JP7126811B2 - Tooth cleaning composition - Google Patents
Tooth cleaning composition Download PDFInfo
- Publication number
- JP7126811B2 JP7126811B2 JP2017143546A JP2017143546A JP7126811B2 JP 7126811 B2 JP7126811 B2 JP 7126811B2 JP 2017143546 A JP2017143546 A JP 2017143546A JP 2017143546 A JP2017143546 A JP 2017143546A JP 7126811 B2 JP7126811 B2 JP 7126811B2
- Authority
- JP
- Japan
- Prior art keywords
- tooth surface
- mass
- surface cleaning
- cleaning composition
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000007788 liquid Substances 0.000 claims description 10
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- 239000000213 tara gum Substances 0.000 description 1
- 229940105956 tea-dodecylbenzenesulfonate Drugs 0.000 description 1
- 229940074410 trehalose Drugs 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Description
本発明は、歯面を清掃するために用いられる歯面清掃用組成物に関する。 TECHNICAL FIELD The present invention relates to a tooth surface cleaning composition used for cleaning tooth surfaces.
歯ブラシを用いた通常の歯磨きの際、あるいは歯科医院における専用の歯面清掃器具を使用した患者の歯面クリーニングの際には歯面清掃用組成物が用いられている。従来の歯面清掃用組成物としては、例えば、カルシウム化合物を高濃度に配合し歯面の再石灰化の促進を期待したもの（例えば、特許文献１参照。）等が存在する。 BACKGROUND ART A tooth surface cleaning composition is used during normal tooth brushing using a toothbrush or during tooth surface cleaning of a patient using a dedicated tooth surface cleaning instrument at a dental clinic. As a conventional tooth surface cleaning composition, for example, there is a composition expected to promote remineralization of the tooth surface by blending a calcium compound at a high concentration (see, for example, Patent Document 1).
しかしながら、従来の歯面清掃用組成物においては、歯の歯垢や着色汚れ（ステイン）の除去能力において改善の余地があり、より歯面清掃能力の高い歯面清掃用組成物が求められていた。
また、従来の歯面清掃用組成物において、歯面清掃能力が高いものほど歯面を傷つけてしまいやすい問題があり、より歯面への侵襲性の低い歯面清掃用組成物が求められていた。
However, conventional tooth surface cleaning compositions have room for improvement in their ability to remove plaque and stains from teeth, and there is a demand for tooth surface cleaning compositions with higher tooth surface cleaning ability. rice field.
In addition, conventional tooth surface cleaning compositions have a problem that the higher the tooth surface cleaning ability, the more likely they are to damage the tooth surface. rice field.
そこで本発明は、歯面清掃能力が高く、且つ歯面への侵襲性が低い歯面清掃用組成物を提供することを課題とする。 Accordingly, an object of the present invention is to provide a tooth surface cleaning composition that has high tooth surface cleaning ability and low invasiveness to the tooth surface.
本発明によれば、メジアン径が５μｍ以上２４μｍ以下であるカルシウム化合物及び液状成分を含み、前記カルシウム化合物は、炭酸カルシウム及び／又はフッ化カルシウムであり、前記カルシウム化合物の含有量が４９質量％以上６１質量％以下であり、前記液状成分は、ポリエチレングリコール、エチレングリコール、プロピレングリコール、グリセリン、コンドロイチン硫酸及びその塩、並びに水の１種以上からなり、前記液状成分の含有量が３４．１質量％以上であり、且つｐＨが９以上１０以下であることを特徴とする歯面清掃用組成物が提供される。
According to the present invention, a calcium compound having a median diameter of 5 μm or more and 24 μm or less and a liquid component are included, the calcium compound is calcium carbonate and/or calcium fluoride, and the content of the calcium compound is 49% by mass or more. 61% by mass or less, the liquid component is composed of one or more of polyethylene glycol, ethylene glycol, propylene glycol, glycerin, chondroitin sulfate and its salts, and water, and the content of the liquid component is 34.1% by mass. and a pH of 9 or more and 10 or less.
本発明に係る歯面清掃用組成物は、歯面清掃能力が高く、且つ歯面への侵襲性が低い優れた歯面清掃用組成物である。 INDUSTRIAL APPLICABILITY The tooth surface cleaning composition according to the present invention is an excellent tooth surface cleaning composition having high tooth surface cleaning ability and low invasiveness to the tooth surface.
本発明に係る歯面清掃用組成物には、歯面清掃用の粒子として、炭酸カルシウム及び／又はフッ化カルシウムを配合することができる。炭酸カルシウム及びフッ化カルシウムは歯面清掃能力が高く、歯面への侵襲性が低いためである。 The tooth surface cleaning composition according to the present invention may contain calcium carbonate and/or calcium fluoride as tooth surface cleaning particles. This is because calcium carbonate and calcium fluoride have a high ability to clean tooth surfaces and are less invasive to tooth surfaces.
歯面清掃用組成物中の炭酸カルシウム及び／又はフッ化カルシウムの配合量は４５質量％以上６１質量％以下であることが必要である。４５質量％未満であると、歯面清掃能力が低くなり、６１質量％を超えると、ペーストの性状が硬くなり操作性が悪くなるためである。より好ましくは、４９質量％以上５５質量％以下である。 The content of calcium carbonate and/or calcium fluoride in the tooth surface cleaning composition should be 45% by mass or more and 61% by mass or less. If it is less than 45% by mass, the tooth surface cleaning ability will be low, and if it exceeds 61% by mass, the properties of the paste will be hard and the operability will be poor. More preferably, it is 49% by mass or more and 55% by mass or less.
また炭酸カルシウム又はフッ化カルシウムは、その粒子のメジアン径が５μｍ以上２４μｍ以下であることが必要である。メジアン径が５μｍ未満であると、歯面清掃能力が低くなり、２４μｍを超えると、歯面への侵襲性が高くなるためである。より好ましくは、メジアン径が８μｍ以上２０μｍ以下である。 Calcium carbonate or calcium fluoride must have a median particle diameter of 5 μm or more and 24 μm or less. This is because if the median diameter is less than 5 μm, the tooth surface cleaning ability will be low, and if it exceeds 24 μm, the invasiveness to the tooth surface will be high. More preferably, the median diameter is 8 μm or more and 20 μm or less.
本発明に係る歯面清掃用組成物には、味の改善のために糖類を配合することができる。糖類としては、例えば、ステビア，キシリトール，ソルビトール，オリゴ糖，アセスルファムカリウム，トレハロース，アスパルテーム、マンニトール，マルチトール，ラクチトール等が挙げられる。これらは単独でも２種以上配合してもよい。 The tooth surface cleaning composition according to the present invention may contain sugars to improve taste. Examples of sugars include stevia, xylitol, sorbitol, oligosaccharides, acesulfame potassium, trehalose, aspartame, mannitol, maltitol, lactitol and the like. These may be used alone or in combination of two or more.
歯面清掃用組成物中の糖類の配合量は１質量％以上５質量％以下であることが好ましい。１質量％以上であることによりペーストの味が改善され使用しやすくなり、５質量％以下であることにより爽快感が保たれるためである。 The amount of saccharide compounded in the tooth surface cleaning composition is preferably 1% by mass or more and 5% by mass or less. This is because when the amount is 1% by mass or more, the taste of the paste is improved and it becomes easier to use, and when the amount is 5% by mass or less, a refreshing feeling is maintained.
本発明に係る歯面清掃用組成物には、粘度の調整のために粘結剤を配合することができる。粘結剤としては、例えば、アルギン酸ナトリウム，アルギン酸プロピレングリコールエステル，カルボキシメチルセルロース，カルボキシメチルセルロースナトリウム，カルボキシメチルセルロースカルシウム，デンプングリコール酸ナトリウム，デンプンリン酸エステルナトリウム，ポリアクリル酸ナトリウム，カルボキシポリメチレン，メチルセルロース，結晶セルロース，ヒドロキシエチルセルロース、ヒドロキシプロピルセルロース，デンプン、ポリビニルピロリドン，グァーガム，カジブビーンガム，タラガム，タマリンドシードガム，アラビアガム，トラガントガム，カラヤガム，アルギン酸，カラギナン，キサンタンガム，ジェランガム，カードラン，ラクトース，キチン，キトサン，キトサミン等の水溶性高分子が挙げられる。これらは単独でも２種以上配合してもよい。 The tooth surface cleaning composition according to the present invention may contain a binder for viscosity adjustment. Examples of binding agents include sodium alginate, propylene glycol alginate, carboxymethyl cellulose, sodium carboxymethyl cellulose, calcium carboxymethyl cellulose, sodium starch glycolate, sodium starch phosphate, sodium polyacrylate, carboxypolymethylene, methyl cellulose, crystalline Cellulose, hydroxyethylcellulose, hydroxypropylcellulose, starch, polyvinylpyrrolidone, guar gum, kazib bean gum, tara gum, tamarind seed gum, gum arabic, tragacanth gum, karaya gum, alginic acid, carrageenan, xanthan gum, gellan gum, curdlan, lactose, chitin, chitosan, chitosamine, etc. of water-soluble polymers. These may be used alone or in combination of two or more.
歯面清掃用組成物中の粘結剤の配合量は０．１質量％以上１質量％以下であることが好ましい。０．１質量％以上であることによりペーストが歯ブラシに採取しやすい粘性を有し、１質量％以下であることによりチューブから出しやすい適度な硬さとなるためである。 The content of the binder in the tooth surface cleaning composition is preferably 0.1% by mass or more and 1% by mass or less. This is because when the content is 0.1% by mass or more, the paste has a viscosity that makes it easy to pick up with a toothbrush, and when it is 1% by mass or less, it has an appropriate hardness that makes it easy to remove from the tube.
本発明に係る歯面清掃用組成物には、フッ化カルシウム以外のフッ素化合物を配合することができる。フッ素化合物を配合することにより、口腔内にフッ素イオンが供給され、さらなるう蝕予防効果が期待される。フッ化カルシウム以外のフッ素化合物としては、例えば、フッ化ナトリウム、フッ化カリウム、フッ化アンモニウム、フッ化第一スズ、モノフルオロリン酸ナトリウム、モノフルオロリン酸カリウム等が挙げられる。これらは単独でも２種以上配合してもよい。 The tooth surface cleaning composition according to the present invention may contain a fluorine compound other than calcium fluoride. By adding a fluorine compound, fluoride ions are supplied into the oral cavity, and further caries prevention effect is expected. Examples of fluorine compounds other than calcium fluoride include sodium fluoride, potassium fluoride, ammonium fluoride, stannous fluoride, sodium monofluorophosphate, and potassium monofluorophosphate. These may be used alone or in combination of two or more.
歯面清掃用組成物中のフッ化カルシウム以外のフッ素化合物の配合量は０．０２５質量％以上０．９質量％以下であることが好ましい。０．０２５質量％以上であることによりう蝕予防効果が期待でき、０．９質量％以下であることにより日常的に使用しても生体への影響がないためである。 The content of the fluorine compound other than calcium fluoride in the tooth surface cleaning composition is preferably 0.025% by mass or more and 0.9% by mass or less. This is because when the content is 0.025% by mass or more, a caries-preventing effect can be expected, and when the content is 0.9% by mass or less, daily use does not affect the living body.
本発明に係る歯面清掃用組成物には、防腐剤を配合することができる。防腐剤としては、例えば、エチルパラベン、メチルパラベン等が挙げられる。これらは単独でも２種以上配合してもよい。 The tooth surface cleaning composition according to the present invention may contain an antiseptic. Examples of antiseptics include ethylparaben and methylparaben. These may be used alone or in combination of two or more.
歯面清掃用組成物中の防腐剤の配合量は０．１質量％以上０．３質量％以下であることが好ましい。０．１質量％以上であることにより防腐効果が期待でき、０．３質量％以下であることにより日常的に使用しても生体への影響がないためである。 The content of the preservative in the tooth surface cleaning composition is preferably 0.1% by mass or more and 0.3% by mass or less. This is because when the content is 0.1% by mass or more, an antiseptic effect can be expected, and when the content is 0.3% by mass or less, there is no effect on the living body even in daily use.
本発明に係る歯面清掃用組成物には、液状成分が配合される。液状成分を配合することにより、溶媒として機能しペースト化することができる。また、湿潤剤としても機能する。液状成分としては、例えば、ポリエチレングリコール，エチレングリコール，プロピレングリコール，グリセリン，コンドロイチン硫酸またはその塩等，水等が挙げられる。これらは単独でも２種以上配合してもよい。 A liquid component is blended in the tooth surface cleaning composition according to the present invention. By blending the liquid component, it functions as a solvent and can be made into a paste. It also functions as a wetting agent. Examples of liquid components include polyethylene glycol, ethylene glycol, propylene glycol, glycerin, chondroitin sulfate or salts thereof, and water. These may be used alone or in combination of two or more.
歯面清掃用組成物中の液状成分の配合量は２０質量％以上５４質量％以下であることが好ましい。２０質量％以上であることにより柔らかいペースト状となり、５４質量％以下であることにより歯ブラシ等に載せる際に垂れにくくなるためである。より好ましくは、３０質量％以上４５質量％以下である。 The content of the liquid component in the tooth surface cleaning composition is preferably 20% by mass or more and 54% by mass or less. This is because when it is 20% by mass or more, it becomes a soft paste, and when it is 54% by mass or less, it becomes difficult to drip when placed on a toothbrush or the like. More preferably, it is 30% by mass or more and 45% by mass or less.
本発明に係る歯面清掃用組成物には、界面活性剤を配合することができる。界面活性剤を配合することにより、歯面清掃用組成物の洗浄効果や発泡効果を高めることができる。界面活性剤としては、例えば、ラウリル硫酸ナトリウム、ラウロイルサルコシン酸ナトリウム、ラウロイルメチルタウリン酸ナトリウム、ラウリルベタイン、セチル硫酸ナトリウム、ラウリルエーテル硫酸ナトリウム、ラウリルスルホコハク酸アンモニウム、ラウリル硫酸アンモニウム、ラウリルエーテル硫酸アンモニウム、ラウロイルイセチオン酸ナトリウム、ドデシルベンゼンスルホン酸ナトリウム、ドデシルベンゼンスルホン酸トリエタノールアミン、ココイルイセチオン酸ナトリウム等を挙げることができる。 The tooth surface cleaning composition according to the present invention may contain a surfactant. By blending a surfactant, the cleaning effect and foaming effect of the tooth surface cleaning composition can be enhanced. Examples of surfactants include sodium lauryl sulfate, sodium lauroyl sarcosinate, sodium lauroyl methyl taurate, lauryl betaine, sodium cetyl sulfate, sodium lauryl ether sulfate, ammonium lauryl sulfosuccinate, ammonium lauryl sulfate, ammonium lauryl ether sulfate, and lauroyl isethione. sodium acid, sodium dodecylbenzenesulfonate, triethanolamine dodecylbenzenesulfonate, sodium cocoylisethionate, and the like.
本発明に係る歯面清掃用組成物は、その粘度が２５℃において８０～４００Ｐａ・ｓであることが口腔内での使用に適しているため好ましい。より好ましくは、２５℃において１５０～２５０Ｐａ・ｓである。 The tooth surface cleaning composition according to the present invention preferably has a viscosity of 80 to 400 Pa·s at 25° C. because it is suitable for use in the oral cavity. More preferably, it is 150 to 250 Pa·s at 25°C.
本発明に係る歯面清掃用組成物には、粘度の調整のために増粘剤を配合することができる。増粘剤としては、例えば、無水ケイ酸、シリカゲル等のシリカ系化合物を挙げることができる。 The tooth surface cleaning composition according to the present invention may contain a thickening agent to adjust the viscosity. Examples of thickeners include silica-based compounds such as silicic anhydride and silica gel.
本発明に係る歯面清掃用組成物は、そのｐＨが９以上１０以下であることが必要である。ｐＨが９未満である場合、歯面清掃能力が低くなり、ｐＨが１０を超えている場合、口腔内で使用する際の刺激が大きくなってしまうためである。 The tooth surface cleaning composition according to the present invention must have a pH of 9 or more and 10 or less. This is because if the pH is less than 9, the ability to clean the tooth surface will be low, and if the pH exceeds 10, irritation will increase when used in the oral cavity.
本発明に係る歯面清掃用組成物には、着色料，保存料，防カビ剤，香料等の添加剤を適宜配合することもできる。 Additives such as colorants, preservatives, antifungal agents, perfumes, etc. may be appropriately added to the tooth surface cleaning composition of the present invention.
以下、実施例を挙げて本発明を詳細に説明するが、本発明は以下の実施例に限定されるものではない。 EXAMPLES The present invention will be described in detail below with reference to examples, but the present invention is not limited to the following examples.
＜実施例１＞
表１に示すように、炭酸カルシウム（メジアン径：１０μｍ）５３質量％，ソルビトール３質量％，カルボキシメチルセルロースナトリウム０．６質量％，ヒドロキシエチルセルロース０．８質量％，モノフルオロリン酸ナトリウム０．５質量％，メチルパラベン０．２質量％，無水ケイ酸０．４質量％，精製水２４．５質量％，グリセリン１６質量％，及び香料１質量％を配合し、混合機を用い混練してペースト状の歯面清掃用組成物を作製した。
<Example 1>
As shown in Table 1, calcium carbonate (median diameter: 10 μm) 53% by mass, sorbitol 3% by mass, carboxymethylcellulose sodium 0.6% by mass, hydroxyethylcellulose 0.8% by mass, sodium monofluorophosphate 0.5% by mass %, 0.2% by mass of methylparaben, 0.4% by mass of silicic anhydride, 24.5% by mass of purified water, 16% by mass of glycerin, and 1% by mass of perfume are blended and kneaded using a mixer to form a paste. A tooth surface cleaning composition was prepared.
＜実施例２～５及び比較例１～５＞
表１に示した組成にて、実施例１と同様の方法でペースト状の歯面清掃用組成物を作製した。
<Examples 2 to 5 and Comparative Examples 1 to 5>
Using the composition shown in Table 1, a paste-like tooth surface cleaning composition was prepared in the same manner as in Example 1.
［ｐＨ測定］
各歯面清掃用組成物について、ｐＨメーター（堀場製作所社 Ｄ－５２）を用いてｐＨを測定した。結果を表１に示す。
[pH measurement]
The pH of each tooth surface cleaning composition was measured using a pH meter (Horiba D-52). Table 1 shows the results.
［炭酸カルシウム又はフッ化カルシウム粒子のメジアン径］
レーザ回折／散乱式粒子径分布測定装置を使用して、炭酸カルシウム又はフッ化カルシウム粒子のメジアン径（体積基準）を測定した。
[Median diameter of calcium carbonate or calcium fluoride particles]
The median diameter (volume basis) of calcium carbonate or calcium fluoride particles was measured using a laser diffraction/scattering particle size distribution analyzer.
［歯面への侵襲性］
各歯面清掃用組成物の歯面への侵襲性を評価するため次の試験を行った。
牛歯エナメル質表面を耐水ペーパー＃４０００、及びダイヤモンドペースト３μ・１μとバフを用いて鏡面研磨し試験片とした。
次いで、試験片の研磨表面に対し、各歯面清掃用組成物を０．１ｇ使用し、歯面清掃用ラバーカップ（ジーシー社 ＰＴＣカップII）を用いて、１９４０ｒｐｍ、１分間の条件で歯面清掃を行った。
歯面清掃した部位について、レーザーマイクロスコープ（キーエンス社 ＶＫ－Ｘ２００）を用いて算術表面粗さ（Ｒａ）を測定した。
歯面への侵襲性の評価指標は下記のとおりである。結果を表１に示す。
非常に良い Ｒａが０．１０μｍ未満
良い Ｒａが０．１０μｍ以上０．１５μｍ未満
悪い Ｒａが０．１５μｍ以上
[Invasiveness to the tooth surface]
The following test was conducted to evaluate the invasiveness of each tooth surface cleaning composition to the tooth surface.
The bovine tooth enamel surface was mirror-polished using #4000 water-resistant paper, 3 μm and 1 μm diamond paste, and a buff to obtain a test piece.
Then, 0.1 g of each tooth surface cleaning composition was applied to the polished surface of the test piece, and a tooth surface cleaning rubber cup (GC PTC Cup II) was used to clean the tooth surface at 1940 rpm for 1 minute. cleaned up.
Arithmetic surface roughness (Ra) of the cleaned tooth surface was measured using a laser microscope (Keyence VK-X200).
The evaluation indices for invasiveness to the tooth surface are as follows. Table 1 shows the results.
Very good Ra is less than 0.10 μm Good Ra is 0.10 μm or more and less than 0.15 μm Poor Ra is 0.15 μm or more
［歯面清掃能力］
各歯面清掃用組成物の歯面清掃能力を評価するため次の試験を行った。
牛歯エナメル質表面を耐水ペーパー＃４０００で研磨した後、タンニン酸鉄を主成分とした着色液に１０分間浸漬しステインを沈着させ試験片とした。この試験片の色を分光測色計（コニカミノルタ社 ＣＭ－７００ｄ）を用いて測定した。
次いで、試験片に対し、各歯面清掃用組成物を０．１ｇ使用し、歯面清掃用ＰＴＣブラシを用いて、１９４０ｒｐｍ、３０秒間の条件で歯面清掃を行った。
歯面清掃した部位について、分光測色計を用いて色を測定し、歯面清掃前後のＬ*ａ*ｂ*色空間における色差ΔＥ*ａｂを算出した。
歯面清掃能力の評価指標は下記のとおりである。結果を表１に示す。
非常に良い ΔＥ*ａｂが１０以上
良い ΔＥ*ａｂが５以上１０未満
悪い ΔＥ*ａｂが５未満
[Tooth surface cleaning ability]
The following test was conducted to evaluate the tooth surface cleaning ability of each tooth surface cleaning composition.
After the bovine tooth enamel surface was polished with waterproof paper #4000, it was immersed in a coloring solution containing iron tannate as a main component for 10 minutes to deposit stain and prepare a test piece. The color of this test piece was measured using a spectrophotometer (Konica Minolta CM-700d).
Next, 0.1 g of each tooth surface cleaning composition was used for the test piece, and tooth surface cleaning was performed using a tooth surface cleaning PTC brush under conditions of 1940 rpm for 30 seconds.
The color of the cleaned tooth surface was measured using a spectrophotometer, and the color difference ΔE * ab in the L * a * b * color space before and after cleaning the tooth surface was calculated.
The evaluation index of the tooth surface cleaning ability is as follows. Table 1 shows the results.
Very good ΔE * ab is 10 or more Good ΔE * ab is 5 or more and less than 10 Poor ΔE * ab is less than 5
表１より、本発明に係る歯面清掃用組成物は、歯面への侵襲性が低く、且つ歯面清掃能力が高いことを確認することができる。 From Table 1, it can be confirmed that the tooth surface cleaning composition according to the present invention has low invasiveness to the tooth surface and high tooth surface cleaning ability.
Claims (1)
前記カルシウム化合物は、炭酸カルシウム及び／又はフッ化カルシウムであり、
前記カルシウム化合物の含有量が４９質量％以上６１質量％以下であり、
前記液状成分は、ポリエチレングリコール、エチレングリコール、プロピレングリコール、グリセリン、コンドロイチン硫酸及びその塩、並びに水の１種以上からなり、
前記液状成分の含有量が３４．１質量％以上であり、且つ
ｐＨが９以上１０以下であることを特徴とする歯面清掃用組成物。 A calcium compound having a median diameter of 5 μm or more and 24 μm or less and a liquid component,
The calcium compound is calcium carbonate and/or calcium fluoride,
The content of the calcium compound is 49% by mass or more and 61% by mass or less,
The liquid component consists of one or more of polyethylene glycol, ethylene glycol, propylene glycol, glycerin, chondroitin sulfate and salts thereof, and water,
The content of the liquid component is 34.1% by mass or more, and
A tooth surface cleaning composition having a pH of 9 or more and 10 or less.
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| JP2017143546A JP7126811B2 (en) | 2017-07-25 | 2017-07-25 | Tooth cleaning composition |
| CN201810812006.7A CN109288696A (en) | 2017-07-25 | 2018-07-23 | Mixture is used in flank of tooth cleaning |
| CN202311044374.9A CN116919835A (en) | 2017-07-25 | 2018-07-23 | Tooth surface cleaning mixture |
| KR1020180086228A KR102108005B1 (en) | 2017-07-25 | 2018-07-24 | Composition for dental cleaning |
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| JP (1) | JP7126811B2 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS582921B2 (en) * | 1973-03-20 | 1983-01-19 | ライオン株式会社 | toothpaste |
| GB1599689A (en) * | 1978-05-25 | 1981-10-07 | Colgate Palmolive Co | Dental cream composition |
| JPS60146814A (en) * | 1983-12-29 | 1985-08-02 | Lion Corp | Tooth paste composition |
| CN1988876B (en) * | 2004-07-06 | 2010-11-24 | 狮王株式会社 | Dentifrice composition |
| KR101490782B1 (en) * | 2008-10-14 | 2015-02-09 | 주식회사 엘지생활건강 | Toothpaste composition |
| JP2013163656A (en) | 2012-02-10 | 2013-08-22 | Gc Corp | Dentifrice |
| WO2014100928A1 (en) * | 2012-12-24 | 2014-07-03 | Colgate-Palmolive Company | Oral care composition |
| MX364736B (en) * | 2014-07-10 | 2019-05-03 | Procter & Gamble | Anti-calculus oral compositions. |
| JP6451562B2 (en) * | 2015-09-07 | 2019-01-16 | ライオン株式会社 | Oral composition |
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| KR20190011696A (en) | 2019-02-07 |
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