CN109288963A - 一种药物组合物、滋阴益肾汤及其制备方法 - Google Patents

一种药物组合物、滋阴益肾汤及其制备方法 Download PDF

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CN109288963A
CN109288963A CN201811482119.1A CN201811482119A CN109288963A CN 109288963 A CN109288963 A CN 109288963A CN 201811482119 A CN201811482119 A CN 201811482119A CN 109288963 A CN109288963 A CN 109288963A
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冯立军
叶长明
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Lingshen Biotechnology (dalian) Co Ltd
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Abstract

本发明公开了一种药物组合物、滋阴益肾汤及其制备方法，所述药物组合物包括如下重量份的组分：人参3～8份、茯苓5～15份、黄精5～10份、山药10～20份、枸杞5～15份、陈皮3～8份、芡实5～15份、覆盆子3～8份、阿胶3～8份、肉桂1～3份、白果5～15份、白芷3～8份、莲子5～10份。本发明所述的药物组合物及滋阴益肾汤用于肾阴亏损、头晕耳鸣、腰膝酸软、骨蒸潮热、盗汗、消渴，滋阴补肾、养心安神、益肾固精缩尿、养肝明目，采用药食同源的原料，无副作用。

Description

一种药物组合物、滋阴益肾汤及其制备方法
技术领域
本发明涉及一种药物组合物及该药物组合物制成的汤剂，具体涉及一种药物组合物、滋阴益肾汤及其制备方法。
背景技术
肾阴虚是肾虚的一种类型，为中医名词术语，指肾脏阴液不足之证，又称肾水不足或真阴不足。是由于肾阴亏损，失于滋养，虚热内生所表现的证候，中医临床称为肾阴虚证。多由久病耗伤，或禀赋不足，或房劳过度，或过服温燥劫阴之品所致。肾阴以肾中精气为物质基础，对各脏腑组织起着滋养和濡润的作用，与肾阳相互为用，共为人体生命活动之本。若肾阴不足，则津液分泌减少，表现为阴虚内热及阴虚阳亢之象，证见腰膝酸痛，头晕耳鸣，失眠多梦，五心烦热，潮热盗汗，咽干颧红，舌红少津无苔，脉细数等。
发明内容
本发明针对以上问题的提出，而研究设计一种药物组合物、滋阴益肾汤及其制备方法。本发明采用的技术手段如下：
一种药物组合物，包括如下重量份的组分：人参3～8份、茯苓5～15份、黄精5～10份、山药10～20份、枸杞5～15份、陈皮3～8份、芡实5～15份、覆盆子3～8份、阿胶3～8份、肉桂1～3份、白果5～15份、白芷3～8份、莲子5～10份。
进一步地，所述药物组合物包括如下重量份的组分：人参4～7份、茯苓8～12份、黄精7～9份、山药13～17份、枸杞8～12份、陈皮4～6份、芡实8～12份、覆盆子4～6份、阿胶4～6份、肉桂1～2份、白果8～12份、白芷4～6份、莲子7～9份。
进一步地，所述药物组合物包括如下重量份的组分：人参6份、茯苓10份、黄精8份、山药15份、枸杞10份、陈皮5份、芡实10份、覆盆子5份、阿胶5份、肉桂2份、白果10份、白芷5份、莲子8份。
进一步地，所述药物组合物还包括蜂蜜。
一种滋阴益肾汤，为本发明所述的任意一种药物组合的水煎提取物。
一种本发明所述的滋阴益肾汤的制备方法，为水煎提取法，包括以下步骤：
a.一次提取：将药物组合物和水以重量比为1：(10～15)的比例混合提取，提取时间为1～3小时；
b.二次提取：将步骤a剩余的药渣与药物组合物原始重量10～15倍的水混合提取，提取时间为1～3小时；
c.三次提取：将步骤b剩余的药渣与药物组合物原始重量10～15倍的水混合提取，提取时间为1～3小时。
进一步地，步骤a中水的重量为药物组合物重量的13倍，步骤b中水的重量为药物组合物原始重量的12倍，步骤c中水的重量为药物组合物原始重量的12倍，水煎的压力条件为在一个大气压基础上加压1.5kPa～2kPa。
进一步地，还包括灌装和杀菌步骤。
与现有技术比较，本发明所述的药物组合物及滋阴益肾汤用于肾阴亏损、头晕耳鸣、腰膝酸软、骨蒸潮热、盗汗、消渴，滋阴补肾、养心安神、益肾固精缩尿、养肝明目，采用药食同源的原料，无副作用。
具体实施方式
本发明的所述的药物组合物的实施例如下表所示，单位：克。
上述实施例中，蜂蜜的量酌量添加即可。
一种滋阴益肾汤的制备方法，包括以下步骤：
a.一次提取：将药物组合物和水以重量比为1：(10～15)的比例混合提取，优选药物组合物和水以重量比为1:13，提取时间为1～3小时，优选1小时；
b.二次提取：将步骤a剩余的药渣与药物组合物原始重量10～15倍的水混合提取，优选水的重量为药物组合物原始重量的12倍，提取时间为1～3小时，优选1小时；
c.三次提取：将步骤b剩余的药渣与药物组合物原始重量10～15倍的水混合提取，优选水的重量为药物组合物原始重量的12倍，提取时间为1～3小时，优选1小时。
本实施例中，水煎的压力条件为在一个大气压基础上加压1.5kPa～2kPa。所述元气恢复汤的制备方法还包括灌装和杀菌步骤，还包括急冻锁鲜工序，所述急冻锁鲜为将提取物在-35℃以下进行冷冻，实现快速冷冻的效果，本实施例优选冷冻温度为-40℃～-35℃。
经50名不同年龄的人试验，本实施例未发现任何毒副作用，对肾阴亏损、头晕耳鸣、腰膝酸软、骨蒸潮热、盗汗、消渴等症状有明显的治疗效果，所有服用的患者的症状均明显缓解或消失。
以上所述的实施例仅仅是对本发明的优选实施方式进行描述，并非对本发明的范围进行限定，在不脱离本发明设计精神的前提下，本领域普通技术人员对本发明的技术方案做出的各种变形和改进，均应落入本发明权利要求书确定的保护范围内。

Claims (8)

1.一种药物组合物，包括如下重量份的组分：人参3～8份、茯苓5～15份、黄精5～10份、山药10～20份、枸杞5～15份、陈皮3～8份、芡实5～15份、覆盆子3～8份、阿胶3～8份、肉桂1～3份、白果5～15份、白芷3～8份、莲子5～10份。
2.根据权利要求1所述的药物组合物，其特征在于：包括如下重量份的组分：人参4～7份、茯苓8～12份、黄精7～9份、山药13～17份、枸杞8～12份、陈皮4～6份、芡实8～12份、覆盆子4～6份、阿胶4～6份、肉桂1～2份、白果8～12份、白芷4～6份、莲子7～9份。
3.根据权利要求2所述的药物组合物，其特征在于：包括如下重量份的组分：人参6份、茯苓10份、黄精8份、山药15份、枸杞10份、陈皮5份、芡实10份、覆盆子5份、阿胶5份、肉桂2份、白果10份、白芷5份、莲子8份。
4.根据权利要求1至3中任意一项所述的药物组合物，其特征在于：还包括蜂蜜。
5.一种滋阴益肾汤，为权利要求1至4中所述的任意一种药物组合的水煎提取物。
6.一种权利要求5所述的滋阴益肾汤的制备方法，为水煎提取法，包括以下步骤：
a.一次提取：将药物组合物和水以重量比为1：(10～15)的比例混合提取，提取时间为1～3小时；
b.二次提取：将步骤a剩余的药渣与药物组合物原始重量10～15倍的水混合提取，提取时间为1～3小时；
c.三次提取：将步骤b剩余的药渣与药物组合物原始重量10～15倍的水混合提取，提取时间为1～3小时。
7.根据权利要求6所述的滋阴益肾汤的制备方法，其特征在于：步骤a中水的重量为药物组合物重量的13倍，步骤b中水的重量为药物组合物原始重量的12倍，步骤c中水的重量为药物组合物原始重量的12倍，水煎的压力条件为在一个大气压基础上加压1.5kPa～2kPa。
8.根据权利要求7所述的滋阴益肾汤的制备方法，其特征在于：还包括灌装和杀菌步骤。
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