KR102108005B1 - Composition for dental cleaning - Google Patents

Abstract

The present invention provides a composition for cleaning a tooth surface having a high tooth surface cleaning ability and a low invasiveness to the tooth surface.
The present invention includes at least one of calcium carbonate and calcium fluoride having a median diameter of 5 µm or more and 24 µm or less in a ratio of 45% by mass or more and 61% by mass or less, further comprising a liquid component, and having a pH of 9 or more and 10 or less. It is a tooth cleaning composition characterized by the above.

Description

Composition for cleaning tooth surfaces {COMPOSITION FOR DENTAL CLEANING}

The present invention relates to a tooth cleaning composition used to clean the tooth surface.

When cleaning teeth of a patient using a toothbrush or using a dedicated tooth cleaning tool in a dental clinic, a tooth cleaning composition is used. In the conventional tooth surface cleaning composition, for example, there is expected to promote the recalcification of the tooth surface by mixing a calcium compound at a high concentration (for example, see Patent Document 1).

However, in the conventional tooth cleaning composition, there is room for improvement in the ability to remove dental plaque and staining contamination (discoloration), and thus a tooth cleaning composition having a higher tooth cleaning ability has been required.

In addition, the conventional tooth cleaning composition has a problem that the higher the tooth cleaning ability, the more easily the tooth surface is damaged, and thus a tooth cleaning composition having a lower invasiveness to the tooth surface has been required.

Japanese Patent Application Publication No. 2013-163656

Accordingly, an object of the present invention is to provide a composition for cleaning a tooth surface having a high tooth cleaning ability and a low invasiveness to the tooth surface.

According to the present invention, at least one of calcium carbonate and calcium fluoride having a median diameter of 5 µm or more and 24 µm or less is included in a ratio of 45% by mass or more and 61% by mass or less, and further includes a liquid component, and the pH is Provided is a tooth cleaning composition characterized in that it is 9 or more and 10 or less.

The tooth cleaning composition according to the present invention is an excellent tooth cleaning composition with high tooth cleaning ability and low invasiveness to the tooth surface.

In the tooth cleaning composition according to the present invention, calcium carbonate and / or calcium fluoride may be blended as the tooth cleaning particles. This is because calcium carbonate and calcium fluoride have a high cleaning surface and low invasiveness to the surface.

It is necessary that the blending amount of calcium carbonate and / or calcium fluoride in the tooth cleaning composition is 45% by mass or more and 61% by mass or less. This is because if the amount is less than 45% by mass, the cleaning ability becomes low, and when it exceeds 61% by mass, the properties of the paste become hard, resulting in poor operability. More preferably, it is 49 mass% or more and 55 mass% or less.

In addition, calcium carbonate or calcium fluoride needs to have a median diameter of 5 µm or more and 24 µm or less. This is because if the median diameter is less than 5 μm, the tooth cleaning ability is lowered, and if it exceeds 24 μm, the invasiveness to the tooth surface is increased. More preferably, the median diameter is 8 µm or more and 20 µm or less.

Sugar composition may be added to the tooth cleaning composition according to the present invention to improve taste. Sugars include, for example, stevia, xylitol, sorbitol, oligosaccharides, acesulfame potassium, trehalose, aspartame, mannitol (mannitol), maltitol, and lactitol. These may be single or a combination of two or more.

It is preferable that the blending amount of saccharides in the tooth cleaning composition is 1% by mass or more and 5% by mass or less. By setting the content to 1% by mass or more, the taste of the paste is improved and easy to use, and by setting the content to 5% by mass or less, a refreshing feeling can be maintained.

In the composition for cleaning a tooth surface according to the present invention, a caking agent may be blended for viscosity adjustment. Examples of the caking agent include sodium alginate, propylene glycol alginate, carboxymethylcellulose, sodium carboxymethylcellulose, calcium carboxymethylcellulose, sodium starch glycolate, sodium starch phosphate, sodium polyacrylate, carboxypolymethylene, methyl Cellulose, crystalline cellulose, hydroxyethylcellulose, hydroxypropylcellulose, starch, polyvinylpyrrolidone, guar gum, carob bean gum, tara gum, tamarind seed gum (tamarind sead gum), arabic gum, tragacanth gum, karaya gum, alginic acid, carrageenan, xanthan gum, gellan gum water-soluble polymers such as gum, curdlan, lactose, chitin, chitosan, and chitosamine. These may be single or a combination of two or more.

It is preferable that the blending amount of a caking additive in a tooth cleaning composition is 0.1 mass% or more and 1 mass% or less. This is because, when the content is 0.1% by mass or more, the paste has a viscosity that is easy to take on the toothbrush, and when it is 1% by mass or less, the paste has an appropriate hardness for easy removal from the tube.

Fluorine compounds other than calcium fluoride can be added to the tooth cleaning composition according to the present invention. By blending the fluorine compound, fluoride ions are supplied into the oral cavity, and the effect of preventing tooth decay is further expected. Examples of the fluorine compound other than calcium fluoride include sodium fluoride, potassium fluoride, ammonium fluoride, stannous fluoride, sodium monofluorophosphate, and potassium monofluorophosphate. These may be single or a combination of two or more.

It is preferable that the compounding amount of fluorine compounds other than calcium fluoride in the tooth cleaning composition is 0.025% by mass or more and 0.9% by mass or less. This is because the effect of preventing dental caries is expected to be 0.025% by mass or more, and by 0.9% by mass or less, there is no effect on the living body even when used in daily life.

Preservatives may be added to the tooth cleaning composition according to the present invention. As a preservative, ethyl paraben, methyl paraben, etc. are mentioned, for example. These may be single or a combination of two or more.

It is preferable that the blending amount of the preservative in the composition for interfacial cleaning is 0.1 mass% or more and 0.3 mass% or less. This is because the effect of preventing corrosion is expected by setting the content to 0.1% by mass or more, and even if it is used in daily life by 0.3% by mass or less, there is no effect on the living body.

The liquid composition is formulated in the tooth cleaning composition according to the present invention. By blending the liquid component, it can function as a solvent and be pasted. It also functions as a wetting agent. Examples of the liquid component include polyethylene glycol, ethylene glycol, propylene glycol, glycerin, chondroitin sulfate or salts thereof, and water. These may be single or a combination of two or more.

It is preferable that the blending amount of the liquid component in the tooth cleaning composition is 20% by mass or more and 54% by mass or less. It is because it becomes a soft paste form by setting it as 20 mass% or more, and when it is set as 54 mass% or less, it becomes difficult to hang when put on a toothbrush or the like. More preferably, it is 30 mass% or more and 45 mass% or less.

Surfactant may be added to the tooth cleaning composition according to the present invention. By adding a surfactant, the cleaning effect of the composition for cleaning a tooth surface, the foaming effect, and the like can be improved. As the surfactant, for example, sodium lauryl sulfate, sodium lauroyl sarcosinate, sodium lauroyl methyl taurate, lauryl betaine, sodium cetyl sulfate, sodium lauryl ether sulfate, sodium lauryl sulfophosphate, ammonium lauryl sulfate And ammonium, lauryl ether ammonium sulfate, sodium lauroyl isethionate, sodium dodecylbenzenesulfonate, triethanolamine dodecylbenzenesulfonate, and sodium cocoyl isethionate.

The composition for cleaning a tooth surface according to the present invention is preferable in that a viscosity of 80 to 400 Pa · s at 25 ° C. is suitable for intraoral use. More preferably, it is 150 to 250 Pa · s at 25 ° C.

In the composition for cleaning a tooth surface according to the present invention, a thickener may be blended for viscosity adjustment. Examples of the thickener include silica-based compounds such as silicic anhydride and silica gel.

The tooth cleaning composition according to the present invention needs to have a pH of 9 or more and 10 or less. This is because when the pH is less than 9, the cleaning ability is low, and when the pH exceeds 10, the irritation is large when used in the oral cavity.

To the tooth cleaning composition according to the present invention, additives such as colorants, preservatives, antifungal agents, fragrances and the like may be suitably blended as necessary.

Example

Hereinafter, the present invention will be described in detail with reference to examples, but the present invention is not limited to the following examples.

<Example 1>

As shown in Table 1, calcium carbonate (central diameter: 10 µm) 53 mass%, sorbitol 3 mass%, carboxymethylcellulose sodium 0.6 mass%, hydroxyethylcellulose 0.8 mass%, sodium monofluorophosphate 0.5 mass%, Methylparaben 0.2 mass%, anhydrous silicic acid 0.4 mass%, purified water 24.5 mass%, glycerin 16 mass% and fragrance 1 mass% were blended and kneaded using a mixer to prepare a paste-like toothbrush cleaning composition.

<Examples 2 to 5 and Comparative Examples 1 to 5>

According to the composition shown in Table 1, a paste-like tooth cleaning composition was prepared in the same manner as in Example 1.

[pH measurement]

For each tooth cleaning composition, pH was measured using a pH meter (Horiba, D-52). Table 1 shows the results.

[Median diameter of calcium carbonate or calcium fluoride particles]

The median diameter (volume basis) of the calcium carbonate or calcium fluoride particles was measured using a laser diffraction / scattering particle diameter distribution measuring apparatus.

[Invasiveness to tooth surface]

The following tests were conducted to evaluate the invasiveness to the tooth surface in each tooth cleaning composition.

The enameled surface of the bovine teeth was polished by using a water-repellent paper # 4000 and 3 μ · 1 μ of diamond paste and a buff to prepare a test piece.

Subsequently, with respect to the polishing surface of the test piece, 0.1 g of each tooth cleaning composition was used, and tooth cleaning was performed at 1940 rpm and 1 minute using a rubber cup for cleaning teeth (GC, PTC Cup II).

For the surface cleaned, arithmetic surface roughness (Ra) was measured using a laser microscope (Kiens, VK-X200).

The indicators for evaluating the invasiveness to the tooth surface are as follows. Table 1 shows the results.

Very good: Ra less than 0.10㎛

Good: Ra is 0.10 µm or more but less than 0.15 µm

Bad: Ra is 0.15㎛ or more

[Hip cleaning ability]

The following tests were conducted to evaluate the tooth cleaning ability of each tooth cleaning composition.

After polishing on the enameled surface of a cow's tooth with water-resistant paper # 4000, it was immersed in a coloring solution containing iron tannate as a main component for 10 minutes to prepare a test piece by depositing discoloration. The color of this test piece was measured using a spectrophotometer (Konica Minolta, CM-700d).

Subsequently, 0.1 g of each tooth cleaning composition was used for the test piece, and the tooth cleaning was performed at a condition of 1940 rpm and 30 seconds using a PTC brush for cleaning the tooth.

The color was measured on the surface cleaned by using a spectrophotometer, and the color difference (ΔE ^* ab) in L ^* , a ^* , and b ^* color spaces before and after the surface cleaning was calculated.

The evaluation index of the tooth cleaning ability is as follows. Table 1 shows the results.

Very good: ΔE ^* ab greater than 10

Good: ΔE ^* ab is 5 or more but less than 10

Bad: ΔE ^* ab less than 5

From Table 1, it can be seen that the composition for cleaning a tooth surface according to the present invention has a high ability to clean the tooth surface while being less invasive to the tooth surface.

The embodiments according to the present invention have been described above, but the above contents do not limit the contents of the present invention.

This application claims the priority of Japanese Patent Application No. 2017-143546 filed on July 25, 2017 to the Japan Patent Office, and the entire contents thereof are incorporated herein by reference.

Claims (5)

At least one of calcium carbonate and calcium fluoride having a median diameter of 5 µm or more and 24 µm or less at a ratio of 45% to 61% by mass,
It further comprises a liquid component comprising water and at least one selected from polyethylene glycol, ethylene glycol, propylene glycol, glycerin, chondroitin sulfate, or salts thereof,
pH is 9 or more and 10 or less,
The content of the liquid component is 20% by mass or more and 54% by mass or less,
The water content of the toothbrush cleaning composition, characterized in that less than 24.5% by mass. According to claim 1, Stevia (stevia), xylitol (xylitol), sorbitol (sorbitol), oligosaccharides, acesulfame potassium (acesulfame potassium), trehalose (trehalose), aspartame (aspartame), mannitol (mannitol) ), Maltitol (maltitol), and at least one saccharide selected from lactitol (lactitol) further comprises,
The content of the saccharides is a toothbrush cleaning composition, characterized in that 1% by mass or more and 5% by mass or less. [3] The composition for cleaning a tooth surface according to claim 1 or 2, wherein the liquid component contains glycerin. 3. The composition for cleaning a tooth surface according to claim 2, wherein the saccharide comprises xylitol. 4. The toothbrush cleaning composition according to claim 3, wherein the saccharide comprises xylitol.