CN109498800A - Application of the Lycium chinense glycopeptide in immunity, anti-aging and memory drug - Google Patents
Application of the Lycium chinense glycopeptide in immunity, anti-aging and memory drug Download PDFInfo
- Publication number
- CN109498800A CN109498800A CN201910003488.6A CN201910003488A CN109498800A CN 109498800 A CN109498800 A CN 109498800A CN 201910003488 A CN201910003488 A CN 201910003488A CN 109498800 A CN109498800 A CN 109498800A
- Authority
- CN
- China
- Prior art keywords
- drug
- lycium chinense
- chinense glycopeptide
- aging
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
This application discloses a kind of application of Lycium chinense glycopeptide in immunity, anti-aging and memory drug, oral class can be made in the purity of extraction Lycium chinense glycopeptide up to standard, it and is existed in powdered mode, associated patient can be by using the drug containing Lycium chinense glycopeptide, drug described herein may include food, health care product, special diet and drug etc., which can be improved autoimmunity, resists aging and the memory situation of itself is adjusted.It can be that a kind of new drug is clinically provided.
Description
Technical field
This application involves the application field of wolfberry fruit extract more particularly to a kind of Lycium chinense glycopeptide immunity, anti-aging and
Application in memory drug.
Background technique
Research has shown that currently, using the drug of raising immunity or the drug of anti-aging or tune medically in patient
After the drug for saving memory, it will appear light or heavy uncomfortable situation.To solve the above-mentioned problems, related personnel is to fructus lycii
The pharmacological property of glycopeptide has conducted extensive research, and finally found that Lycium chinense glycopeptide also has the function of that the above-mentioned illness for the treatment of still mentions at present
The Lycium chinense glycopeptide of taking-up mostly exists in powdered form.Do not occur using Lycium chinense glycopeptide production can be improved immunity,
Anti-aging and the related drugs etc. for adjusting memory.
Summary of the invention
This application provides a kind of application of Lycium chinense glycopeptide in immunity, anti-aging and memory drug, drug tools
It is improved immunity, anti-aging and the effect for adjusting memory.
In order to solve the above technical problems, this application provides a kind of Lycium chinense glycopeptides in immunity, anti-aging and memory medicine
Application in object, comprising:
Oral class medicine object or injection class drug is made in the purity of extraction Lycium chinense glycopeptide up to standard.
Preferably, the oral class medicine object includes the drug of capsule class drug or tablet class drug or oral solution posture；
Wherein, every capsule class drug contains the Lycium chinense glycopeptide 30-100mg, and every tablet class drug is containing the fructus lycii sugar
The drug of peptide 30-100mg, oral solution posture contain the Lycium chinense glycopeptide 30-100mg.
Preferably, the tablet class drug is made in the Lycium chinense glycopeptide to specifically include:
Weighed auxiliary material is crushed so that the auxiliary material is in powdered by pulverizer；
The Lycium chinense glycopeptide and powdered auxiliary material are carried out to proportion in proportion and obtain target material, by the target material
It is transported between granulation, and by after target material addition charging barrel, opens equipment, adjust the target component of the equipment, directly
It is in granular form to the target material；
By molding particle by oven drying, the moisture of the particle is made to be less than or equal to 5%；
After mixing by all particles investment mixing machine after drying, pack tying is sent to intermediate station；
In the case where external environment meets the requirements, the pack particle feeding in the intermediate station is entered into charging barrel and is pressed
Piece processing is to obtain the tablet class drug.
Preferably, the target component includes stirring frequency and chopping frequency.
Preferably, it is described to obtain to enter charging barrel progress compressing tablet process for the pack particle feeding by the intermediate station
Tablet class drug specifically includes:
When compacting first is default in the state that tabletting speed is less than or equal to 200,000 tablets hs, pressure is 10-30KN
Between；
It is less than or equal to 1% more than or equal to 4kgf, friability when average slice weight is greater than or equal to 0.8g, hardness, and not
There are after the piece of fracture, cracking and crushing, adjust the tabletting speed be ten thousand tablets h of 18-25 after it is re-compacted second it is default when
Between until obtaining satisfactory tablet class drug.
Preferably, it is described obtain satisfactory tablet class drug after, further includes:
Quality review confirmation is carried out again to the satisfactory tablet class drug.
Preferably, it after carrying out quality review confirmation again to the satisfactory tablet class drug described, also wraps
It includes:
Required color and date of manufacture are superscribed for the tablet class drug of requisite quality.
Preferably, injection class drug described in every class contains the Lycium chinense glycopeptide 30-100mg.
Compared with the prior art, this application discloses a kind of Lycium chinense glycopeptides in immunity, anti-aging and memory drug
Application, oral class can be made in the purity of extraction Lycium chinense glycopeptide up to standard, and existed in powdered mode, phase
Closing patient can may include food, health care product, special diet by using the drug containing Lycium chinense glycopeptide, drug described herein
And drug etc., the drug can be improved autoimmunity, resist aging and the memory situation of itself is adjusted.It can
With clinically to provide a kind of new drug.
Detailed description of the invention
For the clearer technical solution for illustrating the application, letter will be made to attached drawing needed in the embodiment below
The introduction wanted, it should be apparent that, it for those of ordinary skills, can be under the premise of not paying creativeness
It obtains other drawings based on these drawings.
Fig. 1 is a kind of Lycium chinense glycopeptide tableting processes flow chart provided by the embodiment of the present invention.
Specific embodiment
In order to make those skilled in the art better understand the technical solutions in the application, below in conjunction with attached drawing, it is right
Technical solution in the embodiment of the present application carries out clear and complete description.
The core of the application is to provide a kind of application of Lycium chinense glycopeptide in immunity, anti-aging and memory drug, should
Drug has the function of improving immunity, anti-aging and adjusts memory.
This application provides a kind of application of Lycium chinense glycopeptide in immunity, anti-aging and memory drug, comprising:
Oral class medicine object or injection class drug is made in the purity of extraction Lycium chinense glycopeptide up to standard.
The Lycium chinense glycopeptide mentioned in the embodiment of the present application includes Lycium chinense glycopeptide and polysaccharides peptide, is dried to from fructus lycii
Extract what separation obtained in ripe fruit.It is calculated by dry product, neutral polysaccharide content must not be less than 25%, and glucuronic acid content is greater than
5%, protein content is greater than 25%.Lycium chinense glycopeptide is brown ceramic powder, odorless, draw it is wet, it is soluble easily in water, mainly by four kinds of polysaccharide and more
The conjugate of peptide forms.Molecular weight is between 20000~200000 dalton.It is adapted to hypoimmunity crowd, can be improved
Immunity, antifatigue and anti-aging.Also nonalcoholic fatty liver and chronic hepatitis B be can treat.Memory can also be improved
With learning ability or mobility etc..Hermetically drying is needed to save.Shelf-life is 24 months.In addition, the medicine in the embodiment of the present application
Object includes: health care product, special diet, drug etc., in addition, the Lycium chinense glycopeptide in the embodiment of the present application can also be fabricated to food.
It, can also be by the pure of extraction particularly as being oral class medicine object can be made in the purity of extraction Lycium chinense glycopeptide up to standard
It spends Lycium chinense glycopeptide up to standard and injection class drug is made, associated patient is realized by the oral class medicine object or injection class drug to itself
The treatment of related disease can avoid the occurrence of uncomfortable situation.In practical applications, it is contemplated that the convenience of patient used,
Preferably, oral class medicine object can be fabricated to the drug of capsule shape or tablet shape or oral solution posture；Wherein, every capsule
Object 30-100mg containing Lycium chinense glycopeptide, the drug of every tablet class drug 30-100mg containing Lycium chinense glycopeptide, oral solution posture contain fructus lycii
Glycopeptide 30-100mg.Preferably, every class injection class drug contains Lycium chinense glycopeptide 30-100mg.Injection class drug can pass through adaptation
Injection injected.The Lycium chinense glycopeptide of 30-100mg can be absorbed for one day in adult.Lycium chinense glycopeptide passes through cellular immunity and body
Two kinds of approach, which are immunized, in liquid can stimulate human immune system, achieve the effect that improve immunity.It is found by mouse experiment, mouse
When oral dosage 1-2mg/Kg, lymphopoiesis can be remarkably promoted, enhance the phagocytic function of macrophage and improves blood
Clear hemolysin level.Its activity intensity 1-2 order of magnitude more eager to excel in whatever one does than the immunocompetence of general plant polyose.10 μ g/ of Lycium chinense glycopeptide
LDL inhibiting rate is up to 80% or more under ml concentration.The effect of angiogenesis inhibiting group effect, pharmacological evaluation is presented in Lycium chinense glycopeptide
The result shows that Lycium chinense glycopeptide can be by vascular endothelial cell Cell-Cycle Blockade in the G0-G1 phase, to press down within the scope of 5-40 μ g/ml
The effect of DNA synthesis and cell division proliferation processed.Lycium chinense glycopeptide can activate the expression of mouse boosting cell Nuclear factor NF-KB,
The metabolic activity of beta Cell of islet can be improved.
For details, reference can be made to the prior art, the present invention herein and is not construed as limiting the extraction process of Lycium chinense glycopeptide.
This application discloses a kind of application of Lycium chinense glycopeptide in immunity, anti-aging and memory drug, can will mention
Oral class is made in the purity taken Lycium chinense glycopeptide up to standard, and is existed in powdered mode, and associated patient can pass through
Using the drug containing Lycium chinense glycopeptide, drug herein includes food, health care product, special diet and drug etc., which can
To improve autoimmunity, resistance aging and the memory situation of itself be adjusted.It can be that one kind is clinically provided
New drug.
Fig. 1 is a kind of Lycium chinense glycopeptide tableting processes flow chart provided by the embodiment of the present invention, as shown in Figure 1, above-mentioned
On the basis of embodiment, Lycium chinense glycopeptide is made tablet class drug and specifically included by preferably embodiment:
S101: weighed auxiliary material is crushed so that auxiliary material is in powdered by pulverizer.
S102: Lycium chinense glycopeptide and powdered auxiliary material are carried out to proportion in proportion and obtain target material, target material is transported
It send between granulation, and after charging barrel is added in target material, opens equipment, the target component of adjustment equipment, until target material
It is in granular form.
S103: by molding particle by oven drying, the moisture of particle is made to be less than or equal to 5%.
S104: after mixing by all particles investment mixing machine after drying, pack tying is sent to intermediate station.
S105: in the case where external environment meets the requirements, the pack particle feeding in intermediate station is entered into charging barrel and is carried out
Compressing tablet process is to obtain tablet class drug.
Preferably, target component includes stirring frequency and chopping frequency.
Specifically, when all particles put into mixing machine after mixing, needing to set incorporation time as 20min, revolving speed is
20HZ, it is to be mixed uniformly after, discharging, pack tying, hand over intermediate station, and fill in time production operation record.
Preferably, the pack particle feeding in intermediate station is entered into charging barrel and carries out compressing tablet process to show that tablet class drug has
Body includes: to suppress the first preset time in the state that tabletting speed is less than or equal to 200,000 tablets hs, pressure is 10-30KN；
It is less than or equal to 1% more than or equal to 4kgf, friability when average slice weight is greater than or equal to 0.8g, hardness, and be not present and be broken,
After cracking and the piece crushed, adjusting the tabletting speed is re-compacted second preset time after ten thousand tablets h of 18-25 until obtaining
Until satisfactory tablet class drug.
Specifically, need first to check the whether intact cleaning of equipment before tabletting, whether mold is correct, and whether temperature and humidity environment fits
Whether then title, quantity, lot number that combined pressure piece gets material from intermediate station, and checks material etc. be accurate, and material feeding is entered
Charging barrel adjusts tabletting speed≤200,000 tablets hs, pressure 10-30KN under lower-speed state.To slice weight (tablet weight variation: average piece
Weight ± 3%, average slice weight >=0.8g), hardness (>=4kgf), friability (≤1%, and fracture, cracking and crushing must not be detected
Piece) etc. meet technique require after formally start ten thousand tablets h of tabletting speed 18-25.When normal sheeting operation, the detection lug method of double differences
Different, hardness, friability, appearance, and relevant parameter is recorded, operator needs wearing gloves when operating, and naked hand is not allowed directly to connect
Touch material, unsuitable direct tying after tabletting pack, should after piece cools down tying again, and carry out mark and hand over intermediate station, do in time
Good operation note.
Preferably, after obtaining satisfactory tablet class drug, further includes: again to satisfactory tablet class drug
Secondary progress quality review confirmation.Preferably, after carrying out quality review confirmation again to satisfactory tablet class drug, also
It include: to superscribe required color and date of manufacture for the tablet class drug of requisite quality.
Specifically, material to be packaged is got from intermediate station according to batch packaging directive, checks the name of an article, lot number, quantity, quality shape
State etc., from interior packaging material is got between interior packaging material, the verification name of an article, number, lot number, producer, quantity, quality state etc. will after meeting regulation
Interior packaging material is transferred to interior parlor, the pouch of dimension is used by packaging directive, and checked and confirmed by QA, carries out operation note in time
Record.Then, the piece attached bag for receiving intermediate products inspection report is wrapped to required color.By batch packaging directive from warehouse
Get carton etc., and check quantity, specification, the name of an article, print content etc..Carton first prints lot number, production date according to batch packaging directive
The contents such as phase, first carton must be checked by QA to be confirmed, first prints the 90% of batch, residue is according to actual quantity reprinting.Then
Lot number, date of manufacture are set by batch packaging directive, and is checked and is confirmed by QA, finally with interior packet on line, cases, puts by 20 box one case
Enter the quality certification of QA granting, sealing is packaged.When production by QA sample detection, keep sample, damaged packaging material in production collects numeration, and
It keeps a record and calculates material balance.
Those skilled in the art will readily occur to its of the application after considering specification and practicing application disclosed herein
His embodiment.This application is intended to cover any variations, uses, or adaptations of the application, these modifications, purposes or
Person's adaptive change follow the general principle of the application and include common knowledge in the art disclosed in the present application or
Conventional techniques.Description and embodiments are considered only as exemplary, and the just true range of the application is pointed out by claim.
It should be understood that the application is not limited to the precise structure that has been described above and shown in the drawings, and
And various modifications and changes may be made without departing from the scope thereof.Above-described the application embodiment is not constituted to this Shen
Please protection scope restriction.
Claims (8)
1. a kind of application of Lycium chinense glycopeptide in immunity, anti-aging and memory drug characterized by comprising
Oral class medicine object or injection class drug is made in the purity of extraction Lycium chinense glycopeptide up to standard.
2. application of the Lycium chinense glycopeptide according to claim 1 in immunity, anti-aging and memory drug, feature exist
In the oral class medicine object includes the drug of capsule class drug or tablet class drug or oral solution posture；
Wherein, every capsule class drug contains the Lycium chinense glycopeptide 30-100mg, and every tablet class drug contains the Lycium chinense glycopeptide 30-
The drug of 100mg, oral solution posture contain the Lycium chinense glycopeptide 30-100mg.
3. application of the Lycium chinense glycopeptide according to claim 2 in immunity, anti-aging and memory drug, feature exist
In the tablet class drug is made in the Lycium chinense glycopeptide and is specifically included:
Weighed auxiliary material is crushed so that the auxiliary material is in powdered by pulverizer；
The Lycium chinense glycopeptide and powdered auxiliary material are carried out to proportion in proportion and obtain target material, the target material is transported
To between granulation, and after charging barrel is added in the target material, equipment is opened, the target component of the equipment is adjusted, until institute
Target material is stated to be in granular form；
By molding particle by oven drying, the moisture of the particle is made to be less than or equal to 5%；
After mixing by all particles investment mixing machine after drying, pack tying is sent to intermediate station；
In the case where external environment meets the requirements, the pack particle feeding in the intermediate station is entered into charging barrel and is carried out at tabletting
Reason is to obtain the tablet class drug.
4. application of the Lycium chinense glycopeptide according to claim 3 in immunity, anti-aging and memory drug, feature exist
In the target component includes stirring frequency and chopping frequency.
5. application of the Lycium chinense glycopeptide according to claim 3 in immunity, anti-aging and memory drug, feature exist
In the pack particle feeding by the intermediate station enters charging barrel and carries out compressing tablet process to obtain the tablet class drug tool
Body includes:
The first preset time is suppressed in the state that tabletting speed is less than or equal to 200,000 tablets hs, pressure is 10-30KN；
When average slice weight is greater than or equal to 0.8g, hardness is greater than or equal to 4kgf, friability is less than or equal to 1%, and is not present
After the piece of fracture, cracking and crushing, it is straight for re-compacted second preset time after ten thousand tablets h of 18-25 to adjust the tabletting speed
Until obtaining satisfactory tablet class drug.
6. application of the Lycium chinense glycopeptide according to claim 5 in immunity, anti-aging and memory drug, feature exist
In, it is described obtain satisfactory tablet class drug after, further includes:
Quality review confirmation is carried out again to the satisfactory tablet class drug.
7. application of the Lycium chinense glycopeptide according to claim 6 in immunity, anti-aging and memory drug, feature exist
In, it is described the satisfactory tablet class drug is carried out again quality review confirmation after, further includes:
Required color and date of manufacture are superscribed for the tablet class drug of requisite quality.
8. application of the Lycium chinense glycopeptide according to claim 1 in immunity, anti-aging and memory drug, feature exist
In injection class drug described in every class contains the Lycium chinense glycopeptide 30-100mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910003488.6A CN109498800A (en) | 2019-01-03 | 2019-01-03 | Application of the Lycium chinense glycopeptide in immunity, anti-aging and memory drug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910003488.6A CN109498800A (en) | 2019-01-03 | 2019-01-03 | Application of the Lycium chinense glycopeptide in immunity, anti-aging and memory drug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109498800A true CN109498800A (en) | 2019-03-22 |
Family
ID=65756109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910003488.6A Pending CN109498800A (en) | 2019-01-03 | 2019-01-03 | Application of the Lycium chinense glycopeptide in immunity, anti-aging and memory drug |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109498800A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112843221A (en) * | 2021-02-01 | 2021-05-28 | 宁夏杞肽科技有限公司 | Application of pharmaceutical composition in preparation of medicine for treating subliminal depression |
| CN113413455A (en) * | 2021-06-28 | 2021-09-21 | 宁夏农林科学院动物科学研究所(宁夏草畜工程技术研究中心) | Immunity enhancing composition and application thereof |
| CN113616770A (en) * | 2021-08-10 | 2021-11-09 | 宁夏杞肽科技有限公司 | Use of a pharmaceutical mixture for the treatment or prevention of a disease caused by a coronavirus |
| CN114209810A (en) * | 2022-01-06 | 2022-03-22 | 宁夏杞肽科技有限公司 | Application of lycium barbarum glycopeptide in preparation of medicine for preventing or treating inflammatory bowel disease |
| WO2023071187A1 (en) * | 2021-10-26 | 2023-05-04 | 宁夏杞肽科技有限公司 | Use of fructus lycii glucopeptide |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102228508A (en) * | 2011-06-17 | 2011-11-02 | 青阳县杰灵生物工程有限责任公司 | Method for preparing compound salvia miltiorrhiza tablets |
| CN102416004A (en) * | 2011-12-08 | 2012-04-18 | 扬子江药业集团广州海瑞药业有限公司 | Glimepiride tablets and preparation method thereof |
| CN103637268A (en) * | 2013-12-25 | 2014-03-19 | 山东阿如拉药物研究开发有限公司 | Instant medlar sea sedge with function of improving memory |
| CN103690926A (en) * | 2013-09-10 | 2014-04-02 | 中国人民解放军军事经济学院 | Application of medlar polysaccharide to resistance to sleep deprivation stress damage |
| CN104784050A (en) * | 2014-01-17 | 2015-07-22 | 南京瑞尔医药有限公司 | Preparation method for gliclazide tablet composition |
| CN107021995A (en) * | 2016-01-29 | 2017-08-08 | 中国科学院上海有机化学研究所 | A kind of Lycium chinense glycopeptide and its preparation method and application |
| CN108567759A (en) * | 2018-07-26 | 2018-09-25 | 北京百奥药业有限责任公司 | A kind of valsartan and Hydrochlorothiade piece and preparation method thereof |
| CN108653324A (en) * | 2018-06-26 | 2018-10-16 | 海南金贝康制药有限公司 | One kind of multiple vitamin calcium zinc chewable tablets and its manufacturing method |
-
2019
- 2019-01-03 CN CN201910003488.6A patent/CN109498800A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102228508A (en) * | 2011-06-17 | 2011-11-02 | 青阳县杰灵生物工程有限责任公司 | Method for preparing compound salvia miltiorrhiza tablets |
| CN102416004A (en) * | 2011-12-08 | 2012-04-18 | 扬子江药业集团广州海瑞药业有限公司 | Glimepiride tablets and preparation method thereof |
| CN103690926A (en) * | 2013-09-10 | 2014-04-02 | 中国人民解放军军事经济学院 | Application of medlar polysaccharide to resistance to sleep deprivation stress damage |
| CN103637268A (en) * | 2013-12-25 | 2014-03-19 | 山东阿如拉药物研究开发有限公司 | Instant medlar sea sedge with function of improving memory |
| CN104784050A (en) * | 2014-01-17 | 2015-07-22 | 南京瑞尔医药有限公司 | Preparation method for gliclazide tablet composition |
| CN107021995A (en) * | 2016-01-29 | 2017-08-08 | 中国科学院上海有机化学研究所 | A kind of Lycium chinense glycopeptide and its preparation method and application |
| CN108653324A (en) * | 2018-06-26 | 2018-10-16 | 海南金贝康制药有限公司 | One kind of multiple vitamin calcium zinc chewable tablets and its manufacturing method |
| CN108567759A (en) * | 2018-07-26 | 2018-09-25 | 北京百奥药业有限责任公司 | A kind of valsartan and Hydrochlorothiade piece and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 徐顺霖等: "枸杞糖肽对缺氧及KCl诱导的心肌细胞钙超载的影响", 《中国中药杂志》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112843221A (en) * | 2021-02-01 | 2021-05-28 | 宁夏杞肽科技有限公司 | Application of pharmaceutical composition in preparation of medicine for treating subliminal depression |
| CN113413455A (en) * | 2021-06-28 | 2021-09-21 | 宁夏农林科学院动物科学研究所(宁夏草畜工程技术研究中心) | Immunity enhancing composition and application thereof |
| CN113413455B (en) * | 2021-06-28 | 2023-02-14 | 宁夏农林科学院动物科学研究所(宁夏草畜工程技术研究中心) | Immunity enhancing composition and application thereof |
| CN113616770A (en) * | 2021-08-10 | 2021-11-09 | 宁夏杞肽科技有限公司 | Use of a pharmaceutical mixture for the treatment or prevention of a disease caused by a coronavirus |
| WO2023071187A1 (en) * | 2021-10-26 | 2023-05-04 | 宁夏杞肽科技有限公司 | Use of fructus lycii glucopeptide |
| CN114209810A (en) * | 2022-01-06 | 2022-03-22 | 宁夏杞肽科技有限公司 | Application of lycium barbarum glycopeptide in preparation of medicine for preventing or treating inflammatory bowel disease |
| CN114209810B (en) * | 2022-01-06 | 2023-02-07 | 宁夏杞肽科技有限公司 | Application of lycium barbarum glycopeptide in preparation of medicine for preventing or treating inflammatory bowel disease |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109498800A (en) | Application of the Lycium chinense glycopeptide in immunity, anti-aging and memory drug | |
| CN104257887B (en) | A kind of composition for promoting lead discharging and its application | |
| CN102228176A (en) | Composition for increasing immunity and its preparation method | |
| CN105661512B (en) | A kind of fruit ferment particle and its preparation technology | |
| CN101926891A (en) | Composition for losing weight | |
| CN103583751A (en) | Polygonatum rhizome granular health tea and its preparation method | |
| CN104922167A (en) | Ganoderma lucidum spore powder electuary and preparation method thereof | |
| CN104432063B (en) | Composition for alleviating athletic fatigue and preparation method thereof | |
| CN100556429C (en) | A kind of pharmaceutical composition that contains Fructus Vitis viniferae extract and preparation method thereof, purposes | |
| CN101912110B (en) | Composite with effects of losing weight and lowering blood sugar and blood lipid | |
| CN104738716B (en) | Food therapeutic composition for rhinitis, tracheitis or asthma and preparation method thereof | |
| CN107048388B (en) | A kind of nourishing the stomach food agent | |
| CN106174484A (en) | There is the enzyme composition of cough and asthma relieving efficacy, effervescent granule and preparation method | |
| CN100348229C (en) | Capsule prepn for treating laryngopharyngitis and tonsillitis and its prepn process | |
| CN101972297A (en) | Liver health tablet | |
| CN102309537B (en) | Anti-fatigue and immunity-enhancing Chinese medicinal composition, its preparation method and application | |
| CN102293970A (en) | Special Chinese patent medicine for resisting phthisis-astragalus fritillaria capsules | |
| CN103190507A (en) | Food health tea electuary capable of protecting gastric mucosa | |
| CN106822008A (en) | A kind of vitamin D dissolution formulation and preparation method thereof | |
| CN113425697A (en) | Preparation and preliminary pharmaceutical evaluation method of compound qi-tonifying intestine-moistening capsule | |
| CN113598267A (en) | Preparation process of hyaluronic acid pet health product | |
| CN109090602A (en) | A kind of health food of strengthen immunity and its application | |
| CN106035850A (en) | Poria cocos-trichosahthes kirilowii maxin health tea and preparation process thereof | |
| CN101653542A (en) | Medicinal composition for treating acute and chronic bronchitis and preparation method | |
| CN103749781A (en) | Rhodiola rosea and ginseng oolong tea capable of tonifying liver and kidney, keeping health and shaping |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190322 |
|
| RJ01 | Rejection of invention patent application after publication |