CN109221664A - A kind of Chinese medicinal herb chicken feed - Google Patents

A kind of Chinese medicinal herb chicken feed Download PDF

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Publication number
CN109221664A
CN109221664A CN201811056364.6A CN201811056364A CN109221664A CN 109221664 A CN109221664 A CN 109221664A CN 201811056364 A CN201811056364 A CN 201811056364A CN 109221664 A CN109221664 A CN 109221664A
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China
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parts
chinese
egg
chicken
chicken feed
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CN201811056364.6A
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Chinese (zh)
Inventor
张晓华
韩京朋
布艳伟
罗丹
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Wuhan Wik Biotechnology Co Ltd
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Wuhan Wik Biotechnology Co Ltd
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Priority to CN201811056364.6A priority Critical patent/CN109221664A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds

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  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Health & Medical Sciences (AREA)
  • Fodder In General (AREA)

Abstract

The present invention provides a kind of Chinese medicinal herb chicken feed, this chicken feed contains following bulk pharmaceutical chemicals: 2-5 parts of allicin, 20-50 parts of the Chinese bulbul, 10-40 parts of Chinese yam, 10-40 parts of purple perilla, 10-40 parts of Cortex Eucommiae, 10-40 parts of lophatherum gracile, 20-40 parts of Radix Astragali, 20-40 parts of Radix Angelicae Sinensis, 20-40 parts of cichory root, 20-40 parts of Radix Glycyrrhizae.High laying hen immunity of organisms, disease prevention ability can significantly be caught by being to provide one kind by practical proof its effect;The features such as mouthfeel for improving egg, improves the nutritive value of egg, enhances the health-care effect of egg, and cost is relatively low by the present invention, is suitable for universal egg feedstuff, and easy to process, cost feedstocks are extensive, cheap, market prospects are very considerable.

Description

A kind of Chinese medicinal herb chicken feed
Technical field
The present invention relates to a kind of feed, i.e., a kind of Chinese medicinal herb chicken feed.
Background technique
Currently, the produced egg yield of the laying hen of Scale dependency is high, single volume is big, but taste and nutritive value are often not so good as The produced egg of common farmers' laying hen, but also the major issues such as immunity degradation of generally existing laying hen, thus how to improve Always R&D Professional faced and how to improve the problems such as immunity of laying hen, laying rate, the nutritive value of egg and mouthfeel With the thing of raising.The reason of forming this situation is various, but family chicken free-ranging, freedom of action, physical health should be A very direct reason.Studies have shown that the laying hen of Scale dependency all uses cage to raise, limitation of activity, constitution is obviously not so good as house Chicken, especially functions of intestines and stomach and ovarian function and free-ranging family chicken have significant difference.If the constitution of batterylaying can be improved, Especially improve its functions of intestines and stomach and ovarian function, improve the quality laid eggs, reduce the poor quality of cage egg and family's egg away from The always matter of utmost importance of batterylaying.Therefore, the constitution of laying hen is improved by changing the ingredient of feed, becomes raising cage The important channel of Egg Production of Laying Hens quality.Although the nutrition comparison of existing egg feedstuff is comprehensive, lacks and improve immunity of organisms, change Kind organ dysfunction and the medicinal ingredient prevented and cured diseases, and be used for the drug of chicken disease control, not only higher cost, but also have one Fixed side effect cannot be commonly used.And the common egg feedstuff of market today mainly includes supplement albumen, vitamin, microelement With the energy feeds such as calcareous concentrated feed and corn.For technical standpoint, documents CN101095461 B, CN1709133 A, CN101181018 B etc., although going to improve egg quality from different aspect in different ways, going to improve laying hen Immunity, but apply or face ordinary people with high content of technology be difficult to carry out or face implement technical solution brought by it is at high cost Etc. technological deficiencies.In addition, the egg of existing scale chicken house production still lack crowd general lack of selenium, calcium, zinc nutrition element, with And amino acid required for old man and children.Though there is expert by feeding special Feed Manufacturing egg containing selenium in recent years, generate Cost and price is all very high, is easy to excess generation harm, is difficult to universal and applies for a long time.
Summary of the invention
Above-mentioned technical problem is realized by the following technical solutions: provide a kind of Chinese medicinal herb chicken feed, by Chinese herbal medicine with Complete diet pellet is formulated by 1:100 weight ratio.
The Chinese herbal medicine is made of following bulk pharmaceutical chemicals: 2-5 parts of allicin, 20-50 parts of the Chinese bulbul, and 10-40 parts of Chinese yam, purple perilla 10-40 parts, 10-40 parts of Cortex Eucommiae, 10-40 parts of lophatherum gracile, 20-40 parts of Radix Astragali, 20-40 parts of Radix Angelicae Sinensis, 20-40 parts of cichory root, Radix Glycyrrhizae 20-40 parts.
Preferably, Chinese herbal medicine is prepared from the following raw materials: allicin 2g, Chinese bulbul 20g, Chinese yam 10g, purple perilla 10g, Cortex Eucommiae 10g, lophatherum gracile 10g, Radix Astragali 20g, Radix Angelicae Sinensis 20g, cichory root 20g, Radix Glycyrrhizae 20g.
Chicken feed provided by the invention can significantly catch high laying hen immunity of organisms, disease prevention ability;Improve the mouthfeel of egg, The nutritive value for improving egg enhances the health-care effect of egg, and cost is relatively low by the present invention, is suitable for universal egg feedstuff, and add The features such as work is convenient, cost feedstocks are extensive, cheap, market prospects are very considerable.
Specific embodiment
1 Chinese herbal medicine formula of embodiment
Formula 1: allicin 2g, Chinese bulbul 20g, Chinese yam 10g, purple perilla 10g, Cortex Eucommiae 10g, lophatherum gracile 10g, Radix Astragali 20g, Radix Angelicae Sinensis 20g, cichory root 20g, Radix Glycyrrhizae 20g.
It is formulated 2: allicin 5g, Chinese bulbul 50g, Chinese yam 40g, purple perilla 40g, Cortex Eucommiae 40g, lophatherum gracile 40g, Radix Astragali 40g, when Return 40g, cichory root 40g, Radix Glycyrrhizae 40g.
It is formulated 3: allicin 3g, Chinese bulbul 30g, Chinese yam 25g, purple perilla 25g, Cortex Eucommiae 25g, lophatherum gracile 25g, Radix Astragali 25g, when Return 25g, cichory root 25g, Radix Glycyrrhizae 25g.
It is formulated 4: allicin 2g, Chinese bulbul 30g, Chinese yam 25g, purple perilla 25g, Cortex Eucommiae 25g, lophatherum gracile 25g, Radix Astragali 25g, when Return 25g, cichory root 25g, Radix Glycyrrhizae 25g.
It is formulated 5: allicin 5g, Chinese bulbul 30g, Chinese yam 25g, purple perilla 25g, Cortex Eucommiae 25g, lophatherum gracile 25g, Radix Astragali 25g, when Return 25g, cichory root 25g, Radix Glycyrrhizae 25g.
Embodiment 2: Chinese herbal medicine preparation
(1) allicin and beta-cyclodextrin are weighed respectively in 1:8 ratio, is configured to satisfy by beta-cyclodextrin under the conditions of 30-40 DEG C And aqueous solution, allicin is mixed with the saturated solution, 30 DEG C of constant temperature constant speed stir 40 hours, and 4 DEG C stand, filter, at 40 DEG C Under the conditions of be dried to get allicin-β-cyclodextrin inclusion complex.Inclusion compound is crushed to 100 mesh fine powders.
(2) the various composition medicine materical crude slice in prescription is taken, is respectively crushed into 100 mesh fine powders, then crush through micronizer, until 500 mesh percent of pass >=95%, are made the Ultramicro-powder of various components.
(3) each component Ultramicro-powder, Chinese bulbul 35g, Chinese yam 35g, purple perilla 35g, Cortex Eucommiae 25g, lophatherum gracile are weighed by weight 30g, Radix Astragali 30g, Radix Angelicae Sinensis 30g, cichory root 25g, Radix Glycyrrhizae 25g, mixing 5-15 minutes to uniform.
(4) mixture in step (3) is added in allicin-β-cyclodextrin inclusion complex, mixing 5-15 minutes to uniform.
Embodiment 3: Chinese herbal feed preparation
The Chinese herbal medicine prepared and chicken complete diet pellet are mixed according to the weight ratio of 1:100, Chinese medicinal herb chicken feed can be obtained.
Embodiment 4: prevention and the tentative clinical test of the treatment white scour of chicken
1 materials and methods
1.1 for reagent product
Chinese herbal granules of the present invention, every 1L water, 10g are dissolved using warm water, and 2 times a day or 5-7 is used in conjunction in every 1kg feed, 20g It.
1.2 experimental animal
350 white plumage broiler chicks of 0 age in days health, are purchased from certain chicken house of Shenyang, are transported to our company's laboratory pouity dwelling place cage, conventional Management feeds complete diet pellet.Selecting 5 chick does not carry the pathogens such as Escherichia coli, salmonella through laboratory testing at random, It can be considered that chicken is used in test.Wherein 50 are used to attack toxic dose preliminary experiment, remaining 300 test is randomly divided into 5 with healthy chicken Group, wherein 1 group is chemoprophylaxis group of the present invention, 1 age in days starts successive administration 5 days, and administration carries out attacking poison on the 4th day;2 groups are this hair Bright medication therapy groups, 2 ages in days start to attack poison, occur after symptom successive administration 5 days;3 groups be negative control group, 1 age in days start to Medicine, successive administration 5 days;4 groups are positive controls, are not administered, 2 ages in days carry out attacking poison;5 groups are healthy control group, normal to raise, It is not administered and does not attack poison;6 groups are safe control group, and 1 age in days is used in healthy test chicken according to 5 times of drug recommended doses of the present invention Only, successive administration 5 days.
1.3 salmonella artificial challenge's dosage experiments
1.3.1 strain separating is identified
This experiment is detected by Beijing Whiskas animal health and evaluates the progress of cloud center, the liver pathological material of disease 1- of aseptic collection clinic diseased chicken 2g after shredding, is put into the test tube equipped with the brilliant green peptone enrichment liquid of 10ml, cultivates 24 hours and increased in 37 DEG C of incubators Bacterium.Take in Zengjing Granule object streak inoculation to S.S Selective agar medium, 37 DEG C incubator culture 24 hours.In S S agar plate culture Visible doubtful bacterium colony is semi-transparent clear, part bacterium colony Intermediate Gray black on base.Choose single doubtful colony inoculation nutrient agar After purifying culture, a little pure culture smear Grain stain microscopy is taken, isolated strains pure culture is separately taken to carry out biochemical test mirror It is fixed.And the salmonella pure culture of separated identification and the genomic DNA of reference strain are extracted, carry out PCR identification.
1.3.2 the preparation of test bacteria liquid
The salmonella identified through PCR is inoculated in after sterile vegetative meat soup carries out increasing bacterium, gram stain microscopy is raw without miscellaneous bacteria Long, as test bacteria liquid, and carrying out count plate with plate dilution method is about 1 × 108CFU/ml。
1.3.3 attacking toxic dose preliminary experiment
50 0 Japanese instar chicklings of health are divided into 5 groups, every group 10.1-4 group is infected group, the 2 chicken inoculation bacterium solutions of age in days each group every 0.5ml, bacterium amount are respectively 0.9 × 105It is a, 0.6 × 105It is a, 0.3 × 105It is a, 0.15 × 105It is a;5 groups of control group necks are subcutaneous It is inoculated with 0.5ml physiological saline.According to morbidity, lesion and lethal cases, inoculation 0.3 × 10 is finally determined5CFU/ml bacterium solution 0.5ml Malicious amount is attacked for test.
1.4 test method
In addition to negative control group, healthy control group, safe control group, every chicken neck inoculates 0.3 × 105A Salmonella Bacterium.Attack poison 4 hours, chick shows lassitude, and villus is loose, and necking down eye closing lethargic sleep is reluctant to walk about, poor appetite, diseased chicken paste Anus draws the loose stools of white lime white sample.Dissect diseased chicken hepatomegaly, there are many needle point size blutpunkte or white necrosis region, Spleen enlargement, small intestine, rectum have blutpunkte.Pathological tissues contact is dyed, salmonella is diagnosed as.
The test of table 1 grouping, drug-treated and experiment process
2 test results
Start it is for oral administration be administered to experiment and terminate, the death rate of each group chicken and weight gain are shown in Table 2.
Weight gain: according to 0 age in days of chicken on-test, 7 ages in days, 10 age in days each group chicken average weights calculate after the test The average weight gain of every group of test chicken.Body weight increase rate is calculated by the ratio between weight gain of each medication treatment group and healthy control group, Wherein healthy control group chicken rate of body weight gain is set as 100%.
The 2 each group chicken death rate of table and body weight increase rate compare
3 conclusions
3.1 curative effect of medication of the present invention
The death rate of chemoprophylaxis group of the present invention is lower, and only 4% is dead compared with negative control group, hence it is evident that is lower than positive control The group death rate 78%;And also below 16% death rate of healthy control group.Illustrate that drug is preferable for the preventive effect of the white scour of chicken, Survival rate is better than the healthy control group normally raised.
The death rate of medication therapy groups of the present invention is 18%, unobvious with 16% difference of the healthy control group death rate, hence it is evident that low In the positive controls death rate 78%, illustrate that drug is preferable to the therapeutic effect of the white scour of chicken, survival rate and the health normally raised Control group is not much different.
Influence of 3.2 drugs of the present invention to weight gain
In experimentation, hence it is evident that visible administration group (prevention group, negative control group) chicken opens food early, and appetite is preferable, and spiritual shape State is active compared with other groups, illustrates that drug of the present invention has attractant effect to the young bird chicken for just going out shell, and to enhancing body resisting stress There is certain effect with anti-fatigue ability.
7 ages in days, prevention group, treatment group the relative weight gain be slightly below negative control group, but be higher than healthy control group;And Prevention group when 10 age in days, treatment group, negative control group the relative weight gain be still higher than healthy control group, illustrate drug have promote it is young Chicken feeding, improves digestion and absorption function, the effect put on weight.
Drug usage amount of the present invention is to be used in conjunction 5-7 days, and 5 days i.e. visible positive effect is used continuously in this experiment.
3.3 drug safeties of the present invention
During safe control group medication, the chicken state of mind, feeding, excrement are normal, and internal organs and tissue have no after dissect Abnormal, rate of body weight gain and negative control group no significant difference illustrate that drug of the present invention is safe to target animals chicken.
Embodiment 4: the expansion clinical test of drug of the present invention
1 chicken public sentiment condition
One raiser of Tieling Xifeng area, the white meat-type chickens of batch raising on the raiser, brooding, 4 age in days of period is broken out With yolk malabsorption, liver enlargement, petechial hemorrhage simultaneously have focal necrosis, arrange what white paste sample excrement, paste anus etc. were characterized Disease.By clinical symptoms, dissect and laboratory diagnosis, it is diagnosed as DISEASE IN FLOCKS.Through speculating, cause of disease may be incubator dirt Dye or feeding environment pollution.After Enrofloxacin is used in conjunction 5 days, substantially control the state of an illness, survival rate about 81%.
2 test methods
Also once there is such disease in the past in the farm, was traditionally treated using antibiotics, to a certain degree On can control it is dead continue to increase, but be also easy to produce drug resistance and medicament residue, and later period death and culling rate is larger.This test This henhouse is continued to use, henhouse is cleared up and is sterilized, after vacant 1 week, into young 6000, points 2 groups, 1 group of feeding drug of the present invention, Every 1L water, 10g;2 groups as a control group, are not administered, and the test period is 7 days, specifically see the table below:
The test of table 1 grouping and drug-treated
Group Chicken number (only) Drug Usage and dosage Start administration time Medication number of days
1 group 3000 Drug of the present invention Every 1L water, 10g 1 age in days 7
2 groups 3000 - - - -
3 test results:
The 2 each group chicken death rate of table and body weight increase rate compare
As a result, 1 group of chicken spirit is more active, two legs are stood solid, feather gloss, are held in the hand and are felt to have fat, full, struggle has Power, Anal cleaning is without dirt.There is salmonella infection symptom or weak young and dead in only individual fragmentary chickens.
There are individual chickens appearance apathetic for 2 groups when 3 age in days, loss of appetite, wing is sagging, stays and stands, is reluctant to walk about, closes mesh Lethargic sleep, some ash discharge white watery stools.Through laboratory testing, salmonella infection is made a definite diagnosis.The chicken that symptom occurs in 4-6 age in days increases More, dead more, 7 ages in days give drug of the present invention to be treated after the test, and 10 age in days jumpbogroups are improved, and further verify The effect of the Chinese medicine.
According to the clinical symptoms, the death rate and weight gain of 2 groups of chickens, prevention and treatment chick that can be fabulous using drug of the present invention is husky Door Salmonella infection, is not likely to produce drug resistance, chick survival rate can reach 98%.
The stage of brooding is the foundation phase of chicken, and outstanding 7 age in days weight of broiler chicken means broiler chicken in growth period hair of brooding It educates well, 4 times of weight when chick weight should be hatching, the every increase 1g of weight just influences whether that the later period delivers body weight increase for sale 25g to 50g delivers the broiler chicken later period for sale and has higher survival rate, feed conversion rate and the uniformity.Therefore, 7 age in days of broiler chicken is improved Can weight, which obtain higher economic benefit to broiler feeding person, seems extremely important.Pass through above-mentioned 2 Clinic Cases, it was demonstrated that this Invention drug when for chick opening medicine there is bacterial diarrhea caused by preferably prevention and treatment Escherichia coli, salmonella etc. to make With, and improving survivability of chicks, significant effect in terms of rate of body weight gain, and in use process safely, effectively, noresidue, have compared with Good economic benefit and social benefit.

Claims (3)

1. a kind of Chinese medicinal herb chicken feed, which is characterized in that chicken feed be prepared by Chinese herbal medicine and complete diet pellet by 1:100 weight ratio and At.
2. Chinese medicinal herb chicken feed according to claim 1, which is characterized in that the Chinese herbal medicine is made of following bulk pharmaceutical chemicals: 2-5 parts of allicin, 20-50 parts of the Chinese bulbul, 10-40 parts of Chinese yam, 10-40 parts of purple perilla, 10-40 parts of Cortex Eucommiae, 10-40 parts of lophatherum gracile, 20-40 parts of Radix Astragali, 20-40 parts of Radix Angelicae Sinensis, 20-40 parts of cichory root, 20-40 parts of Radix Glycyrrhizae.
3. Chinese medicinal herb chicken feed according to claim 2, which is characterized in that the Chinese herbal medicine is prepared from the following raw materials: big Allicin 2g, Chinese bulbul 20g, Chinese yam 10g, purple perilla 10g, Cortex Eucommiae 10g, lophatherum gracile 10g, Radix Astragali 20g, Radix Angelicae Sinensis 20g, cichory root 20g, Radix Glycyrrhizae 20g.
CN201811056364.6A 2018-09-11 2018-09-11 A kind of Chinese medicinal herb chicken feed Pending CN109221664A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104082530A (en) * 2014-06-13 2014-10-08 思南县常青种养专业合作社 Chinese herbal medicine additive for chicken feed
CN106692711A (en) * 2015-07-21 2017-05-24 沈阳伟嘉牧业技术有限公司 Traditional Chinese medicine drug granule of nestling initial drug and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104082530A (en) * 2014-06-13 2014-10-08 思南县常青种养专业合作社 Chinese herbal medicine additive for chicken feed
CN106692711A (en) * 2015-07-21 2017-05-24 沈阳伟嘉牧业技术有限公司 Traditional Chinese medicine drug granule of nestling initial drug and preparation method thereof

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Application publication date: 20190118