CN201324434Y - Embedded refilling hypodermic slow release dosing pump - Google Patents
Embedded refilling hypodermic slow release dosing pump Download PDFInfo
- Publication number
- CN201324434Y CN201324434Y CNU2008201578733U CN200820157873U CN201324434Y CN 201324434 Y CN201324434 Y CN 201324434Y CN U2008201578733 U CNU2008201578733 U CN U2008201578733U CN 200820157873 U CN200820157873 U CN 200820157873U CN 201324434 Y CN201324434 Y CN 201324434Y
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- pump
- medicinal liquid
- administration
- pump housing
- elastic force
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Abstract
The utility model relates to an embedded refilling hypodermic slow release dosing pump, which comprises a pump body, an elastic puncture membrane, an inner duct, a drainage valve and a dosing sieve, wherein the pump body and the elastic puncture membrane form an inner cavity by a fixing sealing ring via pressing or adhering, the elastic puncture membrane can bounce after being filled with liquid medicine, and then enables the inner cavity to expand to 5-30 ml volume to contain liquid medicine in corresponding volume. The pump body is provided with fixing holes for fixedly sewing the pump body to human body hypodermia. Further, the inner cavity is communicated with the dosing sieve via the inner duct, the drainage valve is arranged on the inner duct, and the flow rate of liquid medicine in the inner cavity flowing from the dosing sieve to hypodermia is controlled by adjusting the drainage valve. The pump body has simple structure, low cost, safety and reliability, and can be filled with medicine repeatedly.
Description
Technical field
This utility model relates to a kind of medical treatment device that is used in the subcutaneous depot administration, belongs to medical apparatus and instruments, and particularly, it relates to a kind of subcutaneous filled subcutaneous depot administration pump of human body that is embedded in.
Background technology
In existing medical procedure, some disease (as, malignant tumor, endocrinopathy etc.) need drug administration by injection under the long-term percutaneous usually, the patient must be every other day in addition every day hospital or medical institutions' injectable drug for several times, bring great inconvenience for patient's work, life, the injection site also may produce untoward reaction such as scleroma, ulceration owing to prolonged and repeated injection; In addition, some medicine since in vivo the half-life short, intermittently heavy dose of administration is difficult to continue in vivo to keep onset concentration, and the toxic and side effects of medicine also can increase because the dosage of administration at intermittence is excessive.Therefore, the needs exploitation is a kind of can be embedded in the subcutaneous doser of human body, in order to continue the discharging effective dose of medicine thing lentamente in vivo, and as possible, also wish to repeat to charge into medicine, thereby can use repeatedly, the saving cost also reduces the patient and repeats embedding misery.
Summary of the invention
Problem to be solved in the utility model is to overcome the deficiencies in the prior art, provides to be embedded in the subcutaneous administration pump that can continue to discharge lentamente the effective dose of medicine thing in vivo of human body.Particularly, the purpose of this utility model is to provide a kind of sustained-release administration pump that is used for the body embedded set, when charging into medicine, pierce through the elastic force puncture film that is embedded on this subcutaneous pump housing with the injection needle percutaneous, injecting liquid drug is arrived in the pump housing inner chamber, elastic force puncture film passive raising up of meeting in intracavity medicine stowing operation, produce certain resilient pressure during elastic force puncture film projection, pump housing intracavity medicine is pumped to inner catheter and administration sieve direction, scalable diaphragm valve on the inner catheter matches with elastic force puncture film, control medicine stream is slowly at the uniform velocity to subcutaneous infiltration, by regulate diaphragm valve make certain volume in the pump housing (as, medicinal liquid 15ml) slowly pumped in a couple of days to several weeks, thereby satisfied the treatment needs of clinical various disease.This sustained-release administration pump good biocompatibility does not have toxic and side effects and anaphylaxis; Have the design of excellent drug antiseep, safe and reliable; By this device can be implemented in the human body automatically, the administering mode of slow release, medicine continues medication through slow release, more meets pharmacokinetics and Human Physiology needs, can reduce the toxic and side effects of chemotherapeutic etc., the raising curative effect.This sustained-release administration pump can be used for the administration of the medicine of the chemotherapy (as 5-fluorouracil etc.) of prevention of recurrence behind cancer chemotherapy and the tumor resection, biological immune treatment (as interferon, thymosin etc.), the ache in late cancer pain management of tumour patient (as the morphine class etc.), endocrinopathy hormone replacement therapy numerous areas such as (as insulin, estrogen), has broad application prospects.
The purpose of this utility model comes to be realized by the following technical programs.Particularly, this utility model provides a kind of sustained-release administration pump that is used for the body embedded set, it comprises the pump housing 2, elastic force puncture film 5, inner catheter 6, diaphragm valve 7 and administration sieve 9, it is characterized in that, the pump housing 2 is pressed or is adhered to by embedding by fixed seal ring 4 with elastic force puncture film 5 and forms an inner chamber 3, this elastic force puncture film 5 can be upspring after injecting medicinal liquid, makes inner chamber 3 expand the 5-30ml volume to and holds the medicinal liquid of respective volume; Be useful on the pump housing 2 pump housing sutured in the subcutaneous fixing hole 1 of human body; And, be connected by inner catheter 6 between inner chamber 3 and the administration sieve 9, have diaphragm valve 7 on the inner catheter 6, control medicinal liquid in the inner chamber 3 and flow out administration sieve 9 and enter subcutaneous flow velocity by regulating diaphragm valve 7.It is subcutaneous that this sustained-release administration pump is embedded into human body when can not inject medicinal liquid, can alleviate the misery that the process of inserting is given the patient like this; Be embedded into human body subcutaneous after, can medicinal liquid be injected inner chamber 3 by syringe.When not injecting medicinal liquid, inner chamber 3 volumes are less than 15ml, and preferable volume is 0ml; By the injection of medicinal liquid, elastic force puncture film 5 is upspring, during as injection medicinal liquid 15ml, hold this medicinal liquid just can make inner chamber 3 expand the 15ml volume to.According to the use amount of conventional medicinal liquid, in above-mentioned sustained-release administration pump, elastic force puncture film 5 can be upspring after injecting medicinal liquid, makes inner chamber 3 expand the 15ml volume to and holds the medicinal liquid of 15ml.
Preferably in above-mentioned sustained-release administration pump, the chamber pressure that the resilience force that elastic force puncture film 5 relies on self-deformations to produce causes between 10-100Pa, and repeatedly after flexible 200 times resilience force descend and be no more than 2Pa.Like this under the effect of the resilience force that elastic force puncture film 5 self-deformations produce, by regulating the pod apertures 8 on the diaphragm valve 7, can realize administering mode automatic, slow, that continue, make medicinal liquid pump from the tissue of administration sieve 9 outside pump through inner catheter 6 at last.
Preferably in above-mentioned sustained-release administration pump, be useful on the pump housing 2 pump housing 2 sutured in 4 subcutaneous fixing holes 1 of human body.So preferred fixing hole 1 quantity is convenient to being embedded in human body securely subcutaneous.
Preferably in above-mentioned sustained-release administration pump, the medicinal liquid flow velocity of diaphragm valve 7 controls is between 0.5ml/ hour to 0.01ml/ hour.Like this, just may command 15ml dose slowly at the uniform velocity pumped to 1 week at 1 day, met the demand of real administration.
Above-mentioned sustained-release administration pump can use conventional material to make, and can buy by market.For example, insert the material of human body makes with tissue contact portion being used to of using that those skilled in the art used always, material therefor is biocompatible polymer material or biological alloy, can there be repulsion with tissue like this, for example the pump housing 2 can be with medical polysulfones manufacturing, administration sieve 9 can be used the biocompatible alloy manufacturing, and elastic force puncture film 5 available silicon rubber are made, and it is non-leakage to make elastic force puncture film can tolerate thousands of inferior punctures like this.
The sustained-release administration pump that is used for the body embedded set that this utility model provides has following multiple beneficial effect: 1, can place subcutaneous for a long time, pump housing sutured and puncture location are easily, pump housing sealing, histocompatibility are good, medicinal liquid does not have the dystopy seepage, and is safe and reliable, so patient need not to be in hospital during the administration, but orthobiosis, work, thereby greatly improve quality of life of patient; 2, can be after this device implants repeatedly through subcutaneous dabbling drug, treatment can be finished in outpatient service, and doctor and patient can be according to laying one's hand on and subcutaneous pump housing surface elastic force film shape is learnt pump housing giving drugs into nose quantitative changeization, promptly point out medicine to use up as recover depression fully from the protuberance state, can load medicine again, so expense is cheap, easy to operate; 3, this pump configuration is simple, low cost of manufacture.
Description of drawings
Fig. 1 is the structural representation that is used for the sustained-release administration pump of body embedded set of the present utility model, has shown each parts and the annexation of this sustained-release administration pump.Wherein, the relation of Reference numeral and parts is as follows: 1. fixing hole; 2. the pump housing; 3. inner chamber; 4. fixed seal ring; 5. elastic force puncture film; 6. inner catheter; 7. diaphragm valve; 8. pod apertures; 9. administration is sieved.
The specific embodiment
Below in conjunction with accompanying drawing formation of the present utility model is further described:
Instantiation and accompanying drawing are illustrated sustained-release administration pump of the present utility model.Yet, should be understood that the instantiation that provides only is in order to illustrate that obviously those of ordinary skill in the art can make various corrections and change to the present invention within the scope of the invention according to detailed description.
Claims (5)
1. sustained-release administration pump that is used for the body embedded set, it comprises the pump housing (2), elastic force puncture film (5), inner catheter (6), diaphragm valve (7) and administration sieve (9), it is characterized in that, the pump housing (2) is pressed or is adhered to by embedding by fixed seal ring (4) with elastic force puncture film (5) and forms an inner chamber (3), this elastic force puncture film (5) can be upspring after injecting medicinal liquid, makes inner chamber (3) expand the 5-30ml volume to and holds the medicinal liquid of respective volume; Be useful on pump housing sutured on the pump housing (2) in the subcutaneous fixing hole of human body (1); And inner chamber (3) sieves between (9) with administration and is connected by inner catheter (6), has diaphragm valve (7) on the inner catheter (6), and the medicinal liquid outflow administration sieve of controlling in the inner chamber (3) by adjusting diaphragm valve (7) (9) enters subcutaneous flow velocity.
2. sustained-release administration pump according to claim 1 is characterized in that, the chamber pressure that the resilience force that elastic force puncture film (5) relies on self-deformation to produce causes between 10-100Pa, and repeatedly after flexible 200 times resilience force descend and be no more than 2Pa.
3. sustained-release administration pump according to claim 1 is characterized in that, is useful on the pump housing (2) pump housing sutured in subcutaneous 4 fixing holes (1) of human body.
4. sustained-release administration pump according to claim 1 is characterized in that, the medicinal liquid flow velocity of diaphragm valve (7) control is between 0.5ml/ hour to 0.01ml/ hour.
5. sustained-release administration pump according to claim 1 is characterized in that, this elastic force puncture film (5) can be upspring after injecting medicinal liquid, makes inner chamber (3) expand the 15ml volume to and holds the medicinal liquid of 15ml.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNU2008201578733U CN201324434Y (en) | 2008-12-25 | 2008-12-25 | Embedded refilling hypodermic slow release dosing pump |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNU2008201578733U CN201324434Y (en) | 2008-12-25 | 2008-12-25 | Embedded refilling hypodermic slow release dosing pump |
Publications (1)
Publication Number | Publication Date |
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CN201324434Y true CN201324434Y (en) | 2009-10-14 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CNU2008201578733U Expired - Fee Related CN201324434Y (en) | 2008-12-25 | 2008-12-25 | Embedded refilling hypodermic slow release dosing pump |
Country Status (1)
Country | Link |
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CN (1) | CN201324434Y (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102872527A (en) * | 2012-10-10 | 2013-01-16 | 广州医学院 | Percutaneously implanted diffusion medicine deliver and method for manufacturing same |
CN108837298A (en) * | 2018-06-21 | 2018-11-20 | 浙江大学 | A kind of subcutaneous medicament delayed release device |
-
2008
- 2008-12-25 CN CNU2008201578733U patent/CN201324434Y/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102872527A (en) * | 2012-10-10 | 2013-01-16 | 广州医学院 | Percutaneously implanted diffusion medicine deliver and method for manufacturing same |
CN102872527B (en) * | 2012-10-10 | 2014-04-23 | 广州医学院 | Percutaneously implanted diffusion medicine deliver and method for manufacturing same |
CN108837298A (en) * | 2018-06-21 | 2018-11-20 | 浙江大学 | A kind of subcutaneous medicament delayed release device |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20091014 Termination date: 20141225 |
|
EXPY | Termination of patent right or utility model |