizer or directly spraying to chicken head portion.
Description
Technical field
The present invention relates to veterinary medicine field, specially a kind of spray for preventing chicken respiratory tract disease and its preparation side
Method.
Background technique
With the fast development of animal husbandry, the respiratory disease of chicken becomes the most concerned problem in chicken farm, especially chicken
Atypical newcastle disease, infective bronchitis are diseases more serious in current livestock and poultry cultivation, become influence poultry industry
An important factor for sound development.
Infectious bronchitis of chicken is a kind of acute, high degree in contact, viral infectious.The dead of chicken can not only be caused
It dies, and chicken group's production performance decline can be caused, the price of deed reduces, and brings huge economic loss to poultry husbandry.Prevention is
Best treatment is also answered other than immunity inoculation, reinforcement feeding management, holding environmental sanitation etc. for the generation for preventing this disease
Carry out reasonable chemoprophylaxis.Part chicken infects this after being ill, long that antibiotic is selected to prevent secondary infection, but due to antibiotic meeting
Drug resistance is generated, the effect for leading to antibiotic worse and worse, still lacks the prevention method of special efficacy at present.
Summary of the invention
Technical problem solved by the invention is to provide a kind of spray for preventing chicken respiratory tract disease and its preparation side
Method, to solve the problems in background technique.
The technical problems to be solved by the invention are realized using following technical scheme:
The spray medicinal material for preventing chicken respiratory tract disease by weight, forms as follows: 10~15g of cordate houttuynia, 5~10g of loguat leaf,
2~5g of Radix Astragali, 2~5g of Cynanchum glaucescens, 1~2g of pueraria lobata.
In the present invention, raw material composition proportion common by weight are as follows: cordate houttuynia 10g, loguat leaf 10g, Radix Astragali 5g, Cynanchum glaucescens
3g, pueraria lobata 2g.
Prepare by following processing steps and technological parameter: the above five tastes add the water of 10 times of quality to decoct 2 times, and 2 is small every time
When, collecting decoction, filtering, filtrate is concentrated into about 100ml, it is cooling after with vinegar acid for adjusting pH 3.5~4.0, encapsulating to get.
The present invention is brown liquid, there is tart flavour, application method are as follows: after adding 2 times of water dilutions, by atomizer atomization or directly
It connects spraying to chicken head portion.
The beneficial effects of the present invention are: 1, it is obvious to prevention chicken respiratory tract disease effect;2, Direct spraying uses, operation side
Just, at low cost;3, the present invention is pure Chinese medicine product, and external application has no toxic side effect to chicken itself.
Raw material selected by the present invention and the parsing of each component and effect are as follows:
Cordate houttuynia: acrid flavour, cold, distributed in lung channel, clearing heat and detoxicating, inducing diuresis to remove edema can treat lung inflammation.
Loguat leaf: bitter is cold in nature, can clearing lung and relieving cough, control pulmonary tuberculosis cough.
Radix Astragali: can enhance body's immunity, there is wide antibacterial action.
Cynanchum glaucescens: can control asthma, main by dropping lung qi with flat cough and asthma.
Pueraria lobata: thirsty for pyreticosis, the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.
Medicinal material selected by this product can be used in the prevention to respiratory disease, no incompatibility.
Mucosa irritation test and toxicity on inhalation test are carried out to spray of the invention.
Spray of the invention is observed to the irritation of mucous membrane using to 50 chick atomized medicine introducing methods.As a result, atomization
Administration is nonirritant to the eyes of chicken, oral cavity, nasal cavity and throat mucous membrane, shows non-stimulated to mucous membrane by spray delivery mode
Property.Toxicity on inhalation test is carried out to 160 chickens using atomization.Without toxic reaction and death in test group animal 72h, in serum
Total protein content and enzymatic activity in the normal range, show spray of the invention to chicken without toxicity on inhalation, clinical application peace
Entirely.
Specific embodiment:
It is the embodiment of the present invention below, actual use of the invention is not limited to embodiment.
Take cordate houttuynia 5kg, loguat leaf 5kg, Radix Astragali 3kg, Cynanchum glaucescens 1kg, pueraria lobata 1kg.The above five tastes add 300kg water to decoct 2
Secondary, 2 hours every time, collecting decoction filtered, and filtrate is concentrated into about 100L, was filled with vinegar acid for adjusting pH 3.5~4.0 after cooling
Envelope.
Verification experimental verification is carried out to above-described embodiment in one chicken farm of Yancheng, selects healthy white feather chicken and manual simulation's natural sense
Each 500 plumage of infective bronchitis disease white feather chicken is contaminated, to 500 plumage health broiler chicken by spray delivery, emphasis sprays oral cavity, nasal cavity
Twice a day, 500 plumage white feather chickens after being sprayed after one day mark the diseased chicken with 500 plumages infection infective bronchitis to mist
It feeds 2 days, without chicken death during entire test, 500 spraying plumage chickens is detected two days later together, there is the appearance of 43 plumage chickens
Infection, 457 plumage chickens are without infection, prevention rate 91.4%.Prove that this product can effectively prevent chicken respiratory tract disease.
Specific embodiments of the present invention are described in detail above, but it is merely an example, the present invention is simultaneously unlimited
It is formed on particular embodiments described above.
Claims (3)
1. medicinal material selected by the spray of prevention chicken respiratory tract disease forms as follows by weight: 10~15g of cordate houttuynia, loguat leaf 5
~10g, 2~5g of Radix Astragali, 2~5g of Cynanchum glaucescens, 1~2g of pueraria lobata.
2. common proportion are as follows: cordate houttuynia 10g, loguat leaf 10g, Radix Astragali 5g, Cynanchum glaucescens 3g, pueraria lobata 2g.
3. gomi herbs as described in claim 1 adds the water of 10 times of quality to decoct 2 times, 2 hours every time, collecting decoction was filtered,
Filtrate is concentrated into about 100ml, it is cooling after with vinegar acid for adjusting pH 3.5~4.0, encapsulating to get.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201710857512.3A CN109528856A (en) | 2017-09-21 | 2017-09-21 | A kind of spray for preventing chicken respiratory tract disease |
Applications Claiming Priority (1)
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CN201710857512.3A CN109528856A (en) | 2017-09-21 | 2017-09-21 | A kind of spray for preventing chicken respiratory tract disease |
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Publication Number | Publication Date |
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CN109528856A true CN109528856A (en) | 2019-03-29 |
Family
ID=65827401
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CN201710857512.3A Pending CN109528856A (en) | 2017-09-21 | 2017-09-21 | A kind of spray for preventing chicken respiratory tract disease |
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CN (1) | CN109528856A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101884691A (en) * | 2010-07-13 | 2010-11-17 | 杨建彬 | Formula of traditional Chinese medicine for treating respiratory diseases of chicken |
CN102973728A (en) * | 2012-10-11 | 2013-03-20 | 镇江天和生物技术有限公司 | Chinese herbal medicine preparation for treating chicken infectious bronchitis |
CN104474027A (en) * | 2014-11-29 | 2015-04-01 | 郑州后羿制药有限公司 | Traditional Chinese veterinary medicine for treating avian respiratory infectious disease and preparation method of traditional Chinese veterinary medicine |
-
2017
- 2017-09-21 CN CN201710857512.3A patent/CN109528856A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101884691A (en) * | 2010-07-13 | 2010-11-17 | 杨建彬 | Formula of traditional Chinese medicine for treating respiratory diseases of chicken |
CN102973728A (en) * | 2012-10-11 | 2013-03-20 | 镇江天和生物技术有限公司 | Chinese herbal medicine preparation for treating chicken infectious bronchitis |
CN104474027A (en) * | 2014-11-29 | 2015-04-01 | 郑州后羿制药有限公司 | Traditional Chinese veterinary medicine for treating avian respiratory infectious disease and preparation method of traditional Chinese veterinary medicine |
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WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190329 |
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