CN102151346A - Hypodermic implantation type medicine feeder - Google Patents

Hypodermic implantation type medicine feeder Download PDF

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Publication number
CN102151346A
CN102151346A CN2011101051079A CN201110105107A CN102151346A CN 102151346 A CN102151346 A CN 102151346A CN 2011101051079 A CN2011101051079 A CN 2011101051079A CN 201110105107 A CN201110105107 A CN 201110105107A CN 102151346 A CN102151346 A CN 102151346A
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CN
China
Prior art keywords
injection
injection tube
medicine
liquid storage
medicine bag
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011101051079A
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Chinese (zh)
Inventor
大平永敏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANGHAI BAITA MEDICAL PHARMACEUTICAL CO Ltd
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SHANGHAI BAITA MEDICAL PHARMACEUTICAL CO Ltd
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Priority to CN2011101051079A priority Critical patent/CN102151346A/en
Publication of CN102151346A publication Critical patent/CN102151346A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a hypodermic implantation type medicine feeder, and relates to a hypodermic injector in a medical apparatus, aiming at solving the defects that a medicine bag of the existing hypodermic implantation type medicine feeder has to be injected with the medicine liquid by the medical department at a time or the existing hypodermic implantation type medicine feeder has to be withdrawn from the human body to inject the medicine after the medical liquid is used up. The hypodermic implantation type medicine feeder comprises a shell and an injection pump component arranged in the shell, wherein the injection pump component comprises an injection push rod, a liquid storage medicine bag and an injection barrel, the injection push rod is inserted into the injection barrel and can slide along with the inner wall of the injection barrel, and the liquid storage medicine bag is communicated with the injection barrel. The injection pump component further comprises at least one of medicine injection cavities communicated with the liquid storage medicine bag, each medicine injection cavity is provided with a medicine liquid injection port, and each medicine liquid injection port is arranged outside the shell. The hypodermic implantation type medicine feeder can be injected with the medicine which can be used for a long time, and the medicine feeding is manually controlled by the patient according to the use level at a time. The hypodermic implantation type medicine feeder is suitable for the cancer-curing chemotherapy feeding and the other disease which needs the internal guide feeding.

Description

A kind of Endermic implantating doser
Technical field
The present invention relates to the hypodermic injection unit in a kind of medical apparatus and instruments, relate in particular to a kind of Endermic implantating doser.
Background technology
The Endermic implantating doser is the new type medical equipment of a kind of formation " drug channel in the human body ", it is used for burying in the body guidance quality zone administration, can provide the repetition passage to selected target tissue or organ, be used for the cancerous area chemotherapy, the medicine of analgesia therapy purpose comes into operation and the treatment of other diseases, make medicine can be directly, be transported to target tissue or organ by this device repeatedly.It can improve tens of times to over one hundred times of the liquor strengths of local organization or organ than conventional vein or intramuscular injection method, and long term compares with vein or intramuscular injection medication administration method in target tissue, can alleviate because the general medication, the untoward reaction that causes can significantly improve therapeutic effect.
Chang Yong doser clinically as the venous transfusion device, mostly is the external doser that is provided with, the mode of veins indwelling catheter, treatment local patholoic change or systemic disease; The perhaps external syringe that is provided with at the epidural space inlying catheter, injects analgesic treatment cancer of late stage pain etc.The shortcoming of treated in vitro device is a complicated operation, and patient's activity is subjected to very big restriction, and conduit comes off easily and the danger of local infection is arranged.
The present situation of the doser of implantation property both at home and abroad product: be divided into disposable perfusion doser and electrodynamic type automatic chemical feeding device two big classes.The former each administration must be injected medicinal liquid to medicine bag to medical institutions; The medicinal liquid that the latter then injects uses up or the electric energy of battery when exhausting, and must carry out dabbling drug again from withdrawing device in the body, uses very inconvenience, and costs an arm and a leg.
Summary of the invention
At the shortcoming of above-mentioned domestic and international existing implantable drug delivery system, but the purpose of this invention is to provide life-time service behind a kind of dabbling drug, manually control by the patient, can be regularly and the Endermic implantating doser of dosed administration.
The technical solution adopted for the present invention to solve the technical problems is: it comprises housing and is arranged at the intravital syringe pump assembly of described shell, described syringe pump assembly comprises injection catch bar, liquid storage medicine bag and injection tube, described injection catch bar is inserted in the described injection tube and can slides along the injection tube inwall, described liquid storage medicine bag is connected with described injection tube, and described housing is provided with a medicinal liquid inlet that is used for to described liquid storage medicine bag injection medicinal liquid.。
Further, between described medicinal liquid inlet and described liquid storage medicine bag, also be provided with at least one medicine that is connected with described liquid storage medicine bag and described medicinal liquid inlet respectively and inject chamber.
Further, one end of described injection catch bar is connected with injection ram, described injection ram is inserted in the described injection tube and can slides along the injection tube inwall, and the other end of described injection catch bar is positioned at outside the described housing, and the boss on the described injection catch bar contacts with described inner walls.
Further, described syringe pump assembly also comprises the injection tube fixed mount that is used for fixing injection tube, and described injection tube fixed mount is arranged at described enclosure interior central authorities.
Further, described syringe pump assembly also comprises the spring that is sleeved on the described injection catch bar, and described spring is between described boss and described injection tube fixed mount.
Further, described syringe pump assembly also comprises button, and described button is arranged at and is positioned on the outer described injection catch bar of described housing.
Further, the ultimate range of described button pressed downwards equates with the height of described injection tube inner chamber.
Further, described liquid storage medicine bag is made by medical organic silicon rubber material, and described liquid storage medicine bag is enclosed in the described injection catch bar outside, and the cross section of described liquid storage medicine bag in the form of a ring.
Further, second transfusion catheter that described injection tube is connected with described liquid storage medicine bag is provided with the injection tube inlet non-return valve that prevents that medicinal liquid from refluxing, and the connector that described injection tube is connected with described extraneous conduit is provided with the injection tube outlet non-return valve that prevents that medicinal liquid from refluxing.
The effect of this patent is: after doser of the present invention is implanted subcutaneous tissue, the liquid storage medicine bag is disposable can to pour into the long-term prescription amount, and according to the needs of dosage every day, patient's pressing button is by injection tube liquid medicine injection in target tissue, once push and inject quantitative medicinal liquid, carry out oneself's control medication.When the dose of liquid storage medicine bag is not enough, inject medicinal liquid repeatedly by the medicinal liquid inlet, the inconvenience of the perfusion administration of avoiding frequently going to the hospital.This device can permanent subcutaneous implantation, and the adventitia aseptic of medical organic silicon rubber material is strong, should not leak outside, safe.This apparatus structure is simple, cheap, is easy to carry.The present invention not only can improve the clinical treatment level, the Endermic implantating doser that provides easy to use and had wide range of applications for extensive patients also, particularly, bring into play very big effect to cancer patient's the cancer drug therapy and the pain therapy of patient with advanced cancer.
Description of drawings
The invention will be further described below in conjunction with drawings and Examples;
Fig. 1 is an external structure sketch map of the present invention;
Fig. 2 is an internal structure sketch map of the present invention;
Fig. 3 is the structural representation of injection catch bar;
Fig. 4 is the structural representation of injection catch bar and injection tube position relation;
Fig. 5 is the structural representation of injection tube;
Fig. 6 is the structural representation of injection tube and position of valve relation;
Fig. 7 is the structural representation of liquid storage medicine bag;
The number in the figure explanation:
1-housing 2-adventitia 3-syringe pump assembly 4-liquid storage medicine bag
The 5-medicine injects chamber 6-medicinal liquid inlet 7-first transfusion catheter 8-injection catch bar
9-boss 10-spring 11-button 12-injection ram 13-injection tube
The 14-second transfusion catheter 15-medicine liquid outlet 16-injection tube fixed mount
The extraneous conduit 20-of 17-suture hole 18-retainer ring 19-union joint
21-injection tube outlet non-return valve 22-injection tube inlet non-return valve
The specific embodiment
Embodiment one: in conjunction with Fig. 1 to Fig. 7 Endermic implantating doser of the present invention is described, this doser is made up of housing 1 and the syringe pump assembly 3 that is arranged in the housing 1.Housing 1 is the discus type, and its central authorities are thick, and to periphery attenuation gradually, and the bottom surface is smooth.The both sides of housing 1 outer wall respectively have a suture hole 17 to be used for doser is fixed in subcutis.Housing 1 can be made by polymethyl methacrylate (PMMA resin) macromolecular material.The adventitia of being made by medical organic silica gel 2 sealingly is coated on housing 1 outer surface, and because of silica gel material does not repel with body, it can reduce the injury to subcutis.
Syringe pump assembly 3 comprises injection catch bar 8, with the injection ram 12 that is connected of an end of injection catch bar 8, be sleeved on spring 9, injection tube 13 on the injection catch bar 8, be used for injection tube 13 is fixed in injection tube fixed mount 16, liquid storage medicine bag 4 and two medicines injection chambeies 5 that are connected with liquid storage medicine bag 4 on housing 1 inwall.Wherein, liquid storage medicine bag 4 is connected with injection tube 13 by second transfusion catheter 14, and injection ram 12 is inserted in the injection tube 13 and can slides along its inwall, forms the syringe state.The other end of injection catch bar 8 is positioned at outside the housing 1, and button 11 is installed, and the bottom of button 11 is provided with boss 9, and boss 9 is positioned at housing 1 and contacts with its inwall, being provided with of boss 9 limited the displacement of injecting catch bar 8, in order to avoid injection catch bar 8 ejects housings 1.Injection tube 13 inner space height and button 11 times are identical by ultimate range.Spring 10 is between boss 9 and injection tube fixed mount 16 upper surfaces.
Medicine injection 5 tops, chamber of being made by medical organic silica gel are provided with the medicinal liquid inlet 6 that is convex shape, and medicinal liquid inlet 6 is positioned at outside the housing 1.The silica gel thickness of medicinal liquid inlet 6 is bigger, and entry needle inserts injectable drug in medicine injects chamber 5 thus.It is rounded or oval that medicine injects chamber 5 cross sections, and its bottom is hard, can prevent that entry needle from penetrating and then puncturing liquid storage medicine bag 4.Medicine injects chamber 5 and is connected by first transfusion catheter 7 with liquid storage medicine bag 4.Two medicinal liquid inlets 6 are placed on housing 1 outer part and are coated by adventitia 2.The liquid storage medicine bag of being made by medical organic silicon rubber 4 surrounds ringwise in injection catch bar 8 outsides, and its cross section is rounded or square.Liquid storage medicine bag 4 communicates with injection tube 13 by second transfusion catheter 14 that is positioned at its sidewall below.The side of injection tube 13 bottoms is provided with medicine liquid outlet 15, and injection tube 13 is communicated with extraneous conduit 19 by the union joint 20 that is connected on the medicine liquid outlet 15.The below of injection tube fixed mount 16 is provided with passage, and second transfusion catheter 14 passes thus.Be equipped with injection tube inlet non-return valve 22(one-way cock in second transfusion catheter 14), can prevent that medicinal liquid from refluxing.Medicine liquid outlet 15 places of injection tube 13 are provided with injection tube outlet non-return valve 21, prevent that the medicinal liquid that flows to target tissue from refluxing.Extraneous conduit 19 can implanting tissue, in organ or the nervous system.
The occupation mode of this device is as follows:
One, operative procedure is installed: under aseptic operation, carry out the installation of doser, can be installed in the top of subcutaneous rib through the disinfectant doser.Cut disinfectant skin, separate subcutaneous tissue, form the space of device size, insert doser, utilize stitching thread doser and subcutaneous tissue to be fixed, prevent that doser from moving by suture hole 17.Then, with stitching thread that extraneous conduit 19 is fixing with retainer ring 18, in case extraneous conduit 19 causes medicine liquid leakage because of external force breaks away from union joint 20.The other end of extraneous conduit 19 is implanted the target tissue for the treatment of, and the skin suture operation finishes.
Two, Zhuan Zhi perfusion program: according to doctor's advice and disease course of treatment, configuration and the medicinal liquid of liquid storage medicine bag 4 with capacity, insert the medicinal liquid inlet 6 of projection with the syringe that has syringe needle, in injecting chamber 5, injects medicine quantitative medicinal liquid, medicinal liquid injects chamber 5 by medicine and flows into to liquid storage medicine bag 4 by first transfusion catheter 7, liquid storage medicine bag 4 inner liquid medicines flow in the chamber of injection tube 13 by second transfusion catheter 14, device is furnished with two medicines and injects chamber 5, if a medicine injects chamber 5 and breaks down, can use another one.
Three, treatment sequence: press...with one's finger and press button 11 till can't push, this moment, injection ram 12 closely arrived injection tube 13 bottoms, injection catch bar 8 is by promoting the medicinal liquid that piston 12 promotes in the injection tube 13, inject coupled logical extraneous conduit 19 by medicine liquid outlet 15, and then flow in the target tissue of implanting this conduit.Injection tube inlet non-return valve 22 on second transfusion catheter 14 is closed, and can prevent that the medicinal liquid in the injection tube 13 from refluxing in liquid storage medicine bag 4.
When finger release button 11 pressure relieves, spring 10 bounce-backs on the injection catch bar 8, injection ram 12 is set back, the negative pressure that injection ram 12 pumpbacks produce, can open the injection tube inlet non-return valve 22 of second transfusion catheter, 14 seams that communicate with liquid storage medicine bag 4, make the medicinal liquid in the liquid storage medicine bag 4 flow to injection tube 13, and then be injection tube 13 perfusion solution again.Meanwhile, injection tube 13 is closed with the injection tube outlet non-return valve 21 at extraneous conduit 19 connector places, prevents that the medicinal liquid that flows to target tissue from refluxing.
Liquid storage medicine bag 4 intracavity volumes can reach 10 milliliters, and according to injecting dosage the course of treatment, and injection tube 13 intracavity volumes can be set at the specification of 1 milliliter or 2 milliliters.Injection tube 13 inner liquid medicines can be set at a drug dosage, so the needs of patient's medication every day decision compression number.Also can adjust compression number according to regulating the liquor strength that injects.For example: a week is a course of treatment, medication every day once, the amount of at every turn making up a prescription is set at 7 milliliters by the adjusting of concentration.According to above setting, 7 milliliters medicinal liquid can inject in hospital in liquid storage medicine bag 4.After the patient goes home, push every day once, 1 milliliter of each administration after the week, is carried out perfusion to hospital again.Silica gel liquid storage medicine bag 4 is software capsules, its volume is along with the minimizing atrophy gradually of capsule inner liquid medicine, utilize the negative pressure of the pumpback generation of injection ram 12 in the injection tube 13, need not passage also can be to the intracavity perfusion of injection tube 13, after the medicinal liquid of liquid storage medicine bag 4 uses up, can refill medicinal liquid, liquid storage medicine bag 4 is restored to the original state.
The present invention has overcome subcutaneous drug delivery implant device under sealing state, if use rigid medicine bag, even increase negative pressure, also can't discharge the problem of medicinal liquid.The projection of button 11 is not higher than 2 millimeters of housing 1 outer surfaces, so, when unexpected [, also can not cause the injection of doser.
Those skilled in the art will recognize that; the above-mentioned specific embodiment is exemplary; be in order to make those skilled in the art can better understand this patent content; should not be construed as is restriction to this patent protection domain; change or modify so long as disclose spiritual any being equal to of being done, all fall into this patent protection domain according to this patent.

Claims (9)

1. Endermic implantating doser, it is characterized in that: it comprises housing and is arranged at the intravital syringe pump assembly of described shell, described syringe pump assembly comprises injection catch bar, liquid storage medicine bag and injection tube, described injection catch bar is inserted in the described injection tube and can slides along the injection tube inwall, described liquid storage medicine bag is connected with described injection tube, and described housing is provided with a medicinal liquid inlet that is used for to described liquid storage medicine bag injection medicinal liquid.
2. Endermic implantating doser according to claim 1 is characterized in that: also be provided with at least one medicine that is connected with described liquid storage medicine bag and described medicinal liquid inlet respectively and inject chamber between described medicinal liquid inlet and described liquid storage medicine bag.
3. Endermic implantating doser according to claim 1, it is characterized in that: an end of described injection catch bar is connected with injection ram, described injection ram is inserted in the described injection tube and can slides along the injection tube inwall, the other end of described injection catch bar is positioned at outside the described housing, and the boss on the described injection catch bar contacts with described inner walls.
4. Endermic implantating doser according to claim 1 is characterized in that: described syringe pump assembly also comprises the injection tube fixed mount that is used for fixing injection tube, and described injection tube fixed mount is arranged at described enclosure interior central authorities.
5. Endermic implantating doser according to claim 4 is characterized in that: described syringe pump assembly also comprises the spring that is sleeved on the described injection catch bar, and described spring is between described boss and described injection tube fixed mount.
6. Endermic implantating doser according to claim 3 is characterized in that: described syringe pump assembly also comprises button, and described button is arranged at and is positioned on the outer described injection catch bar of described housing.
7. Endermic implantating doser according to claim 6 is characterized in that: the ultimate range of described button pressed downwards equates with the height of described injection tube inner chamber.
8. Endermic implantating doser according to claim 1 is characterized in that: described liquid storage medicine bag is made by medical organic silicon rubber material, and described liquid storage medicine bag is enclosed in the described injection catch bar outside, and the cross section of described liquid storage medicine bag in the form of a ring.
9. Endermic implantating doser according to claim 1, it is characterized in that: second transfusion catheter that described injection tube is connected with described liquid storage medicine bag is provided with the injection tube inlet non-return valve that prevents that medicinal liquid from refluxing, and the connector that described injection tube is connected with described extraneous conduit is provided with the injection tube outlet non-return valve that prevents that medicinal liquid from refluxing.
CN2011101051079A 2011-04-26 2011-04-26 Hypodermic implantation type medicine feeder Pending CN102151346A (en)

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Application Number Priority Date Filing Date Title
CN2011101051079A CN102151346A (en) 2011-04-26 2011-04-26 Hypodermic implantation type medicine feeder

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Application Number Priority Date Filing Date Title
CN2011101051079A CN102151346A (en) 2011-04-26 2011-04-26 Hypodermic implantation type medicine feeder

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CN102151346A true CN102151346A (en) 2011-08-17

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109310820A (en) * 2016-04-21 2019-02-05 赛诺菲-安万特德国有限公司 Container for liquid preparation
CN113143581A (en) * 2021-04-13 2021-07-23 清华大学 Externally driven fluid drive device for biomedical applications

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1042301A (en) * 1988-10-31 1990-05-23 Avl股份公司 The determinator of material concentration in the organic organization
CN2304430Y (en) * 1997-07-18 1999-01-20 卫洪波 Medicine supplying pump
CN1744924A (en) * 2002-12-31 2006-03-08 艾富罗有限公司 Patient controlled drug administration device
CN2776414Y (en) * 2005-03-25 2006-05-03 李永峰 Multifunction encephalocoele external drain device
CN1951512A (en) * 2006-09-19 2007-04-25 武汉半边天医疗技术发展有限公司 Needle-free injection device
CN200942224Y (en) * 2006-09-19 2007-09-05 武汉半边天医疗技术发展有限公司 Microporous syringe
CN202061177U (en) * 2011-04-26 2011-12-07 上海白塔医药科技有限公司 Hypodermic implantation type drug administration device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1042301A (en) * 1988-10-31 1990-05-23 Avl股份公司 The determinator of material concentration in the organic organization
CN2304430Y (en) * 1997-07-18 1999-01-20 卫洪波 Medicine supplying pump
CN1744924A (en) * 2002-12-31 2006-03-08 艾富罗有限公司 Patient controlled drug administration device
CN2776414Y (en) * 2005-03-25 2006-05-03 李永峰 Multifunction encephalocoele external drain device
CN1951512A (en) * 2006-09-19 2007-04-25 武汉半边天医疗技术发展有限公司 Needle-free injection device
CN200942224Y (en) * 2006-09-19 2007-09-05 武汉半边天医疗技术发展有限公司 Microporous syringe
CN202061177U (en) * 2011-04-26 2011-12-07 上海白塔医药科技有限公司 Hypodermic implantation type drug administration device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109310820A (en) * 2016-04-21 2019-02-05 赛诺菲-安万特德国有限公司 Container for liquid preparation
US10918571B2 (en) 2016-04-21 2021-02-16 Sanofi-Aventis Deutschland Gmbh Container for a liquid medicament
CN113143581A (en) * 2021-04-13 2021-07-23 清华大学 Externally driven fluid drive device for biomedical applications

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Application publication date: 20110817