CN109374889B - 标记的hsp90抑制剂的用途 - Google Patents

标记的hsp90抑制剂的用途 Download PDF

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CN109374889B
CN109374889B CN201810715481.2A CN201810715481A CN109374889B CN 109374889 B CN109374889 B CN 109374889B CN 201810715481 A CN201810715481 A CN 201810715481A CN 109374889 B CN109374889 B CN 109374889B
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tumor
hsp90
cells
patient
hsp90 inhibitor
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CN109374889A (zh
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加布里拉·奇奥斯
那加瓦拉基肖尔·佩拉塞提
詹森·S·路易斯
史蒂文·M·拉尔森
托尼·塔尔多内
玛丽·L·阿尔波
艾瑞卡·M·戈梅斯-达伽马
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Memorial Sloan Kettering Cancer Center
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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CN201810715481.2A 2011-07-08 2012-07-06 标记的hsp90抑制剂的用途 Expired - Fee Related CN109374889B (zh)

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Application Number Priority Date Filing Date Title
US201161506010P 2011-07-08 2011-07-08
US61/506,010 2011-07-08
CN201280040632.XA CN104081203B (zh) 2011-07-08 2012-07-06 标记的hsp90抑制剂的用途
PCT/US2012/045861 WO2013009655A2 (en) 2011-07-08 2012-07-06 Uses of labeled hsp90 inhibitors

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CN109374889B true CN109374889B (zh) 2022-04-19

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CN201280040606.7A Expired - Fee Related CN104081206B (zh) 2011-07-08 2012-07-06 标记的hsp90抑制剂的用途
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US (4) US9555137B2 (enExample)
EP (3) EP3709022A1 (enExample)
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CN (3) CN109374889B (enExample)
AU (3) AU2012282903A1 (enExample)
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CA (2) CA2841069C (enExample)
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