CN109195971B - 抗微生物化合物 - Google Patents

抗微生物化合物 Download PDF

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Publication number
CN109195971B
CN109195971B CN201780024990.4A CN201780024990A CN109195971B CN 109195971 B CN109195971 B CN 109195971B CN 201780024990 A CN201780024990 A CN 201780024990A CN 109195971 B CN109195971 B CN 109195971B
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compound
bacteria
bacterium
culture
bacterial
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Chinese (zh)
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CN109195971A (zh
Inventor
哈佛·斯莱塔
克里斯汀·弗洛格斯塔特·德吉斯
特龙·埃尔林·埃林森
安娜·努德堡
盖尔·克林肯伯格
西格丽德·哈瓦格
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Sinvent AS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN201780024990.4A 2016-04-22 2017-04-21 抗微生物化合物 Active CN109195971B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20160680A NO341815B1 (en) 2016-04-22 2016-04-22 New antimicrobial compound, a method of producing it, pharmaceutical compositions and uses in therapy
NO20160680 2016-04-22
PCT/EP2017/059521 WO2017182632A1 (en) 2016-04-22 2017-04-21 New antimicrobial compound

Publications (2)

Publication Number Publication Date
CN109195971A CN109195971A (zh) 2019-01-11
CN109195971B true CN109195971B (zh) 2021-08-27

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Family Applications (1)

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CN201780024990.4A Active CN109195971B (zh) 2016-04-22 2017-04-21 抗微生物化合物

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US (1) US10494375B2 (enExample)
EP (1) EP3445766B1 (enExample)
JP (1) JP6964600B2 (enExample)
CN (1) CN109195971B (enExample)
DK (1) DK3445766T3 (enExample)
ES (1) ES2909248T3 (enExample)
HR (1) HRP20220350T1 (enExample)
NO (1) NO341815B1 (enExample)
PL (1) PL3445766T3 (enExample)
PT (1) PT3445766T (enExample)
WO (1) WO2017182632A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109280692A (zh) * 2018-10-31 2019-01-29 广东药科大学 一种蜚蠊内生放线菌的抗真菌活性筛选方法及其发酵方法
KR102112570B1 (ko) * 2019-01-28 2020-05-19 한국해양과학기술원 신규 람노리피드 화합물 및 이의 용도
CN109956951B (zh) * 2019-04-11 2021-01-01 中国医学科学院医药生物技术研究所 鹿色霉素(cervinomycin)C1、C2、C3、C4及其生产方法及应用
CN120478324A (zh) * 2025-04-28 2025-08-15 暨南大学 泛酸或其药学上可接受的盐在制备增强病原菌对达托霉素的敏感性的药物中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494913A (en) * 1994-12-13 1996-02-27 Schering Corporation Antifungal compounds
WO2007079715A2 (de) * 2006-01-09 2007-07-19 Merlion Pharmaceuticals Gmbh Neue lysolipin derivate
WO2007095696A1 (en) * 2006-02-27 2007-08-30 The University Of Queensland Polyketide xanthones and uses thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494913A (en) * 1994-12-13 1996-02-27 Schering Corporation Antifungal compounds
WO2007079715A2 (de) * 2006-01-09 2007-07-19 Merlion Pharmaceuticals Gmbh Neue lysolipin derivate
WO2007095696A1 (en) * 2006-02-27 2007-08-30 The University Of Queensland Polyketide xanthones and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
A New Potent Antifungal Agent from Actinoplanes sp.;Min Chu et al.;《Tetrahedron Letters》;19981231;第39卷;第7649-7652页 *
Polycyclic xanthone natural products: structure,biological activity and chemical synthesis;Dana K. Winter et al.;《Nat.Prod.Rep.》;20131231;第30卷;第382-391页 *
链霉菌属微生物来源的生物活性天然产物;傅俊曾等;《Drug Evaluation Research》;20100430;第33卷(第2期);第153-158页 *

Also Published As

Publication number Publication date
PT3445766T (pt) 2022-03-21
US20190135822A1 (en) 2019-05-09
JP2019521078A (ja) 2019-07-25
HRP20220350T1 (hr) 2022-05-13
US10494375B2 (en) 2019-12-03
ES2909248T3 (es) 2022-05-05
CN109195971A (zh) 2019-01-11
NO20160680A1 (en) 2017-10-23
DK3445766T3 (da) 2022-03-21
PL3445766T3 (pl) 2022-04-04
EP3445766B1 (en) 2021-12-15
EP3445766A1 (en) 2019-02-27
JP6964600B2 (ja) 2021-11-10
WO2017182632A1 (en) 2017-10-26
NO341815B1 (en) 2018-01-29

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