CN216908910U - Visual radioactive microsphere auxiliary drug delivery device - Google Patents

Visual radioactive microsphere auxiliary drug delivery device Download PDF

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Publication number
CN216908910U
CN216908910U CN202220056781.6U CN202220056781U CN216908910U CN 216908910 U CN216908910 U CN 216908910U CN 202220056781 U CN202220056781 U CN 202220056781U CN 216908910 U CN216908910 U CN 216908910U
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medicine
drug delivery
visual
pipeline
radioactive
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张钧
赵小生
张驰翔
路静
马文亮
白冰
荣茂凯
李中平
葛强
蔡继鸣
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Chengdu Nurit Medical Technology Co ltd
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Chengdu Nurit Medical Technology Co ltd
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Abstract

The utility model discloses a visual radioactive microsphere auxiliary drug delivery device, which comprises a transparent cylinder and a drug delivery pipeline system, wherein the transparent cylinder is used for accommodating and stably placing a drug bottle with radioactive microspheres; one end of the medicine delivery pipeline is inserted into the medicine, and the other end of the medicine delivery pipeline is connected to the pathological change part of the patient, so that a channel is provided for the medicine applied with outward discharge power to enter the pathological change part of the patient; the utility model can solve the technical problems of complex operation, large radiation exposure and complex operation process of the existing radiopharmaceutical infusion system; the simplicity, convenience, high efficiency and accuracy of the operation of the radioactive microsphere product in the drug administration process are realized, and the safety of medical personnel is ensured to the maximum extent.

Description

Visual radioactive microsphere auxiliary drug delivery device
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a visual radioactive microsphere auxiliary drug delivery device.
Background
Radioactive microsphere drugs are one of the main means of radio-embolization therapy. The hepatic artery interventional internal irradiation treatment plays an important role in the treatment of liver cancer which can not be removed by operation, and the treatment has the obvious advantages of minimal invasion, accuracy, safety, effectiveness and the like. The heart of achieving this treatment is the assisted delivery of a dose of radioactive microspheres into the target lesion site by hepatic artery interventional surgery. The radioactive microsphere products clinically used at present mainly comprise yttrium [90Y ] resin microspheres SIR-Spheres and yttrium [90Y ] glass microspheres TheraSphere. In the process of using such radiopharmaceuticals, due to the characteristics of the radiopharmaceuticals, the administration process of such radiopharmaceuticals is generally difficult to operate and high in safety risk, and the radiation absorbed dose of medical staff in the administration process increases along with the prolonging of the operation time and the shortening of the operation distance. Therefore, a set of radioactive microsphere auxiliary drug delivery devices with certain shielding capability is needed to simplify the drug delivery process, shorten the drug delivery time, increase the operation distance and reduce the safety risk; providing medical personnel with adequate radiation shielding.
The current yttrium [90Y ] resin microsphere SIR-Spheres matched infusion system is shown in a graph 1. When the medicine is administered, the operation is divided into two parts, firstly the dosage is calculated according to the tumor volume of a patient, then the product with the calculated dosage is extracted from a product bottle (not listed) of the patient, the product is filled into a special V-shaped bottle, then injection water is injected into the V-shaped bottle to pressurize and infuse the radioactive product to the lesion part of the patient, the three-way cock A and the three-way cock B are required to be repeatedly switched to control the switch in the administration process so as to realize the administration, and the product is required to be subjected to multiple component transfer in the administration process, so that the product is difficult to be in direct contact with the product bottle, the operator is easy to be irradiated by large dose, the safety is low, and the operation process is complicated.
Through the search discovery, patent number 201921126987.6's utility model discloses a radioactive suspension medicine infusion system, has carried out certain degree's optimization to above-mentioned drug delivery system as shown in fig. 2, has fixed the tee bend cock, realizes the control to the tee bend cock in the administration process through the valve control pole outside the shielded cell, has avoided operating personnel and radioactive direct contact, still has the operation complicacy, and the higher problem of misoperation risk. According to the design, the three-way valve is opened and closed by adjusting the three-way valve and the valve control rod, and a plurality of three-way cocks on the device need to be switched for many times in the operation process, so that complete delivery and administration of radioactive microspheres can be carried out. The whole administration process needs more control operations and is more complicated. The radioactive drug cleaning box has the advantages that the radioactive drug is operated by one more step, the risk of radioactive substance leakage is generated, operators are easy to radiate, the box body is designed to be square, the number of cleaning dead angles generated by more splicing parts is large, and the decontamination difficulty is large when radioactive pollution occurs.
Therefore, the technical personnel in the field need to break through how to realize the simplicity, high efficiency and precision of the operation of the radioactive microsphere product in the drug delivery process and ensure the safety of medical personnel to the maximum extent.
SUMMERY OF THE UTILITY MODEL
Therefore, in order to solve the technical problems of complex operation, large radiation exposure and complicated operation process of the existing radiopharmaceutical infusion system, the utility model provides the radioactive microsphere auxiliary drug delivery device.
Specifically, the visual radioactive microsphere auxiliary drug delivery device comprises
The transparent cylinder is used for accommodating and stably placing a medicine bottle with radioactive microspheres;
one end of the pressure pipeline is inserted into the medicine, the other end of the pressure pipeline is connected with the power component, and the power component provides power for discharging the medicine outwards; and
one end of the medicine delivery pipeline is inserted into the medicine, and the other end of the medicine delivery pipeline is connected to the pathological change part of the patient, so that a channel is provided for the medicine applied with outward discharge power to enter the pathological change part of the patient;
the pressure pipeline and the medicine delivery pipeline form a medicine delivery pipeline system.
Further, the medicine bottle is installed in the transparent cylinder body through the lead can, and a fixing groove used for stably placing the lead can is formed in the base of the transparent cylinder body.
Further, the transparent cylinder body is provided with a detachable cylinder cover.
Further, the pressure pipeline comprises a pressure applying main pipe,
the outlet end of the pressure main pipe is connected with a pressure pricker for inserting a medicine bottle, the inlet end is connected with a first one-way valve,
the inlet end of the first one-way valve is connected with a first three-way plug valve,
the other two interfaces of the first three-way plug valve are respectively connected with a micro-catheter interface and a second three-way plug valve,
the other two interfaces of the second three-way plug valve are respectively connected with a second one-way valve and a power injector,
the inlet end of the second one-way valve is communicated with a physiological saline bottle/bag through a pipeline.
Furthermore, the medicine feeding pipeline comprises a main medicine feeding pipe, the inlet end of the main medicine feeding pipe is connected with a medicine discharging puncture needle for inserting a medicine bottle, the outlet end of the main medicine feeding pipe is connected with a micro-catheter, and the main medicine feeding pipe is provided with a cut-off valve.
Furthermore, a positioner which is convenient for the medicine discharging puncture needle and the pressing puncture needle to be stably inserted into the medicine bottle is stably arranged at the upper end of the lead tank.
Furthermore, the bottom of the transparent cylinder body is designed in a water drop shape, and the water drop-shaped tip is provided with an independent metal rod for hanging a physiological saline bottle/bag.
Furthermore, a fixing buckle A for fixing the micro catheter is arranged outside the transparent cylinder body, and a fixing buckle B for fixing the pressure applying main pipe and the administration main pipe is arranged on the transparent cylinder body.
Further, the transparent cylinder is designed to be cylindrical, and the joint of the transparent cylinder and the bottom is designed to be a circular arc.
Further, the cover is transparent and adopts a design with a radioactive mark shape.
The utility model has the following beneficial effects:
the utility model has simple and convenient operation, the medical operator can complete the whole drug administration process by only 5 steps, and only the step of inserting the needle in the 5 steps is in close indirect contact with the radiopharmaceutical. However, due to the protection of the lead tank and the special locator, when inserting the needle, the medical staff can use the tweezers to clamp the injection needle corresponding to the administration pipeline and insert the injection needle according to the position of the locator, the whole process can be completed in about 10s, the operation time is extremely short, and therefore the irradiated level of the medical staff can be effectively reduced. And the control switch adjustment in the administration pipeline system is completed before the radioactive microsphere infusion, and the on-off adjustment is not needed in the administration process. Thereby greatly reducing the risk of errors in the administration operation of medical personnel. Simultaneously because increased the check valve among the administration pipe-line system and need not control the tee bend cock when making the in-process of dosing absorb liquid, and the inlet liquid pipeline of connecting the normal saline bag/bottle among the pipe-line system of will dosing prolongs, has increased the distance between medical staff and the radioactivity microballon. Based on the improvement, the irradiation level of medical staff is greatly reduced in time and distance, and the safety, convenience and high efficiency of the radioactive microsphere administration process are realized.
The transparent cylinder body is designed to be cylindrical, and the joint of the transparent cylinder body and the bottom is designed to be a circular arc, so that the generation of cleaning dead angles is effectively avoided, and the problem of difficulty in removing radioactive pollution when an emergency occurs in the operation process is effectively avoided.
Meanwhile, the copper cover of the transparent barrel is designed independently, convenience of the radiopharmaceuticals entering and exiting the barrel can be guaranteed, the appearance of the cover is in a radioactive warning mark structure (or clover shape), self-precaution consciousness of medical staff is improved, related staff is warned to use the radiopharmaceutically, and protection is well achieved.
The locator is reasonably designed in the utility model, the pressure application puncture needle and the medicine discharge puncture needle are respectively inserted into the medicine bottle from the pore canal corresponding to the locator to the bottom, the needle inserting process is protected by the locator, and the position of the needle is relatively fixed due to the existence of the locator, the needle inserting operation time is shortened, and the radiation dose is greatly reduced; and the administration process does not need any control operation, thereby greatly simplifying the administration flow, improving the administration efficiency and reducing the contact time of medical operators. In use, the cap of the lead can and the cap of the product bottle casing are opened before administration and replaced by a locator.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the present invention with the cover and administration line system removed;
FIG. 3 is a schematic top view of the state of FIG. 2;
FIG. 4 is a schematic cross-sectional view A-A of FIG. 3;
FIG. 5 is a schematic cross-sectional view of a vial set of the present invention mounted on a lead can and pierced with a pressure application spike and an expulsion spike;
FIG. 6 is a perspective view of the present invention with the support rod mounted to the base
FIG. 7 is a schematic structural view of a drug delivery line system according to the present invention;
FIG. 8 is a schematic view of the present invention in use;
in the figure: 1. a transparent cylinder; 2. a drug delivery tubing system; 2.1, a liquid inlet pipeline; 2.2, a second three-way plug valve; 2.3, a power component; 2.4, a liquid drainage pipeline; 2.5, a first three-way plug valve; 2.6, a pressure applying main pipe; 2.7, pressing a puncture needle; 2.8, medicine discharging prickling needles; 2.9, administration main; 2.10, microcatheter; 2.11, a stop valve; 2.12, a normal saline bottle/bag; 3. a base; 4. a support bar; 5. fixing the fastener A; 6. a card slot; 7. a clamping block; 8. a cylinder cover; 9. a lead can; 10. a medicine bottle group; 11. a locator.
Detailed Description
The present invention will be described in detail with reference to fig. 1 to 8, and the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
the utility model herein provides a visual radioactive microsphere assisted drug delivery device comprising
A transparent cylinder 1 for accommodating and stably placing a medicine bottle group 10 with radioactive microspheres;
one end of the pressure pipeline is inserted into the medicine bottle group 10, the other end of the pressure pipeline is connected with the power component 2.3, and the power for discharging the medicine outwards is given by the power component 2.3; and
one end of the medicine delivery pipeline is inserted into the medicine bottle group 10, and the other end of the medicine delivery pipeline is connected to the pathological change part of the patient, so that a channel is provided for the medicine applied with outward discharge power to enter the pathological change part of the patient;
the pressure pipeline and the medicine delivery pipeline form a medicine delivery pipeline system 2.
In this embodiment, the medicine bottle group 10 is installed in the transparent cylinder 1 through the lead can 9, and the fixing groove 3.1 for stably placing the lead can is opened on the base 3 of the transparent cylinder 1.
In this embodiment, the transparent cylinder is fitted with a removable cylinder cover 8.
In the present embodiment, the pressure line comprises a pressure main 2.6,
the outlet end of the pressure main pipe 2.6 is connected with a pressure spike 2.7 for inserting the medicine bottle group 10, the inlet end is connected with a first one-way valve,
the inlet end of the first one-way valve is connected with a first three-way plug valve 2.5,
the other two interfaces of the first three-way plug valve 2.5 are respectively connected with a micro-catheter interface and a second three-way plug valve 2.2, and the second three-way plug valve 2.2 is connected with the first three-way plug valve 2.5 through a liquid discharge pipeline 2.4;
the other two interfaces of the second three-way plug valve 2.2 are respectively connected with a second one-way valve and a power component 2.3 (an injector),
the inlet end of the second one-way valve is communicated with a physiological saline bottle/bag 2.12 through a liquid inlet pipeline 2.1.
In the embodiment, the medicine delivery pipeline comprises a main medicine delivery pipe 2.9, a medicine discharge puncture needle 2.8 for inserting the medicine bottle group is connected to the inlet end of the main medicine delivery pipe 2.9, a micro-duct 2.10 is connected to the outlet end of the main medicine delivery pipe 2.9, and a cut-off valve 2.11 is installed on the main medicine delivery pipe 2.9.
In this embodiment, the upper end of the lead can is firmly provided with a locator 11 for facilitating the stable insertion of the medicine discharging needle and the pressing needle into the medicine bottle group.
In this embodiment, the transparent barrel 1 is fixedly provided with a support rod 4 for hanging the physiological saline bottle/bag 2.12, and a fixture block 7 for fixing the support rod 4 is arranged on the outer wall of the transparent barrel 1.
In this embodiment, a fixing buckle a5 for fixing the micro catheter is provided outside the transparent cylinder, and a clamping groove 6 for fixing the main pressure applying pipe or the main administration pipe is provided on the transparent cylinder.
In the implementation process, the transparent cylinder is made of transparent acrylic materials, is 1-2cm thick and has certain beta-ray shielding capacity. The one-way valve, all pipelines and the three-way cock are all made of medical PVC plastics, and the medicine bottle is a V-shaped penicillin bottle including but not limited to a special-shaped penicillin bottle.
The utility model is implemented as follows:
the working principle is as follows: suspending a physiological saline bottle/bag 2.12 on a metal rod 4, inserting a bottle pricking device of a liquid inlet pipeline into the physiological saline bottle/bag, filling all pipelines with physiological saline by sucking and injecting by a power component (selecting an injector) 2.3, and closing all switches in the pipelines, wherein in the process, the liquid outlet end of a main administration pipe 2.9 is connected with a first three-way plug valve 2.5; opening a cylinder cover 8, putting a lead cylinder with a medicine bottle group 10 into a lead cylinder fixing groove 3.1 in a transparent cylinder, opening a lead cylinder cover, wherein a medicine bottle is arranged in the lead cylinder, wiping and disinfecting the top end of the medicine bottle by medical alcohol cotton, covering a special positioner 11 at a concave part corresponding to a medicine bottle sleeve part, respectively inserting a pressure application puncture needle 2.7 of a pressure pipeline and a medicine discharge puncture needle 2.8 of a medicine delivery pipeline into the medicine bottle from a pore passage corresponding to the positioner to the bottom, then disconnecting a main medicine delivery pipe 2.9 from a first three-way plug valve 2.5, and connecting a liquid outlet end of the main medicine delivery pipe 2.9 to a micro catheter 2.10 leading to a focus of a human body; will administer and be responsible for and the pressure line is placed in draw-in groove 6 that corresponds on transparent barrel, covers the cover, opens second three way plug valve 2.2 and first three way plug valve 2.5, absorbs normal saline through power part (selecting for use syringe) 2.3 ration, and the back is slowly injected and is injected the radioactivity micro-sphere suspension and inject to patient's pathological change position through being responsible for 2.9 and the little pipe 2.10 of connection of dosing, accomplishes and doses. The radioactive rays are shielded in the whole operation process, and meanwhile, on-off control is not needed during radioactive microsphere infusion, so that remote administration of the medicine can be realized. The direct and indirect contact time of medical operators is greatly reduced, and the safety and the high efficiency of the drug administration process are ensured.
Example two:
the embodiment is further optimized on the basis of the embodiment 1, and specifically, the transparent cylinder is designed to be circular and is embedded on the water drop type base 3, and the cylinder is sealed relatively by matching with the cylinder cover.
In this embodiment, the cover 8 is a movable independent unit, which can ensure the convenience of the radiopharmaceutical entering and exiting the barrel, and the appearance design of the cover adopts the structure (or clover shape) of a radioactive warning sign, which can directly reflect the purpose of the device, warn medical staff to use carefully, and protect the device. When the pollution exists in the cylinder body, the cylinder cover is covered, so that the error contact of personnel can be effectively avoided. There is not dead angle gomphosis between water droplet type base and the barrel, effectively avoids the pollutant to get into gap and the unable problem of dispelling in dead angle, and water droplet type base design makes the device more possess aesthetic value, and the patient can reduce psychological pressure and conflict mood at the treatment in-process to the better acceptance therapy of the mood of relaxing.
EXAMPLE III
The embodiment is further optimized on the basis of the embodiment 1, and particularly, the administration management pipeline system 2 is a designed independent sterile packaging whole; through the cooperation of the transparent cylinder, the radioactive microsphere product and the interventional micro catheter, the control of the corresponding joint and the switch can be completed before radioactive microsphere infusion. Because the one-way valve is added in the pipeline system, the valve and the switch do not need to be controlled in the radioactive microsphere administration process; meanwhile, the extension of the front end pressure extension tube enables a medical operator to be far away from the radioactive source in the administration process, and the shielding protection and distance protection of the radioactive source are realized. Greatly reducing the hand irradiation dose of operators.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the utility model. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (8)

1. A visual radioactive microsphere assisted drug delivery device, characterized in that: comprises that
A transparent cylinder for accommodating and stably placing the medicine bottle group with the radioactive microspheres;
one end of the pressure pipeline is inserted into the medicine bottle group, the other end of the pressure pipeline is connected with the power component, and the power component provides power for the medicine to be discharged outwards; and
one end of the medicine delivery pipeline is inserted into the medicine bottle group, and the other end of the medicine delivery pipeline is connected to the pathological change part of the patient, so that a channel is provided for the medicine applied with outward discharge power to enter the pathological change part of the patient;
the pressure pipeline and the medicine delivery pipeline form a medicine delivery pipeline system.
2. The visual radioactive microsphere assisted drug delivery device of claim 1, wherein: the medicine bottle group is arranged in the transparent cylinder body through the lead tank, and a fixing groove used for stably placing the lead tank is formed in the base of the transparent cylinder body.
3. The visual radioactive microsphere assisted drug delivery device of claim 1, wherein: the transparent cylinder body is provided with a detachable cylinder cover.
4. The visual radioactive microsphere assisted drug delivery device of claim 2, wherein: the pressure pipeline comprises a pressure applying main pipe,
the outlet end of the pressure main pipe is connected with a pressure pricker for inserting the medicine bottle group, the inlet end is connected with a first one-way valve,
the inlet end of the first one-way valve is connected with a first three-way plug valve,
the other two interfaces of the first three-way plug valve are respectively connected with a micro-catheter interface and a second three-way plug valve,
the other two interfaces of the second three-way plug valve are respectively connected with a second one-way valve and a power injector,
the inlet end of the second one-way valve is communicated with a physiological saline bottle/bag through a liquid inlet pipeline.
5. The visual radioactive microsphere assisted drug delivery device of claim 4, wherein: the medicine feeding pipeline comprises a main medicine feeding pipe, the inlet end of the main medicine feeding pipe is connected with a medicine discharging puncture needle used for being inserted into the medicine bottle group, the outlet end of the main medicine feeding pipe is connected with a micro-duct, and the main medicine feeding pipe is provided with a cut-off valve.
6. The visual radioactive microsphere assisted drug delivery device of claim 5, wherein: and the upper end of the lead tank is stably provided with a positioner which is convenient for the medicine discharging pricker and the pressure applying pricker to be stably inserted into the medicine bottle group.
7. The visual radioactive microsphere assisted drug delivery device of claim 1, wherein: the transparent cylinder body is fixedly provided with a supporting rod for hanging a physiological saline bottle/bag.
8. The visual radioactive microsphere assisted drug delivery device of claim 1, wherein: the transparent cylinder body is externally provided with a fixing buckle A for fixing the micro catheter, and the transparent cylinder body is provided with a clamping groove for fixing the pressure applying main pipe or the administration main pipe.
CN202220056781.6U 2022-01-11 2022-01-11 Visual radioactive microsphere auxiliary drug delivery device Active CN216908910U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2804991C1 (en) * 2022-12-23 2023-10-09 Общество с ограниченной ответственностью "БЕБИГ" Device for intraarterial administration of suspensions and solutions, allowing contrasting of target artery

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2804991C1 (en) * 2022-12-23 2023-10-09 Общество с ограниченной ответственностью "БЕБИГ" Device for intraarterial administration of suspensions and solutions, allowing contrasting of target artery

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