CN109315396A - A kind of preparation method of strong glutaral solution - Google Patents
A kind of preparation method of strong glutaral solution Download PDFInfo
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- CN109315396A CN109315396A CN201710635028.6A CN201710635028A CN109315396A CN 109315396 A CN109315396 A CN 109315396A CN 201710635028 A CN201710635028 A CN 201710635028A CN 109315396 A CN109315396 A CN 109315396A
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- Prior art keywords
- stirring
- agitation tank
- dense
- strong
- glutaraldehyde
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/34—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-halogen bonds; Phosphonium salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pest Control & Pesticides (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of preparation method of strong glutaral solution, which belongs to disinfectant for animals field；Its composition of raw materials includes: that the raw material of the invention used includes: dense glutaraldehyde 21-23%, quaternary alkylphosphonium salt 6-8%, medicinal hardening agent 1%, deionized water 70% by weight ratio count by weight percentage；Its technique is: the deionized water of formula ratio being sent into Agitation Tank, is heated to 45 DEG C -50 DEG C, the dense glutaraldehyde of formula ratio is added after Agitation Tank while stirring after continuing stirring 0.3-0.4 hours and stops stirring；It is cooled to room temperature, the quaternary alkylphosphonium salt of formula ratio, medicinal hardening agent are sequentially added into Agitation Tank, stirring is got product after 0.1-0.2 hours；The advantages of production method, is: using common apparatus, simple process, good quality of product；Product can arbitrarily be mixed with water or ethyl alcohol, be a kind of outstanding Cidex-7, be can be used for the disinfection of animal house, animal body surface, have good killing effect to bacterium, virus and fungi, mycoplasma.
Description
Technical field
The invention belongs to disinfectant for animals field more particularly to a kind of preparation methods of strong glutaral solution.
Background technique
Strong glutaral solution be a kind of wide spectrum, it is efficient, quick-acting, less toxic, to person poultry harmless, non-stimulated disinfectant, dense penta
Dialdehyde solution sterilizing mechanisms are by aldehyde radical, and such drug mainly acts on thin base, hydroxyl, carboxyl and the amino of mycoprotein,
It can be allowed to be alkylated, protein coagulating is caused to cause bacterial death, the infection of the upper respiratory tract is not easy to cause in band body disinfection, to gold
Category corrosivity is small, and Disinfection Effect is not by such environmental effects such as the hardness of water, organic matter, temperature.Strong glutaral solution infiltration
Property it is strong, stability is good, pH value be 7.5-8.5 when, bactericidal effect is most strong, when pH value be greater than 9 when almost lose sterilizing ability, it is right
Various viruses, bacterial propagule, gemma, virus, tubercle bacillus, mycoplasma, fungi, helminth etc. have powerful effect, can be fast
Speed kill all microorganisms, major advantage is: 1. wide spectrums, efficiently；2. low using concentration, irritation is small, corrosivity is low；3. receiving
The influence of machine object is small, and 20% organic matter influences bactericidal effect little；The disadvantage is that sterilization time is long, sterilizing will generally reach 10
A hour.For strong glutaral solution since the bactericidal effect time is long, using effect is good, is known as after formaldehyde and ethylene oxide disinfectant
Product best in chemical disinfection bactericidal agent later.Traditional dense glutaraldehyde is using quaternary ammonium salt as auxiliary material, with science and technology
It is constantly progressive, it has been found that the using effect of quaternary alkylphosphonium salt is greatly better than quaternary ammonium salt, and the present invention is with dense glutaraldehyde, quaternary alkylphosphonium salt, medicine
It is raw material with hardening agent, deionized water, finished product is made by processes such as the blending dissolutions of raw material.This method it is main excellent
Point is: using common apparatus, simple process, good quality of product, discharge without toxic and harmful gas and liquid, product can with water or
Ethyl alcohol arbitrarily mixes, and is a kind of outstanding Cidex-7, can be used for the disinfection of animal house, animal body surface.
Summary of the invention
Present invention mainly solves the problem of be to provide the preparation method of strong glutaral solution a kind of, the raw material that the present invention uses
It by weight ratio include: dense glutaraldehyde 21-23%, quaternary alkylphosphonium salt 6-8%, medicinal hardening agent 1%, deionized water 70%.
The present invention can be achieved through the following technical solutions:
(1) deionized water of formula ratio is sent into Agitation Tank, 45 DEG C -50 DEG C is heated to, while stirring by the dense of formula ratio
Glutaraldehyde continues to stop stirring after stirring 0.3-0.4 hours after Agitation Tank is added.
(2) it is cooled to room temperature, the quaternary alkylphosphonium salt of formula ratio, medicinal hardening agent are sequentially added into Agitation Tank, stirring 0.1-0.2 is small
When after get product.
(3) application method of strong glutaral solution is: for the disinfection of animal house, animal body surface, usage amount is to dynamic
The disinfection of object mew is spraying with 500 times of liquid, sterilizes to livestock and poultry body surface spraying with 2000 times of liquid.
Preferably, the purity of the dense glutaraldehyde is 80%.
The beneficial effects of the present invention are: provide a kind of preparation method of strong glutaral solution, the advantages of the production method
It is: using common apparatus, simple process, good quality of product；Product can arbitrarily be mixed with water or ethyl alcohol, and being that one kind is outstanding disappears
Malicious antiseptic can be used for the disinfection of animal house, animal body surface, have good killing to bacterium, virus and fungi, mycoplasma
Effect.
Specific embodiment
Embodiment 1
The deionized water that total amount is 70% will be accounted for and be sent into Agitation Tank, be heated to 45 DEG C, will account for total amount while stirring is 21%
Dense glutaraldehyde continues to stop stirring after stirring 0.3 hour after Agitation Tank is added；It is cooled to room temperature, quaternary phosphonium of the total amount for 8% will be accounted for
Salt accounts for the medicinal hardening agent that total amount is 1% and sequentially adds Agitation Tank, and stirring is got product after 0.1 hour.
Embodiment 2
The deionized water that total amount is 70% will be accounted for and be sent into Agitation Tank, be heated to 47.5 DEG C, will account for total amount while stirring is 22%
Dense glutaraldehyde be added Agitation Tank after continue stirring 0.35 hour after stop stirring；It is cooled to room temperature, season of the total amount for 7% will be accounted for
Microcosmic salt accounts for the medicinal hardening agent that total amount is 1% and sequentially adds Agitation Tank, and stirring is got product after 0.15 hour.
Embodiment 3
The deionized water that total amount is 70% will be accounted for and be sent into Agitation Tank, be heated to 50 DEG C, will account for total amount while stirring is 23%
Dense glutaraldehyde continues to stop stirring after stirring 0.4 hour after Agitation Tank is added；It is cooled to room temperature, quaternary phosphonium of the total amount for 6% will be accounted for
Salt accounts for the medicinal hardening agent that total amount is 1% and sequentially adds Agitation Tank, and stirring is got product after 0.2 hour.
Claims (3)
1. a kind of preparation method of strong glutaral solution, composition of raw materials includes: that the present invention uses count by weight percentage
Raw material includes: dense glutaraldehyde 21-23%, quaternary alkylphosphonium salt 6-8%, medicinal hardening agent 1%, deionized water 70% by weight ratio；Its feature
It is:
(1) deionized water of formula ratio is sent into Agitation Tank, 45 DEG C -50 DEG C is heated to, while stirring by the dense of formula ratio
Glutaraldehyde continues to stop stirring after stirring 0.3-0.4 hours after Agitation Tank is added；
(2) it is cooled to room temperature, the quaternary alkylphosphonium salt of formula ratio, medicinal hardening agent are sequentially added into Agitation Tank, after stirring 0.1-0.2 hours
It gets product.
2. a kind of production method of strong glutaral solution according to claim 1, it is characterized in that: the dense glutaraldehyde
Purity is 80%.
3. the application method of strong glutaral solution is: for the disinfection of animal house, animal body surface, usage amount is to animal house
Disinfection is spraying with 500 times of liquid, sterilizes to livestock and poultry body surface spraying with 2000 times of liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710635028.6A CN109315396A (en) | 2017-07-30 | 2017-07-30 | A kind of preparation method of strong glutaral solution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710635028.6A CN109315396A (en) | 2017-07-30 | 2017-07-30 | A kind of preparation method of strong glutaral solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109315396A true CN109315396A (en) | 2019-02-12 |
Family
ID=65245358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710635028.6A Pending CN109315396A (en) | 2017-07-30 | 2017-07-30 | A kind of preparation method of strong glutaral solution |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109315396A (en) |
-
2017
- 2017-07-30 CN CN201710635028.6A patent/CN109315396A/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190212 |
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| WD01 | Invention patent application deemed withdrawn after publication |