RU2238111C2 - Implantable system for carrying out controlled infusion - Google Patents

Abstract

FIELD: medical engineering.

SUBSTANCE: device has reservoir for keeping dosing liquid. The reservoir is connected by tube for supplying liquid to manually driven liquid-supplying pump for moving liquid from storage reservoir to outlet catheter via pipe for discharging measured dose. The pipe for discharging liquid has a unit for initiating movement of liquid. The pump has casing having pressurizing and dosing chamber separated with rigid partition perforated in the peripheral zone and having flexible membrane disposed in central zone on the same side with pumping chamber to close the perforated holes.

EFFECT: simplified design; high reliability of operation.

2 dwg

Description

The invention relates to medical equipment, in particular to implantable systems for prolonged dosed administration of drugs, that is, for dosed infusion, into the patient’s body in the treatment of various diseases.

This is especially important in the treatment of patients suffering from continuous pain, for example, terminally ill patients who need a constant amount of painkillers administered to reduce the pain effect.

Previously, for the dosed administration of drugs, patients were offered systems containing pumps that regulate the supply of drugs, driven by an energy source. Typically, such systems are subcutaneously mounted on the body and, using a connected catheter, the drug is delivered to the desired location. However, such systems are very expensive and use a power source in the event of failure of which the system must be replaced.

Closest to the proposed technical solution is a system for metered administration of drugs containing a reservoir for storing a dosed liquid, connected by a fluid supply pipe to a manually driven fluid transfer pump from the storage tank to the outlet catheter through a discharge pipe containing a fluid transfer activation device (US No. 5085644 )

When using such systems, the pump is installed subcutaneously and is actuated by the patient to supply the drug when the need arises for such a drug.

Pressure chambers in such systems are designed in such a way that they spontaneously occupy the position of maximum volume, and when exposed to a patient, they are reduced to a minimum volume. In this case, the repeated flow of liquid into the chamber is controlled by means of a capillary so that the pump can supply liquid after a certain period of time.

The disadvantage of such systems is that the flow of drugs to the patient will decrease due to the outflow of fluid into the fluid storage tank when the pump is pressed.

The problem solved by the claimed invention is the creation of an implantable system that delivers the full required dose of the drug.

Achievement of technical results - simplicity and reliability of the device, as well as ensuring the guaranteed administration of a dose of medication prescribed to the patient, is carried out due to the fact that the implantable system containing a reservoir for storing the dosing fluid, connected by a fluid supply pipe to a manually driven fluid transfer pump from the storage tank to the outlet catheter through a metered dose tap containing device for activating the movement of fluid, including us sa proposed design. The pump contains a housing in which the injection and metering chambers are located, separated by a rigid partition with holes at the edges and with an elastic membrane located centrally on the side of the injection chamber, overlapping the holes in the partition, and the pump chamber is made with the possibility of spontaneous acceptance of the maximum volume.

This design is quite simple and ensures reliable operation and the absence of reverse drug flow, that is, the receipt of a full measured dose of the drug to the patient.

The system is made of special grades of silicone rubber and is intended for subcutaneous implantation for the purpose of drug delivery.

Figure 1 shows a schematic representation of the structural design of the system.

Figure 2 shows the pump.

The system comprises a drug storage tank 1 connected to an injection unit 3 for filling the drug storage tank 1 by administration via an injection needle. The injection unit 3 is connected through a filter 4 using a channel 2 with a pipe 6 for supplying liquid.

The system also includes a pump 5 located in the patient’s body so that the patient can control it, and connected by a fluid supply pipe 6 to the drug storage tank 1. The pump 5 is controlled by pressing the dome of the discharge chamber.

The pump 5 (figure 2) contains a discharge chamber 7 spontaneously accepting a state of maximum volume (provided, in particular, by the elastic properties of the structure). Due to the compression of the chamber 7 as a result of the patient’s actions, it decreases in volume to deliver the contents under the action of the applied force. The injection chamber 7 is separated by a rigid partition 8 from the metering chamber 9, which is equipped with a limiter-regulator 10 that controls the flow rate of the liquid. In the central part of the partition, an elastic membrane 11 is rigidly fixed, which fits tightly to the holes 12 of the rigid partition and overlaps the holes 12 in it. A device for activating the movement of fluid 13 is integrated in the discharge pipe for the measured dose of fluid, which, for example, can be a normally closed valve (in particular, as in US Pat. No. 5,085,644), which opens when the patient presses and allows the liquid drug to enter into the outlet catheter 14.

When the patient is pressed on the pump 5 and the device for activating the movement of the liquid 13, the pressure chamber 7 of the pump 5 is compressed, the membrane 11 of which is squeezed from the holes 12 of the septum, providing a one-way fluid flow from the chamber 7 through the valve of the device for activating the movement of the liquid 13 into the outlet catheter 14.

When you press the pump 5 again, provided that there is no effect on the device for activating the movement of fluid 13, that is, the outlet to the outlet catheter 14 is blocked by a normally closed valve, the injection chamber 7 is re-filled with medicine due to the elastic properties of its walls.

The system is implanted subcutaneously, the injection unit 3 being located in a convenient place for injection on the body, and the pump 5 and the device for activating the movement of fluid 13 are located where they are accessible to the patient.

The outlet catheter 14 is located in the corresponding part of the body depending on the purpose of the system. The dimensions of the device are such that it can be installed in the body through a small incision.

After the system is installed, the reservoir 1 for storing drugs is filled through the injection node 3 with the drug. Then, to actuate the system, the patient controls the pump 5 by repeatedly squeezing the chamber 7 so as to cause the drug to flow from the storage tank 1 into the metering chamber 9 and then through the openings 12 in the rigid partition 8 into the discharge chamber 7. The valve of the device 13 activating fluid movement closed.

When the discharge chamber 7 reaches its maximum volume, any further patient exposure to the pump 5 does not cause an additional supply of medicine to the catheter until the device activating the movement of fluid 13 is activated, which protects the device from accidental (unauthorized) operation.

Claims (1)

An implantable system for dosed infusion containing a reservoir for storing a dosed fluid, connected by a fluid supply pipe to a manually driven fluid transfer pump from the storage tank to the outlet catheter via a measured liquid dose withdrawal pipe, wherein the liquid discharge pipe contains a fluid transfer activation device, characterized in that the pump contains a housing in which the discharge and metering chambers are located, separated by a rigid partition with holes on the edges and positioned on the center side of the pump chamber flexible membrane overlying the hole in the wall, wherein the pump chamber is configured to spontaneous taking maximum volume.

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