CN103598426B - For improving feed addictive and the feed of growth performance of chicks - Google Patents

For improving feed addictive and the feed of growth performance of chicks Download PDF

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CN103598426B
CN103598426B CN201310476920.6A CN201310476920A CN103598426B CN 103598426 B CN103598426 B CN 103598426B CN 201310476920 A CN201310476920 A CN 201310476920A CN 103598426 B CN103598426 B CN 103598426B
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chinese herbal
feed additive
rhizome
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CN103598426A (en
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黄立
曲哲会
郭晓秋
李迎晓
王瑞
焦凤超
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Xinyang Agriculture and Forestry University
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Abstract

The invention provides a kind of feed for improving growth performance of chicks, it comprise corn, wheat bran, the dish dregs of rice, albumen powder, galactomannan, VBT, soybean lecithin, Bee Pollen, salt, sodium bicarbonate, amino acid additive, vitamine supplement, for improving the Chinese herbal feed additive of growth performance of chicks, trace mineral supplement and microorganism formulation.This feed can promote Chicks ' Growth, disease preventing and treating, enhancing animal body resistance, improve efficiency of feed utilization and safety economy material benefit etc. feature, and low toxicity, have no side effect, noresidue.

Description

For improving feed addictive and the feed of growth performance of chicks
Technical field
The present invention relates to technical field of Chinese medicine, particularly relating to the Chinese medicine composition feed addictive for improving growth performance of chicks and feed.
Background technology
Along with the enhancing of the progress of society, the raising of living standards of the people and health perception, people have been familiar with the substantial connection of food and human health.When people select animal products, not only require nutritious but also require safety, health, health care.Since China's accession to WTO, the international market paces of animal products are accelerated further, develop nuisanceless animal husbandry, produce stockbreeding product, strengthen the market competitiveness of China's livestock products, become the top priority of herding authorities of the Chinese government.
It is one of important industry of China's animal husbandry development that commercial meat bird is produced, a mainstay of Ye Shi China livestock products foreign exchange earning.For a long time, China's broiler production edge is main body in order to vaccine, environmental Kuznets Curves, coordinate chemical drug, antibiotic animal doctor prevents epidemic system, consequently chemicals, hormone, antibiotic residue, animal is caused to produce drug resistance, cause carcinogenic, teratogenesis and mutagenesis, and healthy by food chain harm humans, very large threat is constituted to human health and public health.
In addition, the developed countries such as China broiler chicken product main exit America and Europe, Japan, Korea S, these countries have formulated strict standard to the microbiological contamination of import animal products, medicine are residual etc., and China's part commercial meat bird also exists serious medicament residue problem in producing always, thus result in the difficult present situation of chicken outlet, constrain the healthy and stable development of Chicken industry, especially after accession to WTO, foreign government is often as the broiler chicken product of excuse refusal import China.Chinese herbal feed additive is in modernization, intensive farm are produced, play Chinese herbal medicine disease-prevention health, product that growth promoting effects, the superiority development such as to have no drug resistance get up, have natural sex, multifunctionality, toxic and side effect little, not easily in meat, produce the advantages such as hazard residue and day by day favored, along with improving constantly of living standards of the people, the self health consciousness of people strengthens gradually, using Chinese herbal medicine as Additive Production green non-pollution animal products, be more and more subject to the extensive concern of society.
China's traditional Chinese medicine is of extensive knowledge and profound scholarship, and herbal medicine is the rarity of China.In recent years, along with the requirement of people to food security is more and more higher, the research and development of Chinese herbal feed additive caused the great attention of people again.Herbal medicine is natural organic matter inherently, has natural sex, has no side effect, without features such as the resistances to the action of a drug, effectively can reduce the medicament residue of animal products.Composition contained by Chinese herbal feed additive is varied, mainly contains alkaloid, glucoside, organic acid, volatile oil, protein, enzyme, vitamin, polysaccharide, tannin and inorganic salts etc.Chinese herbal feed additive is added in the daily ration of poultry, significantly can strengthen the physique of poultry, improve the immunity of body and antibody horizontal, not only there is prevent disease and alleviate stress effect, the weightening finish of chicken, laying rate, survival rate, reduction feedstuff-meat ratio can also be improved, improve the quality of poultry product.Therefore herbal medicine is also just further important as the effect in feed addictive at home and abroad livestock and poultry cultivation.
The present invention is exactly on this basis, a kind of Chinese medicine composition feed addictive for improving growth performance of chicks is proposed, its can promote Chicks ' Growth, disease preventing and treating, enhancing animal body resistance, improve efficiency of feed utilization and safety economy material benefit etc. feature, and low toxicity, have no side effect, noresidue.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine composition feed addictive for improving growth performance of chicks and feed, its can promote Chicks ' Growth, disease preventing and treating, enhancing animal body resistance, improve efficiency of feed utilization and safety economy material benefit etc. feature, and low toxicity, have no side effect, noresidue.
For solving the problems of the technologies described above, the invention provides a kind of feed for improving growth performance of chicks, it comprise corn, wheat bran, the dish dregs of rice, albumen powder, galactomannan, VBT, soybean lecithin, Bee Pollen, salt, sodium bicarbonate, amino acid additive, vitamine supplement, for improving the Chinese herbal feed additive of growth performance of chicks, trace mineral supplement and microorganism formulation.
Wherein, in described feed, the weight portion of each material composition is respectively corn 80 weight portion ~ 90 weight portion, wheat bran 8 weight portion ~ 12 weight portion, the dish dregs of rice 8 weight portion ~ 12 weight portion, albumen powder 1 weight portion ~ 3 weight portion, galactomannan 2 weight portion ~ 4 weight portion, VBT 1 weight portion ~ 3 weight portion, soybean lecithin 3 weight portion ~ 5 weight portion, Bee Pollen 2 weight portion ~ 4 weight portion, salt 0.5 weight portion ~ 1.5 weight portion, sodium bicarbonate 2 weight portion ~ 4 weight portion, amino acid additive 4 weight portion ~ 6 weight portion, vitamine supplement 4 weight portion ~ 6 weight portion, for improving Chinese herbal feed additive 10 weight portion ~ 15 weight portion of growth performance of chicks, trace mineral supplement 2 weight portion ~ 4 weight portion and microorganism formulation 2 weight portion ~ 4 weight portion.
Wherein, the bulk drug that described Chinese herbal feed additive comprises has the bighead atractylodes rhizome, spina date seed, mantis egg-case, the vine of multiflower knotweed, Changshan, hawthorn, saline cistanche, radix pseudostellariae, folium panacis japonici cum caule, wilsonii, Chinese yam, the rhizome of davallia, the stem of noble dendrobium, the fruit of glossy privet, asparagus fern, honeysuckle, the fruit of Chinese wolfberry, hairyvein agrimony, the root of herbaceous peony, rhizoma zingiberis, mistletoe, the coptis, great burdock achene, cassia twig, Radix Isatidis, pilose gerbera herb, Virgin's milk mushroom, fokien angiopteris rhizome and water bean cotyledon.
Wherein, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 35 weight portion ~ 45 weight portion, spina date seed 20 weight portion ~ 30 weight portion, mantis egg-case 25 weight portion ~ 35 weight portion, the vine of multiflower knotweed 30 weight portion ~ 40 weight portion, Changshan 15 weight portion ~ 25 weight portion, hawthorn 30 weight portion ~ 40 weight portion, saline cistanche 35 weight portion ~ 45 weight portion, radix pseudostellariae 40 weight portion ~ 50 weight portion, folium panacis japonici cum caule 30 weight portion ~ 40 weight portion, wilsonii 25 weight portion ~ 35 weight portion, Chinese yam 30 weight portion ~ 40 weight portion, the rhizome of davallia 20 weight portion ~ 30 weight portion, the stem of noble dendrobium 35 weight portion ~ 45 weight portion, the fruit of glossy privet 25 weight portion ~ 35 weight portion, asparagus fern 20 weight portion ~ 30 weight portion, honeysuckle 45 weight portion ~ 55 weight portion, the fruit of Chinese wolfberry 30 weight portion ~ 40 weight portion, hairyvein agrimony 20 weight portion ~ 30 weight portion, the root of herbaceous peony 35 weight portion ~ 45 weight portion, rhizoma zingiberis 15 weight portion ~ 25 weight portion, mistletoe 25 weight portion ~ 35 weight portion, the coptis 55 weight portion ~ 65 weight portion, great burdock achene 20 weight portion ~ 30 weight portion, cassia twig 25 weight portion ~ 35 weight portion, Radix Isatidis 45 weight portion ~ 55 weight portion, pilose gerbera herb 35 weight portion ~ 45 weight portion, Virgin's milk mushroom 20 weight portion ~ 30 weight portion, fokien angiopteris rhizome 25 weight portion ~ 35 weight portion and water bean cotyledon 30 weight portion ~ 40 weight portion.
Wherein, the preparation method of described Chinese herbal feed additive, is specially:
Above-mentioned raw materials medicine component is mixed by weight, obtains mixture, put into reactor, add the water relative to mixture quality 3 ~ 5 times, slow fire heating decoction 2 ~ 4 hours, decoction liquor is filtered, filter residue adds the water relative to the mixture quality obtained 2 ~ 4 times above, again slow fire boiling 1 ~ 3 hour, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
Present invention also offers the preparation method of above-mentioned feed, it comprises:
The first step, get 3kg microbe additive to join in 50kg ~ 100kg water and mix, obtain zymotic fluid, 85kg corn, 10kg wheat bran, the 10kg dish dregs of rice are mixed, obtain mixture, getting the zymotic fluid that 100kg obtains above joins in the mixture obtained above, and evenly pack is closed, and is placed in the environment of 20 DEG C ~ 30 DEG C and obtains fermentation material after 10 ~ 20 days;
Second step, prepares Chinese herbal feed additive according to the method described above;
3rd step, fodder mixing machine is put into together with the Chinese herbal feed additive that the fermentation material first step obtained and second step obtain and other components, continuous uniform stirs after 1 ~ 3 hour, put into pulverizer tentatively to pulverize, putting into micronizer after taking-up again, to carry out separating twice be fine grained, and the fine grained after pulverizing gets product feed after sterilization, sealing, pack.
Present invention also offers a kind of Chinese herbal feed additive for improving chick meat, it bulk drug comprised has the bighead atractylodes rhizome, spina date seed, mantis egg-case, the vine of multiflower knotweed, Changshan, hawthorn, saline cistanche, radix pseudostellariae, folium panacis japonici cum caule, wilsonii, Chinese yam, the rhizome of davallia, the stem of noble dendrobium, the fruit of glossy privet, asparagus fern, honeysuckle, the fruit of Chinese wolfberry, hairyvein agrimony, the root of herbaceous peony, rhizoma zingiberis, mistletoe, the coptis, great burdock achene, cassia twig, Radix Isatidis, pilose gerbera herb, Virgin's milk mushroom, fokien angiopteris rhizome and water bean cotyledon.
Wherein, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 35 weight portion ~ 45 weight portion, spina date seed 20 weight portion ~ 30 weight portion, mantis egg-case 25 weight portion ~ 35 weight portion, the vine of multiflower knotweed 30 weight portion ~ 40 weight portion, Changshan 15 weight portion ~ 25 weight portion, hawthorn 30 weight portion ~ 40 weight portion, saline cistanche 35 weight portion ~ 45 weight portion, radix pseudostellariae 40 weight portion ~ 50 weight portion, folium panacis japonici cum caule 30 weight portion ~ 40 weight portion, wilsonii 25 weight portion ~ 35 weight portion, Chinese yam 30 weight portion ~ 40 weight portion, the rhizome of davallia 20 weight portion ~ 30 weight portion, the stem of noble dendrobium 35 weight portion ~ 45 weight portion, the fruit of glossy privet 25 weight portion ~ 35 weight portion, asparagus fern 20 weight portion ~ 30 weight portion, honeysuckle 45 weight portion ~ 55 weight portion, the fruit of Chinese wolfberry 30 weight portion ~ 40 weight portion, hairyvein agrimony 20 weight portion ~ 30 weight portion, the root of herbaceous peony 35 weight portion ~ 45 weight portion, rhizoma zingiberis 15 weight portion ~ 25 weight portion, mistletoe 25 weight portion ~ 35 weight portion, the coptis 55 weight portion ~ 65 weight portion, great burdock achene 20 weight portion ~ 30 weight portion, cassia twig 25 weight portion ~ 35 weight portion, Radix Isatidis 45 weight portion ~ 55 weight portion, pilose gerbera herb 35 weight portion ~ 45 weight portion, Virgin's milk mushroom 20 weight portion ~ 30 weight portion, fokien angiopteris rhizome 25 weight portion ~ 35 weight portion and water bean cotyledon 30 weight portion ~ 40 weight portion.
The preparation method of described Chinese herbal feed additive, is specially:
Above-mentioned raw materials medicine component is mixed by weight, obtains mixture, put into reactor, add the water relative to mixture quality 3 ~ 5 times, slow fire heating decoction 2 ~ 4 hours, decoction liquor is filtered, filter residue adds the water relative to the mixture quality obtained 2 ~ 4 times above, again slow fire boiling 1 ~ 3 hour, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
Beneficial effect of the present invention:
Chinese medicine composition feed addictive for improving growth performance of chicks provided by the invention and feed, its can promote Chicks ' Growth, disease preventing and treating, enhancing animal body resistance, improve efficiency of feed utilization and safety economy material benefit etc. feature, and low toxicity, have no side effect, noresidue.
Detailed description of the invention
The trophism of Chinese herbal feed additive is mainly reflected in Chinese herbal medicine containing the necessary various nutriment of animal growth, as protein, amino acid, vitamin, trace element etc., thus diet nutrient full price can be promoted, containing various active composition in Chinese herbal medicine, there is sterilization, antibacterial effect, to Escherichia coli, Gold production staphylococcus, Diplococcus pneumopniae, streptococcus all has certain inhibitory action, polysaccharide in Chinese herbal medicine, alkaloid, organic acid volatilization wet goods has the effect strengthening immunity, Chinese herbal medicine can also improve collective defense resistance and regulate mitigation to swash original work to be used, body is regulated and improves physiological function, stop stress reaction, play the effect of resisting stress, natural Chinese medicinal herb itself is not containing vitamin ingredients, but vitamin function is played, Chinese herbal medicine contains abundant bioactivator, the anti-disease physiological mechanism in body can be regulated, improve the non-specific and specific immune function of livestock and poultry, strengthen the protection capability of body on the whole or there is immunologic enhancement.
The invention provides a kind of feed for improving growth performance of chicks, it comprise corn, wheat bran, the dish dregs of rice, albumen powder, galactomannan, VBT, soybean lecithin, Bee Pollen, salt, sodium bicarbonate, amino acid additive, vitamine supplement, for improving the Chinese herbal feed additive of growth performance of chicks, trace mineral supplement and microorganism formulation.
In described feed, the weight portion of each material composition is respectively corn 80 weight portion ~ 90 weight portion, wheat bran 8 weight portion ~ 12 weight portion, the dish dregs of rice 8 weight portion ~ 12 weight portion, albumen powder 1 weight portion ~ 3 weight portion, galactomannan 2 weight portion ~ 4 weight portion, VBT 1 weight portion ~ 3 weight portion, soybean lecithin 3 weight portion ~ 5 weight portion, Bee Pollen 2 weight portion ~ 4 weight portion, salt 0.5 weight portion ~ 1.5 weight portion, sodium bicarbonate 2 weight portion ~ 4 weight portion, amino acid additive 4 weight portion ~ 6 weight portion, vitamine supplement 4 weight portion ~ 6 weight portion, for improving Chinese herbal feed additive 10 weight portion ~ 15 weight portion of growth performance of chicks, trace mineral supplement 2 weight portion ~ 4 weight portion and microorganism formulation 2 weight portion ~ 4 weight portion.
Further preferably, in described feed, the weight portion of each material composition be respectively corn 85 weight portion, wheat bran 10 weight portion, the dish dregs of rice 10 weight portion, albumen powder 2 weight portion, galactomannan 3 weight portion, VBT 2 weight portion, soybean lecithin 4 weight portion, Bee Pollen 3 weight portion, salt 1 weight portion, sodium bicarbonate 3 weight portion, amino acid additive 5 weight portion, vitamine supplement 5 weight portion, for improving Chinese herbal feed additive 13 weight portion of growth performance of chicks, trace mineral supplement 3 weight portion and microorganism formulation 3 weight portion.
Galactomannans is a kind of biological species animal immunity regulator, has and regulates animal intestinal microorganism, improves animal autoimmunity ability, and prevention animal intestinal disease, improves fertility, improve price of deed power, improve effect of meat.
VBT can growth promoting effects, improves feed conversion rate, improves disease-resistant anti-stress ability, can reduce fat deposition, improves carcass lean meat percentage, improves meat, also can improve fecundity.
Soybean lecithin is the mixture of various phosphoglyceride and derivative thereof in soybean, it is the bioactivator with different physiological roles, mainly comprise lecithin, cephalin, phosphatidylinositols and serinephosphatide, soybean lecithin has the integrality of Cell protection membrane structure and function, anti-oxidant, reducing blood lipid, the effects such as regulation and control fat metabolism, feed intake and the production performance of poultry can be improved, improve the health status of poultry, soybean lecithin adds in mixed feed the dust that can reduce in mixed feed, thus reduce the generation of livestock and birds respiratory disease, the automatic classification of dust from flying and feed can be prevented, to maintenance feed mixture homogeneity, there is good effect, maintain the property balanced in nutrition of daily ration, phosphatide has good lubricity, equipment attrition can be reduced, reduce energy consumption simultaneously, and make the temperature arrising caused by friction of feed reduce to minimum, phospholipid molecule has hydrophilic and oleophylic two groups, therefore phosphatide is good fat emulsifier, the unrighted acid in feed can be protected, improve the Quality and yield of granulating, the consumption of poultry to methionine can be saved, a large amount of liposoluble vitamins is provided, thus the antioxidant levels of fat in feed can be improved.
Bee Pollen contains abundant amino acid, organized enzyme, vitamin, trace element and auxin etc., can supplement and the required nutritional labeling in balanced feed, be conducive to digesting and assimilating of body, growth promoting effects, improve weightening finish, reduce feedstuff-meat ratio.And propolis is similar containing corresponding glue source plant, the concentrate of mass efficient active component, can accelerate the metabolic process of body, promotes growing of body.
Manna oligosaccharide can control micro-ecological environment in intestines and stomach, promote the propagation of beneficial bacterium, suppress the field planting of harmful bacteria, thus maintain normal gut environment, have and adsorb with the Receptor Competition of harmful bacteria, germ is stoped to be combined with animal intestinal epithelial cell, thus acceleration bacterium is discharged from enteron aisle, promote the effect of intestinal microecology balance, there is certain immunogenicity, immune response can be stimulated to react, and can be viral with some, the surface conjunction of toxin and fungal cell is as the adjuvant of these exogenous antigens, and then slow down the absorption of antigen, increase tiring of antigen, promote the glycoprotein of emiocytosis manna oligosaccharide base, these glycoprotein can in conjunction with the bacterium invading human body, trigger the multistage immunologic function of body, and strengthen the protection usefulness of flora, strengthen animal body fluid and cellular immunity.
Microorganism formulation is in the process of fermented feed, and generate on the one hand carbohydrate, amino acids, a large number of nutrients such as protein-based, it directly can increase the nutrition of cultivation body body; On the other hand, enter the dominant population that cultivation body enteron aisle forms useful viable bacteria, the enteric microorganism ecosystem can be improved; Each beneficial bacterium, under good conditions again by a series of biochemical reactions, produces physiological activator.As various digestive ferment, metabolic enzyme, endocrine hormone etc., not only strengthen anti pathologic immunity ability, reduce disease, but also accelerate digesting and assimilating feed nutrient, growth promoting effects, puts on weight, and the price of deed improves.In addition, colony house stink alleviates, environmental sanitary quality improves, also growing up healthy and sound of livestock is conducive to, described microorganism formulation can be Lactobacillus casei, lactobacillus lactis, Lactobacillus plantarum, lactoenterococcus, Pediococcus pentosaceus, saccharomyces cerevisiae, candida utili, swamp Rhodopseudomonas, bacillus subtilis, bacillus licheniformis one or more combine, as source health treasured (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides), this microorganism formulation primary raw material comprises product enzyme bacillus, lactic acid bacteria, saccharomycete, zytase, mannase, glucolase, amylase etc., effective viable bacteria content >=10,000,000,000/gram.
Trace mineral supplement can be the trace mineral supplement of various routine, simple acylate can be used, as ironic citrate, also trace element and amino-acid chelate can be used, as amino acid iron, the trace element added mainly contains iron, zinc, copper, manganese, iodine, cobalt, selenium, molybdenum, also can use composite trace element premix, as Great Britain and America's that Beijing You Libao biotechnology Co., Ltd provides.
Amino acid additive comprises the various conventional amino acid such as serine, glutamic acid, glycine, isoleucine, leucine, alanine, proline, also can adopt amino acid premix, the composite aminophenol powder of as above sea cowry energy Chemical Co., Ltd. production.
Vitamine supplement comprises the various conventional vitamin such as riboflavin, vitamin C, vitamin E, vitamin A, Cobastab, also can adopt vitamin premix, as the excellent dimension element that Beijing You Libao Bioisystech Co., Ltd produces.
Further preferably, described feed is only made up of above-mentioned raw materials.
Chinese veterinarian thinks, The spleen and stomach provide the material basis of the acquired, main muscle and four limbs, be source of generating QI and blood, defeated cloth diet precise and tiny, with nutrition the five internal organs six abdomen four limbs bones of the body collectively, therefore the strong fortune of temper, then diet multiplication, healthy tendency is from filling, nutritional sufficiency, fleshiness is strong, otherwise the contracting of muscle committee, carcass is become thin, therefore, Chinese herbal feed additive provided by the invention is using the theory of Chinese veterinarian's theory of spleen and stomach as guiding theory, by Chinese herbal medicine to reach strengthening the spleen and stomach, aid digestion, thus improve the feed intake of chick, promote the object that absorption of nutrient ingredients is utilized, short to solve chick alimentary canal, the drawback low to efficiency of feed utilization, the bulk drug that described Chinese herbal feed additive comprises has the bighead atractylodes rhizome, spina date seed, mantis egg-case, the vine of multiflower knotweed, Changshan, hawthorn, saline cistanche, radix pseudostellariae, folium panacis japonici cum caule, wilsonii, Chinese yam, the rhizome of davallia, the stem of noble dendrobium, the fruit of glossy privet, asparagus fern, honeysuckle, the fruit of Chinese wolfberry, hairyvein agrimony, the root of herbaceous peony, rhizoma zingiberis, mistletoe, the coptis, great burdock achene, cassia twig, Radix Isatidis, pilose gerbera herb, Virgin's milk mushroom, fokien angiopteris rhizome and water bean cotyledon.
Further, described Chinese herbal feed additive is only made up of above-mentioned raw materials medicine.
The pharmacology of described each bulk drug is as follows:
The bighead atractylodes rhizome: taste is sweet, bitter, warm in nature, enters spleen, stomach warp, has tonifying spleen profit gas, eliminating dampness Li Shui, strengthening exterior and reducing sweat, the effect of moisturizing of fortune spleen, is mainly used in the caused ruffian of the dysfunction of the spleen in transport, QI failing to transform into body fluid and has one's mind filled with and rush down, phlegm and retained fluid oedema; The vexed lazyness speech of the deficiency of qi in middle-jiao, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; The cards such as solid in the playing of deficiency of the spleen causing weakness of QI, abnormal sweating spontaneous perspiration.
Spina date seed: taste is sweet, sour, property is put down, and have nourishing conscience, calm the nerves, effect of arrest sweating, cures mainly restlessness of asrhenia type and insomnia; Palpitation with fear palpitation; The empty card such as spontaneous perspiration, night sweat of body.
Mantis egg-case: latin name OothecaMantidis, becomes sweet, flat, returns liver, kidney, urinary bladder channel, there is kidney tonifying, astringent or styptic treatment for spontaneous sweating, the effect only lost, cure mainly the cards such as the infantile enuresis of the insufficiency of the kidney yang, frequent urination at night, seminal emission premature ejaculation, impotence, not only help but also inducing astrigency, for tonifying the kidney and support yang, controlling nocturnal emission with astringent drugs contracting urine good medicine.The solid caused emission and spermatorrhea of all kidney yang deficiencies, vital essence mistake, the enuresis, frequent micturition, impotence are sterile, all can select, especially should the enuresis, frequent micturition.
The vine of multiflower knotweed: sweet, the micro-hardship of taste, property is put down; The thoughts of returning home, Liver Channel, have effect of energy mental-tranquilization, dispelling wind and removing obstruction in the meridians, cure mainly insomnia and dreamful sleep, deficiency of blood bodily pain, numbness, arthralgia due to wind-dampness, the cards such as wind sore mange.
Changshan: latin name DichroaeRadix, bitter, pungent, cold in nature, return lung, liver, the heart channel of Hang-Shaoyin, there is effect of vomiting phlegmatic savliva, cure mainly phlegm and retained fluid and stop gathering, the cards such as chest diaphragm ruffian plug.
Hawthorn: taste acid, sweet, slightly warm in nature, returns spleen, stomach, Liver Channel, and for food digesting stomach fortifying, promoting the circulation of qi is fallen apart the stasis of blood, and be mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, have loose bowels, dysentery, hawthorn be the staple for the treatment of indigestion, and hawthorn can increase the secretion of peptic digest enzyme, promotes to digest; To shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus etc., there is obvious inhibitory action.
Saline cistanche: taste is sweet, one-tenth, warm in nature, enters kidney, large intestine channel, has kidney-replenishing, benefiting essence-blood, the effect relaxed bowel, for decline of kidney-YANG, the impotence and premature ejaculation of asthenia of essence and blood, infertile, soreness of waist and knee joint, Hiccough and deaf, frequent micturition urine number, the cards such as intestines of the suffering from a deficiency of the kidney deficiency of blood in dry and postpartum, the constipation that body fluid deficiency after being ill.
Radix pseudostellariae: sweet, the micro-hardship of taste, property is put down, and enters spleen, lung channel, has air making-up and spleen enlivening, the effect that moistening lung is promoted the production of body fluid, the few burnout of food for deficiency-weakness of spleen-QI, deficiency of stomach-Yin, the beneficial temper of energy, nourishing stomach-YIN, for the deficiency syndrome of the lung cough caused by dryness of deficiency of vital energy Tianjin wound and palpitaition egersis, abnormal heat sweat many, energy nourishing generate fluid, controls deficiency of vital energy xeropulmonary cough, the card such as palpitaition egersis, hidrosis of deficiency of both qi and yin.
Folium panacis japonici cum caule: bitter, sweet, cold in nature, attach to the lung and stomach meridians, have tonifying Qi, beneficial lung, drives away summer heat, and the effect of promoting the production of body fluid, cures mainly qi-asthenia cough, and hot summer weather is irritated, and Tianjin wound is thirsty, and the head is unclear, and four limbs are tired wearyly waits card.
Wilsonii: latin name AcanthopanacisSenticosiRadixetRhizomaseuCaulis, taste is pungent, bitter, micro-sweet, warm in nature, enter spleen, kidney, the heart channel of Hang-Shaoyin, have and replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, the effect of dispelling rheumatism, soft for wind-cold-dampness arthralgia, lumbocrural pain, muscles and bones impotence, be slow in action, the card such as body void is frail, traumatic injury, fracture, oedema, beriberi, uncontrolled urination are itched.
Chinese yam: taste is sweet, property is put down, enter lung, spleen, kidney channel, have strengthening the spleen and tonifying the lung, beneficial stomach kidney tonifying, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, effect of helping the five internal organs, strengthening the bones and muscles, long will to calm the nerves, promote longevity, cure mainly weakness of the spleen and the stomach, lassitude, poor appetite, chronic diarrhea and dysentery, Lung Qi deficiency are dry, asthma due to excessive phlegm cough, kidney qi loss, soreness and weakness of waist and knees, lower limb impotence are weak, frequent micturition of quenching one's thirst, seminal emission premature ejaculation, band descend the red card such as swollen, fat of gonorrhoea, skin.
The rhizome of davallia: bitter, warm in nature, enter liver, kidney channel, there is nourishing disney and strengthening bone, continuous effect of hindering pain relieving, for soreness of waist and knee joint of suffering from a deficiency of the kidney, flaccidity and weakness of the lower limbs, the deficiency of liver-yin and kidney-yin, empty positive rising and the deafness and tinnitus that causes, tooth mobility pain or bleeding gums, speen-kidney dificiency and cause and rush down the cards such as protracted dysentery for a long time.
The stem of noble dendrobium: cold nature, taste is sweet, returns stomach, kidney channel, has reinforcing stomach reg fluid, nourishing Yin and clearing heat effect.Cure mainly the moon and hinder body fluid deficiency, dry polydipsia, food is few retches, abnormal heat after being ill, and order is secretly not clear waits card.
The fruit of glossy privet: taste is sweet, bitter, is slightly cold, enters liver, kidney channel, has strong liver kidney-nourishing, the effect of removing heat to brighten vision, is mainly used in treating liver-kidney Yin deficiency, and the head loses foster dizzy tinnitus, the symptoms such as yin asthenia generating intrinsic heat.The fruit of glossy privet can promote leucocyte, strengthens effect of immunologic function, has stronger inhibitory action to staphylococcus aureus, shigella dysenteriae.
Asparagus fern: taste is sweet, bitter, cold in nature, returns lung, kidney channel, has nourishing yin to moisten dryness, effect that clearing lung-heat is promoted the production of body fluid, cures mainly cough caused by dryness-heat, and deficiency of Yin labor is coughed, fire excess from yin deficiency, the abscess of throat of the not solid seminal emission of kidney essense, premature ejaculation and flaring up of deficient fire, pyreticosis Tianjin wound is thirsty, and interior heat is quenched one's thirst the cards such as the dry constipation of intestines.
Honeysuckle: taste is sweet, cold in nature, enters the heart, lung, stomach, large intestine channel, has clearing heat and detoxicating effect, doublely can remove heat from the blood and relieve diarrhea.Be mainly used in affection of exogenous wind-heat, the hot poison of warm heat disease is comparatively contained, or when warm disease is still not descending at the part of the body cavity above the diaphragm housing the heart and lungs from the beginning of heat evil; The malicious diarrhea of heat, the lower blood of stool; Heat temperature is demonstrate,proved; The sore carbuncle that hot poison gathers from the beginning of, lift the heat person of swelling and ache etc., honeysuckle has good antipyretic effect, energy anti-inflammatory, what control inflammation oozes out and inflammatory hyperplasia, can leukocytic phagocytic function be promoted, have stronger bacteriostasis to multiple pyococcus and pathogenic entero becteria, comprise staphylococcus, hemolytic streptococcus, diplococcus meningitidis, shigella dysenteriae, typhoid bacillus, Pseudomonas aeruginosa, tubercle bacillus etc., the hot poison that honeysuckle is divided qi and blood battalion is all effective, and has broad-spectrum antibacterial action.
The fruit of Chinese wolfberry: taste is sweet, property is flat, enters liver, kidney channel, have tonify the liver and kidney, nourish blood enrich blood, benefiting shrewd head, the effect that moistens the lung and relieve the cough, be mainly used in liver kidney two void, the soreness and weakness of waist and knees of asthenia of essence and blood, dizziness and tinnitus, seminal emission tinnitus, unconsciously sweat and tire; The impotence of the insufficiency of the kidney yang, sterile; The eyes of deficiency of YIN-essence,impairment of YIN-essence, deficiency of liver-blood dim-sighted and deficiency of Yin labor such as to be coughed at the card, and the fruit of Chinese wolfberry can promote liver cell regeneration, strengthens the effect of non-specific immune function.
Hairyvein agrimony: latin name AgrimoniaeHerba, bitter, puckery, property is put down, the thoughts of returning home, Liver Channel, have astringing to arrest bleeding, only effect of dysentery desinsection, cures mainly various hemorrhage card, such as: haematemesis, hematuria, have blood in stool, uterine bleeding, spitting of blood, bleeding from five sense organs or subcutaneous tissue, dysentery, internal lesion caused by overexertion takes off power, and carbuncle swells, fall and beat, the cards such as traumatic bleeding.
The root of herbaceous peony: latin name PaeoniaeRadixAlba, bitter, acid, cool in nature; enter liver, the spleen channel, there is nourishing blood and liver, pain relieving in slow; astringe yin receives effect of sweat, cures mainly chest abdomen pain over the hypochondriac region, rushes down dysentery stomachache; spontaneous sweating; fever due to yin deficiency, irregular menstruation, uterine bleeding; be with inferior card, the root of herbaceous peony has good liver-protective effect.
Rhizoma zingiberis: taste is pungent, hot in nature, return spleen, stomach, the heart, lung channel; Have warming spleen and stomach for dispelling cold, Hui Yang promotes blood circulation, eliminating dampness dissolving phlegm, effect of warming lung to reduce watery phlegm, and for coldness and pain in the epigastrium, vomiting, have loose bowels, yang depletion is fainted inverse, and cold drink is breathed with cough, the cards such as numbness and ache of cold dampness.
Mistletoe: bitter, sweet, property is put down, and returns liver, kidney channel, has filling liver kidney, strengthening the bones and muscles, wines used as antirheumatic, antiabortive effect, cure mainly soreness of waist and knee joint; Arthralgia due to wind-dampness; Fetal irritability; The card such as blood under threatened abortion.
The coptis: bitter, cold in nature, enter the heart, lung, courage, stomach, large intestine channel, have heat-clearing and damp-drying drug, purging intense heat and detonicating, the effect of cooling blood for improving eyesight, be usually used in the fire for the treatment of removing the heart-fire warp, the dysphoria and insomnia that internal heat is prosperous, and the high fever coma of warm heat disease, the card such as vexed, thirsty.
Great burdock achene: taste is pungent is bitter; Cold in nature, return lung, stomach warp, has dispelling wind and heat from the body, clearing heat and detoxicating promoting eruption, and a surname's lung relieve sore throat falls apart swollen effect, cure mainly anemopyretic cold, warm disease from the beginning of; Wind-heat or cough with lung heat, cough up phlegm not smooth; Abscess of throat; Macula is not saturating; At the measles initial stage, rash goes out not smooth and rubella itch; The card such as sore swollen toxin and mumps.
Cassia twig: taste is pungent, sweet, warm in nature, the thoughts of returning home, lung, urinary bladder channel, there is sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, help yang transforming qi, the effect of eliminating cold to stop pain, cassia twig warming meridians and promoting circulation of qi, horizontal logical podomere, for illness that has not attacked the vital organs of the human body of catching cold, no matter have sweat, losslessly all can to apply, also for arthralgia due to wind-dampness, stomach cold stomachache, through closing, dysmenorrhoea, arthralgia due to wind-dampness, the cards such as shoulder arm podomere crymodynia.
Radix Isatidis: latin name IsatidisRadix, bitter, cold in nature, enter the heart, liver, courage, stomach warp, have the effect of clearing heat and detoxicating, cool blood relieve sore throat, be used for the treatment of febrile virulent maculae; High heat headache; Major part pestilence; Tongue is secretly dark reddish purple, scarlet fever; Erysipelas; Mumps; Larynx numbness; Sore is swollen, carbuncle swells; Varicella; Measles; Hepatitis; Influenza, epidemic meningitis, encephalitis, pneumonia, coma tells nosebleed, and pharynx is swollen, pinkeye, sore rash; Can prevent and treat the cards such as Japanese Type-B encephalitis, acute, chronic hepatitis, mumps, osteomyelitis, Radix Isatidis has inhibitory action to various bacteria. and infusion has inhibitory action in various degree to hay bacillus, staphylococcus aureus, sarcine, Escherichia coli, typhoid bacillus, paratyphosum Bacterium, dysentery (will congratulate, Fu Shi) bacillus, bacillus enteritidis etc.
Pilose gerbera herb: bitter, pungent, property is put down, and have the cough-relieving of a surname's lung, clearing heat and detoxicating, dampness removing, effect of the promoting flow of qi and blood circulation, cures mainly cough due to common cold, and asthma is had loose bowels, dysentery, oedema, stranguria with turbid discharge, epigastric distending pain, treating swelling and pain by traumatic injury, the cards such as venomous snake bite.
Virgin's milk mushroom: bitter, pungent, warm in nature, have expelling wind and clearing away cold, the effect of stimulating the circulation of the blood and cause the muscles and joints to relax, cures mainly lumbocrural pain, numb in every limb, the cards such as muscles and bones is not relaxed, tic of limbs.
Fokien angiopteris rhizome: mildly bitter flavor, cool in nature, have effect of heat-clearing, cool blood, removing toxic substances, cure mainly treating swelling and pain by traumatic injury, traumatism and bleeding, uterine bleeding, acute mastitis, carbuncle swells furunculosis, arthralgia due to wind-dampness, postpartum abdominal pain, vexed insomnia, the cards such as venomous snake bite.
Water bean cotyledon: taste is sweet, light, cool in nature, has clearing heat and promoting diuresis, effect of subdhing swelling and detoxicating, cures mainly dysentery, gonorrhoea, oxyhepatitis, carbuncle sore tumefacting virus, swelling and aching of gum, acute mastitis, acute cerebral meningitis, acute laryngopharyngitis, irregular menstruation, dysmenorrhoea, the cards such as burn and scald.
In described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 35 weight portion ~ 45 weight portion, spina date seed 20 weight portion ~ 30 weight portion, mantis egg-case 25 weight portion ~ 35 weight portion, the vine of multiflower knotweed 30 weight portion ~ 40 weight portion, Changshan 15 weight portion ~ 25 weight portion, hawthorn 30 weight portion ~ 40 weight portion, saline cistanche 35 weight portion ~ 45 weight portion, radix pseudostellariae 40 weight portion ~ 50 weight portion, folium panacis japonici cum caule 30 weight portion ~ 40 weight portion, wilsonii 25 weight portion ~ 35 weight portion, Chinese yam 30 weight portion ~ 40 weight portion, the rhizome of davallia 20 weight portion ~ 30 weight portion, the stem of noble dendrobium 35 weight portion ~ 45 weight portion, the fruit of glossy privet 25 weight portion ~ 35 weight portion, asparagus fern 20 weight portion ~ 30 weight portion, honeysuckle 45 weight portion ~ 55 weight portion, the fruit of Chinese wolfberry 30 weight portion ~ 40 weight portion, hairyvein agrimony 20 weight portion ~ 30 weight portion, the root of herbaceous peony 35 weight portion ~ 45 weight portion, rhizoma zingiberis 15 weight portion ~ 25 weight portion, mistletoe 25 weight portion ~ 35 weight portion, the coptis 55 weight portion ~ 65 weight portion, great burdock achene 20 weight portion ~ 30 weight portion, cassia twig 25 weight portion ~ 35 weight portion, Radix Isatidis 45 weight portion ~ 55 weight portion, pilose gerbera herb 35 weight portion ~ 45 weight portion, Virgin's milk mushroom 20 weight portion ~ 30 weight portion, fokien angiopteris rhizome 25 weight portion ~ 35 weight portion and water bean cotyledon 30 weight portion ~ 40 weight portion.
Further preferably, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 38 weight portion ~ 42 weight portion, spina date seed 23 weight portion ~ 27 weight portion, mantis egg-case 28 weight portion ~ 32 weight portion, the vine of multiflower knotweed 33 weight portion ~ 37 weight portion, Changshan 18 weight portion ~ 22 weight portion, hawthorn 33 weight portion ~ 37 weight portion, saline cistanche 38 weight portion ~ 42 weight portion, radix pseudostellariae 43 weight portion ~ 47 weight portion, folium panacis japonici cum caule 33 weight portion ~ 37 weight portion, wilsonii 28 weight portion ~ 32 weight portion, Chinese yam 33 weight portion ~ 37 weight portion, the rhizome of davallia 23 weight portion ~ 27 weight portion, the stem of noble dendrobium 38 weight portion ~ 42 weight portion, the fruit of glossy privet 28 weight portion ~ 32 weight portion, asparagus fern 23 weight portion ~ 27 weight portion, honeysuckle 48 weight portion ~ 52 weight portion, the fruit of Chinese wolfberry 33 weight portion ~ 37 weight portion, hairyvein agrimony 23 weight portion ~ 27 weight portion, the root of herbaceous peony 38 weight portion ~ 42 weight portion, rhizoma zingiberis 18 weight portion ~ 22 weight portion, mistletoe 28 weight portion ~ 32 weight portion, the coptis 58 weight portion ~ 62 weight portion, great burdock achene 23 weight portion ~ 27 weight portion, cassia twig 28 weight portion ~ 32 weight portion, Radix Isatidis 48 weight portion ~ 52 weight portion, pilose gerbera herb 38 weight portion ~ 42 weight portion, Virgin's milk mushroom 23 weight portion ~ 27 weight portion, fokien angiopteris rhizome 28 weight portion ~ 32 weight portion and water bean cotyledon 33 weight portion ~ 37 weight portion.
Further preferred, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively the bighead atractylodes rhizome 40 weight portion, spina date seed 25 weight portion, mantis egg-case 30 weight portion, the vine of multiflower knotweed 35 weight portion, Changshan 20 weight portion, hawthorn 35 weight portion, saline cistanche 40 weight portion, radix pseudostellariae 45 weight portion, folium panacis japonici cum caule 35 weight portion, wilsonii 30 weight portion, Chinese yam 35 weight portion, the rhizome of davallia 25 weight portion, the stem of noble dendrobium 40 weight portion, the fruit of glossy privet 30 weight portion, asparagus fern 25 weight portion, honeysuckle 50 weight portion, the fruit of Chinese wolfberry 35 weight portion, hairyvein agrimony 25 weight portion, the root of herbaceous peony 40 weight portion, rhizoma zingiberis 20 weight portion, mistletoe 30 weight portion, the coptis 60 weight portion, great burdock achene 25 weight portion, cassia twig 30 weight portion, Radix Isatidis 50 weight portion, pilose gerbera herb 40 weight portion, Virgin's milk mushroom 25 weight portion, fokien angiopteris rhizome 30 weight portion and water bean cotyledon 35 weight portion.
Present invention also offers the preparation method of above-mentioned Chinese herbal feed additive, be specially:
Above-mentioned raw materials medicine component is mixed by weight, obtains mixture, put into reactor, add the water relative to mixture quality 3 ~ 5 times, slow fire heating decoction 2 ~ 4 hours, decoction liquor is filtered, filter residue adds the water relative to the mixture quality obtained 2 ~ 4 times above, again slow fire boiling 1 ~ 3 hour, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
Present invention also offers the preparation method of above-mentioned feed, it comprises:
The first step, get 3kg microbe additive to join in 50kg ~ 100kg water and mix, obtain zymotic fluid, 85kg corn, 10kg wheat bran, the 10kg dish dregs of rice are mixed, obtain mixture, getting the zymotic fluid that 100kg obtains above joins in the mixture obtained above, and evenly pack is closed, and is placed in the environment of 20 DEG C ~ 30 DEG C and obtains fermentation material after 10 ~ 20 days;
Second step, prepares Chinese herbal feed additive according to the method described above;
3rd step, fodder mixing machine is put into together with the Chinese herbal feed additive that the fermentation material first step obtained and second step obtain and other components, continuous uniform stirs after 1 ~ 3 hour, put into pulverizer tentatively to pulverize, putting into micronizer after taking-up again, to carry out separating twice be fine grained, and the fine grained after pulverizing gets product feed after sterilization, sealing, pack.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine composition feed addictive 1
By bighead atractylodes rhizome 40g, spina date seed 25g, mantis egg-case 30g, vine of multiflower knotweed 35g, Changshan 20g, hawthorn 35g, saline cistanche 40g, radix pseudostellariae 45g, folium panacis japonici cum caule 35g, wilsonii 30g, Chinese yam 35g, rhizome of davallia 25g, stem of noble dendrobium 40g, fruit of glossy privet 30g, asparagus fern 25g, honeysuckle 50g, fruit of Chinese wolfberry 35g, hairyvein agrimony 25g, root of herbaceous peony 40g, rhizoma zingiberis 20g, mistletoe 30g, coptis 60g, great burdock achene 25g, cassia twig 30g, Radix Isatidis 50g, pilose gerbera herb 40g, Virgin's milk mushroom 25g, fokien angiopteris rhizome 30g and water bean cotyledon 35g mixes, obtain mixture, put into reactor, add the water of 4kg, slow fire heating decoction 3 hours, decoction liquor is filtered, filter residue adds the water of 3kg, slow fire boiling 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 1.
Embodiment 2 Chinese medicine composition feed addictive 2
By bighead atractylodes rhizome 38g, spina date seed 23g, mantis egg-case 28g, vine of multiflower knotweed 33g, Changshan 18g, hawthorn 33g, saline cistanche 38g, radix pseudostellariae 43g, folium panacis japonici cum caule 33g, wilsonii 28g, Chinese yam 33g, rhizome of davallia 23g, stem of noble dendrobium 38g, fruit of glossy privet 28g, asparagus fern 23g, honeysuckle 48g, fruit of Chinese wolfberry 33g, hairyvein agrimony 23g, root of herbaceous peony 38g, rhizoma zingiberis 18g, mistletoe 28g, coptis 58g, great burdock achene 23g, cassia twig 28g, Radix Isatidis 48g, pilose gerbera herb 38g, Virgin's milk mushroom 23g, fokien angiopteris rhizome 28g and water bean cotyledon 33g mixes, obtain mixture, put into reactor, add the water of 3.5kg, slow fire heating decoction 3 hours, decoction liquor is filtered, filter residue adds the water of 2.5kg, slow fire boiling 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 2.
Embodiment 3 Chinese medicine composition feed addictive 3
By bighead atractylodes rhizome 42g, spina date seed 27g, mantis egg-case 32g, vine of multiflower knotweed 37g, Changshan 22g, hawthorn 37g, saline cistanche 42g, radix pseudostellariae 47g, folium panacis japonici cum caule 37g, wilsonii 32g, Chinese yam 37g, rhizome of davallia 27g, stem of noble dendrobium 42g, fruit of glossy privet 32g, asparagus fern 27g, honeysuckle 52g, fruit of Chinese wolfberry 37g, hairyvein agrimony 27g, root of herbaceous peony 42g, rhizoma zingiberis 22g, mistletoe 32g, coptis 62g, great burdock achene 27g, cassia twig 32g, Radix Isatidis 52g, pilose gerbera herb 42g, Virgin's milk mushroom 27g, fokien angiopteris rhizome 32g and water bean cotyledon 37g mixes, obtain mixture, put into reactor, add the water of 4kg, slow fire heating decoction 3 hours, decoction liquor is filtered, filter residue adds the water of 3kg, slow fire boiling 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 3.
Embodiment 4 pharmacological toxicity is tested
Acute toxicity test data
Detect reagent
Serum AST, ALT detection kit are purchased from Rui Sheng bio tech ltd, Qingdao.
Checkout equipment
Micro-200 semiautomatic biochemistry detector, assay balance, disscting instrument, syringe, test tube etc.
Test method
After the adaptability of 3 days are raised, be divided at random 4 groups (male and female half and half), often organize each 20; Control group, 3 different pharmaceutical groups (are respectively 300g/kg body weight, 240g/kg body weight, 180g/kg body weight), control group gavage physiological saline, the Chinese herbal feed additive 1 of 3 the medicine group gavage embodiment of the present invention 1 preparations, is dissolved in Chinese herbal feed additive in water and gavages mouse.
Testing index and method
(1) clinicing symptom observation: every day viewing test mouse the state of mind, diet situation, every day entry morbidity death condition.
(2) pathological observation: dead mouse is carried out cuing open inspection and observes internal organ change.
(3) growth indexes is observed: carry out routine weighing to test mouse; Off-test, slaughters that mouse weighs in, the heavy organ index of internal organs measures: cut open inspection rat, core dirty, spleen, liver, kidney, testis, ovary, weigh, calculate organ index according to the following formula: organ index=internal organs weight/body weight × 100.
(4) liver function change is observed: after off-test, slaughter mouse, take blood separation of serum, measures AST, ALT.
Data process&analysis
Each group of data all use mean soil standard deviation represent, each group mean does test of normality and duplicate measurements homogeneity test of variance, with inspection younger between one-way analysis of variance group), P < 0.05 is for differing significantly, and P < 0.01 is difference highly significant.Statistical computation all adopts SPSS12.0 software to complete.
Clinicing symptom observation
Control group and test group mouse, the state of mind and diet wish, to external world respond have no obvious exception.Each group of mouse morbidity and death condition are as following table 1.
Table 1
Grouping Sum Dead (only) The death rate (%)
1(300g/kg) 20 0 0
2(240g/kg) 20 0 0
3(120g/kg) 20 0 0
Control group 20 0 0
Pathological observation: control group and test group, mouse carries out cuing open inspection and observes to have no and observe the obvious pathological change of internal organs after slaughtering.
Growth indexes is observed: off-test, slaughters that mouse weighs in, internal organs weight analysis is in table 2.
Table 2
Grouping Liver index Cardiac index Renal index Lungs index Index and spleen index
1(300g/kg) 5.83±0.26 0.76±0.05 1.29±0.21 0.63±0.02 0.52±0.03
2(240g/kg) 5.79±0.31 0.78±0.03 1.27±0.16 0.67±0.06 0.53±0.05
3(120g/kg) 5.80±0.22 0.72±0.07 1.23±0.13 0.69±0.03 0.49±0.03
Control group 5.70±0.31 0.79±0.06 1.30±0.17 0.69±0.11 0.53±0.07
Liver function change is observed
After off-test, slaughter mouse, take blood separation of serum, measure AST (glutamic-oxalacetic transaminease), ALT (glutamic-pyruvic transaminase) in table 3.It is not remarkable that result shows each group of data difference compared with normal healthy controls group, is all in normal range (NR).
Table 3
Grouping Sum ALT AST
1(300g/kg) 20 34.16±2.53 131.73±13.91
2(240g/kg) 20 33.29±2.62 133.21±10.75
3(120g/kg) 20 33.73±2.59 132.63±9.38
Control group 20 35.11±3.26 131.26±14.11
Long term toxicity test data
Chinese herbal feed additive 10g/kg, 20g/kg, 100g/kg of the present invention of preparing according to embodiment 1 were to the continuous gastric infusion of rat 3 months, the fur of animal, the colour of skin, ingest, activity, the blood parameters such as routine blood test, Liver and kidney function of the animal all without exception such as urine, feces and animal main organs index all in normal range (NR), and normal kinetic indifference histopathologic examination shows, the important organs such as the heart, liver, spleen, lung, kidney, adrenal gland, tracheae, testis, ovary are without pathological change.Drug withdrawal checks above indices all without overt toxicity reaction after two weeks, show without cumulative toxicity.
Embodiment 5 feed 1
Get 3kg microbe additive source health treasured (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides) to join in 100kg water and mix, obtain zymotic fluid, the zymotic fluid that 100kg obtains is joined corn 85kg, wheat bran 10kg, in the main feed composition that dish dregs of rice 10kg is formed, even pack is closed, be placed in the environment of 25 DEG C and obtain fermentation material after 15 days, the Chinese herbal feed additive 13kg that the fermentation material of acquisition and embodiment 1 are obtained and galactomannan (rural area, Zhengzhou food science and technology Co., Ltd provides) 3kg, VBT (Zhengzhou Cheng Wang chemical industry Co., Ltd provides) 2kg, soybean lecithin (the magnificent phosphatide Science and Technology Ltd. in source, Beijing provides) 4kg, Bee Pollen (Guangzhou Tan Shan apiculture Co., Ltd provides) 3kg, salt 1kg, sodium bicarbonate 3kg, amino acid additive composite aminophenol powder (upper sea cowry energy Chemical Co., Ltd. produces) 5kg, the excellent dimension element of vitamine supplement (production of Beijing You Libao Bioisystech Co., Ltd) 5kg, trace mineral supplement Great Britain and America that (Beijing You Libao biotechnology Co., Ltd provides) 3kg puts into fodder mixing machine together, after continuous uniform stirs 3 hours, put into pulverizer tentatively to pulverize, putting into micronizer after taking-up again, to carry out separating twice be fine grained, fine grained after pulverizing is through sterilization, sealing, get product after pack feed 1.
Comparative example
Get 3kg microbe additive source health treasured (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides) to join in 100kg water and mix, obtain zymotic fluid, the zymotic fluid that 100kg obtains is joined corn 85kg, wheat bran 10kg, in the main feed composition that dish dregs of rice 10kg is formed, even pack is closed, be placed in the environment of 25 DEG C and obtain fermentation material after 15 days, by the fermentation material of acquisition and galactomannan (rural area, Zhengzhou food science and technology Co., Ltd provides) 3kg, VBT (Zhengzhou Cheng Wang chemical industry Co., Ltd provides) 2kg, soybean lecithin (the magnificent phosphatide Science and Technology Ltd. in source, Beijing provides) 4kg, Bee Pollen (Guangzhou Tan Shan apiculture Co., Ltd provides) 3kg, salt 1kg, sodium bicarbonate 3kg, amino acid additive composite aminophenol powder (upper sea cowry energy Chemical Co., Ltd. produces) 5kg, the excellent dimension element of vitamine supplement (production of Beijing You Libao Bioisystech Co., Ltd) 5kg, trace mineral supplement Great Britain and America that (Beijing You Libao biotechnology Co., Ltd provides) 3kg puts into fodder mixing machine together, after continuous uniform stirs 3 hours, put into pulverizer tentatively to pulverize, putting into micronizer after taking-up again, to carry out separating twice be fine grained, fine grained after pulverizing is through sterilization, sealing, get product after pack feed 2.
Embodiment 6 effect data
Test feed
The feed 1 that test group adopts embodiment 5 to prepare, the feed 2 that control group adopts comparative example to be prepared into.
Experimental animal and feeding and management
Healthy 1 age in days AA chick 800 is selected in test, is divided into test group and control group, often organizes 4 repetitions, each repetition 100 chickens, and the feed 1 of test group feeding embodiment 5 preparation, the feed 2 that control group feeding comparative example is prepared into, experimental period is 48 days.
Feeding and management
Test chicken is flat on the net supports, and respectively organize fence every 15d in recurrence interval in interval and group and adjust 1 time, timing feeding, freely drink water, regular vaccine injection, adopt four groups of fans to carry out giving up interior ventilation, hen house ight soil is disposable removing when delivering for sale.Control group adds antibiotics chemicals in right amount according to production actual conditions, or drinking-water or be mixed into feed and take; Test group chicken does not adopt antibiotics chemicals to carry out prevention from suffering from the diseases.
To weigh before 6:30 each group of every day the feed feed intake day before yesterday, weekly the 1st day early 7:00 carry out empty stomach and weigh.Conscientiously observe chicken public sentiment condition in experimental period, record is dead washes in a pan chicken number and medicining condition.After off-test, often organize chicken and randomly draw 10, put in isolated column, carry out slaughter determining after 24h on an empty stomach.
Observation index
Production performance index
Body Mass Index: in experimental period, early 7:00 was front in the 1st day weekly carries out measured body weight to all chickens in group, take g as body weight measurement unit.
Feed daily ingestion amount index: early 7:00 respectively organized chicken feed total amount of searching for food to front 1d before not feeding intake and weighed every day, took kg as daily ingestion amount measurement unit.
Death condition index
Every day early the dead quantity of chicken in record group before 6:30, cut open inspection pathology or the cause of disease.
Slaughter index
Slaughter traits
Jugular vein bloodletting is butchered, and wet method pulls out plumage, slaughter traits=live body weight-blood weight-feather weight, unit g.
Half clean thorax weight
Open abdomen and remove internal organ (comprising esophagus, prolixity capsule, tracheae, reproductive system and digestive system), stay the weight after kidney, lung, heart, liver (removing courage) and muscular stomach (removing inclusion cutin membrane), unit g.
Complete clean thorax weight
Half clean thorax heavily removes the body weight after head, pin, heart, liver, muscular stomach, unit g.
Abdomen fat weight
Weigh around trunk belly leaf fat, muscular stomach and the fat weight at nearly anus place, unit g.
Data process&analysis
Each group of data all use mean soil standard deviation represent, each group mean does test of normality and duplicate measurements homogeneity test of variance, with inspection younger between one-way analysis of variance group), P < 0.05 is for differing significantly, and P < 0.01 is difference highly significant.Statistical computation all adopts SPSS12.0 software to complete.
Result
Chinese herbal feed additive, on the impact of chick production performance, the results are shown in Table 4.
Table 4 Chinese herbal feed additive is on the impact of chick production performance
Time Index Test group Control group
Weightening finish in phase 329.00±3.24 327.91±1.50
1 ~ 14 age in days Feed intake in phase 529.03±4.93 536.43±5.61
Feed-weight ratio 1.61∶1 1.64∶1
Weightening finish in phase 1351.39±13.39 1267.88±18.35
15 ~ 35 ages in days Feed intake in phase 2601.49±14.06 2602.65±12.87
Feed-weight ratio 1.93∶1 2.05∶1
Weightening finish in phase 1275.10±27.93 1258.87±26.23
36 ~ 48 ages in days Feed intake in phase 2726.73±21.57 2779.20±28.61
Feed-weight ratio 2.14∶1 2.21∶1
Weightening finish in phase 2955.49±33.75 2854.67±39.33
1 ~ 48 age in days Feed intake in phase 5857.25±26.29 5918.29±28.19
Feed-weight ratio 1.98∶1 2.07∶1
From table 4 result of the test, test group weightening finish is higher than control group (P < 0.05), test group weightening finish more than control group 100.82g, improve 3.53%, test group feed intake reduces 61.04g than control group, significant difference, P < 0.05, from feed-weight ratio index, test group reduces by 4.35% than control group.
Chinese herbal feed additive, on the impact of the chick death rate, the results are shown in Table 5.
Table 5 Chinese herbal feed additive is on the impact of the chick death rate
Control group Test group
First week 0.25% (1 plumage) 0.25% (1 plumage)
Second week 1.00% (4 plumage) 0.25% (1 plumage)
3rd week 0.50% (2 plumage) 0.00% (0 plumage)
4th week 1.00% (4 plumage) 0.75% (3 plumage)
5th week 1.75% (7 plumage) 1.25% (5 plumage)
6th week 1.50% (6 plumage) 0.75% (3 plumage)
7th week 1.75% (7 plumage) 1.00% (4 plumage)
Quan Qi 7.75% (31 plumage) 4.25% (17 plumage)
As can be seen from Table 5, adopt the chick death rate of Chinese herbal feed additive provided by the invention significantly lower than control group.
Chinese herbal feed additive compares chick Slaughter, the results are shown in Table 6.
Table 6 Chinese herbal feed additive compares chick Slaughter
Project Control group Test group
Complete clean thorax dressing percentage 67.13±0.91 70.13±0.77
Half clean thorax dressing percentage 81.42±1.14 83.05±2.11
Abdominal fat 1.92±0.23 1.77±0.08
As can be seen from Table 6, the Slaughter of the chick of Chinese herbal feed additive of the present invention is adopted significantly to be better than control group, P < 0.05.
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (5)

1. for improving a feed for growth performance of chicks, be made up of following raw material: corn, wheat bran, the dish dregs of rice, albumen powder, galactomannan, VBT, soybean lecithin, Bee Pollen, salt, sodium bicarbonate, amino acid additive, vitamine supplement, for improving the Chinese herbal feed additive of growth performance of chicks, trace mineral supplement and microorganism formulation;
The weight portion of each material composition is respectively corn 80 weight portion ~ 90 weight portion, wheat bran 8 weight portion ~ 12 weight portion, the dish dregs of rice 8 weight portion ~ 12 weight portion, albumen powder 1 weight portion ~ 3 weight portion, galactomannan 2 weight portion ~ 4 weight portion, VBT 1 weight portion ~ 3 weight portion, soybean lecithin 3 weight portion ~ 5 weight portion, Bee Pollen 2 weight portion ~ 4 weight portion, salt 0.5 weight portion ~ 1.5 weight portion, sodium bicarbonate 2 weight portion ~ 4 weight portion, amino acid additive 4 weight portion ~ 6 weight portion, vitamine supplement 4 weight portion ~ 6 weight portion, for improving Chinese herbal feed additive 10 weight portion ~ 15 weight portion of growth performance of chicks, trace mineral supplement 2 weight portion ~ 4 weight portion and microorganism formulation 2 weight portion ~ 4 weight portion,
The bulk drug of described Chinese herbal feed additive is made up of the bighead atractylodes rhizome, spina date seed, mantis egg-case, the vine of multiflower knotweed, Changshan, hawthorn, saline cistanche, radix pseudostellariae, folium panacis japonici cum caule, wilsonii, Chinese yam, the rhizome of davallia, the stem of noble dendrobium, the fruit of glossy privet, asparagus fern, honeysuckle, the fruit of Chinese wolfberry, hairyvein agrimony, the root of herbaceous peony, rhizoma zingiberis, mistletoe, the coptis, great burdock achene, cassia twig, Radix Isatidis, pilose gerbera herb, Virgin's milk mushroom, fokien angiopteris rhizome and water bean cotyledon;
In described Chinese herbal feed additive, the weight proportion of each bulk drug is respectively the bighead atractylodes rhizome 35 ~ 45, spina date seed 20 ~ 30, mantis egg-case 25 ~ 35, the vine of multiflower knotweed 30 ~ 40, Changshan 15 ~ 25, hawthorn 30 ~ 40, saline cistanche 35 ~ 45, radix pseudostellariae 40 ~ 50, folium panacis japonici cum caule 30 ~ 40, wilsonii 25 ~ 35, Chinese yam 30 ~ 40, the rhizome of davallia 20 ~ 30, the stem of noble dendrobium 35 ~ 45, the fruit of glossy privet 25 ~ 35, asparagus fern 20 ~ 30, honeysuckle 45 ~ 55, the fruit of Chinese wolfberry 30 ~ 40, hairyvein agrimony 20 ~ 30, the root of herbaceous peony 35 ~ 45, rhizoma zingiberis 15 ~ 25, mistletoe 25 ~ 35, the coptis 55 ~ 65, great burdock achene 20 ~ 30, cassia twig 25 ~ 35, Radix Isatidis 45 ~ 55, pilose gerbera herb 35 ~ 45, Virgin's milk mushroom 20 ~ 30, fokien angiopteris rhizome 25 ~ 35 and water bean cotyledon 30 ~ 40.
2. feed as claimed in claim 1, it is characterized in that: the preparation method of described Chinese herbal feed additive, be specially and described bulk drug component is mixed by weight, obtain mixture, put into reactor, add the water relative to mixture quality 3 ~ 5 times, slow fire heating decoction 2 ~ 4 hours, decoction liquor is filtered, filter residue adds the water relative to the mixture quality obtained 2 ~ 4 times above, again slow fire boiling 1 ~ 3 hour, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
3. the preparation method of the feed described in claim 1 or 2, is characterized in that, comprising:
The first step, get 3kg microorganism formulation to join in 100kg water and mix, obtain zymotic fluid, 85kg corn, 10kg wheat bran, the 10kg dish dregs of rice are mixed, obtain mixture, getting the zymotic fluid that 100kg obtains above joins in the mixture obtained above, and evenly pack is closed, and is placed in the environment of 20 DEG C ~ 30 DEG C and obtains fermentation material after 10 ~ 20 days;
Second step, prepares Chinese herbal feed additive according to the method described above;
3rd step, fodder mixing machine is put into together with the Chinese herbal feed additive that the fermentation material first step obtained and second step obtain and other components, continuous uniform stirs after 1 ~ 3 hour, put into pulverizer tentatively to pulverize, putting into micronizer after taking-up again, to carry out separating twice be fine grained, and the fine grained after pulverizing gets product feed after sterilization, sealing, pack.
4. for improving a Chinese herbal feed additive for growth performance of chicks, it is characterized in that: bulk drug is made up of the bighead atractylodes rhizome, spina date seed, mantis egg-case, the vine of multiflower knotweed, Changshan, hawthorn, saline cistanche, radix pseudostellariae, folium panacis japonici cum caule, wilsonii, Chinese yam, the rhizome of davallia, the stem of noble dendrobium, the fruit of glossy privet, asparagus fern, honeysuckle, the fruit of Chinese wolfberry, hairyvein agrimony, the root of herbaceous peony, rhizoma zingiberis, mistletoe, the coptis, great burdock achene, cassia twig, Radix Isatidis, pilose gerbera herb, Virgin's milk mushroom, fokien angiopteris rhizome and water bean cotyledon;
The weight portion of each bulk drug is respectively the bighead atractylodes rhizome 35 weight portion ~ 45 weight portion, spina date seed 20 weight portion ~ 30 weight portion, mantis egg-case 25 weight portion ~ 35 weight portion, the vine of multiflower knotweed 30 weight portion ~ 40 weight portion, Changshan 15 weight portion ~ 25 weight portion, hawthorn 30 weight portion ~ 40 weight portion, saline cistanche 35 weight portion ~ 45 weight portion, radix pseudostellariae 40 weight portion ~ 50 weight portion, folium panacis japonici cum caule 30 weight portion ~ 40 weight portion, wilsonii 25 weight portion ~ 35 weight portion, Chinese yam 30 weight portion ~ 40 weight portion, the rhizome of davallia 20 weight portion ~ 30 weight portion, the stem of noble dendrobium 35 weight portion ~ 45 weight portion, the fruit of glossy privet 25 weight portion ~ 35 weight portion, asparagus fern 20 weight portion ~ 30 weight portion, honeysuckle 45 weight portion ~ 55 weight portion, the fruit of Chinese wolfberry 30 weight portion ~ 40 weight portion, hairyvein agrimony 20 weight portion ~ 30 weight portion, the root of herbaceous peony 35 weight portion ~ 45 weight portion, rhizoma zingiberis 15 weight portion ~ 25 weight portion, mistletoe 25 weight portion ~ 35 weight portion, the coptis 55 weight portion ~ 65 weight portion, great burdock achene 20 weight portion ~ 30 weight portion, cassia twig 25 weight portion ~ 35 weight portion, Radix Isatidis 45 weight portion ~ 55 weight portion, pilose gerbera herb 35 weight portion ~ 45 weight portion, Virgin's milk mushroom 20 weight portion ~ 30 weight portion, fokien angiopteris rhizome 25 weight portion ~ 35 weight portion and water bean cotyledon 30 weight portion ~ 40 weight portion.
5. the preparation method of Chinese herbal feed additive according to claim 4, is characterized in that:
Above-mentioned raw materials medicine component is mixed by weight, obtains mixture, put into reactor, add the water relative to mixture quality 3 ~ 5 times, slow fire heating decoction 2 ~ 4 hours, decoction liquor is filtered, filter residue adds the water relative to the mixture quality obtained 2 ~ 4 times above, again slow fire boiling 1 ~ 3 hour, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
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CN104082569A (en) * 2014-06-11 2014-10-08 马鞍山市五谷禽业专业合作社 Formula of chicken feed for improving smooth and tender degree of meat and preparation method thereof
CN104905009A (en) * 2015-06-29 2015-09-16 胡凡营 Plant source feed additive based on environment-friendly feeding of livestock and poultry
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CN105639111A (en) * 2016-01-12 2016-06-08 中国农业科学院特产研究所 Formula of Chinese medicinal herb additive capable of effectively preventing and treating nest separation stress of minks, foxes and racoon dogs, and preparation method of Chinese medicinal herb additive
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