CN109173091A - It is a kind of easily from the Inner irradiation device taken out in vivo - Google Patents

It is a kind of easily from the Inner irradiation device taken out in vivo Download PDF

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Publication number
CN109173091A
CN109173091A CN201811113548.1A CN201811113548A CN109173091A CN 109173091 A CN109173091 A CN 109173091A CN 201811113548 A CN201811113548 A CN 201811113548A CN 109173091 A CN109173091 A CN 109173091A
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CN
China
Prior art keywords
medical
hole
medical material
alloy
type glue
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Pending
Application number
CN201811113548.1A
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Chinese (zh)
Inventor
阎尔坤
白红升
白鹏飞
王玉珂
黄泾清
贾通
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Tianjin Co Ltd Of Saden Medicine Research Academy
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Tianjin Co Ltd Of Saden Medicine Research Academy
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Priority to CN201811113548.1A priority Critical patent/CN109173091A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention discloses a kind of easily from the Inner irradiation device taken out in vivo, including medical material silk, fluted or hole is arranged on medical material silk, radioactive source is connect by medical adhesive with groove or hole.The invention has the benefit that easy to operate, operating time is short;It realizes accurate positioning of the radioactive source in tumour, avoids the variation for influencing source positions because of organ activity;Falling off or migrating for radioactive source is avoided, side effect, good effect are reduced;After treatment, taking-up radioactive source can be facilitated, noresidue reduces the unnecessary irradiation of normal tissue, reduces side reaction;It keeps organ complete and function perfects.

Description

It is a kind of easily from the Inner irradiation device taken out in vivo
Technical field
The invention belongs to the field of medical instrument technology, are related to one kind easily from the Inner irradiation device taken out in vivo.
Background technique
Malignant tumour, which has become, a kind of seriously threatens human health and common multiple disease.Currently, radiotherapy becomes One of the three big main means for treating tumour.When radiotherapy mainly penetrates tissue using ray, normal tissue and tumour Cell controls difference biological respinse mechanism caused by radioactive ray the growth and proliferation for the treatment of tumour cell.With operative treatment It is compared with chemotherapy, radiotherapy can retain the function of treated organ, and treatment side effect is small, can effectively ensure that patient is cured Life quality afterwards.
Radioactive prospecting instrument tumour is subjected to internal radiotherapy, also known as brachytherapy is percutaneous or art in lead to Implant needle or implanting device are crossed by a certain number of radioactive source implantation tumours position, the ray issued using radioactive source is for a long time to swollen The irradiation of oncocyte, killing or kill tumour cell, to achieve the purpose that treatment.The treatment technology is widely using various The implanted treatment of entity tumor, achieves good therapeutic effect.It is excellent that this method has that curative effect is high, easy to operate and wound is small etc. Point.But there is also some disadvantages for this method (radioactivity Implantation in Treating), as influenced after (1) implantation because of organ activity Source positions and arrangement cause dosage distribution to change, influence therapeutic effect;(2) falling off or migrate there are radioactive source;(3) Radioactive source stays in the body, and is not easily taken out after treatment, to patient at heart or body brings certain burden;(4) clinical manipulation phase To complexity, operating time is long.These disadvantages, what is showed in the treatment of head and neck neoplasm, superficial tumor and breast cancer etc. is brighter It is aobvious.
Summary of the invention
The purpose of the present invention is overcoming the prior art, one kind is provided and is mainly used for treating hand, foot, ear, tongue, nose The shallower tumour such as chamber, incidence, mammary gland, easy to operate, structure is simple, good effect, easily from the Inner irradiation device taken out in vivo.
A second object of the present invention is to provide another kind be mainly used for treat hand, foot, ear, tongue, nasal cavity, incidence, The shallower tumour such as mammary gland, easy to operate, structure is simple, good effect, easily from the Inner irradiation device taken out in vivo.
Technical solution of the present invention is summarized as follows:
It is a kind of easily from the Inner irradiation device taken out in vivo, including medical material silk 1, be provided on medical material silk 1 recessed Slot 2 or hole 3, radioactive source 4 are connect by medical adhesive 5 with groove 2 or hole 3.
The diameter of medical material silk 1 is 0.3mm~2mm, and length is 10mm~1000mm.
Medical material is gold, silver, platinum, tantalum, niobium, zirconium, medical stainless steel, medical titanium, medical titanium alloy, Co-Cr-Mo conjunction Gold, gathers Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, polyether-polyurethane, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon Methyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable seam Zygonema;The medical adhesive 5 is medical p-type glue, medical EC type glue, medical inosculating type glue, medical ZT type glue or bone cement.
The number in groove 2 or hole 3 is 1-15.
The both ends of medical material silk 1 and fixing clamp, snak link or button 6 are flexibly connected.
Second easily from the Inner irradiation device taken out in vivo, including medical material pipe 11, in the side wall of medical material pipe 11 On be provided with hole 12 or through hole 13, radioactive source 14 is connect by medical adhesive 15 with hole 12 or through hole 13.
The outer diameter of medical material pipe 11 is 0.3mm~2mm, and length is 10mm~1000mm.
Medical material is gold, silver, platinum, tantalum, niobium, zirconium, medical stainless steel, medical titanium, medical titanium alloy, Co-Cr-Mo conjunction Gold, gathers Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, polyether-polyurethane, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon Methyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polystyrene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable seam Zygonema;The medical adhesive 15 is medical p-type glue, medical EC type glue, medical inosculating type glue, medical ZT type glue or bone cement.
The number of hole 12 or through hole 13 is 1-15.
The both ends of medical material pipe 11 and fixing clamp, snak link or button are flexibly connected.
The invention has the benefit that (1) is easy to operate, operating time is short;(2) realize that radioactive source is accurate in tumour Positioning, avoids the variation that source positions are influenced because of organ activity;(3) falling off or migrating for radioactive source is avoided, is reduced secondary Effect, good effect;(4) after treating, taking-up radioactive source can be facilitated, noresidue reduces the unnecessary irradiation of normal tissue, reduces Side reaction;It keeps organ complete and function perfects.
Detailed description of the invention
Fig. 1 is the first easily from the cross-section structure of the medical material silk of the Inner irradiation device taken out in vivo (setting is fluted) Schematic diagram.
Fig. 2 is that the first easily shows from the cross-section structure of the medical material silk (being provided with hole) of the Inner irradiation device taken out in vivo It is intended to.
Fig. 3 easily shows from the cross-section structure of the medical material pipe (being provided with hole) of the Inner irradiation device taken out in vivo for second It is intended to.
Fig. 4 is second easily from the section knot of the medical material pipe (being provided with through hole) of the Inner irradiation device taken out in vivo Structure schematic diagram.
Fig. 5 is snak link structural schematic diagram.
Fig. 6 is fixed folder structure schematic diagram.
Fig. 7 is one kind easily from the implanting state schematic diagram of the Inner irradiation device taken out in vivo.
Specific embodiment
Medical p-type glue, medical EC type glue, medical inosculating type glue, medical ZT type glue are purchased from the limited public affairs of Guangzhou white clouds medical adhesive Department, bone cement are purchased from Beijing's JaRa and praise science and technology limited Company.
The source of above-mentioned glue is intended merely to enable those skilled in the art to better implement the present invention, but can not be to this Invention is limited in any way.
The present invention will be further described below with reference to the drawings.
It is a kind of easily from the Inner irradiation device (see Fig. 1, Fig. 2) taken out in vivo, including medical material silk 1, in medical material silk 1 Upper setting fluted 2 or hole 3, radioactive source 4 are fixedly connected by medical adhesive 5 with groove 2 or hole 3.
1 diameter of medical material silk is preferably 1mm, can also select the arbitrary number in 0.3mm~2mm, such as 0.3mm, 0.5mm, 0.8mm, 1.2mm, 2mm etc..
Length is preferably 50mm, can also select the arbitrary number of 10mm~1000mm, such as 10mm, 60mm, 80mm, 100mm, 150mm, 300mm, 500mm, 1000mm etc..
Medical material is preferably niti-shaped memorial alloy, can also be selected: gold, silver, platinum, tantalum, niobium, zirconium, medical stainless steel, Medical titanium, Co-Cr-Mo alloy, Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, polyether-polyurethane, is gathered medical titanium alloy Tetrafluoroethene, polyester, nylon, polymethyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polystyrene, gathers silicon rubber Vinyl alcohol, poly(aryl ether ketone) or nonabsorable suture;
The medical adhesive 5 is medical p-type glue, medical EC type glue, medical inosculating type glue, medical ZT type glue or bone cement.
The number in groove 2 or hole 3 is any several in 1-15.
The both ends of medical material silk 1 and fixing clamp, snak link or button 6 are flexibly connected.
Second of Inner irradiation device (see Fig. 3, Fig. 4) easily taken out, including medical material pipe 11, in medical material pipe 11 Hole 12 or through hole 13 are provided on side wall, radioactive source 14 is connect by medical adhesive 15 with hole 12 or through hole 13.
The outer diameter of medical material pipe 11 is preferably 1mm, can also select the arbitrary number in 0.3mm~2mm, such as 0.3mm, 0.5mm, 0.8mm, 1.2mm, 2mm etc..
Length is preferably 50mm, can also select the arbitrary number of 10mm~1000mm, such as 10mm, 60mm, 80mm, 100mm, 150mm, 300mm, 500mm, 1000mm etc..
Medical material is preferably niti-shaped memorial alloy, can also select gold, silver, platinum, tantalum, niobium, zirconium, medical stainless steel, Medical titanium, Co-Cr-Mo alloy, Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, polyether-polyurethane, is gathered medical titanium alloy Tetrafluoroethene, polyester, nylon, polymethyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polystyrene, gathers silicon rubber Vinyl alcohol, poly(aryl ether ketone) or nonabsorable suture;
The medical adhesive (15) is medical p-type glue, medical EC type glue, medical inosculating type glue, medical ZT type glue or bone cement.
The number of hole 12 or through hole 13 is any several in 1-15.
The both ends of medical material fiber tube 11 and fixing clamp, snak link or button are flexibly connected.
Radioactive source 4 or 14 is iodine-125, palladium -103, Radium-224, cesium-131, Iridium-192 source, ytterbium -169, phosphorus -32 and Yttrium-90. Preferably iodine-125, palladium -103, Radium-224, cesium-131.
Radioactive source is spherical or cylinder, is dimensioned slightly smaller than groove 2 or hole 3, or be slightly less than hole 12 or through hole 13.
The shape of groove of the invention, hole or through hole is round, rectangle or stick.
Medical material silk or medical material pipe are also possible to ellipse perpendicular to the section configuration preferably circle of long axis, Rectangle or other geometry polygons, but consider the impression and applicability of patient, section is preferably circular.
The fixing clamp being flexibly connected with the end of medical material silk or pipe, snak link or button are commercially available.Including different several What shape, it is contemplated that present invention preferably uses snak links for applicability.
The operation that radioactive source is put into groove, hole or through hole is as follows:
Medical adhesive is applied at groove, hole or through hole;Wherein by radioactive source merging, 3min~10min is placed.
It is a kind of easily from the use of the Inner irradiation device (abbreviation radiotheraphy device) taken out in vivo (for treat hand, foot, ear, The shallower tumour such as tongue, nasal cavity, incidence, mammary gland): according to patient tumors size determine needed for place radiotheraphy device quantity and Fig. 7 is seen in position, and radiotheraphy device is placed in implant needle or implanting device, after passing through tumour and skin with implant needle or implanting device, uses Push rod releases radiotheraphy device, and the position of radioactive source is adjusted by the medical material silk or medical material pipe that pull radiotheraphy device, is taken out Implant needle or implanting device out are exposed in extracutaneous medical material silk 1 with fixing clamp (can also use snak link or button) fixation Or the both ends of medical material pipe 11, carry out radiotherapy.After treatment end, the fixing clamp (snak link or button) of one end is removed, from another One end pulls out radiotheraphy device.
The above content is illustrate the specific embodiment party, and it cannot be said that of the invention to what the present invention was done in conjunction with the embodiments Formula is only limitted to these explanations.For general technical staff of the technical field of the invention, present inventive concept is not being departed from Under the premise of, several simple deductions and transformation can also be made, all shall be regarded as belonging to protection scope of the present invention.

Claims (10)

1. one kind is easily from the Inner irradiation device taken out in vivo, it is characterized in that including medical material silk (1), in medical material silk (1) Upper setting fluted (2) or hole (3), radioactive source (4) are connect by medical adhesive (5) with groove (2) or hole (3).
2. the apparatus according to claim 1, it is characterized in that the diameter of the medical material silk (1) is 0.3mm~2mm, it is long Degree is 10mm~1000mm.
3. the apparatus according to claim 1, it is characterized in that the medical material be gold, silver, platinum, tantalum, niobium, zirconium, it is medical not Become rusty steel, medical titanium, medical titanium alloy, Co-Cr-Mo alloy, Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, the poly- ammonia of polyethers Ester, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon, polymethyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polyphenyl second Alkene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable suture;The medical adhesive 5 is medical p-type glue, medical EC type glue, medical kiss Mould assembly glue, medical ZT type glue or bone cement.
4. the apparatus according to claim 1, it is characterized in that the number of the groove (2) or hole (3) is 1-15.
5. device described in one of -4 according to claim 1, it is characterized in that both ends and fixation in the medical material silk (1) Folder, snak link or button movable (6) connection.
6. one kind is easily from the Inner irradiation device taken out in vivo, it is characterized in that including medical material pipe (11), in medical material pipe (11) hole (12) or through hole (13) are provided on side wall, radioactive source (14) passes through medical adhesive (15) and hole (12) or through hole (13) it connects.
7. device according to claim 6, it is characterized in that the outer diameter of the medical material pipe (11) is 0.3mm~2mm, it is long Degree is 10mm~1000mm.
8. device according to claim 6, it is characterized in that the medical material be gold, silver, platinum, tantalum, niobium, zirconium, it is medical not Become rusty steel, medical titanium, medical titanium alloy, Co-Cr-Mo alloy, Co-Ni-Cr-Mo alloy, niti-shaped memorial alloy, the poly- ammonia of polyethers Ester, polytetrafluoroethylene (PTFE), silicon rubber, polyester, nylon, polymethyl methacrylate, polyvinyl chloride, polyethylene, polypropylene, polyphenyl second Alkene, polyvinyl alcohol, poly(aryl ether ketone) or nonabsorable suture;The medical adhesive (15) is medical p-type glue, medical EC type glue, doctor With inosculating type glue, medical ZT type glue or bone cement.
9. device according to claim 6, it is characterized in that the number of the hole (12) or through hole (13) is 1-15.
10. the device according to one of claim 6-9, it is characterized in that both ends and fixation in the medical material pipe (11) Folder, snak link or button are flexibly connected.
CN201811113548.1A 2018-09-25 2018-09-25 It is a kind of easily from the Inner irradiation device taken out in vivo Pending CN109173091A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510924A (en) * 1980-07-10 1985-04-16 Yale-New Haven Hospital, Inc. Brachytherapy devices and methods employing americium-241
EP0500928B1 (en) * 1990-08-13 1999-03-03 GOOD, Roger R. Endocurietherapy
CN1761500A (en) * 2003-03-17 2006-04-19 医疗物理有限公司 Products and methods for brachytherapy
CN203736560U (en) * 2014-03-03 2014-07-30 李玉亮 Chemical radioactive particles and implantable equipment
CN105920727A (en) * 2016-04-11 2016-09-07 王娟 Radioactive particle chain and use method thereof
CN205672346U (en) * 2016-04-19 2016-11-09 牛洪欣 Recyclable conformal radiation particle cabin
US20170216499A1 (en) * 2000-11-16 2017-08-03 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510924A (en) * 1980-07-10 1985-04-16 Yale-New Haven Hospital, Inc. Brachytherapy devices and methods employing americium-241
EP0500928B1 (en) * 1990-08-13 1999-03-03 GOOD, Roger R. Endocurietherapy
US20170216499A1 (en) * 2000-11-16 2017-08-03 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
CN1761500A (en) * 2003-03-17 2006-04-19 医疗物理有限公司 Products and methods for brachytherapy
CN203736560U (en) * 2014-03-03 2014-07-30 李玉亮 Chemical radioactive particles and implantable equipment
CN105920727A (en) * 2016-04-11 2016-09-07 王娟 Radioactive particle chain and use method thereof
CN205672346U (en) * 2016-04-19 2016-11-09 牛洪欣 Recyclable conformal radiation particle cabin

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