CN109394633A - Purple common perilla seed and its application in moisturizing or anti-oxidation efficacy cosmetics - Google Patents
Purple common perilla seed and its application in moisturizing or anti-oxidation efficacy cosmetics Download PDFInfo
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- CN109394633A CN109394633A CN201811608606.8A CN201811608606A CN109394633A CN 109394633 A CN109394633 A CN 109394633A CN 201811608606 A CN201811608606 A CN 201811608606A CN 109394633 A CN109394633 A CN 109394633A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/84—Products or compounds obtained by lyophilisation, freeze-drying
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Abstract
The present invention provides a kind of purple common perilla seed and its applications in moisturizing or anti-oxidation efficacy cosmetics.The purple common perilla seed, which is characterized in that preparation method includes: step 1: purple perilla seed is subjected to pulverization process with pulverizer；Step 2: the ethanol solution that mass percent is 50%~75% will be added in the purple perilla powder of seeds crushed in step 1, impregnate 12-36 hours；Step 3: by the resulting mixture control temperature of step 2 between 30 DEG C~50 DEG C, power 45-55W, frequency is 20~30min of ultrasound under the ultrasound condition of 35-45KHz；Step 4: by the mixture after the resulting ultrasound of step 3 under the conditions of 3000rpm~5000rpm, being centrifuged 20min~30min, take supernatant；Step 5: the resulting supernatant of step 4 being subjected to rotary evaporation in vacuo under conditions of vacuum degree is 0.094-0.096MPa, purple common perilla seed concentrate is obtained, is freeze-dried controlled at -53~-57 DEG C to get purple common perilla seed.It is applied to purple common perilla seed of the invention in cosmetics, has effects that skin moisture-keeping and oxidation resistant.
Description
Technical field
The invention belongs to personal-care supplies fields, are related to a Plant Extracts and its application, specifically a kind of
Purple common perilla seed and its application in skin moisture-keeping or anti-oxidation efficacy cosmetics.
Background technique
The seed of purple perilla seed, that is, purple perilla (Perilla frutescens (L.) Britt.), alias are called perillaseed, fragrant Soviet Union etc.,
Purple perilla is traditional one of the dual-purpose of drug and food class Chinese medicine in China, there is long plantation history in China, it is throughout the country everywhere.
It is expressly recited in Compendium of Material Medica, purple perilla has the effect of moistening lung to arrest cough, lower gas dissolving phlegm, wide intestines analgesic.Purple Perilla Seed Oil is as one
The vegetable oil of kind dual-purpose of drug and food, has many effects such as anti-aging, reducing blood lipid, anti-cancer, has great benefit to human body.
Have not yet to see its correlation as skin moisture-keeping or antioxidant be applied to skin apply some make up in research report.
Summary of the invention
The object of the present invention is to provide a kind of purple common perilla seed and its in moisturizing or anti-oxidation efficacy cosmetics
Using to expand application problem of the plant extracts as skin moisture-keeping or antioxidant in cosmetics.
In order to achieve the above object, the present invention provides a kind of purple common perilla seeds, which is characterized in that preparation method packet
It includes:
Step 1: purple perilla seed is subjected to pulverization process with pulverizer；
Step 2: by being added in the purple perilla powder of seeds crushed in step 1, the ethyl alcohol that mass percent is 50%~75% is molten
Liquid impregnates 12-36 hours；
Step 3: by step 2 resulting mixture control temperature between 30 DEG C~50 DEG C, power 45-55W, frequency is
Under the ultrasound condition of 35-45KHz, 20~30min of ultrasound；
Step 4: by the mixture after the resulting ultrasound of step 3 under the conditions of 3000rpm~5000rpm, centrifugation 20min~
30min takes supernatant；
Step 5: the resulting supernatant of step 4 is subjected to vacuum rotating under conditions of vacuum degree is 0.094-0.096MPa
Evaporation, obtains purple common perilla seed concentrate, is freeze-dried controlled at -53~-57 DEG C to get purple perilla seed extraction
Object.
The present invention also provides above-mentioned purple common perilla seeds to have the change of skin moisture-keeping or anti-oxidation efficacy in preparation
Application in cosmetic.
The present invention also provides a kind of cosmetics with skin moisture-keeping or anti-oxidation efficacy, which is characterized in that contain
Above-mentioned purple common perilla seed.
The present invention also provides a kind of face cream containing above-mentioned purple common perilla seed, which is characterized in that presses quality hundred
Divide than calculating, raw material composition and mass percentage are as follows:
The solid grease is the mixture of cetostearyl alcohol and lanolin, the i.e. quality of cetostearyl alcohol and lanolin
Than for 1:1.5-2.5；
The liquid fat is dimethicone (DC 200), isopropyl palmitate, caprylic/capric triglycerin acid, white
The mixture of oil, dimethicone (DC 200), isopropyl palmitate, caprylic/capric triglycerin acid and white oil mass ratio be
2:4.5-5.5:2.5-3.5:4.5-5.5；
The emulsifier is the mixture of Brij-721-72 and Brij-721-721, i.e., firmly
The mass ratio of lipidol polyoxyethylene ether-72 and Brij-721-721 is 9:10-12；
The assistant for emulsifying agent is mono fatty acid glyceride (monoglyceride)；
The rheology control agent is xanthan gum；
The moisturizer is the mixture of glycerol and 1,3-BDO, is calculated in mass ratio, i.e. glycerol: 1,3-BDO
Mixture be 3-5:3；
The preservative is the mixture that hydroxyphenyl methyl esters and hydroxyphenyl propyl ester form, hydroxyphenyl methyl esters and hydroxyphenyl third
The mass ratio of ester is 1.5-2.5:1；
The antioxidant is 2,6- di-tert-butyl p-cresol.
The present invention also provides a kind of face cream containing above-mentioned purple common perilla seed, which is characterized in that presses quality hundred
Divide than calculating, raw material composition and mass percentage are as follows:
The solid grease is the mixture of cetostearyl alcohol and lanolin, the i.e. quality of cetostearyl alcohol and lanolin
Than for 1:2；
The liquid fat be dimethicone (DC 200), isopropyl palmitate, caprylic/capric glycerinate,
The mixture of white oil, dimethicone (DC 200), isopropyl palmitate, caprylic/capric glycerinate and white oil quality
Than for 2:5:3:5；
The emulsifier is the mixture of Brij-721-72 and Brij-721-721, i.e., firmly
The mass ratio of lipidol polyoxyethylene ether-72 and Brij-721-721 is 9:11；
The assistant for emulsifying agent is mono fatty acid glyceride (monoglyceride)；
The rheology control agent is xanthan gum；
The moisturizer is the mixture of glycerol and 1,3-BDO, is calculated in mass ratio, i.e. glycerol: 1,3-BDO
Mixture be 4:3；
The preservative is the mixture that hydroxyphenyl methyl esters and hydroxyphenyl propyl ester form, hydroxyphenyl methyl esters and hydroxyphenyl third
The mass ratio of ester is 2:1；
The antioxidant is 2,6- di-tert-butyl p-cresol.
The present invention also provides a kind of preparation method containing the above-mentioned face cream containing above-mentioned purple common perilla seed,
It is characterised by comprising:
Step 1: purple common perilla seed, solid grease, liquid fat, emulsifier, assistant for emulsifying agent and antioxidant are formed
Oily heat phase to 75-90 DEG C of stirring and dissolving as A phase；
Step 2: rheology control agent, moisturizer being dissolved in deionized water and are heated to 75-90 DEG C of heat preservation as B phase；
Step 3: being 300rpm/min-550rpm/min in electric mixer revolving speed, bath temperature is 75-90 DEG C of condition
Under, the resulting B phase of step 2 is added in the resulting A phase of step 1 with the addition rate of 50-100mL/min, in electric stirring
Under the conditions of device is 75-90 DEG C with the revolving speed of 300rpm/min-550rpm/min, bath temperature, continue to stir 20min-30min；
Step 4: in homogenizer revolving speed being 10000rpm/min- by the resulting A phase of step 3 and B phase mixture
Homogeneous 1-3min under conditions of 20000rpm/min；
Step 5: the resulting mixture of step 4 being stirred under conditions of electric mixer revolving speed 80-120rpm/min, is added
When heat is to 45 DEG C -55 DEG C, preservative is added, continues to stir, be cooled to room temperature, discharging is to get to containing purple common perilla seed
Face cream.
The present invention also provides a kind of lotions containing above-mentioned purple common perilla seed, which is characterized in that presses quality percentage
Than calculating, the composition and mass percentage of raw material are as follows:
The solid grease is cetostearyl alcohol and stearic mixture, i.e. cetostearyl alcohol and stearic quality
Than for 2.5-3.5:1；
The liquid fat is the mixture of isopropyl palmitate, dimethicone and jojoba oil composition, palmitinic acid
The mass ratio of isopropyl ester, dimethicone and jojoba oil is 4.5-5.5:2.5-3.5:2；
The emulsifier is the mixture of the stearic alcohol ether of polyoxyethylene -2 and the stearic alcohol ether composition of polyoxyethylene -21, is gathered
The stearic alcohol ether of ethylene oxide -2, the stearic alcohol ether of polyoxyethylene -21 mass ratio be 1.2-1.8:2；
The moisturizer is Sodium Hyaluronate；
The rheology control agent is hydroxyethyl cellulose；
The preservative is the mixture that hydroxyphenyl methyl esters and hydroxyphenyl propyl ester form, hydroxyphenyl methyl esters and hydroxyphenyl third
The mass ratio of ester is 1.5-2.5:1；
The antioxidant is 2,6- di-tert-butyl hydroxy toluene.
The present invention also provides a kind of lotions containing above-mentioned purple common perilla seed, which is characterized in that presses quality percentage
Than calculating, the composition and mass percentage of raw material are as follows:
The solid grease is cetostearyl alcohol and stearic mixture, i.e. cetostearyl alcohol and stearic quality
Than for 3:1；
The liquid fat is the mixture of isopropyl palmitate, dimethicone and jojoba oil composition, palmitinic acid
The mass ratio of isopropyl ester, dimethicone and jojoba oil is 5:3:2；
The emulsifier is the mixture of the stearic alcohol ether of polyoxyethylene -2 and the stearic alcohol ether composition of polyoxyethylene -21, is gathered
The stearic alcohol ether of ethylene oxide -2, the stearic alcohol ether of polyoxyethylene -21 mass ratio be 1.5:2；
The moisturizer is Sodium Hyaluronate；
The rheology control agent is hydroxyethyl cellulose；
The preservative is the mixture that hydroxyphenyl methyl esters and hydroxyphenyl propyl ester form, hydroxyphenyl methyl esters and hydroxyphenyl third
The mass ratio of ester is 2:1；
The antioxidant is 2,6- di-tert-butyl hydroxy toluene.
The present invention also provides the preparation methods of the above-mentioned lotion containing purple common perilla seed, which is characterized in that including
Following steps:
Step 1: the oily heat phase that solid grease, liquid grease, emulsifier, antioxidant are formed to 65-90 DEG C of stirring
Dissolution is used as A phase；
Step 2: purple common perilla seed, rheology control agent and moisturizer being dissolved in deionized water and are heated to 65-90 DEG C
Heat preservation is used as B phase；
Step 3: under the conditions of controlling homogenizer revolving speed is 10000-20000rpm/min, by the resulting B phase of step 2
It is added in the resulting A phase of step 1 with the addition rate of 50-100mL/min, and continues homogeneous until A phase and B phase with homogenizer
It is uniformly mixed；
Step 4: by the A phase in step 3 and after B mixes uniformly, being naturally cooling to 75~80 DEG C, carry out mechanical defoaming；
It is that 100-500rpm/min is defoamed that the mechanical defoaming, which controls speed of agitator,；
Step 5: after the completion of step 4 defoaming when being naturally cooling to 40-50 DEG C, preservative is added, continues mechanical stirring to mixed
It closes uniformly and stops stirring after cooled to room temperature, speed of agitator 100-500rpm/min discharges to get purple perilla seed is contained
The lotion of extract.
Compared with prior art, the beneficial effects of the present invention are:
A kind of purple common perilla seed of the invention will be of the invention since it is with skin moisture-keeping and antioxidant effect
A kind of purple common perilla seed applied in skin applies some make up as a kind of skin moisture-keeping and antioxidant, play skin moisture-keeping and
Anti-oxidation efficacy.
Detailed description of the invention
Fig. 1 is purple common perilla seed and the Scavenging action to hydroxyl free radical figure of BHT；Abscissa is the addition of antioxidant sample solution
Amount.
Fig. 2 is that the MMV value containing purple common perilla seed and blank face cream changes with time figure；
Specific embodiment
Present invention will be further explained below with reference to specific examples.It should be understood that these embodiments are merely to illustrate the present invention
Rather than it limits the scope of the invention.In addition, it should also be understood that, after reading the content taught by the present invention, those skilled in the art
Member can make various changes or modifications the present invention, and such equivalent forms equally fall within the application the appended claims and limited
Range.
Embodiment 1
A kind of purple common perilla seed, specific steps are as follows:
(1) purple perilla seed is subjected to pulverization process with pulverizer；
(2) ethanol solution that mass percent is 70% will be added in the purple perilla powder of seeds crushed in step (1), impregnates
24 hours；
(3) by the resulting mixture control temperature of step (2) between 45 DEG C, power 50W, frequency is the super of 40KHz
Under the conditions of sound, ultrasonic 30min；
(4) mixture after the resulting ultrasound of step (3) is centrifuged 30min, takes supernatant under the conditions of 5000rpm；
(5) step (4) resulting supernatant is subjected to rotary evaporation in vacuo under conditions of vacuum degree is 0.095MPa, obtained
To purple common perilla seed concentrate, it is freeze-dried controlled at -55 DEG C to get purple common perilla seed.
Above-mentioned purple common perilla seed is subjected to experiment investigation to inoxidizability respectively, steps are as follows for specific experiment:
It is separately added into crystal violet solution that 0.3mL concentration is 0.1632mg/ml in 10mL cuvette and 1.2mL concentration is
The ferrous sulfate solution of 0.278mg/ml；The Potassium Hydrogen Phthalate buffer solution constant volume for being 4.01 with pH value places 30min
Afterwards, its absorbance A is surveyed at 590mm0；
It is separately added into crystal violet solution that 0.3mL concentration is 0.1632mg/ml in 10mL cuvette and 1.2mL concentration is
The ferrous sulfate solution of 0.278mg/ml；Add the hydrogenperoxide steam generator that 0.6mL concentration is 0.3mg/mL.It is 4.01 with pH value
Potassium Hydrogen Phthalate buffer solution constant volume, place 30min after, 590mm at survey its absorbance A b.
The measurement of apparent anti-hydroxy radical oxygenation efficiency:
It is separately added into crystal violet solution that 0.3mL concentration is 0.1632mg/ml in 10mL cuvette and 1.2mL concentration is
The ferrous sulfate solution of 0.278mg/ml；0.1,0.2,0.3,0.4,0.5ml sample solution is added；Add 0.6mL concentration
For the hydrogenperoxide steam generator of 0.3mg/mL, the Potassium Hydrogen Phthalate buffer solution constant volume for being 4.01 with pH value places 30min
Afterwards, its absorbance A s is measured.The sample solution is the BHT solution of 0.5% mass fraction or the purple perilla of 0.5% mass fraction
Seed extract solution.
Apparent anti-hydroxy radical oxygenation efficiency S calculation formula is as follows:
S (%)=(AS-Ab)/(A0-Ab)*100；
The system absorbance after a certain amount of antioxidant sample solution is added in As-；
Ab- does not add the system absorbance of antioxidant sample solution；
A0The system absorbance of hydrogenperoxide steam generator is not added.
It is different that antioxidant solution amount is added, Scavenging action to hydroxyl free radical is also different.(quality is dense with 0.5% for this experiment
Degree) BHT solution compares sample, under additional amount and 0.5% (mass concentration) purple common perilla seed amount of solution same case, compare it
Scavenging hydroxyl ability.Different additional amounts and Scavenging action to hydroxyl free radical change as shown in Figure 1, it will be seen from figure 1 that with
The rising of purple perilla seed effective component extracts content, inoxidizability be also gradually increased, and its increase trend it is also continuous
Enhancing.When purple perilla seed effective component is 0.4ml, inoxidizability also reaches maximum value.Simultaneously compared to the BHT of same concentrations
Solution, the antioxygenic property containing purple common perilla seed will be better than BHT solution, especially compare most both in 0.4ml
It is obvious.In conclusion purple common perilla seed has certain antioxidant effect.
Application Example 1
Using the resulting purple common perilla seed of embodiment 1 as skin moisture-keeping and antioxidant, answering in face cream is being prepared
With that is, a kind of face cream containing purple common perilla seed is calculated by mass percentage, and the content and composition of raw material are as follows:
The solid grease is the mixture of cetostearyl alcohol and lanolin, the i.e. quality of cetostearyl alcohol and lanolin
Than for 1:2；
The liquid fat be dimethicone (DC 200), isopropyl palmitate, caprylic/capric glycerinate,
The mixture of white oil, i.e. dimethicone (DC 200), isopropyl palmitate, caprylic/capric glycerinate and white oil matter
Amount is than being 2:5:3:5；
The emulsifier is the mixture of Brij-721-72 and Brij-721-721, i.e., firmly
The mass ratio of lipidol polyoxyethylene ether-72 and Brij-721-721 is 9:11；
The assistant for emulsifying agent is monoglyceride；
The rheology control agent is xanthan gum；
The moisturizer is the mixture of glycerol and 1,3-BDO, is calculated in mass ratio, i.e. glycerol: 1,3-BDO
Mixture be 4:3；
The preservative is the mixture that hydroxyphenyl methyl esters and hydroxyphenyl propyl ester form, hydroxyphenyl methyl esters and hydroxyphenyl third
The mass ratio of ester is 2:1；
The antioxidant is 2,6- di-tert-butyl p-cresol.
The above-mentioned face cream containing purple common perilla seed the preparation method comprises the following steps:
(1) oil for forming purple common perilla seed, solid grease, liquid fat, emulsifier, assistant for emulsifying agent and antioxidant
Heat phase is to 85 DEG C of stirring and dissolvings as A phase；
(2) rheology control agent, moisturizer are dissolved in deionized water and are heated to 85 DEG C of heat preservations as B phase；
It (3) is 500rpm/min in control electric mixer revolving speed, under the conditions of bath temperature is 85 DEG C, by step (2) institute
B phase control be added rate be 75mL/min, add it in the resulting A phase of step (1), with electric mixer with
Under the conditions of revolving speed, the bath temperature of 500rpm/min is 85 DEG C, continue to stir 30min；
(4) in the condition of homogenizer revolving speed 20000rpm/min after the resulting A phase of step (3) and B are mixed uniformly
Under, homogeneous 2min；
(5) the resulting mixture of step 4) stirs under conditions of electric mixer revolving speed 100rpm/min, is heated to 45
DEG C when, be added preservative, continue to stir, be cooled to room temperature, discharging to get arrive a kind of face cream containing purple common perilla seed.
Comparative example 1
Similar to Application Example 1, difference is, the face cream is calculated by mass percentage, the content of raw material
And composition is as follows:
Above-mentioned face cream the preparation method comprises the following steps:
(1) oily heat phase to 85 DEG C of stirring and dissolvings that solid grease, liquid fat, emulsifier and antioxidant form are made
For A phase；
(2) moisturizer is dissolved in deionized water and is heated to 85 DEG C of heat preservations as B phase；
It (3) is 500rpm/min in control electric mixer revolving speed, under the conditions of bath temperature is 85 DEG C, by step (2) institute
B phase control be added rate be 75mL/min, add it in the resulting A phase of step (1), with electric mixer with
Under the conditions of revolving speed, the bath temperature of 500rpm/min is 85 DEG C, continue to stir 30min；
(4) in the condition of homogenizer revolving speed 20000rpm/min after the resulting A phase of step (3) and B are mixed uniformly
Under, homogeneous 2min；
(5) the resulting mixture of step 4) stirs under conditions of electric mixer revolving speed 100rpm/min, is heated to 45
DEG C when, preservative is added, continues to stir, be cooled to room temperature, discharging is to get to the blank skin care for not adding purple common perilla seed
Frost.
Face cream and comparative example 1 by Application Example 1 containing purple common perilla seed do not contain the sky of purple common perilla seed
White face cream carries out experiment investigation to moisture retention, and using the method for humidity of skin measured value MMV, steps are as follows for specific experiment:
Before the experiments were performed, it needs to dry after cleaning volunteer's both hands arm skin, at 20 DEG C, air humidity exists
It is tested in 55% or so isoperibol, the scope of experiment of 42 × 2 (cm) is respectively chosen in experiment on both hands arm, so
The smearing of sample is carried out afterwards, and the unified right hand smears face cream of the Application Example 1 containing purple common perilla seed, and left hand smears comparison
Example 1 does not contain the blank face cream of purple common perilla seed.Before smearing, Test sites water content of stratum corneum is surveyed with popping one's head in
Amount, record data do blank sample.After smearing, every 30min, 60min, 90min, 120min is to the position water content again with probe
It measures, records data.
According to the increase of the MMV test number of ten volunteer right-hand man's arms, its average value is taken, show that right-hand man distinguishes
The MMV value added changed over time.Such as Fig. 2.
As seen from Figure 2, the MMV value added of face cream of the Application Example 1 containing purple common perilla seed is generally higher than
Comparative example 1 does not contain the blank face cream of purple common perilla seed, after smearing Application Example 1 containing purple common perilla seed
In 120min, the MMV value added of volunteer's arm skin is steadily and surely continuing to increase.It is very big to illustrate that product has moisture content of skin
It is promoted.
Application Example 2
The present invention also provides a kind of applications containing purple common perilla seed described in embodiment 1 in lotion, by quality
Percentage calculates, and the mass percentage and composition of raw material are as follows:
The solid grease is cetostearyl alcohol and stearic mixture, i.e. cetostearyl alcohol and stearic quality
Than for 3:1；
The liquid fat is the mixture of isopropyl palmitate, dimethicone and jojoba oil composition, palmitinic acid
The mass ratio of isopropyl ester, dimethicone and jojoba oil is 5:3:2；
The emulsifier is the mixture of the stearic alcohol ether of polyoxyethylene -2 and the stearic alcohol ether composition of polyoxyethylene -21, is gathered
The stearic alcohol ether of ethylene oxide -2, the stearic alcohol ether of polyoxyethylene -21 mass ratio be 1.5:2；
The moisturizer is Sodium Hyaluronate；
The rheology control agent is hydroxyethyl cellulose；
The preservative is the mixture that hydroxyphenyl methyl esters and hydroxyphenyl propyl ester form, hydroxyphenyl methyl esters and hydroxyphenyl third
The mass ratio of ester is 2:1；
The antioxidant is 2,6- di-tert-butyl hydroxy toluene.
The preparation method of the above-mentioned lotion containing purple common perilla seed, specific steps are as follows:
(1) stearic acid of 4g solid grease, that is, 3g cetostearyl alcohol and 1g, 10g liquid grease, that is, 5g palmitinic acid is different
The stearic alcohol ether of propyl ester, the jojoba oil of the dimethicone of 3g and 2g, 3.5g emulsifier, that is, 1.5g polyoxyethylene -2 and 2g's
The oily heat phase of the stearic alcohol ether of polyoxyethylene -21,0.05g antioxidant, that is, 2,6- di-tert-butyl hydroxy toluene composition is stirred to 85 DEG C
Mix dissolution as A phase keep the temperature it is spare；
(2) by the resulting purple common perilla seed of 0.15g embodiment 1,0.2g rheology control agent hydroxyethyl cellulose, 0.05g
Moisturizer Sodium Hyaluronate, which is dissolved in the deionized water of 81.75g and is heated to 85 DEG C of heat preservations, is used as B phase spare；
(3) under the conditions of controlling homogenizer revolving speed is 20000rpm/min, by the resulting B phase of step (2) with 75mL/
The addition rate of min is added in the resulting A phase of step (1), continues homogeneous 3min with homogenizer until A phase and B are mixed
It is even；
(4) after A phase and B are mixed uniformly, 75 DEG C are naturally cooling to, using blender control speed of agitator instead is 100rpm/
Min carries out mechanical defoaming；
(5) when being naturally cooling to 45 DEG C after the completion of step (4) defoaming, 0.3g preservative, that is, 0.2g hydroxyphenyl methyl esters is added
With the hydroxyphenyl propyl ester of 0.1g, continue to control agitator speed to be that 100rpm/min is stirred to being uniformly mixed, to naturally cold
But stop stirring after being cooled to room temperature, discharge to get a kind of lotion containing purple common perilla seed.
Above content is only the basic explanation under present inventive concept, and any etc. made by technical solution according to the present invention
Effect transformation, is within the scope of protection of the invention.
Claims (9)
1. a kind of purple common perilla seed, which is characterized in that preparation method includes:
Step 1: purple perilla seed is subjected to pulverization process with pulverizer；
Step 2: the ethanol solution that mass percent is 50%~75% will be added in the purple perilla powder of seeds crushed in step 1,
It impregnates 12-36 hours；
Step 3: by the resulting mixture control temperature of step 2 between 30 DEG C~50 DEG C, power 45-55W, frequency 35-
Under the ultrasound condition of 45KHz, 20~30min of ultrasound；
Step 4: by the mixture after the resulting ultrasound of step 3 under the conditions of 3000rpm~5000rpm, centrifugation 20min~
30min takes supernatant；
Step 5: the resulting supernatant of step 4 is subjected to vacuum rotating steaming under conditions of vacuum degree is 0.094-0.096MPa
Hair, obtains purple common perilla seed concentrate, is freeze-dried controlled at -53~-57 DEG C to get purple common perilla seed.
2. purple common perilla seed described in claim 1 is in the cosmetics that preparation has skin moisture-keeping or anti-oxidation efficacy
Using.
3. a kind of cosmetics with skin moisture-keeping or anti-oxidation efficacy, which is characterized in that contain purple described in claim 1
Perillaseed extract.
4. a kind of face cream containing purple common perilla seed described in claim 1, which is characterized in that by mass percentage
It calculates, raw material composition and mass percentage are as follows:
The solid grease is the mixture of cetostearyl alcohol and lanolin, i.e. the mass ratio of cetostearyl alcohol and lanolin is
1:1.5-2.5；
The liquid fat is the mixture of dimethicone, isopropyl palmitate, caprylic/capric glycerinate, white oil,
Dimethicone, isopropyl palmitate, caprylic/capric glycerinate and white oil mass ratio be 2:4.5-5.5:2.5-3.5:
4.5-5.5；
The emulsifier is the mixture of Brij-721-72 and Brij-721-721, i.e. stearyl alcohol
The mass ratio of polyoxyethylene ether-72 and Brij-721-721 is 9:10-12；
The assistant for emulsifying agent is mono fatty acid glyceride；
The rheology control agent is xanthan gum；
The moisturizer is the mixture of glycerol and 1,3-BDO, is calculated in mass ratio, i.e. glycerol: 1,3-BDO mixes
Conjunction object is 3-5:3；
The mixture that the preservative forms for hydroxyphenyl methyl esters and hydroxyphenyl propyl ester, hydroxyphenyl methyl esters and hydroxyphenyl propyl ester
Mass ratio is 1.5-2.5:1；
The antioxidant is 2,6- di-tert-butyl p-cresol.
5. a kind of face cream containing purple common perilla seed described in claim 1, which is characterized in that by mass percentage
It calculates, raw material composition and mass percentage are as follows:
The solid grease is the mixture of cetostearyl alcohol and lanolin, i.e. the mass ratio of cetostearyl alcohol and lanolin is
1:2；
The liquid fat is the mixture of dimethicone, isopropyl palmitate, caprylic/capric glycerinate, white oil,
Dimethicone, isopropyl palmitate, caprylic/capric glycerinate and white oil mass ratio be 2:5:3:5；
The emulsifier is the mixture of Brij-721-72 and Brij-721-721, i.e. stearyl alcohol
The mass ratio of polyoxyethylene ether-72 and Brij-721-721 is 9:11；
The assistant for emulsifying agent is mono fatty acid glyceride；
The rheology control agent is xanthan gum；
The moisturizer is the mixture of glycerol and 1,3-BDO, is calculated in mass ratio, i.e. glycerol: 1,3-BDO mixes
Conjunction object is 4:3；
The mixture that the preservative forms for hydroxyphenyl methyl esters and hydroxyphenyl propyl ester, hydroxyphenyl methyl esters and hydroxyphenyl propyl ester
Mass ratio is 2:1；
The antioxidant is 2,6- di-tert-butyl p-cresol.
6. the preparation method of the face cream of purple common perilla seed described in claim 4 or 5 characterized by comprising
Step 1: the oil that purple common perilla seed, solid grease, liquid fat, emulsifier, assistant for emulsifying agent and antioxidant are formed
Heat phase is to 75-90 DEG C of stirring and dissolving as A phase；
Step 2: rheology control agent, moisturizer being dissolved in deionized water and are heated to 75-90 DEG C of heat preservation as B phase；
Step 3: it is 300rpm/min-550rpm/min in electric mixer revolving speed, it, will under the conditions of bath temperature is 75-90 DEG C
The resulting B phase of step 2 is added in the resulting A phase of step 1 with the addition rate of 50-100mL/min, electric mixer with
Under the conditions of revolving speed, the bath temperature of 300rpm/min-550rpm/min is 75-90 DEG C, continue to stir 20min-30min；
Step 4: in homogenizer revolving speed being 10000rpm/min-20000rpm/ by the resulting A phase of step 3 and B phase mixture
Homogeneous 1-3min under conditions of min；
Step 5: the resulting mixture of step 4 being stirred under conditions of electric mixer revolving speed 80-120rpm/min, is heated to
At 45 DEG C -55 DEG C, preservative is added, continues to stir, be cooled to room temperature, discharges to get the skin care containing purple common perilla seed is arrived
Frost.
7. a kind of lotion containing purple common perilla seed described in claim 1, which is characterized in that it is calculated by mass percentage,
The composition and mass percentage of its raw material are as follows:
The solid grease is cetostearyl alcohol and stearic mixture, i.e. cetostearyl alcohol and stearic mass ratio is
2.5-3.5:1；
The liquid fat is the mixture of isopropyl palmitate, dimethicone and jojoba oil composition, palmitinic acid isopropyl
The mass ratio of ester, dimethicone and jojoba oil is 4.5-5.5:2.5-3.5:2；
The emulsifier is the mixture of the stearic alcohol ether of polyoxyethylene -2 and the stearic alcohol ether composition of polyoxyethylene -21, polyoxy second
The stearic alcohol ether of alkene -2, the stearic alcohol ether of polyoxyethylene -21 mass ratio be 1.2-1.8:2；
The moisturizer is Sodium Hyaluronate；
The rheology control agent is hydroxyethyl cellulose；
The mixture that the preservative forms for hydroxyphenyl methyl esters and hydroxyphenyl propyl ester, hydroxyphenyl methyl esters and hydroxyphenyl propyl ester
Mass ratio is 1.5-2.5:1；
The antioxidant is 2,6- di-tert-butyl hydroxy toluene.
8. a kind of lotion containing purple common perilla seed described in claim 1, which is characterized in that it is calculated by mass percentage,
The composition and mass percentage of its raw material are as follows:
The solid grease is cetostearyl alcohol and stearic mixture, i.e. cetostearyl alcohol and stearic mass ratio is
3:1；
The liquid fat is the mixture of isopropyl palmitate, dimethicone and jojoba oil composition, palmitinic acid isopropyl
The mass ratio of ester, dimethicone and jojoba oil is 5:3:2；
The emulsifier is the mixture of the stearic alcohol ether of polyoxyethylene -2 and the stearic alcohol ether composition of polyoxyethylene -21, polyoxy second
The stearic alcohol ether of alkene -2, the stearic alcohol ether of polyoxyethylene -21 mass ratio be 1.5:2；
The moisturizer is Sodium Hyaluronate；
The rheology control agent is hydroxyethyl cellulose；
The mixture that the preservative forms for hydroxyphenyl methyl esters and hydroxyphenyl propyl ester, hydroxyphenyl methyl esters and hydroxyphenyl propyl ester
Mass ratio is 2:1；
The antioxidant is 2,6- di-tert-butyl hydroxy toluene.
9. the preparation method of the lotion described in claim 7 or 8 containing purple common perilla seed, which is characterized in that including as follows
Step:
Step 1: the oily heat phase that solid grease, liquid grease, emulsifier, antioxidant are formed to 65-90 DEG C of stirring and dissolving
As A phase；
Step 2: purple common perilla seed, rheology control agent and moisturizer being dissolved in deionized water and are heated to 65-90 DEG C of heat preservation
As B phase；
Step 3: control homogenizer revolving speed be 10000-20000rpm/min under the conditions of, by the resulting B phase of step 2 with
The addition rate of 50-100mL/min is added in the resulting A phase of step 1, and continues homogeneous until A phase is mixed with B phase with homogenizer
It closes uniform；
Step 4: by the A phase in step 3 and after B mixes uniformly, being naturally cooling to 75~80 DEG C, carry out mechanical defoaming；It is described
Mechanical defoaming i.e. control speed of agitator be 100-500rpm/min defoamed；
Step 5: when being naturally cooling to 40-50 DEG C after the completion of step 4 defoaming, preservative is added, it is equal to mixing to continue mechanical stirring
Stop stirring, speed of agitator 100-500rpm/min after even and cooled to room temperature, discharging is extracted to get containing purple perilla seed
The lotion of object.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811608606.8A CN109394633A (en) | 2018-12-27 | 2018-12-27 | Purple common perilla seed and its application in moisturizing or anti-oxidation efficacy cosmetics |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811608606.8A CN109394633A (en) | 2018-12-27 | 2018-12-27 | Purple common perilla seed and its application in moisturizing or anti-oxidation efficacy cosmetics |
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| CN116999484A (en) * | 2023-10-07 | 2023-11-07 | 云南英格生物技术有限公司 | Application of perilla seed oil meal extract in preparation of 5 alpha-reductase inhibitor |
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