CN107951984A - Preparation method of kidney-tonifying yang-strengthening health wine - Google Patents
Preparation method of kidney-tonifying yang-strengthening health wine Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Abstract
The invention provides a preparation method of kidney-tonifying and yang-strengthening health wine, and belongs to the technical field of deep processing of traditional Chinese medicinal materials. Selecting 1-8 parts of medlar, 1-8 parts of semen cuscutae, 1-8 parts of schisandra chinensis, 1-8 parts of raspberry, 1-8 parts of semen plantaginis, 1-10 parts of epimedium, 1-10 parts of morinda officinalis, 1-4 parts of white paeony root, 1-4 parts of radix rehmanniae, 1-4 parts of golden cypress, 1-4 parts of rhizoma anemarrhenae and 1-2 parts of maca according to the parts by weight, crushing and sieving; sealing and fermenting the screened traditional Chinese medicinal materials with sucrose, yeast and water; filtering the fermentation liquid, taking the supernatant, repeatedly precipitating and filtering to obtain 12 kinds of medicinal fermentation stock solution; ageing the 12 kinds of filtered dregs and Xiaoqu liquor, and settling and filtering for multiple times to obtain 12 kinds of medicinal Xiaoqu liquor extract; mixing the fermentation stock solution and the leaching solution, adding a sweetening agent, sterilizing and filling to obtain the kidney-tonifying and yang-strengthening health wine. The wine is used as a carrier, the wine contains a plurality of medicinal materials, the medicinal materials have the effects of nourishing yin, tonifying yang, replenishing vital essence and tonifying kidney by virtue of the wine property and the wine efficacy, and the added allochthoma can resist depression and correct male psychogenic sexual dysfunction.
Description
Technical field
The invention belongs to Chinese medicine deep process technology field, is specially a kind of preparation method of tonifying kidney and strengthening yang health preserving wine.
Background technology
For Chinese health liquor enterprise in 2009 more than 5000, health liquor market comsupton scale in 2011 breaks through 13,000,000,000 yuan, and
Calculated according to expert, the actual capacity in China white wine market is about 350,000,000,000 yuan, and the market capacity that 13,000,000,000 yuan of health liquor is only white wine
The 3.7% of market capacity.In recent years, Spirits market profit margin glides, overall that decline trend is presented, and more Liquor-making Enterprises ＆s carry out
Industrial restructuring, health liquor become an important directions of transition, the strength wine, the Huang of five-Grain Liquor of Jing Brand Co., Ltd. then occur
The more the wine industry giants such as gin, the wine of Maotai, an abundant three penis wine march the situation in health liquor market one after another.Seem China
Health liquor has been enter into the stage of competition monopolization, and still, this several brand enterprises are still not enough to form trade monopoly, in data
Embodiment is exactly that the market share of this four or five famous brand name enterprises is not reaching to enough monopoly positions, has phase in each level
When rival exist.
Male sexual disfunction is a common disease, and incidence accounts for the 10% of adult male.Male's sexual is one
Extremely complex physiology course, is the knot to be acted synergistically by various aspects such as nervous and mental factors, endocrine function, sexual organs
Fruit, wherein leading role are corticocerebral property conditioned reflex.Many factors can cause male sexual disfunction, clinically
Male sexual disfunction is generally divided into two major class of feature sex dysfunction and organic sex dysfunction, wherein most of patients
For feature sex dysfunction.Male sexual disfunction mainly show erectile dysfunction (erectile dysfunction,
ED) ED and defective ejaculation, the latter include premature ejaculation, do not ejaculate, retrograde ejaculation.Traditional Chinese medicine thinks, sex dysfunction mainly with " kidney "
Have a relation, and Chinese medicine treatment can integrally-regulated body function, tonifying kidney and strengthening yang, corrects the exception of renal function, for male's property
Dysfunction has good therapeutic effect.
It is another studies have reported that, although ED is probably since the histoorgan lesion such as blood vessel, psychoneural and endocrine is drawn
Hair, but psychologic factors are carried throughout.Even psychogenic ED, the somatization of spirit change can also be further resulted in
Change, form the change of some physiological functions of histoorgan, and form vicious circle.Long-term ED can make to become on patients ' psychological
It is fragile, depressed, and depressed and anxiety is the generally acknowledged ED causes of disease.Depressive emotion can inherently cause ED, ED to aggravate depressed feelings again
Thread, and the depressive emotion for improving patient will be helpful to the rehabilitation of sexual function.
The content of the invention
It is an object of the invention to provide a kind of preparation side of tonifying kidney and strengthening yang health preserving wine for existing male sexual disfunction
Zymotechnique is combined by method, preparation method of the present invention with traditional immersion, develops " light side " new health wine.This
Goal of the invention is achieved through the following technical solutions：
A kind of preparation method of tonifying kidney and strengthening yang health preserving wine, comprises the following steps：
1) Chinese medicine pre-processes：Fruit of Chinese wolfberry 1-8 parts selected by weight, 1-8 parts of Semen Cuscutae, 1-8 parts of Schisandra chinensis, raspberry
1-8 parts, 1-8 parts of plantain seed, 1-10 parts of Herba Epimedii, 1-10 parts of Morinda officinalis, 1-4 parts of Radix Paeoniae Alba, 1-4 parts of the dried rhizome of rehmannia, 1-4 parts of Cortex Phellodendri, know
Female 1-4 parts and 1-4 parts of maca, crush, sieving；
2) ferment：The above-mentioned Chinese medicine after pulverizing and sieving is loaded into fermentation tank together with sucrose, saccharomycete, water, then
It is sealed by fermentation, is fermentation termination when zymotic fluid alcoholic strength rises to 8-17 degree；
3) filter：By above-mentioned filtering fermentation liquor, taking supernatant, supernatant is filtered to precipitation is not produced repeatedly, obtains 12 taste medicines hair
Ferment stoste；
4) ageing is extracted：The 12 taste dregs of a decoction that step 3) is obtained by filtration with after Xiaoqu wine ageing 60-90 days, multiple supernatant mistake
Filter obtains 12 taste medicine Xiaoqu wine leaching liquors；
5) mix, season：12 taste medicine fermenation raw liquids and 12 taste medicine Xiaoqu wine leaching liquors are mixed, so as to get mixing medicinal liquor
The number of degrees are 20-45 degree, and add sweetener seasoning；
6) sterilizing, tinning：Seasoned medicinal liquor sterile filling after pasteurization will be mixed and obtain tonifying kidney and strengthening yang health
Wine.
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 1),
Described fruit of Chinese wolfberry 1-4 parts, 1-4 parts of Semen Cuscutae, 1-4 parts of Schisandra chinensis, 1-4 parts of raspberry, 1-4 parts of plantain seed, 2-4 parts of Herba Epimedii,
1-2 parts of 2-4 parts of Morinda officinalis, 1-2 parts of Radix Paeoniae Alba, 1-2 parts of the dried rhizome of rehmannia, 1-2 parts of Cortex Phellodendri, 1-2 parts of rhizoma anemarrhenae and maca.
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 1),
The sieving is 30-50 mesh sieves.
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 2),
The sucrose is 1-4 parts, and the saccharomycete is 1-4 parts, and water is 20-50 parts；1-4 weeks before the sealing and fermenting, hair is opened daily
The exhausting-gas hole exhaust of ferment bucket.
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 3),
It is described to be filtered into 30-50 mesh sieves.
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 4),
The number of degrees of the 12 taste medicine Xiaoqu wine leaching liquor are 55-65 degree.
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 5),
12 taste medicine fermenation raw liquids are 2-8 parts in the mixing medicinal liquor and 12 taste medicine Xiaoqu wine leaching liquors are 1-5 parts.
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 5),
The sweetener is oligoisomaltose and honey, and the addition of oligoisomaltose is 1-6 parts, and the addition of honey is 1-
6 parts,
As an a kind of specific embodiment of the preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention, in step 6),
The temperature of the pasteurization is 65-75 DEG C.
The present invention also provides a kind of tonifying kidney and strengthening yang health preserving wine, it is prepared using above-mentioned preparation method.
Compared with prior art, the invention has the advantages that：
For the present invention using wine as carrier, medicinal material containing multi-flavor in wine, medicine borrows alcoholic strength, and wine helps the efficacy of a drug, there is nourishing and strengthening Yin and Yang, strengthening the essence kidney tonifying
The effect of, the maca added in tonifying kidney and strengthening yang health preserving wine of the present invention can improve the depressive mood of people, correct male's psychogenic
Sex dysfunction, and other taste medicines integrally nurse one's health body and local kidney channel nourishes, it is strong that both combinations compensate for tradition
The deficiency that positive wine list one nourishes, and evaded bad anti-by being brought during chemicals correction depression the treatment of sexual dysfunction
Should.
Traditional kidney-invigorating Yang strengthening wine is white wine+medicinal material " double recipe " soaking wine, and dense flavour of a drug are presented, and preparation method of the present invention is adopted
It is combined with zymotechnique and traditional immersion, develops " light side " new health wine.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
A kind of preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention is explained in detail with reference to specific preparation process
Explanation.
A kind of preparation method of tonifying kidney and strengthening yang health preserving wine, comprises the following steps：
1) Chinese medicine pre-processes
Fruit of Chinese wolfberry 1-8 parts selected by weight, 1-8 parts of Semen Cuscutae, 1-8 parts of Schisandra chinensis, 1-8 parts of raspberry, plantain seed 1-8
Part, 1-10 parts of Herba Epimedii, 1-10 parts of Morinda officinalis, 1-4 parts of Radix Paeoniae Alba, 1-4 parts of the dried rhizome of rehmannia, 1-4 parts of Cortex Phellodendri, 1-4 parts of rhizoma anemarrhenae and maca 1-4
Part, crush, sieving.
Further, 12 taste medicines are preferably 1-4 parts of the fruit of Chinese wolfberry, Semen Cuscutae 1-4 by weight in pretreatment with Chinese medicine step
Part, 1-4 parts of Schisandra chinensis, 1-4 parts of raspberry, 1-4 parts of plantain seed, 2-4 parts of Herba Epimedii, 2-4 parts of Morinda officinalis, 1-2 parts of Radix Paeoniae Alba, the dried rhizome of rehmannia
1-2 parts of 1-2 parts, 1-2 parts of Cortex Phellodendri, 1-2 parts of rhizoma anemarrhenae and maca.
Tonifying kidney and strengthening yang health preserving wine of the present invention adopts 12 taste Chinese medicines：It is the fruit of Chinese wolfberry, Semen Cuscutae, Schisandra chinensis, raspberry, plantain seed, excessive
The sheep leaves of pulse plants, Morinda officinalis, Radix Paeoniae Alba, the dried rhizome of rehmannia, Cortex Phellodendri, rhizoma anemarrhenae and maca.Wherein, the fruit of Chinese wolfberry, Semen Cuscutae, Schisandra chinensis are nourishing liver and kidney, enrich blood
Strengthening the essence；Raspberry kidney-nourishing mends essence；The sensible Li Shui of plantain seed, this five kinds of Chinese medicines cure mainly deficiency of kidney essence, long infertility, and the soreness of waist is passed out semen,
Impotence and premature ejaculation, dribbling urination is unclear to wait disease.Herba Epimedii, it is warm-natured do not tremble with fear, can strengthening the essence gas, insufficiency of kidney-YANG person preferably it；Morinda officinalis can be mended
Kidney and enhancing body, is the supporing yang product of strong kidney available for treatment both kidney deficiency kidney impotences, Herba Epimedii, Morinda officinalis, and five kinds of Chinese medicine cooperative compensatings,
Can be spiritual plentifully.Radix Paeoniae Alba has effects that nourishing blood and liver, slow middle analgesic, holds back cloudy receipts sweat, has for spontaneous sweating, fever due to yin deficiency
Good therapeutic effect.The dried rhizome of rehmannia, Cortex Phellodendri, rhizoma anemarrhenae nourishing Yin and clearing heat, mediation property of medicine.And maca originates in 3500-4500 meters of height above sea level
South America andes region, the Puno ecotope being mainly distributed in Peru and Peru the southeastern city of Puno, are Cruciferae
(Cruciferae) Lepidium (Lepidium) plant, maca can improve anxiety and depression, reduce post menopausal to conspicuousness
The diastolic pressure and improvement symptoms of depression of women.
The maca added in tonifying kidney and strengthening yang health preserving wine of the present invention, can improve the depressive mood of people, and other 11 taste medicines
Body is integrally nursed one's health again and local kidney channel nourishes, both combinations are that compensate for the deficiency of the single nourishing of traditional liquor for strengthening Yang, again
The adverse reaction brought when correcting depressed the treatment of sexual dysfunction by chemicals is evaded.
The sieving is 30-50 mesh sieves, is more preferably 40 mesh sieves.
2) ferment
The above-mentioned Chinese medicine after pulverizing and sieving is loaded into fermentation tank together with sucrose, saccharomycete, water, then sealing hair
Ferment, is fermentation termination when zymotic fluid alcoholic strength rises to 8-17 degree.
Further, the sucrose is 1-4 parts, and the saccharomycete is 1-4 parts, and water is 20-50 parts.Sucrose adds can be to medicine
The bitter taste of material is neutralized, and improves the mouthfeel of zymotic fluid.The addition of saccharomycete can accelerate the fermentation of zymotic fluid, shorten fermentation
Time.
Further, the saccharomycete is preferably wine yeast.Wine yeast relative to other yeast, imitate by its fermentation
Fruit is preferable, can effectively shorten the reaction time, can improve the alcoholic strength of zymotic fluid, decrease or soft Chinese medicine in a short time
Bitter taste, and tart flavour and flavour of a drug are moderate, and do not lose active ingredient.
Further, 1-4 weeks before the sealing and fermenting, the exhausting-gas hole exhaust of fermenter is opened daily, and is sealed by fermentation temperature
For 15-28 DEG C.During saccharomycetes to make fermentation, gas can be produced, can rise bottle, so to open small row daily within 1-4 weeks before being sealed by fermentation
Stomata is deflated, but will not pollute fermentation system.
3) filter
By above-mentioned filtering fermentation liquor, taking supernatant, supernatant is filtered to precipitation is not produced repeatedly, obtains 12 taste medicine fermenation raw liquids；
Further, it is described to be filtered into 30-50 mesh sieves.
4) ageing is extracted
The 12 taste dregs of a decoction that step 3) is obtained by filtration with after Xiaoqu wine ageing 60-90 days, 12 tastes are obtained by filtration in multiple supernatant
Medicine Xiaoqu wine leaching liquor.
Further, the ageing temperature is 15-35 DEG C, and multiple supernatant filters to standing and do not produce precipitation, you can obtains 12
Taste medicine Xiaoqu wine leaching liquor；And the number of degrees of the 12 taste medicine Xiaoqu wine leaching liquor are 55-65 degree.
Xiaoqu wine in this step is also known as medicinal liquor, frequently as the base liquor steep in wine, general Xiaoqu wine.As for Xiaoqu wine
Do not specially required with the amount of the dregs of a decoction, those skilled in the art can voluntarily allocate as needed, for those skilled in the art and
Easy to implement.
5) mix, season
12 taste medicine fermenation raw liquids and 12 taste medicine Xiaoqu wine leaching liquors are mixed, so as to get the mixing medicinal liquor number of degrees be 20-45
Degree, and add sweetener seasoning.
The additive amount of fermentation sucrose at initial stage determines the ethanol content of wine after fermentation.And wine yeast is in high concentration sucrose
Yeasting in, activity can be suppressed, and the fermenation raw liquid number of degrees that the present invention is fermented using wine yeast are not high,
But the fermenation raw liquid taste of traditional Chinese medicine after being fermented by wine yeast can it is soft very much.And the dregs of a decoction and the direct soak medicine of Xiaoqu wine obtain
The general taste of traditional Chinese medicine of leaching liquor arrived is very heavy, influences mouthfeel, so fermenation raw liquid and leaching liquor collocation are reconciled, improves wine degree,
Reduce the bitterness of Chinese medicine.
35 degree of health liquor is the number of degrees of strength wine, fewer in less than 30 degree of wine degree mouthfeel for the crowd generally to drink
It is light but more than 45 degree just high for the crowd of no drinking.For active constituents of medicine stripping property, water extraction can only incite somebody to action
Water-soluble active ingredient extracts in medicine, and many active components in water and dissolve, and dilute alcohol is (namely low
Wine) more active constituents of medicine can be extracted.In addition, the zoopery that we have ever done shows that alcoholic strength is excessive, such as
56 degree, mouse stomach can be caused to damage and cause anorexia dead.It is so of the invention from active constituents of medicine stripping quantity and mouth
The aspect of sense two have selected 20-45 degree alcoholic strengths.
12 taste medicine fermenation raw liquids are 2-8 parts in the mixing medicinal liquor and 12 taste medicine Xiaoqu wine leaching liquors are 1-5 parts.Above-mentioned
In the range of the mixing quality number of restriction, the mixing medicinal liquor taste being prepared is more preferable, and the content of pharmaceutical actives is of a relatively high.
Further, the sweetener is oligoisomaltose and honey, and the addition of oligoisomaltose is 1-6 parts,
The addition of honey is 1-6 parts.The addition of oligoisomaltose and honey can cover the bitter taste of Chinese medicine, additive amount
Later finished wine can be caused to cross sweet tea and stick larynx, it is clouding；Additive amount is too low and finished wine sweet taste can be caused inadequate, slightly bitter taste,
Influence mouthfeel.
6) sterilizing, tinning
Seasoned medicinal liquor sterile filling after pasteurization will be mixed and obtain tonifying kidney and strengthening yang health preserving wine.
It can be extended the shelf life using sterilizing tinning.Further, the temperature of the pasteurization is 65-75 DEG C
A kind of preparation method of tonifying kidney and strengthening yang health preserving wine of the present invention is further described with reference to specific example.
Example 1
The preparation detailed process of this example tonifying kidney and strengthening yang health preserving wine is as follows：
1st, Chinese medicine pre-processes：4 parts of the authentic medicinal herbs fruit of Chinese wolfberry selected by weight, 4 parts of Semen Cuscutae, 4 parts of Schisandra chinensis, cover basin
2 parts of 5 parts of son, 5 parts of plantain seed, 6 parts of Herba Epimedii, 5 parts of Morinda officinalis, 3 parts of Radix Paeoniae Alba, 2 parts of the dried rhizome of rehmannia, 3 parts of Cortex Phellodendri, 2 parts of rhizoma anemarrhenae and maca,
Crush, cross 40 mesh sieves.
2nd, ferment：The above-mentioned Chinese medicine after pulverizing and sieving is loaded into hair together with 3 portions of sucrose, 3 parts of saccharomycete, 30 parts of water
Fermentation tank, is then sealed by fermentation, and 4 weeks before sealing and fermenting, the exhausting-gas hole exhaust of fermenter is opened daily, when zymotic fluid alcoholic strength rises
It is fermentation termination to 10 degree.
3rd, filter：By above-mentioned zymotic fluid with 40 mesh screens, taking supernatant, supernatant filters to standing and does not produce precipitation repeatedly,
Obtain 12 taste medicine fermenation raw liquids.
4th, ageing is extracted：The 12 taste dregs of a decoction that above-mentioned steps are obtained by filtration and Xiaoqu wine ageing 80 days at a temperature of 25 DEG C
Afterwards, multiple supernatant filters to standing and does not produce precipitation, obtains the 12 taste medicine Xiaoqu wine leaching liquors that the number of degrees are 60 degree.
5th, mix, season：6 part of 12 taste medicine fermenation raw liquid and the mixing of 3 part of 12 taste medicine Xiaoqu wine leaching liquor, so as to get mixing
The medicinal liquor number of degrees are 35 degree, and add 3 parts of oligoisomaltoses and 3 parts of honey seasonings.
6th, sterilizing, tinning：Seasoned medicinal liquor sterile filling after 70 DEG C of pasteurizations will be mixed and obtain tonifying kidney and strengthening yang
Health preserving wine.
Example 2
The preparation detailed process of this example tonifying kidney and strengthening yang health preserving wine is as follows：
1st, Chinese medicine pre-processes：6 parts of the authentic medicinal herbs fruit of Chinese wolfberry selected by weight, 5 parts of Semen Cuscutae, 7 parts of Schisandra chinensis, cover basin
2 parts of 8 parts of son, 6 parts of plantain seed, 8 parts of Herba Epimedii, 6 parts of Morinda officinalis, 4 parts of Radix Paeoniae Alba, 4 parts of the dried rhizome of rehmannia, 2 parts of Cortex Phellodendri, 1 part of rhizoma anemarrhenae and maca,
Crush, cross 45 mesh sieves.
2nd, ferment：The above-mentioned Chinese medicine after pulverizing and sieving is loaded into hair together with 2 portions of sucrose, 2 parts of saccharomycete, 20 parts of water
Fermentation tank, is then sealed by fermentation, and 2 weeks before sealing and fermenting, the exhausting-gas hole exhaust of fermenter is opened daily, when zymotic fluid alcoholic strength rises
It is fermentation termination to 15 degree.
3rd, filter：By above-mentioned zymotic fluid with 40 mesh screens, taking supernatant, supernatant filters to standing and does not produce precipitation repeatedly,
Obtain 12 taste medicine fermenation raw liquids.
4th, ageing is extracted：The 12 taste dregs of a decoction that above-mentioned steps are obtained by filtration and Xiaoqu wine ageing 70 days at a temperature of 30 DEG C
Afterwards, multiple supernatant filters to standing and does not produce precipitation, obtains the 12 taste medicine Xiaoqu wine leaching liquors that the number of degrees are 65 degree.
5th, mix, season：8 part of 12 taste medicine fermenation raw liquid and the mixing of 2 part of 12 taste medicine Xiaoqu wine leaching liquor, so as to get mixing
The medicinal liquor number of degrees are 25 degree, and add 4 parts of oligoisomaltoses and 4 parts of honey seasonings.
6th, sterilizing, tinning：Seasoned medicinal liquor sterile filling after 65 DEG C of pasteurizations will be mixed and obtain tonifying kidney and strengthening yang
Health preserving wine.
Example 3
The preparation detailed process of this example tonifying kidney and strengthening yang health preserving wine is as follows：
1st, Chinese medicine pre-processes：2 parts of the authentic medicinal herbs fruit of Chinese wolfberry selected by weight, 2 parts of Semen Cuscutae, 3 parts of Schisandra chinensis, cover basin
1 part of 4 parts of son, 2 parts of plantain seed, 3 parts of Herba Epimedii, 2 parts of Morinda officinalis, 1 part of Radix Paeoniae Alba, 1 part of the dried rhizome of rehmannia, 1 part of Cortex Phellodendri, 1 part of rhizoma anemarrhenae and maca,
Crush, cross 50 mesh sieves.
2nd, ferment：The above-mentioned Chinese medicine after pulverizing and sieving is loaded into hair together with 2 portions of sucrose, 2 parts of saccharomycete, 20 parts of water
Fermentation tank, is then sealed by fermentation, and 3 weeks before sealing and fermenting, the exhausting-gas hole exhaust of fermenter is opened daily, when zymotic fluid alcoholic strength rises
It is fermentation termination to 8 degree.
3rd, filter：By above-mentioned zymotic fluid with 45 mesh screens, taking supernatant, supernatant filters to standing and does not produce precipitation repeatedly,
Obtain 12 taste medicine fermenation raw liquids.
4th, ageing is extracted：The 12 taste dregs of a decoction that above-mentioned steps are obtained by filtration and Xiaoqu wine at a temperature of 25 after ageing 90 days,
Multiple supernatant, which is filtered to standing, does not produce precipitation, obtains the 12 taste medicine Xiaoqu wine leaching liquors that the number of degrees are 55 degree.
5th, mix, season：4 part of 12 taste medicine fermenation raw liquid and the mixing of 2 part of 12 taste medicine Xiaoqu wine leaching liquor, so as to get mixing
The medicinal liquor number of degrees are 30 degree, and add 2 parts of oligoisomaltoses and 2 parts of honey seasonings.
6th, sterilizing, tinning：Seasoned medicinal liquor sterile filling after 75 DEG C of pasteurizations will be mixed and obtain tonifying kidney and strengthening yang
Health preserving wine.
Example 4
The preparation detailed process of this example tonifying kidney and strengthening yang health preserving wine is as follows：
1st, Chinese medicine pre-processes：8 parts of the authentic medicinal herbs fruit of Chinese wolfberry selected by weight, 8 parts of Semen Cuscutae, 6 parts of Schisandra chinensis, cover basin
3 parts of 6 parts of son, 5 parts of plantain seed, 5 parts of Herba Epimedii, 7 parts of Morinda officinalis, 5 parts of Radix Paeoniae Alba, 4 parts of the dried rhizome of rehmannia, 4 parts of Cortex Phellodendri, 3 parts of rhizoma anemarrhenae and maca,
Crush, cross 50 mesh sieves.
2nd, ferment：The above-mentioned Chinese medicine after pulverizing and sieving is loaded into hair together with 4 portions of sucrose, 4 parts of saccharomycete, 45 parts of water
Fermentation tank, is then sealed by fermentation, and 4 weeks before sealing and fermenting, the exhausting-gas hole exhaust of fermenter is opened daily, when zymotic fluid alcoholic strength rises
It is fermentation termination to 15 degree.
3rd, filter：By above-mentioned zymotic fluid with 40 mesh screens, taking supernatant, supernatant filters to standing and does not produce precipitation repeatedly,
Obtain 12 taste medicine fermenation raw liquids.
4th, ageing is extracted：The 12 taste dregs of a decoction that above-mentioned steps are obtained by filtration and Xiaoqu wine ageing 75 days at a temperature of 35 DEG C
Afterwards, multiple supernatant filters to standing and does not produce precipitation, obtains the 12 taste medicine Xiaoqu wine leaching liquors that the number of degrees are 65 degree.
5th, mix, season：8 part of 12 taste medicine fermenation raw liquid and the mixing of 4 part of 12 taste medicine Xiaoqu wine leaching liquor, so as to get mixing
The medicinal liquor number of degrees are 40 degree, and add 3 parts of oligoisomaltoses and 3 parts of honey seasonings.
6th, sterilizing, tinning：Seasoned medicinal liquor sterile filling after 70 DEG C of pasteurizations will be mixed and obtain tonifying kidney and strengthening yang
Health preserving wine.
The functional evaluation for the tonifying kidney and strengthening yang health preserving wine that example 1 to 4 is prepared
Functional evaluation is carried out by taking the tonifying kidney and strengthening yang health preserving wine that example 1 is prepared as an example, what example 2 to 4 was prepared supports
Raw wine can also reach the effect of identical.Specific evaluation procedure is as follows：
In the functional evaluation of tonifying kidney and strengthening yang health preserving wine, we establish kidney-yang deficiency animal model, are prepared by embodiment 1
14 days therapeutic interventions of tonifying kidney and strengthening yang health preserving wine, record by the mouse low temperature swimming time of therapeutic intervention group, measure spleen,
The organ index of thymus gland and reproductive organs.Serum total cholesterol (T-CHO), triacylglycerol (TG), phenylalanine ammonia are measured after taking blood
Base transaminase (ALT), aspartat aminotransferase (AST) biochemical indicator.
Specific therapeutic regimen：SPF grades of KM kind heros mouse 50, are divided into blank control group, model group, tonifying kidney and strengthening yang health preserving wine
High, medium and low dosage group, every group of 10 mouse, totally 5 groups.After conventinal breeding 1 week, experiment is proceeded by.In addition to Normal group,
Each group is injected intraperitoneally hydrocortisone modeling (10mg/kg), 1 times/day, continuous 14d.At the same time tonifying kidney and strengthening yang health preserving wine it is high, in,
Low dose group mouse presses 2.5,1.25,0.625g/kg dosage gastric infusion of crude drug amount respectively, gavage volume 0.1ml/10g, 1 time/
D, model group and blank group gavage equivalent distilled water, continuous 14d.
In various kidney-yang deficiency animal models, the mouse kidney-yang deficiency model of hydrocortisone induction is the classical kidney yang of comparison
Empty animal model, it is prehypophyseal ACTH releases is received suppression with a certain amount of exogenous glucocorticoid, so that
Adrenocortical secretion steroid hormone is reduced, and a series of " exhaustion " phenomenon occurs in animal, and such as hogback, roll up, swim and resistance to
The cold time shortens, limb tail it is cold and it is crowded it is sleeping together.Its Symptoms meets the clinical manifestation of traditional Chinese medical science syndrome of deficiency of kidney yang.
Tcm clinical practice index of the index as close possible to syndrome of deficiency of kidney yang is surveyed in this evaluation.Aversion to cold and cold limbs disease is the one of yang deficiency syndrome
As performance, it is apathetic generally using autonomic activities as index, thus examine or check mouse low temperature swimming time.The cold disease of sexual desire is positioned at kidney,
By decline of kidney-YANG, essence, which is lost, hides and caused, therefore examines or check testis, preputial gland index.The traditional Chinese medical science thinks " The liver and the kidney have a common source " that kidney deficiency is so that liver is lost
Void, may cause hepatic injury, therefore it is horizontal to examine or check ALT, AST in serum.Liver controlling conveyance and dispersion, if liver loses catharsis, depression and stagnation of QI, with
Dysfunction of the spleen is caused, the dysfunction of the spleen in transport, makes vivo protein lipid unbalance, therefore examines or check spleen index and TG, T-CHO biochemical indicator.
1st, the composition detection for the tonifying kidney and strengthening yang health preserving wine that example 1 is prepared
Shown in assay by the tonifying kidney and strengthening yang health preserving wine prepared to example 1 and wherein contain Hyperoside (content
About 0.058%), polysaccharide (content is about 6.6%) and flavones (content of general flavone is 0.55%).Hyperoside is benefit
The main active of kidney and enhancing body, polysaccharide can improve the effect such as immunity, reducing blood lipid, and flavones has hepatoprotective effect.Thus may be used
See, formula of health preserving wine of the present invention and preparation method thereof can play the role of influencing hepatic and renal function.
2nd, influence of the tonifying kidney and strengthening yang health preserving wine that example 1 is prepared to the mice with kidney-yang deficiency ice-swimming time
After tonifying kidney and strengthening yang health preserving wine last dose 2h, each group mouse low temperature swimming time (15 DEG C of water temperature, the depth of water are recorded
20cm, overboard to the time required to being drowned with stopwatch record mouse).
The 1 each group mouse ice-swimming time of table comparison (N=10)
Note：Compared with Normal group, * P<0.05.
Table 1 is shown, compared with Normal group, when tonifying kidney and strengthening yang health preserving wine middle dosage and high dose group low temperature swimming survival
Between conspicuousness extend (P<0.05).
3rd, the tonifying kidney and strengthening yang health preserving wine that example 1 is prepared is immunized mice with kidney-yang deficiency and the influence of sexual organ index
Each group mouse organs' index results are shown in Table 2.Table 2 is shown, compared with normal group, after model group mouse modeling spleen with
Reduce (P to testis index conspicuousness<0.05), thymus index also reduces (P to conspicuousness<0.01) hydrocortisone, is illustrated
(10mg/kg) can induce mouse kidney-yang deficiency；Compared with model group, the spleen after each dosage of tonifying kidney and strengthening yang health preserving wine is administered 14 days refers to
Number has elevated trend, but no difference of science of statistics；Compared with model group, tonifying kidney and strengthening yang health preserving wine low dose group (P<0.05) in,
Dosage group (P<0.05), high dose group (P<0.01) conspicuousness testis index is increased；Preputial gland index and model control group ratio
Compared with no significant difference.
2 each group mice organs index of table comparison (N=10)
Note：Compared with Normal group, * P<0.05, * * P<0.01；Compared with model control group, #P<0.05, ##P<
0.01.Similarly hereinafter.
4th, influence of the tonifying kidney and strengthening yang health preserving wine that example 1 is prepared to mice with kidney-yang deficiency serum TG, T-CHO levels is being mended
Kidney and enhancing body health preserving wine therapeutic intervention is after 14 days, each group mice serum TG, T-CHO measurement result such as table 3.With Normal group ratio
Compared with the horizontal conspicuousnesses of model control group mice serum TG, T-CHO reduce (P<0.05)；Compared with model control group, tonifying kidney and strengthening yang
Health preserving wine high dose group (P<0.05), middle dose group (P<0.05), low dose group (P<0.05) can conspicuousness after being administered 14 days
Rise mice serum TG, T-CHO are horizontal on ground, and difference is statistically significant.
3 each group mouse TG, T-CHO level of table comparison (N=10)
5th, influence of the tonifying kidney and strengthening yang health preserving wine that example 1 is prepared to mice with kidney-yang deficiency serum AST, ALT levels
After tonifying kidney and strengthening yang health preserving wine therapeutic intervention 14 days, each group mice serum AST measurement results such as table 4.With it is normal right
Compare according to group, the horizontal significantly rise (P of model control group mice serum AST<0.01)；Compared with model control group, tonifying kidney and strengthening yang
Health preserving wine high dose group can significantly decrease serum AST levels (P after being administered 14 days<0.05).Illustrate tonifying kidney and strengthening yang health preserving wine
With enzyme level related with liver function in mice with kidney-yang deficiency serum is reduced, improve liver dysfunction.Compared with Normal group,
Model control group mice serum ALT levels have elevated trend, but no difference of science of statistics；Compared with model control group, Bu Shen Zhuang
After administration 14 days, mice serum ALT levels have becoming for decline for positive health preserving wine high dose group, middle dose group, low dosage medication group
Gesture, but no difference of science of statistics.
4 each group mice serum ALT levels of table comparison (N=10)
Tonifying kidney and strengthening yang health preserving wine efficacy assessments the result shows that：1. tonifying kidney and strengthening yang health preserving wine can be obviously prolonged the trip of mouse low temperature
Swim the time-to-live, dramatically increase testis index, Yin Qiganwen returns kidney channel, and energy warming yang for dispelling cold, tonifying kidney and benefiting sperm are so as to improve kidney-yang deficiency
Card.2. the index and spleen index of tonifying kidney and strengthening yang health preserving wine medication group mouse has elevated trend, it is related the spleen channel may to be entered with it.3. kidney tonifying
Establishing-Yang health preserving wine can significantly reduce serum AST, ALT contents is had downward trend, may be with its Return liver kidney, can be by adjusting liver
The relevant enzyme of function is so as to improve liver dysfunction.Show that tonifying kidney and strengthening yang health preserving wine can not only improve mice with kidney-yang deficiency symptom,
Also certain immunoregulation effect.4. tonifying kidney and strengthening yang health preserving wine can raise serum TG, T-CHO levels, may be with its converge to the spleen channel
Related, the main receiving of spleen, transporting, temper build fortune, can balance vivo protein lipid.
In summary：Tonifying kidney and strengthening yang health preserving wine can be obviously prolonged mouse low temperature swimming time, dramatically increase testis and refer to
Number, rise mice serum TG, T-CHO are horizontal, and in addition, tonifying kidney and strengthening yang health preserving wine can also significantly reduce mice serum AST and contain
Amount, makes mice serum ALT contents have downward trend.Kidney can be entered so as to improve waist and knee acid by Wen Yang by illustrating tonifying kidney and strengthening yang health preserving wine
Soft sexual hypoesthesia aversion to cold and cold limbs apathetic kidney-yang deficiency and liver virtual loss.Meanwhile tonifying kidney and strengthening yang health preserving wine also has reduction kidney
The enzyme level related with liver function in deficiency of yang mice serum, improves liver dysfunction and balances the effect of proteolipid.
The influence that 1 different strain of comparative example ferments to health wine taste, ethanol content
Fermentation process selects different strains to produce Different Effects to the content of health wine taste, ethanol.This comparative example 1 is adopted
With three kinds of white wine yeast, wine yeast, wild yeasts different fermentations strains in the case of identical fermentation condition and additive amount
Ferment, compare zymotic fluid flavor, ethanol content, as a result such as table 5 below.
The selection of 5 tonic wine fermenting microbe of table
By table 5 as it can be seen that after three different strains ferment 15 days, the yeast-leavened ethanol content of white wine is 4-8%, grape wine
Yeast fermented wine precision reaches 10-20%, and after wild yeasts bacterium group is fermented 15 days, ethanol content and lactic acid content all compare
Low to be required, it is necessary to extend fermentation time and just reach fermentation, experiment proves that wild yeasts bacterium substantially will be in fermentation 180 days or so
Ethanol content reaches 3-7%.As seen from the above comparison, fermentation time can effectively be shortened using wine yeast fermentation, and
Tart flavour and medicine are moderate in zymotic fluid.
Influence of the different manufacture crafts of comparative example 2 to health preserving wine appearance taste and drug effect
This comparative example designs three kinds and prepares health preserving wine technique, and experiment 1 is simple only to use wine yeast fermenation raw liquid tune taste
Health preserving wine is made；Experiment 2, it is simple that health preserving wine only is made with the Xiaoqu wine 12 taste dregs of a decoction of immersion；Experiment 3, wine yeast is fermented
Stoste adjusts taste that health preserving wine is made after mixing ageing with Xiaoqu wine immersion stoste；According to the standards of grading of table 6, three productions are evaluated
The indexs such as technique health colours of wine, clarity, taste, and the content of Hyperoside in three kinds of process samples is have detected, as a result
It is shown in Table 7.
6 health preserving wine standards of grading of table
7 health preserving wine Different Preparation appraisal result of table and active constituent content
In health preserving wine appraisal result made from 7 various processes of table, directly seasoned using wine yeast fermenation raw liquid
Obtained health preserving wine, ethanol content is relatively low, usually only 15% or so, taste is partially light, and slightly medicinal material is fragrant, Determination of Hyperoside compared with
It is low；Only with the fragrance overrich of health preserving wine Chinese medicine made from Xiaoqu wine soaking technology, wine degree is higher, and Determination of Hyperoside is most
Height, but damage of the excessive ethanol content for health care to stomach is larger.Health made from two kinds of mixing aging process
Wine, has the distinctive fragrance of Chinese medicine, but has lacked the bitter taste of Chinese medicine, the fragrance with moderate Xiaoqu wine, Bu Shen Zhuang
The content of the main component Hyperoside of sun is also higher, meets the requirement of health preserving wine, this is with flavone compound in dilute alcohol
Dissolution rate, which increases, relation.So the present invention have selected two kinds of techniques of wine yeast fermenation raw liquid and herbal medicine immersion and be combined preparation
Tonifying kidney and strengthening yang health preserving wine.
3 sucrose addition of comparative example influences health preserving wine fermenation raw liquid ethanol content
This comparative example designs 4 sucrose additions, after the 15d that ferments, measures the ethanol content of each group fermenation raw liquid, experiment
It the results are shown in Table 8.
Influence of the sucrose addition to fermenation raw liquid ethanol content in 8 zymotic fluid of table
Shown by table 8, for sucrose addition at 2-4 parts, ethanol content is higher in zymotic fluid in zymotic fluid, and adds 6 parts
Sucrose when, zymotic fluid concentration of alcohol rise unobvious, this is because wine yeast under high saccharide ring border activity reduction, from
And cause the reduction of fermenation raw liquid ethanol content.
Effect of 4 Radix Paeoniae Alba of comparative example in tonifying kidney and strengthening yang health preserving wine
We have selected 6 kidney-yin deficiency for meeting tcm diagnosis standard patients, and Symptoms are soreness and weakness of waist and knees, lower limb without
Power, it is easily tired easily dry, have a sleepless night with dreaminess, enuresis nocturna, the volunteer of the symptom such as night sweat, 3 one group of people, are divided into two groups, respectively drink formulation
Two (the tonifying kidney and strengthening yang health preserving wines for not adding Radix Paeoniae Alba) of one (tonifying kidney and strengthening yang health preserving wine of the invention) and formula.It is every daily to take per capita
30ml, after one week, there is night sweat and are clearly better in 3 people for taking formula one, and enuresis nocturna number significantly reduces, and sleep quality improves
Chief complaint；And 3 patients of formula two are taken, although enuresis nocturna is reduced, night sweat symptom does not improve, and sleep quality does not have
It is significantly improved.Radix Paeoniae Alba, bitter, acid, cold nature, has effects that nourishing blood and liver, delays middle analgesic, holds back cloudy receipts sweat, for certainly
Sweat night sweat, fever due to yin deficiency have good therapeutic effect.So the Radix Paeoniae Alba in the tonifying kidney and strengthening yang health preserving wine of the present invention is for kidney-yin deficiency
Spontaneous sweating have good inhibition, can enriching yin and nourishing kidney, correct the symptom of kidney-yin deficiency.
5 dried rhizome of rehmannia of comparative example, the effect of Cortex Phellodendri, rhizoma anemarrhenae in tonifying kidney and strengthening yang health preserving wine
We have selected 4 stay up late, puffiness is easily perspired, thirsty, weak fatiguability, energy is not concentrated, easy fecula thorn, acne
Kidney-yin deficiency patient, first take the tonifying kidney and strengthening yang health preserving wine for not adding the dried rhizome of rehmannia, Cortex Phellodendri, rhizoma anemarrhenae, after a week, weak fatiguability symptom
It is clearly better, but scorching symptom improves unobvious.It is discontinued after two weeks, changes the tonifying kidney and strengthening yang health preserving wine of the clothes present invention, after three days
Scorching, thirsty symptom is clearly better, and acne, acne are clearly better within one week.Kidney-yin deficiency usually damages body fluid since constitution is scorching,
And dried rhizome of rehmannia clearing heat and cooling blood, Yin-nourishing and body fluid promoting；Cortex Phellodendri bitter, cold in nature, the bitter hard kidney of energy, energy heat-clearing of trembling with fear, therefore Cortex Phellodendri has the effect of heavily fortified point kidney；
Rhizoma anemarrhenae is bitter in taste, sweet, trembles with fear, clearing heat-fire, fluid dryness.It is clear that three taste medicines play cool blood in the tonifying kidney and strengthening yang health preserving wine of the present invention
The effect of heat, dry drop of promoting the production of body fluid.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of preparation method of tonifying kidney and strengthening yang health preserving wine, it is characterised in that comprise the following steps：
1) Chinese medicine pre-processes：Fruit of Chinese wolfberry 1-8 parts selected by weight, 1-8 parts of Semen Cuscutae, 1-8 parts of Schisandra chinensis, raspberry 1-8
Part, 1-8 parts of plantain seed, 1-10 parts of Herba Epimedii, 1-10 parts of Morinda officinalis, 1-4 parts of Radix Paeoniae Alba, 1-4 parts of the dried rhizome of rehmannia, 1-4 parts of Cortex Phellodendri, rhizoma anemarrhenae 1-
4 parts and 1-4 parts of maca, crush, sieving；
2) ferment：The above-mentioned Chinese medicine after pulverizing and sieving is loaded into fermentation tank together with sucrose, saccharomycete, water, is then sealed
Fermentation, is fermentation termination when zymotic fluid alcoholic strength rises to 8-17 degree；
3) filter：By above-mentioned filtering fermentation liquor, taking supernatant, supernatant filters to standing and does not produce precipitation repeatedly, obtains 12 taste medicines and sends out
Ferment stoste；
4) ageing is extracted：The 12 taste dregs of a decoction that step 3) is obtained by filtration with after Xiaoqu wine ageing 60-90 days, multiple supernatant filters
To 12 taste medicine Xiaoqu wine leaching liquors；
5) mix, season：12 taste medicine fermenation raw liquids and 12 taste medicine Xiaoqu wine leaching liquors are mixed, so as to get the mixing medicinal liquor number of degrees
For 20-45 degree, and add sweetener seasoning；
6) sterilizing, tinning：Seasoned medicinal liquor sterile filling after pasteurization will be mixed and obtain tonifying kidney and strengthening yang health preserving wine.
A kind of 2. preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that in step 1), the Chinese holly
1-4 parts of matrimony vine, 1-4 parts of Semen Cuscutae, 1-4 parts of Schisandra chinensis, 1-4 parts of raspberry, 1-4 parts of plantain seed, 2-4 parts of Herba Epimedii, Morinda officinalis
1-2 parts of 2-4 parts, 1-2 parts of Radix Paeoniae Alba, 1-2 parts of the dried rhizome of rehmannia, 1-2 parts of Cortex Phellodendri, 1-2 parts of rhizoma anemarrhenae and maca.
A kind of 3. preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that in step 1), the mistake
Sieve as 30-50 mesh sieves.
A kind of 4. preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that in step 2), the sugarcane
Sugar is 1-4 parts, and the saccharomycete is 1-4 parts, and water is 20-50 parts；1-4 weeks before the sealing and fermenting, fermenter is opened daily
Exhausting-gas hole is vented.
A kind of 5. preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that in step 3), the mistake
Filter as 30-50 mesh sieves.
A kind of 6. preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that in step 4), described 12
The number of degrees of taste medicine Xiaoqu wine leaching liquor are 55-65 degree.
7. a kind of preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that described mixed in step 5)
12 taste medicine fermenation raw liquids are 2-8 parts in conjunction medicinal liquor and 12 taste medicine Xiaoqu wine leaching liquors are 1-5 parts.
A kind of 8. preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that in step 5), the sweet tea
Taste agent is oligoisomaltose and honey, and the addition of oligoisomaltose is 1-6 parts, and the addition of honey is 1-6 parts.
A kind of 9. preparation method of tonifying kidney and strengthening yang health preserving wine as claimed in claim 1, it is characterised in that in step 6), described bar
The temperature of family name's sterilizing is 65-75 DEG C.
10. a kind of tonifying kidney and strengthening yang health preserving wine, it is characterised in that be prepared into using the preparation method described in the claims 1 to 9
Arrive.
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