CN109491066A - Full-automatic micro- scanning device - Google Patents

Full-automatic micro- scanning device Download PDF

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Publication number
CN109491066A
CN109491066A CN201811614908.6A CN201811614908A CN109491066A CN 109491066 A CN109491066 A CN 109491066A CN 201811614908 A CN201811614908 A CN 201811614908A CN 109491066 A CN109491066 A CN 109491066A
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CN
China
Prior art keywords
lifting
traversing
component
driving
full
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Granted
Application number
CN201811614908.6A
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Chinese (zh)
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CN109491066B (en
Inventor
梁光明
殷星星
刘济群
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Hunan Friend Technology Co Ltd
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Hunan Friend Technology Co Ltd
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Priority to CN201811614908.6A priority Critical patent/CN109491066B/en
Publication of CN109491066A publication Critical patent/CN109491066A/en
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036Scanning details, e.g. scanning stages
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/32Micromanipulators structurally combined with microscopes

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

The present invention provides a kind of full-automatic micro- scanning devices, it include: bearing seat, driving assembly and automatic microscopy component, driving assembly includes going up and down out box component, lifting receipts box component and the traversing component of fragment, it is described that go up and down out box component and the lifting to receive box component include fixing seat, lifting guide plate, lifting actuator, the lifting actuator includes that lifting driving motor, lifting conveyer belt and lifting box, the specimen slide are set in the lifting box;The traversing component of fragment includes support base, traversing fixed link and traversing actuator, and the traversing actuator includes traversing driving motor, traversing conveyer belt and driving baffle, and the automatic microscopy component includes micrometron and limit base.The present invention is by carrying out the driving of the loading and unloading of specimen slide automatically, scanning the driving and automatically scanning of station, scan efficiency is improved, is effectively prevented as using manually progress loading and unloading driving, scanning the low problem of scan efficiency caused by the driving of station.

Description

Full-automatic micro- scanning device
Technical field
The present invention relates to medical equipment technological field, in particular to a kind of full-automatic micro- scanning device.
Background technique
Microscope plays an important role in pathologic finding, either does cell pathology or histopathology, and doctor needs Glass slide is made in corresponding sample and is dyed, microscopically observation is subsequently placed in and draws a conclusion.Traditional artificial diagosis side Method brings onerous toil to doctor, and be easy to cause mistaken diagnosis.In recent years, with automation equipment, intelligentized development, Micrometron technology starts to occur and rapidly develop.The technology controls microscope by computer and automatically snaps under clearly mirror Image lists abnormal cell after then carrying out analysis identification.It is automatically controlled due to introducing, this technology can assist a physician, have Effect reduces the working strength of doctor, improves the diagnostic accuracy of doctor.
In existing slide scanning device use process, glass slide is manually put into micrometron by staff In, glass slide is manually taken out by staff again after the completion of microscopy, this kind of mode only realize it is microscopical focus, scanning Automation, the loading and unloading process of glass slide is manual operation, reduces the scan efficiency of slide scanning device.
Summary of the invention
Based on this, the present invention provides a kind of full-automatic micro- scanning device, for solving in the prior art due to using hand It is dynamic to carry out the low problem of scan efficiency caused by glass slide feeding, blanking.
In a first aspect, the present invention provides a kind of full-automatic micro- scanning device, it is automatic for being carried out to specimen slide Scanning, comprising: bearing seat and the driving assembly being respectively arranged on the bearing seat and automatic microscopy component, the driving component packet It includes and goes up and down out box component, box component is received in lifting and goes up and down out box component and the fragment gone up and down between receipts box component set on described Traversing component, it is described go up and down out box component and the lifting and receive box component include fixing seat and be respectively arranged in the fixing seat Lifting guide plate, lifting actuator, the lifting actuator includes going up and down driving motor, connecting with the lifting driving motor Lifting conveyer belt and the lifting box with the lifting and driving band connection, the specimen slide be set to the lifting box in;
The traversing component of fragment includes support base, the traversing fixed link connecting with the support base and is set to described traversing Traversing actuator in fixed link, the traversing actuator include traversing driving motor, connect with the traversing driving motor Traversing conveyer belt and the driving baffle on the traversing conveyer belt, the driving baffle are used for the institute in the lifting box State specimen slide carry out it is laterally driven, the automatic microscopy component includes micrometron and connect with the micrometron Limit base, the limit base is for fixing the specimen slide.
Above-mentioned full-automatic micro- scanning device is effectively raised by the design of the limit base to specimen slide Clamping effect mentioned with preventing the micrometron mobile to the position of specimen slide in specimen slide scanning process The high scanning precision of the full-automatic micro- scanning device, passes through the design of the lifting actuator, effective to ensure Driving to the automatic loading/unloading of specimen slide has effectively been ensured and has been carried to sample by the design of the traversing actuator The driving of the automatic cross of slide, so that automatically by the traversing extremely scanning station of specimen slide, and when the micrometron is complete After the scanning of paired samples glass slide, box component is received into the specimen slide lifting, to complete to receive box step, Above-mentioned full-automatic micro- scanning device by carry out automatically the driving of the loading and unloading of specimen slide, scan station driving and from Dynamic scanning, improves scan efficiency, effectively prevents due to using the drive for manually carrying out loading and unloading driving, scanning station The low problem of scan efficiency caused by dynamic.
Further, the full-automatic micro- scanning device further includes positioning component, and the positioning component includes being set to institute It states the charging alignment sensor on support base and the micro- alignment sensor in the traversing fixed link and discharging positioning passes Sensor.
Further, the fixing seat include fixed station and with fixed station fixed plate connected vertically, the fixation One end of plate towards the lifting driving motor is equipped with limit hole, and the output shaft of the lifting driving motor runs through the limit Hole, the fixed plate are equipped with limit shaft backwards to one end of the lifting driving motor, and the lifting conveyer belt is set in the limit On the axis of position.
Further, the limit base includes limiting stand, the plummer being slidably connected with the limiting stand and is set to described Limit plate on plummer, the limit plate are equipped with limit sliding chutes, and the two sides of the limit sliding chutes are equipped with multiple barrier plates, institute The limit that limit sliding chutes are stated for the specimen slide is slided.
Further, the support base include support rod and with supporting bar top extension board connected vertically, it is described The end of extension board is vertical with the traversing fixed link to be connect.
Further, the discharging alignment sensor is set to the top that box component is received in the lifting, and the micro- positioning passes Sensor is set to the top of the micrometron.
Further, the positioning component further includes a processor, the processor with the lifting driving motor, institute It is electrical to state traversing driving motor, the charging alignment sensor, the micro- alignment sensor and the discharging alignment sensor Connection.
Further, the side wall of the bearing seat is equipped with control panel, and the control panel is equipped with multiple communication ends Mouthful, the communication port is electrically connected with the processor, the micrometron respectively.
Further, the bearing seat is equipped with fastening plate, and the fastening plate is equipped with engaging slot, the micrometron End be connected in the engaging slot.
Further, discharging driving plate, the discharging driving plate and the lifting driving motor are equipped in the lifting box Output shaft be connected.
Detailed description of the invention
Fig. 1 is the structural schematic diagram for the full-automatic micro- scanning device that first embodiment of the invention provides;
Fig. 2 is the structure schematic diagram of full-automatic micro- scanning device in Fig. 1;
Fig. 3 is the structural schematic diagram of driving assembly in Fig. 1;
Fig. 4 is the structure schematic diagram of driving assembly in Fig. 3;
Fig. 5 is the structural schematic diagram in Fig. 3 at A;
Fig. 6 is the structural schematic diagram of automatic microscopy component in Fig. 1;
Fig. 7 is the structural schematic diagram of limit base in Fig. 6;
Fig. 8 is the structural schematic diagram for the positioning component that second embodiment of the invention provides;
Specific embodiment
To keep the purposes, technical schemes and advantages of embodiment of the present invention clearer, implement below in conjunction with the present invention The technical solution in embodiment of the present invention is clearly and completely described in attached drawing in mode, it is clear that described reality The mode of applying is some embodiments of the invention, rather than whole embodiments.Based on the embodiment in the present invention, ability Domain those of ordinary skill every other embodiment obtained without creative efforts, belongs to the present invention The range of protection.Therefore, the detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit below and is wanted The scope of the present invention of protection is sought, but is merely representative of selected embodiment of the invention.Based on the embodiment in the present invention, Every other embodiment obtained by those of ordinary skill in the art without making creative efforts belongs to this Invent the range of protection.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ", " thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside", " up time The orientation or positional relationship of the instructions such as needle ", " counterclockwise " is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of The description present invention and simplified description, rather than the equipment of indication or suggestion meaning or element must have a particular orientation, with spy Fixed orientation construction and operation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or Implicitly include one or more of the features.In the description of the present invention, the meaning of " plurality " is two or more, Unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc. Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral;It can be mechanical connect It connects, is also possible to be electrically connected;It can be directly connected, can also can be in two elements indirectly connected through an intermediary The interaction relationship of the connection in portion or two elements.It for the ordinary skill in the art, can be according to specific feelings Condition understands the concrete meaning of above-mentioned term in the present invention.
In the present invention unless specifically defined or limited otherwise, fisrt feature second feature "upper" or "lower" It may include that the first and second features directly contact, also may include that the first and second features are not direct contacts but pass through it Between other characterisation contact.Moreover, fisrt feature includes the first spy above the second feature " above ", " above " and " above " Sign is right above second feature and oblique upper, or is merely representative of first feature horizontal height higher than second feature.Fisrt feature exists Second feature " under ", " lower section " and " following " include that fisrt feature is directly below and diagonally below the second feature, or is merely representative of First feature horizontal height is less than second feature.
Fig. 1 to Fig. 2 is please referred to, is that the structure for the full-automatic micro- scanning device 100 that first embodiment of the invention provides is shown It is intended to, for carrying out automatically scanning to specimen slide 101, comprising: bearing seat 10 and be respectively arranged on the bearing seat 10 Driving assembly and automatic microscopy component 50, by the design of the bearing seat 10, effectively to the driving component and it is described from Index glass inspection component 50 plays the fixed effect of carrying, and it is integrally-built steady to improve the full-automatic micro- scanning device 100 Qualitative, the driving component is for driving the loading and unloading of specimen slide 101 automatically and going Winter Solstice to scan specimen slide 101 Station, to facilitate automatic focusing and scanning of the automatic microscopy component 50 to specimen slide 101.
Specifically, please referring to Fig. 3 to Fig. 5, the driving component includes going up and down out box component 20, lifting receipts 30 and of box component It is described to go up and down out box portion set on the traversing component 40 of fragment gone up and down out between box component 20 and the lifting receipts box component 30 After part 20 is for carrying specimen slide 101 in advance, by driving specimen slide 101 to be moved to discharging station, to realize sample The self-emptying of this glass slide 101 operates, and the lifting receives box component 30 and is used to carry sample when the automatic microscopy component 50 Slide 101 is loaded it after completing scanning, and to be automatically performed the operation of the rewinding to specimen slide 101, the fragment is horizontal Component 40 is moved to be used to that it to be carried out transverse direction towards the automatic microscopy component 50 when specimen slide 101 is in discharging station Driving, until by the driving of specimen slide 101 to microscopy station, and when the automatic microscopy component 50 is completed to specimen slide It is when 101 scanning, specimen slide 101 is laterally driven to discharging station, to facilitate the lifting to receive box component 30 to sample The draw operation of glass slide 101.
Preferably, it is described box component 20 and the lifting is gone up and down out to receive box component 30 include fixing seat and be respectively arranged on institute State the lifting guide plate 22 in fixing seat, lifting actuator is effectively oriented to the lifting by the design of the fixing seat Plate 22 and the lifting actuator play the fixed effect of carrying, improve and described go up and down out box component 20 and lifting receipts The integrally-built stability of box component 30 is effectively gone up and down in the lifting actuator by the design of the lifting guide plate 22 Guiding role is played in the process, and the lifting actuator carries out specimen slide 101 for realizing automatic lifting, to control Charging and draw operation, the lifting actuator include the liter for going up and down driving motor 23, connecting with the lifting driving motor 23 Conveyer belt 26 and the lifting box 24 with the lifting and driving band connection drop, and the specimen slide 101 is set to the lifting box 24 Interior, when the lifting driving motor 23 work, the lifting box 24 is under the drive of the lifting and driving band, to carry to sample Slide 101 carries out carrying driving up and down.
In the present embodiment, the traversing component 40 of fragment includes support base, the traversing fixed link connecting with the support base 44 and the traversing actuator in the traversing fixed link 44, by the design of the support base, effectively to described traversing Fixed link 44 and the traversing actuator play the fixed effect of carrying, improve traversing 40 overall structure of component of the fragment Stability, further, the traversing fixed link 44 is for carrying the traversing actuator, and the traversing actuator is for driving The transverse shifting of dynamic specimen slide 101, the traversing actuator include traversing driving motor 43 and the traversing driving motor 43 connection traversing conveyer belts 45 and the driving baffle 46 on the traversing conveyer belt 45, the driving baffle 46 be used for pair The specimen slide 101 in the lifting box 24 carries out laterally driven.
Please refer to Fig. 6 to Fig. 7, the automatic microscopy component 50 include micrometron 51 and with the micrometron 51 The limit base 52 of connection, for fixing to the specimen slide 101, the limit base 52 wraps the limit base 52 Include limiting stand 53, the plummer 54 being slidably connected with the limiting stand 53 and the limit plate 55 on the plummer 54, institute Limit plate 55 is stated equipped with limit sliding chutes, the two sides of the limit sliding chutes are equipped with multiple barrier plates 56, and the limit sliding chutes are used for The limit of the specimen slide 101 is slided, and the barrier plate 56 is used to grip specimen slide 101, to prevent Position during only specimen slide 101 is scanned is mobile, the support base include support rod 41 and with the support rod 41 Top extension board 42 connected vertically, the end of the extension board 42 is vertical with the traversing fixed link 44 to be connect.
The fixing seat include fixed station 21 and with the fixed station 21 fixed plate 25 connected vertically, the fixed plate 25 It is equipped with limit hole towards one end of the lifting driving motor 23, the output shaft of the lifting driving motor 23 runs through the limit Hole, the fixed plate 25 are equipped with limit shaft backwards to one end of the lifting driving motor 23, and the lifting conveyer belt 26 is set in On the limit shaft, by the limit shaft design, the fixed effect of limit effectively is played to the lifting conveyer belt 26 Fruit has ensured that the lifting conveyer belt 26 drives upside down the lifting box 24 and specimen slide 101.
It should be noted that the bearing seat 10 is equipped with fastening plate 11 in the present embodiment, the fastening plate 11 is equipped with The end of engaging slot, the micrometron 51 is connected in the engaging slot, passes through the fastening plate 11 and the engaging slot Design, effectively raise the stability of structure between the bearing seat 10 and the micrometron 51, the lifting box Discharging driving plate is equipped in 24, the discharging driving plate is connected with the output shaft of the lifting driving motor 23.
In the present embodiment, by the design of the limit base 52, the effect of the clamping to specimen slide 101 is effectively raised Fruit is mentioned with preventing the micrometron 51 mobile to the position of specimen slide 101 in 101 scanning process of specimen slide The high scanning precision of the full-automatic micro- scanning device 100, passes through the design of the lifting actuator, effective to ensure The driving of the automatic loading/unloading of specimen slide 101 effectively ensured by the design of the traversing actuator to sample The driving of the automatic cross of this glass slide 101, so that automatically by the traversing extremely scanning station of specimen slide 101, and described in certainly After dynamic microscope 51 is completed to the scanning of specimen slide 101, box portion is received into the lifting of specimen slide 101 Part 30, to complete to receive box step, above-mentioned full-automatic micro- scanning device 100 by carry out automatically specimen slide 101 up and down The driving of material, the driving and automatically scanning for scanning station, improve scan efficiency, effectively prevent due to using manually It carries out loading and unloading driving, scan the low problem of scan efficiency caused by the driving of station.
Referring to Fig. 8, the structural schematic diagram of the positioning component provided for second embodiment of the invention, the second embodiment with The structure of first embodiment is more or less the same, and difference is, in the present embodiment, the full-automatic micro- scanning device 100 is also wrapped Positioning component is included, the positioning component includes the charging alignment sensor 61 on the support base and is set to described traversing solid Micro- alignment sensor 63 and discharging alignment sensor 62 in fixed pole 44, the charging alignment sensor 61 is for detecting sample Difference in height between the position and feed station of glass slide 101, the micro- alignment sensor 63 is for detecting specimen slide Poor location between 101 position and limit station, the discharging alignment sensor 62 are used to detect the position of specimen slide 101 With the difference in height between discharging station, wherein the discharging alignment sensor 62 is set to the top that box component 30 is received in the lifting, The micro- alignment sensor 63 is set to the top of the micrometron 51.
Further, the positioning component further includes a processor 60, and the processor 60 drives electricity with the lifting Machine 23, the traversing driving motor 43, the charging alignment sensor 61, the micro- alignment sensor 63 and it is described go out anticipate Level sensor 62 is electrically connected, and the processor 60 is for receiving the charging alignment sensor 61, the micro- orientation sensing The detected value of device 63 and the charging alignment sensor 61, and judge whether the detected value is less than distance threshold respectively, if so, The corresponding control of processor 60 carries out the switching control of the lifting driving motor 23 and 43 working condition of traversing driving motor, The side wall of the bearing seat 10 is equipped with control panel, and the control panel is equipped with multiple communication port, the communication port It is electrically connected respectively with the processor 60, the micrometron 51.
In the present embodiment, by the design of the positioning component, effectively to the charging, discharging, scanning of specimen slide 101 Step plays locating effect, the positioning accuracy of the full-automatic micro- scanning device 100 is improved, so as to further mention The high working efficiency of the full-automatic micro- scanning device 100.
Above embodiment described technical principles of the invention, and the description is merely to explain the principles of the invention, and It cannot be construed to the limitation of the scope of the present invention in any way.Based on the explanation herein, those skilled in the art is not required to Other specific embodiments of the invention can be associated by paying creative labor, these modes fall within of the invention In protection scope.

Claims (10)

1. a kind of full-automatic micro- scanning device, for carrying out automatically scanning to specimen slide characterized by comprising hold The driving assembly and automatic microscopy component for carrying seat and being respectively arranged on the bearing seat, the driving component include going up and down out box portion Part, lifting receive box component and set on the traversing component of fragment gone up and down out between box component and the lifting receipts box component, institutes Stating and going up and down out box component and the lifting receipts box component includes fixing seat and the lifting being respectively arranged in fixing seat guiding Plate, lifting actuator, the lifting actuator include the lifting transmission for going up and down driving motor, connecting with the lifting driving motor Band and lifting box with the lifting and driving band connection, the specimen slide are set in the lifting box;
The traversing component of fragment include support base, the traversing fixed link being connect with the support base and be set to the traversing fixation Traversing actuator on bar, the traversing actuator include traversing driving motor, connect with the traversing driving motor it is traversing Conveyer belt and the driving baffle on the traversing conveyer belt, the driving baffle are used for the sample in the lifting box This glass slide carries out laterally driven, and the automatic microscopy component includes micrometron and the limit that connect with the micrometron Position seat, the limit base is for fixing the specimen slide.
2. full-automatic micro- scanning device according to claim 1, which is characterized in that the full-automatic micro- scanning device It further include positioning component, the positioning component includes the charging alignment sensor on the support base and is set to described traversing Micro- alignment sensor and discharging alignment sensor in fixed link.
3. full-automatic micro- scanning device according to claim 1, which is characterized in that the fixing seat include fixed station and It is equipped with limit hole with one end of fixed station fixed plate connected vertically, the fixed plate towards the lifting driving motor, The output shaft of the lifting driving motor runs through the limit hole, and the fixed plate is set backwards to one end of the lifting driving motor There is limit shaft, the lifting conveyer belt is set on the limit shaft.
4. full-automatic micro- scanning device according to claim 1, which is characterized in that the limit base include limiting stand, The plummer and the limit plate on the plummer being slidably connected with the limiting stand, the limit plate are equipped with limit and slide Slot, the two sides of the limit sliding chutes are equipped with multiple barrier plates, and limit of the limit sliding chutes for the specimen slide is slided.
5. full-automatic micro- scanning device according to claim 1, which is characterized in that the support base include support rod and With supporting bar top extension board connected vertically, the end of the extension board is vertical with the traversing fixed link to be connect.
6. full-automatic micro- scanning device according to claim 2, which is characterized in that the discharging alignment sensor is set to The top of box component is received in the lifting, and the micro- alignment sensor is set to the top of the micrometron.
7. full-automatic micro- scanning device according to claim 2, which is characterized in that the positioning component further includes at one Manage device, the processor with the lifting driving motor, the traversing driving motor, the charging alignment sensor, described Micro- alignment sensor and the discharging alignment sensor are electrically connected.
8. full-automatic micro- scanning device according to claim 7, which is characterized in that the side wall of the bearing seat is equipped with Control panel, the control panel are equipped with multiple communication port, the communication port respectively with the processor, described automatic Microscope is electrically connected.
9. full-automatic micro- scanning device according to claim 1, which is characterized in that the bearing seat is equipped with engaging Plate, the fastening plate are equipped with engaging slot, and the end of the micrometron is connected in the engaging slot.
10. full-automatic micro- scanning device according to claim 1, which is characterized in that be equipped with discharging in the lifting box Driving plate, the discharging driving plate are connected with the output shaft of the lifting driving motor.
CN201811614908.6A 2018-12-27 2018-12-27 Full-automatic micro-scanning equipment Active CN109491066B (en)

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CN111692491A (en) * 2020-06-28 2020-09-22 程龙虎 Monitoring instrument lifting support
WO2022213648A1 (en) * 2021-04-09 2022-10-13 上海杏脉信息科技有限公司 Microscopic image scanning device and system

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CN206479543U (en) * 2017-01-20 2017-09-08 宁波司迈尔医疗科技有限公司 Full-automatic leukorrhea detector
CN108405352A (en) * 2018-01-31 2018-08-17 杭州智微信息科技有限公司 A kind of automation slide upper piece system
CN109030371A (en) * 2018-10-25 2018-12-18 赛恩斯科学仪器(广州)有限公司 A kind of automation slice scanning means and slice scanner

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CN104777027A (en) * 2015-03-25 2015-07-15 江苏硕世生物科技有限公司 Multifunctional full-automatic gram staining instrument
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Publication number Priority date Publication date Assignee Title
CN111692491A (en) * 2020-06-28 2020-09-22 程龙虎 Monitoring instrument lifting support
WO2022213648A1 (en) * 2021-04-09 2022-10-13 上海杏脉信息科技有限公司 Microscopic image scanning device and system

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