CN109415285A - 苯双酚衍生物及其制备方法和在医药上的应用 - Google Patents
苯双酚衍生物及其制备方法和在医药上的应用 Download PDFInfo
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- CN109415285A CN109415285A CN201780020377.5A CN201780020377A CN109415285A CN 109415285 A CN109415285 A CN 109415285A CN 201780020377 A CN201780020377 A CN 201780020377A CN 109415285 A CN109415285 A CN 109415285A
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- cyclopropylethyl
- pharmaceutically acceptable
- prodrug
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- acceptable salt
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/08—Quinones with polycyclic non-condensed quinoid structure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
本发明涉及苯双酚衍生物及其制备方法和在医药上的应用。本发明的苯双酚衍生物能够促进镇静催眠、脑保护，治疗和/或预防中枢神经系统相关的疾病。
Description
PCT国内申请，说明书已公开。
Claims (9)
- PCT国内申请，权利要求书已公开。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111220267.8A CN113801004A (zh) | 2016-05-13 | 2017-05-12 | 苯双酚衍生物及其制备方法和在医药上的应用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2016103171788 | 2016-05-13 | ||
| CN201610317178 | 2016-05-13 | ||
| PCT/CN2017/084076 WO2017193986A1 (zh) | 2016-05-13 | 2017-05-12 | 苯双酚衍生物及其制备方法和在医药上的应用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111220267.8A Division CN113801004A (zh) | 2016-05-13 | 2017-05-12 | 苯双酚衍生物及其制备方法和在医药上的应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109415285A true CN109415285A (zh) | 2019-03-01 |
| CN109415285B CN109415285B (zh) | 2021-12-14 |
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| CN202111220267.8A Pending CN113801004A (zh) | 2016-05-13 | 2017-05-12 | 苯双酚衍生物及其制备方法和在医药上的应用 |
| CN201780020377.5A Active CN109415285B (zh) | 2016-05-13 | 2017-05-12 | 苯双酚衍生物及其制备方法和在医药上的应用 |
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| CN202111220267.8A Pending CN113801004A (zh) | 2016-05-13 | 2017-05-12 | 苯双酚衍生物及其制备方法和在医药上的应用 |
Country Status (2)
| Country | Link |
|---|---|
| CN (2) | CN113801004A (zh) |
| WO (1) | WO2017193986A1 (zh) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804043A (zh) * | 2010-04-30 | 2010-08-18 | 西安力邦制药有限公司 | 二联苯酚及其衍生物在治疗癫痫药物中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005063665A1 (en) * | 2003-12-23 | 2005-07-14 | Abraxis Bioscience, Inc | Propofol analogs, process for their preparation, and methods of use |
| CN105384607B (zh) * | 2014-08-22 | 2019-08-16 | 四川海思科制药有限公司 | 一种异丙基苯酚衍生物及其制备方法 |
-
2017
- 2017-05-12 CN CN202111220267.8A patent/CN113801004A/zh active Pending
- 2017-05-12 CN CN201780020377.5A patent/CN109415285B/zh active Active
- 2017-05-12 WO PCT/CN2017/084076 patent/WO2017193986A1/zh active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804043A (zh) * | 2010-04-30 | 2010-08-18 | 西安力邦制药有限公司 | 二联苯酚及其衍生物在治疗癫痫药物中的应用 |
Non-Patent Citations (1)
| Title |
|---|
| GANESH PANDEY等: "Mushroom Tyrosinase Catalysed Coupling of Hindered Phenols:A Novel Approach for the Synthesis of Diphenoquinones and Bisphenols", 《TETRAHEDRON LETTERS》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113801004A (zh) | 2021-12-17 |
| WO2017193986A1 (zh) | 2017-11-16 |
| CN109415285B (zh) | 2021-12-14 |
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Effective date of registration: 20231215 Address after: 856099 Xingfu Jiayuan Economic Development Zone, Gyerba, Nedong District, Shannan City, Tibet Autonomous Region Patentee after: Tibet Haisike Pharmaceutical Co.,Ltd. Address before: 611130 No.136 Baili Road, Chengdu cross strait science and Technology Industrial Development Park, Wenjiang District, Chengdu City, Sichuan Province Patentee before: SICHUAN HAISCO PHARMACEUTICAL Co.,Ltd. |