CN109222082A - A kind of Chinese medicine composition is preparing the purposes in antifatigue food or health care product - Google Patents
A kind of Chinese medicine composition is preparing the purposes in antifatigue food or health care product Download PDFInfo
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- CN109222082A CN109222082A CN201811225158.3A CN201811225158A CN109222082A CN 109222082 A CN109222082 A CN 109222082A CN 201811225158 A CN201811225158 A CN 201811225158A CN 109222082 A CN109222082 A CN 109222082A
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- 230000002929 anti-fatigue Effects 0.000 title claims abstract description 41
- 239000003814 drug Substances 0.000 title claims abstract description 35
- 239000000203 mixture Substances 0.000 title claims abstract description 32
- 230000036541 health Effects 0.000 title claims abstract description 16
- 235000013305 food Nutrition 0.000 title claims abstract description 13
- 210000004369 blood Anatomy 0.000 claims abstract description 22
- 239000008280 blood Substances 0.000 claims abstract description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 229920002527 Glycogen Polymers 0.000 claims abstract description 17
- 229940096919 glycogen Drugs 0.000 claims abstract description 17
- 102100026189 Beta-galactosidase Human genes 0.000 claims abstract description 15
- 108010059881 Lactase Proteins 0.000 claims abstract description 15
- 239000002253 acid Substances 0.000 claims abstract description 15
- 108010005774 beta-Galactosidase Proteins 0.000 claims abstract description 15
- 230000002440 hepatic effect Effects 0.000 claims abstract description 15
- 229940116108 lactase Drugs 0.000 claims abstract description 15
- 210000002966 serum Anatomy 0.000 claims abstract description 15
- 241001264174 Cordyceps militaris Species 0.000 claims abstract description 14
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- RJGDLRCDCYRQOQ-UHFFFAOYSA-N anthrone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 RJGDLRCDCYRQOQ-UHFFFAOYSA-N 0.000 description 2
- 235000015197 apple juice Nutrition 0.000 description 2
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- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
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- 241001465754 Metazoa Species 0.000 description 1
- 241001248610 Ophiocordyceps sinensis Species 0.000 description 1
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- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 description 1
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 description 1
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- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
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- 229960003080 taurine Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention belongs to application in TCM fields, the purposes in antifatigue food or health care product is being prepared more particularly to a kind of Chinese medicine composition, the Chinese medicine composition comprises the following components in percentage by weight: sweetener 3%-9%, Cordyceps militaris 0.01%-0.04%, arillus longan 0.01%-0.03%, jujube 0.01%-0.03%, fructus lycii 0.01%-0.02%, rhizoma polygonati 0.01%-0.02%, Radix Glycyrrhizae 0.005%-0.015%, surplus are water.Chinese medicine composition provided by the invention can significantly reduce serum urea nitrogen level after movement, reduce the content of blood lactase acid and increase the deposit of hepatic glycogen, to which organism fatigue be effectively relieved, enhance body energy, has some improvement to the sub-health state tool of modern.
Description
Technical field
The invention belongs to application in TCM fields, and in particular to a kind of Chinese medicine composition is preparing antifatigue food or health care product
In purposes.
Background technique
Social now, work, rhythm of life are constantly accelerated, and increasingly competitive, people's lives have been filled with tired out
And pressure, gradually accumulation causes the inferior health problems such as confirmed fatigue, makes an antifatigue hot spot as physical-fitness medicine research.But
Current anti-fatigue beverage mainly based on caffeine, taurine and other functional ingredient, really can be improved in a short time muscle in anaerobic and
Endurance under aerobic conditions extends the duration of most high speed movement, refreshes the mind, but it is unsuitable for children, pregnant woman, painstaking effort
The crowds such as pipe Disease use, and long-term or largely drink the burden for be easy to causeing kidney, liver and nervous system function,
Influence the metabolism of human normal.In addition, although current Anti-fatigue drink color good taste, mostly use addition fragrant
The food additives such as essence, pigment, preservative are modulated, and largely drink also the running that will affect body items function for a long time.Cause
This, researcher gradually begins one's study using natural plants as raw material, the plant beverage with antifatigue effect.
Cordyceps militaris, also known as northern Chinese caterpillar Fungus, Eumycota, Ascomycetes, Hypocreales, Clavicipitaceae, Cordyceps.It is main
It is grown in the northern area in China.Cordceps militaris not only protein rich in and 18 kinds of amino acid, but also contain more than 30 kinds of people
Microelement needed for body is first-class excellent tonic product.Chinese medicine thinks, it can tonifying lung yin and kidney-replenishing, cure mainly kidney deficiency,
Impotence and seminal emission, soreness of waist and knee joint, eak after being ill, chronic cough are weak, phthisical cough phlegm blood, spontaneous sweating etc., are that a kind of can balance, adjust simultaneously
The Chinese medicine of yin-yang.
Chinese patent application CN 107811173A discloses the preparation method for antifatigue plant beverage of refreshing oneself, the invention by
14-16 parts of concentrated apple juice, concentration mulberry juice 0.1-1 parts, 0.1-1 parts of fructus lycii underflow, 0.1-0.5 parts of concentrated lemon juice, coffee
It is 0.05-0.2 parts of powder, 0.01-0.05 parts of green tea powder, 0.1-0.3 parts of honeysuckle concentrate, 0.001-0.01 parts of ginseng pulverate, compound
0.001-0.01 parts of amino acid powder compositions.The invention passes through addition ground coffee, green tea powder, honeysuckle concentrate, ginseng pulverate, compound
Amino acid powder makes plant beverage have antifatigue effect of refreshing oneself, and dense by addition concentrated apple juice, concentration mulberry juice, fructus lycii
Slurry, concentrated lemon juice etc. obtain suitable mouthfeel and nutrition, and extend the shelf-life of drink, long time without deposit, but
Containing caffeine constituents, the crowds such as uncomfortable children, pregnant woman, cardiovascular patient are used.
Chinese patent CN 104997091B discloses a kind of Cordyceps militaris instant solid beverage, by the raw material of following parts by weight
It is made: fruiting bodies of cordyceps militaris 20-50, Sweet tea 10-15, jujube 10-20, Gorgon fruit 10-20,10-20 parts of fructus lycii, cyclodextrin 20~
30.The invention sufficiently excavates various effects of Cordyceps militaris, is aided with the complete function of effective component using fruiting bodies of cordyceps militaris as base stock
Imitate comprehensive Sweet tea, the jujube for invigorating the spleen of enriching blood, supplementing the kidney to control the nocturnal Gorgon fruit, control the fructus lycii of liver-kidney Yin deficiency, obtain mainly to constitution void
Weak person is effective, have both tonifying lung invigorating the spleen, supplementing the kidney to control the nocturnal, skin maintenance and cosmetic benefits effect dietotherapy health drink.Although the invention is to constitution void
Weak person is effective, has both tonifying lung invigorating the spleen, supplementing the kidney to control the nocturnal, skin maintenance and cosmetic benefits effect, but does not refer to the antifatigue effect of product, and prepares
Drink be granule, be not easy to drink at any time.
Therefore, it develops a kind of extremely urgent using natural plants as raw material, the plant beverage with antifatigue effect.
Summary of the invention
To solve shortcomings and deficiencies existing in the prior art, the present invention provides a kind of Chinese medicine compositions resist in preparation it is tired
Purposes in labor food or health care product, which uses pure plant medicinal material as raw material, auxiliary using Cordyceps militaris as primary raw material
With arillus longan, jujube, fructus lycii, rhizoma polygonati, a kind of life that can significantly reduce serum urea nitrogen content after movement, reduce blood lactase acid is prepared
At and increase the deposit of hepatic glycogen, it is easy to carry to alleviate the health beverages of organism fatigue, and preparation method is simple, because
And it is of great significance to the research and development of the health beverages with antifatigue effect.
In order to achieve the above object, the invention is realized by the following technical scheme:
A kind of Chinese medicine composition is preparing the purposes in antifatigue food or health care product, and the Chinese medicine composition is by following
The group of weight percent is grouped as: sweetener 3%-9%, Cordyceps militaris 0.01%-0.04%, arillus longan 0.01%-0.03%, greatly
Jujube 0.01%-0.03%, fructus lycii 0.01%-0.02%, rhizoma polygonati 0.01%-0.02%, Radix Glycyrrhizae 0.005%-0.015%, surplus
For water.
Preferably, the Chinese medicine composition comprises the following components in percentage by weight: sweetener 5%-9%, pupa worm
Careless 0.02%-0.04%, arillus longan 0.02%-0.03%, jujube 0.02%-0.03%, fructus lycii 0.01%-0.02%, rhizoma polygonati
0.01%-0.02%, Radix Glycyrrhizae 0.010%-0.015%, surplus are water.
Preferably, the Chinese medicine composition comprises the following components in percentage by weight: sweetener 7%, Cordyceps militaris
0.035%, arillus longan 0.02%, jujube 0.02%, fructus lycii 0.01%, rhizoma polygonati 0.01%, Radix Glycyrrhizae 0.010%, surplus is water.
Preferably, the Chinese medicine composition can reduce after movement serum urea nitrogen level in body.
Preferably, the Chinese medicine composition can reduce the generation of body blood lactase acid after movement.
Preferably, the Chinese medicine composition can increase the deposit of hepatic glycogen after movement.
Preferably, the Chinese medicine composition can be used for relieving fatigue symptom, enhance the vigor of body.
The Chinese medicine composition is using Cordyceps militaris as main component, because it contains cordycepin and Cordyceps sinensis polysaccharide, can promote new old
Metabolism improves immunity, is aided with the arillus longan of tonifying heart and spleen, the jujube of nourishing blood and tranquilization, the fructus lycii for supporting eyeball item and tonifying spleen profit
The rhizoma polygonati of lung, the deposit that serum urea nitrogen content after moving can be significantly reduced, the generation of blood lactase acid is reduced and increase hepatic glycogen, from
And organism fatigue is effectively relieved, the energy of body is improved, is had some improvement to the sub-health state tool of modern.
Compared with prior art, the invention has the following advantages: the Chinese medicine composition that preparation method of the present invention obtains
The deposit that serum urea nitrogen content after moving can be significantly reduced, the generation of blood lactase acid is reduced and increase hepatic glycogen, thus effectively slow
Organism fatigue is solved, the energy of body is improved.
Specific embodiment
Above content of the invention is described in further detail again below by way of specific embodiment.But this should not be managed
Solution is limited only to embodiment below for the range of the above-mentioned theme of the present invention.The case where not departing from above-mentioned technical idea of the invention
Under, the various replacements or change made according to ordinary skill knowledge and customary means, should all include in model of the invention
In enclosing.
Embodiment 1
A kind of preparation method of Anti-fatigue drink, comprising the following steps:
(1) take Cordyceps militaris 0.6kg, arillus longan 0.375kg, jujube 0.375kg, fructus lycii 0.225kg, rhizoma polygonati 0.225kg,
Radix Glycyrrhizae 0.18kg;After impregnating two hours, add 15L boiling to boil, keep slightly boiled 2h, obtain extracting solution, keep in, takes out filter residue;
(2) add 12L boiling to boil filter residue, keep slightly boiled 2h, obtain extracting solution, closed with extracting solution obtained in step (2)
After and, be cooled to 20 DEG C hereinafter, by coolant liquid butterfly centrifugal (4000-6000r/min), be concentrated into relative density be 15% with
On, concentrate is obtained, sterilizes 20-36s at 138 DEG C ± 2 DEG C, filling, filling fluid temperature≤25 DEG C.
(3) white granulated sugar 90kg is taken, 50% liquid glucose is dissolved in water into, takes inspissated juice 19kg, heating water dissolves it sufficiently
It is placed in blend tank with liquid glucose afterwards, water is added to deploy to 1 ton, it is filling with pop can, PET bottle or Tetra Pak, after the assay was approved
Finished product.
Experimental example 1
The preparation of animal subject, concrete operation step are as follows:
(1) given the test agent: taking 60 weight is the SPF grade male white mouse of 18~22g, is randomly divided into 5 groups, every group 12
Only, respectively negative control group, low dose group, middle dose group and high dose group, wherein negative control group is pure water, it is low, in,
High dose group is Anti-fatigue drink prepared by the present invention;
(2) dose design: the human body recommended daily dosage of Anti-fatigue drink and positive controls of the invention is 2 tanks/day, is pressed
It is 8.3333ml/kg BW that 60 kg body weight adults, which calculate recommended daily dosage,.If 1.2,2.5,33.9 times of 7.4ml/kg BW are anti-
Three dosage groups of tired drink concentrate, are equivalent to the Anti-fatigue drink of 41.7,83.3,250.0ml/kg BW, to recommend to take daily
5,10,30 times of amount, the specific dosage of each group is as shown in the table:
1 Anti-fatigue drink dose design of table
(3) prepared by tested material: 33.9 times of Anti-fatigue drink concentrates is measured daily, by 1.2,2.5,7.4ml pure water
It deploys to the ratio of 10.0ml and sample liquid is made, used respectively for low, middle and high dose groups, according to mouse weight adjustment sample configuration
Amount.
(4) medication: each group gives tested material, negative control every time by once a day with 0.1ml/10g BW stomach-filling
Group gives pure water by equivalent capability stomach-filling.
Experimental example 2
The swimming with a load attached to the body of mouse is tested, and specific experiment is shown in steps are as follows:
33.9 times of Anti-fatigue drink concentrates are given 30 days, after last gives tested material 30min, by root of the tail portion load 5%
The mouse of weight sheet lead is placed in the swimming trunk went swimming of depth of water 30cm, 25 ± 0.5 DEG C of water temperature, record mouse from swim till death
The time died, i.e. mice burden swimming time.
Experimental result is as shown in table 2:
Influence of 2 Anti-fatigue drink of table to the mice burden swimming time
Note: * indicates each dosage group P < 0.05 compared with negative control group;* indicates each dosage group compared with negative control group
P<0.01。
As shown in Table 2, the walking weight load of all dosage groups of the present invention is above negative control group, wherein middle dosage
The swimming time longest of group has significant statistical difference, and high dose group and negative control group compared with negative control group
Compared to statistical difference.Experimental result is positive, and it is negative to show that Anti-fatigue drink prepared by the present invention can significantly extend mouse
Weight swimming time, increases the activity of body.
Experimental example 3
The measurement experiment of mouse urea nitrogen, specific experiment is shown in steps are as follows:
Give 33.9 times of Anti-fatigue drink concentrates 30 days, after last gives tested material 30min, mouse of each group without weight bearing
Respectively in 30 DEG C of water went swimming 90min of water temperature, eyeball blood is adopted in rest after sixty minutes, and 4 DEG C of refrigerators separate serum after placing 3 hours,
With enzyme process kit measurement urea nitrogen.
Experimental result is as shown in table 3:
Influence of 3 Anti-fatigue drink of table to serum urea nitrogen content after mouse movement
Note: * indicates each dosage group P < 0.05 compared with negative control group;* indicates each dosage group compared with negative control group
P<0.01。
As shown in Table 3, the serum urea nitrogen level of each dosage group is significantly lower than negative control group, wherein middle dose group tool
There is significant statistical difference, high dose group has statistical difference.Experimental result is positive, shows prepared by the present invention antifatigue
Drink can significantly reduce after movement serum urea nitrogen level in body.
Experimental example 4
The measurement experiment of mouse Serum lactic acid content, specific experiment is shown in steps are as follows:
33.9 times of Anti-fatigue drink concentrates are given 30 days, after last gives tested material 30min, after adopting eyeball blood for the first time
30 DEG C of swimming 10min of water temperature are put in, adopt eyeball blood for the second time, then stops peace and quiet 20min, adopts eyeball blood for the third time, are used
LACTATE~PAP kit measures the lactic acid of swim preceding lactic acid and 0min, 20min after swimming respectively, when calculating three according to formula
Point lactic acid area under the curve.
Blood lactase acid area under the curve=5 × (blood lactase acid value+3 before swimming × blood lactase acid value+2 × swimming of 0min after swimming
The blood lactase acid value of rest 20min afterwards)
Experimental result is as shown in table 4, table 5:
Influence of 4 Anti-fatigue drink of table to the forward and backward Serum lactic acid content of mouse movement
Influence of 5 Anti-fatigue drink of table to blood lactase acid area under the curve before and after mouse movement
Note: * indicates that each dosage group P < 0.05 compared with negative control group, * * indicate each dosage group compared with negative control group
P<0.01。
By table 4 with table 5 it is found that the Serum lactic acid content of each dosage group is low compared with negative control group, blood lactase acid area under the curve with
Negative control group is more reduced, wherein the lactic acid content of middle dose group is minimum, has significant statistical difference, high
Dosage group has statistical difference.Experimental result is positive, then shows that Anti-fatigue drink product prepared by the present invention can obviously reduce
The generation of body blood lactase acid after movement, the symptom alleviating muscular fatigue, aching.
Experimental example 5
The measurement experiment of mouse hepatic glycogen, specific experiment is shown in steps are as follows:
Using anthrone method.After last gives tested material 30min, 50mg liver is accurately weighed, 4ml TCA liquid is added, every pipe is even
1min is starched, 15min is centrifuged with 3000r/min, takes supernatant 0.5ml, 95% ethyl alcohol 2ml is added, mixes well, 37 DEG C of water-baths
3h dissolves glycogen with 1ml distilled water, and after glycogen is completely dissolved each pipe is added in 5ml anthrone reagent by oscillation, immerses boiling water
15min uses THERMO multi-function microplate reader (wavelength 620nm) colorimetric estimation after cooling.Hepatic glycogen content is calculated by formula.
Experimental result is as shown in table 6:
Influence of 6 Anti-fatigue drink of table to the hepatic glycogen of mouse
Note: * indicates each dosage group P < 0.05 compared with negative control group;* indicates each dosage group compared with negative control group
P<0.01。
As seen from the above table, the hepatic glycogen storage capacity of each dosage group is obviously higher than negative control group, wherein middle dose group
Hepatic glycogen content highest has significant statistical difference, and low dose group then has statistical difference, the content of high dose group
It is more not as good as low dose group, show that dosage increases the deposit that can increase hepatic glycogen in a certain range, the excessively high effect instead of dosage is not
Greatly.Anti-fatigue drink prepared by the present invention can dramatically increase the content of hepatic glycogen, the intracorporal energy reserve of machine be improved, to improve
Body energy relieves fatigue symptom.
In conclusion according to " health food functional evaluation program and the method for inspection ", if swimming with a load attached to the body and two or two
Or more biochemical indicator (blood lactase acid, serum urinary nitrogen, hepatic glycogen) be the positive, that is, can determine that the tested material have alleviate physical strength
The function of fatigue.Now by above-mentioned experimental result it is found that Anti-fatigue drink prepared by the present invention can significantly extend the weight bearing of mouse
Swimming time reduces the generation of blood lactase acid, increases the serum of mouse hepatic glycogen after movement laid in and can reduce mouse after movement
The content of urea nitrogen.Therefore, Anti-fatigue drink prepared by the present invention has significant relaxation effect for the fatigue symptom of body,
There is facilitation to the recovery of function after movement, there is substantive distinguishing features outstanding and significant progress.
Above-described embodiment is merely exemplary to illustrate the principle of the present invention and its performance, is not construed as limitation of the present invention, this
The protection scope of invention should be defined by the scope defined by the claims..For those skilled in the art
Speech, all without departing from the spirit and scope of the present invention, carries out modifications and changes to above-described embodiment.Therefore, belonging to such as
All that there is notice Chang Shizhe to be completed in technical field without departing from the spirit and technical ideas disclosed in the present invention etc.
Modifications and changes are imitated, should be covered by the claims of the present invention.
Claims (7)
1. a kind of Chinese medicine composition is preparing the purposes in antifatigue food or health care product, which is characterized in that the Chinese medicine group
It closes object to comprise the following components in percentage by weight: sweetener 3%-9%, Cordyceps militaris 0.01%-0.04%, arillus longan
0.01%-0.03%, jujube 0.01%-0.03%, fructus lycii 0.01%-0.02%, rhizoma polygonati 0.01%-0.02%, Radix Glycyrrhizae
0.005%-0.015%, surplus are water.
2. a kind of Chinese medicine composition according to claim 1 is preparing the purposes in antifatigue food or health care product, special
Sign is that the Chinese medicine composition comprises the following components in percentage by weight: sweetener 5%-9%, Cordyceps militaris 0.02%-
0.04%, arillus longan 0.02%-0.03%, jujube 0.02%-0.03%, fructus lycii 0.01%-0.02%, rhizoma polygonati 0.01%-
0.02%, Radix Glycyrrhizae 0.010%-0.015%, surplus is water.
3. a kind of Chinese medicine composition according to claim 2 is preparing the purposes in antifatigue food or health care product, special
Sign is that the Chinese medicine composition comprises the following components in percentage by weight: sweetener 7%, Cordyceps militaris 0.035%, dragon
Eye meat 0.02%, jujube 0.02%, fructus lycii 0.01%, rhizoma polygonati 0.01%, Radix Glycyrrhizae 0.010%, surplus are water.
4. a kind of any Chinese medicine composition is preparing the use in antifatigue food or health care product according to claim 1~3
On the way, which is characterized in that the Chinese medicine composition can reduce after movement serum urea nitrogen level in body.
5. a kind of any Chinese medicine composition is preparing the use in antifatigue food or health care product according to claim 1~3
On the way, which is characterized in that the Chinese medicine composition can reduce the generation of body blood lactase acid after movement.
6. a kind of any Chinese medicine composition is preparing the use in antifatigue food or health care product according to claim 1~3
On the way, which is characterized in that the Chinese medicine composition can increase the deposit of hepatic glycogen after movement.
7. a kind of any Chinese medicine composition is preparing the use in antifatigue food or health care product according to claim 1~3
On the way, which is characterized in that the Chinese medicine composition can be used for relieving fatigue symptom, enhance the vigor of body.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105079447A (en) * | 2014-05-14 | 2015-11-25 | 成都百草和济科技有限公司 | Health care product or medicine composition capable of relieving fatigue and enhancing immunity |
CN105360824A (en) * | 2014-11-14 | 2016-03-02 | 广州王老吉药业股份有限公司 | Chinese caterpillar fungus beverage and preparation method thereof |
KR20180085624A (en) * | 2017-01-19 | 2018-07-27 | (주)없었던일로 | Health supplement foods using crucian carp |
-
2018
- 2018-10-20 CN CN201811225158.3A patent/CN109222082A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105079447A (en) * | 2014-05-14 | 2015-11-25 | 成都百草和济科技有限公司 | Health care product or medicine composition capable of relieving fatigue and enhancing immunity |
CN105360824A (en) * | 2014-11-14 | 2016-03-02 | 广州王老吉药业股份有限公司 | Chinese caterpillar fungus beverage and preparation method thereof |
KR20180085624A (en) * | 2017-01-19 | 2018-07-27 | (주)없었던일로 | Health supplement foods using crucian carp |
Non-Patent Citations (3)
Title |
---|
何来英等: "《抗疲劳饮食法》", 31 October 2008, 金盾出版社 * |
周秋丽等: "《现代中药基础研究与临床》", 30 June 2012, 天津科技翻译出版公司 * |
徐洁等: "《芳香植物研究与应用》", 31 October 2017, 云南科技出版社 * |
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