CN203736560U - Chemical radioactive particles and implantable equipment - Google Patents
Chemical radioactive particles and implantable equipment Download PDFInfo
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- CN203736560U CN203736560U CN201420090861.9U CN201420090861U CN203736560U CN 203736560 U CN203736560 U CN 203736560U CN 201420090861 U CN201420090861 U CN 201420090861U CN 203736560 U CN203736560 U CN 203736560U
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Abstract
The utility model discloses chemical radioactive particles and implantable equipment. The chemical radioactive particles comprise particles which are provided with radioactive particles internally, wherein a plurality of particles are connected in sequence through support bodies so as to form a particle string; each support body and each particle are connected in a bonding manner. The chemical radioactive particles and the implantable equipment are beneficial to uniform implanting of the particles.
Description
Technical field
This utility model relates to a kind of for as the radioactive particle of the puncture for treating of tumor or Interventional radiology and implanting device.
Background technology
Radioactive substance has been widely used in medical field at present, as under CT or ultrasonic guidance the Radioisotopes seed such as I125, Pd 103 by means of puncture needle (full name insertion puncture needle, be called for short puncture needle) be implanted to the selected position of tumor, treat, be called as I125 particle implanted treatment in medical circle.
As direct implantation I125 particle, suppress tumor growth, reach the same or better effect of conventional therapy, and retained its physiological function.In addition, for radical surgery and cervical cancer, the Nasopharyngeal Carcinoma Patients that some cannot be performed the operation of being unwilling, it is also good selection that I125 particle is implanted.
Radioactive particle claims again radioactive sealed seed source, conventionally referred to as particle (below all referred to as particle), as shown in Figure 1, for a kind of basic block diagram of particle, conventionally it has a titanium shell 2(and is generally titanium alloy tube), entirety is column structure, two ends sealing-in, the general sealing-in bulb 1 that forms, the cavity volume forming is built-in with the particle body 3 of the radiosiotope formation of doses.Wherein the compatibility of titanium alloy and tissue is good, avoids the rejection of sensitive organization.
In order to reduce normal tissue radioactive dose, need to control the operating distance of radioactive particle, if its radiation diameter of general control is 17mm, its entire length is generally 4.5mm, and titanium alloy tube diameter is generally at 0.8mm.According to said structure, at the implantation position as in tumor, can make its operating distance substantially fall in range of tumor by particle, and can not produce too much influence by normal tissue.
But the common volume ratio of tumor is larger, individual particle is not enough to meet the needs for the treatment of conventionally.Referring to Figure of description 2, is the working state schematic representation of traditional particle implanting device, and particle 4 should be uniformly distributed in tumor 5, makes the tumor can be by omnibearing irradiation.About implanting device, conventionally comprise a puncture needle 6 and by puncture needle 6 endoporus, particle 4 is pushed into the push rod 7 of the current position of puncture needle head end, and the support of auxiliary fixing puncture needle 6.
But simple by means of puncture needle 6 and push rod 7, and support can not be implanted particle 4 uniformly, be as tumor 5, the form of himself is at any time all in variation, and himself not rigid body, affected by this, corresponding to each selected implantation position, get involved in the process withdrawing gradually after certain depth because the tractive that tumor body moves and the viscous that rubs produces is out of shape according to external range marker (conventionally on push rod) puncture needle, cause puncture needle not stop exactly, even far apart with desirable position, thereby cannot implant particle uniformly, cannot meet desirable treatment requirement.
Utility model content
In view of this, this utility model, from the viewpoint of particle, proposes a kind of chemoluminescence particle on the one hand, is beneficial to the even implantation of particle; A kind of implanting device of implanting for this chemoluminescence particle is proposed on the other hand.
This utility model is by the following technical solutions:
A kind of chemoluminescence particle, comprises the particle that is built-in with radioactive substance, and multiple particles connect in turn by supporter, thus constituent particle string;
Supporter and interparticle syndeton are bonding.
Above-mentioned chemoluminescence particle, is heat setting glue for the material boning, thereby forms gel layer between supporter and particle.
Above-mentioned chemoluminescence particle, described supporter is powder column.
Above-mentioned chemoluminescence particle, described powder column comprises packaging body and the medicine that is held into this packaging body, wherein packaging body is titanium guard.
Above-mentioned chemoluminescence particle, particle end is bulb, correspondingly, powder column termination is Internal Spherical Surface.
Above-mentioned chemoluminescence particle, described particle leaves bookbinding section in end, and correspondingly, the bookbinding section connector that bookbinding forms is between two configured to described supporter.
A kind of chemoluminescence particle implanting device, comprises the fixture of puncture needle and fixing puncture needle needle stand, and with the push rod guide hole that puncture needle needle stand coaxial line is set, also comprise:
Connection tube, is connected between fixture and push rod guide hole, and is provided with two in a side and is pressed into side opening;
Particle cabin, corresponding go out particle mouth and is connected in one and is pressed into side opening, and is provided with and controls the flashboard that particle deliver from vault opens and closes going out particle mouth;
Powder column cabin, corresponding go out powder column mouth and is connected in another and is pressed into side opening, and is provided with and controls the flashboard that powder column deliver from vault opens and closes going out powder column mouth;
Glue cabin, is connected on powder column cabin going out each ground, powder column two ends corresponding to powder column mouth place, and the corresponding glue hole for plastic emitting aligns powder column termination; And
Solidification equipment, is arranged on fixture place, so that powder column and interparticle glue-line after connecting are cured.
Above-mentioned chemoluminescence particle implanting device, is slide for the seat of supporting adn fixing device, connection tube, particle cabin, powder column cabin, solidification equipment, and this slide has the degree of freedom axially sliding along push rod guide hole.
Above-mentioned chemoluminescence particle implanting device, described fixture comprises two parts of upper and lower deciliter, is wherein positioned at partial fixing setting below, is positioned in the part of the part above chain connection by side below being positioned at;
A side with respect to hinge is provided with lock section, and this lock section is Spring lock catch.
Above-mentioned chemoluminescence particle implanting device, the cavity volume in described powder column cabin is rectangular body cavity, inside establishes spring, so that powder column deliver from vault pressure to be provided.
Can find out from above structure, according to this utility model, by supporter, as powder column, evenly spacer particle, forms the particle string each other with secure support, after pushing, can ensure that the distance between particle is even, and compliant requirement.Because the process of extracting puncture needle out is the contraction process of tumor, if the suffered pressure of advocating of particle string, therefore, mutual supporting role can make it possess stable state.
Brief description of the drawings
Fig. 1 is a kind of morphology of particles figure, mid-sectional in figure.
Fig. 2 uses puncture needle that particle is implanted to the state diagram in tumor.
Fig. 3 is according to chemoluminescence particle structure schematic diagram of the present utility model.
Fig. 4 is a kind of chemoluminescence particle implanting device structure diagram, omits push rod and frame corresponding to slide.
Fig. 5 is the structure principle chart in a kind of powder column cabin.
Fig. 6 is a kind of reed structure schematic diagram.
In figure: 1. sealing-in bulb, 2. titanium shell, 3. particle body, 4. particle, 5. tumor, 6. puncture needle, 7. push rod, 8. gel layer, 9. powder column.
10. needle holder folder, 11. reeds, 12. flashboards, 13. particle cabins, 14. powder column cabins, 15. flashboards, 16. connection tubes, 17. push rod guide holes, 18. slides, 19. grooves, 20. springs, 21. cavity volumes, 22. glue chambers, 23. pressure chamberes, 24. glue cabins, 25. glue holes.
Detailed description of the invention
A kind of chemoluminescence particle, its general performance is a particle string, distance between the particle 4 that distance between particle 4 in particle string is code requirement, because this distance is by the appearance explanation of particle 4 is limited, in other words,, by those skilled in the art is known, do not repeat them here.
Particle 4, as described in the background section, generally adopts I125 or Pd 103 particle, is namely built-in with the particle 4 of I125 or Pd 103, forms particle string, just needs multiple particles 4, and they connect in turn by supporter, thus constituent particle string.
Supporter and interparticle syndeton, for bonding, are beneficial to how many field fabrications for the string of each particle.
No matter be the material for boning, or supporter all needs to consider rejection, therefore, because adopting medical material, supporter is as the supporting construction that adopts titanium alloy to make, and bonding material uses medical bio glue.
As shown in Figure 3, about the material for boning, be preferably heat setting glue, by of short duration heating, can fast setting, be convenient to field fabrication, thereby be combined firmly gel layer 8 in supporter formation with between particle 4.
The glue that bonding can also adopt photocuring, directly irradiates, and it is solidified, but need to configure transparent unit, so that the light source that photocuring needs is introduced.Light uses more intense ultraviolet radiation admittedly conventionally, and on-the-spot needed equipment individual relative is larger, and operation is not very sensitive, but is also a kind of selection preferably.
No matter be that light is consolidated or heat setting, have specific glue object, about correspondence, those skilled in the art can select accordingly.
Further, about supporter, in certain embodiments, described supporter is powder column 9.Can mate like this treatment, make the powder column 9 of required medicine, not only can make the even interval of particle 4, and can utilize the slow releasing function of powder column to carry out Drug therapy, thereby the Drug therapy of making and chemotherapy organically combine.
About medicine, some drugs itself can be made into the column construction with certain rigidity, but a lot of medicines are difficult to make this structure, use for this class medicine just needs additional support, for this reason at some in the embodiment for such medicine, described powder column 4 comprises packaging body and the medicine that is held into this packaging body, and wherein packaging body is titanium guard.
Titanium or titanium alloy have reasonable biocompatibility, and net cover structure is conducive to the slow release of medicine.
Also can use titanium or titanium alloy guard for the medicine that can be made into powder column.
In order to improve the reliability of combination, particle 4 ends are bulb, and as Fig. 3 left end, correspondingly, powder column 9 terminations are Internal Spherical Surface, adopt the structure that powder column 9 and gel layer 8 are cut open to demonstrate spherical structure in figure.According to this structure, composition surface area is large, on the other hand, can produce spacing left and right radially, ensures integrally-built stability, and disconnection probability reduces.
In certain embodiments, described particle 4 leaves bookbinding section in end, and correspondingly, the bookbinding section connector that bookbinding forms is between two configured to described supporter.Bookbinding also can complete at scene, and bookbinding can adopt mechanically binding, therefore needs the part that is connected, and as biomass rivet, directly adopts riveting gun to connect one by one.
Chemoluminescence particle can clearerly reflect its use advantage by implanting device once.
A kind of chemoluminescence particle implanting device, as shown in Figure 4, comprises the fixture of puncture needle 6 and fixing puncture needle needle stand, and the push rod guide hole 17 of setting with puncture needle needle stand coaxial line.
Because the needle body of puncture needle 6 has the face of cylinder; needle stand has a tapering end conventionally; a cylinder section; conventionally be also provided with fin, therefore, by profile simply connect can carry out axial fixing; again because needle stand has certain axial length conventionally; therefore,, by the cooperation of profile, also can carry out radially fixing.
Puncture needle 6 fixedly see known particle implanting device, comparatively general, the use of particle string is not exerted an influence, therefore, the fixing apparatus for puncture needle that known particle implanting device uses also can use.
Than known particle implanting device, as shown in Figure 4, figure further comprises:
Connection tube 16, be connected between fixture and push rod guide hole 17, and be provided with two in a side and be pressed into side opening, this part is connected in turn for particle 4 and powder column 9, one of them side opening is pressed into for particle 4, and another side opening is pressed into for powder column 9, like this, push rod 7 no action once just can connect a particle 4 and a powder column 9, with bullets loading comparing class seemingly.
And then once configure:
Particle cabin 13, corresponding go out particle mouth and be connected in one and be pressed into side opening, and be provided with and control the flashboard 12 that particle deliver from vault opens and closes going out particle mouth, when use, one granule 4 enters connection tube, the particle that can support above no longer falls, push rod pushes away away this particle can stepping back, more than the space that goes out have the particle closing on to fill up.
Based on same consideration, configuration powder column cabin 14, corresponding go out powder column mouth and is connected in another and is pressed into side opening, and is provided with and controls the flashboard 15 that powder column deliver from vault opens and closes going out powder column mouth.
About flashboard 12 and flashboard 15, in the time of the further intervention not needing as powder column 9, after push rod 7 inserts, close upper flashboard 15.
For as the whereabouts of up-down structure, as flashboard 15 arranges very simply, only need the degree of freedom of pull to control.Because particle 4 and powder column 9 have cylindrical structure, in other words, there is certain guide effect again, convenient carry out with flashboard adjacent as the blocking of particle 4.
Below about the setting in glue cabin 24, as shown in Figure 5, glue cabin 24 is connected on powder column cabin going out each ground, powder column two ends corresponding to powder column mouth place, the corresponding glue hole 25 for plastic emitting aligns powder column 9 terminations, like this in the time that a powder column 9 drops to 25 position, glue hole, glue will enter, blind, because the mobility of glue is poor, smaller gap can not produce the leakage of glue, therefore, as long as the gap between powder column and cavity volume 21 arranges rationally, can not produce scurrying out of glue, person skilled in art can arrange this distance according to the mobility of glue can be according to the mobility of glue with the technical staff in field.
Solidification equipment, selects according to the character of glue, as light binding, adopts light to set firmly standby, if heat setting glue directly adopts firing equipment, is arranged on fixture place, so that powder column and interparticle glue-line after connecting are cured.
Preferably heat setting glue, coupling is heating and curing.
Not shown rack section in Fig. 4, do not express push rod 7 yet, but push rod guide hole 17 defines the occupation mode of push rod 7, push rod 7 slide 18 to that indicated in the drawings has relative motion relation simultaneously, therefore, can adopt as required push rod 7 moving, or the moving type of drive of slide 18, the structure that nature can also adopt push rod 7 and slide 18 to be furnished with separately driving device.
As last a kind of selection, in advance, slide 18 presss from both sides 10 by needle holder and carries puncture needle 6 and be fixedly installed, and opens 15, one particles 4 of flashboard 12 and flashboard and a powder column 9 and falls into connection tube 16, push rod 7 promotes once particle 4 is connected and is pushed with powder column 9, then withdraw, falling into a particle 4 and a powder column 9, repeatable operation, obtain a predetermined quantity particle 4, form particle string.Then push rod 7 is fixing, and slide 18 moves, and slide 18 withdraws in other words, and puncture needle 6 is pulled out, and particle string is stayed as tumor 5 corresponding positions because of relatively fixing of push rod 7.
Seat for supporting adn fixing device, connection tube, particle cabin, powder column cabin, solidification equipment is slide 18, and this slide 18 has the degree of freedom axially sliding along push rod guide hole 17.For providing the trajectory diagram that slide 18 moves not represent, but rectilinear motion is one of basic exercise in machinery, does not repeat them here about straight-line mechanism, and in Fig. 4, centrage below represents the direction that slide 18 moves.
Fixing about push rod 7, can be directly manually fixing, in other words, directly withstands push rod 7 with hands, slide rollback, and stick shift is lived push rod 7 and is not allowed its rollback.
Also can special fixed structure be set to push rod, can directly adopt removable baffle plate, simple in structure, and set easily and fast, for example, can directly insert as arranged in the slot in frame.
About described fixture, in certain embodiments, comprise two parts of upper and lower deciliter, be wherein positioned at partial fixing setting below, be positioned in the part of the part above chain connection by side below being positioned at;
A side with respect to hinge is provided with lock section, and this lock section is Spring lock catch, is convenient to quick connection.
The folding of top and the bottom, based on hinge, also facilitates folding.
As previously mentioned, have the axially symmetric structure of coupling puncture needle 6 between top and the bottom, be specially a die cavity, have axially symmetric structure, front and back connect.
By the structure of upper and lower folding, then realize and being fixed by the direct cooperation of profile, simple in structure.
In the structure shown in Fig. 4 left end, the structure that the needle holder folder 10 of up-down structure adopts reed 11 to coordinate with groove 19, wherein the structure of reed 11 can be with reference to shown in figure 6, realize spacingly by the structure on vertical plane, its upper end is stiff end, by elastic deformation, depart from spacing, down button, stress deformation, reed 11 bottoms are included in corresponding groove 19.
Be rectangular body cavity about the cavity volume in described powder column cabin 14, inside establish spring 20, so that powder column deliver from vault pressure to be provided, be similar to cartridge clip, only in this case, adopt the keying of flashboard control powder column deliver from vault.
About glue cabin 24, also can adopt spring structure to provide glue laminated power, wherein as shown in Figure 5, glue chamber 22 is for holding glue, pressure chamber 23 is for pressure is provided, and its entirety forms cylindricality cavity, cuts apart plastic chamber 22 and pressure chamber 23 by piston, piston is arranged on the Spring driving of pressure chamber 23, provides glue laminated power.
Claims (10)
1. a chemoluminescence particle, comprises the particle (4) that is built-in with radioactive substance, it is characterized in that, multiple particles (4) connect in turn by supporter, thus constituent particle string;
Supporter and interparticle syndeton are bonding.
2. chemoluminescence particle according to claim 1, is characterized in that, is heat setting glue for the material boning, thereby forms gel layer (8) between supporter and particle (4).
3. chemoluminescence particle according to claim 1 and 2, is characterized in that, described supporter is powder column (9).
4. chemoluminescence particle according to claim 3, is characterized in that, described powder column comprises packaging body and the medicine that is held into this packaging body, and wherein packaging body is titanium guard.
5. chemoluminescence particle according to claim 3, is characterized in that, particle (4) end is bulb, and correspondingly, powder column (9) termination is Internal Spherical Surface.
6. chemoluminescence particle according to claim 1, is characterized in that, described particle (4) leaves bookbinding section in end, and correspondingly, the bookbinding section connector that bookbinding forms is between two configured to described supporter.
7. a chemoluminescence particle implanting device, comprises the fixture of puncture needle (6) and fixing puncture needle needle stand, and with the push rod guide hole (17) that puncture needle needle stand coaxial line is set, it is characterized in that, also comprise:
Connection tube (16), is connected between fixture and push rod guide hole (17), and is provided with two in a side and is pressed into side opening;
Particle cabin (13), corresponding go out particle mouth and is connected in one and is pressed into side opening, and is provided with and controls the flashboard (12) that particle deliver from vault opens and closes going out particle mouth;
Powder column cabin (14), corresponding go out powder column mouth and is connected in another and is pressed into side opening, and is provided with and controls the flashboard (15) that powder column deliver from vault opens and closes going out powder column mouth;
Glue cabin (24), is connected on powder column cabin going out each ground, powder column two ends corresponding to powder column mouth place, and the corresponding glue hole (25) for plastic emitting aligns powder column termination; And
Solidification equipment, is arranged on fixture place, so that powder column and interparticle glue-line after connecting are cured.
8. chemoluminescence particle implanting device according to claim 7, it is characterized in that, seat for supporting adn fixing device, connection tube, particle cabin, powder column cabin, solidification equipment is slide (18), and this slide (18) has the degree of freedom axially sliding along push rod guide hole (17).
9. chemoluminescence particle implanting device according to claim 7, it is characterized in that, described fixture comprises two parts of upper and lower deciliter, is wherein positioned at partial fixing setting below, is positioned in the part of the part above chain connection by side below being positioned at;
A side with respect to hinge is provided with lock section, and this lock section is Spring lock catch.
10. chemoluminescence particle implanting device according to claim 7, is characterized in that, the cavity volume in described powder column cabin (14) is rectangular body cavity, inside establishes spring (20), so that powder column deliver from vault pressure to be provided.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420090861.9U CN203736560U (en) | 2014-03-03 | 2014-03-03 | Chemical radioactive particles and implantable equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420090861.9U CN203736560U (en) | 2014-03-03 | 2014-03-03 | Chemical radioactive particles and implantable equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203736560U true CN203736560U (en) | 2014-07-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420090861.9U Expired - Fee Related CN203736560U (en) | 2014-03-03 | 2014-03-03 | Chemical radioactive particles and implantable equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203736560U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109173091A (en) * | 2018-09-25 | 2019-01-11 | 天津赛德医药研究院有限公司 | It is a kind of easily from the Inner irradiation device taken out in vivo |
| WO2021115125A1 (en) * | 2019-12-11 | 2021-06-17 | 先健科技(深圳)有限公司 | Left atrial appendage occluder |
-
2014
- 2014-03-03 CN CN201420090861.9U patent/CN203736560U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109173091A (en) * | 2018-09-25 | 2019-01-11 | 天津赛德医药研究院有限公司 | It is a kind of easily from the Inner irradiation device taken out in vivo |
| WO2021115125A1 (en) * | 2019-12-11 | 2021-06-17 | 先健科技(深圳)有限公司 | Left atrial appendage occluder |
| US11918228B2 (en) | 2019-12-11 | 2024-03-05 | Lifetech Scientific (Shenzhen) Co., Ltd. | Left atrial appendage occluder |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140730 Termination date: 20150303 |
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| EXPY | Termination of patent right or utility model |