CN109288696A - Mixture is used in flank of tooth cleaning - Google Patents
Mixture is used in flank of tooth cleaning Download PDFInfo
- Publication number
- CN109288696A CN109288696A CN201810812006.7A CN201810812006A CN109288696A CN 109288696 A CN109288696 A CN 109288696A CN 201810812006 A CN201810812006 A CN 201810812006A CN 109288696 A CN109288696 A CN 109288696A
- Authority
- CN
- China
- Prior art keywords
- flank
- tooth
- mass
- tooth cleaning
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 46
- 238000004140 cleaning Methods 0.000 title abstract description 52
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 22
- 239000002245 particle Substances 0.000 claims abstract description 14
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 11
- 239000000470 constituent Substances 0.000 claims abstract description 11
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 3
- 239000011575 calcium Substances 0.000 claims description 3
- 229910052791 calcium Inorganic materials 0.000 claims description 3
- 238000003682 fluorination reaction Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 229940091249 fluoride supplement Drugs 0.000 description 9
- 230000009545 invasion Effects 0.000 description 8
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 8
- -1 Karaya Gum Polymers 0.000 description 7
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 239000001768 carboxy methyl cellulose Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000003755 preservative agent Substances 0.000 description 6
- 239000006071 cream Substances 0.000 description 5
- 239000011230 binding agent Substances 0.000 description 4
- 150000001720 carbohydrates Chemical class 0.000 description 4
- 235000014633 carbohydrates Nutrition 0.000 description 4
- 150000002222 fluorine compounds Chemical class 0.000 description 4
- 229920000591 gum Polymers 0.000 description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 4
- 210000000214 mouth Anatomy 0.000 description 4
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 description 4
- 230000002335 preservative effect Effects 0.000 description 4
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 4
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 description 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 3
- 235000010443 alginic acid Nutrition 0.000 description 3
- 229920000615 alginic acid Polymers 0.000 description 3
- 239000000783 alginic acid Substances 0.000 description 3
- 229960001126 alginic acid Drugs 0.000 description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 210000003298 dental enamel Anatomy 0.000 description 3
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 3
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 3
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 3
- 229960004711 sodium monofluorophosphate Drugs 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 229940032147 starch Drugs 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 2
- RLLPVAHGXHCWKJ-IEBWSBKVSA-N (3-phenoxyphenyl)methyl (1s,3s)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(Cl)Cl)[C@@H]1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-IEBWSBKVSA-N 0.000 description 2
- BTMZHHCFEOXAAN-UHFFFAOYSA-N 2-[bis(2-hydroxyethyl)amino]ethanol;2-dodecylbenzenesulfonic acid Chemical compound OCCN(CCO)CCO.CCCCCCCCCCCCC1=CC=CC=C1S(O)(=O)=O BTMZHHCFEOXAAN-UHFFFAOYSA-N 0.000 description 2
- DDFHBQSCUXNBSA-UHFFFAOYSA-N 5-(5-carboxythiophen-2-yl)thiophene-2-carboxylic acid Chemical compound S1C(C(=O)O)=CC=C1C1=CC=C(C(O)=O)S1 DDFHBQSCUXNBSA-UHFFFAOYSA-N 0.000 description 2
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 2
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical group OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 108010011485 Aspartame Proteins 0.000 description 2
- 229920001661 Chitosan Polymers 0.000 description 2
- 229920001287 Chondroitin sulfate Polymers 0.000 description 2
- 239000001879 Curdlan Substances 0.000 description 2
- 229920002558 Curdlan Polymers 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- 229920002148 Gellan gum Polymers 0.000 description 2
- 229920002907 Guar gum Polymers 0.000 description 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- 229930195725 Mannitol Natural products 0.000 description 2
- 244000046052 Phaseolus vulgaris Species 0.000 description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 229920002253 Tannate Polymers 0.000 description 2
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 2
- 235000010489 acacia gum Nutrition 0.000 description 2
- 235000010358 acesulfame potassium Nutrition 0.000 description 2
- 229960004998 acesulfame potassium Drugs 0.000 description 2
- 239000000619 acesulfame-K Substances 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 150000004781 alginic acids Chemical class 0.000 description 2
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 2
- BTBJBAZGXNKLQC-UHFFFAOYSA-N ammonium lauryl sulfate Chemical compound [NH4+].CCCCCCCCCCCCOS([O-])(=O)=O BTBJBAZGXNKLQC-UHFFFAOYSA-N 0.000 description 2
- 239000000605 aspartame Substances 0.000 description 2
- 235000010357 aspartame Nutrition 0.000 description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 2
- 229960003438 aspartame Drugs 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 description 2
- 229910001634 calcium fluoride Inorganic materials 0.000 description 2
- 229940096529 carboxypolymethylene Drugs 0.000 description 2
- 235000010418 carrageenan Nutrition 0.000 description 2
- 239000000679 carrageenan Substances 0.000 description 2
- 229920001525 carrageenan Polymers 0.000 description 2
- 229940113118 carrageenan Drugs 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 235000010980 cellulose Nutrition 0.000 description 2
- 229940059329 chondroitin sulfate Drugs 0.000 description 2
- 235000019316 curdlan Nutrition 0.000 description 2
- 229940078035 curdlan Drugs 0.000 description 2
- 208000002925 dental caries Diseases 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 2
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 235000010492 gellan gum Nutrition 0.000 description 2
- 239000000216 gellan gum Substances 0.000 description 2
- 235000010417 guar gum Nutrition 0.000 description 2
- 239000000665 guar gum Substances 0.000 description 2
- 229960002154 guar gum Drugs 0.000 description 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 2
- 239000000832 lactitol Substances 0.000 description 2
- 235000010448 lactitol Nutrition 0.000 description 2
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 description 2
- 229960003451 lactitol Drugs 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 229940094506 lauryl betaine Drugs 0.000 description 2
- 235000010449 maltitol Nutrition 0.000 description 2
- 239000000845 maltitol Substances 0.000 description 2
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 2
- 229940035436 maltitol Drugs 0.000 description 2
- 239000000594 mannitol Substances 0.000 description 2
- 235000010355 mannitol Nutrition 0.000 description 2
- 229960001855 mannitol Drugs 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229920000609 methyl cellulose Polymers 0.000 description 2
- 235000010981 methylcellulose Nutrition 0.000 description 2
- 239000001923 methylcellulose Substances 0.000 description 2
- DVEKCXOJTLDBFE-UHFFFAOYSA-N n-dodecyl-n,n-dimethylglycinate Chemical compound CCCCCCCCCCCC[N+](C)(C)CC([O-])=O DVEKCXOJTLDBFE-UHFFFAOYSA-N 0.000 description 2
- 229920001542 oligosaccharide Polymers 0.000 description 2
- 150000002482 oligosaccharides Chemical class 0.000 description 2
- 239000006072 paste Substances 0.000 description 2
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 239000011698 potassium fluoride Substances 0.000 description 2
- 235000003270 potassium fluoride Nutrition 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- 239000011775 sodium fluoride Substances 0.000 description 2
- 235000013024 sodium fluoride Nutrition 0.000 description 2
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 2
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 2
- 229940080313 sodium starch Drugs 0.000 description 2
- CAVXVRQDZKMZDB-UHFFFAOYSA-M sodium;2-[dodecanoyl(methyl)amino]ethanesulfonate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CCS([O-])(=O)=O CAVXVRQDZKMZDB-UHFFFAOYSA-M 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 description 2
- 229960002799 stannous fluoride Drugs 0.000 description 2
- 235000010491 tara gum Nutrition 0.000 description 2
- 239000000213 tara gum Substances 0.000 description 2
- 239000000606 toothpaste Substances 0.000 description 2
- 229940034610 toothpaste Drugs 0.000 description 2
- 229940074410 trehalose Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- 239000000811 xylitol Substances 0.000 description 2
- 235000010447 xylitol Nutrition 0.000 description 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 2
- 229960002675 xylitol Drugs 0.000 description 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 229920000569 Gum karaya Polymers 0.000 description 1
- 235000019082 Osmanthus Nutrition 0.000 description 1
- 241000333181 Osmanthus Species 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- HDSBZMRLPLPFLQ-UHFFFAOYSA-N Propylene glycol alginate Chemical compound OC1C(O)C(OC)OC(C(O)=O)C1OC1C(O)C(O)C(C)C(C(=O)OCC(C)O)O1 HDSBZMRLPLPFLQ-UHFFFAOYSA-N 0.000 description 1
- LKVZSCFGTYHYBT-UHFFFAOYSA-N S(=O)(=O)(O)O.C(CCCCCCCCCCC)(=O)[Na] Chemical compound S(=O)(=O)(O)O.C(CCCCCCCCCCC)(=O)[Na] LKVZSCFGTYHYBT-UHFFFAOYSA-N 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 241000934878 Sterculia Species 0.000 description 1
- 244000228451 Stevia rebaudiana Species 0.000 description 1
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 description 1
- 240000004584 Tamarindus indica Species 0.000 description 1
- 235000004298 Tamarindus indica Nutrition 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229940063953 ammonium lauryl sulfate Drugs 0.000 description 1
- 239000000305 astragalus gummifer gum Substances 0.000 description 1
- CESHKJCQQFFQQQ-UHFFFAOYSA-N azane 2-dodecyl-2-sulfobutanedioic acid Chemical compound N.CCCCCCCCCCCCC(S(O)(=O)=O)(C(O)=O)CC(O)=O CESHKJCQQFFQQQ-UHFFFAOYSA-N 0.000 description 1
- OPVLOHUACNWTQT-UHFFFAOYSA-N azane;2-dodecoxyethyl hydrogen sulfate Chemical compound N.CCCCCCCCCCCCOCCOS(O)(=O)=O OPVLOHUACNWTQT-UHFFFAOYSA-N 0.000 description 1
- ZWXYEWJNBYQXLK-UHFFFAOYSA-N azanium;4-dodecoxy-4-oxo-3-sulfobutanoate Chemical compound [NH4+].CCCCCCCCCCCCOC(=O)C(S(O)(=O)=O)CC([O-])=O ZWXYEWJNBYQXLK-UHFFFAOYSA-N 0.000 description 1
- 229940043430 calcium compound Drugs 0.000 description 1
- 150000001674 calcium compounds Chemical class 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
- 229940079840 cocoyl isethionate Drugs 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- FXNRKXSSLJKNGH-UHFFFAOYSA-L dipotassium;fluoro-dioxido-oxo-$l^{5}-phosphane Chemical compound [K+].[K+].[O-]P([O-])(F)=O FXNRKXSSLJKNGH-UHFFFAOYSA-L 0.000 description 1
- SMVRDGHCVNAOIN-UHFFFAOYSA-L disodium;1-dodecoxydodecane;sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O.CCCCCCCCCCCCOCCCCCCCCCCCC SMVRDGHCVNAOIN-UHFFFAOYSA-L 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 235000010494 karaya gum Nutrition 0.000 description 1
- 239000000231 karaya gum Substances 0.000 description 1
- 229940039371 karaya gum Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- RHFUXPCCELGMFC-UHFFFAOYSA-N n-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl)-n-phenylmethoxyacetamide Chemical compound OC1C(C)(C)OC2=CC=C(C#N)C=C2C1N(C(=O)C)OCC1=CC=CC=C1 RHFUXPCCELGMFC-UHFFFAOYSA-N 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 235000010409 propane-1,2-diol alginate Nutrition 0.000 description 1
- 239000000770 propane-1,2-diol alginate Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 108700004121 sarkosyl Proteins 0.000 description 1
- 239000011257 shell material Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 229940080236 sodium cetyl sulfate Drugs 0.000 description 1
- 229940079776 sodium cocoyl isethionate Drugs 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 229940045998 sodium isethionate Drugs 0.000 description 1
- 229940048106 sodium lauroyl isethionate Drugs 0.000 description 1
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 1
- BRMSVEGRHOZCAM-UHFFFAOYSA-M sodium;2-dodecanoyloxyethanesulfonate Chemical compound [Na+].CCCCCCCCCCCC(=O)OCCS([O-])(=O)=O BRMSVEGRHOZCAM-UHFFFAOYSA-M 0.000 description 1
- GGHPAKFFUZUEKL-UHFFFAOYSA-M sodium;hexadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCOS([O-])(=O)=O GGHPAKFFUZUEKL-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 229940013618 stevioside Drugs 0.000 description 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 235000019202 steviosides Nutrition 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 229940105956 tea-dodecylbenzenesulfonate Drugs 0.000 description 1
- 230000005086 tooth mineralization Effects 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
A kind of flank of tooth cleaning mixture, which is characterized in that comprising 45 mass % or more and 61 mass % median particle diameters below are 5 μm or more and 24 μm calcium carbonate and/or calcirm-fluoride and liquid-like constituents below, and wherein pH value is 9 or more and 10 or less.
Description
Technical field
The flank of tooth that the present invention relates to a kind of for cleaning the flank of tooth (dental surface) is cleaned with mixture (composition (group
At object)).
Background technique
When carrying out daily brush teeth using toothbrush or gear division hospital using dedicated flank of tooth cleaning device to patient's flank of tooth into
When row cleaning, generally all using flank of tooth cleaning mixture.As existing flank of tooth cleaning mixture, such as there are a kind of high
Deploy (mixing) calcium compound concentration it is expected to promote the mixture of flank of tooth calcification again (for example, referring to patent document 1)
Deng.
However, deenergizing in existing flank of tooth cleaning mixture with regard to the tooth dirt and/or removing for color spot (stain) of tooth
For power, there is also rooms for improvement, therefore a kind of flank of tooth is needed to clean the higher flank of tooth cleaning mixture of ability.
In addition, there is also the flank of tooth to clean the more high then easier injury tooth of ability in existing flank of tooth cleaning mixture
The problem of face, therefore the lower flank of tooth cleaning mixture of invasion for needing a kind of pair of flank of tooth to be invaded.
Existing technical literature
Patent document
Patent document 1:(Japan) special open 2013-163656 bulletin.
Summary of the invention
Subject to be solved by the invention
Therefore, problem of the present invention is that, the invasion that a kind of flank of tooth cleaning ability is higher and is invaded to the flank of tooth are provided
Property the cleaning of the lower flank of tooth use mixture.
Means for solving the problems
According to the present invention, a kind of flank of tooth cleaning mixture is provided, which is characterized in that include 45 mass % or more and 61 matter
Measure % median particle diameter below (median diameter) be 5 μm or more and 24 μm calcium carbonate and/or calcirm-fluoride below and
Liquid-like constituents, wherein pH value is 9 or more and 10 or less.
Invention effect
A kind of flank of tooth cleaning of the invention invasion that mixture is that flank of tooth cleaning ability is higher and is invaded to the flank of tooth
Property lower, excellent flank of tooth cleaning use mixture.
Specific embodiment
In flank of tooth cleaning mixture of the invention, as flank of tooth cleaning particle, can mix (allotment) calcium carbonate and/
Or calcirm-fluoride.The reason is that the flank of tooth of calcium carbonate and calcirm-fluoride cleaning ability is higher, and to the invasion that the flank of tooth is invaded
Property is relatively low.
For the combined amount (blending amount) of calcium carbonate and/or calcirm-fluoride in flank of tooth cleaning mixture, need to be 45
Quality % or more and 61 mass % or less.Its reason is that if it is less than 45 mass %, then the flank of tooth cleans ability and is lower, if super
61 mass % are crossed, then the character of cream (paste) is hardened, and operability is deteriorated.More preferably 49 mass % or more and 55 mass % or less.
In addition, the median particle diameter of particle needs to be 5 μm or more and 24 μm or less for calcium carbonate or calcirm-fluoride.Its
The reason is that, the flank of tooth cleans ability and is lower if median particle diameter is less than 5 μm, if it exceeds 24 μm, then the flank of tooth is invaded
Invasion get higher.More preferably, median particle diameter is 8 μm or more and 20 μm or less.
In flank of tooth cleaning mixture of the invention, (addition) can be mixed for improving the carbohydrate of taste.As carbohydrate,
Such as can enumerate: stevioside, xylitol, D-sorbite, oligosaccharides, acesulfame potassium, trehalose, Aspartame, mannitol,
Maltitol, lactitol (stevia, xylitol, sorbitol, oligosaccharides, acesulfame
Potassium, trehalose, aspartame, mannitol, maltitol, lactitol) etc..Can be used alone these sugar
Any one in class can also be used in mixed way any two or more carbohydrate therein.
For the combined amount (blending amount) of the carbohydrate in flank of tooth cleaning mixture, preferably 1 mass % or more and 5 matter
Measure % or less.Its reason is, by for 1 mass % or more, can improve the taste of cream and be easy to use, by for 5 mass % with
Under, frank sense can be kept.
In flank of tooth cleaning mixture of the invention, (addition) can be mixed for adjusting the binder of viscosity.As viscous
Tie agent, such as can enumerate: mosanom, propylene glycol alginate, carboxymethyl cellulose, sodium carboxymethylcellulose, carboxymethyl are fine
Tie up plain calcium, sodium starch glycollate, starch phosphate sodium, Sodium Polyacrylate, carboxypolymethylene, methylcellulose, avicel cellulose,
Hydroxyethyl cellulose, hydroxypropyl cellulose, starch, polyvinylpyrrolidone, guar gum, OK a karaoke club tie up bean gum, tara gum, Luo Wang
Sub- glue, Arabic gum, bassora gum, Karaya Gum, alginic acid, carrageenan, xanthan gum, gellan gum, curdlan, lactose, shell
Polysaccharide, chitosan (sodium alginate, alginic acid propylene glycol ester, carboxymethyl
cellulose、sodium carboxymethyl cellulose、calcium carboxymethyl cellulose、
sodium starch glycolate、sodium starch phosphate ester、sodium polyacrylate、
carboxypolymethylene、methyl cellulose、crystalline cellulose、hydroxyethyl
cellulose、hydroxypropyl cellulose、starch、polyvinyl pyrrolidone、guar gum、
karavi bean gum、tara gum、tamarind seed gum、gum arabic、tragacanth gum、karaya
gum、alginic acid、carrageenan、xanthan gum、gellan gum、curdlan、lactose、chitin、
Chitosan, chitosamine) etc. water soluble polymer.Any one that can be used alone in these binders, can also be right
Any two or more binder therein is used in mixed way.
For the combined amount (blending amount) of the binder in flank of tooth cleaning mixture, preferably 0.1 mass % or more
And 1 below mass %.Its reason is, by for 0.1 mass % or more, cream can have the viscosity for being easy to invest on toothbrush, by
For 1 mass % hereinafter, cream can have the hardness appropriate for being easy to come out from pipe (tube).
In flank of tooth cleaning mixture of the invention, the fluorine compounds of (addition) other than calcirm-fluoride can be mixed.It is logical
Addition fluorine compounds are crossed, fluorine ion can be supplied into oral cavity, and there is better prevention of dental caries effect.Except calcirm-fluoride
Fluorine compounds, such as can enumerate: sodium fluoride, potassium fluoride, ammonium fluoride, stannous fluoride, sodium monofluorophosphate, single fluorophosphoric acid potassium
(sodium fluoride、potassium fluoride、ammonium fluoride、stannous fluoride、
Sodium monofluorophosphate, potassium monofluorophosphate) etc..Can be used alone these fluorine
Any one in compound can also be used in mixed way any two or more fluorine compounds therein.
For the combined amount (blending amount) of the fluorine compounds except the calcirm-fluoride in flank of tooth cleaning mixture, preferably
0.025 mass % or more and 0.9 mass % or less.Its reason is, by for 0.025 mass % or more, can have better dental caries
Tooth preventive effect, by for 0.9 mass % hereinafter, when routine use, will not have an impact raw body (for example, human body).
In flank of tooth cleaning mixture of the invention, (addition) preservative can be mixed.As preservative, such as can enumerate
Out: ethyl-para-hydroxybenzoate, methyl p-hydroxybenzoate (ethylparaben, methylparaben) etc..It can be used alone
Any one in these preservatives can also be used in mixed way any two or more preservative therein.
For the combined amount (blending amount) of the preservative in flank of tooth cleaning mixture, preferably 0.1 mass % or more
And 0.3 below mass %.The reason is that can have better anti-corrosion effect by for 0.1 mass % or more, by being 0.3
Quality % hereinafter, when routine use raw body (for example, human body) will not be had an impact.
In flank of tooth cleaning mixture of the invention, (addition) liquid-like constituents can be mixed.It, can by adding liquid-like constituents
It has an effect as solvent, to carry out livering.In addition, being alternatively arranged as wetting agent and playing a role.As liquid-like constituents, such as
It can enumerate: polyethylene glycol, ethylene glycol, propylene glycol, glycerol, chondroitin sulfate (polyethylene glycol, ethylene
Glycol, propylene glycol, glycerin, chondroitin sulfate) or its salt etc., water etc..It can be used alone
Any one in these liquid-like constituents can also be used in mixed way any two or more liquid-like constituents therein.
For the combined amount (blending amount) of the liquid-like constituents in flank of tooth cleaning mixture, preferably 20 mass % or more
And 54 below mass %.Its reason is, by for 20 mass % or more, can be changed to soft paste, by for 54 mass % with
Under, drippage is difficult to happen when investing toothbrush etc. above.More preferably 30 mass % or more and 45 mass % or less.
In flank of tooth cleaning mixture of the invention, (addition) surface (interface) activating agent can be mixed.Pass through mixture table
Face activating agent, flank of tooth cleaning mixture can be improved cleans (cleaning) effect and/or foaming effect.As surfactant,
Such as it can enumerate: lauroyl sodium sulfate, sodium lauroyl sarcosine, sodium lauroylmethyl taurate, lauryl betaine, 16
Sodium alkyl sulfate, sodium lauryl tri(oxyethyl) sulfate, lauryl sulfosuccinic acid ammonium, Texapon Special, Zetesol AP, the moon
Osmanthus acyl sodium isethionate, neopelex, dodecyl benzene sulfonic acid triethanolamine, cocoyl isethionate
(sodium lauryl sulfate、sodium lauroyl sarcosinate、sodium lauroyl methyl
taurate、lauryl betaine、sodium cetyl sulfate、sodium lauryl ether sulfate、
ammonium lauryl sulfosuccinate、ammonium lauryl sulfate、ammonium lauryl ether
sulfate、sodium lauroyl isethionate、sodium dodecyl benzene sulfonate、
Triethanolamine dodecylbenzenesulfonate, sodium cocoyl isethionate) etc..
For flank of tooth cleaning mixture of the invention, viscosity is suitable when being 80~400Pas at 25 DEG C (temperature)
It in being used in oral cavity, therefore is preferred.More preferably, the viscosity at 25 DEG C is 150~250Pas.
In flank of tooth cleaning mixture of the invention, (addition) can be mixed for adjusting the tackifier of viscosity.As increasing
Stick, such as can enumerate: the silica chemical combination of silicic acid anhydride (silicic anhydride), silica gel (silica gel) etc.
Object (silica compound).
For flank of tooth cleaning mixture of the invention, pH value needs to be 9 or more and 10 or less.The reason is that
If pH, less than 9, the flank of tooth cleans ability and is lower, the stimulation meeting if pH value is more than 10, when using in oral cavity to oral cavity
Become larger.
In flank of tooth cleaning mixture of the invention, can also properly mix (addition) colorant, preservative agent, mould inhibitor,
The additive of fragrance etc..
[embodiment]
The present invention is described in detail with reference to embodiments, but the present invention is not limited to embodiments below.
1 > of < embodiment
As shown in table 1, to the calcium carbonate of 53 mass % (median particle diameter: 10 μm), the D-sorbite of 3 mass %, 0.6 matter
Measure sodium monofluorophosphate, the 0.2 mass % of the sodium carboxymethylcellulose of %, the hydroxyethyl cellulose of 0.8 mass %, 0.5 mass %
Methyl p-hydroxybenzoate, the silicic acid anhydride of 0.4 mass %, the purified water of 24.5 mass %, 16 mass % glycerol and 1 matter
The fragrance of amount % is deployed (mixing), and is kneaded using mixing machine, has thus been made the flank of tooth paste and has been cleaned with mixing
Object.
< embodiment 2~5 and the Comparative Examples 1 to 5 >
Using constituent shown in table 1, and by method similarly to Example 1, the flank of tooth paste is made and has cleaned
Use mixture.
[table 1]
[pH value measurement]
For various flank of tooth cleaning mixtures, using pH value analyzer (" hole field makes institute " corporation, D-52) measurement
PH value.As a result shown in table 1.
[median particle diameter of calcium carbonate or calcium fluoride particles]
Using laser diffraction/scattering formula particle size distribution analyzer, the intermediate value grain of calcium carbonate or calcium fluoride particles is determined
Diameter (volume reference).
[invasion that the flank of tooth is invaded]
In order to which the invasion invaded to the flank of tooth to various flank of tooth cleaning mixtures is evaluated, implement as follows
Test.
Using waterproof paper (#4000) and 3 μ of diamond cream, 1 μ and soft object (buff) to ox tooth enamel (enamel) matter surface
Mirror ultrafinish is carried out, using as test film.
Then, for the lapped face of test film, using the various flank of tooth cleaning mixtures of 0.1g, and it is clear using the flank of tooth
It sweeps and is carried out under conditions of 1940rpm and 1 minute with rubber cup (rubber cup) (" GC society " corporation, PTC Cup II)
Flank of tooth cleaning.
For the position for having carried out flank of tooth cleaning, using laser microscope (laser microscope) (" Keyence society "
Corporation, VK-X200) arithmetic surface roughness (Ra) is determined.
The aggressive evaluation index invaded to the flank of tooth is as described below.As a result shown in table 1.
Fine: Ra is less than 0.10 μm
Preferable: Ra is 0.10 μm more than and less than 0.15 μm
Bad: Ra is 0.15 μm or more
[flank of tooth cleaning ability]
It is evaluated in order to which the flank of tooth to various flank of tooth cleaning mixtures cleans ability, has carried out following test.
After being ground using waterproof paper (#4000) to ox tooth enamel surface, it is immersed in ferric tannate (iron
Tannate it is) 10 minutes in the coloring liquid of principal component, color spot (stain) deposition (deposition) has been carried out, using as test
Piece.Later, the color of the test film is determined using spectral photometric colour measuring meter (" Konicaminolta society " corporation, CM-700d).
Then, it for test film, is brushed using the various flank of tooth cleaning mixtures of 0.1g, and using flank of tooth cleaning with PTC
(brush), under conditions of 1940rpm and 30 second, flank of tooth cleaning has been carried out.
For the position for having carried out flank of tooth cleaning, color is determined using spectral photometric colour measuring meter, and calculate the flank of tooth
Clean the color difference Δ E*ab of the L*a*b* color space of front and back.
The evaluation index that the flank of tooth cleans ability is as described below.As a result shown in table 1.
Fine: Δ E*ab is 10 or more
Preferable: Δ E*ab is 5 more than and less than 10
Bad: Δ E*ab is less than 5
Confirmed by table 1, for the flank of tooth of the invention is cleaned with mixture, invasion that the flank of tooth is invaded compared with
It is low, and flank of tooth cleaning ability is also higher.
Based on above-mentioned, the present invention provides a kind of flank of tooth cleaning mixture, which is characterized in that comprising 45 mass % or more and
61 mass % median particle diameters below be 5 μm or more and 24 μm calcium carbonate and/or calcirm-fluoride and liquid-like constituents below, wherein
PH value is 9 or more and 10 or less.
Embodiments of the present invention are illustrated above, but above content is not to carry out to the contents of the present invention
The content of restriction.
Claims (1)
1. a kind of flank of tooth clean with mixture, characterized by comprising:
45 mass % or more and 61 mass % median particle diameters below are 5 μm or more and 24 μm of calcium carbonate below and/or fluorination
Calcium；And
Liquid-like constituents,
Wherein, pH value is 9 or more and 10 or less.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311044374.9A CN116919835A (en) | 2017-07-25 | 2018-07-23 | Tooth surface cleaning mixture |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017143546A JP7126811B2 (en) | 2017-07-25 | 2017-07-25 | Tooth cleaning composition |
| JP2017-143546 | 2017-07-25 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311044374.9A Division CN116919835A (en) | 2017-07-25 | 2018-07-23 | Tooth surface cleaning mixture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109288696A true CN109288696A (en) | 2019-02-01 |
Family
ID=65167828
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810812006.7A Pending CN109288696A (en) | 2017-07-25 | 2018-07-23 | Mixture is used in flank of tooth cleaning |
| CN202311044374.9A Pending CN116919835A (en) | 2017-07-25 | 2018-07-23 | Tooth surface cleaning mixture |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311044374.9A Pending CN116919835A (en) | 2017-07-25 | 2018-07-23 | Tooth surface cleaning mixture |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP7126811B2 (en) |
| KR (1) | KR102108005B1 (en) |
| CN (2) | CN109288696A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54157843A (en) * | 1978-05-25 | 1979-12-13 | Colgate Palmolive Co | Dental cream composition |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS582921B2 (en) * | 1973-03-20 | 1983-01-19 | ライオン株式会社 | toothpaste |
| JPS60146814A (en) * | 1983-12-29 | 1985-08-02 | Lion Corp | Tooth paste composition |
| KR101169939B1 (en) * | 2004-07-06 | 2012-08-06 | 라이온 가부시키가이샤 | Dentifrice composition |
| KR101490782B1 (en) * | 2008-10-14 | 2015-02-09 | 주식회사 엘지생활건강 | Toothpaste composition |
| JP2013163656A (en) | 2012-02-10 | 2013-08-22 | Gc Corp | Dentifrice |
| CN104981273B (en) * | 2012-12-24 | 2018-03-13 | 高露洁-棕榄公司 | Oral care composition |
| EP3166572B1 (en) * | 2014-07-10 | 2019-05-01 | The Procter and Gamble Company | Anti-calculus oral compositions |
| JP6451562B2 (en) * | 2015-09-07 | 2019-01-16 | ライオン株式会社 | Oral composition |
-
2017
- 2017-07-25 JP JP2017143546A patent/JP7126811B2/en active Active
-
2018
- 2018-07-23 CN CN201810812006.7A patent/CN109288696A/en active Pending
- 2018-07-23 CN CN202311044374.9A patent/CN116919835A/en active Pending
- 2018-07-24 KR KR1020180086228A patent/KR102108005B1/en active IP Right Grant
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54157843A (en) * | 1978-05-25 | 1979-12-13 | Colgate Palmolive Co | Dental cream composition |
Non-Patent Citations (1)
| Title |
|---|
| 裘炳毅，高志红: "《现代化妆品科学与技术》", 31 March 2016, 中国轻工业出版社 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019026555A (en) | 2019-02-21 |
| CN116919835A (en) | 2023-10-24 |
| KR20190011696A (en) | 2019-02-07 |
| JP7126811B2 (en) | 2022-08-29 |
| KR102108005B1 (en) | 2020-05-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI539969B (en) | Composition for oral use | |
| CA2629812A1 (en) | Stannous salt and sodium tripolyphosphate oral care compositions and methods | |
| CN103957878B (en) | Dentrifice composition | |
| JP2010280616A (en) | Dentifrice | |
| EP3142636A1 (en) | Dentifrice compositions having dental plaque mitigation or improved fluoride uptake | |
| EP3082715A1 (en) | Oral care compositions comprising calcium carbonate and talc | |
| JP5627074B2 (en) | Dentifrice composition | |
| CA2946205A1 (en) | Dentifrice compositions having improved fluoride ion stability or fluoride uptake | |
| TWI746667B (en) | Oral composition | |
| JP6716554B2 (en) | Dental polishing paste and dental cleaning paste | |
| CN109288696A (en) | Mixture is used in flank of tooth cleaning | |
| JP7165772B2 (en) | Tooth surface cleaning composition | |
| JP2004284956A (en) | Toothpaste composition | |
| EP3510990A1 (en) | Oral composition | |
| JP2013006784A (en) | Dentifrice composition | |
| JP2016102069A (en) | Method for cleaning tooth surface, composition for cleaning tooth surface and method for using the same | |
| JP2009242241A (en) | Dentifrice | |
| JP2017218436A (en) | Skin cosmetics | |
| JP6038563B2 (en) | Oral composition | |
| TWI746627B (en) | Intraoral tartar dispersant | |
| JP2007505863A (en) | Composition comprising a soluble calcium sequestering agent | |
| CN110650722A (en) | Dentifrice composition | |
| AU2011371265B2 (en) | Oral care compositions | |
| JP2005298498A (en) | Composition for oral cavity | |
| EP3373890B1 (en) | Dentifrice compositions with improved fluoride stability |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190201 |
|
| RJ01 | Rejection of invention patent application after publication |