CN109276594A - A kind of Chinese medicine composition and preparation method thereof for treating herpes zoster - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating herpes zoster Download PDFInfo
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- CN109276594A CN109276594A CN201811210550.0A CN201811210550A CN109276594A CN 109276594 A CN109276594 A CN 109276594A CN 201811210550 A CN201811210550 A CN 201811210550A CN 109276594 A CN109276594 A CN 109276594A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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Abstract
The present invention relates to a kind of Chinese medicine compositions and preparation method thereof for treating herpes zoster.The Chinese medicine composition is composed of the following components: Semen Strychni 8-15g, borneol 27-35g, scorpio 27-35g, vinegar 500mL.Provided by the present invention for treating the Chinese medicine composition of herpes zoster, Semen Strychni is monarch drug in a prescription in side, and borneol is ministerial drug, has clearing heat and detoxicating, eliminating stasis to subdue swelling, treatment sore carbuncle and other effects, shares with vomiting nut, can increase the function of detoxicating and resolving a mass, swelling and pain relieving；Scorpio is adjutant, has relieve the wind syndrome antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation, sore scrofula and other effects, plays the role of assisting vomiting nut, borneol, can enhance clearing heat and detoxicating, the effect of removing obstruction in channels to relieve pain；Light-coloured vinegar is to make medicine, can weaken the toxicity of vomiting nut, have effects that the scattered stasis of blood, clearing damp, removing toxic substances, coordinating the drug actions of a prescription；All medicines share, has clearing heat and detoxicating, removes obstruction in channels to relieve pain, significant to the therapeutic effect of herpes zoster the effect of dispersing swelling and dissipating binds.
Description
Technical field
The invention belongs to the external preparation fields for treating herpes zoster (shingles zoster), and in particular to one kind is for treating
Chinese medicine composition of herpes zoster and preparation method thereof.
Background technique
Herpes zoster is also referred to as herpes zostor, is equivalent to the scope of modern medicine shingles zoster.When morbidity, cluster blister is along body
Side is arranged in zonal distribution, just like snakelike and sharp ache, sends out, therefore named herpes zostor because of its more skirt-roof.Modern medicine is ground
Study carefully and shows that herpes zoster is the skin bleb as caused by varicellazoster virus and ramitis.After this virus of primary infection not
It is certain to fall ill at once, in cell entry cutaneous nerve tip, hidden in the gangliocyte of spinal nerve or cranial nerve for a long time, when
When body is by risk factors such as wound, infection, overwork, then it is activated and causes to be generated inflammation by the neuromere and skin for invading position
And cause pain.Bleb has a dry, wet difference, reddish yellow it is different, all such as innumerable beading shape, it is red red to do person's color, shaped like cloud sheet, above blows
Grain makees pain fever.Wet person's color is yellowish-white, and blister differs in size, and pokes flowing water, table such as snake string.
Herpes zoster is more common in season in spring and autumn, and since feelings will is hurt, Liver Channel stagnated fire is malicious when feeling burning hot again, is dissolved in few sun, yin of fainting
Channels and collaterals smoke bright skin, train of thought；Or eating and drinking without temperance, noisy taste cause the spleen channel retention of damp-heat in the interior, it is evil when feeling burning hot again, visitor is bright in sun,
Lunar channels and collaterals, contamination skin, train of thought can be sent out as this disease.This disease with the passing of time burning hot wet poison in skin lesion surface is leaked, and bleb subsides,
But remaining heresy retention in the meridians and collaterals, so that qi deficiency to blood stasis, blockage of channel is obstructed, and local pain is more than.
Currently, the method for the treatment of herpes zoster is more both at home and abroad, the common drug of western medical treatment method has vitamin B1, vitamin
B12, idoxuridine etc., the common drug of Chinese traditional treatment method have Liushen Pills etc..Therapeutic effect of the existing herpes zoster drug to herpes zoster
It is easy to appear repeatedly, treatment cycle is longer, and whole curative effect needs to be further increased.
Summary of the invention
The purpose of the present invention is to provide a kind of for treating the Chinese medicine composition of herpes zoster, to solve existing herpes zoster medicine
The poor problem of the curative effect of object.
Second object of the present invention is to provide the preparation method of above-mentioned Chinese medicine composition, to solve existing herpes zoster medicine
The poor problem of the curative effect of object.
To achieve the above object, the technical solution of the Chinese medicine composition for treating herpes zoster of the invention is:
It is a kind of for treating the Chinese medicine composition of herpes zoster, it is composed of the following components: Semen Strychni 8-15g, borneol 27-
35g, scorpio 27-35g, vinegar 500mL.
The effect of primary raw material medicine, is briefly described below.
Semen Strychni is the seed of Loganiaceae Poisonnut plant Strychnos nux-vomica, and property is bitter, trembles with fear, big poison.Return liver, the spleen channel.Vomiting nut
2-5% containing alkaloid, mainly brucine (strychnine) and strychnia cure mainly rheumatic arthralgia, numbness, limbs paralysis
Paralysis, traumatic injury, skin sore, sore throat, toothache etc., the modern pharmacology proves that, vomiting nut has nervous system, cardiovascular system
There is adjustment effect, also has the effects that anti-inflammatory, antitumor, analgesia, antibechic, eliminating the phlegm.
Borneol is the processed goods of Spore density Borneolum Syntheticum resin, or chemically synthesize for camphor, turpentine oil etc.
Be processed into product, property is pungent, bitter, cool.Borneol contains a variety of ter penoids such as borneol, oleanolic acid, alphitolic acid, all with leading to
Key dissipates stagnated fire, removes screen improving eyesight, swelling and pain relieving and other effects.
Scorpio is the entirety of Buthidae Buthus animal buthus martensii Karscs, and property is salty, pungent, is put down, toxic, return liver warp.Scorpio is containing more
The effect of kind scorpion toxin, amino acid and inorganic elements, have relieving convulsion and spasm, remove obstruction in channels to relieve pain, dispersing pathogen accumulation, modern pharmacology card
Bright, scorpio Central nervous system and cardiovascular system have adjustment effect, also have analgesia, anti-epileptic, antithrombus formation etc.
Effect.
Provided by the present invention for treating the Chinese medicine composition of herpes zoster, Semen Strychni is monarch drug in a prescription in side, is stopped with dredging collateral
Bitterly, it is rapid that very fast and effect is absorbed the effect of detoxicating and resolving a mass, detumescence, treatment ulcer and malignant sore, after sharing with vinegar；Borneol is minister
Medicine has clearing heat and detoxicating, eliminating stasis to subdue swelling, treatment sore carbuncle and other effects, shares with vomiting nut, can increase detoxicating and resolving a mass, swelling and pain relieving
Function；Scorpio is adjutant, has relieve the wind syndrome antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation, sore scrofula and other effects, plays and assist Strychnos nux-vomica
The effect of son, borneol can enhance clearing heat and detoxicating, the effect of removing obstruction in channels to relieve pain；Light-coloured vinegar is to make medicine, can weaken the toxicity of vomiting nut, is had
There is the effect of scattered stasis of blood, clearing damp, removing toxic substances, coordinating the drug actions of a prescription.All medicines share, have it is clearing heat and detoxicating, remove obstruction in channels to relieve pain, the function of dispersing swelling and dissipating binds
Effect is significant to the therapeutic effect of herpes zoster.
For the dosage for further decreasing bulk pharmaceutical chemicals, improve fever, fire are burned, the therapeutic effect of the malaise symptoms such as pain, it is excellent
Choosing, it is above-mentioned for treating the Chinese medicine composition of herpes zoster, it is composed of the following components: Semen Strychni 10g, borneol 30g, scorpio
30g, vinegar 500mL.
The technical solution of the preparation method of Chinese medicine composition for treating herpes zoster of the invention is:
It is a kind of for treating the preparation method of the Chinese medicine composition of herpes zoster, comprising the following steps: by Semen Strychni, ice
Piece, scorpio pulverize it is last, be soaked in vinegar to get.
Provided by the present invention for treating the preparation method of the Chinese medicine composition of herpes zoster, preparation process is simple, utilizes leaching
Bubble process, which can facilitate, realizes that the raw materials the effective elements of the medicines such as Semen Strychni, borneol, scorpio extract, and the active constituent content of medical fluid is suitable
Preferably, skin absorbs excessive harmful components when can avoid wiping medical fluid, and then can realize fast on the basis of guaranteeing drug safety
Short stopping pain, incrustation are accelerated quickly to mitigate patient suffering, clinical efficacy is significant to the therapeutic process of herpes zoster.
To guarantee that medical fluid has more stable therapeutic effect, it is preferred that the time of the immersion is at least 2 days.
Specific embodiment
Embodiments of the present invention are described further combined with specific embodiments below.
The Chinese medicine composition embodiment 1 for being used to treat herpes zoster of the invention, composed of the following components: Semen Strychni 14g,
Borneol 34g, scorpio 28g, light-coloured vinegar 500mL.
The Chinese medicine composition embodiment 2 for being used to treat herpes zoster of the invention, composed of the following components: Semen Strychni 8g,
Borneol 27g, scorpio 32g, light-coloured vinegar 500mL.
The Chinese medicine composition embodiment 3 for being used to treat herpes zoster of the invention, composed of the following components: Semen Strychni 10g,
Borneol 30g, scorpio 30g, light-coloured vinegar 500mL.
The preparation method embodiment 1 of Chinese medicine composition for treating herpes zoster of the invention, prepares the Chinese medicine of embodiment 1
Composition, using following steps: by Semen Strychni (unhairing), borneol, scorpio pulverize it is last be put into light-coloured vinegar, seal, leaching
Bubble 3 days up to herpes zoster liniment.
The preparation method embodiment 2 of Chinese medicine composition for treating herpes zoster of the invention, prepares the Chinese medicine of embodiment 2
Composition, using following steps: by Semen Strychni (unhairing), borneol, scorpio pulverize it is last be put into light-coloured vinegar, seal, leaching
Bubble 2 days up to herpes zoster liniment.
The preparation method embodiment 3 of Chinese medicine composition for treating herpes zoster of the invention, prepares the Chinese medicine of embodiment 3
Composition, using following steps: by Semen Strychni (unhairing), borneol, scorpio pulverize it is last be put into light-coloured vinegar, seal, leaching
Bubble 5 days up to herpes zoster liniment.
Herpes zoster liniment obtained by above embodiments is externally applied drug, and sealing storage 2-3 does not influence drug effect.In application, first using
Alcohol sterilizes affected part, and the medical fluid shaken up is then applied to affected part with cotton swab, 2-3 times daily.Blister is forbidden to needle, skin ulceration
Serious person, which is used with caution, (to be sucked more Strychnos nux-vomica subconstiuents to avoid skin, leads to strychnism.)
The therapeutic effect of the herpes zoster liniment of embodiment 1-3, with 7 days as a course for the treatment of, specific criterion of therapeutical effect are investigated below
It is as follows:
Recovery from illness: steeping scab and fall off after 1-2 course for the treatment of of medication, skin restores intact, and pain disappears, without other uncomfortable senses
Feel.
It improves: steeping scab after 1-2 course for the treatment of of medication and largely fall off, pain disappears substantially, still there is uncomfortable feeling.
Effective: after 1-2 course for the treatment of of medication, blister largely forms a scab, pain relief but not up to expected effect.
Invalid: blister and pain have no apparent improvement after 1-2 course for the treatment of of medication.
For the small of the back fever, the severe herpes zoster patient that fire burns, pain etc. is uncomfortable, the therapeutic effect of embodiment 1-3 is such as
Shown in the following table 1.
The therapeutic effect of the herpes zoster liniment of 1 embodiment 1-3 of table
| Group | Case load | Recovery from illness | It improves | Effectively | In vain | Cure rate | Total effective rate |
| Embodiment 1 | 102 | 63 | 12 | 10 | 17 | 62% | 83% |
| Embodiment 2 | 98 | 68 | 14 | 12 | 4 | 69% | 96% |
| Embodiment 3 | 100 | 78 | 12 | 8 | 2 | 78% | 98% |
As shown in Table 1, the herpes zoster liniment of embodiment is higher to the cure rate and total effective rate of herpes zoster, all kinds of
Patient with severe symptoms is after the application externally applied liniment, and can be achieved substantially: coating 30-60min starts to relieve pain, and starts within 1-2 days to form a scab, 5-10
Its recovery from illness, clinical efficacy are significant.
The herpes zoster liniment of embodiment, from the cause of disease of herpes zoster, all medicines share, the poison for reducing each bulk pharmaceutical chemicals itself is secondary
The effect of effect, prominent its is clearing heat and detoxicating, remove obstruction in channels to relieve pain, dispersing swelling and dissipating binds, thus can effectively treat herpes zoster.
Typical case 1
Zhang, male, 58 years old, medical in October, 2013, patient was chief complaint with the small of the back cluster blister sharp ache one week.
The small of the back fever is consciously arrived before patient one week, fire burns, the discomforts such as pain, just occurs blister two days later, the pain increased, with arriving hospital
It is medical, it is diagnosed as shingles zoster (herpes zoster), gives antiviral, analgesic and symptomatic treatment effect are unobvious, go to a doctor, look into then
T.36.8 DEG C, BP.125/80mmHg, cardiopulmonary are normal, and liver and spleen is without enlargement.Symptoms include patient back and side of body rib portion cluster blister, along body
Body side is arranged in zonal distribution, just like snakelike, sharp ache unbearably, and is moaned talkative, and stool is dry, dark urine, red tongue body,
Yellow tongue fur, full and rapid pulse.Diagnosis: herpes zoster, treatment: it is clearing heat and detoxicating, it removes obstruction in channels to relieve pain, dispersing swelling and dissipating binds give the wiping of the embodiment of the present invention 2
Agent is applied to affected part, and patient's pain relief after a hour, blister starts to form a scab after one day, checks after a week, and patient is formed a scab all
It falls off, skin restores complete, and pain disappears, without other discomforts.
Typical case 2
Lee, female is 43 years old, medical in January, 2015, and patient is with more than 20 day of severity pain with chest side of body portion cluster blister
Main suit.20 days presensation pains in chest and hypochondrium of patient, fever, fire burn discomfort, just occur red dot after a few days, and blister, the pain increased immediately,
With going to see a doctor, it is diagnosed as herpes zoster (shingles zoster), gives antiviral, Chinese medicine Longdan Xiegan Tang number agent, outer liniment treatment
Effect is unobvious, goes to a doctor then, look into T.36.3 DEG C, BP.110/70mmHg, cardiopulmonary are normal, liver and spleen is without enlargement.Symptoms include patient's chest side of body
Waist and facial cluster blister, arrange in zonal distribution, just like it is snakelike, there are a small amount of blister ulceration, flowing water, blister expands around
It dissipates, area increases, and patient pain aches unbearably, cannot day and night rest, and agonizing, flushing rough, stool is dry, red urine, tongue nature
It is red, yellow and greasy fur.Diagnosis: herpes zoster, treatment: it is clearing heat and detoxicating, it removes obstruction in channels to relieve pain, dispersing swelling and dissipating binds give the liniment of the embodiment of the present invention 3
It is applied to affected part, patient's pain relief after 30 minutes, blister starts to form a scab two days later, checks after two weeks, and patient, which is formed a scab, all to fall off,
Skin restores complete, and pain disappears, without other discomforts.
Claims (4)
1. a kind of for treating the Chinese medicine composition of herpes zoster, which is characterized in that composed of the following components: Semen Strychni 8-15g,
Borneol 27-35g, scorpio 27-35g, vinegar 500mL.
2. as described in claim 1 for treating the Chinese medicine composition of herpes zoster, which is characterized in that composed of the following components:
Semen Strychni 10g, borneol 30g, scorpio 30g, vinegar 500mL.
3. a kind of as described in claim 1 for treating the preparation method of the Chinese medicine composition of herpes zoster, which is characterized in that packet
Include following steps: Semen Strychni, borneol, scorpio being pulverized last, be soaked in vinegar to get.
4. as claimed in claim 3 for treating the preparation method of the Chinese medicine composition of herpes zoster, which is characterized in that the leaching
The time of bubble is at least 2 days.
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| CN201811210550.0A CN109276594A (en) | 2018-10-17 | 2018-10-17 | A kind of Chinese medicine composition and preparation method thereof for treating herpes zoster |
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| CN201811210550.0A CN109276594A (en) | 2018-10-17 | 2018-10-17 | A kind of Chinese medicine composition and preparation method thereof for treating herpes zoster |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110585311A (en) * | 2019-10-17 | 2019-12-20 | 覃友云 | Chinese herbal medicine spray for treating herpes zoster |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1830865A2 (en) * | 2004-11-17 | 2007-09-12 | Kuki Gallmann | Topical treatment compositions |
| CN103263451A (en) * | 2013-06-05 | 2013-08-28 | 高原 | Traditional Chinese medicine for mainly treating trauma as well as sore and ulcer, preparation method and application of traditional Chinese medicine |
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2018
- 2018-10-17 CN CN201811210550.0A patent/CN109276594A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1830865A2 (en) * | 2004-11-17 | 2007-09-12 | Kuki Gallmann | Topical treatment compositions |
| CN103263451A (en) * | 2013-06-05 | 2013-08-28 | 高原 | Traditional Chinese medicine for mainly treating trauma as well as sore and ulcer, preparation method and application of traditional Chinese medicine |
Non-Patent Citations (1)
| Title |
|---|
| 胡郁坤 等: "《中医单方全书》", 30 June 2012, 湖南科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110585311A (en) * | 2019-10-17 | 2019-12-20 | 覃友云 | Chinese herbal medicine spray for treating herpes zoster |
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